-
2
-
-
5044238876
-
Integrin signalling during tumour progression
-
Guo W., and Giancotti F.G. Integrin signalling during tumour progression. Nature Reviews 5 (2004) 816-826
-
(2004)
Nature Reviews
, vol.5
, pp. 816-826
-
-
Guo, W.1
Giancotti, F.G.2
-
4
-
-
0037509990
-
Focal adhesion kinase: the first ten years
-
Parsons J.T. Focal adhesion kinase: the first ten years. Journal of Cell Science 116 (2003) 1409-1416
-
(2003)
Journal of Cell Science
, vol.116
, pp. 1409-1416
-
-
Parsons, J.T.1
-
5
-
-
24344508125
-
Src and FAK kinases cooperate to phosphorylate paxillin kinase linker, stimulate its focal adhesion localization, and regulate cell spreading and protrusiveness
-
Brown M.C., Cary L.A., Jamieson J.S., Cooper J.A., and Turner C.E. Src and FAK kinases cooperate to phosphorylate paxillin kinase linker, stimulate its focal adhesion localization, and regulate cell spreading and protrusiveness. Molecular Biology of the Cell 16 (2005) 4316-4328
-
(2005)
Molecular Biology of the Cell
, vol.16
, pp. 4316-4328
-
-
Brown, M.C.1
Cary, L.A.2
Jamieson, J.S.3
Cooper, J.A.4
Turner, C.E.5
-
6
-
-
0030694182
-
Inhibition of cell spreading by expression of the C-terminal domain of focal adhesion kinase (FAK) is rescued by coexpression of Src or catalytically inactive FAK: a role for paxillin tyrosine phosphorylation
-
Richardson A., Malik R.K., Hildebrand J.D., and Parsons J.T. Inhibition of cell spreading by expression of the C-terminal domain of focal adhesion kinase (FAK) is rescued by coexpression of Src or catalytically inactive FAK: a role for paxillin tyrosine phosphorylation. Molecular and Cellular Biology 17 (1997) 6906-6914
-
(1997)
Molecular and Cellular Biology
, vol.17
, pp. 6906-6914
-
-
Richardson, A.1
Malik, R.K.2
Hildebrand, J.D.3
Parsons, J.T.4
-
7
-
-
33749464239
-
Initiation of attachment and generation of mature focal adhesions by integrin-containing filopodia in cell spreading
-
Partridge M.A., and Marcantonio E.E. Initiation of attachment and generation of mature focal adhesions by integrin-containing filopodia in cell spreading. Molecular Biology of the Cell 17 (2006) 4237-4248
-
(2006)
Molecular Biology of the Cell
, vol.17
, pp. 4237-4248
-
-
Partridge, M.A.1
Marcantonio, E.E.2
-
8
-
-
34249798185
-
FAK association with multiple signal proteins mediates pressure-induced colon cancer cell adhesion via a Src-dependent PI3K/Akt pathway
-
Thamilselvan V., Craig D.H., and Basson M.D. FAK association with multiple signal proteins mediates pressure-induced colon cancer cell adhesion via a Src-dependent PI3K/Akt pathway. FASEB Journal 21 (2007) 1730-1741
-
(2007)
FASEB Journal
, vol.21
, pp. 1730-1741
-
-
Thamilselvan, V.1
Craig, D.H.2
Basson, M.D.3
-
9
-
-
0033581873
-
Requirement for focal adhesion kinase in tumor cell adhesion
-
Maung K., Easty D.J., Hill S.P., and Bennett D.C. Requirement for focal adhesion kinase in tumor cell adhesion. Oncogene 18 (1999) 6824-6828
-
(1999)
Oncogene
, vol.18
, pp. 6824-6828
-
-
Maung, K.1
Easty, D.J.2
Hill, S.P.3
Bennett, D.C.4
-
10
-
-
0027055575
-
Cell adhesion or integrin clustering increases phosphorylation of a focal adhesion-associated tyrosine kinase
-
Kornberg L., Earp H.S., Parsons J.T., Schaller M., and Juliano R.L. Cell adhesion or integrin clustering increases phosphorylation of a focal adhesion-associated tyrosine kinase. The Journal of Biological Chemistry 267 (1992) 23439-23442
-
(1992)
The Journal of Biological Chemistry
, vol.267
, pp. 23439-23442
-
-
Kornberg, L.1
Earp, H.S.2
Parsons, J.T.3
Schaller, M.4
Juliano, R.L.5
-
11
-
-
0026445719
-
Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly
-
Burridge K., Turner C.E., and Romer L.H. Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly. The Journal of Cell Biology 119 (1992) 893-903
-
(1992)
The Journal of Cell Biology
, vol.119
, pp. 893-903
-
-
Burridge, K.1
Turner, C.E.2
Romer, L.H.3
-
12
-
-
13244286648
-
Focal adhesion kinase regulates metastatic adhesion of carcinoma cells within liver sinusoids
-
von Sengbusch A., Gassmann P., Fisch K.M., Enns A., Nicolson G.L., and Haier J. Focal adhesion kinase regulates metastatic adhesion of carcinoma cells within liver sinusoids. The American Journal of Pathology 166 (2005) 585-596
-
(2005)
The American Journal of Pathology
, vol.166
, pp. 585-596
-
-
von Sengbusch, A.1
Gassmann, P.2
Fisch, K.M.3
Enns, A.4
Nicolson, G.L.5
Haier, J.6
-
13
-
-
0033002997
-
Induced focal adhesion kinase (FAK) expression in FAK-null cells enhances cell spreading and migration requiring both auto- and activation loop phosphorylation sites and inhibits adhesion-dependent tyrosine phosphorylation of Pyk2
-
Owen J.D., Ruest P.J., Fry D.W., and Hanks S.K. Induced focal adhesion kinase (FAK) expression in FAK-null cells enhances cell spreading and migration requiring both auto- and activation loop phosphorylation sites and inhibits adhesion-dependent tyrosine phosphorylation of Pyk2. Molecular and Cellular Biology 19 (1999) 4806-4818
-
(1999)
Molecular and Cellular Biology
, vol.19
, pp. 4806-4818
-
-
Owen, J.D.1
Ruest, P.J.2
Fry, D.W.3
Hanks, S.K.4
-
14
-
-
0029948080
-
Stimulation of cell migration by overexpression of focal adhesion kinase and its association with Src and Fyn
-
Cary L.A., Chang J.F., and Guan J.L. Stimulation of cell migration by overexpression of focal adhesion kinase and its association with Src and Fyn. Journal of Cell Science 109 Pt 7 (1996) 1787-1794
-
(1996)
Journal of Cell Science
, vol.109
, Issue.PART 7
, pp. 1787-1794
-
-
Cary, L.A.1
Chang, J.F.2
Guan, J.L.3
-
15
-
-
0028018234
-
Potential role for focal adhesion kinase in migrating and proliferating keratinocytes near epidermal wounds and in culture
-
Gates R.E., King Jr. L.E., Hanks S.K., and Nanney L.B. Potential role for focal adhesion kinase in migrating and proliferating keratinocytes near epidermal wounds and in culture. Cell Growth and Differentiation 5 (1994) 891-899
-
(1994)
Cell Growth and Differentiation
, vol.5
, pp. 891-899
-
-
Gates, R.E.1
King Jr., L.E.2
Hanks, S.K.3
Nanney, L.B.4
-
16
-
-
0029120440
-
Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice
-
Ilic D., Furuta Y., Kanazawa S., Takeda N., Sobue K., Nakatsuji N., Nomura S., Fujimoto J., Okada M., and Yamamoto T. Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice. Nature 377 (1995) 539-544
-
(1995)
Nature
, vol.377
, pp. 539-544
-
-
Ilic, D.1
Furuta, Y.2
Kanazawa, S.3
Takeda, N.4
Sobue, K.5
Nakatsuji, N.6
Nomura, S.7
Fujimoto, J.8
Okada, M.9
Yamamoto, T.10
-
17
-
-
0032820782
-
Required role of focal adhesion kinase (FAK) for integrin-stimulated cell migration
-
Sieg D.J., Hauck C.R., and Schlaepfer D.D. Required role of focal adhesion kinase (FAK) for integrin-stimulated cell migration. Journal of Cell Science 112 Pt 16 (1999) 2677-2691
-
(1999)
Journal of Cell Science
, vol.112
, Issue.PART 16
, pp. 2677-2691
-
-
Sieg, D.J.1
Hauck, C.R.2
Schlaepfer, D.D.3
-
18
-
-
3142521875
-
Control of motile and invasive cell phenotypes by focal adhesion kinase
-
Schlaepfer D.D., Mitra S.K., and Ilic D. Control of motile and invasive cell phenotypes by focal adhesion kinase. Biochimica et Biophysica Acta 1692 (2004) 77-102
-
(2004)
Biochimica et Biophysica Acta
, vol.1692
, pp. 77-102
-
-
Schlaepfer, D.D.1
Mitra, S.K.2
Ilic, D.3
-
19
-
-
0037011055
-
FRNK blocks v-Src-stimulated invasion and experimental metastases without effects on cell motility or growth
-
Hauck C.R., Hsia D.A., Puente X.S., Cheresh D.A., and Schlaepfer D.D. FRNK blocks v-Src-stimulated invasion and experimental metastases without effects on cell motility or growth. The EMBO Journal 21 (2002) 6289-6302
-
(2002)
The EMBO Journal
, vol.21
, pp. 6289-6302
-
-
Hauck, C.R.1
Hsia, D.A.2
Puente, X.S.3
Cheresh, D.A.4
Schlaepfer, D.D.5
-
20
-
-
0037416174
-
Differential regulation of cell motility and invasion by FAK
-
Hsia D.A., Mitra S.K., Hauck C.R., Streblow D.N., Nelson J.A., Ilic D., Huang S., Li E., Nemerow G.R., Leng J., Spencer K.S., Cheresh D.A., and Schlaepfer D.D. Differential regulation of cell motility and invasion by FAK. The Journal of Cell Biology 160 (2003) 753-767
-
(2003)
The Journal of Cell Biology
, vol.160
, pp. 753-767
-
-
Hsia, D.A.1
Mitra, S.K.2
Hauck, C.R.3
Streblow, D.N.4
Nelson, J.A.5
Ilic, D.6
Huang, S.7
Li, E.8
Nemerow, G.R.9
Leng, J.10
Spencer, K.S.11
Cheresh, D.A.12
Schlaepfer, D.D.13
-
22
-
-
4444338326
-
SRC-mediated phosphorylation of focal adhesion kinase couples actin and adhesion dynamics to survival signaling
-
Westhoff M.A., Serrels B., Fincham V.J., Frame M.C., and Carragher N.O. SRC-mediated phosphorylation of focal adhesion kinase couples actin and adhesion dynamics to survival signaling. Molecular and Cellular Biology 24 (2004) 8113-8133
-
(2004)
Molecular and Cellular Biology
, vol.24
, pp. 8113-8133
-
-
Westhoff, M.A.1
Serrels, B.2
Fincham, V.J.3
Frame, M.C.4
Carragher, N.O.5
-
23
-
-
0035965234
-
Suppression of chemically induced apoptosis but not necrosis of renal proximal tubular epithelial (LLC-PK1) cells by focal adhesion kinase (FAK). Role of FAK in maintaining focal adhesion organization after acute renal cell injury
-
van de Water B., Houtepen F., Huigsloot M., and Tijdens I.B. Suppression of chemically induced apoptosis but not necrosis of renal proximal tubular epithelial (LLC-PK1) cells by focal adhesion kinase (FAK). Role of FAK in maintaining focal adhesion organization after acute renal cell injury. The Journal of Biological Chemistry 276 (2001) 36183-36193
-
(2001)
The Journal of Biological Chemistry
, vol.276
, pp. 36183-36193
-
-
van de Water, B.1
Houtepen, F.2
Huigsloot, M.3
Tijdens, I.B.4
-
24
-
-
0032547796
-
Extracellular matrix survival signals transduced by focal adhesion kinase suppress p53-mediated apoptosis
-
Ilic D., Almeida E.A., Schlaepfer D.D., Dazin P., Aizawa S., and Damsky C.H. Extracellular matrix survival signals transduced by focal adhesion kinase suppress p53-mediated apoptosis. The Journal of Cell Biology 143 (1998) 547-560
-
(1998)
The Journal of Cell Biology
, vol.143
, pp. 547-560
-
-
Ilic, D.1
Almeida, E.A.2
Schlaepfer, D.D.3
Dazin, P.4
Aizawa, S.5
Damsky, C.H.6
-
26
-
-
0030300180
-
