-
1
-
-
2342512255
-
Therapeutically targeted anticancer agents: Inhibitors of receptor tyrosine kinases
-
Garcia-Echeverria C, Fabbro D. Therapeutically targeted anticancer agents: inhibitors of receptor tyrosine kinases. Mini Rev Med Chem 2004;4:273-283.
-
(2004)
Mini Rev Med Chem
, vol.4
, pp. 273-283
-
-
Garcia-Echeverria, C.1
Fabbro, D.2
-
2
-
-
1242338152
-
The HER receptor family: A rich target for therapeutic development
-
Mass RD. The HER receptor family: a rich target for therapeutic development. Int J Radiat Oncol Biol Phys 2004;58:932-940.
-
(2004)
Int J Radiat Oncol Biol Phys
, vol.58
, pp. 932-940
-
-
Mass, R.D.1
-
3
-
-
0027055575
-
Cell adhesion or integrin clustering increases phosphorylation of a focal adhesion-associated tyrosine kinase
-
Kornberg L, Earp HS, Parsons JT, et al. Cell adhesion or integrin clustering increases phosphorylation of a focal adhesion-associated tyrosine kinase. J Biol Chem 1992;267:23439-23442.
-
(1992)
J Biol Chem
, vol.267
, pp. 23439-23442
-
-
Kornberg, L.1
Earp, H.S.2
Parsons, J.T.3
-
4
-
-
0026497659
-
Integrin-dependent phosphorylation and activation of the protein tyrosine kinase pp125FAK in platelets
-
Lipfert L, Haimovich B, Schaller MD, et al. Integrin-dependent phosphorylation and activation of the protein tyrosine kinase pp125FAK in platelets. J Cell Biol 1992;119:905-912.
-
(1992)
J Cell Biol
, vol.119
, pp. 905-912
-
-
Lipfert, L.1
Haimovich, B.2
Schaller, M.D.3
-
5
-
-
0028609382
-
Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase
-
Schlaepfer DD, Hanks SK, Hunter T, et al. Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase. Nature 1994;372:786-791.
-
(1994)
Nature
, vol.372
, pp. 786-791
-
-
Schlaepfer, D.D.1
Hanks, S.K.2
Hunter, T.3
-
6
-
-
0030772959
-
Role of focal adhesion kinase in integrin signaling
-
Guan JL. Role of focal adhesion kinase in integrin signaling. Int J Biochem Cell Biol 1997;29:1085-1096.
-
(1997)
Int J Biochem Cell Biol
, vol.29
, pp. 1085-1096
-
-
Guan, J.L.1
-
7
-
-
0029948080
-
Stimulation of cell migration by overexpression of focal adhesion kinase and its association with Src and Fyn
-
Cary LA, Chang JF, Guan JL. Stimulation of cell migration by overexpression of focal adhesion kinase and its association with Src and Fyn. J Cell Sci 1996;109:1787-1794.
-
(1996)
J Cell Sci
, vol.109
, pp. 1787-1794
-
-
Cary, L.A.1
Chang, J.F.2
Guan, J.L.3
-
8
-
-
0029848157
-
Attenuation of the expression of the focal adhesion kinase induces apoptosis in tumor cells
-
Xu LH, Owens LV, Sturge GC, et al. Attenuation of the expression of the focal adhesion kinase induces apoptosis in tumor cells. Cell Growth Differ 1996;7:413-418.
-
(1996)
Cell Growth Differ
, vol.7
, pp. 413-418
-
-
Xu, L.H.1
Owens, L.V.2
Sturge, G.C.3
-
9
-
-
0029739950
-
Control of adhesion-dependent cell survival by focal adhesion kinase
-
Firsch SM, Vuori K, Ruoslahti E, et al. Control of adhesion-dependent cell survival by focal adhesion kinase. J Cell Biol 1996;134:793-799.
-
(1996)
J Cell Biol
, vol.134
, pp. 793-799
-
-
Firsch, S.M.1
Vuori, K.2
Ruoslahti, E.3
-
10
-
-
0030300180
-
Inhibition of pp125FAK in cultures fibroblasts results in apoptosis
-
Hungerford JE, Compton MT, Matter ML, et al. Inhibition of pp125FAK in cultures fibroblasts results in apoptosis. J Cell Biol 1996;135:1383-1390.
