-
1
-
-
0030045346
-
Cell migration: A physically integrated molecular process
-
Lauffenburger, D. A. & Horwitz, A. F. Cell migration: A physically integrated molecular process. Cell 84, 359-369 (1996).
-
(1996)
Cell
, vol.84
, pp. 359-369
-
-
Lauffenburger, D.A.1
Horwitz, A.F.2
-
2
-
-
0036222784
-
Adhesion assembly, disassembly and turnover in migrating cells - Over and over and over again
-
Webb, D. J., Parsons, J. T. & Horwitz, A. F. Adhesion assembly, disassembly and turnover in migrating cells - over and over and over again. Nature Cell Biol. 4, E97-E100 (2002).
-
(2002)
Nature Cell Biol.
, vol.4
-
-
Webb, D.J.1
Parsons, J.T.2
Horwitz, A.F.3
-
3
-
-
0029120440
-
Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice
-
Ilic, D. et al. Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice. Nature 377, 539-544 (1995).
-
(1995)
Nature
, vol.377
, pp. 539-544
-
-
Ilic, D.1
-
4
-
-
0033522510
-
Src family kinases are required for integrin but not PDGFR signal transduction
-
Klinghoffer, R. A., Sachsenmaier, C., Cooper, J. A. & Soriano, P. Src family kinases are required for integrin but not PDGFR signal transduction. EMBO J. 18, 2459-2471 (1999).
-
(1999)
EMBO J.
, vol.18
, pp. 2459-2471
-
-
Klinghoffer, R.A.1
Sachsenmaier, C.2
Cooper, J.A.3
Soriano, P.4
-
5
-
-
0032472411
-
The catalytic activity of Src is dispensable for translocation to focal adhesions but controls the turnover of these structures during cell motility
-
Fincham, V. J. & Frame, M. C. The catalytic activity of Src is dispensable for translocation to focal adhesions but controls the turnover of these structures during cell motility. EMBO J. 17, 81-92 (1998).
-
(1998)
EMBO J.
, vol.17
, pp. 81-92
-
-
Fincham, V.J.1
Frame, M.C.2
-
6
-
-
3543036342
-
Protein-tyrosine phosphatase Shp-2 regulates cell spreading, migration, and focal adhesion
-
Yu, D.-H., Qu, C.-K., Henegariu, O., Lu, X. & Feng, G.-S. Protein-tyrosine phosphatase Shp-2 regulates cell spreading, migration, and focal adhesion. J. Biol. Chem. 273, 21125-21131 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 21125-21131
-
-
Yu, D.-H.1
Qu, C.-K.2
Henegariu, O.3
Lu, X.4
Feng, G.-S.5
-
7
-
-
0345593816
-
Protein tyrosine phosphatase-PEST regulates focal adhesion disassembly, migration, and cytokinesis in fibroblasts
-
Angers-Loustau, A. et al. Protein tyrosine phosphatase-PEST regulates focal adhesion disassembly, migration, and cytokinesis in fibroblasts. J. Cell Biol. 144, 1019-1031 (1999).
-
(1999)
J. Cell Biol.
, vol.144
, pp. 1019-1031
-
-
Angers-Loustau, A.1
-
8
-
-
0029166094
-
Characterization of tyrosine phosphorylation of paxillin in vitro by focal adhesion kinase
-
Bellis, S. L., Miller, J. T. & Turner, C. E. Characterization of tyrosine phosphorylation of paxillin in vitro by focal adhesion kinase. J. Biol. Chem. 270, 17437-17441 (1995).
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 17437-17441
-
-
Bellis, S.L.1
Miller, J.T.2
Turner, C.E.3
-
9
-
-
0028986116
-
pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk
-
Schaller, M. D. & Parsons, J. T. pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk. Mol. Cell. Biol. 15, 2635-2645 (1995).
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 2635-2645
-
-
Schaller, M.D.1
Parsons, J.T.2
-
11
-
-
0036142219
-
The adaptor protein paxillin is essential for normal development in the mouse and is a critical transducer of fibronectin signaling
-
Hagel, M. et al. The adaptor protein paxillin is essential for normal development in the mouse and is a critical transducer of fibronectin signaling. Mol. Cell. Biol. 22, 901-915 (2002).
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 901-915
-
-
Hagel, M.1
-
12
-
-
0033584466
-
p130(Cas), an assembling molecule of actin filaments, promotes cell movement, cell migration, and cell spreading in fibroblasts
-
Honda, H., Nakamoto, T., Sakai, R. & Hirai, H. p130(Cas), an assembling molecule of actin filaments, promotes cell movement, cell migration, and cell spreading in fibroblasts. Biochem. Biophys. Res. Commun. 262, 25-30 (1999).
