메뉴 건너뛰기




Volumn 18, Issue 10, 2005, Pages 1289-1294

High focal adhesion kinase expression in invasive breast carcinomas is associated with an aggressive phenotype

Author keywords

Breast cancer; Focal adhesion kinase; Immunohistochemistry

Indexed keywords

ANTIBODY; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; FOCAL ADHESION KINASE; FORMALDEHYDE; PARAFFIN; PROGESTERONE RECEPTOR;

EID: 24944531575     PISSN: 08933952     EISSN: None     Source Type: Journal    
DOI: 10.1038/modpathol.3800424     Document Type: Article
Times cited : (156)

References (39)
  • 1
    • 2342512255 scopus 로고    scopus 로고
    • Therapeutically targeted anticancer agents: Inhibitors of receptor tyrosine kinases
    • Garcia-Echeverria C, Fabbro D. Therapeutically targeted anticancer agents: inhibitors of receptor tyrosine kinases. Mini Rev Med Chem 2004;4:273-283.
    • (2004) Mini Rev Med Chem , vol.4 , pp. 273-283
    • Garcia-Echeverria, C.1    Fabbro, D.2
  • 2
    • 1242338152 scopus 로고    scopus 로고
    • The HER receptor family: A rich target for therapeutic development
    • Mass RD. The HER receptor family: a rich target for therapeutic development. Int J Radiat Oncol Biol Phys 2004;58:932-940.
    • (2004) Int J Radiat Oncol Biol Phys , vol.58 , pp. 932-940
    • Mass, R.D.1
  • 3
    • 0027055575 scopus 로고
    • Cell adhesion or integrin clustering increases phosphorylation of a focal adhesion-associated tyrosine kinase
    • Kornberg L, Earp HS, Parsons JT, et al. Cell adhesion or integrin clustering increases phosphorylation of a focal adhesion-associated tyrosine kinase. J Biol Chem 1992;267:23439-23442.
    • (1992) J Biol Chem , vol.267 , pp. 23439-23442
    • Kornberg, L.1    Earp, H.S.2    Parsons, J.T.3
  • 4
    • 0026497659 scopus 로고
    • Integrin-dependent phosphorylation and activation of the protein tyrosine kinase pp125FAK in platelets
    • Lipfert L, Haimovich B, Schaller MD, et al. Integrin-dependent phosphorylation and activation of the protein tyrosine kinase pp125FAK in platelets. J Cell Biol 1992;119:905-912.
    • (1992) J Cell Biol , vol.119 , pp. 905-912
    • Lipfert, L.1    Haimovich, B.2    Schaller, M.D.3
  • 5
    • 0028609382 scopus 로고
    • Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase
    • Schlaepfer DD, Hanks SK, Hunter T, et al. Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase. Nature 1994;372:786-791.
    • (1994) Nature , vol.372 , pp. 786-791
    • Schlaepfer, D.D.1    Hanks, S.K.2    Hunter, T.3
  • 6
    • 0030772959 scopus 로고    scopus 로고
    • Role of focal adhesion kinase in integrin signaling
    • Guan JL. Role of focal adhesion kinase in integrin signaling. Int J Biochem Cell Biol 1997;29:1085-1096.
    • (1997) Int J Biochem Cell Biol , vol.29 , pp. 1085-1096
    • Guan, J.L.1
  • 7
    • 0029948080 scopus 로고    scopus 로고
    • Stimulation of cell migration by overexpression of focal adhesion kinase and its association with Src and Fyn
    • Cary LA, Chang JF, Guan JL. Stimulation of cell migration by overexpression of focal adhesion kinase and its association with Src and Fyn. J Cell Sci 1996;109:1787-1794.
