-
1
-
-
34347385993
-
Cell-selective mitochondrial targeting: Progress in mitochondrial medicine
-
Paliwal R, Rai S, Vaidya B, et al. Cell-selective mitochondrial targeting: progress in mitochondrial medicine. Curr Drug Deliv 2007; 4: 211-24.
-
(2007)
Curr Drug Deliv
, vol.4
, pp. 211-224
-
-
Paliwal, R.1
Rai, S.2
Vaidya, B.3
-
2
-
-
0036194529
-
Mitochondria as a pharmacological target
-
Szewczyk A, Wojtczak L. Mitochondria as a pharmacological target. Pharmacol Rev 2002; 54: 101-27.
-
(2002)
Pharmacol Rev
, vol.54
, pp. 101-127
-
-
Szewczyk, A.1
Wojtczak, L.2
-
3
-
-
34548240181
-
Delivery of drugs and macromolecules to mitochondria
-
Mukhopadhyay A, Weiner H. Delivery of drugs and macromolecules to mitochondria. Adv Drug Deliv Rev 2007; 59: 729-38.
-
(2007)
Adv Drug Deliv Rev
, vol.59
, pp. 729-738
-
-
Mukhopadhyay, A.1
Weiner, H.2
-
4
-
-
0343986284
-
Drug delivery to mitochondria: The key to mitochondrial medicine
-
Murphy MP, Smith RAJ. Drug delivery to mitochondria: the key to mitochondrial medicine. Adv Drug Deliv Rev 2000; 41: 235-50.
-
(2000)
Adv Drug Deliv Rev
, vol.41
, pp. 235-250
-
-
Murphy, M.P.1
Smith, R.A.J.2
-
5
-
-
51249109260
-
Mitochondrial drug delivery systems for macromolecule and their therapeutic application to mitochondrial diseases
-
Yamada Y, Harashima H. Mitochondrial drug delivery systems for macromolecule and their therapeutic application to mitochondrial diseases. Adv Drug Deliv Rev 2008; 60: 1439-62.
-
(2008)
Adv Drug Deliv Rev
, vol.60
, pp. 1439-1462
-
-
Yamada, Y.1
Harashima, H.2
-
6
-
-
33750216506
-
Mitochondrial myopathies
-
DiMauro S. Mitochondrial myopathies. Curr Opin Rheumatol 2006; 18: 636-41.
-
(2006)
Curr Opin Rheumatol
, vol.18
, pp. 636-641
-
-
DiMauro, S.1
-
7
-
-
33845353404
-
-
Martin LJ. Mitochondriopathy in Parkinson disease and amyotrophic lateral sclerosis. J Neuropathol Exp Neurol 2006; 65: 1103-10.
-
Martin LJ. Mitochondriopathy in Parkinson disease and amyotrophic lateral sclerosis. J Neuropathol Exp Neurol 2006; 65: 1103-10.
-
-
-
-
8
-
-
33846008430
-
A novel recurrent mitochondrial DNA mutation in ND3 gene is associated with isolated complex I deficiency causing Leigh syndrome and dystonia
-
Sarzi E, Brown MD, Lebon S, et al. A novel recurrent mitochondrial DNA mutation in ND3 gene is associated with isolated complex I deficiency causing Leigh syndrome and dystonia. Am J Med Genet A 2007; 143: 33-41.
-
(2007)
Am J Med Genet A
, vol.143
, pp. 33-41
-
-
Sarzi, E.1
Brown, M.D.2
Lebon, S.3
-
10
-
-
17744393686
-
Mitochondrial DNA mutations in human disease
-
Taylor RW, Turnbull DM. Mitochondrial DNA mutations in human disease. Nat Rev Genet 2005; 6: 389-402.
-
(2005)
Nat Rev Genet
, vol.6
, pp. 389-402
-
-
Taylor, R.W.1
Turnbull, D.M.2
-
11
-
-
0033374355
-
Peptide nucleic acid delivery to human mitochondria
-
Chinnery PF, Taylor RW, Diekert K, et al. Peptide nucleic acid delivery to human mitochondria. Gene Ther 1999; 6: 1919-28.
-
(1999)
Gene Ther
, vol.6
, pp. 1919-1928
-
-
Chinnery, P.F.1
Taylor, R.W.2
Diekert, K.3
-
12
-
-
0014690248
-
Apparent turnover of mitochondrial deoxyribonucleic acid and mitochondrial phospholipids in the tissues of the rat
-
Gross NJ, Getz GS, Rabinowitz M. Apparent turnover of mitochondrial deoxyribonucleic acid and mitochondrial phospholipids in the tissues of the rat. J Biol Chem 1969; 244: 1552-62.
-
(1969)
J Biol Chem
, vol.244
, pp. 1552-1562
-
-
Gross, N.J.1
Getz, G.S.2
Rabinowitz, M.3
-
13
-
-
0028310818
-
Mitochondrial DNA alterations and genetic diseases: A review
-
Lestienne P, Bataillé N. Mitochondrial DNA alterations and genetic diseases: a review. Biomed Pharmacother 1994; 48: 199-214.
-
(1994)
Biomed Pharmacother
, vol.48
, pp. 199-214
-
-
Lestienne, P.1
Bataillé, N.2
-
14
-
-
0024242545
-
Mitochondrial DNA mutation associated with Leber's hereditary optic neuropathy
-
Wallace DC, Singh G, Lott MT, et al. Mitochondrial DNA mutation associated with Leber's hereditary optic neuropathy. Science 1988; 242: 1427-30.