Inhibition of pp125FAK in cultured fibroblasts results in apoptosis
-
Hungerford J.E., Compton M.T., Matter M.L., Hoffstrom B.G., and Otey C.A. Inhibition of pp125FAK in cultured fibroblasts results in apoptosis. The Journal of Cell Biology 135 (1996) 1383-1390
-
(1996)
The Journal of Cell Biology
, vol.135
, pp. 1383-1390
-
-
Hungerford, J.E.1
Compton, M.T.2
Matter, M.L.3
Hoffstrom, B.G.4
Otey, C.A.5
-
27
-
-
0034730632
-
The focal adhesion kinase suppresses transformation-associated, anchorage-independent apoptosis in human breast cancer cells. Involvement of death receptor-related signaling pathways
-
Xu L.H., Yang X., Bradham C.A., Brenner D.A., Baldwin Jr. A.S., Craven R.J., and Cance W.G. The focal adhesion kinase suppresses transformation-associated, anchorage-independent apoptosis in human breast cancer cells. Involvement of death receptor-related signaling pathways. The Journal of Biological Chemistry 275 (2000) 30597-30604
-
(2000)
The Journal of Biological Chemistry
, vol.275
, pp. 30597-30604
-
-
Xu, L.H.1
Yang, X.2
Bradham, C.A.3
Brenner, D.A.4
Baldwin Jr., A.S.5
Craven, R.J.6
Cance, W.G.7
-
28
-
-
2342627918
-
Focal adhesion kinase gene silencing promotes anoikis and suppresses metastasis of human pancreatic adenocarcinoma cells
-
Duxbury M.S., Ito H., Zinner M.J., Ashley S.W., and Whang E.E. Focal adhesion kinase gene silencing promotes anoikis and suppresses metastasis of human pancreatic adenocarcinoma cells. Surgery 135 (2004) 555-562
-
(2004)
Surgery
, vol.135
, pp. 555-562
-
-
Duxbury, M.S.1
Ito, H.2
Zinner, M.J.3
Ashley, S.W.4
Whang, E.E.5
-
29
-
-
29944436856
-
Endothelial FAK is essential for vascular network stability, cell survival, and lamellipodial formation
-
Braren R., Hu H., Kim Y.H., Beggs H.E., Reichardt L.F., and Wang R. Endothelial FAK is essential for vascular network stability, cell survival, and lamellipodial formation. The Journal of Cell Biology 172 (2006) 151-162
-
(2006)
The Journal of Cell Biology
, vol.172
, pp. 151-162
-
-
Braren, R.1
Hu, H.2
Kim, Y.H.3
Beggs, H.E.4
Reichardt, L.F.5
Wang, R.6
-
30
-
-
0034532347
-
p125 focal adhesion kinase promotes malignant astrocytoma cell proliferation in vivo
-
Wang D., Grammer J.R., Cobbs C.S., Stewart Jr. J.E., Liu Z., Rhoden R., Hecker T.P., Ding Q., and Gladson C.L. p125 focal adhesion kinase promotes malignant astrocytoma cell proliferation in vivo. Journal of Cell Science 113 Pt 23 (2000) 4221-4230
-
(2000)
Journal of Cell Science
, vol.113
, Issue.PART 23
, pp. 4221-4230
-
-
Wang, D.1
Grammer, J.R.2
Cobbs, C.S.3
Stewart Jr., J.E.4
Liu, Z.5
Rhoden, R.6
Hecker, T.P.7
Ding, Q.8
Gladson, C.L.9
-
31
-
-
0032576547
-
Regulation of the cell cycle by focal adhesion kinase
-
Zhao J.H., Reiske H., and Guan J.L. Regulation of the cell cycle by focal adhesion kinase. The Journal of Cell Biology 143 (1998) 1997-2008
-
(1998)
The Journal of Cell Biology
, vol.143
, pp. 1997-2008
-
-
Zhao, J.H.1
Reiske, H.2
Guan, J.L.3
-
32
-
-
0033612572
-
Integrin-mediated activation of focal adhesion kinase is required for signaling to Jun NH2-terminal kinase and progression through the G1 phase of the cell cycle
-
Oktay M., Wary K.K., Dans M., Birge R.B., and Giancotti F.G. Integrin-mediated activation of focal adhesion kinase is required for signaling to Jun NH2-terminal kinase and progression through the G1 phase of the cell cycle. The Journal of Cell Biology 145 (1999) 1461-1469
-
(1999)
The Journal of Cell Biology
, vol.145
, pp. 1461-1469
-
-
Oktay, M.1
Wary, K.K.2
Dans, M.3
Birge, R.B.4
Giancotti, F.G.5
-
33
-
-
0035661624
-
Transcriptional activation of cyclin D1 promoter by FAK contributes to cell cycle progression
-
Zhao J., Pestell R., and Guan J.L. Transcriptional activation of cyclin D1 promoter by FAK contributes to cell cycle progression. Molecular Biology of the Cell 12 (2001) 4066-4077
-
(2001)
Molecular Biology of the Cell
, vol.12
, pp. 4066-4077
-
-
Zhao, J.1
Pestell, R.2
Guan, J.L.3
-
34
-
-
35748981202
-
Mammary epithelial-specific deletion of the focal adhesion kinase gene leads to severe lobulo-alveolar hypoplasia and secretory immaturity of the murine mammary gland
-
Nagy T., Wei H., Shen T.L., Peng X., Liang C.C., Gan B., and Guan J.L. Mammary epithelial-specific deletion of the focal adhesion kinase gene leads to severe lobulo-alveolar hypoplasia and secretory immaturity of the murine mammary gland. The Journal of Biological Chemistry 282 (2007) 31766-31776
-
(2007)
The Journal of Biological Chemistry
, vol.282
, pp. 31766-31776
-
-
Nagy, T.1
Wei, H.2
Shen, T.L.3
Peng, X.4
Liang, C.C.5
Gan, B.6
Guan, J.L.7
-
35
-
-
8644263977
-
Overexpression of focal adhesion kinase in vascular endothelial cells promotes angiogenesis in transgenic mice
-
Peng X., Ueda H., Zhou H., Stokol T., Shen T.L., Alcaraz A., Nagy T., Vassalli J.D., and Guan J.L. Overexpression of focal adhesion kinase in vascular endothelial cells promotes angiogenesis in transgenic mice. Cardiovascular Research 64 (2004) 421-430
-
(2004)
Cardiovascular Research
, vol.64
, pp. 421-430
-
-
Peng, X.1
Ueda, H.2
Zhou, H.3
Stokol, T.4
Shen, T.L.5
Alcaraz, A.6
Nagy, T.7
Vassalli, J.D.8
Guan, J.L.9
-
36
-
-
22344434300
-
Conditional knockout of focal adhesion kinase in endothelial cells reveals its role in angiogenesis and vascular development in late embryogenesis
-
Shen T.L., Park A.Y., Alcaraz A., Peng X., Jang I., Koni P., Flavell R.A., Gu H., and Guan J.L. Conditional knockout of focal adhesion kinase in endothelial cells reveals its role in angiogenesis and vascular development in late embryogenesis. The Journal of Cell Biology 169 (2005) 941-952
-
(2005)
The Journal of Cell Biology
, vol.169
, pp. 941-952
-
-
Shen, T.L.1
Park, A.Y.2
Alcaraz, A.3
Peng, X.4
Jang, I.5
Koni, P.6
Flavell, R.A.7
Gu, H.8
Guan, J.L.9
-
37
-
-
0026612521
-
pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions
-
Schaller M.D., Borgman C.A., Cobb B.S., Vines R.R., Reynolds A.B., and Parsons J.T. pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions. Proceedings of the National Academy of Sciences of the United States of America 89 (1992) 5192-5196
-
(1992)
Proceedings of the National Academy of Sciences of the United States of America
, vol.89
, pp. 5192-5196
-
-
Schaller, M.D.1
Borgman, C.A.2
Cobb, B.S.3
Vines, R.R.4
Reynolds, A.B.5
Parsons, J.T.6
-
38
-
-
0026249489
-
Fibronectin/integrin interaction induces tyrosine phosphorylation of a 120-kDa protein
-
Guan J.L., Trevithick J.E., and Hynes R.O. Fibronectin/integrin interaction induces tyrosine phosphorylation of a 120-kDa protein. Cell Regulation 2 (1991) 951-964
-
(1991)
Cell Regulation
, vol.2
, pp. 951-964
-
-
Guan, J.L.1
Trevithick, J.E.2
Hynes, R.O.3
-
39
-
-
0026759309
-
Regulation of focal adhesion-associated protein tyrosine kinase by both cellular adhesion and oncogenic transformation
-
Guan J.L., and Shalloway D. Regulation of focal adhesion-associated protein tyrosine kinase by both cellular adhesion and oncogenic transformation. Nature 358 (1992) 690-692
-
(1992)
Nature
, vol.358
, pp. 690-692
-
-
Guan, J.L.1
Shalloway, D.2
-
40
-
-
0033772308
-
FAK integrates growth-factor and integrin signals to promote cell migration
-
Sieg D.J., Hauck C.R., Ilic D., Klingbeil C.K., Schaefer E., Damsky C.H., and Schlaepfer D.D. FAK integrates growth-factor and integrin signals to promote cell migration. Nature Cell Biology 2 (2000) 249-256
-
(2000)
Nature Cell Biology
, vol.2
, pp. 249-256
-
-
Sieg, D.J.1
Hauck, C.R.2
Ilic, D.3
Klingbeil, C.K.4
Schaefer, E.5
Damsky, C.H.6
Schlaepfer, D.D.7
-
41
-
-
0028053831
-
Hepatocyte growth factor/scatter factor induces tyrosine phosphorylation of focal adhesion kinase (p125FAK) and promotes migration and invasion by oral squamous cell carcinoma cells
-
Matsumoto K., Matsumoto K., Nakamura T., and Kramer R.H. Hepatocyte growth factor/scatter factor induces tyrosine phosphorylation of focal adhesion kinase (p125FAK) and promotes migration and invasion by oral squamous cell carcinoma cells. The Journal of Biological Chemistry 269 (1994) 31807-31813
-
(1994)
The Journal of Biological Chemistry
, vol.269
, pp. 31807-31813
-
-
Matsumoto, K.1
Matsumoto, K.2
Nakamura, T.3
Kramer, R.H.4
-
42
-
-
34547126687
-
Tumor necrosis factor-alpha stimulates focal adhesion kinase activity required for mitogen-activated kinase-associated interleukin 6 expression
-
Schlaepfer D.D., Hou S., Lim S.T., Tomar A., Yu H., Lim Y., Hanson D.A., Uryu S.A., Molina J., and Mitra S.K. Tumor necrosis factor-alpha stimulates focal adhesion kinase activity required for mitogen-activated kinase-associated interleukin 6 expression. The Journal of Biological Chemistry 282 (2007) 17450-17459
-
(2007)
The Journal of Biological Chemistry
, vol.282
, pp. 17450-17459
-
-
Schlaepfer, D.D.1
Hou, S.2
Lim, S.T.3
Tomar, A.4
Yu, H.5
Lim, Y.6
Hanson, D.A.7
Uryu, S.A.8
Molina, J.9
Mitra, S.K.10
-
43
-
-
21244494930
-
G protein-coupled receptor activation rapidly stimulates focal adhesion kinase phosphorylation at Ser-843. Mediation by Ca2+, calmodulin, and Ca2+/calmodulin-dependent kinase II
-
Fan R.S., Jacamo R.O., Jiang X., Sinnett-Smith J., and Rozengurt E. G protein-coupled receptor activation rapidly stimulates focal adhesion kinase phosphorylation at Ser-843. Mediation by Ca2+, calmodulin, and Ca2+/calmodulin-dependent kinase II. The Journal of Biological Chemistry 280 (2005) 24212-24220
-
(2005)
The Journal of Biological Chemistry
, vol.280
, pp. 24212-24220
-
-
Fan, R.S.1
Jacamo, R.O.2
Jiang, X.3
Sinnett-Smith, J.4
Rozengurt, E.5
-
44
-
-
0028172435
-
Sphingosine induces p125FAK and paxillin tyrosine phosphorylation, actin stress fiber formation, and focal contact assembly in Swiss 3T3 cells
-
Seufferlein T., and Rozengurt E. Sphingosine induces p125FAK and paxillin tyrosine phosphorylation, actin stress fiber formation, and focal contact assembly in Swiss 3T3 cells. The Journal of Biological Chemistry 269 (1994) 27610-27617
-
(1994)
The Journal of Biological Chemistry
, vol.269
, pp. 27610-27617
-
-
Seufferlein, T.1
Rozengurt, E.2
-
45
-
-
54149118166
-
Arachidonic acid promotes FAK activation and migration in MDA-MB-231 breast cancer cells
-
