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Volumn 5, Issue 8, 2006, Pages 1909-1917

Nanotechnology in cancer therapeutics: Bioconjugated nanoparticles for drug delivery

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOSTATIN; ANTINEOPLASTIC AGENT; BEVACIZUMAB; CAMPTOTHECIN; CETUXIMAB; CONTRAST MEDIUM; DAUNORUBICIN; DOXORUBICIN; DRUG RECEPTOR; ENDOSTATIN; GELATINASE A; GEMTUZUMAB OZOGAMICIN; GENEXOL PM; IPILIMUMAB; LECTIN; LIPOSOME; MACROGOL; MALEIMIDE DERIVATIVE; METHOTREXATE; MITOMYCIN; NANOPARTICLE; PACLITAXEL; PACLITAXEL POLIGLUMEX; PERTUZUMAB; POLYGLACTIN; PROTEIN P53; RITUXIMAB; SEMAXANIB; TACROLIMUS; TRASTUZUMAB; UNCLASSIFIED DRUG; UNINDEXED DRUG; VITRONECTIN RECEPTOR;

EID: 33748344520     PISSN: 15357163     EISSN: None     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-06-0141     Document Type: Review
Times cited : (707)

References (69)
  • 1
    • 0030217418 scopus 로고    scopus 로고
    • Perspectives on the physical chemistry of semiconductor nanocrystals
    • Alivisatos A. Perspectives on the physical chemistry of semiconductor nanocrystals. J Phys Chem 1996;100:13226-39.
    • (1996) J Phys Chem , vol.100 , pp. 13226-13239
    • Alivisatos, A.1
  • 2
    • 0036705946 scopus 로고    scopus 로고
    • Quantum dots as luminescent probes in biological systems
    • Suntherland A. Quantum dots as luminescent probes in biological systems. Curr Opin Solid State Mater Sci 2002;6:36-370.
    • (2002) Curr Opin Solid State Mater Sci , vol.6 , pp. 36-370
    • Suntherland, A.1
  • 3
    • 33748349897 scopus 로고    scopus 로고
    • American Pharmaceutical Partners announces presentation of Abraxane survival data
    • In: Miami, FL
    • Perez E. American Pharmaceutical Partners announces presentation of Abraxane survival data. In: 22nd annual Miami Breast Cancer Conference; Miami, FL, 2005.
    • (2005) 22nd Annual Miami Breast Cancer Conference
    • Perez, E.1
  • 4
    • 0141955909 scopus 로고    scopus 로고
    • Nanoparticle drug delivery system for intravenous delivery of topoisomerase inhibitors
    • Williams J, Lansdown R, Sweitzer R, et al. Nanoparticle drug delivery system for intravenous delivery of topoisomerase inhibitors. J Control Release 2003;91:167-72.
    • (2003) J Control Release , vol.91 , pp. 167-172
    • Williams, J.1    Lansdown, R.2    Sweitzer, R.3
  • 5
    • 0343026322 scopus 로고    scopus 로고
    • Biodegradable nanoparticles - From sustained release formulation to improved site specific drug delivery
    • Leroux J-C, Allemann E, De Jaeghere F, Duelker E, Gurny R. Biodegradable nanoparticles - From sustained release formulation to improved site specific drug delivery. J Control Release 1996;30:339-50.
    • (1996) J Control Release , vol.30 , pp. 339-350
    • Leroux, J.-C.1    Allemann, E.2    De Jaeghere, F.3    Duelker, E.4    Gurny, R.5
  • 6
    • 0016622773 scopus 로고
    • Structure and properties of pharmacologically active polymers
    • Ringdorf H. Structure and properties of pharmacologically active polymers. J Polym Sci Symp 1975;51:135-53.
    • (1975) J Polym Sci Symp , vol.51 , pp. 135-153
    • Ringdorf, H.1
  • 7
    • 0024839642 scopus 로고
    • Tumoritropic and lymphotropic principles of macromolecular drugs
    • Maeda H, Matsumura Y. Tumoritropic and lymphotropic principles of macromolecular drugs. Crit Rev Ther Drug Carrier Syst 1989;6:193-210.
    • (1989) Crit Rev Ther Drug Carrier Syst , vol.6 , pp. 193-210
    • Maeda, H.1    Matsumura, Y.2
  • 8
    • 0032489812 scopus 로고    scopus 로고
    • Targeted delivery of chemotherapeutics: Tumor-activated prodrug therapy
    • Chari RV. Targeted delivery of chemotherapeutics: tumor-activated prodrug therapy. Adv Drug Deliv Rev 1998;31:89-104.