-
(1988)
Science
, vol.242
, pp. 1427-1430
-
-
Wallace, D.C.1
Singh, G.2
Lott, M.T.3
-
15
-
-
0035797150
-
Human mitochondrial DNA diseases
-
Pulkes T, Hanna MG. Human mitochondrial DNA diseases. Adv Drug Deliv Rev 2001; 49: 27-43.
-
(2001)
Adv Drug Deliv Rev
, vol.49
, pp. 27-43
-
-
Pulkes, T.1
Hanna, M.G.2
-
16
-
-
0027180961
-
-
Newman NJ. Leber's hereditary optic neuropathy. New genetic considerations. Arch Neurol 1993; 50: 540-8.
-
Newman NJ. Leber's hereditary optic neuropathy. New genetic considerations. Arch Neurol 1993; 50: 540-8.
-
-
-
-
18
-
-
0025666322
-
A mutation in the tRNA(Leu)(UUR) gene associated with the MELAS subgroup of mitochondrial encephalomyopathies
-
Goto Y, Nonaka I, Horai S. A mutation in the tRNA(Leu)(UUR) gene associated with the MELAS subgroup of mitochondrial encephalomyopathies. Nature 1990; 348: 651-3.
-
(1990)
Nature
, vol.348
, pp. 651-653
-
-
Goto, Y.1
Nonaka, I.2
Horai, S.3
-
19
-
-
0025368281
-
Myoclonic epilepsy and ragged-red fiber disease (MERRF) is associated with a mitochondrial DNA tRNA(Lys) mutation
-
Shoffner JM, Lott MT, Lezza AM, et al. Myoclonic epilepsy and ragged-red fiber disease (MERRF) is associated with a mitochondrial DNA tRNA(Lys) mutation. Cell 1990; 61; 931-7.
-
(1990)
Cell
, vol.61
, pp. 931-937
-
-
Shoffner, J.M.1
Lott, M.T.2
Lezza, A.M.3
-
21
-
-
0025191359
-
Widespread tissue distribution of mitochondrial DNA deletions in Kearns-Sayre syndrome
-
Shanske S, Moraes CT, Lombes A. et al. Widespread tissue distribution of mitochondrial DNA deletions in Kearns-Sayre syndrome. Neurology 1990; 40: 24-8.
-
(1990)
Neurology
, vol.40
, pp. 24-28
-
-
Shanske, S.1
Moraes, C.T.2
Lombes, A.3
-
22
-
-
0025322251
-
Marked decrease of mitochondrial DNA with multiple deletions in a patient with familial mitochondrial myopathy
-
Otsuka M, Niijima K, Mizuno Y, et al. Marked decrease of mitochondrial DNA with multiple deletions in a patient with familial mitochondrial myopathy. Biochem Biophys Res Commun 1990; 167: 680-5.
-
(1990)
Biochem Biophys Res Commun
, vol.167
, pp. 680-685
-
-
Otsuka, M.1
Niijima, K.2
Mizuno, Y.3
-
23
-
-
0035797132
-
Targeting large molecules to mitochondria
-
Muratovska A, Lightowlers RN, Taylor RW, Wilce JA, Murphy MP. Targeting large molecules to mitochondria. Adv Drug Deliv Rev 2001; 49: 189-98.
-
(2001)
Adv Drug Deliv Rev
, vol.49
, pp. 189-198
-
-
Muratovska, A.1
Lightowlers, R.N.2
Taylor, R.W.3
Wilce, J.A.4
Murphy, M.P.5
-
24
-
-
29444440132
-
Bio-Functional Inorganic Materials: An attractive branch of gene-based nano-medicine delivery for 21st century
-
Chowdhury EH, Akaike T. Bio-Functional Inorganic Materials: an attractive branch of gene-based nano-medicine delivery for 21st century. Curr Gene Ther 2005; 5: 669-76.
-
(2005)
Curr Gene Ther
, vol.5
, pp. 669-676
-
-
Chowdhury, E.H.1
Akaike, T.2
-
25
-
-
0002307753
-
Non-viral vectors in gene delivery
-
Schätzlein AG, Uchegbu IF. Non-viral vectors in gene delivery. Drug Deliv 2001; 1: 17-23.
-
(2001)
Drug Deliv
, vol.1
, pp. 17-23
-
-
Schätzlein, A.G.1
Uchegbu, I.F.2
-
26
-
-
0036560326
-
Intracellular barriers to non-viral gene transfer
-
Lechardeur D, Lukacs GL. Intracellular barriers to non-viral gene transfer. Curr Gene Ther 2002; 2: 1831-94
-
(2002)
Curr Gene Ther
, vol.2
, pp. 1831-1894
-
-
Lechardeur, D.1
Lukacs, G.L.2
-
27
-
-
0033766794
-
The intracellular fate of non-viral DNA carriers
-
Langner M. The intracellular fate of non-viral DNA carriers. Cell Mol Biol Lett 2000; 5: 295-313.
-
(2000)
Cell Mol Biol Lett
, vol.5
, pp. 295-313
-
-
Langner, M.1
-
28
-
-
22744457795
-
Biomembrane-active molecular switches as tools for intracellular drug delivery
-
Bulmus V. Biomembrane-active molecular switches as tools for intracellular drug delivery. Aust J Chem 2005; 58: 411-22.
-
(2005)
Aust J Chem
, vol.58
, pp. 411-422
-
-
Bulmus, V.1
-
29
-
-
34848857598
-
Targeted intracellular delivery of therapeutics: An overview
-
Rawat A, Vaidya B, Khatri K, et al. Targeted intracellular delivery of therapeutics: an overview. Pharmazie 2007; 62: 643-58.
