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Volumn 9, Issue 6, 2009, Pages 475-486

Targeted nucleic acid delivery to mitochondria

Author keywords

Mitochondria targeting; Mitochondrial DNA; Nucleic acid delivery

Indexed keywords

CLATHRIN; DRUG CARRIER; FOLIC ACID; LIPOSOME; MITOCHONDRIAL DNA; MITOCHONDRIAL PROTEIN;

EID: 73449136874     PISSN: 15665232     EISSN: None     Source Type: Journal    
DOI: 10.2174/156652309790031102     Document Type: Review
Times cited : (10)

References (109)
  • 1
    • 34347385993 scopus 로고    scopus 로고
    • Cell-selective mitochondrial targeting: Progress in mitochondrial medicine
    • Paliwal R, Rai S, Vaidya B, et al. Cell-selective mitochondrial targeting: progress in mitochondrial medicine. Curr Drug Deliv 2007; 4: 211-24.
    • (2007) Curr Drug Deliv , vol.4 , pp. 211-224
    • Paliwal, R.1    Rai, S.2    Vaidya, B.3
  • 2
    • 0036194529 scopus 로고    scopus 로고
    • Mitochondria as a pharmacological target
    • Szewczyk A, Wojtczak L. Mitochondria as a pharmacological target. Pharmacol Rev 2002; 54: 101-27.
    • (2002) Pharmacol Rev , vol.54 , pp. 101-127
    • Szewczyk, A.1    Wojtczak, L.2
  • 3
    • 34548240181 scopus 로고    scopus 로고
    • Delivery of drugs and macromolecules to mitochondria
    • Mukhopadhyay A, Weiner H. Delivery of drugs and macromolecules to mitochondria. Adv Drug Deliv Rev 2007; 59: 729-38.
    • (2007) Adv Drug Deliv Rev , vol.59 , pp. 729-738
    • Mukhopadhyay, A.1    Weiner, H.2
  • 4
    • 0343986284 scopus 로고    scopus 로고
    • Drug delivery to mitochondria: The key to mitochondrial medicine
    • Murphy MP, Smith RAJ. Drug delivery to mitochondria: the key to mitochondrial medicine. Adv Drug Deliv Rev 2000; 41: 235-50.
    • (2000) Adv Drug Deliv Rev , vol.41 , pp. 235-250
    • Murphy, M.P.1    Smith, R.A.J.2
  • 5
    • 51249109260 scopus 로고    scopus 로고
    • Mitochondrial drug delivery systems for macromolecule and their therapeutic application to mitochondrial diseases
    • Yamada Y, Harashima H. Mitochondrial drug delivery systems for macromolecule and their therapeutic application to mitochondrial diseases. Adv Drug Deliv Rev 2008; 60: 1439-62.
    • (2008) Adv Drug Deliv Rev , vol.60 , pp. 1439-1462
    • Yamada, Y.1    Harashima, H.2
  • 6
    • 33750216506 scopus 로고    scopus 로고
    • Mitochondrial myopathies
    • DiMauro S. Mitochondrial myopathies. Curr Opin Rheumatol 2006; 18: 636-41.
    • (2006) Curr Opin Rheumatol , vol.18 , pp. 636-641
    • DiMauro, S.1
  • 7
    • 33845353404 scopus 로고    scopus 로고
    • Martin LJ. Mitochondriopathy in Parkinson disease and amyotrophic lateral sclerosis. J Neuropathol Exp Neurol 2006; 65: 1103-10.
    • Martin LJ. Mitochondriopathy in Parkinson disease and amyotrophic lateral sclerosis. J Neuropathol Exp Neurol 2006; 65: 1103-10.
  • 8
    • 33846008430 scopus 로고    scopus 로고
    • A novel recurrent mitochondrial DNA mutation in ND3 gene is associated with isolated complex I deficiency causing Leigh syndrome and dystonia
    • Sarzi E, Brown MD, Lebon S, et al. A novel recurrent mitochondrial DNA mutation in ND3 gene is associated with isolated complex I deficiency causing Leigh syndrome and dystonia. Am J Med Genet A 2007; 143: 33-41.
    • (2007) Am J Med Genet A , vol.143 , pp. 33-41
    • Sarzi, E.1    Brown, M.D.2    Lebon, S.3
  • 9
    • 0035797115 scopus 로고    scopus 로고
    • Gene therapy by mitochondrial transfer
    • Kagawa Y, Inoki Y, Endo H. Gene therapy by mitochondrial transfer. Adv Drug Deliv Rev 2001; 49: 107-19.
    • (2001) Adv Drug Deliv Rev , vol.49 , pp. 107-119
    • Kagawa, Y.1    Inoki, Y.2    Endo, H.3
  • 10
    • 17744393686 scopus 로고    scopus 로고
    • Mitochondrial DNA mutations in human disease
    • Taylor RW, Turnbull DM. Mitochondrial DNA mutations in human disease. Nat Rev Genet 2005; 6: 389-402.
    • (2005) Nat Rev Genet , vol.6 , pp. 389-402
    • Taylor, R.W.1    Turnbull, D.M.2
  • 11
    • 0033374355 scopus 로고    scopus 로고
    • Peptide nucleic acid delivery to human mitochondria
    • Chinnery PF, Taylor RW, Diekert K, et al. Peptide nucleic acid delivery to human mitochondria. Gene Ther 1999; 6: 1919-28.
    • (1999) Gene Ther , vol.6 , pp. 1919-1928
    • Chinnery, P.F.1    Taylor, R.W.2    Diekert, K.3
  • 12
    • 0014690248 scopus 로고
    • Apparent turnover of mitochondrial deoxyribonucleic acid and mitochondrial phospholipids in the tissues of the rat
    • Gross NJ, Getz GS, Rabinowitz M. Apparent turnover of mitochondrial deoxyribonucleic acid and mitochondrial phospholipids in the tissues of the rat. J Biol Chem 1969; 244: 1552-62.
