메뉴 건너뛰기




Volumn 58, Issue 1, 2006, Pages 32-45

Uptake pathways and subsequent intracellular trafficking in nonviral gene delivery

Author keywords

[No Author keywords available]

Indexed keywords

1,2 DIOLEOYL 3 TRIMETHYLAMMONIOPROPANE; AMMONIUM CHLORIDE; ARGININE DERIVATIVE; BAFILOMYCIN; CARRIER PROTEIN; CLATHRIN; CYTOCHALASIN; DIACYLGLYCEROL; DIOLEOYLPHOSPHATIDYLETHANOLAMINE; FILIPIN; GENISTEIN; LIPID; LIPOPLEX; LIPOSOME; LOW DENSITY LIPOPROTEIN; METHYL BETA CYCLODEXTRIN; METHYLAMINE; MONENSIN; NYSTATIN; PENETRATIN; PHORBOL ESTER DERIVATIVE; POLYETHYLENEIMINE; POLYLYSINE; POLYMER; POLYPLEX; PROTEIN VP22; STREPTOLYSIN O; TRANSACTIVATOR PROTEIN; TRANSFERRIN; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 33644593889     PISSN: 00316997     EISSN: None     Source Type: Journal    
DOI: 10.1124/pr.58.1.8     Document Type: Review
Times cited : (1119)

References (127)
  • 1
    • 1642443376 scopus 로고    scopus 로고
    • Quantitative three-dimensional analysis of the intracellular trafficking of plasmid DNA transfected by a nonviral gene delivery system using confocal laser scanning microscopy
    • Akita H, Ito R, Khalil IA, Futaki S, and Harashima H (2004) Quantitative three-dimensional analysis of the intracellular trafficking of plasmid DNA transfected by a nonviral gene delivery system using confocal laser scanning microscopy. Mol Ther 9:443-451.
    • (2004) Mol Ther , vol.9 , pp. 443-451
    • Akita, H.1    Ito, R.2    Khalil, I.A.3    Futaki, S.4    Harashima, H.5
  • 3
    • 0023659741 scopus 로고
    • Large unilamellar liposomes with low uptake into the reticuloendothelial system
    • Allen TM and Chonn A (1987) Large unilamellar liposomes with low uptake into the reticuloendothelial system. FEBS Lett 223:42-46.
    • (1987) FEBS Lett , vol.223 , pp. 42-46
    • Allen, T.M.1    Chonn, A.2
  • 6
    • 0026545612 scopus 로고
    • Potocytosis: Sequestration and transport of small molecules by caveolae
    • Anderson RG, Kamen BA, Rothberg KG, and Lacey SW (1992) Potocytosis: sequestration and transport of small molecules by caveolae. Science (Wash DC) 255:410-411.
    • (1992) Science (Wash DC) , vol.255 , pp. 410-411
    • Anderson, R.G.1    Kamen, B.A.2    Rothberg, K.G.3    Lacey, S.W.4
  • 7
    • 0027432424 scopus 로고
    • Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: The role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses
    • Arcaro A and Wymann MP (1993) Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses. Biochem J 296 (Pt 2):297-301.
    • (1993) Biochem J , vol.296 , Issue.2 PART , pp. 297-301
    • Arcaro, A.1    Wymann, M.P.2
  • 8
    • 0034649660 scopus 로고    scopus 로고
    • Endocytosis and the development of cell polarity in yeast require a dynamic F-actin cytoskeleton
    • Ayscough KR (2000) Endocytosis and the development of cell polarity in yeast require a dynamic F-actin cytoskeleton. Curr Biol 10:1587-1590.
    • (2000) Curr Biol , vol.10 , pp. 1587-1590
    • Ayscough, K.R.1
  • 10
    • 0027758627 scopus 로고
    • Introduction of antisense oligonucleotides into cells by permeabilization with streptolysin O
    • Barry EL, Gesek FA, and Friedman PA (1993) Introduction of antisense oligonucleotides into cells by permeabilization with streptolysin O. Biotechniques 15:1016-1018, 1020.
    • (1993) Biotechniques , vol.15 , pp. 1016-1018
    • Barry, E.L.1    Gesek, F.A.2    Friedman, P.A.3
  • 11
    • 0000893449 scopus 로고
    • Efficient gene transfer into mammalian primary endocrine cells with lipopolyamine-coated DNA
    • Behr JP, Demeneix B, Loeffler JP, and Perez-Mutul J (1989) Efficient gene transfer into mammalian primary endocrine cells with lipopolyamine-coated DNA. Proc Natl Acad Sci USA 86:6982-6986.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 6982-6986
    • Behr, J.P.1    Demeneix, B.2    Loeffler, J.P.3    Perez-Mutul, J.4
  • 12
    • 0027242052 scopus 로고
    • Electroporation enhances c-myc antisense oligodeoxynucleotide efficacy
    • Bergan R, Connell Y, Fahmy B, and Neckers L (1993) Electroporation enhances c-myc antisense oligodeoxynucleotide efficacy. Nucleic Acids Res 21:3567-3573.
    • (1993) Nucleic Acids Res , vol.21 , pp. 3567-3573
    • Bergan, R.1    Connell, Y.2    Fahmy, B.3    Neckers, L.4
  • 15
    • 13844256698 scopus 로고    scopus 로고
    • Tat peptide-mediated cellular delivery: Back to basics
    • Brooks H, Lebleu B, and Vives E (2005) Tat peptide-mediated cellular delivery: back to basics. Adv Drug Deliv Rev 57:559-577.
    • (2005) Adv Drug Deliv Rev , vol.57 , pp. 559-577
    • Brooks, H.1    Lebleu, B.2    Vives, E.3
  • 16
    • 21644487837 scopus 로고    scopus 로고
    • Folate receptor-mediated gene delivery using folate-poly(ethylene glycol)-poly(L-lysine) conjugate
    • Cho KC, Kim SH, Jeong JH, and Park TG (2005) Folate receptor-mediated gene delivery using folate-poly(ethylene glycol)-poly(L-lysine) conjugate. Macromol Biosci 5:512-519.