-
(2007)
Pharmazie
, vol.62
, pp. 643-658
-
-
Rawat, A.1
Vaidya, B.2
Khatri, K.3
-
30
-
-
13844275977
-
Nuclear delivery of macromolecules: Barrier and carriers
-
Belting M, Sandgren S, Wittrup A. Nuclear delivery of macromolecules: barrier and carriers. Adv Drug Deliv Rev 2005; 57: 505-27.
-
(2005)
Adv Drug Deliv Rev
, vol.57
, pp. 505-527
-
-
Belting, M.1
Sandgren, S.2
Wittrup, A.3
-
31
-
-
0343067073
-
Lysosome membrane permeability: Implications for drug delivery
-
Lloyd JB. Lysosome membrane permeability: Implications for drug delivery. Adv Drug Deliv Rev 2000; 41: 189-200.
-
(2000)
Adv Drug Deliv Rev
, vol.41
, pp. 189-200
-
-
Lloyd, J.B.1
-
33
-
-
0028416237
-
Targeting of drugs to various blood cell types using (neo-) glycoproteins, antibiotics and other protein carriers
-
Molema G, Meijer DKF. Targeting of drugs to various blood cell types using (neo-) glycoproteins, antibiotics and other protein carriers. Adv Drug Deliv Rev 1994; 14: 25-50.
-
(1994)
Adv Drug Deliv Rev
, vol.14
, pp. 25-50
-
-
Molema, G.1
Meijer, D.K.F.2
-
34
-
-
33644593889
-
Uptake pathway and subsequent intracellular trafficking in nonviral gene delivery
-
Khalil IA, Kogure K, Akita H, Harashima H. Uptake pathway and subsequent intracellular trafficking in nonviral gene delivery. Pharmacol Rev 2006; 58: 32-45.
-
(2006)
Pharmacol Rev
, vol.58
, pp. 32-45
-
-
Khalil, I.A.1
Kogure, K.2
Akita, H.3
Harashima, H.4
-
35
-
-
59249105606
-
Polymer-based gene delivery: A current review on the uptake and intracellular trafficking of polyplexes
-
Midoux P, Breuzard G, Gomez JP, Pichon C. Polymer-based gene delivery: a current review on the uptake and intracellular trafficking of polyplexes. Curr Gene Ther 2008; 8: 335-52.
-
(2008)
Curr Gene Ther
, vol.8
, pp. 335-352
-
-
Midoux, P.1
Breuzard, G.2
Gomez, J.P.3
Pichon, C.4
-
37
-
-
0025911977
-
The preendosomal compartment comprises distinct coated and noncoated endocytic vesicle populations
-
Hansen SH, Sandvig K, van Deurs B. The preendosomal compartment comprises distinct coated and noncoated endocytic vesicle populations. J Cell Biol 1991; 113: 731-41.
-
(1991)
J Cell Biol
, vol.113
, pp. 731-741
-
-
Hansen, S.H.1
Sandvig, K.2
van Deurs, B.3
-
38
-
-
0035446006
-
Clathrin-mediated endocytosis: Membrane factors pull the trigger
-
Takei K, Haucke V. Clathrin-mediated endocytosis: membrane factors pull the trigger. Trends Cell Biol 2001; 11: 385-91.
-
(2001)
Trends Cell Biol
, vol.11
, pp. 385-391
-
-
Takei, K.1
Haucke, V.2
-
39
-
-
0036498556
-
Caveolae and caveolin in immune cells: Distribution and functions
-
Harris J, Werling D, Hope JC, Taylor G, Howard CJ. Caveolae and caveolin in immune cells: distribution and functions. Trends Immunol 2002; 23: 158-64.
-
(2002)
Trends Immunol
, vol.23
, pp. 158-164
-
-
Harris, J.1
Werling, D.2
Hope, J.C.3
Taylor, G.4
Howard, C.J.5
-
40
-
-
0037422066
-
Regulated portals of entry into the cell
-
Conner SD, Schmid SL. Regulated portals of entry into the cell. Nature (Lond) 2003; 422: 37-44.
-
(2003)
Nature (Lond)
, vol.422
, pp. 37-44
-
-
Conner, S.D.1
Schmid, S.L.2
-
42
-
-
0027361965
-
Molecules internalized by clathrin-independent endocytosis are delivered to endosomes containing transferrin receptors
-
Hansen SH, Sandvig K, van Deurs B. Molecules internalized by clathrin-independent endocytosis are delivered to endosomes containing transferrin receptors. J Cell Biol 1993; 123: 89-97.
-
(1993)
J Cell Biol
, vol.123
, pp. 89-97
-
-
Hansen, S.H.1
Sandvig, K.2
van Deurs, B.3
-
43
-
-
0030046514
-
Endocytosis of GPI-linked membrane folate receptor-alpha
-
Rijnboutt S, Jansen G, Posthuma G, et al. Endocytosis of GPI-linked membrane folate receptor-alpha. J Cell Biol 1996; 132: 35-47.
-
(1996)
J Cell Biol
, vol.132
, pp. 35-47
-
-
Rijnboutt, S.1
Jansen, G.2
Posthuma, G.3
-
44
-
-
10344221003
-
Cellular uptake of argininerich peptides: Roles for macropinocytosis and actin rearrangement
-
Nakase I, Niwa M, Takeuchi T, et al. Cellular uptake of argininerich peptides: roles for macropinocytosis and actin rearrangement. Mol Ther 2004; 10: 1011-22.
-
(2004)
Mol Ther
, vol.10
, pp. 1011-1022
-
-
Nakase, I.1
Niwa, M.2
Takeuchi, T.3
-
45
-
-
2342595835
-
Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis
-
Wadia JS, Stan RV, Dowdy SF. Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis. Nat Med 2004; 10: 310-15.
