Loss of transcriptional silencing causes sterility in old mother cells of S. cerevisiae

Cell

Volumn 84, Issue 4, 1996, Pages 633-642

  Smeal, Tod ^a   Claus, James ^a   Kennedy, Brian ^a   Cole, Francesca ^a   Guarente, Leonard ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CELL AGING; CELL SURVIVAL; GENE LOCUS; GENETIC TRANSCRIPTION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SILENCER GENE; SPOROGENESIS;

EID: 0030053650     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)81038-7     Document Type: Article

References (45)

1. Allsopp, R.C., Vaziri, H., Paterson, C., Goldstein, S., Younglai, E.V., Futcher, A.B., Greider, C.W., and Harley, C.B. (1992). Telomere length predicts replicative capacity of human fibroblasts. Proc. Natl. Acad. Sci. USA 89, 10114-10118.
2. Aparicio, O.M., Billington, B.L., and Gottschling, D.E. (1991). Modifiers of position effect are shared between telomeric and silent mating-type loci in S. Cerevisiae. Cell 66, 1279-1287.
3. Ballou, C.E. (1982). Yeast cell wall and cell surface. In The Molecular Biology of the Yeast Saccharomyces(Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press).
4. Bell, S.P., Kobayashi, R., and Stillman, B. (1993). Yeast origin recognition complex functions in transcription silencing and DNA replication. Science 262, 1844-1849.
5. Bertrand, H., Chan, B.S., and Griffiths, A.J. (1985). Insertion of a foreign DNA causes senescence in Neurospora intermedia. Cell 41, 877-884.
6. Bishop, D.K., Park, D., Xu, L., and Kleckner, N. (1992). DMC1: a meiosis-specific yeast homolog of E. coli recA required for recombination, synaptonemal complex formation, and cell cycle progression. Cell 69, 439-456.
7. Brand, A.H., Micklem, G., and Nasmyth, K. (1987). A yeast silencer contains sequences that can promote autonomous plasmid replication and transcriptional activation. Cell 51, 709-719.
8. Byers, B., and Goetsch, L. (1975). The behavior of spindles and spindle plaques in the cell cycle and conjugation of Saccharomyces cerevisiae. J. Bacteriol. 124, 511-523.
9. Cabib, E., and Bowers, B. (1971). Chitin and yeast budding: localization of chitin in yeast bud scars. J. Biol. Chem. 246, 152.
10. Cedar, H. (1988). DNA methylation and gene activity. Cell 53, 3-4.
11. Cockell, M., Palladino, F., Laroche, T., Kyrion, G., Liu, C., Lustig, A.J., and Gasser, S.M. (1995). The carboxy termini of Sir4 and Rap1 affect Sir3 localization: evidence for a multicomponent complex required for yeast telomeric silencing. J. Cell Biol. 129, 909-924.
12. D'Mello, N.P., and Jazwinski, S.M. (1991). Telomere length constancy during aging of Saccharomyces cerevisiae. J. Bacteriol. 173, 6709-6713.
13. Duke, R.C., Chervenak, R., and Cohen, J.J. (1983). Endogenous endonuclease-induced DNA fragmentation: an early event in cell-mediated cytolysis. Proc. Natl. Acad. Sci. USA 80, 6361-6365.
14. Eglimez, N.K., Chen, J.B., and Jazwinski, S.M. (1990). Preparation and partial characterization of old yeast cells. J. Gerontol. 45, B9-B17.
15. Finch, C.E., (1990). Longevity, Senescence, and the Genome (Chicago: University of Chicago Press).
16. Foss, M., McNally, F.J., Laurenson, P., and Rine, J. (1993). Origin recognition complex (ORC) in transcriptional silencing and DNA replication in S. cerevisiae. Science 262, 1838-1843.
17. Gilley, D., and Blackburn, E.H. (1994). Lack of telomere shortening during senescence in Paramecium. Proc. Natl. Acad. Sci. USA 91, 1955-1958.
18. Gottschling, D.E., Aparicio, O.M., Billington, B.L., and Zakian, V.A. (1990). Position effect at S. cerevisiae telomeres: reversible repression of pol II transcription. Cell 63, 751-762.
19. Han, M., and Grunstein, M. (1988). Nucleosome loss activates yeast downstream promoters in vivo. Cell 55, 1137-1145.