    • (1969) J Biol Chem , vol.244 , pp. 1552-1562
    • Gross, N.J.1    Getz, G.S.2    Rabinowitz, M.3
  • 13
    • 0028310818 scopus 로고
    • Mitochondrial DNA alterations and genetic diseases: A review
    • Lestienne P, Bataillé N. Mitochondrial DNA alterations and genetic diseases: a review. Biomed Pharmacother 1994; 48: 199-214.
    • (1994) Biomed Pharmacother , vol.48 , pp. 199-214
    • Lestienne, P.1    Bataillé, N.2
  • 14
    • 0024242545 scopus 로고
    • Mitochondrial DNA mutation associated with Leber's hereditary optic neuropathy
    • Wallace DC, Singh G, Lott MT, et al. Mitochondrial DNA mutation associated with Leber's hereditary optic neuropathy. Science 1988; 242: 1427-30.
    • (1988) Science , vol.242 , pp. 1427-1430
    • Wallace, D.C.1    Singh, G.2    Lott, M.T.3
  • 15
    • 0035797150 scopus 로고    scopus 로고
    • Human mitochondrial DNA diseases
    • Pulkes T, Hanna MG. Human mitochondrial DNA diseases. Adv Drug Deliv Rev 2001; 49: 27-43.
    • (2001) Adv Drug Deliv Rev , vol.49 , pp. 27-43
    • Pulkes, T.1    Hanna, M.G.2
  • 16
    • 0027180961 scopus 로고    scopus 로고
    • Newman NJ. Leber's hereditary optic neuropathy. New genetic considerations. Arch Neurol 1993; 50: 540-8.
    • Newman NJ. Leber's hereditary optic neuropathy. New genetic considerations. Arch Neurol 1993; 50: 540-8.
  • 17
    • 0025267548 scopus 로고
    • A new mitochondrial disease associated with mitochondrial DNA heteroplasmy
    • Holt IJ, Harding AE, Petty RK, Morgan-Hughes JA. A new mitochondrial disease associated with mitochondrial DNA heteroplasmy. Am J Hum Genet 1990; 46: 428-33.
    • (1990) Am J Hum Genet , vol.46 , pp. 428-433
    • Holt, I.J.1    Harding, A.E.2    Petty, R.K.3    Morgan-Hughes, J.A.4
  • 18
    • 0025666322 scopus 로고
    • A mutation in the tRNA(Leu)(UUR) gene associated with the MELAS subgroup of mitochondrial encephalomyopathies
    • Goto Y, Nonaka I, Horai S. A mutation in the tRNA(Leu)(UUR) gene associated with the MELAS subgroup of mitochondrial encephalomyopathies. Nature 1990; 348: 651-3.
    • (1990) Nature , vol.348 , pp. 651-653
    • Goto, Y.1    Nonaka, I.2    Horai, S.3
  • 19
    • 0025368281 scopus 로고
    • Myoclonic epilepsy and ragged-red fiber disease (MERRF) is associated with a mitochondrial DNA tRNA(Lys) mutation
    • Shoffner JM, Lott MT, Lezza AM, et al. Myoclonic epilepsy and ragged-red fiber disease (MERRF) is associated with a mitochondrial DNA tRNA(Lys) mutation. Cell 1990; 61; 931-7.
    • (1990) Cell , vol.61 , pp. 931-937
    • Shoffner, J.M.1    Lott, M.T.2    Lezza, A.M.3
  • 21
    • 0025191359 scopus 로고
    • Widespread tissue distribution of mitochondrial DNA deletions in Kearns-Sayre syndrome
    • Shanske S, Moraes CT, Lombes A. et al. Widespread tissue distribution of mitochondrial DNA deletions in Kearns-Sayre syndrome. Neurology 1990; 40: 24-8.
    • (1990) Neurology , vol.40 , pp. 24-28
    • Shanske, S.1    Moraes, C.T.2    Lombes, A.3
  • 22
    • 0025322251 scopus 로고
    • Marked decrease of mitochondrial DNA with multiple deletions in a patient with familial mitochondrial myopathy
    • Otsuka M, Niijima K, Mizuno Y, et al. Marked decrease of mitochondrial DNA with multiple deletions in a patient with familial mitochondrial myopathy. Biochem Biophys Res Commun 1990; 167: 680-5.
    • (1990) Biochem Biophys Res Commun , vol.167 , pp. 680-685
    • Otsuka, M.1    Niijima, K.2    Mizuno, Y.3
  • 24
    • 29444440132 scopus 로고    scopus 로고
    • Bio-Functional Inorganic Materials: An attractive branch of gene-based nano-medicine delivery for 21st century
    • Chowdhury EH, Akaike T. Bio-Functional Inorganic Materials: an attractive branch of gene-based nano-medicine delivery for 21st century. Curr Gene Ther 2005; 5: 669-76.
    • (2005) Curr Gene Ther , vol.5 , pp. 669-676
    • Chowdhury, E.H.1    Akaike, T.2
  • 25
    • 0002307753 scopus 로고    scopus 로고
    • Non-viral vectors in gene delivery
    • Schätzlein AG, Uchegbu IF. Non-viral vectors in gene delivery. Drug Deliv 2001; 1: 17-23.