-
(2004)
Nat Med
, vol.10
, pp. 310-315
-
-
Wadia, J.S.1
Stan, R.V.2
Dowdy, S.F.3
-
46
-
-
11844268027
-
Cationic TAT peptide transduction domain enters cells by macropinocytosis
-
Kaplan IM, Wadia JS, Dowdy SF. Cationic TAT peptide transduction domain enters cells by macropinocytosis. J Control Rel 2005; 102: 247-53.
-
(2005)
J Control Rel
, vol.102
, pp. 247-253
-
-
Kaplan, I.M.1
Wadia, J.S.2
Dowdy, S.F.3
-
47
-
-
0029964866
-
Mechanism of oligonucleotide release from cationic liposomes
-
Zelphati O, Szoka FC, Jr. Mechanism of oligonucleotide release from cationic liposomes. Proc Natl Acad Sci USA 1996; 93: 11493-98.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 11493-11498
-
-
Zelphati, O.1
Szoka Jr., F.C.2
-
48
-
-
59249085987
-
Progress in cationic lipid-mediated gene transfection: A series of bioinspired lipids as an example
-
Montier T, Benvegnu T, Jaffrès P-A, Yaouanc J-J, Lehn P. Progress in cationic lipid-mediated gene transfection: a series of bioinspired lipids as an example. Curr Gene Ther 2008; 8: 296-312.
-
(2008)
Curr Gene Ther
, vol.8
, pp. 296-312
-
-
Montier, T.1
Benvegnu, T.2
Jaffrès, P.-A.3
Yaouanc, J.-J.4
Lehn, P.5
-
49
-
-
0032962975
-
Metabolic instability of plasmid DNA in the cytosol: A potential barrier to gene transfer
-
Lechardeur D, Sohn KJ, Haardt M, et al. Metabolic instability of plasmid DNA in the cytosol: a potential barrier to gene transfer. Gene Ther 1999; 6: 482-97.
-
(1999)
Gene Ther
, vol.6
, pp. 482-497
-
-
Lechardeur, D.1
Sohn, K.J.2
Haardt, M.3
-
50
-
-
13844298046
-
Intracellular delivery of large molecules and small particles by cell-penetrating proteins and peptides
-
Gupta B, Levchenko TS, Torchilin VP. Intracellular delivery of large molecules and small particles by cell-penetrating proteins and peptides. Adv Drug Del Rev 2005; 57: 637-51.
-
(2005)
Adv Drug Del Rev
, vol.57
, pp. 637-651
-
-
Gupta, B.1
Levchenko, T.S.2
Torchilin, V.P.3
-
51
-
-
0034694930
-
Receptor-mediated targeting of gene delivery vectors: Insights from molecular mechanisms for improved vehicle design
-
Varga CM, Wickham TJ, Lauffenburger DA. Receptor-mediated targeting of gene delivery vectors: insights from molecular mechanisms for improved vehicle design. Biotechnol Bioeng 2000; 70: 593-605.
-
(2000)
Biotechnol Bioeng
, vol.70
, pp. 593-605
-
-
Varga, C.M.1
Wickham, T.J.2
Lauffenburger, D.A.3
-
52
-
-
33746864903
-
Synthetic peptides as non-viral DNA vectors
-
Fabre JW, Collins L. Synthetic peptides as non-viral DNA vectors. Curr Gene Ther 2006; 6:459-80.
-
(2006)
Curr Gene Ther
, vol.6
, pp. 459-480
-
-
Fabre, J.W.1
Collins, L.2
-
53
-
-
33748126226
-
Recent approaches to intracellular delivery of drugs and DNA and organelle targeting
-
Torchilin VP. Recent approaches to intracellular delivery of drugs and DNA and organelle targeting. Annu Rev Biomed Eng 2006; 8: 343-75.
-
(2006)
Annu Rev Biomed Eng
, vol.8
, pp. 343-375
-
-
Torchilin, V.P.1
-
54
-
-
0034006169
-
TAT peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells
-
Lewin M, Carlesso N, Tung CH, et al. TAT peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells. Nat Biotechnol 2000; 18: 410-14.
-
(2000)
Nat Biotechnol
, vol.18
, pp. 410-414
-
-
Lewin, M.1
Carlesso, N.2
Tung, C.H.3
-
55
-
-
0034893552
-
Nanostructured materials designed for cell binding and transduction
-
Liu J, Zhang Q, Remsen EE, Wooley KL. Nanostructured materials designed for cell binding and transduction. Biomacromolecules 2001; 2: 362-8.
-
(2001)
Biomacromolecules
, vol.2
, pp. 362-368
-
-
Liu, J.1
Zhang, Q.2
Remsen, E.E.3
Wooley, K.L.4
-
56
-
-
0035480240
-
Normal T-cell response and in vivo magnetic resonance imaging of T cells loaded with HIV transactivator-peptide-derived superparamagnetic nanoparticles
-
Dodd CH, Hsu HC, Chu WJ, et al. Normal T-cell response and in vivo magnetic resonance imaging of T cells loaded with HIV transactivator-peptide-derived superparamagnetic nanoparticles. J Immunol Methods 2001; 256: 89-105.
-
(2001)
J Immunol Methods
, vol.256
, pp. 89-105
-
-
Dodd, C.H.1
Hsu, H.C.2
Chu, W.J.3
-
57
-
-
0035902477
-
TAT peptide on the surface of liposomes affords their efficient intracellular delivery even at low temperature and in the presence of metabolic inhibitors
-
Torchilin VP, Rammohan R, Weissig V, Levchenko TS. TAT peptide on the surface of liposomes affords their efficient intracellular delivery even at low temperature and in the presence of metabolic inhibitors, Proc Natl Acad Sci USA 2001; 98: 8786-91.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 8786-8791
-
-
Torchilin, V.P.1
Rammohan, R.2
Weissig, V.3
Levchenko, T.S.4
-
58
-
-
0242317898
-
TAT peptide-mediated intracellular delivery of liposomes
-
Levchenko TS, Rammohan R, Volodina N, Torchilin VP. TAT peptide-mediated intracellular delivery of liposomes, Methods Enzymol 2003; 372: 339-49.