    • (1998) Adv Drug Deliv Rev , vol.31 , pp. 89-104
    • Chari, R.V.1
  • 9
    • 0042173127 scopus 로고    scopus 로고
    • A new approach for the treatment of malignant melanoma: Enhanced antitumor efficacy of an albuminbinding doxorubicin prodrug that is cleaved by matrix metalloproteinase 2
    • Mansour AM, Drevs J, Esser N, et al. A new approach for the treatment of malignant melanoma: enhanced antitumor efficacy of an albuminbinding doxorubicin prodrug that is cleaved by matrix metalloproteinase 2. Cancer Res 2003;63:4062-6.
    • (2003) Cancer Res , vol.63 , pp. 4062-4066
    • Mansour, A.M.1    Drevs, J.2    Esser, N.3
  • 10
    • 0038518258 scopus 로고    scopus 로고
    • Chemical approaches to triggerable lipid vesicles for drug and gene delivery
    • Guo X, Szoka FC, Jr. Chemical approaches to triggerable lipid vesicles for drug and gene delivery. Acc Chem Res 2003;36:335-41.
    • (2003) Acc Chem Res , vol.36 , pp. 335-341
    • Guo, X.1    Szoka Jr., F.C.2
  • 11
    • 0037458828 scopus 로고    scopus 로고
    • Tumor regression by repeated intratumoral delivery of water soluble lipopolymers/p2CMVmIL-12 complexes
    • Yockman JW, Maheshwari A, Han SO, Kim SW. Tumor regression by repeated intratumoral delivery of water soluble lipopolymers/p2CMVmIL-12 complexes. J Control Release 2003;87:177-86.
    • (2003) J Control Release , vol.87 , pp. 177-186
    • Yockman, J.W.1    Maheshwari, A.2    Han, S.O.3    Kim, S.W.4
  • 12
    • 0032584134 scopus 로고    scopus 로고
    • Pharmacokinetic characteristics and therapeutic effects of mitomycin C-dextran conjugates after intratumoural injection
    • Nomura T, Saikawa A, Morita S, et al. Pharmacokinetic characteristics and therapeutic effects of mitomycin C-dextran conjugates after intratumoural injection. J Control Release 1998;52:239-52.
    • (1998) J Control Release , vol.52 , pp. 239-252
    • Nomura, T.1    Saikawa, A.2    Morita, S.3
  • 13
    • 22444444015 scopus 로고    scopus 로고
    • Nanoparticle-mediated wild-type p53 gene delivery results in sustained antiproliferative activity in breast cancer cells
    • Prabha S, Labhasetwar V. Nanoparticle-mediated wild-type p53 gene delivery results in sustained antiproliferative activity in breast cancer cells. Mol Pharmacol 2004;1:211-9.
    • (2004) Mol Pharmacol , vol.1 , pp. 211-219
    • Prabha, S.1    Labhasetwar, V.2
  • 14
    • 0023099280 scopus 로고
    • Adenovirus proteins from both E1B reading frames are required for transformation of rodent cells by viral infection and DNA transfection
    • Barker DD, Berk AJ. Adenovirus proteins from both E1B reading frames are required for transformation of rodent cells by viral infection and DNA transfection. Virology 1987;156:107-21.
    • (1987) Virology , vol.156 , pp. 107-121
    • Barker, D.D.1    Berk, A.J.2
  • 15
    • 0033831080 scopus 로고    scopus 로고
    • A controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer
    • Khuri FR, Nemunaitis J, Ganly I, et al. a controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer. Nat Med 2000;6:879-85.
    • (2000) Nat Med , vol.6 , pp. 879-885
    • Khuri, F.R.1    Nemunaitis, J.2    Ganly, I.3
  • 16
    • 0037314610 scopus 로고    scopus 로고
    • A phase I/II trial of intratumoral endoscopic ultrasound injection of ONYX-015 with intravenous gemcitabine in unresectable pancreatic carcinoma
    • Hecht JR, Bedford R, Abbruzzese JL, et al. A phase I/II trial of intratumoral endoscopic ultrasound injection of ONYX-015 with intravenous gemcitabine in unresectable pancreatic carcinoma. Clin Cancer Res 2003;9:555-61.