Navarro-Tito N., Robledo T., and Salazar E.P. Arachidonic acid promotes FAK activation and migration in MDA-MB-231 breast cancer cells. Experimental Cell Research 314 (2008) 3340-3355
-
(2008)
Experimental Cell Research
, vol.314
, pp. 3340-3355
-
-
Navarro-Tito, N.1
Robledo, T.2
Salazar, E.P.3
-
46
-
-
0028350859
-
Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src
-
Schaller M.D., Hildebrand J.D., Shannon J.D., Fox J.W., Vines R.R., and Parsons J.T. Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src. Molecular and Cellular Biology 14 (1994) 1680-1688
-
(1994)
Molecular and Cellular Biology
, vol.14
, pp. 1680-1688
-
-
Schaller, M.D.1
Hildebrand, J.D.2
Shannon, J.D.3
Fox, J.W.4
Vines, R.R.5
Parsons, J.T.6
-
47
-
-
0028342938
-
Direct interaction of v-Src with the focal adhesion kinase mediated by the Src SH2 domain
-
Xing Z., Chen H.C., Nowlen J.K., Taylor S.J., Shalloway D., and Guan J.L. Direct interaction of v-Src with the focal adhesion kinase mediated by the Src SH2 domain. Molecular Biology of the Cell 5 (1994) 413-421
-
(1994)
Molecular Biology of the Cell
, vol.5
, pp. 413-421
-
-
Xing, Z.1
Chen, H.C.2
Nowlen, J.K.3
Taylor, S.J.4
Shalloway, D.5
Guan, J.L.6
-
49
-
-
0029979722
-
Phosphorylation of tyrosine 397 in focal adhesion kinase is required for binding phosphatidylinositol 3-kinase
-
Chen H.C., Appeddu P.A., Isoda H., and Guan J.L. Phosphorylation of tyrosine 397 in focal adhesion kinase is required for binding phosphatidylinositol 3-kinase. The Journal of Biological Chemistry 271 (1996) 26329-26334
-
(1996)
The Journal of Biological Chemistry
, vol.271
, pp. 26329-26334
-
-
Chen, H.C.1
Appeddu, P.A.2
Isoda, H.3
Guan, J.L.4
-
50
-
-
0000226650
-
Association of focal adhesion kinase with Grb7 and its role in cell migration
-
Han D.C., and Guan J.L. Association of focal adhesion kinase with Grb7 and its role in cell migration. The Journal of Biological Chemistry 274 (1999) 24425-24430
-
(1999)
The Journal of Biological Chemistry
, vol.274
, pp. 24425-24430
-
-
Han, D.C.1
Guan, J.L.2
-
51
-
-
0034666146
-
Role of Grb7 targeting to focal contacts and its phosphorylation by focal adhesion kinase in regulation of cell migration
-
Han D.C., Shen T.L., and Guan J.L. Role of Grb7 targeting to focal contacts and its phosphorylation by focal adhesion kinase in regulation of cell migration. The Journal of Biological Chemistry 275 (2000) 28911-28917
-
(2000)
The Journal of Biological Chemistry
, vol.275
, pp. 28911-28917
-
-
Han, D.C.1
Shen, T.L.2
Guan, J.L.3
-
52
-
-
0034711221
-
Distinct roles of the adaptor protein Shc and focal adhesion kinase in integrin signaling to ERK
-
Barberis L., Wary K.K., Fiucci G., Liu F., Hirsch E., Brancaccio M., Altruda F., Tarone G., and Giancotti F.G. Distinct roles of the adaptor protein Shc and focal adhesion kinase in integrin signaling to ERK. The Journal of Biological Chemistry 275 (2000) 36532-36540
-
(2000)
The Journal of Biological Chemistry
, vol.275
, pp. 36532-36540
-
-
Barberis, L.1
Wary, K.K.2
Fiucci, G.3
Liu, F.4
Hirsch, E.5
Brancaccio, M.6
Altruda, F.7
Tarone, G.8
Giancotti, F.G.9
-
53
-
-
0031042108
-
Focal adhesion kinase and phospholipase C gamma involvement in adhesion and migration of human hepatic stellate cells
-
Carloni V., Romanelli R.G., Pinzani M., Laffi G., and Gentilini P. Focal adhesion kinase and phospholipase C gamma involvement in adhesion and migration of human hepatic stellate cells. Gastroenterology 112 (1997) 522-531
-
(1997)
Gastroenterology
, vol.112
, pp. 522-531
-
-
Carloni, V.1
Romanelli, R.G.2
Pinzani, M.3
Laffi, G.4
Gentilini, P.5
-
54
-
-
0033529825
-
Focal adhesion kinase promotes phospholipase C-gamma1 activity
-
Zhang X., Chattopadhyay A., Ji Q.S., Owen J.D., Ruest P.J., Carpenter G., and Hanks S.K. Focal adhesion kinase promotes phospholipase C-gamma1 activity. Proceedings of the National Academy of Sciences of the United States of America 96 (1999) 9021-9026
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, pp. 9021-9026
-
-
Zhang, X.1
Chattopadhyay, A.2
Ji, Q.S.3
Owen, J.D.4
Ruest, P.J.5
Carpenter, G.6
Hanks, S.K.7
-
55
-
-
0028877919
-
Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases
-
Calalb M.B., Polte T.R., and Hanks S.K. Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases. Molecular and Cellular Biology 15 (1995) 954-963
-
(1995)
Molecular and Cellular Biology
, vol.15
, pp. 954-963
-
-
Calalb, M.B.1
Polte, T.R.2
Hanks, S.K.3
-
56
-
-
0036544562
-
Src-mediated coupling of focal adhesion kinase to integrin alpha(v)beta5 in vascular endothelial growth factor signaling
-
Eliceiri B.P., Puente X.S., Hood J.D., Stupack D.G., Schlaepfer D.D., Huang X.Z., Sheppard D., and Cheresh D.A. Src-mediated coupling of focal adhesion kinase to integrin alpha(v)beta5 in vascular endothelial growth factor signaling. The Journal of Cell Biology 157 (2002) 149-160
-
(2002)
The Journal of Cell Biology
, vol.157
, pp. 149-160
-
-
Eliceiri, B.P.1
Puente, X.S.2
Hood, J.D.3
Stupack, D.G.4
Schlaepfer, D.D.5
Huang, X.Z.6
Sheppard, D.7
Cheresh, D.A.8
-
57
-
-
0028609382
-
Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase
-
Schlaepfer D.D., Hanks S.K., Hunter T., and van der Geer P. Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase. Nature 372 (1994) 786-791
-
(1994)
Nature
, vol.372
, pp. 786-791
-
-
Schlaepfer, D.D.1
Hanks, S.K.2
Hunter, T.3
van der Geer, P.4
-
59
-
-
0029955660
-
An SH3 domain-containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinase
-
Hildebrand J.D., Taylor J.M., and Parsons J.T. An SH3 domain-containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinase. Molecular and Cellular Biology 16 (1996) 3169-3178
-
(1996)
Molecular and Cellular Biology
, vol.16
, pp. 3169-3178
-
-
Hildebrand, J.D.1
Taylor, J.M.2
Parsons, J.T.3
-
60
-
-
0035985220
-
The association of ASAP1, an ADP ribosylation factor-GTPase activating protein, with focal adhesion kinase contributes to the process of focal adhesion assembly
-
Liu Y., Loijens J.C., Martin K.H., Karginov A.V., and Parsons J.T. The association of ASAP1, an ADP ribosylation factor-GTPase activating protein, with focal adhesion kinase contributes to the process of focal adhesion assembly. Molecular Biology of the Cell 13 (2002) 2147-2156
-
(2002)
Molecular Biology of the Cell
, vol.13
, pp. 2147-2156
-
-
Liu, Y.1
Loijens, J.C.2
Martin, K.H.3
Karginov, A.V.4
Parsons, J.T.5
-
61
-
-
22944438407
-
FAK-mediated src phosphorylation of endophilin A2 inhibits endocytosis of MT1-MMP and promotes ECM degradation
-
Wu X., Gan B., Yoo Y., and Guan J.L. FAK-mediated src phosphorylation of endophilin A2 inhibits endocytosis of MT1-MMP and promotes ECM degradation. Developmental Cell 9 (2005) 185-196
-
(2005)
Developmental Cell
, vol.9
, pp. 185-196
-
-
Wu, X.1
Gan, B.2
Yoo, Y.3
Guan, J.L.4
-
62
-
-
0028889810
-
Tyrosine phosphorylation and activation of focal adhesion kinase (p125FAK) by BCR-ABL oncoprotein
-
Gotoh A., Miyazawa K., Ohyashiki K., Tauchi T., Boswell H.S., Broxmeyer H.E., and Toyama K. Tyrosine phosphorylation and activation of focal adhesion kinase (p125FAK) by BCR-ABL oncoprotein. Experimental Hematology 23 (1995) 1153-1159
-
(1995)
Experimental Hematology
, vol.23
, pp. 1153-1159
-
-
Gotoh, A.1
Miyazawa, K.2
Ohyashiki, K.3
Tauchi, T.4
Boswell, H.S.5
Broxmeyer, H.E.6
Toyama, K.7
-
63
-
-
0036787909
-
v-Crk activates the phosphoinositide 3-kinase/AKT pathway by utilizing focal adhesion kinase and H-Ras
-
Akagi T., Murata K., Shishido T., and Hanafusa H. v-Crk activates the phosphoinositide 3-kinase/AKT pathway by utilizing focal adhesion kinase and H-Ras. Molecular and Cellular Biology 22 (2002) 7015-7023
-
(2002)
Molecular and Cellular Biology
, vol.22
, pp. 7015-7023
-
-
Akagi, T.1
Murata, K.2
Shishido, T.3
Hanafusa, H.4
-
64
-
-
27744458852
-
FAK signaling is critical for ErbB-2/ErbB-3 receptor cooperation for oncogenic transformation and invasion
-
Benlimame N., He Q., Jie S., Xiao D., Xu Y.J., Loignon M., Schlaepfer D.D., and Alaoui-Jamali M.A. FAK signaling is critical for ErbB-2/ErbB-3 receptor cooperation for oncogenic transformation and invasion. The Journal of Cell Biology 171 (2005) 505-516
-
(2005)
The Journal of Cell Biology
, vol.171
, pp. 505-516
-
-
Benlimame, N.1
He, Q.2
Jie, S.3
Xiao, D.4
Xu, Y.J.5
Loignon, M.6
Schlaepfer, D.D.7
Alaoui-Jamali, M.A.8
-
65
-
-
3142779450
-
Phosphorylation of focal adhesion kinase at tyrosine 861 is crucial for Ras transformation of fibroblasts
-
Lim Y., Han I., Jeon J., Park H., Bahk Y.Y., and Oh E.S. Phosphorylation of focal adhesion kinase at tyrosine 861 is crucial for Ras transformation of fibroblasts. The Journal of Biological Chemistry 279 (2004) 29060-29065
-
(2004)
The Journal of Biological Chemistry
, vol.279
, pp. 29060-29065
-
-
Lim, Y.1
Han, I.2
Jeon, J.3
Park, H.4
Bahk, Y.Y.5
Oh, E.S.6
-
67
-
-
67651085772
-
Signal transduction by focal adhesion kinase in cancer
-
Zhao J., and Guan J.L. Signal transduction by focal adhesion kinase in cancer. Cancer Metastasis Reviews 28 (2009) 35-49
-
(2009)
Cancer Metastasis Reviews
, vol.28
, pp. 35-49
-
-
Zhao, J.1
Guan, J.L.2
-
68
-
-
0029039421
-
Overexpression of the focal adhesion kinase (p125FAK) in invasive human tumors
-
Owens L.V., Xu L., Craven R.J., Dent G.A., Weiner T.M., Kornberg L., Liu E.T., and Cance W.G. Overexpression of the focal adhesion kinase (p125FAK) in invasive human tumors. Cancer Research 55 (1995) 2752-2755
-
(1995)
Cancer Research
, vol.55
, pp. 2752-2755
-
-
Owens, L.V.1
Xu, L.2
Craven, R.J.3
Dent, G.A.4
Weiner, T.M.5
Kornberg, L.6
Liu, E.T.7
Cance, W.G.8
-
69
-
-
0037343388
-
Focal adhesion kinase as a marker of malignant phenotype in breast and cervical carcinomas
-
Oktay M.H., Oktay K., Hamele-Bena D., Buyuk A., and Koss L.G. Focal adhesion kinase as a marker of malignant phenotype in breast and cervical carcinomas. Human Pathology 34 (2003) 240-245
-
(2003)
Human Pathology
, vol.34
, pp. 240-245
-
-
Oktay, M.H.1
Oktay, K.2
Hamele-Bena, D.3
Buyuk, A.4
Koss, L.G.5
-
70
-
-
9644275426
-
Upregulation of focal adhesion kinase (FAK) expression in ductal carcinoma in situ (DCIS) is an early event in breast tumorigenesis
-