    • (2005) Macromol Biosci , vol.5 , pp. 512-519
    • Cho, K.C.1    Kim, S.H.2    Jeong, J.H.3    Park, T.G.4
  • 18
    • 0037422066 scopus 로고    scopus 로고
    • Regulated portals of entry into the cell
    • Conner SD and Schmid SL (2003) Regulated portals of entry into the cell. Nature (Lond) 422:37-44.
    • (2003) Nature (Lond) , vol.422 , pp. 37-44
    • Conner, S.D.1    Schmid, S.L.2
  • 19
    • 0025313130 scopus 로고
    • Transferrin-polycation-mediated introduction of DNA into human leukemic cells: Stimulation by agents that affect the survival of transfected DNA or modulate transferrin receptor levels
    • Cotten M, Langle-Rouault F, Kirlappos H, Wagner E, Mechtler K, Zenke M, Beug H, and Birnstiel ML (1990) Transferrin-polycation-mediated introduction of DNA into human leukemic cells: stimulation by agents that affect the survival of transfected DNA or modulate transferrin receptor levels. Proc Natl Acad Sci USA 87:4033-4037.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 4033-4037
    • Cotten, M.1    Langle-Rouault, F.2    Kirlappos, H.3    Wagner, E.4    Mechtler, K.5    Zenke, M.6    Beug, H.7    Birnstiel, M.L.8
  • 20
    • 0022486185 scopus 로고
    • Lipid polymorphism and the roles of lipids in membranes
    • Cullis PR, Hope MJ, and Tilcock CP (1986) Lipid polymorphism and the roles of lipids in membranes. Chem Phys Lipids 40:127-144.
    • (1986) Chem Phys Lipids , vol.40 , pp. 127-144
    • Cullis, P.R.1    Hope, M.J.2    Tilcock, C.P.3
  • 21
    • 0028036513 scopus 로고
    • Induction of mutant dynamin specifically blocks endocytic coated vesicle formation
    • Damke H, Baba T, Warnock DE, and Schmid SL (1994) Induction of mutant dynamin specifically blocks endocytic coated vesicle formation. J Cell Biol 127:915-934.
    • (1994) J Cell Biol , vol.127 , pp. 915-934
    • Damke, H.1    Baba, T.2    Warnock, D.E.3    Schmid, S.L.4
  • 23
    • 0029982569 scopus 로고    scopus 로고
    • Cell internalization of the third helix of the Antennapedia homeodomain is receptor-independent
    • Derossi D, Calvet S, Trembleau A, Brunissen A, Chassaing G, and Prochiantz A (1996) Cell internalization of the third helix of the Antennapedia homeodomain is receptor-independent. J Biol Chem 271:18188-18193.
    • (1996) J Biol Chem , vol.271 , pp. 18188-18193
    • Derossi, D.1    Calvet, S.2    Trembleau, A.3    Brunissen, A.4    Chassaing, G.5    Prochiantz, A.6
  • 24
    • 0034739609 scopus 로고    scopus 로고
    • Novel non-endocytic delivery of antisense oligonucleotides
    • Dokka S and Rojanasakul Y (2000) Novel non-endocytic delivery of antisense oligonucleotides. Adv Drug Deliv Rev 44:35-49.
    • (2000) Adv Drug Deliv Rev , vol.44 , pp. 35-49
    • Dokka, S.1    Rojanasakul, Y.2
  • 25
    • 0040117958 scopus 로고    scopus 로고
    • Bafilomycins and concanamycins as inhibitors of V-ATPases and P-ATPases
    • Drose S and Altendorf K (1997) Bafilomycins and concanamycins as inhibitors of V-ATPases and P-ATPases. J Exp Biol 200:1-8.
    • (1997) J Exp Biol , vol.200 , pp. 1-8
    • Drose, S.1    Altendorf, K.2
  • 26
    • 0024094917 scopus 로고
    • The effects of variations in the number and sequence of targeting signals on nuclear uptake
    • Dworetzky SI, Lanford RE, and Feldherr CM (1988) The effects of variations in the number and sequence of targeting signals on nuclear uptake. J Cell Biol 107:1279-1287.
    • (1988) J Cell Biol , vol.107 , pp. 1279-1287
    • Dworetzky, S.I.1    Lanford, R.E.2    Feldherr, C.M.3
  • 28
    • 0029067792 scopus 로고
    • The role of dioleoyl phosphatidylethanolamine in cationic liposome mediated gene transfer
    • Farhood H, Serbina N, and Huang L (1995) The role of dioleoyl phosphatidylethanolamine in cationic liposome mediated gene transfer. Biochim Biophys Acta 1235:289-295.
    • (1995) Biochim Biophys Acta , vol.1235 , pp. 289-295
    • Farhood, H.1    Serbina, N.2    Huang, L.3
  • 31
    • 0042355293 scopus 로고    scopus 로고
    • Caveolae-mediated internalization of extracellular HIV-1 tat fusion proteins visualized in real time
    • Ferrari A, Pellegrini V, Arcangeli C, Fittipaldi A, Giacca M, and Beltram F (2003) Caveolae-mediated internalization of extracellular HIV-1 tat fusion proteins visualized in real time. Mol Ther 8:284-294.
    • (2003) Mol Ther , vol.8 , pp. 284-294
    • Ferrari, A.1    Pellegrini, V.2    Arcangeli, C.3    Fittipaldi, A.4    Giacca, M.5    Beltram, F.6
  • 33
    • 0030071910 scopus 로고    scopus 로고
    • Endocytosis and intracellular processing accompanying transfection mediated by cationic liposomes
    • Friend DS, Papahadjopoulos D, and Debs RJ (1996) Endocytosis and intracellular processing accompanying transfection mediated by cationic liposomes. Biochim Biophys Acta 1278:41-50.
    • (1996) Biochim Biophys Acta , vol.1278 , pp. 41-50
    • Friend, D.S.1    Papahadjopoulos, D.2    Debs, R.J.3
  • 34
    • 0034139820 scopus 로고    scopus 로고
    • Actin assembly plays a variable, but not obligatory role in receptor-mediated endocytosis in mammalian cells
    • Fujimoto LM, Roth R, Heuser JE, and Schmid SL (2000) Actin assembly plays a variable, but not obligatory role in receptor-mediated endocytosis in mammalian cells. Traffic 1:161-171.