    • (2003) Clin Cancer Res , vol.9 , pp. 555-561
    • Hecht, J.R.1    Bedford, R.2    Abbruzzese, J.L.3
  • 17
    • 0036828125 scopus 로고    scopus 로고
    • Hepatic arterial infusion of a replication-selective oncolytic adenovirus (dl 1520): Phase II viral, immunologic, and clinical endpoints
    • Reid T, Galanis E, Abbruzzese J, et al. Hepatic arterial infusion of a replication-selective oncolytic adenovirus (dl 1520): phase II viral, immunologic, and clinical endpoints. Cancer Res 2002;62:6070-9.
    • (2002) Cancer Res , vol.62 , pp. 6070-6079
    • Reid, T.1    Galanis, E.2    Abbruzzese, J.3
  • 18
    • 0037087621 scopus 로고    scopus 로고
    • Phase I trial of intraperitoneal injection of the E1B-55-kd-gene-deleted adenovirus ONYX-015 (dl 1520) given on days 1 through 5 every 3 weeks in patients with recurrent/refractory epithelial ovarian cancer
    • Vasey PA, Shulman LN, Campos S, et al. Phase I trial of intraperitoneal injection of the E1B-55-kd-gene-deleted adenovirus ONYX-015 (dl 1520) given on days 1 through 5 every 3 weeks in patients with recurrent/ refractory epithelial ovarian cancer. J Clin Oncol 2002;20: 1562-9.
    • (2002) J Clin Oncol , vol.20 , pp. 1562-1569
    • Vasey, P.A.1    Shulman, L.N.2    Campos, S.3
  • 19
    • 20144368516 scopus 로고    scopus 로고
    • Phase I-II trial of ONYX-015 in combination with MAP chemotherapy in patients with advanced sarcomas
    • Galanis E, Okuno SH, Nascimento AG, et al. Phase I-II trial of ONYX-015 in combination with MAP chemotherapy in patients with advanced sarcomas. Gene Ther 2005;12:437-45.
    • (2005) Gene Ther , vol.12 , pp. 437-445
    • Galanis, E.1    Okuno, S.H.2    Nascimento, A.G.3
  • 20
    • 25644442467 scopus 로고    scopus 로고
    • Nanoparticles enhance therapeutic efficiency by selectively increased local drug dose in experimental colitis in rats
    • Lamprecht A, Yamamoto H, Takeuchi H, Kawashima Y. Nanoparticles enhance therapeutic efficiency by selectively increased local drug dose in experimental colitis in rats. J Pharmacol Exp Ther 2005; 315:196-202.
    • (2005) J Pharmacol Exp Ther , vol.315 , pp. 196-202
    • Lamprecht, A.1    Yamamoto, H.2    Takeuchi, H.3    Kawashima, Y.4
  • 21
    • 0022624749 scopus 로고
    • Differential expression of endogenous lectins on the surface of nontumorigenic, tumorigenic, and metastatic cells
    • Raz A, Meromsky L, Lotan R. Differential expression of endogenous lectins on the surface of nontumorigenic, tumorigenic, and metastatic cells. Cancer Res 1986;46:3667-72.
    • (1986) Cancer Res , vol.46 , pp. 3667-3672
    • Raz, A.1    Meromsky, L.2    Lotan, R.3
  • 22
    • 0035740634 scopus 로고    scopus 로고
    • On the role of cell surface carbohydrates and their binding proteins (lectins) in tumor metastasis
    • Gorelik E, Galili U, Raz A. On the role of cell surface carbohydrates and their binding proteins (lectins) in tumor metastasis. Cancer Metastasis Rev 2001;20:245-77.
    • (2001) Cancer Metastasis Rev , vol.20 , pp. 245-277
    • Gorelik, E.1    Galili, U.2    Raz, A.3
  • 23
    • 0034734974 scopus 로고    scopus 로고
    • Endogenous lectins as targets for drug delivery
    • Yamazaki N, Kojima S, Bovin NV, et al. Endogenous lectins as targets for drug delivery. Adv Drug Deliv Rev 2000;43:225-44.
    • (2000) Adv Drug Deliv Rev , vol.43 , pp. 225-244
    • Yamazaki, N.1    Kojima, S.2    Bovin, N.V.3
  • 24
    • 0024147194 scopus 로고
    • How protein toxins enter and kill cells
    • Olsnes S, Sandvig K. How protein toxins enter and kill cells. Cancer Treat Res 1988;37:39-73.