    • (2001) Drug Deliv , vol.1 , pp. 17-23
    • Schätzlein, A.G.1    Uchegbu, I.F.2
  • 26
    • 0036560326 scopus 로고    scopus 로고
    • Intracellular barriers to non-viral gene transfer
    • Lechardeur D, Lukacs GL. Intracellular barriers to non-viral gene transfer. Curr Gene Ther 2002; 2: 1831-94
    • (2002) Curr Gene Ther , vol.2 , pp. 1831-1894
    • Lechardeur, D.1    Lukacs, G.L.2
  • 27
    • 0033766794 scopus 로고    scopus 로고
    • The intracellular fate of non-viral DNA carriers
    • Langner M. The intracellular fate of non-viral DNA carriers. Cell Mol Biol Lett 2000; 5: 295-313.
    • (2000) Cell Mol Biol Lett , vol.5 , pp. 295-313
    • Langner, M.1
  • 28
    • 22744457795 scopus 로고    scopus 로고
    • Biomembrane-active molecular switches as tools for intracellular drug delivery
    • Bulmus V. Biomembrane-active molecular switches as tools for intracellular drug delivery. Aust J Chem 2005; 58: 411-22.
    • (2005) Aust J Chem , vol.58 , pp. 411-422
    • Bulmus, V.1
  • 29
    • 34848857598 scopus 로고    scopus 로고
    • Targeted intracellular delivery of therapeutics: An overview
    • Rawat A, Vaidya B, Khatri K, et al. Targeted intracellular delivery of therapeutics: an overview. Pharmazie 2007; 62: 643-58.
    • (2007) Pharmazie , vol.62 , pp. 643-658
    • Rawat, A.1    Vaidya, B.2    Khatri, K.3
  • 30
    • 13844275977 scopus 로고    scopus 로고
    • Nuclear delivery of macromolecules: Barrier and carriers
    • Belting M, Sandgren S, Wittrup A. Nuclear delivery of macromolecules: barrier and carriers. Adv Drug Deliv Rev 2005; 57: 505-27.
    • (2005) Adv Drug Deliv Rev , vol.57 , pp. 505-527
    • Belting, M.1    Sandgren, S.2    Wittrup, A.3
  • 31
    • 0343067073 scopus 로고    scopus 로고
    • Lysosome membrane permeability: Implications for drug delivery
    • Lloyd JB. Lysosome membrane permeability: Implications for drug delivery. Adv Drug Deliv Rev 2000; 41: 189-200.
    • (2000) Adv Drug Deliv Rev , vol.41 , pp. 189-200
    • Lloyd, J.B.1
  • 33
    • 0028416237 scopus 로고
    • Targeting of drugs to various blood cell types using (neo-) glycoproteins, antibiotics and other protein carriers
    • Molema G, Meijer DKF. Targeting of drugs to various blood cell types using (neo-) glycoproteins, antibiotics and other protein carriers. Adv Drug Deliv Rev 1994; 14: 25-50.
    • (1994) Adv Drug Deliv Rev , vol.14 , pp. 25-50
    • Molema, G.1    Meijer, D.K.F.2
  • 34
    • 33644593889 scopus 로고    scopus 로고
    • Uptake pathway and subsequent intracellular trafficking in nonviral gene delivery
    • Khalil IA, Kogure K, Akita H, Harashima H. Uptake pathway and subsequent intracellular trafficking in nonviral gene delivery. Pharmacol Rev 2006; 58: 32-45.
    • (2006) Pharmacol Rev , vol.58 , pp. 32-45
    • Khalil, I.A.1    Kogure, K.2    Akita, H.3    Harashima, H.4
  • 35
    • 59249105606 scopus 로고    scopus 로고
    • Polymer-based gene delivery: A current review on the uptake and intracellular trafficking of polyplexes
    • Midoux P, Breuzard G, Gomez JP, Pichon C. Polymer-based gene delivery: a current review on the uptake and intracellular trafficking of polyplexes. Curr Gene Ther 2008; 8: 335-52.
    • (2008) Curr Gene Ther , vol.8 , pp. 335-352
    • Midoux, P.1    Breuzard, G.2    Gomez, J.P.3    Pichon, C.4
  • 37
    • 0025911977 scopus 로고
    • The preendosomal compartment comprises distinct coated and noncoated endocytic vesicle populations
    • Hansen SH, Sandvig K, van Deurs B. The preendosomal compartment comprises distinct coated and noncoated endocytic vesicle populations. J Cell Biol 1991; 113: 731-41.
    • (1991) J Cell Biol , vol.113 , pp. 731-741
    • Hansen, S.H.1    Sandvig, K.2    van Deurs, B.3
  • 38
    • 0035446006 scopus 로고    scopus 로고
    • Clathrin-mediated endocytosis: Membrane factors pull the trigger
    • Takei K, Haucke V. Clathrin-mediated endocytosis: membrane factors pull the trigger. Trends Cell Biol 2001; 11: 385-91.
    • (2001) Trends Cell Biol , vol.11 , pp. 385-391
    • Takei, K.1    Haucke, V.2
  • 40
    • 0037422066 scopus 로고    scopus 로고
    • Regulated portals of entry into the cell
    • Conner SD, Schmid SL. Regulated portals of entry into the cell. Nature (Lond) 2003; 422: 37-44.
    • (2003) Nature (Lond) , vol.422 , pp. 37-44
    • Conner, S.D.1    Schmid, S.L.2
  • 41
  • 42
    • 0027361965 scopus 로고
    • Molecules internalized by clathrin-independent endocytosis are delivered to endosomes containing transferrin receptors
    • Hansen SH, Sandvig K, van Deurs B. Molecules internalized by clathrin-independent endocytosis are delivered to endosomes containing transferrin receptors. J Cell Biol 1993; 123: 89-97.
    • (1993) J Cell Biol , vol.123 , pp. 89-97
    • Hansen, S.H.1    Sandvig, K.2    van Deurs, B.3
  • 43
    • 0030046514 scopus 로고    scopus 로고
    • Endocytosis of GPI-linked membrane folate receptor-alpha
    • Rijnboutt S, Jansen G, Posthuma G, et al. Endocytosis of GPI-linked membrane folate receptor-alpha. J Cell Biol 1996; 132: 35-47.
