Polymer-based gene delivery: A current review on the uptake and intracellular trafficking of polyplexes

Current Gene Therapy

Volumn 8, Issue 5, 2008, Pages 335-352

  Midoux, Patrick ^a   Breuzard, Gilles ^a   Gomez, Jean Pierre ^a   Pichon, Chantal ^a  

^a UNIVERSITÉ D'ORLÉANS   (France)

Author keywords

Cationic polymers; Cellular imaging; Confocal microscopy; Endocytosis; Gene delivery; Histidine; Non viral gene transfer; Nuclear import; PEI; Polyplexes

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; AMILORIDE; CATIONIC LIPID; CHITOSAN; CHLORPROMAZINE; CHOLERA TOXIN B SUBUNIT; CHONDROITIN SULFATE; CLATHRIN; DERMATAN SULFATE; FILIPIN; GLYCOSAMINOGLYCAN; HEPARIN; HISTIDINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPID; LIPOPLEX; METHYL BETA CYCLODEXTRIN; NOCODAZOLE; NYSTATIN; PLASMID DNA; POLYAMIDOAMINE; POLYARGININE; POLYETHYLENEIMINE; POLYLYSINE; POLYMER; POLYSACCHARIDE; RAB PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG; UNINDEXED DRUG; WORTMANNIN; CATION;

CAVEOLA; CELL CYCLE; CELL TRANSPORT; COATED VESICLE; CONFOCAL MICROSCOPY; DRUG MECHANISM; ENDOCYTOSIS; FLOW CYTOMETRY; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENE DELIVERY SYSTEM; GENE INSERTION; GENETIC TRANSFECTION; HUMAN; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; NUCLEAR IMPORT; NUCLEOTIDE SEQUENCE; PHAGOCYTOSIS; PINOCYTOSIS; POLARIZATION; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; REVIEW; ACTIVE TRANSPORT; CELL POLARITY; CHEMISTRY; DRUG DELIVERY SYSTEM; GENE THERAPY; GENETICS; INTRACELLULAR FLUID; METABOLISM; METHODOLOGY; PLASMID;

BIOLOGICAL TRANSPORT, ACTIVE; CATIONS; CAVEOLAE; CELL CYCLE; CELL POLARITY; CLATHRIN; DRUG DELIVERY SYSTEMS; ENDOCYTOSIS; GENE THERAPY; GLYCOSAMINOGLYCANS; HUMANS; INTRACELLULAR FLUID; PHAGOCYTOSIS; PINOCYTOSIS; PLASMIDS; POLYMERS;

EID: 59249105606     PISSN: 15665232     EISSN: None     Source Type: Journal    
DOI: 10.2174/156652308786071014     Document Type: Review

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