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Volumn 41, Issue 2, 2000, Pages 189-200

Lysosome membrane permeability: Implications for drug delivery

Author keywords

Drug delivery; Lysosomes; Membrane permeability

Indexed keywords

CONTROLLED DRUG DELIVERY; DIFFUSION; DRUG PRODUCTS; ENZYMES; HYDROGEN BONDS; MACROMOLECULES; METABOLISM; METABOLITES; MOLECULES; SUGAR (SUCROSE);

EID: 0343067073     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-409X(99)00065-4     Document Type: Article
Times cited : (85)

References (36)
  • 1
    • 0343840628 scopus 로고
    • Tissue fractionation studies. 2. The nature of the linkage between acid phosphatase and mitochondria in rat-liver tissue
    • Berthet J., Bethet L., Appelmans F., de Duve C. Tissue fractionation studies. 2. The nature of the linkage between acid phosphatase and mitochondria in rat-liver tissue. Biochem. J. 50:1951;182-189.
    • (1951) Biochem. J. , vol.50 , pp. 182-189
    • Berthet, J.1    Bethet, L.2    Appelmans, F.3    De Duve, C.4
  • 2
    • 77049229661 scopus 로고
    • Tissue fractionation studies. 6. Intracellular distribution patterns of enzymes in rat-liver tissue
    • de Duve C., Pressman B.C., Gianetto R., Wattiaux R., Appelmans F. Tissue fractionation studies. 6. Intracellular distribution patterns of enzymes in rat-liver tissue. Biochem. J. 60:1955;604-617.
    • (1955) Biochem. J. , vol.60 , pp. 604-617
    • De Duve, C.1    Pressman, B.C.2    Gianetto, R.3    Wattiaux, R.4    Appelmans, F.5
  • 3
    • 0003056776 scopus 로고
    • The lysosome in retrospect
    • J.T. Dingle, Fell H.B. Amsterdam: North-Holland
    • de Duve C. The lysosome in retrospect. Dingle J.T., Fell H.B. Lysosomes in Biology and Pathology. Vol. 1:1969;3-40 North-Holland, Amsterdam.
    • (1969) Lysosomes in Biology and Pathology , vol.1 , pp. 3-40
    • De Duve, C.1
  • 6
    • 0030337835 scopus 로고    scopus 로고
    • Acidification of lysosomes and endosomes
    • J.B. Lloyd, Mason R.W. New York: Plenum Press
    • Van Dyke R.W. Acidification of lysosomes and endosomes. Lloyd J.B., Mason R.W. Biology of the Lysosome. 1996;331-360 Plenum Press, New York.
    • (1996) Biology of the Lysosome , pp. 331-360
    • Van Dyke, R.W.1
  • 7
    • 0016322758 scopus 로고
    • The role of surface carbohydrates in the hepatic recognition and transport of circulating glycoproteins
    • Ashwell G., Morell A.G. The role of surface carbohydrates in the hepatic recognition and transport of circulating glycoproteins. Adv. Enzymol. 41:1974;99-128.
    • (1974) Adv. Enzymol. , vol.41 , pp. 99-128
    • Ashwell, G.1    Morell, A.G.2
  • 8
    • 0020467066 scopus 로고
    • Degradation of side-chains of N-(2-hydroxypropyl)methacrylamide copolymers by lysosomal thiol-proteinases
    • Duncan R., Cable H.C., Lloyd J.B., Rejmanova P., Kopecek J. Degradation of side-chains of N-(2-hydroxypropyl)methacrylamide copolymers by lysosomal thiol-proteinases. Biosci. Rep. 2:1982;1041-1046.
    • (1982) Biosci. Rep. , vol.2 , pp. 1041-1046
    • Duncan, R.1    Cable, H.C.2    Lloyd, J.B.3    Rejmanova, P.4    Kopecek, J.5
  • 9
    • 0022002504 scopus 로고
    • Stability in rat plasma and serum of lysosomally degradable oligopeptide sequences in N-(2-hydroxypropyl)methacrylamide copolymers
    • Rejmanova P., Kopecek J., Duncan R., Lloyd J.B. Stability in rat plasma and serum of lysosomally degradable oligopeptide sequences in N-(2-hydroxypropyl)methacrylamide copolymers. Biomaterials. 6:1985;45-48.
    • (1985) Biomaterials , vol.6 , pp. 45-48
    • Rejmanova, P.1    Kopecek, J.2    Duncan, R.3    Lloyd, J.B.4
  • 10
    • 0020682412 scopus 로고
    • Targeting of N-(2-hydroxypropyl)methacrylamide copolymers to liver by incorporation of galactose residues
    • Duncan R., Kopecek J., Rejmanova P., Lloyd J.B. Targeting of N-(2-hydroxypropyl)methacrylamide copolymers to liver by incorporation of galactose residues. Biochim. Biophys. Acta. 755:1983;518-521.