    • (1996) J Cell Sci , vol.109 , pp. 1787-1794
    • Cary, L.A.1    Chang, J.F.2    Guan, J.L.3
  • 8
    • 0029848157 scopus 로고    scopus 로고
    • Attenuation of the expression of the focal adhesion kinase induces apoptosis in tumor cells
    • Xu LH, Owens LV, Sturge GC, et al. Attenuation of the expression of the focal adhesion kinase induces apoptosis in tumor cells. Cell Growth Differ 1996;7:413-418.
    • (1996) Cell Growth Differ , vol.7 , pp. 413-418
    • Xu, L.H.1    Owens, L.V.2    Sturge, G.C.3
  • 9
    • 0029739950 scopus 로고    scopus 로고
    • Control of adhesion-dependent cell survival by focal adhesion kinase
    • Firsch SM, Vuori K, Ruoslahti E, et al. Control of adhesion-dependent cell survival by focal adhesion kinase. J Cell Biol 1996;134:793-799.
    • (1996) J Cell Biol , vol.134 , pp. 793-799
    • Firsch, S.M.1    Vuori, K.2    Ruoslahti, E.3
  • 10
    • 0030300180 scopus 로고    scopus 로고
    • Inhibition of pp125FAK in cultures fibroblasts results in apoptosis
    • Hungerford JE, Compton MT, Matter ML, et al. Inhibition of pp125FAK in cultures fibroblasts results in apoptosis. J Cell Biol 1996;135:1383-1390.
    • (1996) J Cell Biol , vol.135 , pp. 1383-1390
    • Hungerford, J.E.1    Compton, M.T.2    Matter, M.L.3
  • 11
    • 0026612521 scopus 로고
    • pp125fak a structurally distinctive protein-tyrosine kinase associated with focal adhesions
    • USA
    • Schaller MD, Borgman CA, Cobb BS, et al. pp125fak a structurally distinctive protein-tyrosine kinase associated with focal adhesions. Proc Natl Acad Sci USA 1992;89:5192-5196.
    • (1992) Proc Natl Acad Sci , vol.89 , pp. 5192-5196
    • Schaller, M.D.1    Borgman, C.A.2    Cobb, B.S.3
  • 12
    • 0028367719 scopus 로고
    • Expression of growth factor receptors, the focal adhesion kinase, and other tyrosine kinases in human soft tissue tumors
    • Weiner TM, Liu ET, Craven RJ, et al. Expression of growth factor receptors, the focal adhesion kinase, and other tyrosine kinases in human soft tissue tumors. Ann Surg Oncol 1994;1:18-27.
    • (1994) Ann Surg Oncol , vol.1 , pp. 18-27
    • Weiner, T.M.1    Liu, E.T.2    Craven, R.J.3
  • 13
    • 0029039421 scopus 로고
    • Overexpression of the focal adhesion kinase (p125FAK) in invasive human tumors
    • Owens LV, Xu L, Craven RJ, et al. Overexpression of the focal adhesion kinase (p125FAK) in invasive human tumors. Cancer Res 1995;55:2752-2755.
    • (1995) Cancer Res , vol.55 , pp. 2752-2755
    • Owens, L.V.1    Xu, L.2    Craven, R.J.3
  • 14
    • 0034044795 scopus 로고    scopus 로고
    • Immunohistochemical analyses of focal adhesion kinase expression in benign and malignant human breast and colon tissues: Correlation with preinvasive and invasive phenotypes
    • Cance WG, Harris JE, Iacocca MV, et al. Immunohistochemical analyses of focal adhesion kinase expression in benign and malignant human breast and colon tissues: correlation with preinvasive and invasive phenotypes. Clin Cancer Res 2000;6:2417-2423.
    • (2000) Clin Cancer Res , vol.6 , pp. 2417-2423
    • Cance, W.G.1    Harris, J.E.2    Iacocca, M.V.3
  • 15
    • 9644275426 scopus 로고    scopus 로고
    • Upregulation of focal adhesion kinase (FAK) expression in ductal carcinoma in situ (DCIS) is an early event in breast tumorigenesis
    • Lightfoot Jr M, Lark A, Livasy CA, et al. Upregulation of focal adhesion kinase (FAK) expression in ductal carcinoma in situ (DCIS) is an early event in breast tumorigenesis. Breast Cancer Res Treat 2004;88:109-116.
