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Volumn 143, Issue 2, 2002, Pages 339-342

Minireview: Secondary β-cell failure in type 2 diabetes - A convergence of glucotoxicity and lipotoxicity

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACID; GLUCOSE; INSULIN; TRANSCRIPTION FACTOR; TRIACYLGLYCEROL;

EID: 0036153256     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.143.2.8623     Document Type: Short Survey
Times cited : (668)

References (35)
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  • 11
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    • The reduction of insulin gene transcription in HIT-T15 β cells chronically exposed to high glucose concentration is associated with the loss of RIPE3b1 and STF-1 transcription factor expression
    • (1995) Mol Endocrinol , vol.9 , pp. 1127-1134
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  • 13
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    • Pancreatic β-cell-specific repression of insulin gene transcription by CCAAT/Enhancer-binding protein β. Inhibitory interactions with basic helix-loop-helix transcription factor E47
    • (1997) J Biol Chem , vol.272 , pp. 28349-28359
    • Lu, M.1    Seufert, J.2    Habener, J.F.3
  • 14
    • 0032103208 scopus 로고    scopus 로고
    • Differential expression of the insulin gene transcriptional repressor CCAAT/enhancer-binding protein beta and transactivator islet duodenum homeobox-1 in rat pancreatic β cells during the development of diabetes mellitus
    • (1998) J Clin Invest , vol.101 , pp. 2528-2539
    • Seufert, J.1    Weir, G.C.2    Habener, J.F.3
  • 16
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    • Long term effects of aminoguanidine on insulin release and biosynthesis: Evidence that the formation of advanced glycosylation end products inhibits β-cell function
    • (1997) Endocrinology , vol.138 , pp. 273-280
    • Tajiri, Y.1    Moller, C.2    Grill, V.3
  • 29
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    • Are the β-cell signaling molecules malonyl-CoA and cytosolic long-chain acyl-CoA implicated in multiple tissue defects of obesity and NIDDM?
    • (1996) Diabetes , vol.45 , pp. 273-283
    • Prentki, M.1    Corkey, B.E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.