    • (1996) J Cell Biol , vol.132 , pp. 35-47
    • Rijnboutt, S.1    Jansen, G.2    Posthuma, G.3
  • 44
    • 10344221003 scopus 로고    scopus 로고
    • Cellular uptake of argininerich peptides: Roles for macropinocytosis and actin rearrangement
    • Nakase I, Niwa M, Takeuchi T, et al. Cellular uptake of argininerich peptides: roles for macropinocytosis and actin rearrangement. Mol Ther 2004; 10: 1011-22.
    • (2004) Mol Ther , vol.10 , pp. 1011-1022
    • Nakase, I.1    Niwa, M.2    Takeuchi, T.3
  • 45
    • 2342595835 scopus 로고    scopus 로고
    • Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis
    • Wadia JS, Stan RV, Dowdy SF. Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis. Nat Med 2004; 10: 310-15.
    • (2004) Nat Med , vol.10 , pp. 310-315
    • Wadia, J.S.1    Stan, R.V.2    Dowdy, S.F.3
  • 46
    • 11844268027 scopus 로고    scopus 로고
    • Cationic TAT peptide transduction domain enters cells by macropinocytosis
    • Kaplan IM, Wadia JS, Dowdy SF. Cationic TAT peptide transduction domain enters cells by macropinocytosis. J Control Rel 2005; 102: 247-53.
    • (2005) J Control Rel , vol.102 , pp. 247-253
    • Kaplan, I.M.1    Wadia, J.S.2    Dowdy, S.F.3
  • 47
    • 0029964866 scopus 로고    scopus 로고
    • Mechanism of oligonucleotide release from cationic liposomes
    • Zelphati O, Szoka FC, Jr. Mechanism of oligonucleotide release from cationic liposomes. Proc Natl Acad Sci USA 1996; 93: 11493-98.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 11493-11498
    • Zelphati, O.1    Szoka Jr., F.C.2
  • 48
    • 59249085987 scopus 로고    scopus 로고
    • Progress in cationic lipid-mediated gene transfection: A series of bioinspired lipids as an example
    • Montier T, Benvegnu T, Jaffrès P-A, Yaouanc J-J, Lehn P. Progress in cationic lipid-mediated gene transfection: a series of bioinspired lipids as an example. Curr Gene Ther 2008; 8: 296-312.
    • (2008) Curr Gene Ther , vol.8 , pp. 296-312
    • Montier, T.1    Benvegnu, T.2    Jaffrès, P.-A.3    Yaouanc, J.-J.4    Lehn, P.5
  • 49
    • 0032962975 scopus 로고    scopus 로고
    • Metabolic instability of plasmid DNA in the cytosol: A potential barrier to gene transfer
    • Lechardeur D, Sohn KJ, Haardt M, et al. Metabolic instability of plasmid DNA in the cytosol: a potential barrier to gene transfer. Gene Ther 1999; 6: 482-97.
    • (1999) Gene Ther , vol.6 , pp. 482-497
    • Lechardeur, D.1    Sohn, K.J.2    Haardt, M.3
  • 50
    • 13844298046 scopus 로고    scopus 로고
    • Intracellular delivery of large molecules and small particles by cell-penetrating proteins and peptides
    • Gupta B, Levchenko TS, Torchilin VP. Intracellular delivery of large molecules and small particles by cell-penetrating proteins and peptides. Adv Drug Del Rev 2005; 57: 637-51.
    • (2005) Adv Drug Del Rev , vol.57 , pp. 637-651
    • Gupta, B.1    Levchenko, T.S.2    Torchilin, V.P.3
  • 51
    • 0034694930 scopus 로고    scopus 로고
    • Receptor-mediated targeting of gene delivery vectors: Insights from molecular mechanisms for improved vehicle design
    • Varga CM, Wickham TJ, Lauffenburger DA. Receptor-mediated targeting of gene delivery vectors: insights from molecular mechanisms for improved vehicle design. Biotechnol Bioeng 2000; 70: 593-605.
    • (2000) Biotechnol Bioeng , vol.70 , pp. 593-605
    • Varga, C.M.1    Wickham, T.J.2    Lauffenburger, D.A.3
  • 52
    • 33746864903 scopus 로고    scopus 로고
    • Synthetic peptides as non-viral DNA vectors
    • Fabre JW, Collins L. Synthetic peptides as non-viral DNA vectors. Curr Gene Ther 2006; 6:459-80.
    • (2006) Curr Gene Ther , vol.6 , pp. 459-480
    • Fabre, J.W.1    Collins, L.2
  • 53
    • 33748126226 scopus 로고    scopus 로고
    • Recent approaches to intracellular delivery of drugs and DNA and organelle targeting
    • Torchilin VP. Recent approaches to intracellular delivery of drugs and DNA and organelle targeting. Annu Rev Biomed Eng 2006; 8: 343-75.
    • (2006) Annu Rev Biomed Eng , vol.8 , pp. 343-375
    • Torchilin, V.P.1
  • 54
    • 0034006169 scopus 로고    scopus 로고
    • TAT peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells
    • Lewin M, Carlesso N, Tung CH, et al. TAT peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells. Nat Biotechnol 2000; 18: 410-14.
    • (2000) Nat Biotechnol , vol.18 , pp. 410-414
    • Lewin, M.1    Carlesso, N.2    Tung, C.H.3
  • 55
    • 0034893552 scopus 로고    scopus 로고
    • Nanostructured materials designed for cell binding and transduction
    • Liu J, Zhang Q, Remsen EE, Wooley KL. Nanostructured materials designed for cell binding and transduction. Biomacromolecules 2001; 2: 362-8.