-
(2003)
Methods Enzymol
, vol.372
, pp. 339-349
-
-
Levchenko, T.S.1
Rammohan, R.2
Volodina, N.3
Torchilin, V.P.4
-
59
-
-
33847682617
-
Enhancement of intracellular delivery of CdTe Quantum Dots (QDs) to living cells by Tat conjugation
-
Xue FL, Chen JY, Guo J, et al. Enhancement of intracellular delivery of CdTe Quantum Dots (QDs) to living cells by Tat conjugation. J Fluoresc 2007; 17: 149-54.
-
(2007)
J Fluoresc
, vol.17
, pp. 149-154
-
-
Xue, F.L.1
Chen, J.Y.2
Guo, J.3
-
60
-
-
0037452668
-
Cell transfection in vitro and in vivo with non-toxic TAT peptide-liposome-DNA complexes
-
Torchilin VP, Levchenko TS, Rammohan R, et al. Cell transfection in vitro and in vivo with non-toxic TAT peptide-liposome-DNA complexes. Proc Natl Acad Sci USA 2003; 100: 1972-7.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 1972-1977
-
-
Torchilin, V.P.1
Levchenko, T.S.2
Rammohan, R.3
-
61
-
-
34248229659
-
A protein derived from the fusion of TAT peptide and FNK, a Bcl-x(L) derivative, prevents cochlear hair cell death from aminoglycoside ototoxicity in vivo
-
Kashio A, Sakamoto T, Suzukawa K, et al. A protein derived from the fusion of TAT peptide and FNK, a Bcl-x(L) derivative, prevents cochlear hair cell death from aminoglycoside ototoxicity in vivo. J Neurosci Res 2007; 85: 1403-12.
-
(2007)
J Neurosci Res
, vol.85
, pp. 1403-1412
-
-
Kashio, A.1
Sakamoto, T.2
Suzukawa, K.3
-
63
-
-
0038730828
-
A novel TAT-mitochondrial signal sequence fusion protein is processed, stays in mitochondria, and crosses the placenta
-
Del Gaizo V, Payne RM. A novel TAT-mitochondrial signal sequence fusion protein is processed, stays in mitochondria, and crosses the placenta. Mol Ther 2003; 7: 720-30.
-
(2003)
Mol Ther
, vol.7
, pp. 720-730
-
-
Del Gaizo, V.1
Payne, R.M.2
-
64
-
-
0037168589
-
Protection against ischemic brain injury by protein therapeutics
-
Asoh S, Ohsawa I, Mori T, et al. Protection against ischemic brain injury by protein therapeutics. Proc Natl Acad Sci USA 2002; 99: 17107-12.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 17107-17112
-
-
Asoh, S.1
Ohsawa, I.2
Mori, T.3
-
65
-
-
36949083936
-
Coupling of phosphorylation to electron and hydrogen transfer by a chemi-osmotic type of mechanism
-
Mitchell P. Coupling of phosphorylation to electron and hydrogen transfer by a chemi-osmotic type of mechanism. Nature 1961; 191: 144-8.
-
(1961)
Nature
, vol.191
, pp. 144-148
-
-
Mitchell, P.1
-
66
-
-
0024422115
-
Slip and leak in mitochondrial oxidative phosphorylation
-
Murphy MP. Slip and leak in mitochondrial oxidative phosphorylation. Biochim Biophys Acta 1989; 977: 123-41.
-
(1989)
Biochim Biophys Acta
, vol.977
, pp. 123-141
-
-
Murphy, M.P.1
-
67
-
-
0002055897
-
Determination of the proton electrochemical gradient across biological membranes
-
Azzone GF, Pietrobon D, Zoratti M. Determination of the proton electrochemical gradient across biological membranes. Curr Top Bioenergy 1984; 13: 1-77.
-
(1984)
Curr Top Bioenergy
, vol.13
, pp. 1-77
-
-
Azzone, G.F.1
Pietrobon, D.2
Zoratti, M.3
-
68
-
-
0031106373
-
Labeling of mitochondrial proteins in living cells by the thiol probe thiobutyltriphenylphosphonium bromide
-
Burns RJ, Murphy MP. Labeling of mitochondrial proteins in living cells by the thiol probe thiobutyltriphenylphosphonium bromide. Arch Biochem Biophys 1997; 339: 33-9.
-
(1997)
Arch Biochem Biophys
, vol.339
, pp. 33-39
-
-
Burns, R.J.1
Murphy, M.P.2
-
69
-
-
0018337795
-
The measurement of membrane potential and deltapH in cells, organelles, and vesicles
-
Rottenberg H. The measurement of membrane potential and deltapH in cells, organelles, and vesicles. Methods Enzymol 1979; 55: 547-69.
-
(1979)
Methods Enzymol
, vol.55
, pp. 547-569
-
-
Rottenberg, H.1
-
70
-
-
0024148694
-
Mitochondrial membrane potential in living cells
-
Chen LB. Mitochondrial membrane potential in living cells. Annu Rev Cell Biol 1988; 4: 155-81.
-
(1988)
Annu Rev Cell Biol
, vol.4
, pp. 155-181
-
-
Chen, L.B.1
-
71
-
-
0030969942
-
Protein import into mitochondria
-
Neupert W. Protein import into mitochondria. Annu Rev Biochem 1997; 66: 863-17.