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.262
, pp. 25-30
-
-
Honda, H.1
Nakamoto, T.2
Sakai, R.3
Hirai, H.4
-
14
-
-
0035954424
-
Differential dynamics of α5 integrin, paxillin, and α-actinin during formation and disassembly of adhesions in migrating cells
-
Laukaitis, C. M., Webb, D. J., Donais, K. & Horwitz, A. F. Differential dynamics of α5 integrin, paxillin, and α -actinin during formation and disassembly of adhesions in migrating cells. J. Cell Biol. 153, 1427-1440 (2001).
-
(2001)
J. Cell Biol.
, vol.153
, pp. 1427-1440
-
-
Laukaitis, C.M.1
Webb, D.J.2
Donais, K.3
Horwitz, A.F.4
-
15
-
-
0028350859
-
FAK, directs SH2-dependent binding of pp60src
-
FAK, directs SH2-dependent binding of pp60src. Mol. Cell. Biol. 14, 1680-1688 (1994).
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 1680-1688
-
-
Schaller, M.D.1
-
16
-
-
0029979722
-
Phosphorylation of tyrosine 397 in focal adhesion kinase is required for binding phosphatidylinositol 3-kinase
-
Chen, H.-C., Appeddu, P. A., Isoda, H. & Guan, J.-L. Phosphorylation of tyrosine 397 in focal adhesion kinase is required for binding phosphatidylinositol 3-kinase. J. Biol. Chem. 271, 26329-26334 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 26329-26334
-
-
Chen, H.-C.1
Appeddu, P.A.2
Isoda, H.3
Guan, J.-L.4
-
17
-
-
0032894567
-
Signaling through focal adhesion kinase
-
Schlaepfer, D. D., Hauck, C. R. & Sieg, D. J. Signaling through focal adhesion kinase. Prog. Biophys. Mol. Biol. 71, 435-478 (1999).
-
(1999)
Prog. Biophys. Mol. Biol.
, vol.71
, pp. 435-478
-
-
Schlaepfer, D.D.1
Hauck, C.R.2
Sieg, D.J.3
-
18
-
-
0029664531
-
Introduction of p130cas signaling complex formation upon integrin-mediated cell adhesion: A role for Src family kinases
-
Vuori, K., Hirai, H., Aizawa, S. & Ruoslahti, E. Introduction of p130cas signaling complex formation upon integrin-mediated cell adhesion: A role for Src family kinases. Mol. Cell. Biol. 16, 2606-2613 (1996).
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 2606-2613
-
-
Vuori, K.1
Hirai, H.2
Aizawa, S.3
Ruoslahti, E.4
-
19
-
-
0033666291
-
Paxillin and focal adhesion signalling
-
Turner, C. E. Paxillin and focal adhesion signalling. Nature Cell Biol. 2, E231-E236 (2000).
-
(2000)
Nature Cell Biol.
, vol.2
-
-
Turner, C.E.1
-
20
-
-
0033577810
-
Paxillin LD4 motif binds PAK and PIX through a novel 95-kD ankryin repeat, ARF-GAP protein: A role in cytoskeletal remodeling
-
Turner, C. E. et al. Paxillin LD4 motif binds PAK and PIX through a novel 95-kD ankryin repeat, ARF-GAP protein: A role in cytoskeletal remodeling. J. Cell Biol. 145, 851-863 (1999).
-
(1999)
J. Cell Biol.
, vol.145
, pp. 851-863
-
-
Turner, C.E.1
-
21
-
-
0029827130
-
Identification of LIM3 as the principal determinant of paxillin focal adhesion localization and characterization of a novel motif on paxillin directing vinculin and focal adhesion kinase binding
-
Brown, M. C., Perrotta, J. A. & Turner, C. E. Identification of LIM3 as the principal determinant of paxillin focal adhesion localization and characterization of a novel motif on paxillin directing vinculin and focal adhesion kinase binding. J. Cell Biol. 135, 1109-1123 (1996).
-
(1996)
J. Cell Biol.
, vol.135
, pp. 1109-1123
-
-
Brown, M.C.1
Perrotta, J.A.2
Turner, C.E.3
-
22
-
-
0033579448
-
The role of focal adhesion kinase binding in the regulation of tyrosine phosphorylation of paxillin
-
Thomas, J. W. et al. The role of focal adhesion kinase binding in the regulation of tyrosine phosphorylation of paxillin. J. Biol. Chem. 274, 36684-36692 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 36684-36692
-
-
Thomas, J.W.1
-
23
-
-
0026445719
-
FAK accompanies cell adhesion to extracellular matrix: A role in cytoskeletal assembly
-
FAK accompanies cell adhesion to extracellular matrix: A role in cytoskeletal assembly. J. Cell Biol. 119, 893-903 (1992).