Lightfoot Jr. H.M., Lark A., Livasy C.A., Moore D.T., Cowan D., Dressler L., Craven R.J., and Cance W.G. Upregulation of focal adhesion kinase (FAK) expression in ductal carcinoma in situ (DCIS) is an early event in breast tumorigenesis. Breast Cancer Research and Treatment 88 (2004) 109-116
-
(2004)
Breast Cancer Research and Treatment
, vol.88
, pp. 109-116
-
-
Lightfoot Jr., H.M.1
Lark, A.2
Livasy, C.A.3
Moore, D.T.4
Cowan, D.5
Dressler, L.6
Craven, R.J.7
Cance, W.G.8
-
71
-
-
0034044795
-
Immunohistochemical analyses of focal adhesion kinase expression in benign and malignant human breast and colon tissues: correlation with preinvasive and invasive phenotypes
-
Cance W.G., Harris J.E., Iacocca M.V., Roche E., Yang X., Chang J., Simkins S., and Xu L. Immunohistochemical analyses of focal adhesion kinase expression in benign and malignant human breast and colon tissues: correlation with preinvasive and invasive phenotypes. Clinical Cancer Research 6 (2000) 2417-2423
-
(2000)
Clinical Cancer Research
, vol.6
, pp. 2417-2423
-
-
Cance, W.G.1
Harris, J.E.2
Iacocca, M.V.3
Roche, E.4
Yang, X.5
Chang, J.6
Simkins, S.7
Xu, L.8
-
72
-
-
27144545759
-
Specific induction of pp125 focal adhesion kinase in human breast cancer
-
Watermann D.O., Gabriel B., Jager M., Orlowska-Volk M., Hasenburg A., zur Hausen A., Gitsch G., and Stickeler E. Specific induction of pp125 focal adhesion kinase in human breast cancer. British Journal of Cancer 93 (2005) 694-698
-
(2005)
British Journal of Cancer
, vol.93
, pp. 694-698
-
-
Watermann, D.O.1
Gabriel, B.2
Jager, M.3
Orlowska-Volk, M.4
Hasenburg, A.5
zur Hausen, A.6
Gitsch, G.7
Stickeler, E.8
-
73
-
-
24944531575
-
High focal adhesion kinase expression in invasive breast carcinomas is associated with an aggressive phenotype
-
Lark A.L., Livasy C.A., Dressler L., Moore D.T., Millikan R.C., Geradts J., Iacocca M., Cowan D., Little D., Craven R.J., and Cance W. High focal adhesion kinase expression in invasive breast carcinomas is associated with an aggressive phenotype. Modern Pathology 18 (2005) 1289-1294
-
(2005)
Modern Pathology
, vol.18
, pp. 1289-1294
-
-
Lark, A.L.1
Livasy, C.A.2
Dressler, L.3
Moore, D.T.4
Millikan, R.C.5
Geradts, J.6
Iacocca, M.7
Cowan, D.8
Little, D.9
Craven, R.J.10
Cance, W.11
-
74
-
-
61749094852
-
Ras- and PI3K-dependent breast tumorigenesis in mice and humans requires focal adhesion kinase signaling
-
Pylayeva Y., Gillen K.M., Gerald W., Beggs H.E., Reichardt L.F., and Giancotti F.G. Ras- and PI3K-dependent breast tumorigenesis in mice and humans requires focal adhesion kinase signaling. The Journal of Clinical Investigation 119 (2009) 252-266
-
(2009)
The Journal of Clinical Investigation
, vol.119
, pp. 252-266
-
-
Pylayeva, Y.1
Gillen, K.M.2
Gerald, W.3
Beggs, H.E.4
Reichardt, L.F.5
Giancotti, F.G.6
-
75
-
-
0033533746
-
Increased dosage and amplification of the focal adhesion kinase gene in human cancer cells
-
Agochiya M., Brunton V.G., Owens D.W., Parkinson E.K., Paraskeva C., Keith W.N., and Frame M.C. Increased dosage and amplification of the focal adhesion kinase gene in human cancer cells. Oncogene 18 (1999) 5646-5653
-
(1999)
Oncogene
, vol.18
, pp. 5646-5653
-
-
Agochiya, M.1
Brunton, V.G.2
Owens, D.W.3
Parkinson, E.K.4
Paraskeva, C.5
Keith, W.N.6
Frame, M.C.7
-
76
-
-
29044442658
-
Focal adhesion proteins as markers of malignant transformation and prognostic indicators in breast carcinoma
-
Madan R., Smolkin M.B., Cocker R., Fayyad R., and Oktay M.H. Focal adhesion proteins as markers of malignant transformation and prognostic indicators in breast carcinoma. Human Pathology 37 (2006) 9-15
-
(2006)
Human Pathology
, vol.37
, pp. 9-15
-
-
Madan, R.1
Smolkin, M.B.2
Cocker, R.3
Fayyad, R.4
Oktay, M.H.5
-
77
-
-
0034798461
-
Reduced expression of focal adhesion kinase in liver metastases compared with matched primary human colorectal adenocarcinomas
-
Ayaki M., Komatsu K., Mukai M., Murata K., Kameyama M., Ishiguro S., Miyoshi J., Tatsuta M., and Nakamura H. Reduced expression of focal adhesion kinase in liver metastases compared with matched primary human colorectal adenocarcinomas. Clinical Cancer Research 7 (2001) 3106-3112
-
(2001)
Clinical Cancer Research
, vol.7
, pp. 3106-3112
-
-
Ayaki, M.1
Komatsu, K.2
Mukai, M.3
Murata, K.4
Kameyama, M.5
Ishiguro, S.6
Miyoshi, J.7
Tatsuta, M.8
Nakamura, H.9
-
78
-
-
33646403416
-
Weak expression of focal adhesion kinase (pp125FAK) in patients with cervical cancer is associated with poor disease outcome
-
Gabriel B., zur Hausen A., Stickeler E., Dietz C., Gitsch G., Fischer D.C., Bouda J., Tempfer C., and Hasenburg A. Weak expression of focal adhesion kinase (pp125FAK) in patients with cervical cancer is associated with poor disease outcome. Clinical Cancer Research 12 (2006) 2476-2483
-
(2006)
Clinical Cancer Research
, vol.12
, pp. 2476-2483
-
-
Gabriel, B.1
zur Hausen, A.2
Stickeler, E.3
Dietz, C.4
Gitsch, G.5
Fischer, D.C.6
Bouda, J.7
Tempfer, C.8
Hasenburg, A.9
-
79
-
-
33745194972
-
Overexpression of focal adhesion kinase in head and neck squamous cell carcinoma is independent of fak gene copy number
-
Canel M., Secades P., Rodrigo J.P., Cabanillas R., Herrero A., Suarez C., and Chiara M.D. Overexpression of focal adhesion kinase in head and neck squamous cell carcinoma is independent of fak gene copy number. Clinical Cancer Research 12 (2006) 3272-3279
-
(2006)
Clinical Cancer Research
, vol.12
, pp. 3272-3279
-
-
Canel, M.1
Secades, P.2
Rodrigo, J.P.3
Cabanillas, R.4
Herrero, A.5
Suarez, C.6
Chiara, M.D.7
-
80
-
-
2442583529
-
Cloning and characterization of the promoter region of human focal adhesion kinase gene: nuclear factor kappa B and p53 binding sites
-
Golubovskaya V., Kaur A., and Cance W. Cloning and characterization of the promoter region of human focal adhesion kinase gene: nuclear factor kappa B and p53 binding sites. Biochimica et Biophysica Acta 1678 (2004) 111-125
-
(2004)
Biochimica et Biophysica Acta
, vol.1678
, pp. 111-125
-
-
Golubovskaya, V.1
Kaur, A.2
Cance, W.3
-
82
-
-
42949160485
-
p53 regulates FAK expression in human tumor cells
-
Golubovskaya V.M., Finch R., Kweh F., Massoll N.A., Campbell-Thompson M., Wallace M.R., and Cance W.G. p53 regulates FAK expression in human tumor cells. Molecular Carcinogenesis 47 (2008) 373-382
-
(2008)
Molecular Carcinogenesis
, vol.47
, pp. 373-382
-
-
Golubovskaya, V.M.1
Finch, R.2
Kweh, F.3
Massoll, N.A.4
Campbell-Thompson, M.5
Wallace, M.R.6
Cance, W.G.7
-
83
-
-
0034717285
-
Anti-apoptotic role of focal adhesion kinase (FAK). Induction of inhibitor-of-apoptosis proteins and apoptosis suppression by the overexpression of FAK in a human leukemic cell line, HL-60
-
Sonoda Y., Matsumoto Y., Funakoshi M., Yamamoto D., Hanks S.K., and Kasahara T. Anti-apoptotic role of focal adhesion kinase (FAK). Induction of inhibitor-of-apoptosis proteins and apoptosis suppression by the overexpression of FAK in a human leukemic cell line, HL-60. The Journal of Biological Chemistry 275 (2000) 16309-16315
-
(2000)
The Journal of Biological Chemistry
, vol.275
, pp. 16309-16315
-
-
Sonoda, Y.1
Matsumoto, Y.2
Funakoshi, M.3
Yamamoto, D.4
Hanks, S.K.5
Kasahara, T.6
-
84
-
-
0036679235
-
Apoptosis of rat hepatic stellate cells induced by anti-focal adhesion kinase antibody
-
Liu X.J., Yang L., Wu H.B., Qiang O., Huang M.H., and Wang Y.P. Apoptosis of rat hepatic stellate cells induced by anti-focal adhesion kinase antibody. World Journal of Gastroenterology 8 (2002) 734-738
-
(2002)
World Journal of Gastroenterology
, vol.8
, pp. 734-738
-
-
Liu, X.J.1
Yang, L.2
Wu, H.B.3
Qiang, O.4
Huang, M.H.5
Wang, Y.P.6
-
85
-
-
0029848157
-
Attenuation of the expression of the focal adhesion kinase induces apoptosis in tumor cells
-
Xu L.H., Owens L.V., Sturge G.C., Yang X., Liu E.T., Craven R.J., and Cance W.G. Attenuation of the expression of the focal adhesion kinase induces apoptosis in tumor cells. Cell Growth and Differentiation 7 (1996) 413-418
-
(1996)
Cell Growth and Differentiation
, vol.7
, pp. 413-418
-
-
Xu, L.H.1
Owens, L.V.2
Sturge, G.C.3
Yang, X.4
Liu, E.T.5
Craven, R.J.6
Cance, W.G.7
-
86
-
-
0035423156
-
PTEN-independent induction of caspase-mediated cell death and reduced invasion by the focal adhesion targeting domain (FAT) in human astrocytic brain tumors which highly express focal adhesion kinase (FAK)
-
Jones G., Machado Jr. J., Tolnay M., and Merlo A. PTEN-independent induction of caspase-mediated cell death and reduced invasion by the focal adhesion targeting domain (FAT) in human astrocytic brain tumors which highly express focal adhesion kinase (FAK). Cancer Research 61 (2001) 5688-5691
-
(2001)
Cancer Research
, vol.61
, pp. 5688-5691
-
-
Jones, G.1
Machado Jr., J.2
Tolnay, M.3
Merlo, A.4
-
87
-
-
2942531163
-
Focal adhesion kinase suppresses apoptosis by binding to the death domain of receptor-interacting protein
-
Kurenova E., Xu L.H., Yang X., Baldwin Jr. A.S., Craven R.J., Hanks S.K., Liu Z.G., and Cance W.G. Focal adhesion kinase suppresses apoptosis by binding to the death domain of receptor-interacting protein. Molecular and Cellular Biology 24 (2004) 4361-4371
-
(2004)
Molecular and Cellular Biology
, vol.24
, pp. 4361-4371
-
-
Kurenova, E.1
Xu, L.H.2
Yang, X.3
Baldwin Jr., A.S.4
Craven, R.J.5
Hanks, S.K.6
Liu, Z.G.7
Cance, W.G.8
-
88
-
-
0037064030
-
Dual inhibition of focal adhesion kinase and epidermal growth factor receptor pathways cooperatively induces death receptor-mediated apoptosis in human breast cancer cells
-
Golubovskaya V., Beviglia L., Xu L.H., Earp III H.S., Craven R., and Cance W. Dual inhibition of focal adhesion kinase and epidermal growth factor receptor pathways cooperatively induces death receptor-mediated apoptosis in human breast cancer cells. The Journal of Biological Chemistry 277 (2002) 38978-38987
-
(2002)
The Journal of Biological Chemistry
, vol.277
, pp. 38978-38987
-
-
Golubovskaya, V.1
Beviglia, L.2
Xu, L.H.3
Earp III, H.S.4
Craven, R.5
Cance, W.6
-
89
-
-
33745468872
-
Direct interaction of focal adhesion kinase (FAK) with Met is required for FAK to promote hepatocyte growth factor-induced cell invasion
-
Chen S.Y., and Chen H.C. Direct interaction of focal adhesion kinase (FAK) with Met is required for FAK to promote hepatocyte growth factor-induced cell invasion. Molecular and Cellular Biology 26 (2006) 5155-5167