    • (1983) Biochim. Biophys. Acta , vol.755 , pp. 518-521
    • Duncan, R.1    Kopecek, J.2    Rejmanova, P.3    Lloyd, J.B.4
  • 11
    • 0022635574 scopus 로고
    • Fate of N-(2-hydroxypropyl)methacrylamide copolymers with pendent galactosamine residues after intravenous administration to rats
    • Duncan R., Seymour L.C.W., Scarlett L., Lloyd J.B., Rejmanova P., Kopecek J. Fate of N-(2-hydroxypropyl)methacrylamide copolymers with pendent galactosamine residues after intravenous administration to rats. Biochim. Biophys. Acta. 880:1986;62-71.
    • (1986) Biochim. Biophys. Acta , vol.880 , pp. 62-71
    • Duncan, R.1    Seymour, L.C.W.2    Scarlett, L.3    Lloyd, J.B.4    Rejmanova, P.5    Kopecek, J.6
  • 12
    • 0023141221 scopus 로고
    • Anticancer agents coupled to of N-(2-hydroxypropyl)methacrylamide copolymers. I. Evaluation of daunomycin and puromcycin conjugates in vitro
    • Duncan R., Kopeckova-Rejmanova P., Strohalm J., Hume I., Cable H.C., Pohl J., Lloyd J.B., Kopecek J. Anticancer agents coupled to of N-(2-hydroxypropyl)methacrylamide copolymers. I. Evaluation of daunomycin and puromcycin conjugates in vitro. Br. J. Cancer. 55:1987;165-174.
    • (1987) Br. J. Cancer , vol.55 , pp. 165-174
    • Duncan, R.1    Kopeckova-Rejmanova, P.2    Strohalm, J.3    Hume, I.4    Cable, H.C.5    Pohl, J.6    Lloyd, J.B.7    Kopecek, J.8
  • 13
    • 0023829660 scopus 로고
    • Anticancer agents coupled to of N-(2-hydroxypropyl)methacrylamide copolymers. II. Evaluation of daunomycin conjugates in vivo against L1210 leukaemia
    • Duncan R., Kopeckova P., Strohalm J., Hume I., Lloyd J.B., Kopecek J. Anticancer agents coupled to of N-(2-hydroxypropyl)methacrylamide copolymers. II. Evaluation of daunomycin conjugates in vivo against L1210 leukaemia. Br. J. Cancer. 57:1988;147-156.
    • (1988) Br. J. Cancer , vol.57 , pp. 147-156
    • Duncan, R.1    Kopeckova, P.2    Strohalm, J.3    Hume, I.4    Lloyd, J.B.5    Kopecek, J.6
  • 14
    • 0022858683 scopus 로고
    • A new concept for macromolecular therapeutics in cancer chemotherapy: Mechanisms of tumoritropic accumulation of protein and the antitumor agent SMANCS
    • Matsamura Y., Maeda H. A new concept for macromolecular therapeutics in cancer chemotherapy: mechanisms of tumoritropic accumulation of protein and the antitumor agent SMANCS. Cancer Res. 46:1986;6387-6392.
    • (1986) Cancer Res. , vol.46 , pp. 6387-6392
    • Matsamura, Y.1    Maeda, H.2
  • 16
    • 0030338965 scopus 로고    scopus 로고
    • Metabolite efflux and influx across the lysosome membrane
    • J.B. Lloyd, Mason R.W. New York: Plenum Press
    • Lloyd J.B. Metabolite efflux and influx across the lysosome membrane. Lloyd J.B., Mason R.W. Biology of the Lysosome. 1996;361-386 Plenum Press, New York.
    • (1996) Biology of the Lysosome , pp. 361-386
    • Lloyd, J.B.1
  • 17
    • 0014642891 scopus 로고
    • Studies on the permeability of rat liver lysosomes to carbohydrates
    • Lloyd J.B. Studies on the permeability of rat liver lysosomes to carbohydrates. Biochem. J. 115:1969;703-707.
    • (1969) Biochem. J. , vol.115 , pp. 703-707
    • Lloyd, J.B.1
  • 18
    • 0024360386 scopus 로고
    • Passive diffusion of non-electrolytes across the lysosome membrane
    • Iveson G.P., Bird S.J., Lloyd J.B. Passive diffusion of non-electrolytes across the lysosome membrane. Biochem. J. 261:1989;451-456.
    • (1989) Biochem. J. , vol.261 , pp. 451-456
    • Iveson, G.P.1    Bird, S.J.2    Lloyd, J.B.3
  • 20
    • 0014439655 scopus 로고
    • Biological membranes: The physical basis of ion and nonelectrolyte selectivity
    • Diamond J.M., Wright E.M. Biological membranes: the physical basis of ion and nonelectrolyte selectivity. Annu. Rev. Physiol. 31:1969;581-646.
    • (1969) Annu. Rev. Physiol. , vol.31 , pp. 581-646
