Effects of caloric restriction on mitochondrial function and gene transcripts in rat muscle

American Journal of Physiology - Endocrinology and Metabolism

Volumn 283, Issue 1 46-1, 2002, Pages

  Sreekumar, R ^a   Unnikrishnan, J ^a   Fu, A ^a   Nygren, J ^a   Short, K R ^a   Schimke, J ^a   Barazzoni, R ^a   Nair, K Sreekumaran ^a  

^a MAYO CLINIC   (United States)

Author keywords

Microarrays and mitochondrial adenosine 5 triphosphate production; Rat muscle

Indexed keywords

ADENOSINE TRIPHOSPHATE; CITRATE SYNTHASE; CYTOCHROME C OXIDASE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; UNCOUPLING PROTEIN 2; UNCOUPLING PROTEIN 3;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALORIC RESTRICTION; CONTROLLED STUDY; DIET; DNA MICROARRAY; DNA SYNTHESIS; ENERGY METABOLISM; FEEDING; GENE EXPRESSION; GENETIC TRANSCRIPTION; LIFE EXPECTANCY; LONGEVITY; MUSCLE MITOCHONDRION; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RAT; RNA ISOLATION; SIGNAL TRANSDUCTION; SKELETAL MUSCLE;

EID: 0036288659     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.00387.2001     Document Type: Article

References (23)

1. Age effect on transcript levels and synthesis rate of muscle MHC and response to resistance exercise
2. Effects of aging on mitochondrial DNA copy number and cytochrome c oxidase gene expression in rat skeletal muscle, liver and heart
3. Changes in uncoupling protein-2 and -3 expression in aging rat skeletal muscle, liver, and heart
4. Mice overexpressing human uncoupling protein-3 in skeletal muscle are hyperphagic and lean
5. What is sarcopenia?
6. Lack of obesity and normal response to fasting and thyroid hormone in mice lacking uncoupling protein-3
7. An emerging hypothesis: Synergistic induction of aging by free radicals and maillard reactions
8. Gene expression profile of aging and its retardation by caloric restriction
9. Expression monitoring by hybridization to high-density oligonucleotide arrays
10. A high-density probe array sample preparation method using 10- to 100-fold fewer cells
11. Age-related changes in skeletal muscle function
12. Neuroendocrine involvement in aging - Evidence from studies of reproductive aging and caloric restriction
13. Extension of Drosophila lifespan by over-expression of human SOD1 in motor neurons
14. Gene expression and protein degradation
15. 3 increases mitochondrial ATP production in oxidative muscle despite increased expression of UCP 2 and UCP3
16. Oxidative stress, caloric restriction, and aging
17. Energy metabolism in uncoupling protein-3 gene knockout mice
18. The response to calorie restriction in mammals shows features also common to hibernation - A cross-adaptation hypothesis
19. Overexpression of human copper, zinc superoxide dismutase (SOD1) prevents postischemic injury
20. Interventions based on the possibility that oxidative stress contributes to sarcopenia
21. A sensitive method for measuring ATP-formation in rat muscle mitochondria
22. Aging and oxidative stress: Modulation by dietary restriction