    • (1988) Cancer Treat Res , vol.37 , pp. 39-73
    • Olsnes, S.1    Sandvig, K.2
  • 25
    • 0029934710 scopus 로고    scopus 로고
    • Kinetic analysis of receptor-mediated endocytosis (RME) of proteins and peptides: Use of RME as a drug delivery system
    • Kato Y, Seita T, Kuwabara T. Kinetic analysis of receptor-mediated endocytosis (RME) of proteins and peptides: use of RME as a drug delivery system. J Control Release 1996;39:191-200.
    • (1996) J Control Release , vol.39 , pp. 191-200
    • Kato, Y.1    Seita, T.2    Kuwabara, T.3
  • 26
    • 0025882501 scopus 로고
    • Targeting behavior of rat monoclonal IgG antibodies in vivo: Role of antibody isotype, specificity and the target cell antigen density
    • Yousaf N, Howard JC, Williams BD. Targeting behavior of rat monoclonal IgG antibodies in vivo: role of antibody isotype, specificity and the target cell antigen density. Eur J Immunol 1991;21:943-50.
    • (1991) Eur J Immunol , vol.21 , pp. 943-950
    • Yousaf, N.1    Howard, J.C.2    Williams, B.D.3
  • 28
    • 0025019752 scopus 로고
    • A clinical efficacy of poly(ethylene glycol) - Modified proteins
    • Fuertges F, Abuchowski A. A clinical efficacy of poly(ethylene glycol)- modified proteins. J Control Release 1990;11:139-48.
    • (1990) J Control Release , vol.11 , pp. 139-148
    • Fuertges, F.1    Abuchowski, A.2
  • 29
    • 0035291191 scopus 로고    scopus 로고
    • SMANCS and polymer-conjugated macromolecular drugs: Advantages in cancer chemotherapy
    • Maeda H. SMANCS and polymer-conjugated macromolecular drugs: advantages in cancer chemotherapy. Adv Drug Deliv Rev 2001; 46:169-85.
    • (2001) Adv Drug Deliv Rev , vol.46 , pp. 169-185
    • Maeda, H.1
  • 30
    • 0034026798 scopus 로고    scopus 로고
    • Poly(ethylene glycol) multiblock copolymer as a carrier of anti-cancer drug doxorubicin
    • Pechar M, Ulbrich K, Subr V, Seymour LW, Schacht EH. Poly(ethylene glycol) multiblock copolymer as a carrier of anti-cancer drug doxorubicin. Bioconjug Chem 2000;11:131-9.
    • (2000) Bioconjug Chem , vol.11 , pp. 131-139
    • Pechar, M.1    Ulbrich, K.2    Subr, V.3    Seymour, L.W.4    Schacht, E.H.5
  • 31
    • 0037028050 scopus 로고    scopus 로고
    • Probing the cysteine-34 position of endogenous serum albumin with thiol-binding doxorubicin derivatives: Improved efficacy of an acid-sensitive doxorubicin derivative with specific albumin-binding properties compared with that of the parent compound
    • Kratz F, Warneke A, Scheuermann K, et al. Probing the cysteine-34 position of endogenous serum albumin with thiol-binding doxorubicin derivatives: improved efficacy of an acid-sensitive doxorubicin derivative with specific albumin-binding properties compared with that of the parent compound. J Med Chem 2002;25:5523-33.
    • (2002) J Med Chem , vol.25 , pp. 5523-5533
    • Kratz, F.1    Warneke, A.2    Scheuermann, K.3
  • 32
    • 0342314489 scopus 로고    scopus 로고
    • A novel macromolecular prodrug concept exploiting endogenous serum albumin as a drug carrier for cancer chemotherapy
    • Kratz F, Muller-Driver R, Hofmann I, Drevs J, Unger C. A novel macromolecular prodrug concept exploiting endogenous serum albumin as a drug carrier for cancer chemotherapy. J Med Chem 2000;43:1253-6.
    • (2000) J Med Chem , vol.43 , pp. 1253-1256
    • Kratz, F.1    Muller-Driver, R.2    Hofmann, I.3    Drevs, J.4    Unger, C.5
  • 33
    • 0032959549 scopus 로고    scopus 로고
    • Phase I clinical and pharmacokinetic study of PK1 [N-(2-hydroxypropyl)methacrylamide copolymer doxorubicin): First member of a new class of chemotherapeutic agents-drug-polymer conjugates. Cancer Research Campaign Phase I/II Committee
    • Vasey PA, Kaye SB, Morrison R, et al. Phase I clinical and pharmacokinetic study of PK1 [N-(2-hydroxypropyl)methacrylamide copolymer doxorubicin): first member of a new class of chemotherapeutic agents-drug-polymer conjugates. Cancer Research Campaign Phase I/II Committee. Clin Cancer Res 1999;5:83-94.