-
(1992)
J. Cell Biol.
, vol.119
, pp. 893-903
-
-
Burridge, K.1
Turner, C.E.2
Romer, L.H.3
-
24
-
-
0034610997
-
Phosphorylation of tyrosine residues 31 and 118 on paxillin regulates cell migration through an association with CRK in NBT-II cells
-
Petit, V. et al. Phosphorylation of tyrosine residues 31 and 118 on paxillin regulates cell migration through an association with CRK in NBT-II cells. J. Cell Biol. 148, 957-969 (2000).
-
(2000)
J. Cell Biol.
, vol.148
, pp. 957-969
-
-
Petit, V.1
-
25
-
-
0034644603
-
Localized Rac activation dynamics visualized in living cells
-
Kraynov, V. S. et al. Localized Rac activation dynamics visualized in living cells. Science 290, 333-337 (2000).
-
(2000)
Science
, vol.290
, pp. 333-337
-
-
Kraynov, V.S.1
-
26
-
-
0034865456
-
Rho GTPases and cell migration
-
Ridley, A. J. Rho GTPases and cell migration. J. Cell Sci. 114, 2713-2722 (2001).
-
(2001)
J. Cell Sci.
, vol.114
, pp. 2713-2722
-
-
Ridley, A.J.1
-
27
-
-
0344845048
-
Phosphorylation-dependent paxillin-ERK association mediates hepatocyte growth factor-stimulated epithelial morphogenesis
-
Ishibe, S., Joly, D., Zhu, X. & Cantley, L. G. Phosphorylation-dependent paxillin-ERK association mediates hepatocyte growth factor-stimulated epithelial morphogenesis. Mol. Cell 12, 1275-1285 (2003).
-
(2003)
Mol. Cell
, vol.12
, pp. 1275-1285
-
-
Ishibe, S.1
Joly, D.2
Zhu, X.3
Cantley, L.G.4
-
28
-
-
0042672912
-
PAK1 phosphorylation of MEK1 regulates fibronectin-stimulated MAPK activation
-
Slack-Davis, J. K. et al. PAK1 phosphorylation of MEK1 regulates fibronectin-stimulated MAPK activation. J. Cell Biol. 162, 281-291 (2003).
-
(2003)
J. Cell Biol.
, vol.162
, pp. 281-291
-
-
Slack-Davis, J.K.1
-
29
-
-
0030931217
-
Regulation of cell motility by migoten-activated protein kinase
-
Klemke, R. L. et al. Regulation of cell motility by migoten-activated protein kinase. J. Cell Biol. 137, 481-492 (1997).
-
(1997)
J. Cell Biol.
, vol.137
, pp. 481-492
-
-
Klemke, R.L.1
-
30
-
-
0034755942
-
Molecular complexity and dynamics of cell-matrix adhesions
-
Zamir, E. & Geiger, B. Molecular complexity and dynamics of cell-matrix adhesions. J. Cell Sci. 114, 3583-3590 (2001).
-
(2001)
J. Cell Sci.
, vol.114
, pp. 3583-3590
-
-
Zamir, E.1
Geiger, B.2
-
31
-
-
0034660524
-
Active ERK/MAP kinase is targeted to newly forming cell-matrix adhesions by integrin engagement and v-Src
-
Fincham, V., James, M., Frame, M. & Winder, S. Active ERK/MAP kinase is targeted to newly forming cell-matrix adhesions by integrin engagement and v-Src. EMBO J. 19, 2911-2923 (2000).
-
(2000)
EMBO J.
, vol.19
, pp. 2911-2923
-
-
Fincham, V.1
James, M.2
Frame, M.3
Winder, S.4
-
32
-
-
0028841220
-
Tyrosine phosphorylation and cytosketal tension regulate the release of fibroblast adhesions
-
Crowley, E. & Horwitz, A. F. Tyrosine phosphorylation and cytosketal tension regulate the release of fibroblast adhesions. J. Cell Biol. 131, 525-537 (1995).
-
(1995)
J. Cell Biol.
, vol.131
, pp. 525-537
-
-
Crowley, E.1
Horwitz, A.F.2
-
33
-
-
0033731010
-
Focal adhesion kinase suppresses Rho activity to promote focal adhesion turnover
-
Ren, X. D. et al. Focal adhesion kinase suppresses Rho activity to promote focal adhesion turnover. J. Cell Sci. 113, 3673-3678 (2000).