    • (2001) Biomacromolecules , vol.2 , pp. 362-368
    • Liu, J.1    Zhang, Q.2    Remsen, E.E.3    Wooley, K.L.4
  • 56
    • 0035480240 scopus 로고    scopus 로고
    • Normal T-cell response and in vivo magnetic resonance imaging of T cells loaded with HIV transactivator-peptide-derived superparamagnetic nanoparticles
    • Dodd CH, Hsu HC, Chu WJ, et al. Normal T-cell response and in vivo magnetic resonance imaging of T cells loaded with HIV transactivator-peptide-derived superparamagnetic nanoparticles. J Immunol Methods 2001; 256: 89-105.
    • (2001) J Immunol Methods , vol.256 , pp. 89-105
    • Dodd, C.H.1    Hsu, H.C.2    Chu, W.J.3
  • 57
    • 0035902477 scopus 로고    scopus 로고
    • TAT peptide on the surface of liposomes affords their efficient intracellular delivery even at low temperature and in the presence of metabolic inhibitors
    • Torchilin VP, Rammohan R, Weissig V, Levchenko TS. TAT peptide on the surface of liposomes affords their efficient intracellular delivery even at low temperature and in the presence of metabolic inhibitors, Proc Natl Acad Sci USA 2001; 98: 8786-91.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 8786-8791
    • Torchilin, V.P.1    Rammohan, R.2    Weissig, V.3    Levchenko, T.S.4
  • 59
    • 33847682617 scopus 로고    scopus 로고
    • Enhancement of intracellular delivery of CdTe Quantum Dots (QDs) to living cells by Tat conjugation
    • Xue FL, Chen JY, Guo J, et al. Enhancement of intracellular delivery of CdTe Quantum Dots (QDs) to living cells by Tat conjugation. J Fluoresc 2007; 17: 149-54.
    • (2007) J Fluoresc , vol.17 , pp. 149-154
    • Xue, F.L.1    Chen, J.Y.2    Guo, J.3
  • 60
    • 0037452668 scopus 로고    scopus 로고
    • Cell transfection in vitro and in vivo with non-toxic TAT peptide-liposome-DNA complexes
    • Torchilin VP, Levchenko TS, Rammohan R, et al. Cell transfection in vitro and in vivo with non-toxic TAT peptide-liposome-DNA complexes. Proc Natl Acad Sci USA 2003; 100: 1972-7.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 1972-1977
    • Torchilin, V.P.1    Levchenko, T.S.2    Rammohan, R.3
  • 61
    • 34248229659 scopus 로고    scopus 로고
    • A protein derived from the fusion of TAT peptide and FNK, a Bcl-x(L) derivative, prevents cochlear hair cell death from aminoglycoside ototoxicity in vivo
    • Kashio A, Sakamoto T, Suzukawa K, et al. A protein derived from the fusion of TAT peptide and FNK, a Bcl-x(L) derivative, prevents cochlear hair cell death from aminoglycoside ototoxicity in vivo. J Neurosci Res 2007; 85: 1403-12.
    • (2007) J Neurosci Res , vol.85 , pp. 1403-1412
    • Kashio, A.1    Sakamoto, T.2    Suzukawa, K.3
  • 63
    • 0038730828 scopus 로고    scopus 로고
    • A novel TAT-mitochondrial signal sequence fusion protein is processed, stays in mitochondria, and crosses the placenta
    • Del Gaizo V, Payne RM. A novel TAT-mitochondrial signal sequence fusion protein is processed, stays in mitochondria, and crosses the placenta. Mol Ther 2003; 7: 720-30.
    • (2003) Mol Ther , vol.7 , pp. 720-730
    • Del Gaizo, V.1    Payne, R.M.2
  • 64
    • 0037168589 scopus 로고    scopus 로고
    • Protection against ischemic brain injury by protein therapeutics
    • Asoh S, Ohsawa I, Mori T, et al. Protection against ischemic brain injury by protein therapeutics. Proc Natl Acad Sci USA 2002; 99: 17107-12.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 17107-17112
    • Asoh, S.1    Ohsawa, I.2    Mori, T.3
  • 65
    • 36949083936 scopus 로고
    • Coupling of phosphorylation to electron and hydrogen transfer by a chemi-osmotic type of mechanism
    • Mitchell P. Coupling of phosphorylation to electron and hydrogen transfer by a chemi-osmotic type of mechanism. Nature 1961; 191: 144-8.
    • (1961) Nature , vol.191 , pp. 144-148
    • Mitchell, P.1
  • 66
    • 0024422115 scopus 로고
    • Slip and leak in mitochondrial oxidative phosphorylation
    • Murphy MP. Slip and leak in mitochondrial oxidative phosphorylation. Biochim Biophys Acta 1989; 977: 123-41.
    • (1989) Biochim Biophys Acta , vol.977 , pp. 123-141
    • Murphy, M.P.1
  • 67
    • 0002055897 scopus 로고
    • Determination of the proton electrochemical gradient across biological membranes
    • Azzone GF, Pietrobon D, Zoratti M. Determination of the proton electrochemical gradient across biological membranes. Curr Top Bioenergy 1984; 13: 1-77.
    • (1984) Curr Top Bioenergy , vol.13 , pp. 1-77
    • Azzone, G.F.1    Pietrobon, D.2    Zoratti, M.3
  • 68
    • 0031106373 scopus 로고    scopus 로고
    • Labeling of mitochondrial proteins in living cells by the thiol probe thiobutyltriphenylphosphonium bromide
    • Burns RJ, Murphy MP. Labeling of mitochondrial proteins in living cells by the thiol probe thiobutyltriphenylphosphonium bromide. Arch Biochem Biophys 1997; 339: 33-9.