-
(1997)
Annu Rev Biochem
, vol.66
, pp. 863-917
-
-
Neupert, W.1
-
72
-
-
0029774146
-
The protein import system of mitochondria
-
Schatz GJ. The protein import system of mitochondria. J Biol Chem 1996; 271: 31763-66.
-
(1996)
J Biol Chem
, vol.271
, pp. 31763-31766
-
-
Schatz, G.J.1
-
74
-
-
0027963264
-
The protein import machinery of the mitochondrial inner membrane
-
Pfanner N, Craig EA, Meijer M. The protein import machinery of the mitochondrial inner membrane. Trends Biochem Sci 1994; 19: 368-72.
-
(1994)
Trends Biochem Sci
, vol.19
, pp. 368-372
-
-
Pfanner, N.1
Craig, E.A.2
Meijer, M.3
-
75
-
-
4544237885
-
Targeting of low-molecular weight drugs to mammalian mitochondria
-
Weissig V, Bodapati SV, D'Souza GGM, et al. Targeting of low-molecular weight drugs to mammalian mitochondria. Drug Des Rev 2004; 1: 15-28.
-
(2004)
Drug Des Rev
, vol.1
, pp. 15-28
-
-
Weissig, V.1
Bodapati, S.V.2
D'Souza, G.G.M.3
-
76
-
-
33847273537
-
Electrotransfer as a non viral method of gene delivery
-
Favard C, Dean DS, Rols M-P. Electrotransfer as a non viral method of gene delivery. Curr Gene Ther 2007; 7:67-77.
-
(2007)
Curr Gene Ther
, vol.7
, pp. 67-77
-
-
Favard, C.1
Dean, D.S.2
Rols, M.-P.3
-
77
-
-
0031054053
-
Introduction of plasmid DNA into isolated mitochondria by electroporation
-
Collombet JM, Wheeler VC, Vogel F, Coutelle C. Introduction of plasmid DNA into isolated mitochondria by electroporation. J Biol Chem 1997; 272: 5342-7.
-
(1997)
J Biol Chem
, vol.272
, pp. 5342-5347
-
-
Collombet, J.M.1
Wheeler, V.C.2
Vogel, F.3
Coutelle, C.4
-
78
-
-
0030725412
-
Modification of the mouse mitochondrial genome by insertion of an exogenous gene
-
Wheeler VC, Aitken M, Coutelle C. Modification of the mouse mitochondrial genome by insertion of an exogenous gene. Gene 1997; 198: 203-9.
-
(1997)
Gene
, vol.198
, pp. 203-209
-
-
Wheeler, V.C.1
Aitken, M.2
Coutelle, C.3
-
79
-
-
0025222081
-
Organelle transformation: Shoot first, ask questions later
-
Butow RA, Fox TD. Organelle transformation: shoot first, ask questions later. Trends Biochem Sci 1990; 15: 465-8.
-
(1990)
Trends Biochem Sci
, vol.15
, pp. 465-468
-
-
Butow, R.A.1
Fox, T.D.2
-
80
-
-
0035401236
-
Nonviral gene gherapy
-
Li S, Ma Z. Nonviral gene gherapy. Curr Gene Ther 2001; 1: 201-26.
-
(2001)
Curr Gene Ther
, vol.1
, pp. 201-226
-
-
Li, S.1
Ma, Z.2
-
81
-
-
0035797116
-
Cationic bolasomes with delocalized charge centers as mitochondria-specific DNA delivery systems
-
Weissig V, Torchilin VP. Cationic bolasomes with delocalized charge centers as mitochondria-specific DNA delivery systems. Adv Drug Deliv Rev 2001; 49: 127-49.
-
(2001)
Adv Drug Deliv Rev
, vol.49
, pp. 127-149
-
-
Weissig, V.1
Torchilin, V.P.2
-
82
-
-
0004207663
-
Selective targeting of an antioxidant to mitochondria
-
Smith RAJ, Porteous CM, Coulter CV, et al. Selective targeting of an antioxidant to mitochondria. Eur J Biochem 1999; 263: 709-16.
-
(1999)
Eur J Biochem
, vol.263
, pp. 709-716
-
-
Smith, R.A.J.1
Porteous, C.M.2
Coulter, C.V.3
-
83
-
-
0035895888
-
Selective targeting of a redox-active ubiquinone to mitochondria within cells
-
Kelso GF, Porteous CM, Coulter CV, et al. Selective targeting of a redox-active ubiquinone to mitochondria within cells. J Biol Chem 2001; 276: 4588-96.
-
(2001)
J Biol Chem
, vol.276
, pp. 4588-4596
-
-
Kelso, G.F.1
Porteous, C.M.2
Coulter, C.V.3
-
84
-
-
20444392739
-
Interactions of mitochondria-targeted and untargeted ubiquinones with the mitochondrial respiratory chain and reactive oxygen species. Implications for the use of exogenous ubiquinones as therapies and experimental tools
-
James AM, Cochemé HM, Smith RA, Murphy MP. Interactions of mitochondria-targeted and untargeted ubiquinones with the mitochondrial respiratory chain and reactive oxygen species. Implications for the use of exogenous ubiquinones as therapies and experimental tools. J Biol Chem 2005; 280: 21295-312.
-
(2005)
J Biol Chem
, vol.280
, pp. 21295-21312
-
-
James, A.M.1
Cochemé, H.M.2
Smith, R.A.3
Murphy, M.P.4
-
86
-
-
21244448078
-
Synthesis and characterization of a triphenylphosphonium-conjugated peroxidase mimetic: Insights into the interaction of ebselen with mitochondria
-
Filipovska A, Kelso GF, Brown SE, Beer SM, Smith RA, Murphy MP. Synthesis and characterization of a triphenylphosphonium-conjugated peroxidase mimetic: Insights into the interaction of ebselen with mitochondria. J Biol Chem 2005; 280: 24113-26.