    • (1999) Clin Cancer Res , vol.5 , pp. 83-94
    • Vasey, P.A.1    Kaye, S.B.2    Morrison, R.3
  • 34
    • 0022405518 scopus 로고
    • Optimization of macromolecular prodrugs of the antitumor metabolite antibiotic adriamycin
    • Hoes C, Potman, W, Heeswijk V. Optimization of macromolecular prodrugs of the antitumor metabolite antibiotic adriamycin. J Control Release 1985;2:205-13.
    • (1985) J Control Release , vol.2 , pp. 205-213
    • Hoes, C.1    Potman, W.2    Heeswijk, V.3
  • 35
    • 0027390175 scopus 로고
    • Biological properties of adriamycin-bound to biodegradable polymeric carriers
    • Hoes C, Grootoonk J, Duncan R. Biological properties of adriamycin-bound to biodegradable polymeric carriers. J Control Release 1993;23: 37-54.
    • (1993) J Control Release , vol.23 , pp. 37-54
    • Hoes, C.1    Grootoonk, J.2    Duncan, R.3
  • 36
    • 0019170967 scopus 로고
    • Soluble macromolecules as carriers for daunorubicin
    • Huriwitz E, Wilcheck M, Pitha J. Soluble macromolecules as carriers for daunorubicin. J Appl Biochem 1980;2:25-35.
    • (1980) J Appl Biochem , vol.2 , pp. 25-35
    • Huriwitz, E.1    Wilcheck, M.2    Pitha, J.3
  • 37
    • 0021326198 scopus 로고
    • Antitumor activity of 1-β-D-arabinofuranosylcytosine conjugated with polyglutamic acid and its derivative
    • Kato Y, Saito M, Fukushima H, Takeda Y, Hara T. Antitumor activity of 1-β-D-arabinofuranosylcytosine conjugated with polyglutamic acid and its derivative. Cancer Res 1984;44:25-30.
    • (1984) Cancer Res , vol.44 , pp. 25-30
    • Kato, Y.1    Saito, M.2    Fukushima, H.3    Takeda, Y.4    Hara, T.5
  • 38
    • 0000299008 scopus 로고
    • Pharmacologically active polymers. Cyclophosphamide and steroid hormone-containing polymers as potential anti-cancer compounds
    • Batz H, Ringsdorf H, Ritter H. Pharmacologically active polymers. Cyclophosphamide and steroid hormone-containing polymers as potential anti-cancer compounds. Macromol Chem 1975;175:2229-39.
    • (1975) Macromol Chem , vol.175 , pp. 2229-2239
    • Batz, H.1    Ringsdorf, H.2    Ritter, H.3
  • 39
    • 0038387390 scopus 로고    scopus 로고
    • The dawning era of polymer therapeutics
    • Duncan R. The dawning era of polymer therapeutics. Nat Rev Drug Discov 2003;2:347-60.
    • (2003) Nat Rev Drug Discov , vol.2 , pp. 347-360
    • Duncan, R.1
  • 40
    • 0038327602 scopus 로고    scopus 로고
    • In vitro and in vivo antitumor activity of methotrexate conjugated to human serum albumin in human cancer cells
    • Wosikowski K, Biedermann E, Rattel B, et al. In vitro and in vivo antitumor activity of methotrexate conjugated to human serum albumin in human cancer cells. Clin Cancer Res 2003;9:1917-26.
    • (2003) Clin Cancer Res , vol.9 , pp. 1917-1926
    • Wosikowski, K.1    Biedermann, E.2    Rattel, B.3
  • 41
    • 0034177397 scopus 로고    scopus 로고
    • The taxanes: An update
    • Crown J, O'Leary M. The taxanes: an update. Lancet 2000;355: 1176-8.
    • (2000) Lancet , vol.355 , pp. 1176-1178
    • Crown, J.1    O'Leary, M.2
  • 42
    • 0034880214 scopus 로고    scopus 로고
    • Cremophor EL: The drawbacks and advantages of vehicle selection for drug formulation
    • Gelderblom H, Verweij J, Nooter K, Sparreboom A. Cremophor EL: the drawbacks and advantages of vehicle selection for drug formulation. Eur J Cancer 2001;37:1590-8.