    • (2000) Traffic , vol.1 , pp. 161-171
    • Fujimoto, L.M.1    Roth, R.2    Heuser, J.E.3    Schmid, S.L.4
  • 37
    • 4344697827 scopus 로고    scopus 로고
    • Macropinocytosis of polyplexes and recycling of plasmid via the clathrin-dependent pathway impair the transfection efficiency of human hepatocarcinoma cells
    • Goncalves C, Mennesson E, Fuchs R, Gorvel JP, Midoux P, and Pichon C (2004) Macropinocytosis of polyplexes and recycling of plasmid via the clathrin-dependent pathway impair the transfection efficiency of human hepatocarcinoma cells. Mol Ther 10:373-385.
    • (2004) Mol Ther , vol.10 , pp. 373-385
    • Goncalves, C.1    Mennesson, E.2    Fuchs, R.3    Gorvel, J.P.4    Midoux, P.5    Pichon, C.6
  • 38
    • 13844298046 scopus 로고    scopus 로고
    • Intracellular delivery of large molecules and small particles by cell-penetrating proteins and peptides
    • Gupta B, Levchenko TS, and Torchilin VP (2005) Intracellular delivery of large molecules and small particles by cell-penetrating proteins and peptides. Adv Drug Deliv Rev 57:637-651.
    • (2005) Adv Drug Deliv Rev , vol.57 , pp. 637-651
    • Gupta, B.1    Levchenko, T.S.2    Torchilin, V.P.3
  • 39
  • 40
    • 0024595608 scopus 로고
    • Hypertonic media inhibit receptor-mediated endocytosis by blocking clathrin-coated pit formation
    • Heuser JE and Anderson RG (1989) Hypertonic media inhibit receptor-mediated endocytosis by blocking clathrin-coated pit formation. J Cell Biol 108:389-400.
    • (1989) J Cell Biol , vol.108 , pp. 389-400
    • Heuser, J.E.1    Anderson, R.G.2
  • 41
    • 0028211773 scopus 로고
    • The coated pit and macropinocytic pathways serve distinct endosome populations
    • Hewlett LJ, Prescott AR, and Watts C (1994) The coated pit and macropinocytic pathways serve distinct endosome populations. J Cell Biol 124:689-703.
    • (1994) J Cell Biol , vol.124 , pp. 689-703
    • Hewlett, L.J.1    Prescott, A.R.2    Watts, C.3
  • 42
    • 0025773499 scopus 로고
    • Liposomes for the transformation of eukaryotic cells
    • Hug P and Sleight RG (1991) Liposomes for the transformation of eukaryotic cells. Biochim Biophys Acta 1097:1-17.
    • (1991) Biochim Biophys Acta , vol.1097 , pp. 1-17
    • Hug, P.1    Sleight, R.G.2
  • 43
    • 0030340799 scopus 로고    scopus 로고
    • Spermidine-condensed DNA and cone-shaped lipids improve delivery and expression of exogenous DNA transfer by liposomes
    • Ibanez M, Gariglio P, Chavez P, Santiago R, Wong C, and Baeza I (1996) Spermidine-condensed DNA and cone-shaped lipids improve delivery and expression of exogenous DNA transfer by liposomes. Biochem Cell Biol 74:633-643.
    • (1996) Biochem Cell Biol , vol.74 , pp. 633-643
    • Ibanez, M.1    Gariglio, P.2    Chavez, P.3    Santiago, R.4    Wong, C.5    Baeza, I.6
  • 44
    • 0029797971 scopus 로고    scopus 로고
    • Regulation of protein transport to the nucleus: Central role of phosphorylation
    • Jans DA and Hubner S (1996) Regulation of protein transport to the nucleus: central role of phosphorylation. Physiol Rev 76:651-685.
    • (1996) Physiol Rev , vol.76 , pp. 651-685
    • Jans, D.A.1    Hubner, S.2
  • 45
    • 0027764386 scopus 로고
    • Endosome acidification and receptor trafficking: Bafilomycin A1 slows receptor externalization by a mechanism involving the receptor's internalization motif
    • Johnson LS, Dunn KW, Pytowski B, and McGraw TE (1993) Endosome acidification and receptor trafficking: bafilomycin A1 slows receptor externalization by a mechanism involving the receptor's internalization motif. Mol Biol Cell 4:1251-1266.
    • (1993) Mol Biol Cell , vol.4 , pp. 1251-1266
    • Johnson, L.S.1    Dunn, K.W.2    Pytowski, B.3    McGraw, T.E.4
  • 46
  • 47
    • 0344120637 scopus 로고    scopus 로고
    • Pharmacokinetic and pharmacodynamic considerations in gene therapy
    • Kamiya H, Akita H, and Harashima H (2003) Pharmacokinetic and pharmacodynamic considerations in gene therapy. Drug Discov Today 8:990-996.
    • (2003) Drug Discov Today , vol.8 , pp. 990-996
    • Kamiya, H.1    Akita, H.2    Harashima, H.3
  • 48
    • 0036429187 scopus 로고    scopus 로고
    • Visualization of intracellular trafficking of exogenous DNA delivered by cationic liposomes
    • Kamiya H, Fujimura Y, Matsuoka I, and Harashima H (2002) Visualization of intracellular trafficking of exogenous DNA delivered by cationic liposomes. Biochem Biophys Res Commun 298:591-597.
    • (2002) Biochem Biophys Res Commun , vol.298 , pp. 591-597
    • Kamiya, H.1    Fujimura, Y.2    Matsuoka, I.3    Harashima, H.4
  • 49
    • 11844268027 scopus 로고    scopus 로고
    • Cationic TAT peptide transduction domain enters cells by macropinocytosis
    • Kaplan IM, Wadia JS, and Dowdy SF (2005) Cationic TAT peptide transduction domain enters cells by macropinocytosis. J Control Release 102:247-253.