20. Harley, C.B., Futcher, A.B., and Greider, C.W. (1990). Telomeres shorten during aging of human fibroblasts. Nature 345, 458-460.
21. Hayflick, L. (1965). The limited in vitro lifetime of human diploid cell strains. Exp. Cell Res. 37, 614-636.
22. Holliday, R. (1987). The inheritance of epigenetic defects. Science 238, 163-170.
23. Ivy, J.M., Klar, A.J.S., and Hicks, J.B. (1986). Cloning and characterization of four SIR genes of Saccharomyces cerevisiae. Mol. Cell. Biol. 6, 688-702.
24. Jazwinski, S.M., Egilmez, N.K., and Chen, J.B. (1989). Replication control and cellular life span. Exp. Gerontol. 24, 423-436.
25. Kennedy, B.K., Austriaco, N.R., Jr., and Guarente, L. (1994). Daughter cells of Saccharomyces cerevisiae from old mothers display reduced life span. J. Cell Biol. 127, 1985-1993.
26. Kennedy, B.K., Austriaco, N.R., Jr., Zhang, J., and Guarente, L. (1995). Mutation in the silencing gene SIR4 can delay aging in S. cerevisiae. Cell 80, 485-496.
27. Kenyon, C., Chang, J., Gensch, E., Rudner, A., and Tabtiang, R. (1993). A C. elegans mutant that lives twice as long as wild type. Nature 366, 461-464.
28. Menees, T.M., Ross-Macdonald, P.B., and Roeder, G.S. (1992). MEI4, a meiosis-specific yeast gene required for chromosome synapsis. Mol. Cell. Biol. 12, 1340-1351.
29. Miller, A.M. (1984). The yeast MATa1 gene contains two introns. EMBO J. 3, 1061-1065.
30. 2 labelling. Biochem. J. 240, 431-435.
31. Mortimer, R.K., and Johnston, J.R. (1959). Life span of individual yeast cells. Nature 183, 1751-1752.
32. Müller, I. (1985). Parental age and the life span of zygotes of Saccharomyces cerevisiae. Antonie van Leeuwenhoek 51, 1-10.
33. Pillus, L., and Rine, J. (1989). Epigenetic inheritance of transcriptional states in S. cerevisiae. Cell 59, 637-647.
34. Pohley, H.J. (1987). A formal mortality analysis for populations of unicellular organisms. Mech. Aging Dev. 38, 231-243.
35. Reiser, K.M., Jennessy, S.M., and Last, J.A. (1987). Analysis of age-associated changes in collagen crosslinking in the skin and lung in monkeys and rats. Biochim. Biophys. Acta 926, 339-348.
36. Rine, J., and Herskowitz, I. (1987). Four genes responsible for a position effect on expression from HML and HMR in Saccharomyces cerevisiae. Genetics 116, 9-22.
37. Schekman, R., and Novick, P. (1982). The secretory process and yeast cell-surface assembly. The Molecular Biology of the Yeast Saccharomyces (Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press).
38. Schwartz, H.S., Dahir, G.A., and Butler, M.G. (1993). Telomere reduction in giant cell tumor of bone and with aging. Cancer Genet. Cytogenet. 71, 132-138.
39. Sussel, L., and Shore, D. (1991). Separation of transcriptional activation and silencing functions of the RAP1-encoded repressor/activator protein 1: isolation of viable mutants affecting both silencing and telomere length. Proc. Natl. Acad. Sci. USA 88, 7749-7753.
40. Vaziri, H., Schachter, F., Uchida, I., Wei, L., Zhu, X., Effros, R., Cohen, D., and Harley, C.B. (1993). Loss of telomeric DNA during aging of normal and trisomy 21 human lymphocytes. Am. J. Hum. Genet 52, 661-667.
41. Wareham, K.A., Lyon, M.F., Glenister, P.H., and Williams, E.D. (1987). Age-related reactivation of an X-linked gene. Nature 327, 725-727.
42. White, C.I., and Haber, J.E. (1990). Intermediates of recombination during mating type switching in Saccharomyces cerevisiae. EMBO J. 9, 663-673.
43. Woldringh, C.L., Flutter, K., and Huls, P.G. (1995). Production of senescent cells of Saccharomyces cerevisiae by centrifugal elutriation. Yeast 11, 361-369.
44. Wright, R.M., Horrum, M.A., and Cummings, D.J. (1982). Are mitochondrial structural genes selectively amplified during senescence in Podospora anserina? Cell 29, 505-515.
45. Wyllie, A.H. (1980). Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature 284, 555-556.