    • (2001) Eur J Cancer , vol.37 , pp. 1590-1598
    • Gelderblom, H.1    Verweij, J.2    Nooter, K.3    Sparreboom, A.4
  • 43
    • 0028328762 scopus 로고
    • Potential neurotoxicity of the solvent vehicle for cyclosporine
    • Windebank AJ, Blexrud MD, de Groen PC. Potential neurotoxicity of the solvent vehicle for cyclosporine. J Pharmacol Exp Ther 1994;268: 1051-6.
    • (1994) J Pharmacol Exp Ther , vol.268 , pp. 1051-1056
    • Windebank, A.J.1    Blexrud, M.D.2    de Groen, P.C.3
  • 44
    • 0036096946 scopus 로고    scopus 로고
    • Phase I and pharmacokinetic study of ABI-007, a Cremophor-free, protein-stabilized, nanoparticle formulation of paclitaxel
    • Ibrahim NK, Desai N, Legha S, et al. Phase I and pharmacokinetic study of ABI-007, a Cremophor-free, protein-stabilized, nanoparticle formulation of paclitaxel. Clin Cancer Res 2002;8:1038-44.
    • (2002) Clin Cancer Res , vol.8 , pp. 1038-1044
    • Ibrahim, N.K.1    Desai, N.2    Legha, S.3
  • 45
    • 4043117198 scopus 로고    scopus 로고
    • A phase I trial of ABI-007, nanoparticle paclitaxel, administered to patients with advanced non-hematological malignancies [abstract 2027)]
    • Nyman D, Campbell K, Hersh. A phase I trial of ABI-007, nanoparticle paclitaxel, administered to patients with advanced non-hematological malignancies [abstract 2027)]. Oncol 2004;23:133.
    • (2004) Oncol , vol.23 , pp. 133
    • Nyman, D.1    Campbell, K.2    Hersh3
  • 46
    • 0035889882 scopus 로고    scopus 로고
    • Intraarterial chemotherapy with polyoxyethylated castor oil free paclitaxel, incorporated in albumin nanoparticles (ABI-007): Phase II study of patients with squamous cell carcinoma of the head and neck and anal canal: Preliminary evidence of clinical activity
    • Damascelli B, Cantu G, Mattavelli F, et al. Intraarterial chemotherapy with polyoxyethylated castor oil free paclitaxel, incorporated in albumin nanoparticles (ABI-007): phase II study of patients with squamous cell carcinoma of the head and neck and anal canal: preliminary evidence of clinical activity. Cancer 2001;92:2592-602.
    • (2001) Cancer , vol.92 , pp. 2592-2602
    • Damascelli, B.1    Cantu, G.2    Mattavelli, F.3
  • 47
    • 0035858296 scopus 로고    scopus 로고
    • In vivo evaluation of polymeric micellar paclitaxel formulation: Toxicity and efficacy
    • Kim SC, Kim DW, Shim YH, et al. In vivo evaluation of polymeric micellar paclitaxel formulation: toxicity and efficacy. J Control Release 2001;72:191-202.
    • (2001) J Control Release , vol.72 , pp. 191-202
    • Kim, S.C.1    Kim, D.W.2    Shim, Y.H.3
  • 48
    • 2542559832 scopus 로고    scopus 로고
    • Phase I and pharmacokinetic study of Genexol-PM, a cremophor-free, polymeric micelle-formulated paclitaxel, in patients with advanced malignancies
    • Kim TY, Kim DW, Chung JY, et al. Phase I and pharmacokinetic study of Genexol-PM, a cremophor-free, polymeric micelle-formulated paclitaxel, in patients with advanced malignancies. Clin Cancer Res 2004;10:3708-16.
    • (2004) Clin Cancer Res , vol.10 , pp. 3708-3716
    • Kim, T.Y.1    Kim, D.W.2    Chung, J.Y.3
  • 49
    • 0037619168 scopus 로고    scopus 로고
    • Poly-(L)-glutamic acid-paclitaxel (CT-2103) [XYOTAX], a biodegradable polymeric drug conjugate: Characterization, preclinical pharmacology, and preliminary clinical data
    • Singer JW, Baker B, De Vries P, et al. Poly-(L)-glutamic acid-paclitaxel (CT-2103) [XYOTAX], a biodegradable polymeric drug conjugate: characterization, preclinical pharmacology, and preliminary clinical data. Adv Exp Med Biol 2003;519:81-99.