    • (2005) J Control Release , vol.102 , pp. 247-253
    • Kaplan, I.M.1    Wadia, J.S.2    Dowdy, S.F.3
  • 50
    • 2642570239 scopus 로고    scopus 로고
    • Effect of cationic charge on receptor-mediated transfection using mannosylated cationic liposome/plasmid DNA complexes following the intravenous administration in mice
    • Kawakami S, Hattori Y, Lu Y, Higuchi Y, Yamashita F, and Hashida M (2004) Effect of cationic charge on receptor-mediated transfection using mannosylated cationic liposome/plasmid DNA complexes following the intravenous administration in mice. Pharmazie 59:405-408.
    • (2004) Pharmazie , vol.59 , pp. 405-408
    • Kawakami, S.1    Hattori, Y.2    Lu, Y.3    Higuchi, Y.4    Yamashita, F.5    Hashida, M.6
  • 51
    • 1642578411 scopus 로고    scopus 로고
    • Mechanism of improved gene transfer by the N-terminal stearylation of octaarginine: Enhanced cellular association by hydrophobic core formation
    • Khalil IA, Futaki S, Niwa M, Baba Y, Kaji N, Kamiya H, and Harashima H (2004) Mechanism of improved gene transfer by the N-terminal stearylation of octaarginine: enhanced cellular association by hydrophobic core formation. Gene Ther 11:636-644.
    • (2004) Gene Ther , vol.11 , pp. 636-644
    • Khalil, I.A.1    Futaki, S.2    Niwa, M.3    Baba, Y.4    Kaji, N.5    Kamiya, H.6    Harashima, H.7
  • 52
    • 33645640345 scopus 로고    scopus 로고
    • High density of octaarginine stimulates macropinocytosis leading to efficient intracellular trafficking for gene expression
    • in press
    • Khalil IA, Kogure K, Futaki S, and Harashima H (2006) High density of octaarginine stimulates macropinocytosis leading to efficient intracellular trafficking for gene expression. J Biol Chem, in press.
    • (2006) J Biol Chem
    • Khalil, I.A.1    Kogure, K.2    Futaki, S.3    Harashima, H.4
  • 53
    • 0035286969 scopus 로고    scopus 로고
    • Polyethylenimine-mediated gene delivery: A mechanistic study
    • Kichler A, Leborgne C, Coeytaux E, and Danos O (2001) Polyethylenimine-mediated gene delivery: a mechanistic study. J Gene Med 3:135-144.
    • (2001) J Gene Med , vol.3 , pp. 135-144
    • Kichler, A.1    Leborgne, C.2    Coeytaux, E.3    Danos, O.4
  • 54
    • 0032496676 scopus 로고    scopus 로고
    • Identification of proteins mediating clearance of liposomes using a liver perfusion system
    • Kiwada H, Matsuo H, and Harashima H (1998) Identification of proteins mediating clearance of liposomes using a liver perfusion system. Adv Drug Deliv Rev 32:61-79.
    • (1998) Adv Drug Deliv Rev , vol.32 , pp. 61-79
    • Kiwada, H.1    Matsuo, H.2    Harashima, H.3
  • 55
    • 0031782223 scopus 로고    scopus 로고
    • Effects of polyethyleneimine on endocytosis and lysosome stability
    • Klemm AR, Young D, and Lloyd JB (1998) Effects of polyethyleneimine on endocytosis and lysosome stability. Biochem Pharmacol 56:41-46.
    • (1998) Biochem Pharmacol , vol.56 , pp. 41-46
    • Klemm, A.R.1    Young, D.2    Lloyd, J.B.3
  • 56
    • 0025880464 scopus 로고
    • Assignment of G-protein subtypes to specific receptors inducing inhibition of calcium currents
    • Kleuss C, Hescheler J, Ewel C, Rosenthal W, Schultz G, and Wittig B (1991) Assignment of G-protein subtypes to specific receptors inducing inhibition of calcium currents. Nature (Lond) 353:43-48.
    • (1991) Nature (Lond) , vol.353 , pp. 43-48
    • Kleuss, C.1    Hescheler, J.2    Ewel, C.3    Rosenthal, W.4    Schultz, G.5    Wittig, B.6
  • 57
    • 3242657221 scopus 로고    scopus 로고
    • Development of a non-viral multifunctional envelope-type nano device by a novel lipid film hydration method
    • Kogure K, Moriguchi R, Sasaki K, Ueno M, Futaki S, and Harashima H (2004) Development of a non-viral multifunctional envelope-type nano device by a novel lipid film hydration method. J Control Release 98:317-323.
    • (2004) J Control Release , vol.98 , pp. 317-323
    • Kogure, K.1    Moriguchi, R.2    Sasaki, K.3    Ueno, M.4    Futaki, S.5    Harashima, H.6
  • 58
    • 3042857264 scopus 로고    scopus 로고
    • A model for non-viral gene delivery: Through syndecan adhesion molecules and powered by actin
    • Kopatz I, Remy JS, and Behr JP (2004) A model for non-viral gene delivery: through syndecan adhesion molecules and powered by actin. J Gene Med 6:769-776.
    • (2004) J Gene Med , vol.6 , pp. 769-776
    • Kopatz, I.1    Remy, J.S.2    Behr, J.P.3
  • 60
    • 0029117498 scopus 로고
    • The emergence of clathrin-independent pinocytic pathways
    • Lamaze C and Schmid SL (1995) The emergence of clathrin-independent pinocytic pathways. Curr Opin Cell Biol 7:573-580.
    • (1995) Curr Opin Cell Biol , vol.7 , pp. 573-580
    • Lamaze, C.1    Schmid, S.L.2
  • 61
    • 0020626609 scopus 로고
    • Depletion of intracellular potassium arrests coated pit formation and receptor-mediated endocytosis in fibroblasts
    • Larkin JM, Brown MS, Goldstein JL, and Anderson RG (1983) Depletion of intracellular potassium arrests coated pit formation and receptor-mediated endocytosis in fibroblasts. Cell 33:273-285.
    • (1983) Cell , vol.33 , pp. 273-285
    • Larkin, J.M.1    Brown, M.S.2    Goldstein, J.L.3    Anderson, R.G.4
  • 62
    • 0028585823 scopus 로고
    • Non-viral gene therapy
    • Ledley FD (1994) Non-viral gene therapy. Curr Opin Biotechnol 5:626-636.