-
(1996)
J Cell Biol
, vol.135
, pp. 1383-1390
-
-
Hungerford, J.E.1
Compton, M.T.2
Matter, M.L.3
-
11
-
-
0026612521
-
pp125fak a structurally distinctive protein-tyrosine kinase associated with focal adhesions
-
USA
-
Schaller MD, Borgman CA, Cobb BS, et al. pp125fak a structurally distinctive protein-tyrosine kinase associated with focal adhesions. Proc Natl Acad Sci USA 1992;89:5192-5196.
-
(1992)
Proc Natl Acad Sci
, vol.89
, pp. 5192-5196
-
-
Schaller, M.D.1
Borgman, C.A.2
Cobb, B.S.3
-
12
-
-
0028367719
-
Expression of growth factor receptors, the focal adhesion kinase, and other tyrosine kinases in human soft tissue tumors
-
Weiner TM, Liu ET, Craven RJ, et al. Expression of growth factor receptors, the focal adhesion kinase, and other tyrosine kinases in human soft tissue tumors. Ann Surg Oncol 1994;1:18-27.
-
(1994)
Ann Surg Oncol
, vol.1
, pp. 18-27
-
-
Weiner, T.M.1
Liu, E.T.2
Craven, R.J.3
-
13
-
-
0029039421
-
Overexpression of the focal adhesion kinase (p125FAK) in invasive human tumors
-
Owens LV, Xu L, Craven RJ, et al. Overexpression of the focal adhesion kinase (p125FAK) in invasive human tumors. Cancer Res 1995;55:2752-2755.
-
(1995)
Cancer Res
, vol.55
, pp. 2752-2755
-
-
Owens, L.V.1
Xu, L.2
Craven, R.J.3
-
14
-
-
0034044795
-
Immunohistochemical analyses of focal adhesion kinase expression in benign and malignant human breast and colon tissues: Correlation with preinvasive and invasive phenotypes
-
Cance WG, Harris JE, Iacocca MV, et al. Immunohistochemical analyses of focal adhesion kinase expression in benign and malignant human breast and colon tissues: correlation with preinvasive and invasive phenotypes. Clin Cancer Res 2000;6:2417-2423.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 2417-2423
-
-
Cance, W.G.1
Harris, J.E.2
Iacocca, M.V.3
-
15
-
-
9644275426
-
Upregulation of focal adhesion kinase (FAK) expression in ductal carcinoma in situ (DCIS) is an early event in breast tumorigenesis
-
Lightfoot Jr M, Lark A, Livasy CA, et al. Upregulation of focal adhesion kinase (FAK) expression in ductal carcinoma in situ (DCIS) is an early event in breast tumorigenesis. Breast Cancer Res Treat 2004;88:109-116.
-
(2004)
Breast Cancer Res Treat
, vol.88
, pp. 109-116
-
-
Lightfoot Jr., M.1
Lark, A.2
Livasy, C.A.3
-
16
-
-
0037343388
-
Focal adhesion kinase as a marker of malignant phenotype in breast and cervical carcinomas
-
Oktay MH, Oktay K, Hamele-Bena D, et al. Focal adhesion kinase as a marker of malignant phenotype in breast and cervical carcinomas. Hum Pathol 2003;34:240-245.
-
(2003)
Hum Pathol
, vol.34
, pp. 240-245
-
-
Oktay, M.H.1
Oktay, K.2
Hamele-Bena, D.3
-
17
-
-
0031112814
-
Overexpression of focal adhesion kinase (p125FAK) in human colorectal carcinoma liver metastases: Independence from c-src or c-yes activation
-
Han NM, Fleming RY, Curley SA, et al. Overexpression of focal adhesion kinase (p125FAK) in human colorectal carcinoma liver metastases: independence from c-src or c-yes activation. Ann Surg Oncol 1997;4:264-268.
-
(1997)
Ann Surg Oncol
, vol.4
, pp. 264-268
-
-
Han, N.M.1
Fleming, R.Y.2
Curley, S.A.3
-
18
-
-
0037237066
-
Overexpression of focal adhesion kinase in primary colorectal carcinomas and colorectal liver metastases
-
Lark AL, Livasy CA, Calvo B, et al. Overexpression of focal adhesion kinase in primary colorectal carcinomas and colorectal liver metastases. Clin Cancer Res 2003;9:215-222.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 215-222
-
-
Lark, A.L.1
Livasy, C.A.2
Calvo, B.3
-
19
-
-
0029690892
-
The focal adhesion kinase as a marker of invasive potential in differentiated human thyroid cancer
-
Owens LV, Xu L, Dent GA, et al. The focal adhesion kinase as a marker of invasive potential in differentiated human thyroid cancer. Ann Surg Oncol 1996;3:100-105.