-
(2000)
J. Cell Sci.
, vol.113
, pp. 3673-3678
-
-
Ren, X.D.1
-
34
-
-
0037072731
-
Roles of Rho-associated kinase and myosin light chain kinase in morphological and migratory defects of focal adhesion kinase-null cells
-
Chen, B.-C., Tzen, J. T., Bresnick, A. R. & Chen, H.-C. Roles of Rho-associated kinase and myosin light chain kinase in morphological and migratory defects of focal adhesion kinase-null cells. J. Biol. Chem. 277, 33857-33863 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 33857-33863
-
-
Chen, B.-C.1
Tzen, J.T.2
Bresnick, A.R.3
Chen, H.-C.4
-
35
-
-
0041924982
-
A novel role for FAK as a protease-targeting adaptor protein: Regulation by p42 ERK and Src
-
Carragher, N. O., Westhoff, M. A., Fincham, V. J., Schaller, M. D. & Frame, M. C. A novel role for FAK as a protease-targeting adaptor protein: Regulation by p42 ERK and Src. Curr. Biol. 13, 1442-1450 (2003).
-
(2003)
Curr. Biol.
, vol.13
, pp. 1442-1450
-
-
Carragher, N.O.1
Westhoff, M.A.2
Fincham, V.J.3
Schaller, M.D.4
Frame, M.C.5
-
36
-
-
0029820264
-
Modulation of cell migration by integrin-mediated cytoskeletal linkages and ligand-binding affinity
-
Huttenlocher, A., Ginsberg, M. H. & Horwitz, A. F. Modulation of cell migration by integrin-mediated cytoskeletal linkages and ligand-binding affinity. J. Cell Biol. 134, 1551-1562 (1996).
-
(1996)
J. Cell Biol.
, vol.134
, pp. 1551-1562
-
-
Huttenlocher, A.1
Ginsberg, M.H.2
Horwitz, A.F.3
-
37
-
-
0035930548
-
Reduced cell migration and disruption of the actin cytoskeleton in calpain-deficient embryonic fibroblasts
-
Dourdin, N. et al. Reduced cell migration and disruption of the actin cytoskeleton in calpain-deficient embryonic fibroblasts. J. Biol. Chem. 276, 48382-48388 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 48382-48388
-
-
Dourdin, N.1
-
38
-
-
0035800777
-
The cytoskeletal/non-muscle isoform of α-actinin is phosphorylated on its actin-binding domain by focal adhesion kinase
-
Izaguirre, G. et al. The cytoskeletal/non-muscle isoform of α-actinin is phosphorylated on its actin-binding domain by focal adhesion kinase. J. Biol. Chem. 276, 28676-28685 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 28676-28685
-
-
Izaguirre, G.1
-
39
-
-
0029153801
-
c-Src regulates the simultaneous rearrangement of actin cytoskeleton, p190RhoGAP, and p120RasGAP following epidermal growth factor stimulation
-
Chang, J. H., Settleman, J. & Parsons, S. J. c-Src regulates the simultaneous rearrangement of actin cytoskeleton, p190RhoGAP, and p120RasGAP following epidermal growth factor stimulation. J. Cell Biol. 130, 355-368 (1995).
-
(1995)
J. Cell Biol.
, vol.130
, pp. 355-368
-
-
Chang, J.H.1
Settleman, J.2
Parsons, S.J.3
-
40
-
-
0029164688
-
A proline-rich sequence unique to MEK1 and MEK2 is required for raf binding and regulates MEK function
-
Catling, A. D., Schaeffer, H. J., Reuter, C. W., Reddy, G. R. & Weber, M. J. A proline-rich sequence unique to MEK1 and MEK2 is required for raf binding and regulates MEK function. Mol. Cell. Biol. 15, 5214-5225 (1995).
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 5214-5225
-
-
Catling, A.D.1
Schaeffer, H.J.2
Reuter, C.W.3
Reddy, G.R.4
Weber, M.J.5
-
41
-
-
0030000154
-
Integrin dynamics on the tail region of migrating fibroblasts
-
Palecek, S. P., Schmidt, C. E., Lauffenburger, D. A. & Horwitz, A. F. Integrin dynamics on the tail region of migrating fibroblasts. J. Cell Sci. 109, 941-952 (1996).
-
(1996)
J. Cell Sci.
, vol.109
, pp. 941-952
-
-
Palecek, S.P.1
Schmidt, C.E.2
Lauffenburger, D.A.3
Horwitz, A.F.4
|