    • (2004) Breast Cancer Res Treat , vol.88 , pp. 109-116
    • Lightfoot Jr., M.1    Lark, A.2    Livasy, C.A.3
  • 16
    • 0037343388 scopus 로고    scopus 로고
    • Focal adhesion kinase as a marker of malignant phenotype in breast and cervical carcinomas
    • Oktay MH, Oktay K, Hamele-Bena D, et al. Focal adhesion kinase as a marker of malignant phenotype in breast and cervical carcinomas. Hum Pathol 2003;34:240-245.
    • (2003) Hum Pathol , vol.34 , pp. 240-245
    • Oktay, M.H.1    Oktay, K.2    Hamele-Bena, D.3
  • 17
    • 0031112814 scopus 로고    scopus 로고
    • Overexpression of focal adhesion kinase (p125FAK) in human colorectal carcinoma liver metastases: Independence from c-src or c-yes activation
    • Han NM, Fleming RY, Curley SA, et al. Overexpression of focal adhesion kinase (p125FAK) in human colorectal carcinoma liver metastases: independence from c-src or c-yes activation. Ann Surg Oncol 1997;4:264-268.
    • (1997) Ann Surg Oncol , vol.4 , pp. 264-268
    • Han, N.M.1    Fleming, R.Y.2    Curley, S.A.3
  • 18
    • 0037237066 scopus 로고    scopus 로고
    • Overexpression of focal adhesion kinase in primary colorectal carcinomas and colorectal liver metastases
    • Lark AL, Livasy CA, Calvo B, et al. Overexpression of focal adhesion kinase in primary colorectal carcinomas and colorectal liver metastases. Clin Cancer Res 2003;9:215-222.
    • (2003) Clin Cancer Res , vol.9 , pp. 215-222
    • Lark, A.L.1    Livasy, C.A.2    Calvo, B.3
  • 19
    • 0029690892 scopus 로고    scopus 로고
    • The focal adhesion kinase as a marker of invasive potential in differentiated human thyroid cancer
    • Owens LV, Xu L, Dent GA, et al. The focal adhesion kinase as a marker of invasive potential in differentiated human thyroid cancer. Ann Surg Oncol 1996;3:100-105.
    • (1996) Ann Surg Oncol , vol.3 , pp. 100-105
    • Owens, L.V.1    Xu, L.2    Dent, G.A.3
  • 20
    • 0033570076 scopus 로고    scopus 로고
    • Overexpression of focal adhesion kinase, a protein tyrosine kinase, in ovarian carcinoma
    • Judson PL, He X, Cance WG, et al. Overexpression of focal adhesion kinase, a protein tyrosine kinase, in ovarian carcinoma. Cancer 1999;86:1551-1556.
    • (1999) Cancer , vol.86 , pp. 1551-1556
    • Judson, P.L.1    He, X.2    Cance, W.G.3
  • 21
    • 0031657454 scopus 로고    scopus 로고
    • Focal adhesion kinase and its potential involvement in tumor invasion and metastasis
    • Kornberg LJ. Focal adhesion kinase and its potential involvement in tumor invasion and metastasis. Head Neck 1998;20:745-752.
    • (1998) Head Neck , vol.20 , pp. 745-752
    • Kornberg, L.J.1
  • 22
    • 0041369959 scopus 로고    scopus 로고
    • FAK overexpression in correlated with tumour invasiveness and lymph node metastasis in oesophageal squamous cell carcinoma
    • Miyazaki T, Kato H, Nakajima M, et al. FAK overexpression in correlated with tumour invasiveness and lymph node metastasis in oesophageal squamous cell carcinoma. Br J Cancer 2003;89:140-145.