    • (1997) Arch Biochem Biophys , vol.339 , pp. 33-39
    • Burns, R.J.1    Murphy, M.P.2
  • 69
    • 0018337795 scopus 로고
    • The measurement of membrane potential and deltapH in cells, organelles, and vesicles
    • Rottenberg H. The measurement of membrane potential and deltapH in cells, organelles, and vesicles. Methods Enzymol 1979; 55: 547-69.
    • (1979) Methods Enzymol , vol.55 , pp. 547-569
    • Rottenberg, H.1
  • 70
    • 0024148694 scopus 로고
    • Mitochondrial membrane potential in living cells
    • Chen LB. Mitochondrial membrane potential in living cells. Annu Rev Cell Biol 1988; 4: 155-81.
    • (1988) Annu Rev Cell Biol , vol.4 , pp. 155-181
    • Chen, L.B.1
  • 71
    • 0030969942 scopus 로고    scopus 로고
    • Protein import into mitochondria
    • Neupert W. Protein import into mitochondria. Annu Rev Biochem 1997; 66: 863-17.
    • (1997) Annu Rev Biochem , vol.66 , pp. 863-917
    • Neupert, W.1
  • 72
    • 0029774146 scopus 로고    scopus 로고
    • The protein import system of mitochondria
    • Schatz GJ. The protein import system of mitochondria. J Biol Chem 1996; 271: 31763-66.
    • (1996) J Biol Chem , vol.271 , pp. 31763-31766
    • Schatz, G.J.1
  • 74
    • 0027963264 scopus 로고
    • The protein import machinery of the mitochondrial inner membrane
    • Pfanner N, Craig EA, Meijer M. The protein import machinery of the mitochondrial inner membrane. Trends Biochem Sci 1994; 19: 368-72.
    • (1994) Trends Biochem Sci , vol.19 , pp. 368-372
    • Pfanner, N.1    Craig, E.A.2    Meijer, M.3
  • 75
    • 4544237885 scopus 로고    scopus 로고
    • Targeting of low-molecular weight drugs to mammalian mitochondria
    • Weissig V, Bodapati SV, D'Souza GGM, et al. Targeting of low-molecular weight drugs to mammalian mitochondria. Drug Des Rev 2004; 1: 15-28.
    • (2004) Drug Des Rev , vol.1 , pp. 15-28
    • Weissig, V.1    Bodapati, S.V.2    D'Souza, G.G.M.3
  • 76
    • 33847273537 scopus 로고    scopus 로고
    • Electrotransfer as a non viral method of gene delivery
    • Favard C, Dean DS, Rols M-P. Electrotransfer as a non viral method of gene delivery. Curr Gene Ther 2007; 7:67-77.
    • (2007) Curr Gene Ther , vol.7 , pp. 67-77
    • Favard, C.1    Dean, D.S.2    Rols, M.-P.3
  • 77
    • 0031054053 scopus 로고    scopus 로고
    • Introduction of plasmid DNA into isolated mitochondria by electroporation
    • Collombet JM, Wheeler VC, Vogel F, Coutelle C. Introduction of plasmid DNA into isolated mitochondria by electroporation. J Biol Chem 1997; 272: 5342-7.
    • (1997) J Biol Chem , vol.272 , pp. 5342-5347
    • Collombet, J.M.1    Wheeler, V.C.2    Vogel, F.3    Coutelle, C.4
  • 78
    • 0030725412 scopus 로고    scopus 로고
    • Modification of the mouse mitochondrial genome by insertion of an exogenous gene
    • Wheeler VC, Aitken M, Coutelle C. Modification of the mouse mitochondrial genome by insertion of an exogenous gene. Gene 1997; 198: 203-9.
    • (1997) Gene , vol.198 , pp. 203-209
    • Wheeler, V.C.1    Aitken, M.2    Coutelle, C.3
  • 79
    • 0025222081 scopus 로고
    • Organelle transformation: Shoot first, ask questions later
    • Butow RA, Fox TD. Organelle transformation: shoot first, ask questions later. Trends Biochem Sci 1990; 15: 465-8.
    • (1990) Trends Biochem Sci , vol.15 , pp. 465-468
    • Butow, R.A.1    Fox, T.D.2
  • 80
    • 0035401236 scopus 로고    scopus 로고
    • Nonviral gene gherapy
    • Li S, Ma Z. Nonviral gene gherapy. Curr Gene Ther 2001; 1: 201-26.
    • (2001) Curr Gene Ther , vol.1 , pp. 201-226
    • Li, S.1    Ma, Z.2
  • 81
    • 0035797116 scopus 로고    scopus 로고
    • Cationic bolasomes with delocalized charge centers as mitochondria-specific DNA delivery systems
    • Weissig V, Torchilin VP. Cationic bolasomes with delocalized charge centers as mitochondria-specific DNA delivery systems. Adv Drug Deliv Rev 2001; 49: 127-49.
    • (2001) Adv Drug Deliv Rev , vol.49 , pp. 127-149
    • Weissig, V.1    Torchilin, V.P.2
  • 82
    • 0004207663 scopus 로고    scopus 로고
    • Selective targeting of an antioxidant to mitochondria
    • Smith RAJ, Porteous CM, Coulter CV, et al. Selective targeting of an antioxidant to mitochondria. Eur J Biochem 1999; 263: 709-16.
    • (1999) Eur J Biochem , vol.263 , pp. 709-716
    • Smith, R.A.J.1    Porteous, C.M.2    Coulter, C.V.3
  • 83
    • 0035895888 scopus 로고    scopus 로고
    • Selective targeting of a redox-active ubiquinone to mitochondria within cells
    • Kelso GF, Porteous CM, Coulter CV, et al. Selective targeting of a redox-active ubiquinone to mitochondria within cells. J Biol Chem 2001; 276: 4588-96.