-
(1996)
Ann Surg Oncol
, vol.3
, pp. 100-105
-
-
Owens, L.V.1
Xu, L.2
Dent, G.A.3
-
20
-
-
0033570076
-
Overexpression of focal adhesion kinase, a protein tyrosine kinase, in ovarian carcinoma
-
Judson PL, He X, Cance WG, et al. Overexpression of focal adhesion kinase, a protein tyrosine kinase, in ovarian carcinoma. Cancer 1999;86:1551-1556.
-
(1999)
Cancer
, vol.86
, pp. 1551-1556
-
-
Judson, P.L.1
He, X.2
Cance, W.G.3
-
21
-
-
0031657454
-
Focal adhesion kinase and its potential involvement in tumor invasion and metastasis
-
Kornberg LJ. Focal adhesion kinase and its potential involvement in tumor invasion and metastasis. Head Neck 1998;20:745-752.
-
(1998)
Head Neck
, vol.20
, pp. 745-752
-
-
Kornberg, L.J.1
-
22
-
-
0041369959
-
FAK overexpression in correlated with tumour invasiveness and lymph node metastasis in oesophageal squamous cell carcinoma
-
Miyazaki T, Kato H, Nakajima M, et al. FAK overexpression in correlated with tumour invasiveness and lymph node metastasis in oesophageal squamous cell carcinoma. Br J Cancer 2003;89:140-145.
-
(2003)
Br J Cancer
, vol.89
, pp. 140-145
-
-
Miyazaki, T.1
Kato, H.2
Nakajima, M.3
-
23
-
-
0034730632
-
The focal adhesion kinase suppresses transformation-associated, anchorage-independent apoptosis in human breast cancer cells
-
Xu LH, Yang X, Bradham CA, et al. The focal adhesion kinase suppresses transformation-associated, anchorage-independent apoptosis in human breast cancer cells. J Biol Chem 2000;275:30597-30604.
-
(2000)
J Biol Chem
, vol.275
, pp. 30597-30604
-
-
Xu, L.H.1
Yang, X.2
Bradham, C.A.3
-
24
-
-
0032547796
-
Extracellular matrix survival signals transduced by focal adhesion kinase suppress p53-mediated apoptosis
-
Ilic D, Almeida EAC, Schlaepfer DD, et al. Extracellular matrix survival signals transduced by focal adhesion kinase suppress p53-mediated apoptosis. J Cell Biol 1998;143:547-560.
-
(1998)
J Cell Biol
, vol.143
, pp. 547-560
-
-
Ilic, D.1
Almeida, E.A.C.2
Schlaepfer, D.D.3
-
25
-
-
0036531921
-
Evalence and spectrum of p53 mutations associated with smoking in breast cancer
-
Conway K, Edmiston SN, Cui L, et al. evalence and spectrum of p53 mutations associated with smoking in breast cancer. Cancer Res 2002;62:1987-1995.
-
(2002)
Cancer Res
, vol.62
, pp. 1987-1995
-
-
Conway, K.1
Edmiston, S.N.2
Cui, L.3
-
26
-
-
0037899640
-
HER2 codon 655 polymorphism and risk of breast cancer in African Americans and whites
-
Millikan R, Eaton A, Worley K, et al. HER2 codon 655 polymorphism and risk of breast cancer in African Americans and whites. Breast Cancer Res Treat 2003;79:355-364.
-
(2003)
Breast Cancer Res Treat
, vol.79
, pp. 355-364
-
-
Millikan, R.1
Eaton, A.2
Worley, K.3
-
28
-
-
0033433958
-
Policy guidelines for the utilization of formalin-fixed, paraffin-embedded tissue sections: The UNC SPORE experience
-
Dressler LG, Geradts J, Burroughs M, et al. Policy guidelines for the utilization of formalin-fixed, paraffin-embedded tissue sections: the UNC SPORE experience. Breast Cancer Res Treat 1999;58:31-39.
-
(1999)
Breast Cancer Res Treat
, vol.58
, pp. 31-39
-
-
Dressler, L.G.1
Geradts, J.2
Burroughs, M.3
-
29
-
-
0028354305
-
c-erbB-2 expression and response to adjuvant therapy in women with node-positive early breast cancer
-
Muss HB, Thor AD, Berry DA. c-erbB-2 expression and response to adjuvant therapy in women with node-positive early breast cancer. N Engl J Med 1994;330:1260-1266.