    • (2003) Br J Cancer , vol.89 , pp. 140-145
    • Miyazaki, T.1    Kato, H.2    Nakajima, M.3
  • 23
    • 0034730632 scopus 로고    scopus 로고
    • The focal adhesion kinase suppresses transformation-associated, anchorage-independent apoptosis in human breast cancer cells
    • Xu LH, Yang X, Bradham CA, et al. The focal adhesion kinase suppresses transformation-associated, anchorage-independent apoptosis in human breast cancer cells. J Biol Chem 2000;275:30597-30604.
    • (2000) J Biol Chem , vol.275 , pp. 30597-30604
    • Xu, L.H.1    Yang, X.2    Bradham, C.A.3
  • 24
    • 0032547796 scopus 로고    scopus 로고
    • Extracellular matrix survival signals transduced by focal adhesion kinase suppress p53-mediated apoptosis
    • Ilic D, Almeida EAC, Schlaepfer DD, et al. Extracellular matrix survival signals transduced by focal adhesion kinase suppress p53-mediated apoptosis. J Cell Biol 1998;143:547-560.
    • (1998) J Cell Biol , vol.143 , pp. 547-560
    • Ilic, D.1    Almeida, E.A.C.2    Schlaepfer, D.D.3
  • 25
    • 0036531921 scopus 로고    scopus 로고
    • Evalence and spectrum of p53 mutations associated with smoking in breast cancer
    • Conway K, Edmiston SN, Cui L, et al. evalence and spectrum of p53 mutations associated with smoking in breast cancer. Cancer Res 2002;62:1987-1995.
    • (2002) Cancer Res , vol.62 , pp. 1987-1995
    • Conway, K.1    Edmiston, S.N.2    Cui, L.3
  • 26
    • 0037899640 scopus 로고    scopus 로고
    • HER2 codon 655 polymorphism and risk of breast cancer in African Americans and whites
    • Millikan R, Eaton A, Worley K, et al. HER2 codon 655 polymorphism and risk of breast cancer in African Americans and whites. Breast Cancer Res Treat 2003;79:355-364.
    • (2003) Breast Cancer Res Treat , vol.79 , pp. 355-364
    • Millikan, R.1    Eaton, A.2    Worley, K.3
  • 27
    • 0034814266 scopus 로고    scopus 로고
    • Tumor characteristics in African American and white women
    • Furberg H, Millikan R, Dressler L, et al. Tumor characteristics in African American and white women. Breast Cancer Res Treat 2001;68:33-43.
    • (2001) Breast Cancer Res Treat , vol.68 , pp. 33-43
    • Furberg, H.1    Millikan, R.2    Dressler, L.3
  • 28
    • 0033433958 scopus 로고    scopus 로고
    • Policy guidelines for the utilization of formalin-fixed, paraffin-embedded tissue sections: The UNC SPORE experience
    • Dressler LG, Geradts J, Burroughs M, et al. Policy guidelines for the utilization of formalin-fixed, paraffin-embedded tissue sections: the UNC SPORE experience. Breast Cancer Res Treat 1999;58:31-39.
    • (1999) Breast Cancer Res Treat , vol.58 , pp. 31-39
    • Dressler, L.G.1    Geradts, J.2    Burroughs, M.3
  • 29
    • 0028354305 scopus 로고
    • c-erbB-2 expression and response to adjuvant therapy in women with node-positive early breast cancer
    • Muss HB, Thor AD, Berry DA. c-erbB-2 expression and response to adjuvant therapy in women with node-positive early breast cancer. N Engl J Med 1994;330:1260-1266.
    • (1994) N Engl J Med , vol.330 , pp. 1260-1266
    • Muss, H.B.1    Thor, A.D.2    Berry, D.A.3
  • 30
    • 0031903725 scopus 로고    scopus 로고
    • Cigarette smoking, N-acteyltransferases 1 and 2, and breast cancer risk
    • Millikan R, Pittman G, Newman B. Cigarette smoking, N-acteyltransferases 1 and 2, and breast cancer risk. Cancer Epidemiol Biomarkers Prev 1998;7:371-378.