-
(2006)
Molecular and Cellular Biology
, vol.26
, pp. 5155-5167
-
-
Chen, S.Y.1
Chen, H.C.2
-
90
-
-
32944475609
-
Vascular endothelial growth factor receptor-3 and focal adhesion kinase bind and suppress apoptosis in breast cancer cells
-
Garces C.A., Kurenova E.V., Golubovskaya V.M., and Cance W.G. Vascular endothelial growth factor receptor-3 and focal adhesion kinase bind and suppress apoptosis in breast cancer cells. Cancer Research 66 (2006) 1446-1454
-
(2006)
Cancer Research
, vol.66
, pp. 1446-1454
-
-
Garces, C.A.1
Kurenova, E.V.2
Golubovskaya, V.M.3
Cance, W.G.4
-
91
-
-
0032443850
-
The COOH-terminal domain of the focal adhesion kinase induces loss of adhesion and cell death in human tumor cells
-
Xu L.H., Yang X., Craven R.J., and Cance W.G. The COOH-terminal domain of the focal adhesion kinase induces loss of adhesion and cell death in human tumor cells. Cell Growth and Differentiation 9 (1998) 999-1005
-
(1998)
Cell Growth and Differentiation
, vol.9
, pp. 999-1005
-
-
Xu, L.H.1
Yang, X.2
Craven, R.J.3
Cance, W.G.4
-
92
-
-
58349117913
-
Transforming growth factor beta induces clustering of HER2 and integrins by activating Src-focal adhesion kinase and receptor association to the cytoskeleton
-
Wang S.E., Xiang B., Zent R., Quaranta V., Pozzi A., and Arteaga C.L. Transforming growth factor beta induces clustering of HER2 and integrins by activating Src-focal adhesion kinase and receptor association to the cytoskeleton. Cancer Research 69 (2009) 475-482
-
(2009)
Cancer Research
, vol.69
, pp. 475-482
-
-
Wang, S.E.1
Xiang, B.2
Zent, R.3
Quaranta, V.4
Pozzi, A.5
Arteaga, C.L.6
-
93
-
-
0033617357
-
Requirement of phosphatidylinositol 3-kinase in focal adhesion kinase-promoted cell migration
-
Reiske H.R., Kao S.C., Cary L.A., Guan J.L., Lai J.F., and Chen H.C. Requirement of phosphatidylinositol 3-kinase in focal adhesion kinase-promoted cell migration. The Journal of Biological Chemistry 274 (1999) 12361-12366
-
(1999)
The Journal of Biological Chemistry
, vol.274
, pp. 12361-12366
-
-
Reiske, H.R.1
Kao, S.C.2
Cary, L.A.3
Guan, J.L.4
Lai, J.F.5
Chen, H.C.6
-
94
-
-
0142227019
-
Targeting the PI3K-Akt pathway in human cancer: rationale and promise
-
Luo J., Manning B.D., and Cantley L.C. Targeting the PI3K-Akt pathway in human cancer: rationale and promise. Cancer Cell 4 (2003) 257-262
-
(2003)
Cancer Cell
, vol.4
, pp. 257-262
-
-
Luo, J.1
Manning, B.D.2
Cantley, L.C.3
-
95
-
-
32044466838
-
Exploiting the PI3K/AKT pathway for cancer drug discovery
-
Hennessy B.T., Smith D.L., Ram P.T., Lu Y., and Mills G.B. Exploiting the PI3K/AKT pathway for cancer drug discovery. Nature Reviews Drug Discovery 4 (2005) 988-1004
-
(2005)
Nature Reviews Drug Discovery
, vol.4
, pp. 988-1004
-
-
Hennessy, B.T.1
Smith, D.L.2
Ram, P.T.3
Lu, Y.4
Mills, G.B.5
-
96
-
-
0033578641
-
Suppression of ultraviolet irradiation-induced apoptosis by overexpression of focal adhesion kinase in Madin-Darby canine kidney cells
-
Chan P.C., Lai J.F., Cheng C.H., Tang M.J., Chiu C.C., and Chen H.C. Suppression of ultraviolet irradiation-induced apoptosis by overexpression of focal adhesion kinase in Madin-Darby canine kidney cells. The Journal of Biological Chemistry 274 (1999) 26901-26906
-
(1999)
The Journal of Biological Chemistry
, vol.274
, pp. 26901-26906
-
-
Chan, P.C.1
Lai, J.F.2
Cheng, C.H.3
Tang, M.J.4
Chiu, C.C.5
Chen, H.C.6
-
97
-
-
21644466387
-
Direct interaction of the N-terminal domain of focal adhesion kinase with the N-terminal transactivation domain of p53
-
Golubovskaya V.M., Finch R., and Cance W.G. Direct interaction of the N-terminal domain of focal adhesion kinase with the N-terminal transactivation domain of p53. The Journal of Biological Chemistry 280 (2005) 25008-25021
-
(2005)
The Journal of Biological Chemistry
, vol.280
, pp. 25008-25021
-
-
Golubovskaya, V.M.1
Finch, R.2
Cance, W.G.3
-
98
-
-
38149070791
-
Nuclear FAK promotes cell proliferation and survival through FERM-enhanced p53 degradation
-
Lim S.T., Chen X.L., Lim Y., Hanson D.A., Vo T.T., Howerton K., Larocque N., Fisher S.J., Schlaepfer D.D., and Ilic D. Nuclear FAK promotes cell proliferation and survival through FERM-enhanced p53 degradation. Molecular Cell 29 (2008) 9-22
-
(2008)
Molecular Cell
, vol.29
, pp. 9-22
-
-
Lim, S.T.1
Chen, X.L.2
Lim, Y.3
Hanson, D.A.4
Vo, T.T.5
Howerton, K.6
Larocque, N.7
Fisher, S.J.8
Schlaepfer, D.D.9
Ilic, D.10
-
99
-
-
0038433306
-
Identification of transcription factor KLF8 as a downstream target of focal adhesion kinase in its regulation of cyclin D1 and cell cycle progression
-
Zhao J., Bian Z.C., Yee K., Chen B.P., Chien S., and Guan J.L. Identification of transcription factor KLF8 as a downstream target of focal adhesion kinase in its regulation of cyclin D1 and cell cycle progression. Molecular Cell 11 (2003) 1503-1515
-
(2003)
Molecular Cell
, vol.11
, pp. 1503-1515
-
-
Zhao, J.1
Bian, Z.C.2
Yee, K.3
Chen, B.P.4
Chien, S.5
Guan, J.L.6
-
100
-
-
0037061762
-
Inhibition of FAK signaling activated by urokinase receptor induces dormancy in human carcinoma cells in vivo
-
Aguirre Ghiso J.A. Inhibition of FAK signaling activated by urokinase receptor induces dormancy in human carcinoma cells in vivo. Oncogene 21 (2002) 2513-2524
-
(2002)
Oncogene
, vol.21
, pp. 2513-2524
-
-
Aguirre Ghiso, J.A.1
-
101
-
-
55349105491
-
Mammary epithelial-specific disruption of focal adhesion kinase retards tumor formation and metastasis in a transgenic mouse model of human breast cancer
-
Provenzano P.P., Inman D.R., Eliceiri K.W., Beggs H.E., and Keely P.J. Mammary epithelial-specific disruption of focal adhesion kinase retards tumor formation and metastasis in a transgenic mouse model of human breast cancer. The American Journal of Pathology 173 (2008) 1551-1565
-
(2008)
The American Journal of Pathology
, vol.173
, pp. 1551-1565
-
-
Provenzano, P.P.1
Inman, D.R.2
Eliceiri, K.W.3
Beggs, H.E.4
Keely, P.J.5
-
102
-
-
58349108303
-
Mammary epithelial-specific ablation of the focal adhesion kinase suppresses mammary tumorigenesis by affecting mammary cancer stem/progenitor cells
-
Luo M., Fan H., Nagy T., Wei H., Wang C., Liu S., Wicha M.S., and Guan J.L. Mammary epithelial-specific ablation of the focal adhesion kinase suppresses mammary tumorigenesis by affecting mammary cancer stem/progenitor cells. Cancer Research 69 (2009) 466-474
-
(2009)
Cancer Research
, vol.69
, pp. 466-474
-
-
Luo, M.1
Fan, H.2
Nagy, T.3
Wei, H.4
Wang, C.5
Liu, S.6
Wicha, M.S.7
Guan, J.L.8
-
103
-
-
1642586962
-
FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly
-
Webb D.J., Donais K., Whitmore L.A., Thomas S.M., Turner C.E., Parsons J.T., and Horwitz A.F. FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly. Nature Cell Biology 6 (2004) 154-161
-
(2004)
Nature Cell Biology
, vol.6
, pp. 154-161
-
-
Webb, D.J.1
Donais, K.2
Whitmore, L.A.3
Thomas, S.M.4
Turner, C.E.5
Parsons, J.T.6
Horwitz, A.F.7
-
104
-
-
33847413148
-
Focal adhesion kinase modulates tension signaling to control actin and focal adhesion dynamics
-
Schober M., Raghavan S., Nikolova M., Polak L., Pasolli H.A., Beggs H.E., Reichardt L.F., and Fuchs E. Focal adhesion kinase modulates tension signaling to control actin and focal adhesion dynamics. The Journal of Cell Biology 176 (2007) 667-680
-
(2007)
The Journal of Cell Biology
, vol.176
, pp. 667-680
-
-
Schober, M.1
Raghavan, S.2
Nikolova, M.3
Polak, L.4
Pasolli, H.A.5
Beggs, H.E.6
Reichardt, L.F.7
Fuchs, E.8
-
105
-
-
34249776956
-
Src kinase promotes adhesion-independent activation of FAK and enhances cellular migration in tamoxifen-resistant breast cancer cells
-
Hiscox S., Jordan N.J., Morgan L., Green T.P., and Nicholson R.I. Src kinase promotes adhesion-independent activation of FAK and enhances cellular migration in tamoxifen-resistant breast cancer cells. Clinical and Experimental Metastasis 24 (2007) 157-167
-
(2007)
Clinical and Experimental Metastasis
, vol.24
, pp. 157-167
-
-
Hiscox, S.1
Jordan, N.J.2
Morgan, L.3
Green, T.P.4
Nicholson, R.I.5
-
106
-
-
33748286819
-
Integrin-regulated FAK-Src signaling in normal and cancer cells
-
Mitra S.K., and Schlaepfer D.D. Integrin-regulated FAK-Src signaling in normal and cancer cells. Current Opinion in Cell Biology 18 (2006) 516-523
-
(2006)
Current Opinion in Cell Biology
, vol.18
, pp. 516-523
-
-
Mitra, S.K.1
Schlaepfer, D.D.2
-
107
-
-
0032509565
-
Identification of p130Cas as a mediator of focal adhesion kinase-promoted cell migration
-
Cary L.A., Han D.C., Polte T.R., Hanks S.K., and Guan J.L. Identification of p130Cas as a mediator of focal adhesion kinase-promoted cell migration. The Journal of Cell Biology 140 (1998) 211-221
-
(1998)
The Journal of Cell Biology
, vol.140
, pp. 211-221
-
-
Cary, L.A.1
Han, D.C.2
Polte, T.R.3
Hanks, S.K.4
Guan, J.L.5
-
108
-
-
0032559562
-
CAS/Crk coupling serves as a "molecular switch" for induction of cell migration
-
Klemke R.L., Leng J., Molander R., Brooks P.C., Vuori K., and Cheresh D.A. CAS/Crk coupling serves as a "molecular switch" for induction of cell migration. The Journal of Cell Biology 140 (1998) 961-972
-
(1998)
The Journal of Cell Biology
, vol.140
, pp. 961-972
-
-
Klemke, R.L.1
Leng, J.2
Molander, R.3
Brooks, P.C.4
Vuori, K.5
Cheresh, D.A.6
-
109
-
-
0041924982
-
A novel role for FAK as a protease-targeting adaptor protein: regulation by p42 ERK and Src
-
Carragher N.O., Westhoff M.A., Fincham V.J., Schaller M.D., and Frame M.C. A novel role for FAK as a protease-targeting adaptor protein: regulation by p42 ERK and Src. Current Biology 13 (2003) 1442-1450
-
(2003)
Current Biology
, vol.13
, pp. 1442-1450
-
-
Carragher, N.O.1
Westhoff, M.A.2
Fincham, V.J.3
Schaller, M.D.4
Frame, M.C.5
-
110
-
-
60849093481
-
A novel role of ERK5 in integrin-mediated cell adhesion and motility in cancer cells via Fak signaling
-
Sawhney R.S., Liu W., and Brattain M.G. A novel role of ERK5 in integrin-mediated cell adhesion and motility in cancer cells via Fak signaling. Journal of Cellular Physiology 219 (2009) 152-161
-
(2009)
Journal of Cellular Physiology
, vol.219
, pp. 152-161