    • (2001) J Biol Chem , vol.276 , pp. 4588-4596
    • Kelso, G.F.1    Porteous, C.M.2    Coulter, C.V.3
  • 84
    • 20444392739 scopus 로고    scopus 로고
    • Interactions of mitochondria-targeted and untargeted ubiquinones with the mitochondrial respiratory chain and reactive oxygen species. Implications for the use of exogenous ubiquinones as therapies and experimental tools
    • James AM, Cochemé HM, Smith RA, Murphy MP. Interactions of mitochondria-targeted and untargeted ubiquinones with the mitochondrial respiratory chain and reactive oxygen species. Implications for the use of exogenous ubiquinones as therapies and experimental tools. J Biol Chem 2005; 280: 21295-312.
    • (2005) J Biol Chem , vol.280 , pp. 21295-21312
    • James, A.M.1    Cochemé, H.M.2    Smith, R.A.3    Murphy, M.P.4
  • 86
    • 21244448078 scopus 로고    scopus 로고
    • Synthesis and characterization of a triphenylphosphonium-conjugated peroxidase mimetic: Insights into the interaction of ebselen with mitochondria
    • Filipovska A, Kelso GF, Brown SE, Beer SM, Smith RA, Murphy MP. Synthesis and characterization of a triphenylphosphonium-conjugated peroxidase mimetic: Insights into the interaction of ebselen with mitochondria. J Biol Chem 2005; 280: 24113-26.
    • (2005) J Biol Chem , vol.280 , pp. 24113-24126
    • Filipovska, A.1    Kelso, G.F.2    Brown, S.E.3    Beer, S.M.4    Smith, R.A.5    Murphy, M.P.6
  • 87
    • 33751103141 scopus 로고    scopus 로고
    • Accumulation of lipophilic dications by mitochondria and cells
    • Ross MF, Da Ros T, Blaikie FH, et al. Accumulation of lipophilic dications by mitochondria and cells. Biochem J 2006; 400: 199-208.
    • (2006) Biochem J , vol.400 , pp. 199-208
    • Ross, M.F.1    Da Ros, T.2    Blaikie, F.H.3
  • 88
    • 67349283471 scopus 로고    scopus 로고
    • An attempt to prevent senescence: A mitochondrial approach. Biochim et Biophys Acta (BBA)
    • Skulachev VP, Anisimov VN, Antonenko YN, et al. An attempt to prevent senescence: a mitochondrial approach. Biochim et Biophys Acta (BBA) - Bioenergetics 2009; 1787: 437-61.
    • (2009) Bioenergetics , vol.1787 , pp. 437-461
    • Skulachev, V.P.1    Anisimov, V.N.2    Antonenko, Y.N.3
  • 89
    • 0035339611 scopus 로고    scopus 로고
    • Targeting peptide nucleic acid (PNA) oligomers to mitochondria within cells by conjugation to lipophilic cations: Implications for mitochondrial DNA replication, expression and disease
    • Muratovska A, Lightowlers RN, Taylor RW, et al. Targeting peptide nucleic acid (PNA) oligomers to mitochondria within cells by conjugation to lipophilic cations: implications for mitochondrial DNA replication, expression and disease. Nucleic Acids Res 2001; 29: 1852-63.
    • (2001) Nucleic Acids Res , vol.29 , pp. 1852-1863
    • Muratovska, A.1    Lightowlers, R.N.2    Taylor, R.W.3
  • 90
    • 0030872907 scopus 로고    scopus 로고
    • Targeting bioactive compounds to mitochondria
    • Murphy MP. Targeting bioactive compounds to mitochondria. Trends Biotechnol 1997; 15: 326-30.
    • (1997) Trends Biotechnol , vol.15 , pp. 326-330
    • Murphy, M.P.1
  • 91
    • 0024317248 scopus 로고
    • Tight folding of a passenger protein can interfere with the targeting function of a mitochondrial presequence
    • Verner K, Lemire BD. Tight folding of a passenger protein can interfere with the targeting function of a mitochondrial presequence. EMBO J 1989; 8: 1491-5.
    • (1989) EMBO J , vol.8 , pp. 1491-1495
    • Verner, K.1    Lemire, B.D.2
  • 92
    • 0038365420 scopus 로고    scopus 로고
    • Targeted delivery of DNA to the mitochondrial compartment via import sequence conjugated peptide nucleic acid
    • Flierl A, Jackson C, Cottrell B, et al. Targeted delivery of DNA to the mitochondrial compartment via import sequence conjugated peptide nucleic acid. Mol Ther 2003; 7: 550-7.
    • (2003) Mol Ther , vol.7 , pp. 550-557
    • Flierl, A.1    Jackson, C.2    Cottrell, B.3
  • 93
    • 0028804570 scopus 로고
    • Transfection of mitochondria: Strategy towards a gene therapy of mitochondrial DNA diseases
    • Seibel P, Trappe J, Villani G, et al. Transfection of mitochondria: strategy towards a gene therapy of mitochondrial DNA diseases. Nucleic Acids Res 1995; 23: 10-17.
    • (1995) Nucleic Acids Res , vol.23 , pp. 10-17
    • Seibel, P.1    Trappe, J.2    Villani, G.3
  • 94
    • 0024536726 scopus 로고
    • DNA-protein conjugates can enter mitochondria via the protein import pathway
    • Vestweber D, Schatz G. DNA-protein conjugates can enter mitochondria via the protein import pathway. Nature 1989; 338: 170-2.