    • (1994) Curr Opin Biotechnol , vol.5 , pp. 626-636
    • Ledley, F.D.1
  • 63
    • 0029932762 scopus 로고    scopus 로고
    • Folate-targeted, anionic liposome-entrapped polylysine-condensed DNA for tumor cell-specific gene transfer
    • Lee RJ and Huang L (1996) Folate-targeted, anionic liposome-entrapped polylysine-condensed DNA for tumor cell-specific gene transfer. J Biol Chem 271:8481-8487.
    • (1996) J Biol Chem , vol.271 , pp. 8481-8487
    • Lee, R.J.1    Huang, L.2
  • 65
    • 0033972869 scopus 로고    scopus 로고
    • Nonviral gene therapy: Promises and challenges
    • Li S and Huang L (2000) Nonviral gene therapy: promises and challenges. Gene Ther 7:31-34.
    • (2000) Gene Ther , vol.7 , pp. 31-34
    • Li, S.1    Huang, L.2
  • 66
    • 1942438703 scopus 로고    scopus 로고
    • GALA: A designed synthetic pH-responsive amphipathic peptide with applications in drug and gene delivery
    • Li W, Nicol F, and Szoka FC Jr (2004) GALA: a designed synthetic pH-responsive amphipathic peptide with applications in drug and gene delivery. Adv Drug Deliv Rev 56:967-985.
    • (2004) Adv Drug Deliv Rev , vol.56 , pp. 967-985
    • Li, W.1    Nicol, F.2    Szoka Jr., F.C.3
  • 68
    • 0042199010 scopus 로고    scopus 로고
    • Cell surface adherence and endocytosis of protein transduction domains
    • Lundberg M, Wikstrom S, and Johansson M (2003) Cell surface adherence and endocytosis of protein transduction domains. Mol Ther 8:143-150.
    • (2003) Mol Ther , vol.8 , pp. 143-150
    • Lundberg, M.1    Wikstrom, S.2    Johansson, M.3
  • 69
    • 0031013538 scopus 로고    scopus 로고
    • Loss of binding and entry of liposome-DNA complexes decreases transfection efficiency in differentiated airway epithelial cells
    • Matsui H, Johnson LG, Randell SH, and Boucher RC (1997) Loss of binding and entry of liposome-DNA complexes decreases transfection efficiency in differentiated airway epithelial cells. J Biol Chem 272:1117-1126.
    • (1997) J Biol Chem , vol.272 , pp. 1117-1126
    • Matsui, H.1    Johnson, L.G.2    Randell, S.H.3    Boucher, R.C.4
  • 70
    • 0035963866 scopus 로고    scopus 로고
    • The role of caveolae and caveolin in vesicle-dependent and vesicle-independent trafficking
    • Matveev S, Li X, Everson W, and Smart EJ (2001) The role of caveolae and caveolin in vesicle-dependent and vesicle-independent trafficking. Adv Drug Deliv Rev 49:237-250.
    • (2001) Adv Drug Deliv Rev , vol.49 , pp. 237-250
    • Matveev, S.1    Li, X.2    Everson, W.3    Smart, E.J.4
  • 72
    • 0042668823 scopus 로고    scopus 로고
    • Adenovirus endocytosis
    • Meier O and Greber UF (2003) Adenovirus endocytosis. J Gene Med 5:451-462.
    • (2003) J Gene Med , vol.5 , pp. 451-462
    • Meier, O.1    Greber, U.F.2
  • 73
    • 0029042717 scopus 로고
    • Mechanisms of nuclear protein import
    • Melchior F and Gerace L (1995) Mechanisms of nuclear protein import. Curr Opin Cell Biol 7:310-318.
    • (1995) Curr Opin Cell Biol , vol.7 , pp. 310-318
    • Melchior, F.1    Gerace, L.2
  • 74
    • 0022555867 scopus 로고
    • Acidification of the endocytic and exocytic pathways
    • Mellman I, Fuchs R, and Helenius A (1986) Acidification of the endocytic and exocytic pathways. Annu Rev Biochem 55:663-700.
    • (1986) Annu Rev Biochem , vol.55 , pp. 663-700
    • Mellman, I.1    Fuchs, R.2    Helenius, A.3
  • 75
    • 0028973126 scopus 로고
    • Membrane permeabilization by α-helical peptides: A flow cytometry study
    • Midoux P, Mayer R, and Monsigny M (1995) Membrane permeabilization by α-helical peptides: a flow cytometry study. Biochim Biophys Acta 1239:249-256.
    • (1995) Biochim Biophys Acta , vol.1239 , pp. 249-256
    • Midoux, P.1    Mayer, R.2    Monsigny, M.3
  • 76
    • 0029981092 scopus 로고    scopus 로고
    • Evidence for the role of proteoglycans in cation-mediated gene transfer
    • Mislick KA and Baldeschwieler JD (1996) Evidence for the role of proteoglycans in cation-mediated gene transfer. Proc Natl Acad Sci USA 93:12349-12354.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 12349-12354
    • Mislick, K.A.1    Baldeschwieler, J.D.2
  • 77
    • 0025240867 scopus 로고
    • Alteration of intracellular traffic by monensin; mechanism, specificity and relationship to toxicity
    • Mollenhauer HH, Morre DJ, and Rowe LD (1990) Alteration of intracellular traffic by monensin; mechanism, specificity and relationship to toxicity. Biochim Biophys Acta 1031:225-246.
    • (1990) Biochim Biophys Acta , vol.1031 , pp. 225-246
    • Mollenhauer, H.H.1    Morre, D.J.2    Rowe, L.D.3
  • 80
    • 0031750101 scopus 로고    scopus 로고
    • Filipin-dependent inhibition of cholera toxin: Evidence for toxin internalization and activation through caveolae-like domains
    • Orlandi PA and Fishman PH (1998) Filipin-dependent inhibition of cholera toxin: evidence for toxin internalization and activation through caveolae-like domains. J Cell Biol 141:905-915.