-
-
Sawhney, R.S.1
Liu, W.2
Brattain, M.G.3
-
111
-
-
76849101138
-
Tyrosine phosphorylation of Grb7 by FAK in the regulation of cell migration, proliferation, and tumorigenesis
-
Chu P.Y., Huang L.Y., Hsu C.H., Liang C.C., Guan J.L., Hung T.H., and Shen T.L. Tyrosine phosphorylation of Grb7 by FAK in the regulation of cell migration, proliferation, and tumorigenesis. The Journal of Biological Chemistry (2009)
-
(2009)
The Journal of Biological Chemistry
-
-
Chu, P.Y.1
Huang, L.Y.2
Hsu, C.H.3
Liang, C.C.4
Guan, J.L.5
Hung, T.H.6
Shen, T.L.7
-
112
-
-
0037072731
-
Roles of Rho-associated kinase and myosin light chain kinase in morphological and migratory defects of focal adhesion kinase-null cells
-
Chen B.H., Tzen J.T., Bresnick A.R., and Chen H.C. Roles of Rho-associated kinase and myosin light chain kinase in morphological and migratory defects of focal adhesion kinase-null cells. The Journal of Biological Chemistry 277 (2002) 33857-33863
-
(2002)
The Journal of Biological Chemistry
, vol.277
, pp. 33857-33863
-
-
Chen, B.H.1
Tzen, J.T.2
Bresnick, A.R.3
Chen, H.C.4
-
113
-
-
0033731010
-
Focal adhesion kinase suppresses Rho activity to promote focal adhesion turnover
-
Ren X.D., Kiosses W.B., Sieg D.J., Otey C.A., Schlaepfer D.D., and Schwartz M.A. Focal adhesion kinase suppresses Rho activity to promote focal adhesion turnover. Journal of Cell Science 113 Pt 20 (2000) 3673-3678
-
(2000)
Journal of Cell Science
, vol.113
, Issue.PART 20
, pp. 3673-3678
-
-
Ren, X.D.1
Kiosses, W.B.2
Sieg, D.J.3
Otey, C.A.4
Schlaepfer, D.D.5
Schwartz, M.A.6
-
114
-
-
1542304700
-
Focal adhesion kinase regulation of N-WASP subcellular localization and function
-
Wu X., Suetsugu S., Cooper L.A., Takenawa T., and Guan J.L. Focal adhesion kinase regulation of N-WASP subcellular localization and function. The Journal of Biological Chemistry 279 (2004) 9565-9576
-
(2004)
The Journal of Biological Chemistry
, vol.279
, pp. 9565-9576
-
-
Wu, X.1
Suetsugu, S.2
Cooper, L.A.3
Takenawa, T.4
Guan, J.L.5
-
115
-
-
34548316989
-
Focal adhesion kinase controls actin assembly via a FERM-mediated interaction with the Arp2/3 complex
-
Serrels B., Serrels A., Brunton V.G., Holt M., McLean G.W., Gray C.H., Jones G.E., and Frame M.C. Focal adhesion kinase controls actin assembly via a FERM-mediated interaction with the Arp2/3 complex. Nature Cell Biology 9 (2007) 1046-1056
-
(2007)
Nature Cell Biology
, vol.9
, pp. 1046-1056
-
-
Serrels, B.1
Serrels, A.2
Brunton, V.G.3
Holt, M.4
McLean, G.W.5
Gray, C.H.6
Jones, G.E.7
Frame, M.C.8
-
116
-
-
21744435478
-
The role of focal-adhesion kinase in cancer - a new therapeutic opportunity
-
McLean G.W., Carragher N.O., Avizienyte E., Evans J., Brunton V.G., and Frame M.C. The role of focal-adhesion kinase in cancer - a new therapeutic opportunity. Nature Reviews Cancer 5 (2005) 505-515
-
(2005)
Nature Reviews Cancer
, vol.5
, pp. 505-515
-
-
McLean, G.W.1
Carragher, N.O.2
Avizienyte, E.3
Evans, J.4
Brunton, V.G.5
Frame, M.C.6
-
117
-
-
29044447052
-
Mechanisms of focal adhesion kinase regulation
-
Cohen L.A., and Guan J.L. Mechanisms of focal adhesion kinase regulation. Current Cancer Drug Targets 5 (2005) 629-643
-
(2005)
Current Cancer Drug Targets
, vol.5
, pp. 629-643
-
-
Cohen, L.A.1
Guan, J.L.2
-
118
-
-
33749485761
-
Disruption of focal adhesion kinase slows transendothelial migration of AU-565 breast cancer cells
-
Earley S., and Plopper G.E. Disruption of focal adhesion kinase slows transendothelial migration of AU-565 breast cancer cells. Biochemical and Biophysical Research Communications 350 (2006) 405-412
-
(2006)
Biochemical and Biophysical Research Communications
, vol.350
, pp. 405-412
-
-
Earley, S.1
Plopper, G.E.2
-
119
-
-
37449007763
-
Phosphorylation of focal adhesion kinase promotes extravasation of breast cancer cells
-
Earley S., and Plopper G.E. Phosphorylation of focal adhesion kinase promotes extravasation of breast cancer cells. Biochemical and Biophysical Research Communications 366 (2008) 476-482
-
(2008)
Biochemical and Biophysical Research Communications
, vol.366
, pp. 476-482
-
-
Earley, S.1
Plopper, G.E.2
-
120
-
-
34249059285
-
Phosphorylation of FAK, PI-3K, and impaired actin organization in CK-positive micrometastatic breast cancer cells
-
Kallergi G., Mavroudis D., Georgoulias V., Stournaras C., and FAK P.o. Phosphorylation of FAK, PI-3K, and impaired actin organization in CK-positive micrometastatic breast cancer cells. Molecular Medicine 13 (2007) 79-88
-
(2007)
Molecular Medicine
, vol.13
, pp. 79-88
-
-
Kallergi, G.1
Mavroudis, D.2
Georgoulias, V.3
Stournaras, C.4
FAK, P.o.5
-
121
-
-
0032790741
-
Hydrogen peroxide stimulates tyrosine phosphorylation of focal adhesion kinase in vascular endothelial cells
-
Vepa S., Scribner W.M., Parinandi N.L., English D., Garcia J.G., and Natarajan V. Hydrogen peroxide stimulates tyrosine phosphorylation of focal adhesion kinase in vascular endothelial cells. The American Journal of Physiology 277 (1999) L150-158
-
(1999)
The American Journal of Physiology
, vol.277
-
-
Vepa, S.1
Scribner, W.M.2
Parinandi, N.L.3
English, D.4
Garcia, J.G.5
Natarajan, V.6
-
122
-
-
0032403050
-
Reactive oxygen species activate focal adhesion kinase, paxillin and p130cas tyrosine phosphorylation in endothelial cells
-
Gozin A., Franzini E., Andrieu V., Da Costa L., Rollet-Labelle E., and Pasquier C. Reactive oxygen species activate focal adhesion kinase, paxillin and p130cas tyrosine phosphorylation in endothelial cells. Free Radical Biology and Medicine 25 (1998) 1021-1032
-
(1998)
Free Radical Biology and Medicine
, vol.25
, pp. 1021-1032
-
-
Gozin, A.1
Franzini, E.2
Andrieu, V.3
Da Costa, L.4
Rollet-Labelle, E.5
Pasquier, C.6
-
124
-
-
0242391845
-
Focal adhesion kinase mediates porcine venular hyperpermeability elicited by vascular endothelial growth factor
-
Wu M.H., Guo M., Yuan S.Y., and Granger H.J. Focal adhesion kinase mediates porcine venular hyperpermeability elicited by vascular endothelial growth factor. The Journal of Physiology 552 (2003) 691-699
-
(2003)
The Journal of Physiology
, vol.552
, pp. 691-699
-
-
Wu, M.H.1
Guo, M.2
Yuan, S.Y.3
Granger, H.J.4
-
125
-
-
33750850081
-
Tyrosine phosphorylation of paxillin/pp125FAK and microvascular endothelial barrier function
-
Yuan Y., Meng F.Y., Huang Q., Hawker J., and Wu H.M. Tyrosine phosphorylation of paxillin/pp125FAK and microvascular endothelial barrier function. The American Journal of Physiology 275 (1998) H84-93
-
(1998)
The American Journal of Physiology
, vol.275
-
-
Yuan, Y.1
Meng, F.Y.2
Huang, Q.3
Hawker, J.4
Wu, H.M.5
-
126
-
-
60349114065
-
Regulation of focal adhesion turnover by ErbB signalling in invasive breast cancer cells
-
Xu Y., Benlimame N., Su J., He Q., and Alaoui-Jamali M.A. Regulation of focal adhesion turnover by ErbB signalling in invasive breast cancer cells. British Journal of Cancer 100 (2009) 633-643
-
(2009)
British Journal of Cancer
, vol.100
, pp. 633-643
-
-
Xu, Y.1
Benlimame, N.2
Su, J.3
He, Q.4
Alaoui-Jamali, M.A.5
-
127
-
-
3543114271
-
Foot and mouth: podosomes, invadopodia and circular dorsal ruffles
-
Buccione R., Orth J.D., and McNiven M.A. Foot and mouth: podosomes, invadopodia and circular dorsal ruffles. Nature Reviews 5 (2004) 647-657
-
(2004)
Nature Reviews
, vol.5
, pp. 647-657
-
-
Buccione, R.1
Orth, J.D.2
McNiven, M.A.3
-
128
-
-
33748979745
-
Invadopodia: specialized cell structures for cancer invasion
-
Weaver A.M. Invadopodia: specialized cell structures for cancer invasion. Clinical and Experimental Metastasis 23 (2006) 97-105
-
(2006)
Clinical and Experimental Metastasis
, vol.23
, pp. 97-105
-
-
Weaver, A.M.1
-
129
-
-
65349127021
-
FAK alters invadopodia and focal adhesion composition and dynamics to regulate breast cancer invasion
-
Chan K.T., Cortesio C.L., and Huttenlocher A. FAK alters invadopodia and focal adhesion composition and dynamics to regulate breast cancer invasion. The Journal of Cell Biology 185 (2009) 357-370
-
(2009)
The Journal of Cell Biology
, vol.185
, pp. 357-370
-
-
Chan, K.T.1
Cortesio, C.L.2
Huttenlocher, A.3
-
130
-
-
0032031062
-
Both focal adhesion kinase and c-Ras are required for the enhanced matrix metalloproteinase 9 secretion by fibronectin in ovarian cancer cells
-
Shibata K., Kikkawa F., Nawa A., Thant A.A., Naruse K., Mizutani S., and Hamaguchi M. Both focal adhesion kinase and c-Ras are required for the enhanced matrix metalloproteinase 9 secretion by fibronectin in ovarian cancer cells. Cancer Research 58 (1998) 900-903
-
(1998)
Cancer Research
, vol.58
, pp. 900-903
-
-
Shibata, K.1
Kikkawa, F.2
Nawa, A.3
Thant, A.A.4
Naruse, K.5
Mizutani, S.6
Hamaguchi, M.7
-
131
-
-
0036570080
-
Increased Src activity disrupts cadherin/catenin-mediated homotypic adhesion in human colon cancer and transformed rodent cells
-
Irby R.B., and Yeatman T.J. Increased Src activity disrupts cadherin/catenin-mediated homotypic adhesion in human colon cancer and transformed rodent cells. Cancer Research 62 (2002) 2669-2674
-
(2002)
Cancer Research
, vol.62
, pp. 2669-2674
-
-
Irby, R.B.1
Yeatman, T.J.2
-
132
-
-
24644471128
-
Src and FAK signalling controls adhesion fate and the epithelial-to-mesenchymal transition
-
Avizienyte E., and Frame M.C. Src and FAK signalling controls adhesion fate and the epithelial-to-mesenchymal transition. Current Opinion in Cell Biology 17 (2005) 542-547
-
(2005)
Current Opinion in Cell Biology
, vol.17
, pp. 542-547
-
-
Avizienyte, E.1
Frame, M.C.2
-
133
-
-
0036048217
-
Src-induced de-regulation of E-cadherin in colon cancer cells requires integrin signalling
-
Avizienyte E., Wyke A.W., Jones R.J., McLean G.W., Westhoff M.A., Brunton V.G., and Frame M.C. Src-induced de-regulation of E-cadherin in colon cancer cells requires integrin signalling. Nature Cell Biology 4 (2002) 632-638
-
(2002)
Nature Cell Biology
, vol.4
, pp. 632-638
-
-
Avizienyte, E.1
Wyke, A.W.2
Jones, R.J.3
McLean, G.W.4
Westhoff, M.A.5
Brunton, V.G.6
Frame, M.C.7
-
134
-
-
4644300725
-
Epithelial mesenchymal transition is a characteristic of hyperplasias and tumors in mammary gland from MMTV-Cripto-1 transgenic mice
-
