FRNK blocks v-Src-stimulated invasion and experimental metastases without effects on cell motility or growth

EMBO Journal

Volumn 21, Issue 23, 2002, Pages 6289-6302

  Hauck, Christof R ^a,b   Hsia, Datsun A ^a   Puente, Xose S ^a   Cheresh, David A ^a   Schlaepfer, David D ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Cell invasion; FAK; Matrix; Metalloproteinase; Metastasis; Src

Indexed keywords

AGAR; FOCAL ADHESION KINASE; GELATINASE A; MATRIGEL; MESSENGER RNA; PROTEIN FRNK; PROTEIN KINASE B; PROTEIN KINASE P60; PROTEIN P130; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CELL GROWTH; CELL INVASION; CELL MOTILITY; CELL TRANSFORMATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME LOCALIZATION; ENZYME REGULATION; GENE DISRUPTION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; METASTASIS; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; WILD TYPE;

3T3 CELLS; ANIMALS; CELL MOVEMENT; LUNG NEOPLASMS; MATRIX METALLOPROTEINASE 2; MICE; MICE, NUDE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 8; MITOGEN-ACTIVATED PROTEIN KINASES; ONCOGENE PROTEIN PP60(V-SRC); PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

ANIMALIA; MUS MUSCULUS;

EID: 0037011055     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdf631     Document Type: Article

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