    • (2003) Adv Exp Med Biol , vol.519 , pp. 81-99
    • Singer, J.W.1    Baker, B.2    De Vries, P.3
  • 50
  • 52
    • 20344397793 scopus 로고    scopus 로고
    • Phase 2 study of CT-2103 in patients with colorectal cancer having recurrent disease after treatment with 5-fluorouracil-containing regimen
    • (Abstract #1137)
    • Schulz J, Burris H, Redfern C, Bolton MG. Phase 2 study of CT-2103 in patients with colorectal cancer having recurrent disease after treatment with 5-fluorouracil-containing regimen. Proc Am Soc Clin Oncol 22: (Abstract #1137), 2003.
    • (2003) Proc Am Soc Clin Oncol , vol.22
    • Schulz, J.1    Burris, H.2    Redfern, C.3    Bolton, M.G.4
  • 53
    • 20344375322 scopus 로고    scopus 로고
    • A phase 2 study of CT-2103, a Poly(L-glutamic acid)-paclitaxel conjugate administered every 3 weeks in patients with advanced breast cancer
    • (Abstract #169)
    • Robson L, Verrill M, Lind MJ, et al. A phase 2 study of CT-2103, a Poly(L-glutamic acid)-paclitaxel conjugate administered every 3 weeks in patients with advanced breast cancer. Proc Am Soc Clin Oncol 22:42 (Abstract #169), 2003.
    • (2003) Proc Am Soc Clin Oncol , vol.22 , pp. 42
    • Robson, L.1    Verrill, M.2    Lind, M.J.3
  • 54
    • 0035213434 scopus 로고    scopus 로고
    • Targeting endothelial cells overexpressing VEGFR-2: Selective toxicity of Shiga-like toxin-VEGF fusion proteins
    • Backer MV, Backer JM. Targeting endothelial cells overexpressing VEGFR-2: selective toxicity of Shiga-like toxin-VEGF fusion proteins. Bioconjug Chem 2001;12:1066-73.
    • (2001) Bioconjug Chem , vol.12 , pp. 1066-1073
    • Backer, M.V.1    Backer, J.M.2
  • 55
    • 0033625094 scopus 로고    scopus 로고
    • Synthesis of [{99m}Tc]DTPA-folate and its evaluation as a folate-receptor-targeted radiopharmaceutical
    • Mathias CJ, Hubers D, Low PS, Green MA. Synthesis of [{99m}Tc]DTPA-folate and its evaluation as a folate-receptor-targeted radiopharmaceutical. Bioconjug Chem 2000;11:253-7.
    • (2000) Bioconjug Chem , vol.11 , pp. 253-257
    • Mathias, C.J.1    Hubers, D.2    Low, P.S.3    Green, M.A.4
  • 56
    • 0037407394 scopus 로고    scopus 로고
    • Targeting doxorubicin to epidermal growth factor receptors by site-specific conjugation of C225 to poly(L-glutamic acid) through a polyethylene glycol spacer
    • Vega J, Ke S, Fan Z, et al. Targeting doxorubicin to epidermal growth factor receptors by site-specific conjugation of C225 to poly(L-glutamic acid) through a polyethylene glycol spacer. Pharm Res 2003;20: 826-32.
    • (2003) Pharm Res , vol.20 , pp. 826-832
    • Vega, J.1    Ke, S.2    Fan, Z.3
  • 57
    • 0016831976 scopus 로고
    • Suppression of tumour growth in mice by a drug-antibody conjugate using a novel approach to linkage
    • Rowland GF, O'Neill GJ, Davies DA. Suppression of tumour growth in mice by a drug-antibody conjugate using a novel approach to linkage. Nature 1975;255:487-8.
    • (1975) Nature , vol.255 , pp. 487-488
    • Rowland, G.F.1    O'Neill, G.J.2    Davies, D.A.3
  • 58
    • 0037087719 scopus 로고    scopus 로고
    • Hepatic drug targeting: Phase I evaluation of polymer-bound doxorubicin
    • Seymour LW, Ferry DR, Anderson D, et al. Hepatic drug targeting: phase I evaluation of polymer-bound doxorubicin. J Clin Oncol 2002;20: 1668-76.