Strizzi L., Bianco C., Normanno N., Seno M., Wechselberger C., Wallace-Jones B., Khan N.I., Hirota M., Sun Y., Sanicola M., and Salomon D.S. Epithelial mesenchymal transition is a characteristic of hyperplasias and tumors in mammary gland from MMTV-Cripto-1 transgenic mice. Journal of Cellular Physiology 201 (2004) 266-276
-
(2004)
Journal of Cellular Physiology
, vol.201
, pp. 266-276
-
-
Strizzi, L.1
Bianco, C.2
Normanno, N.3
Seno, M.4
Wechselberger, C.5
Wallace-Jones, B.6
Khan, N.I.7
Hirota, M.8
Sun, Y.9
Sanicola, M.10
Salomon, D.S.11
-
135
-
-
0035837360
-
Different modes and qualities of tyrosine phosphorylation of Fak and Pyk2 during epithelial-mesenchymal transdifferentiation and cell migration: analysis of specific phosphorylation events using site-directed antibodies
-
Nakamura K., Yano H., Schaefer E., and Sabe H. Different modes and qualities of tyrosine phosphorylation of Fak and Pyk2 during epithelial-mesenchymal transdifferentiation and cell migration: analysis of specific phosphorylation events using site-directed antibodies. Oncogene 20 (2001) 2626-2635
-
(2001)
Oncogene
, vol.20
, pp. 2626-2635
-
-
Nakamura, K.1
Yano, H.2
Schaefer, E.3
Sabe, H.4
-
136
-
-
46649102319
-
Caveolin-1 up-regulation during epithelial to mesenchymal transition is mediated by focal adhesion kinase
-
Bailey K.M., and Liu J. Caveolin-1 up-regulation during epithelial to mesenchymal transition is mediated by focal adhesion kinase. The Journal of Biological Chemistry 283 (2008) 13714-13724
-
(2008)
The Journal of Biological Chemistry
, vol.283
, pp. 13714-13724
-
-
Bailey, K.M.1
Liu, J.2
-
137
-
-
36549031307
-
TGFbeta-induced EMT requires focal adhesion kinase (FAK) signaling
-
Cicchini C., Laudadio I., Citarella F., Corazzari M., Steindler C., Conigliaro A., Fantoni A., Amicone L., and Tripodi M. TGFbeta-induced EMT requires focal adhesion kinase (FAK) signaling. Experimental Cell Research 314 (2008) 143-152
-
(2008)
Experimental Cell Research
, vol.314
, pp. 143-152
-
-
Cicchini, C.1
Laudadio, I.2
Citarella, F.3
Corazzari, M.4
Steindler, C.5
Conigliaro, A.6
Fantoni, A.7
Amicone, L.8
Tripodi, M.9
-
138
-
-
20444445870
-
Disabled-2 (Dab2) is required for transforming growth factor beta-induced epithelial to mesenchymal transition (EMT)
-
Prunier C., and Howe P.H. Disabled-2 (Dab2) is required for transforming growth factor beta-induced epithelial to mesenchymal transition (EMT). The Journal of Biological Chemistry 280 (2005) 17540-17548
-
(2005)
The Journal of Biological Chemistry
, vol.280
, pp. 17540-17548
-
-
Prunier, C.1
Howe, P.H.2
-
139
-
-
33847152222
-
Focal adhesion kinase and E-cadherin as markers for nodal metastasis in laryngeal cancer
-
Rodrigo J.P., Dominguez F., Suarez V., Canel M., Secades P., and Chiara M.D. Focal adhesion kinase and E-cadherin as markers for nodal metastasis in laryngeal cancer. Archives of Otolaryngology - Head and Neck Surgery 133 (2007) 145-150
-
(2007)
Archives of Otolaryngology - Head and Neck Surgery
, vol.133
, pp. 145-150
-
-
Rodrigo, J.P.1
Dominguez, F.2
Suarez, V.3
Canel, M.4
Secades, P.5
Chiara, M.D.6
-
140
-
-
0037501115
-
Focal adhesion kinase is expressed in the angiogenic blood vessels of malignant astrocytic tumors in vivo and promotes capillary tube formation of brain microvascular endothelial cells
-
Haskell H., Natarajan M., Hecker T.P., Ding Q., Stewart Jr. J., Grammer J.R., and Gladson C.L. Focal adhesion kinase is expressed in the angiogenic blood vessels of malignant astrocytic tumors in vivo and promotes capillary tube formation of brain microvascular endothelial cells. Clinical Cancer Research 9 (2003) 2157-2165
-
(2003)
Clinical Cancer Research
, vol.9
, pp. 2157-2165
-
-
Haskell, H.1
Natarajan, M.2
Hecker, T.P.3
Ding, Q.4
Stewart Jr., J.5
Grammer, J.R.6
Gladson, C.L.7
-
141
-
-
0033121275
-
The role of alphav integrins during angiogenesis: insights into potential mechanisms of action and clinical development
-
Eliceiri B.P., and Cheresh D.A. The role of alphav integrins during angiogenesis: insights into potential mechanisms of action and clinical development. The Journal of Clinical Investigation 103 (1999) 1227-1230
-
(1999)
The Journal of Clinical Investigation
, vol.103
, pp. 1227-1230
-
-
Eliceiri, B.P.1
Cheresh, D.A.2
-
142
-
-
0028670833
-
Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels
-
Brooks P.C., Montgomery A.M., Rosenfeld M., Reisfeld R.A., Hu T., Klier G., and Cheresh D.A. Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell 79 (1994) 1157-1164
-
(1994)
Cell
, vol.79
, pp. 1157-1164
-
-
Brooks, P.C.1
Montgomery, A.M.2
Rosenfeld, M.3
Reisfeld, R.A.4
Hu, T.5
Klier, G.6
Cheresh, D.A.7
-
143
-
-
0028972105
-
Antiintegrin alpha v beta 3 blocks human breast cancer growth and angiogenesis in human skin
-
Brooks P.C., Stromblad S., Klemke R., Visscher D., Sarkar F.H., and Cheresh D.A. Antiintegrin alpha v beta 3 blocks human breast cancer growth and angiogenesis in human skin. The Journal of Clinical Investigation 96 (1995) 1815-1822
-
(1995)
The Journal of Clinical Investigation
, vol.96
, pp. 1815-1822
-
-
Brooks, P.C.1
Stromblad, S.2
Klemke, R.3
Visscher, D.4
Sarkar, F.H.5
Cheresh, D.A.6
-
144
-
-
33749188459
-
Intrinsic FAK activity and Y925 phosphorylation facilitate an angiogenic switch in tumors
-
Mitra S.K., Mikolon D., Molina J.E., Hsia D.A., Hanson D.A., Chi A., Lim S.T., Bernard-Trifilo J.A., Ilic D., Stupack D.G., Cheresh D.A., and Schlaepfer D.D. Intrinsic FAK activity and Y925 phosphorylation facilitate an angiogenic switch in tumors. Oncogene 25 (2006) 5969-5984
-
(2006)
Oncogene
, vol.25
, pp. 5969-5984
-
-
Mitra, S.K.1
Mikolon, D.2
Molina, J.E.3
Hsia, D.A.4
Hanson, D.A.5
Chi, A.6
Lim, S.T.7
Bernard-Trifilo, J.A.8
Ilic, D.9
Stupack, D.G.10
Cheresh, D.A.11
Schlaepfer, D.D.12
-
145
-
-
66149099270
-
Role of focal adhesion kinase Ser-732 phosphorylation in centrosome function during mitosis
-
Park A.Y., Shen T.L., Chien S., and Guan J.L. Role of focal adhesion kinase Ser-732 phosphorylation in centrosome function during mitosis. The Journal of Biological Chemistry 284 (2009) 9418-9425
-
(2009)
The Journal of Biological Chemistry
, vol.284
, pp. 9418-9425
-
-
Park, A.Y.1
Shen, T.L.2
Chien, S.3
Guan, J.L.4
-
146
-
-
19644388523
-
Requirement for focal adhesion kinase in the early phase of mammary adenocarcinoma lung metastasis formation
-
van Nimwegen M.J., Verkoeijen S., van Buren L., Burg D., and van de Water B. Requirement for focal adhesion kinase in the early phase of mammary adenocarcinoma lung metastasis formation. Cancer Research 65 (2005) 4698-4706
-
(2005)
Cancer Research
, vol.65
, pp. 4698-4706
-
-
van Nimwegen, M.J.1
Verkoeijen, S.2
van Buren, L.3
Burg, D.4
van de Water, B.5
-
147
-
-
33746481375
-
Intrinsic focal adhesion kinase activity controls orthotopic breast carcinoma metastasis via the regulation of urokinase plasminogen activator expression in a syngeneic tumor model
-
Mitra S.K., Lim S.T., Chi A., and Schlaepfer D.D. Intrinsic focal adhesion kinase activity controls orthotopic breast carcinoma metastasis via the regulation of urokinase plasminogen activator expression in a syngeneic tumor model. Oncogene 25 (2006) 4429-4440
-
(2006)
Oncogene
, vol.25
, pp. 4429-4440
-
-
Mitra, S.K.1
Lim, S.T.2
Chi, A.3
Schlaepfer, D.D.4
-
148
-
-
55349138779
-
Focal adhesion kinase-related proline-rich tyrosine kinase 2 and focal adhesion kinase are co-overexpressed in early-stage and invasive ErbB-2-positive breast cancer and cooperate for breast cancer cell tumorigenesis and invasiveness
-
Behmoaram E., Bijian K., Jie S., Xu Y., Darnel A., Bismar T.A., and Alaoui-Jamali M.A. Focal adhesion kinase-related proline-rich tyrosine kinase 2 and focal adhesion kinase are co-overexpressed in early-stage and invasive ErbB-2-positive breast cancer and cooperate for breast cancer cell tumorigenesis and invasiveness. The American Journal of Pathology 173 (2008) 1540-1550
-
(2008)
The American Journal of Pathology
, vol.173
, pp. 1540-1550
-
-
Behmoaram, E.1
Bijian, K.2
Jie, S.3
Xu, Y.4
Darnel, A.5
Bismar, T.A.6
Alaoui-Jamali, M.A.7
-
149
-
-
34548268026
-
Modelling breast cancer: one size does not fit all
-
Vargo-Gogola T., and Rosen J.M. Modelling breast cancer: one size does not fit all. Nature Reviews Cancer 7 (2007) 659-672
-
(2007)
Nature Reviews Cancer
, vol.7
, pp. 659-672
-
-
Vargo-Gogola, T.1
Rosen, J.M.2
-
150
-
-
0142244181
-
Progression to malignancy in the polyoma middle T oncoprotein mouse breast cancer model provides a reliable model for human diseases
-
Lin E.Y., Jones J.G., Li P., Zhu L., Whitney K.D., Muller W.J., and Pollard J.W. Progression to malignancy in the polyoma middle T oncoprotein mouse breast cancer model provides a reliable model for human diseases. The American Journal of Pathology 163 (2003) 2113-2126
-
(2003)
The American Journal of Pathology
, vol.163
, pp. 2113-2126
-
-
Lin, E.Y.1
Jones, J.G.2
Li, P.3
Zhu, L.4
Whitney, K.D.5
Muller, W.J.6
Pollard, J.W.7
-
151
-
-
38049098089
-
Mammary epithelial-specific disruption of the focal adhesion kinase blocks mammary tumor progression
-
Lahlou H., Sanguin-Gendreau V., Zuo D., Cardiff R.D., McLean G.W., Frame M.C., and Muller W.J. Mammary epithelial-specific disruption of the focal adhesion kinase blocks mammary tumor progression. Proceedings of the National Academy of Sciences of the United States of America 104 (2007) 20302-20307
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, pp. 20302-20307
-
-
Lahlou, H.1
Sanguin-Gendreau, V.2
Zuo, D.3
Cardiff, R.D.4
McLean, G.W.5
Frame, M.C.6
Muller, W.J.7
-
152
-
-
0035890383
-
Transgenic polyoma middle-T mice model premalignant mammary disease
-
Maglione J.E., Moghanaki D., Young L.J., Manner C.K., Ellies L.G., Joseph S.O., Nicholson B., Cardiff R.D., and MacLeod C.L. Transgenic polyoma middle-T mice model premalignant mammary disease. Cancer Research 61 (2001) 8298-8305
-
(2001)
Cancer Research
, vol.61
, pp. 8298-8305
-
-
Maglione, J.E.1
Moghanaki, D.2
Young, L.J.3
Manner, C.K.4
Ellies, L.G.5
Joseph, S.O.6
Nicholson, B.7
Cardiff, R.D.8
MacLeod, C.L.9
-
153
-
-
0037388204
-
Prospective identification of tumorigenic breast cancer cells
-