    • (1989) Nature , vol.338 , pp. 170-172
    • Vestweber, D.1    Schatz, G.2
  • 95
    • 13844317215 scopus 로고    scopus 로고
    • TAT-mediated protein transduction and targeted delivery of fusion proteins into mitochondria of breast cancer cells
    • Shokolenko IN, Alexeyev MF, LeDoux SP, Wilson GL. TAT-mediated protein transduction and targeted delivery of fusion proteins into mitochondria of breast cancer cells. DNA Repair (Amst) 2005; 4: 511-8.
    • (2005) DNA Repair (Amst) , vol.4 , pp. 511-518
    • Shokolenko, I.N.1    Alexeyev, M.F.2    LeDoux, S.P.3    Wilson, G.L.4
  • 96
    • 33749023859 scopus 로고    scopus 로고
    • Low molecular weight polyethylenimine-mitochondrial leader peptide conjugate for DNA delivery to mitochondria
    • Choi JS, Choi MJ, Ko KS, et al. Low molecular weight polyethylenimine-mitochondrial leader peptide conjugate for DNA delivery to mitochondria. Bull Korean Chem Soc 2006; 27: 1335-40.
    • (2006) Bull Korean Chem Soc , vol.27 , pp. 1335-1340
    • Choi, J.S.1    Choi, M.J.2    Ko, K.S.3
  • 99
    • 0029949266 scopus 로고    scopus 로고
    • Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection
    • Xu Y, Szoka FC. Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection. Biochemistry 1996; 35: 5616-23.
    • (1996) Biochemistry , vol.35 , pp. 5616-5623
    • Xu, Y.1    Szoka, F.C.2
  • 100
    • 0031916033 scopus 로고    scopus 로고
    • DQAsomes: A novel potential drug and gene delivery system made from Dequalinium
    • Weissig V, Lasch J, Erdos G, et al. DQAsomes: a novel potential drug and gene delivery system made from Dequalinium. Pharm Res 1998; 15: 334-7.
    • (1998) Pharm Res , vol.15 , pp. 334-337
    • Weissig, V.1    Lasch, J.2    Erdos, G.3
  • 101
    • 0034003553 scopus 로고    scopus 로고
    • Selective DNA release from DQAsome/DNA complexes at mitochondria-like membranes
    • Weissig V, Lizano C, Torchilin VP. Selective DNA release from DQAsome/DNA complexes at mitochondria-like membranes. Drug Deliv 2000; 7: 1-5.
    • (2000) Drug Deliv , vol.7 , pp. 1-5
    • Weissig, V.1    Lizano, C.2    Torchilin, V.P.3
  • 102
    • 0035839167 scopus 로고    scopus 로고
    • DQAsome/DNA complexes release DNA upon contact with isolated mouse liver mitochondria
    • Weissig V, D'Souza GG, Torchilin VP. DQAsome/DNA complexes release DNA upon contact with isolated mouse liver mitochondria. J Control Rel 2001; 75: 401-8.
    • (2001) J Control Rel , vol.75 , pp. 401-408
    • Weissig, V.1    D'Souza, G.G.2    Torchilin, V.P.3
  • 104
    • 0032586976 scopus 로고    scopus 로고
    • Dequalinium vesicles form stable complexes with plasmid DNA which are protected from DNase attack
    • Lasch J, Meye A, Taubert H, et al. Dequalinium vesicles form stable complexes with plasmid DNA which are protected from DNase attack. Biol Chem 1999; 380: 647-52.
    • (1999) Biol Chem , vol.380 , pp. 647-652
    • Lasch, J.1    Meye, A.2    Taubert, H.3
  • 105
    • 26444444018 scopus 로고    scopus 로고
    • Mitochondrial leader sequence-plasmid DNA conjugates delivered into mammalian cells by DQAsomes co-localize with mitochondria
    • D'Souza GG, Boddapati SV, Weissig V. Mitochondrial leader sequence-plasmid DNA conjugates delivered into mammalian cells by DQAsomes co-localize with mitochondria. Mitochondrion 2005; 5: 352-8.
    • (2005) Mitochondrion , vol.5 , pp. 352-358
    • D'Souza, G.G.1    Boddapati, S.V.2    Weissig, V.3
  • 106
    • 0023447252 scopus 로고
    • Lipofection: A highly efficient, lipid-mediated DNA-transfection procedure
    • Felgner PL , Gadek TR , Holm M , et al. Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure. Proc Natl Acad Sci USA 1987; 84: 7413-7.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 7413-7417
    • Felgner, P.L.1    Gadek, T.R.2    Holm, M.3
  • 107
    • 34247855110 scopus 로고    scopus 로고
    • Nonviral gene delivery: What we know and what is next
    • Gao X, Kim KS, Liu D. Nonviral gene delivery: What we know and what is next. AAPS J 2007; 9: E92-104.
    • AAPS , vol.J 2007 , Issue.9
    • Gao, X.1    Kim, K.S.2    Liu, D.3
  • 108
    • 12344302096 scopus 로고    scopus 로고
    • Targeted drug delivery to mammalian mitochondria in living cells
    • Weissig V. Targeted drug delivery to mammalian mitochondria in living cells. Expert Opin Drug Deliv 2005; 2: 89-102.
    • (2005) Expert Opin Drug Deliv , vol.2 , pp. 89-102
    • Weissig, V.1
  • 109
    • 69949176886 scopus 로고    scopus 로고
    • Cell-selective mitochondrial targeting: A new approach for cancer therapy
    • Vaidya B, Paliwal R, Rai S, et al. Cell-selective mitochondrial targeting: A new approach for cancer therapy. Cancer Ther 2009; 7(A): 141-8.
    • (2009) Cancer Ther , vol.7 , Issue.A , pp. 141-148
    • Vaidya, B.1    Paliwal, R.2    Rai, S.3


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