-
(2005)
J Biol Chem
, vol.280
, pp. 24113-24126
-
-
Filipovska, A.1
Kelso, G.F.2
Brown, S.E.3
Beer, S.M.4
Smith, R.A.5
Murphy, M.P.6
-
87
-
-
33751103141
-
Accumulation of lipophilic dications by mitochondria and cells
-
Ross MF, Da Ros T, Blaikie FH, et al. Accumulation of lipophilic dications by mitochondria and cells. Biochem J 2006; 400: 199-208.
-
(2006)
Biochem J
, vol.400
, pp. 199-208
-
-
Ross, M.F.1
Da Ros, T.2
Blaikie, F.H.3
-
88
-
-
67349283471
-
An attempt to prevent senescence: A mitochondrial approach. Biochim et Biophys Acta (BBA)
-
Skulachev VP, Anisimov VN, Antonenko YN, et al. An attempt to prevent senescence: a mitochondrial approach. Biochim et Biophys Acta (BBA) - Bioenergetics 2009; 1787: 437-61.
-
(2009)
Bioenergetics
, vol.1787
, pp. 437-461
-
-
Skulachev, V.P.1
Anisimov, V.N.2
Antonenko, Y.N.3
-
89
-
-
0035339611
-
Targeting peptide nucleic acid (PNA) oligomers to mitochondria within cells by conjugation to lipophilic cations: Implications for mitochondrial DNA replication, expression and disease
-
Muratovska A, Lightowlers RN, Taylor RW, et al. Targeting peptide nucleic acid (PNA) oligomers to mitochondria within cells by conjugation to lipophilic cations: implications for mitochondrial DNA replication, expression and disease. Nucleic Acids Res 2001; 29: 1852-63.
-
(2001)
Nucleic Acids Res
, vol.29
, pp. 1852-1863
-
-
Muratovska, A.1
Lightowlers, R.N.2
Taylor, R.W.3
-
90
-
-
0030872907
-
Targeting bioactive compounds to mitochondria
-
Murphy MP. Targeting bioactive compounds to mitochondria. Trends Biotechnol 1997; 15: 326-30.
-
(1997)
Trends Biotechnol
, vol.15
, pp. 326-330
-
-
Murphy, M.P.1
-
91
-
-
0024317248
-
Tight folding of a passenger protein can interfere with the targeting function of a mitochondrial presequence
-
Verner K, Lemire BD. Tight folding of a passenger protein can interfere with the targeting function of a mitochondrial presequence. EMBO J 1989; 8: 1491-5.
-
(1989)
EMBO J
, vol.8
, pp. 1491-1495
-
-
Verner, K.1
Lemire, B.D.2
-
92
-
-
0038365420
-
Targeted delivery of DNA to the mitochondrial compartment via import sequence conjugated peptide nucleic acid
-
Flierl A, Jackson C, Cottrell B, et al. Targeted delivery of DNA to the mitochondrial compartment via import sequence conjugated peptide nucleic acid. Mol Ther 2003; 7: 550-7.
-
(2003)
Mol Ther
, vol.7
, pp. 550-557
-
-
Flierl, A.1
Jackson, C.2
Cottrell, B.3
-
93
-
-
0028804570
-
Transfection of mitochondria: Strategy towards a gene therapy of mitochondrial DNA diseases
-
Seibel P, Trappe J, Villani G, et al. Transfection of mitochondria: strategy towards a gene therapy of mitochondrial DNA diseases. Nucleic Acids Res 1995; 23: 10-17.
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 10-17
-
-
Seibel, P.1
Trappe, J.2
Villani, G.3
-
94
-
-
0024536726
-
DNA-protein conjugates can enter mitochondria via the protein import pathway
-
Vestweber D, Schatz G. DNA-protein conjugates can enter mitochondria via the protein import pathway. Nature 1989; 338: 170-2.
-
(1989)
Nature
, vol.338
, pp. 170-172
-
-
Vestweber, D.1
Schatz, G.2
-
95
-
-
13844317215
-
TAT-mediated protein transduction and targeted delivery of fusion proteins into mitochondria of breast cancer cells
-
Shokolenko IN, Alexeyev MF, LeDoux SP, Wilson GL. TAT-mediated protein transduction and targeted delivery of fusion proteins into mitochondria of breast cancer cells. DNA Repair (Amst) 2005; 4: 511-8.
-
(2005)
DNA Repair (Amst)
, vol.4
, pp. 511-518
-
-
Shokolenko, I.N.1
Alexeyev, M.F.2
LeDoux, S.P.3
Wilson, G.L.4
-
96
-
-
33749023859
-
Low molecular weight polyethylenimine-mitochondrial leader peptide conjugate for DNA delivery to mitochondria
-
Choi JS, Choi MJ, Ko KS, et al. Low molecular weight polyethylenimine-mitochondrial leader peptide conjugate for DNA delivery to mitochondria. Bull Korean Chem Soc 2006; 27: 1335-40.
-
(2006)
Bull Korean Chem Soc
, vol.27
, pp. 1335-1340
-
-
Choi, J.S.1
Choi, M.J.2
Ko, K.S.3
-
97
-
-
0029056088
-
Cellular and molecular barriers to gene transfer by a cationic lipid
-
Zabner J, Fasbender AJ, Moninger T, Poellinger KA, Welsh MJ. Cellular and molecular barriers to gene transfer by a cationic lipid. J Biol Chem 1995; 270:18997-9007.