Al-Hajj M., Wicha M.S., Benito-Hernandez A., Morrison S.J., and Clarke M.F. Prospective identification of tumorigenic breast cancer cells. Proceedings of the National Academy of Sciences of the United States of America 100 (2003) 3983-3988
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, pp. 3983-3988
-
-
Al-Hajj, M.1
Wicha, M.S.2
Benito-Hernandez, A.3
Morrison, S.J.4
Clarke, M.F.5
-
154
-
-
33846512398
-
Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma
-
Prince M.E., Sivanandan R., Kaczorowski A., Wolf G.T., Kaplan M.J., Dalerba P., Weissman I.L., Clarke M.F., and Ailles L.E. Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma. Proceedings of the National Academy of Sciences of the United States of America 104 (2007) 973-978
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, pp. 973-978
-
-
Prince, M.E.1
Sivanandan, R.2
Kaczorowski, A.3
Wolf, G.T.4
Kaplan, M.J.5
Dalerba, P.6
Weissman, I.L.7
Clarke, M.F.8
Ailles, L.E.9
-
155
-
-
33846100356
-
A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
-
O'Brien C.A., Pollett A., Gallinger S., and Dick J.E. A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature 445 (2007) 106-110
-
(2007)
Nature
, vol.445
, pp. 106-110
-
-
O'Brien, C.A.1
Pollett, A.2
Gallinger, S.3
Dick, J.E.4
-
156
-
-
20444397431
-
Identification of bronchioalveolar stem cells in normal lung and lung cancer
-
Kim C.F., Jackson E.L., Woolfenden A.E., Lawrence S., Babar I., Vogel S., Crowley D., Bronson R.T., and Jacks T. Identification of bronchioalveolar stem cells in normal lung and lung cancer. Cell 121 (2005) 823-835
-
(2005)
Cell
, vol.121
, pp. 823-835
-
-
Kim, C.F.1
Jackson, E.L.2
Woolfenden, A.E.3
Lawrence, S.4
Babar, I.5
Vogel, S.6
Crowley, D.7
Bronson, R.T.8
Jacks, T.9
-
157
-
-
28244472369
-
Prospective identification of tumorigenic prostate cancer stem cells
-
Collins A.T., Berry P.A., Hyde C., Stower M.J., and Maitland N.J. Prospective identification of tumorigenic prostate cancer stem cells. Cancer Research 65 (2005) 10946-10951
-
(2005)
Cancer Research
, vol.65
, pp. 10946-10951
-
-
Collins, A.T.1
Berry, P.A.2
Hyde, C.3
Stower, M.J.4
Maitland, N.J.5
-
158
-
-
0030789242
-
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
-
Bonnet D., and Dick J.E. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nature Medicine 3 (1997) 730-737
-
(1997)
Nature Medicine
, vol.3
, pp. 730-737
-
-
Bonnet, D.1
Dick, J.E.2
-
159
-
-
9244241576
-
Identification of human brain tumour initiating cells
-
Singh S.K., Hawkins C., Clarke I.D., Squire J.A., Bayani J., Hide T., Henkelman R.M., Cusimano M.D., and Dirks P.B. Identification of human brain tumour initiating cells. Nature 432 (2004) 396-401
-
(2004)
Nature
, vol.432
, pp. 396-401
-
-
Singh, S.K.1
Hawkins, C.2
Clarke, I.D.3
Squire, J.A.4
Bayani, J.5
Hide, T.6
Henkelman, R.M.7
Cusimano, M.D.8
Dirks, P.B.9
-
160
-
-
27144557960
-
A tumorigenic subpopulation with stem cell properties in melanomas
-
Fang D., Nguyen T.K., Leishear K., Finko R., Kulp A.N., Hotz S., Van Belle P.A., Xu X., Elder D.E., and Herlyn M. A tumorigenic subpopulation with stem cell properties in melanomas. Cancer Research 65 (2005) 9328-9337
-
(2005)
Cancer Research
, vol.65
, pp. 9328-9337
-
-
Fang, D.1
Nguyen, T.K.2
Leishear, K.3
Finko, R.4
Kulp, A.N.5
Hotz, S.6
Van Belle, P.A.7
Xu, X.8
Elder, D.E.9
Herlyn, M.10
-
161
-
-
33847052127
-
Identification of pancreatic cancer stem cells
-
Li C., Heidt D.G., Dalerba P., Burant C.F., Zhang L., Adsay V., Wicha M., Clarke M.F., and Simeone D.M. Identification of pancreatic cancer stem cells. Cancer Research 67 (2007) 1030-1037
-
(2007)
Cancer Research
, vol.67
, pp. 1030-1037
-
-
Li, C.1
Heidt, D.G.2
Dalerba, P.3
Burant, C.F.4
Zhang, L.5
Adsay, V.6
Wicha, M.7
Clarke, M.F.8
Simeone, D.M.9
-
162
-
-
33846095137
-
Identification and expansion of human colon-cancer-initiating cells
-
Ricci-Vitiani L., Lombardi D.G., Pilozzi E., Biffoni M., Todaro M., Peschle C., and De Maria R. Identification and expansion of human colon-cancer-initiating cells. Nature 445 (2007) 111-115
-
(2007)
Nature
, vol.445
, pp. 111-115
-
-
Ricci-Vitiani, L.1
Lombardi, D.G.2
Pilozzi, E.3
Biffoni, M.4
Todaro, M.5
Peschle, C.6
De Maria, R.7
-
163
-
-
33750313208
-
Cancer stem cells - perspectives on current status and future directions: AACR workshop on cancer stem cells
-
Clarke M.F., Dick J.E., Dirks P.B., Eaves C.J., Jamieson C.H., Jones D.L., Visvader J., Weissman I.L., and Wahl G.M. Cancer stem cells - perspectives on current status and future directions: AACR workshop on cancer stem cells. Cancer Research 66 (2006) 9339-9344
-
(2006)
Cancer Research
, vol.66
, pp. 9339-9344
-
-
Clarke, M.F.1
Dick, J.E.2
Dirks, P.B.3
Eaves, C.J.4
Jamieson, C.H.5
Jones, D.L.6
Visvader, J.7
Weissman, I.L.8
Wahl, G.M.9
-
164
-
-
21344454219
-
Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties
-
Ponti D., Costa A., Zaffaroni N., Pratesi G., Petrangolini G., Coradini D., Pilotti S., Pierotti M.A., and Daidone M.G. Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties. Cancer Research 65 (2005) 5506-5511
-
(2005)
Cancer Research
, vol.65
, pp. 5506-5511
-
-
Ponti, D.1
Costa, A.2
Zaffaroni, N.3
Pratesi, G.4
Petrangolini, G.5
Coradini, D.6
Pilotti, S.7
Pierotti, M.A.8
Daidone, M.G.9
-
165
-
-
0037948854
-
In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells
-
Dontu G., Abdallah W.M., Foley J.M., Jackson K.W., Clarke M.F., Kawamura M.J., and Wicha M.S. In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells. Genes and Development 17 (2003) 1253-1270
-
(2003)
Genes and Development
, vol.17
, pp. 1253-1270
-
-
Dontu, G.1
Abdallah, W.M.2
Foley, J.M.3
Jackson, K.W.4
Clarke, M.F.5
Kawamura, M.J.6
Wicha, M.S.7
-
166
-
-
34548569038
-
Enrichment of a population of mammary gland cells that form mammospheres and have in vivo repopulating activity
-
Liao M.J., Zhang C.C., Zhou B., Zimonjic D.B., Mani S.A., Kaba M., Gifford A., Reinhardt F., Popescu N.C., Guo W., Eaton E.N., Lodish H.F., and Weinberg R.A. Enrichment of a population of mammary gland cells that form mammospheres and have in vivo repopulating activity. Cancer Research 67 (2007) 8131-8138
-
(2007)
Cancer Research
, vol.67
, pp. 8131-8138
-
-
Liao, M.J.1
Zhang, C.C.2
Zhou, B.3
Zimonjic, D.B.4
Mani, S.A.5
Kaba, M.6
Gifford, A.7
Reinhardt, F.8
Popescu, N.C.9
Guo, W.10
Eaton, E.N.11
Lodish, H.F.12
Weinberg, R.A.13
-
167
-
-
34547513846
-
The properties of a mammary gland cancer stem cell
-
Zucchi I., Sanzone S., Astigiano S., Pelucchi P., Scotti M., Valsecchi V., Barbieri O., Bertoli G., Albertini A., Reinbold R.A., and Dulbecco R. The properties of a mammary gland cancer stem cell. Proceedings of the National Academy of Sciences of the United States of America 104 (2007) 10476-10481
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, pp. 10476-10481
-
-
Zucchi, I.1
Sanzone, S.2
Astigiano, S.3
Pelucchi, P.4
Scotti, M.5
Valsecchi, V.6
Barbieri, O.7
Bertoli, G.8
Albertini, A.9
Reinbold, R.A.10
Dulbecco, R.11
-
168
-
-
30144432901
-
Purification and unique properties of mammary epithelial stem cells
-
Stingl J., Eirew P., Ricketson I., Shackleton M., Vaillant F., Choi D., Li H.I., and Eaves C.J. Purification and unique properties of mammary epithelial stem cells. Nature 439 (2006) 993-997
-
(2006)
Nature
, vol.439
, pp. 993-997
-
-
Stingl, J.1
Eirew, P.2
Ricketson, I.3
Shackleton, M.4
Vaillant, F.5
Choi, D.6
Li, H.I.7
Eaves, C.J.8
-
169
-
-
30144433093
-
Generation of a functional mammary gland from a single stem cell
-
Shackleton M., Vaillant F., Simpson K.J., Stingl J., Smyth G.K., Asselin-Labat M.L., Wu L., Lindeman G.J., and Visvader J.E. Generation of a functional mammary gland from a single stem cell. Nature 439 (2006) 84-88
-
(2006)
Nature
, vol.439
, pp. 84-88
-
-
Shackleton, M.1
Vaillant, F.2
Simpson, K.J.3
Stingl, J.4
Smyth, G.K.5
Asselin-Labat, M.L.6
Wu, L.7
Lindeman, G.J.8
Visvader, J.E.9
-
170
-
-
38549131901
-
GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model
-
Kouros-Mehr H., Bechis S.K., Slorach E.M., Littlepage L.E., Egeblad M., Ewald A.J., Pai S.Y., Ho I.C., and Werb Z. GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model. Cancer Cell 13 (2008) 141-152
-
(2008)
Cancer Cell
, vol.13
, pp. 141-152
-
-
Kouros-Mehr, H.1
Bechis, S.K.2
Slorach, E.M.3
Littlepage, L.E.4
Egeblad, M.5
Ewald, A.J.6
Pai, S.Y.7
Ho, I.C.8
Werb, Z.9
-
171
-
-
49649085001
-
Identification of tumor-initiating cells in a p53-null mouse model of breast cancer
-
Zhang M., Behbod F., Atkinson R.L., Landis M.D., Kittrell F., Edwards D., Medina D., Tsimelzon A., Hilsenbeck S., Green J.E., Michalowska A.M., and Rosen J.M. Identification of tumor-initiating cells in a p53-null mouse model of breast cancer. Cancer Research 68 (2008) 4674-4682
-
(2008)
Cancer Research
, vol.68
, pp. 4674-4682
-
-
Zhang, M.1
Behbod, F.2
Atkinson, R.L.3
Landis, M.D.4
Kittrell, F.5
Edwards, D.6
Medina, D.7
Tsimelzon, A.8
Hilsenbeck, S.9
Green, J.E.10
Michalowska, A.M.11
Rosen, J.M.12
-
172
-
-
44849143103
-
Cancer stem cells contribute to cisplatin resistance in Brca1/p53-mediated mouse mammary tumors
-
Shafee N., Smith C.R., Wei S., Kim Y., Mills G.B., Hortobagyi G.N., Stanbridge E.J., and Lee E.Y. Cancer stem cells contribute to cisplatin resistance in Brca1/p53-mediated mouse mammary tumors. Cancer Research 68 (2008) 3243-3250
-
(2008)
Cancer Research
, vol.68
, pp. 3243-3250
-
-
Shafee, N.1
Smith, C.R.2
Wei, S.3
Kim, Y.4
Mills, G.B.5
Hortobagyi, G.N.6
Stanbridge, E.J.7
Lee, E.Y.8
-
173
-
-
48849089827
-
FERM control of FAK function: implications for cancer therapy
-
Lim S.T., Mikolon D., and Stupack D.G. FERM control of FAK function: implications for cancer therapy. Cell Cycle 7 (2008) 2306-2314
-
(2008)
Cell Cycle
, vol.7
, pp. 2306-2314
-
-
Lim, S.T.1
Mikolon, D.2
Stupack, D.G.3
-
174
-
-
38949089708
-
Focal adhesion kinase: targeting adhesion signaling pathways for therapeutic intervention
-
Parsons J.T., Slack-Davis J., Tilghman R., and Roberts W.G. Focal adhesion kinase: targeting adhesion signaling pathways for therapeutic intervention. Clinical Cancer Research 14 (2008) 627-632
-
(2008)
Clinical Cancer Research
, vol.14
, pp. 627-632
-
-
Parsons, J.T.1
Slack-Davis, J.2
Tilghman, R.3
Roberts, W.G.4
|