    • (1998) J Cell Biol , vol.141 , pp. 905-915
    • Orlandi, P.A.1    Fishman, P.H.2
  • 81
    • 0028138521 scopus 로고
    • Regulated internalization of caveolae
    • Parton RG, Joggerst B, and Simons K (1994) Regulated internalization of caveolae. J Cell Biol 127:1199-1215.
    • (1994) J Cell Biol , vol.127 , pp. 1199-1215
    • Parton, R.G.1    Joggerst, B.2    Simons, K.3
  • 82
    • 0035017308 scopus 로고    scopus 로고
    • Caveolar endocytosis of simian virus 40 reveals a new two-step vesicular-transport pathway to the ER
    • Pelkmans L, Kartenbeck J, and Helenius A (2001) Caveolar endocytosis of simian virus 40 reveals a new two-step vesicular-transport pathway to the ER. Nat Cell Biol 3:473-483.
    • (2001) Nat Cell Biol , vol.3 , pp. 473-483
    • Pelkmans, L.1    Kartenbeck, J.2    Helenius, A.3
  • 83
    • 0030896557 scopus 로고    scopus 로고
    • Biochemical and functional characterization of DNA complexes capable of targeting genes to hepatocytes via the asialoglycoprotein receptor
    • Perales JC, Grossmann GA, Molas M, Liu G, Ferkol T, Harpst J, Oda H, and Hanson RW (1997) Biochemical and functional characterization of DNA complexes capable of targeting genes to hepatocytes via the asialoglycoprotein receptor. J Biol Chem 272:7398-7407.
    • (1997) J Biol Chem , vol.272 , pp. 7398-7407
    • Perales, J.C.1    Grossmann, G.A.2    Molas, M.3    Liu, G.4    Ferkol, T.5    Harpst, J.6    Oda, H.7    Hanson, R.W.8
  • 84
    • 0036909567 scopus 로고    scopus 로고
    • Small molecules, big impact: A history of chemical inhibitors and the cytoskeleton
    • Peterson JR and Mitchison TJ (2002) Small molecules, big impact: a history of chemical inhibitors and the cytoskeleton. Chem Biol 9:1275-1285.
    • (2002) Chem Biol , vol.9 , pp. 1275-1285
    • Peterson, J.R.1    Mitchison, T.J.2
  • 85
    • 0028199067 scopus 로고
    • The influence of endosome-disruptive peptides on gene transfer using synthetic virus-like gene transfer systems
    • Plank C, Oberhauser B, Mechtler K, Koch C, and Wagner E (1994) The influence of endosome-disruptive peptides on gene transfer using synthetic virus-like gene transfer systems. J Biol Chem 269:12918-12924.
    • (1994) J Biol Chem , vol.269 , pp. 12918-12924
    • Plank, C.1    Oberhauser, B.2    Mechtler, K.3    Koch, C.4    Wagner, E.5
  • 86
    • 0032571392 scopus 로고    scopus 로고
    • Polyethylenimine but not cationic lipids promotes transgene delivery to the nucleus in mammalian cells
    • Pollard H, Remy JS, Loussouarn G, Demolombe S, Behr JP, and Escande D (1998) Polyethylenimine but not cationic lipids promotes transgene delivery to the nucleus in mammalian cells. J Biol Chem 273:7507-7511.
    • (1998) J Biol Chem , vol.273 , pp. 7507-7511
    • Pollard, H.1    Remy, J.S.2    Loussouarn, G.3    Demolombe, S.4    Behr, J.P.5    Escande, D.6
  • 87
    • 0031036238 scopus 로고    scopus 로고
    • Structure of DNA-cationic liposome complexes: DNA intercalation in multilamellar membranes in distinct interhelical packing regimes
    • Radler JO, Koltover I, Salditt T, and Safinya CR (1997) Structure of DNA-cationic liposome complexes: DNA intercalation in multilamellar membranes in distinct interhelical packing regimes. Science (Wash DC) 275:810-814.
    • (1997) Science (Wash DC) , vol.275 , pp. 810-814
    • Radler, J.O.1    Koltover, I.2    Salditt, T.3    Safinya, C.R.4
  • 88
    • 23844462026 scopus 로고    scopus 로고
    • Role of clathrin- and caveolae-mediated endocytosis in gene transfer mediated by lipo- and polyplexes
    • Rejman J, Bragonzi A, and Conese M (2005) Role of clathrin- and caveolae-mediated endocytosis in gene transfer mediated by lipo- and polyplexes. Mol Ther 12:468-474.
    • (2005) Mol Ther , vol.12 , pp. 468-474
    • Rejman, J.1    Bragonzi, A.2    Conese, M.3
  • 89
    • 1642575957 scopus 로고    scopus 로고
    • Size-dependent internalization of particles via the pathways of clathrin- and caveolae-mediated endocytosis
    • Rejman J, Oberle V, Zuhorn IS, and Hoekstra D (2004) Size-dependent internalization of particles via the pathways of clathrin- and caveolae-mediated endocytosis. Biochem J 377:159-169.
    • (2004) Biochem J , vol.377 , pp. 159-169
    • Rejman, J.1    Oberle, V.2    Zuhorn, I.S.3    Hoekstra, D.4
  • 90
    • 17644386231 scopus 로고    scopus 로고
    • Cellular uptake of unconjugated TAT peptide involves clathrin-dependent endocytosis and heparan sulfate receptors
    • Richard JP, Melikov K, Brooks H, Prevot P, Lebleu B, and Chernomordik LV (2005) Cellular uptake of unconjugated TAT peptide involves clathrin-dependent endocytosis and heparan sulfate receptors. J Biol Chem 280:15300-15306.
    • (2005) J Biol Chem , vol.280 , pp. 15300-15306
    • Richard, J.P.1    Melikov, K.2    Brooks, H.3    Prevot, P.4    Lebleu, B.5    Chernomordik, L.V.6
  • 92
    • 0023582912 scopus 로고
    • Acidification of the cytosol inhibits endocytosis from coated pits
    • Sandvig K, Olsnes S, Petersen OW, and van Deurs B (1987) Acidification of the cytosol inhibits endocytosis from coated pits. J Cell Biol 105:679-689.