-
(1995)
J Biol Chem
, vol.270
, pp. 18997-19007
-
-
Zabner, J.1
Fasbender, A.J.2
Moninger, T.3
Poellinger, K.A.4
Welsh, M.J.5
-
98
-
-
0025613174
-
Rapid nuclear accumulation of injected oligodeoxyribonucleotides
-
Chin DJ, Green GA, Zon G, Szoka FC, Jr, Straubinger RM. Rapid nuclear accumulation of injected oligodeoxyribonucleotides. N Biol 1990; 2:1091-100.
-
(1990)
N Biol
, vol.2
, pp. 1091-1100
-
-
Chin, D.J.1
Green, G.A.2
Zon, G.3
Szoka Jr, F.C.4
Straubinger, R.M.5
-
99
-
-
0029949266
-
Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection
-
Xu Y, Szoka FC. Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection. Biochemistry 1996; 35: 5616-23.
-
(1996)
Biochemistry
, vol.35
, pp. 5616-5623
-
-
Xu, Y.1
Szoka, F.C.2
-
100
-
-
0031916033
-
DQAsomes: A novel potential drug and gene delivery system made from Dequalinium
-
Weissig V, Lasch J, Erdos G, et al. DQAsomes: a novel potential drug and gene delivery system made from Dequalinium. Pharm Res 1998; 15: 334-7.
-
(1998)
Pharm Res
, vol.15
, pp. 334-337
-
-
Weissig, V.1
Lasch, J.2
Erdos, G.3
-
101
-
-
0034003553
-
Selective DNA release from DQAsome/DNA complexes at mitochondria-like membranes
-
Weissig V, Lizano C, Torchilin VP. Selective DNA release from DQAsome/DNA complexes at mitochondria-like membranes. Drug Deliv 2000; 7: 1-5.
-
(2000)
Drug Deliv
, vol.7
, pp. 1-5
-
-
Weissig, V.1
Lizano, C.2
Torchilin, V.P.3
-
102
-
-
0035839167
-
DQAsome/DNA complexes release DNA upon contact with isolated mouse liver mitochondria
-
Weissig V, D'Souza GG, Torchilin VP. DQAsome/DNA complexes release DNA upon contact with isolated mouse liver mitochondria. J Control Rel 2001; 75: 401-8.
-
(2001)
J Control Rel
, vol.75
, pp. 401-408
-
-
Weissig, V.1
D'Souza, G.G.2
Torchilin, V.P.3
-
103
-
-
0141763942
-
DQAsome-mediated delivery of plasmid DNA toward mitochondria in living cells
-
D'Souza GG, Rammohan R, Cheng SM, Torchilin VP, Weissig V. DQAsome-mediated delivery of plasmid DNA toward mitochondria in living cells. J Control Rel 2003; 92:189-97.
-
(2003)
J Control Rel
, vol.92
, pp. 189-197
-
-
D'Souza, G.G.1
Rammohan, R.2
Cheng, S.M.3
Torchilin, V.P.4
Weissig, V.5
-
104
-
-
0032586976
-
Dequalinium vesicles form stable complexes with plasmid DNA which are protected from DNase attack
-
Lasch J, Meye A, Taubert H, et al. Dequalinium vesicles form stable complexes with plasmid DNA which are protected from DNase attack. Biol Chem 1999; 380: 647-52.
-
(1999)
Biol Chem
, vol.380
, pp. 647-652
-
-
Lasch, J.1
Meye, A.2
Taubert, H.3
-
105
-
-
26444444018
-
Mitochondrial leader sequence-plasmid DNA conjugates delivered into mammalian cells by DQAsomes co-localize with mitochondria
-
D'Souza GG, Boddapati SV, Weissig V. Mitochondrial leader sequence-plasmid DNA conjugates delivered into mammalian cells by DQAsomes co-localize with mitochondria. Mitochondrion 2005; 5: 352-8.
-
(2005)
Mitochondrion
, vol.5
, pp. 352-358
-
-
D'Souza, G.G.1
Boddapati, S.V.2
Weissig, V.3
-
106
-
-
0023447252
-
Lipofection: A highly efficient, lipid-mediated DNA-transfection procedure
-
Felgner PL , Gadek TR , Holm M , et al. Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure. Proc Natl Acad Sci USA 1987; 84: 7413-7.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 7413-7417
-
-
Felgner, P.L.1
Gadek, T.R.2
Holm, M.3
-
107
-
-
34247855110
-
Nonviral gene delivery: What we know and what is next
-
Gao X, Kim KS, Liu D. Nonviral gene delivery: What we know and what is next. AAPS J 2007; 9: E92-104.
-
AAPS
, vol.J 2007
, Issue.9
-
-
Gao, X.1
Kim, K.S.2
Liu, D.3
-
108
-
-
12344302096
-
Targeted drug delivery to mammalian mitochondria in living cells
-
Weissig V. Targeted drug delivery to mammalian mitochondria in living cells. Expert Opin Drug Deliv 2005; 2: 89-102.
-
(2005)
Expert Opin Drug Deliv
, vol.2
, pp. 89-102
-
-
Weissig, V.1
-
109
-
-
69949176886
-
Cell-selective mitochondrial targeting: A new approach for cancer therapy
-
Vaidya B, Paliwal R, Rai S, et al. Cell-selective mitochondrial targeting: A new approach for cancer therapy. Cancer Ther 2009; 7(A): 141-8.
-
(2009)
Cancer Ther
, vol.7
, Issue.A
, pp. 141-148
-
-
Vaidya, B.1
Paliwal, R.2
Rai, S.3
|