Dietary selenite and azadeoxycytidine treatments affect dimethylhydrazine-induced aberrant crypt formation in rat colon and DNA methylation in HT-29 cells

Journal of Nutrition

Volumn 132, Issue 2, 2002, Pages 292-297

  Davis, Cindy D ^a   Uthus, Eric O ^a  

^a GRAND FORKS HUMAN NUTRITION RESEARCH CENTER   (United States)

Author keywords

Azadeoxycytidine; DNA methylation; DNA methyltransferase; HT 29; Selenium

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; DIMETHYLHYDRAZINE; DNA METHYLTRANSFERASE; GENOMIC DNA; SELENITE;

ANIMAL MODEL; ARTICLE; BODY WEIGHT; CELL CULTURE; COLON CANCER; CONTROLLED STUDY; DIETARY INTAKE; DNA METHYLATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; INTESTINE CRYPT; NONHUMAN; NUTRITIONAL STATUS; PROTEIN EXPRESSION; RAT;

ANIMALIA; PICHIA JADINII;

EID: 0036170179     PISSN: 00223166     EISSN: None     Source Type: Journal    
DOI: 10.1093/jn/132.2.292     Document Type: Article

References (42)

1. Lessons from hereditary colorectal cancer
2. Effect of selenium supplementation for cancer prevention in patients with carcinoma of the skin. A randomized controlled trial
3. Dietary selenium reduces the formation of aberrant crypts in rats administered 3,2′-dimethyl-4-aminobiphenyl
4. Cancer-protective properties of high-selenium broccoli
5. Effect of selenium on 1,2-dimethylhydrazine-induced intestinal cancer in rats
6. Evaluation of organoselenium compounds for potential chemopreventive properties in colon cancer
7. Hypermethylation of tumor suppressor genes in cancer
8. Alterations in DNA methylation: A fundamental aspect of neoplasia
9. Altered DNA methylation and genome instability: A new pathway to cancer?
10. The role of DNA methylation in mammalian epigenetics
11. Metylated DNA and MeCP2 recruit histone deacetylase to repress transcription
12. Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
13. Are dietary factors involved in DNA methylation associated with colon cancer?
14. Dietary selenium and arsenic affect DNA methylation in vitro in Caco-2 cells and in vivo in rat liver and colon
15. Abnormal regulation of DNA methyltransferase expression during colorectal carcinogenesis
16. Expression of an exogenous eukaryotic DNA methyltransferase gene induces transformation of NIH 3T3 cells
17. Expression of prokaryotic Hhal DNA methyltransferase in transforming and lethal to NIN 3T3 cells
18. Role of DNA 5-methylcytosine transferase in cell transformation by fos
19. Baculovirus-mediated expression and characterization of the full-length murine DNA methyltransferase
20. Suppression of intestinal neoplasia by DNA hypomethylation
21. DNA methylation as a target for drug design
22. Molecular, cellular and animal pharmacology of 5′-aza-2′-deoxycytidine
23. Toxicity of 5-aza-2′-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation
24. Role of estrogen receptor gene demethylation and DNA methyltransferase. DNA adduct formation in 5-aza-2′-deoxycytidine-induced cytotoxicity in human breast cancer cells
25. Report of the American Institute of Nutrition ad hoc committee on standards for nutritional studies
26. Selenium content of foods purchased in North Dakota
27. Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase
28. Isocratic high performance liquid chromatographic analysis of S-adenosylmethionine in animal tissues: The effect of exposure to nitrous oxide
29. Hyperhomocysteinemia induced by folic acid deficiency and methionine load-applications of a modified HPLC method
30. Nonrandom binding of the carcinogen N-hydroxy-2-acetylaminoflourene to repetitive sequences of rat liver DNA in vivo
31. Chronic alcohol consumption induces genomic but not p53-specific DNA hypomethylation in rat colon
32. DNA methylation as intermediate biomarker in colorectal cancer: Modulation by folic acid supplementation
33. Moderate folate deficiency does not cause global hypomethylation of hepatic and colonic DNA or c-myc specific hypomethylation of colonic DNA in rats
34. Inhibition of DNA cytosine methyltransferase by chemopreventive selenium compounds, determined by an improved assay for DNA cytosine methyltransferase and DNA cytosine methylation
35. A study of the mechanism of selenite-induced hypomethylated DNA and differentiation of Friend erytrhroleukemic cells
36. Selenite: A good inhibitor of rat-liver DNA methylase
37. Feedback regulation of DNA methyltransferase gene expression by methylation
38. Inhibition of AP-1 binding and transcription by gold and selenium involving conserved cysteine residues in Jun and Fos
39. AP-1 DNA-binding activity is inhibited by selenite and selenodiglutathione
40. Selenium deprivation decreases the activity of liver betaine homocysteine methyltransferase in rats
41. Ability of endogenous folate from soy protein isolate to maintain plasma homocysteine and hepatic DNA methylation during methyl group depletion in rats