-
(1994)
N Engl J Med
, vol.330
, pp. 1260-1266
-
-
Muss, H.B.1
Thor, A.D.2
Berry, D.A.3
-
30
-
-
0031903725
-
Cigarette smoking, N-acteyltransferases 1 and 2, and breast cancer risk
-
Millikan R, Pittman G, Newman B. Cigarette smoking, N-acteyltransferases 1 and 2, and breast cancer risk. Cancer Epidemiol Biomarkers Prev 1998;7:371-378.
-
(1998)
Cancer Epidemiol Biomarkers Prev
, vol.7
, pp. 371-378
-
-
Millikan, R.1
Pittman, G.2
Newman, B.3
-
32
-
-
0022406444
-
Amplification of a novel v-erbB-related gene in a human mammary carcinoma
-
King CR, Kraus MH, Aaronson SA. Amplification of a novel v-erbB-related gene in a human mammary carcinoma. Science 1985;229:974.
-
(1985)
Science
, vol.229
, pp. 974
-
-
King, C.R.1
Kraus, M.H.2
Aaronson, S.A.3
-
33
-
-
37049183697
-
Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
-
Slamon DJ, Clark GM, Wong SJ, et al. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 1987;235:177-182.
-
(1987)
Science
, vol.235
, pp. 177-182
-
-
Slamon, D.J.1
Clark, G.M.2
Wong, S.J.3
-
34
-
-
0024337144
-
Studies of the HER-2/neu protooncogene in human breast and ovarian cancer
-
Slamon DJ, Godolphin W, Jones LA. Studies of the HER-2/neu protooncogene in human breast and ovarian cancer. Science 1989;244:707-712.
-
(1989)
Science
, vol.244
, pp. 707-712
-
-
Slamon, D.J.1
Godolphin, W.2
Jones, L.A.3
-
35
-
-
0038393116
-
Heregulin and HER2 signaling selectively activates c-Src phosphorylation at tyrosine 215
-
Vadlamudi RK, Sahin AA, Adam L, et al. Heregulin and HER2 signaling selectively activates c-Src phosphorylation at tyrosine 215. FEBS Lett 2003;543:76-80.
-
(2003)
FEBS Lett
, vol.543
, pp. 76-80
-
-
Vadlamudi, R.K.1
Sahin, A.A.2
Adam, L.3
-
36
-
-
0029971297
-
A mechanism for regulation of the adhesion-associated protein tyrosine kinase pp125FAK
-
Richardson A, Parson TA. A mechanism for regulation of the adhesion-associated protein tyrosine kinase pp125FAK. Nature 1996;380:538-540.
-
(1996)
Nature
, vol.380
, pp. 538-540
-
-
Richardson, A.1
Parson, T.A.2
-
37
-
-
0041426730
-
Simultaneous inhibition of focal adhesion kinase and SRC enhances detachment and apoptosis in colon cancer cell lines
-
Golubovskaya VM, Gross S, Kaur AS, et al. Simultaneous inhibition of focal adhesion kinase and SRC enhances detachment and apoptosis in colon cancer cell lines. Mol Cancer Res 2003;10:755-764.
-
(2003)
Mol Cancer Res
, vol.10
, pp. 755-764
-
-
Golubovskaya, V.M.1
Gross, S.2
Kaur, A.S.3
-
38
-
-
0038005805
-
Focal adhesion kinase N-terminus in breast carcinoma cells induces rounding, detachment and apoptosis
-
Beviglia L, Golubovskaya V, Xu L, et al. Focal adhesion kinase N-terminus in breast carcinoma cells induces rounding, detachment and apoptosis. Biochem J 2003;373:201-210.
-
(2003)
Biochem J
, vol.373
, pp. 201-210
-
-
Beviglia, L.1
Golubovskaya, V.2
Xu, L.3
-
39
-
-
2942531163
-
Focal adhesion kinase suppresses apoptosis by binding to the death domain of receptor-interacting protein
-
Kurenova E, Xu LH, Yang X, et al. Focal adhesion kinase suppresses apoptosis by binding to the death domain of receptor-interacting protein. Mol Cell Biol 2004;24:4361-4371.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 4361-4371
-
-
Kurenova, E.1
Xu, L.H.2
Yang, X.3
|