Intrinsic FAK activity and Y925 phosphorylation facilitate an angiogenic switch in tumors

Oncogene

Volumn 25, Issue 44, 2006, Pages 5969-5984

  Mitra, S K ^a   Mikolon, D ^b   Molina, J E ^a   Hsia, D A ^a,d   Hanson, D A ^a   Chi, A ^a   Lim, S T ^a   Bernard Trifilo, J A ^a   Ilic, D ^c   Stupack, D G ^b   Cheresh, D A ^b   Schlaepfer, D D ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c StemLifeLine Inc   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

angiogenesis; FAK; FRNK; Tumor growth; VEGF

Indexed keywords

FOCAL ADHESION KINASE; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; STEROID RECEPTOR COACTIVATOR 1; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CARCINOGENESIS; BREAST CARCINOMA; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME DEFECT; ENZYME PHOSPHORYLATION; ENZYME SUBUNIT; EXPERIMENTATION; FIBROBLAST; GENE REPRESSION; GENETIC LINKAGE; HUMAN; HUMAN CELL; MALE; MOUSE; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TUMOR GROWTH; TUMOR VASCULARIZATION;

ANIMALS; BREAST NEOPLASMS; CARCINOMA; CELL LINE, TRANSFORMED; CELL LINE, TUMOR; CELLS, CULTURED; CLONE CELLS; FEMALE; FOCAL ADHESION PROTEIN-TYROSINE KINASES; HUMANS; MAMMARY NEOPLASMS, ANIMAL; MICE; MICE, INBRED BALB C; MICE, NUDE; NEOVASCULARIZATION, PATHOLOGIC; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; SIGNAL TRANSDUCTION; TYROSINE;

EID: 33749188459     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1209588     Document Type: Article

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