    • (1998) Cancer Epidemiol Biomarkers Prev , vol.7 , pp. 371-378
    • Millikan, R.1    Pittman, G.2    Newman, B.3
  • 32
    • 0022406444 scopus 로고
    • Amplification of a novel v-erbB-related gene in a human mammary carcinoma
    • King CR, Kraus MH, Aaronson SA. Amplification of a novel v-erbB-related gene in a human mammary carcinoma. Science 1985;229:974.
    • (1985) Science , vol.229 , pp. 974
    • King, C.R.1    Kraus, M.H.2    Aaronson, S.A.3
  • 33
    • 37049183697 scopus 로고
    • Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
    • Slamon DJ, Clark GM, Wong SJ, et al. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 1987;235:177-182.
    • (1987) Science , vol.235 , pp. 177-182
    • Slamon, D.J.1    Clark, G.M.2    Wong, S.J.3
  • 34
    • 0024337144 scopus 로고
    • Studies of the HER-2/neu protooncogene in human breast and ovarian cancer
    • Slamon DJ, Godolphin W, Jones LA. Studies of the HER-2/neu protooncogene in human breast and ovarian cancer. Science 1989;244:707-712.
    • (1989) Science , vol.244 , pp. 707-712
    • Slamon, D.J.1    Godolphin, W.2    Jones, L.A.3
  • 35
    • 0038393116 scopus 로고    scopus 로고
    • Heregulin and HER2 signaling selectively activates c-Src phosphorylation at tyrosine 215
    • Vadlamudi RK, Sahin AA, Adam L, et al. Heregulin and HER2 signaling selectively activates c-Src phosphorylation at tyrosine 215. FEBS Lett 2003;543:76-80.
    • (2003) FEBS Lett , vol.543 , pp. 76-80
    • Vadlamudi, R.K.1    Sahin, A.A.2    Adam, L.3
  • 36
    • 0029971297 scopus 로고    scopus 로고
    • A mechanism for regulation of the adhesion-associated protein tyrosine kinase pp125FAK
    • Richardson A, Parson TA. A mechanism for regulation of the adhesion-associated protein tyrosine kinase pp125FAK. Nature 1996;380:538-540.
    • (1996) Nature , vol.380 , pp. 538-540
    • Richardson, A.1    Parson, T.A.2
  • 37
    • 0041426730 scopus 로고    scopus 로고
    • Simultaneous inhibition of focal adhesion kinase and SRC enhances detachment and apoptosis in colon cancer cell lines
    • Golubovskaya VM, Gross S, Kaur AS, et al. Simultaneous inhibition of focal adhesion kinase and SRC enhances detachment and apoptosis in colon cancer cell lines. Mol Cancer Res 2003;10:755-764.
    • (2003) Mol Cancer Res , vol.10 , pp. 755-764
    • Golubovskaya, V.M.1    Gross, S.2    Kaur, A.S.3
  • 38
    • 0038005805 scopus 로고    scopus 로고
    • Focal adhesion kinase N-terminus in breast carcinoma cells induces rounding, detachment and apoptosis
    • Beviglia L, Golubovskaya V, Xu L, et al. Focal adhesion kinase N-terminus in breast carcinoma cells induces rounding, detachment and apoptosis. Biochem J 2003;373:201-210.
    • (2003) Biochem J , vol.373 , pp. 201-210
    • Beviglia, L.1    Golubovskaya, V.2    Xu, L.3
  • 39
    • 2942531163 scopus 로고    scopus 로고
    • Focal adhesion kinase suppresses apoptosis by binding to the death domain of receptor-interacting protein
    • Kurenova E, Xu LH, Yang X, et al. Focal adhesion kinase suppresses apoptosis by binding to the death domain of receptor-interacting protein. Mol Cell Biol 2004;24:4361-4371.
    • (2004) Mol Cell Biol , vol.24 , pp. 4361-4371
    • Kurenova, E.1    Xu, L.H.2    Yang, X.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.