    • (1987) J Cell Biol , vol.105 , pp. 679-689
    • Sandvig, K.1    Olsnes, S.2    Petersen, O.W.3    Van Deurs, B.4
  • 93
    • 0023024475 scopus 로고
    • Temperature-sensitive steps in the transport of secretory proteins through the Golgi complex in exocrine pancreatic cells
    • Saraste J, Palade GE, and Farquhar MG (1986) Temperature-sensitive steps in the transport of secretory proteins through the Golgi complex in exocrine pancreatic cells. Proc Natl Acad Sci USA 83:6425-6429.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 6425-6429
    • Saraste, J.1    Palade, G.E.2    Farquhar, M.G.3
  • 94
    • 0030957355 scopus 로고    scopus 로고
    • Clathrin-coated vesicle formation and protein sorting: An integrated process
    • Schmid SL (1997) Clathrin-coated vesicle formation and protein sorting: an integrated process. Annu Rev Biochem 66:511-548.
    • (1997) Annu Rev Biochem , vol.66 , pp. 511-548
    • Schmid, S.L.1
  • 95
    • 0027997787 scopus 로고
    • Filipin-sensitive caveolae-mediated transport in endothelium: Reduced transcytosis, scavenger endocytosis and capillary permeability of select macromolecules
    • Schnitzer JE, Oh P, Pinney E, and Allard J (1994) Filipin-sensitive caveolae-mediated transport in endothelium: reduced transcytosis, scavenger endocytosis and capillary permeability of select macromolecules. J Cell Biol 127:1217-1232.
    • (1994) J Cell Biol , vol.127 , pp. 1217-1232
    • Schnitzer, J.E.1    Oh, P.2    Pinney, E.3    Allard, J.4
  • 97
    • 0342265531 scopus 로고    scopus 로고
    • Mechanisms of gene transfer mediated by lipoplexes associated with targeting ligands or pH-sensitive peptides
    • Simoes S, Slepushkin V, Pires P, Gaspar R de Lima MP, and Duzgunes N (1999) Mechanisms of gene transfer mediated by lipoplexes associated with targeting ligands or pH-sensitive peptides. Gene Ther 6:1798-1807.
    • (1999) Gene Ther , vol.6 , pp. 1798-1807
    • Simoes, S.1    Slepushkin, V.2    Pires, P.3    Gaspar, R.4    De Lima, M.P.5    Duzgunes, N.6
  • 102
    • 0028558740 scopus 로고
    • Rapid endocytosis of interleukin 2 receptors when clathrin-coated pit endocytosis is inhibited
    • Subtil A, Hemar A and Dautry-Varsat A (1994) Rapid endocytosis of interleukin 2 receptors when clathrin-coated pit endocytosis is inhibited. J Cell Sci 107 (Pt 12):3461-3468.
    • (1994) J Cell Sci , vol.107 , Issue.12 PART , pp. 3461-3468
    • Subtil, A.1    Hemar, A.2    Dautry-Varsat, A.3
  • 104
    • 0035915018 scopus 로고    scopus 로고
    • Quantitative studies on the nuclear transport of plasmid DNA and gene expression employing nonviral vectors
    • Tachibana R, Harashima H, Shinohara Y, and Kiwada H (2001) Quantitative studies on the nuclear transport of plasmid DNA and gene expression employing nonviral vectors. Adv Drug Deliv Rev 52:219-226.
    • (2001) Adv Drug Deliv Rev , vol.52 , pp. 219-226
    • Tachibana, R.1    Harashima, H.2    Shinohara, Y.3    Kiwada, H.4
  • 105
    • 0032552941 scopus 로고    scopus 로고
    • Intracellular regulation of macromolecules using pH-sensitive liposomes and nuclear localization signal: Qualitative and quantitative evaluation of intracellular trafficking
    • Tachibana R, Harashima H, Shono M, Azumano M, Niwa M, Futaki S, and Kiwada H (1998) Intracellular regulation of macromolecules using pH-sensitive liposomes and nuclear localization signal: qualitative and quantitative evaluation of intracellular trafficking. Biochem Biophys Res Commun 251:538-544.
    • (1998) Biochem Biophys Res Commun , vol.251 , pp. 538-544
    • Tachibana, R.1    Harashima, H.2    Shono, M.3    Azumano, M.4    Niwa, M.5    Futaki, S.6    Kiwada, H.7
  • 106
    • 0035446006 scopus 로고    scopus 로고
    • Clathrin-mediated endocytosis: Membrane factors pull the trigger
    • Takei K and Haucke V (2001) Clathrin-mediated endocytosis: membrane factors pull the trigger. Trends Cell Biol 11:385-391.
    • (2001) Trends Cell Biol , vol.11 , pp. 385-391
    • Takei, K.1    Haucke, V.2
  • 107
    • 0028923349 scopus 로고
    • Tubular membrane invaginations coated by dynamin rings are induced by GTP-γS in nerve terminals
    • Takei K, McPherson PS, Schmid SL, and De Camilli P (1995) Tubular membrane invaginations coated by dynamin rings are induced by GTP-γS in nerve terminals. Nature (Lond) 374:186-190.
    • (1995) Nature (Lond) , vol.374 , pp. 186-190
    • Takei, K.1    McPherson, P.S.2    Schmid, S.L.3    De Camilli, P.4
  • 108
    • 0020635123 scopus 로고
    • Perturbation of vesicular traffic with the carboxylic ionophore monensin
    • Tartakoff AM (1983) Perturbation of vesicular traffic with the carboxylic ionophore monensin. Cell 32:1026-1028.
    • (1983) Cell , vol.32 , pp. 1026-1028
    • Tartakoff, A.M.1
  • 111
    • 3843092828 scopus 로고    scopus 로고
    • Chances and pitfalls of cell penetrating peptides for cellular drug delivery
    • Trehin R and Merkle HP (2004) Chances and pitfalls of cell penetrating peptides for cellular drug delivery. Eur J Pharm Biopharm 58:209-223.