    • (2002) J Clin Oncol , vol.20 , pp. 1668-1676
    • Seymour, L.W.1    Ferry, D.R.2    Anderson, D.3
  • 59
    • 0027406702 scopus 로고
    • Trophoblast and ovarian cancer antigen LK26. Sensitivity and specificity in immunopathology and molecular identification as a folate-binding protein
    • Garin-Chesa P, Campbell I, Saigo PE, et al. Trophoblast and ovarian cancer antigen LK26. Sensitivity and specificity in immunopathology and molecular identification as a folate-binding protein. Am J Pathol 1993; 142:557-67.
    • (1993) Am J Pathol , vol.142 , pp. 557-567
    • Garin-Chesa, P.1    Campbell, I.2    Saigo, P.E.3
  • 60
    • 0032439486 scopus 로고    scopus 로고
    • Folate-mediated targeting of therapeutic and imaging agents to cancers
    • Reddy JA, Low PS. Folate-mediated targeting of therapeutic and imaging agents to cancers. Crit Rev Ther Drug Carrier Syst 1998; 15:587-627.
    • (1998) Crit Rev Ther Drug Carrier Syst , vol.15 , pp. 587-627
    • Reddy, J.A.1    Low, P.S.2
  • 61
    • 0036071884 scopus 로고    scopus 로고
    • Intracellular delivery of nanometric DNA particles via the folate receptor
    • Dauty E, Remy JS, Zuber G, Behr JP. Intracellular delivery of nanometric DNA particles via the folate receptor. Bioconjug Chem 2002; 13:831-9.
    • (2002) Bioconjug Chem , vol.13 , pp. 831-839
    • Dauty, E.1    Remy, J.S.2    Zuber, G.3    Behr, J.P.4
  • 62
    • 8544249119 scopus 로고    scopus 로고
    • Tumor-targeted bioconjugate based delivery of camptothecin: Design, synthesis and in vitro evaluation
    • Paranjpe PV, Chen Y, Kholodovych V, et al. Tumor-targeted bioconjugate based delivery of camptothecin: design, synthesis and in vitro evaluation. J Control Release 2004;100:275-92.
    • (2004) J Control Release , vol.100 , pp. 275-292
    • Paranjpe, P.V.1    Chen, Y.2    Kholodovych, V.3
  • 63
    • 8544219695 scopus 로고    scopus 로고
    • Folate-receptor-targeted delivery of doxorubicin nano-aggregates stabilized by doxorubicin-PEG-folate conjugate
    • Yoo HS, Park TG. Folate-receptor-targeted delivery of doxorubicin nano-aggregates stabilized by doxorubicin-PEG-folate conjugate. J Control Release 2004;100:247-56.
    • (2004) J Control Release , vol.100 , pp. 247-256
    • Yoo, H.S.1    Park, T.G.2
  • 64
    • 11244349115 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) inhibition by small molecules
    • Ahmed SI, Thomas AL, Steward WP. Vascular endothelial growth factor (VEGF) inhibition by small molecules. J Chemother 2004;16 Suppl 4:59-63.
    • (2004) J Chemother , vol.16 , Issue.SUPPL. 4 , pp. 59-63
    • Ahmed, S.I.1    Thomas, A.L.2    Steward, W.P.3
  • 67
    • 0038714289 scopus 로고    scopus 로고
    • Endothelial signaling during development
    • Cleaver O, Melton DA. Endothelial signaling during development. Nat Med 2003;9:661-8.
    • (2003) Nat Med , vol.9 , pp. 661-668
    • Cleaver, O.1    Melton, D.A.2
  • 68
    • 0028049293 scopus 로고
    • Design and synthesis of novel cyclic RGD-containing peptides as highly potent and selective integrin αllbβ3 antagonists
    • Cheng S, Craig WS, Mullen D, et al. Design and synthesis of novel cyclic RGD-containing peptides as highly potent and selective integrin αllbβ3 antagonists. J Med Chem 1994;37:1-8.
    • (1994) J Med Chem , vol.37 , pp. 1-8
    • Cheng, S.1    Craig, W.S.2    Mullen, D.3
  • 69
    • 15044353995 scopus 로고    scopus 로고
    • Pharmacokinetics and biodistribution of RGD-targeted doxorubicin-loaded nanoparticles in tumor-bearing mice
    • Bibby DC, Talmadge JE, Dalal MK, et al. Pharmacokinetics and biodistribution of RGD-targeted doxorubicin-loaded nanoparticles in tumor-bearing mice. Int J Pharm 2005;293:281-90.
    • (2005) Int J Pharm , vol.293 , pp. 281-290
    • Bibby, D.C.1    Talmadge, J.E.2    Dalal, M.K.3


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