    • (2004) Eur J Pharm Biopharm , vol.58 , pp. 209-223
    • Trehin, R.1    Merkle, H.P.2
  • 112
    • 0035793619 scopus 로고    scopus 로고
    • Internalization of HIV-1 Tat requires cell surface heparan sulfate proteoglycans
    • Tyagi M, Rusnati M, Presta M, and Giacca M (2001) Internalization of HIV-1 Tat requires cell surface heparan sulfate proteoglycans. J Biol Chem 276:3254-3261.
    • (2001) J Biol Chem , vol.276 , pp. 3254-3261
    • Tyagi, M.1    Rusnati, M.2    Presta, M.3    Giacca, M.4
  • 113
    • 0030904245 scopus 로고    scopus 로고
    • A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus
    • Vives E, Brodin P, and Lebleu B (1997) A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus. J Biol Chem 272:16010-16017.
    • (1997) J Biol Chem , vol.272 , pp. 16010-16017
    • Vives, E.1    Brodin, P.2    Lebleu, B.3
  • 114
    • 2342595835 scopus 로고    scopus 로고
    • Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis
    • Wadia JS, Stan RV, and Dowdy SF (2004) Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis. Nat Med 10:310-315.
    • (2004) Nat Med , vol.10 , pp. 310-315
    • Wadia, J.S.1    Stan, R.V.2    Dowdy, S.F.3
  • 115
    • 0026655684 scopus 로고
    • Influenza virus hemagglutinin HA-2 N-terminal fusogenic peptides augment gene transfer by transferrin-polylysine-DNA complexes: Toward a synthetic virus-like gene-transfer vehicle
    • Wagner E, Plank C, Zatloukal K, Cotten M, and Birnstiel ML (1992) Influenza virus hemagglutinin HA-2 N-terminal fusogenic peptides augment gene transfer by transferrin-polylysine-DNA complexes: toward a synthetic virus-like gene-transfer vehicle. Proc Natl Acad Sci USA 89:7934-7938.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 7934-7938
    • Wagner, E.1    Plank, C.2    Zatloukal, K.3    Cotten, M.4    Birnstiel, M.L.5
  • 116
    • 0027520440 scopus 로고
    • Mis-assembly of clathrin lattices on endosomes reveals a regulatory switch for coated pit formation
    • Wang LH, Rothberg KG, and Anderson RG (1993) Mis-assembly of clathrin lattices on endosomes reveals a regulatory switch for coated pit formation. J Cell Biol 123:1107-1117.
    • (1993) J Cell Biol , vol.123 , pp. 1107-1117
    • Wang, L.H.1    Rothberg, K.G.2    Anderson, R.G.3
  • 117
    • 0029912533 scopus 로고    scopus 로고
    • Plasmid DNA is protected against ultrasonic cavitation-induced damage when complexed to cationic liposomes
    • Wasan EK, Reimer DL, and Bally MB (1996) Plasmid DNA is protected against ultrasonic cavitation-induced damage when complexed to cationic liposomes. J Pharm Sci 85:427-433.
    • (1996) J Pharm Sci , vol.85 , pp. 427-433
    • Wasan, E.K.1    Reimer, D.L.2    Bally, M.B.3
  • 119
    • 0028213641 scopus 로고
    • Syndecan 4 heparan sulfate proteoglycan is a selectively enriched and widespread focal adhesion component
    • Woods A and Couchman JR (1994) Syndecan 4 heparan sulfate proteoglycan is a selectively enriched and widespread focal adhesion component. Mol Biol Cell 5:183-192.
    • (1994) Mol Biol Cell , vol.5 , pp. 183-192
    • Woods, A.1    Couchman, J.R.2
  • 120
    • 0029019120 scopus 로고
    • Fusion of cationic liposomes with mammalian cells occurs after endocytosis
    • Wrobel I and Collins D (1995) Fusion of cationic liposomes with mammalian cells occurs after endocytosis. Biochim Biophys Acta 1235:296-304.
    • (1995) Biochim Biophys Acta , vol.1235 , pp. 296-304
    • Wrobel, I.1    Collins, D.2
  • 121
    • 0023212742 scopus 로고
    • Receptor-mediated in vitro gene transformation by a soluble DNA carrier system
    • Wu GY and Wu CH (1987) Receptor-mediated in vitro gene transformation by a soluble DNA carrier system. J Biol Chem 262:4429-4432.
    • (1987) J Biol Chem , vol.262 , pp. 4429-4432
    • Wu, G.Y.1    Wu, C.H.2
  • 122
    • 0029949266 scopus 로고    scopus 로고
    • Mechanism of DNA release from cationic liposome/ DNA complexes used in cell transfection
    • Xu Y and Szoka FC Jr (1996) Mechanism of DNA release from cationic liposome/ DNA complexes used in cell transfection. Biochemistry 35:5616-5623.
    • (1996) Biochemistry , vol.35 , pp. 5616-5623
    • Xu, Y.1    Szoka Jr., F.C.2
  • 125
    • 0035257013 scopus 로고    scopus 로고
    • Rab proteins as membrane organizers
    • Zerial M, and McBride H (2001) Rab proteins as membrane organizers. Nat Rev Mol Cell Biol 2:107-117.
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 107-117
    • Zerial, M.1    McBride, H.2
  • 126
    • 0028097638 scopus 로고
    • DNA transfection mediated by cationic liposomes containing lipopolylysine: Characterization and mechanism of action
    • Zhou X, and Huang L (1994) DNA transfection mediated by cationic liposomes containing lipopolylysine: characterization and mechanism of action. Biochim Biophys Acta 1189:195-203.
    • (1994) Biochim Biophys Acta , vol.1189 , pp. 195-203
    • Zhou, X.1    Huang, L.2
  • 127
    • 0037124051 scopus 로고    scopus 로고
    • Lipoplex-mediated transfection of mammalian cells occurs through the cholesterol-dependent clathrin-mediated pathway of endocytosis
    • Zuhorn IS, Kalicharan R, and Hoekstra D (2002) Lipoplex-mediated transfection of mammalian cells occurs through the cholesterol-dependent clathrin-mediated pathway of endocytosis. J Biol Chem 277:18021-18028.
    • (2002) J Biol Chem , vol.277 , pp. 18021-18028
    • Zuhorn, I.S.1    Kalicharan, R.2    Hoekstra, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.