    • Diamond, J.M.1    Wright, E.M.2
  • 23
    • 0028901997 scopus 로고
    • Organic cation transport by rat liver lysosomes
    • Moseley R.H., Van Dyke R.W. Organic cation transport by rat liver lysosomes. Am. J. Physiol. 268:1995;G480-G486.
    • (1995) Am. J. Physiol. , vol.268
    • Moseley, R.H.1    Van Dyke, R.W.2
  • 25
    • 0028804534 scopus 로고
    • Detection and characterization of a transport system mediating cysteamine entry into human fibroblast lysosomes
    • Pisoni R.L., Park G.Y., Velilla V.Q., Thoene J.G. Detection and characterization of a transport system mediating cysteamine entry into human fibroblast lysosomes. J. Biol. Chem. 270:1995;1179-1184.
    • (1995) J. Biol. Chem. , vol.270 , pp. 1179-1184
    • Pisoni, R.L.1    Park, G.Y.2    Velilla, V.Q.3    Thoene, J.G.4
  • 26
    • 0021860843 scopus 로고
    • Detection and characterization of carrier-mediated cationic amino acid transport in lysosomes of normal and cystinotic human fibroblasts
    • Pisoni R.L., Thoene J.G., Christensen H.N. Detection and characterization of carrier-mediated cationic amino acid transport in lysosomes of normal and cystinotic human fibroblasts. J. Biol. Chem. 260:1985;4791-4798.
    • (1985) J. Biol. Chem. , vol.260 , pp. 4791-4798
    • Pisoni, R.L.1    Thoene, J.G.2    Christensen, H.N.3
  • 27
    • 0014438630 scopus 로고
    • The uptake, storage, and intracellular hydrolysis of carbohydrates by macrophages
    • Cohn Z.A., Ehrenreich B.A. The uptake, storage, and intracellular hydrolysis of carbohydrates by macrophages. J. Exp. Med. 129:1969;201-225.
    • (1969) J. Exp. Med. , vol.129 , pp. 201-225
    • Cohn, Z.A.1    Ehrenreich, B.A.2
  • 28
    • 0014447533 scopus 로고
    • The fate of peptides pinocytosed by macrophages in vitro
    • Ehrenreich B.A., Cohn Z.A. The fate of peptides pinocytosed by macrophages in vitro. J. Exp. Med. 129:1969;227-245.
    • (1969) J. Exp. Med. , vol.129 , pp. 227-245
    • Ehrenreich, B.A.1    Cohn, Z.A.2
  • 29
    • 0343840626 scopus 로고
    • Experimental support for the concept of lysosomal storage disease
    • H.G. Hers, van Hoof F. New York: Academic Press
    • Lloyd J.B. Experimental support for the concept of lysosomal storage disease. Hers H.G., van Hoof F. Lysosomes and Storage Diseases. 1973;173-195 Academic Press, New York.
    • (1973) Lysosomes and Storage Diseases , pp. 173-195
    • Lloyd, J.B.1
  • 30
    • 0019788761 scopus 로고
    • Cytoplasmic vacuolation of mouse peritoneal macrophages and the uptake into lysosomes of weakly basic substances
    • Ohkuma S., Poole B. Cytoplasmic vacuolation of mouse peritoneal macrophages and the uptake into lysosomes of weakly basic substances. J. Cell Biol. 90:1981;656-664.
    • (1981) J. Cell Biol. , vol.90 , pp. 656-664
    • Ohkuma, S.1    Poole, B.2
  • 31
    • 0014909672 scopus 로고
    • The metabolism of amino acids, peptides, and disulfides in lysosomes of fibroblasts cultured from normal individuals and those with cystinosis
    • Schulman J.D., Bradley K.H. The metabolism of amino acids, peptides, and disulfides in lysosomes of fibroblasts cultured from normal individuals and those with cystinosis. J. Exp. Med. 132:1970;1090-1104.
    • (1970) J. Exp. Med. , vol.132 , pp. 1090-1104
    • Schulman, J.D.1    Bradley, K.H.2
  • 32
    • 0019884074 scopus 로고
    • Pinocytic uptake and intracellular degradation of N-(2-hydroxypropyl) methacrylamide copolymers: A potential drug delivery system
    • Duncan R., Rejmanova P., Kopecek J., Lloyd J.B. Pinocytic uptake and intracellular degradation of N-(2-hydroxypropyl) methacrylamide copolymers: a potential drug delivery system. Biochim. Biophys. Acta. 678:1981;143-150.
    • (1981) Biochim. Biophys. Acta , vol.678 , pp. 143-150
    • Duncan, R.1    Rejmanova, P.2    Kopecek, J.3    Lloyd, J.B.4
  • 33
    • 0025974150 scopus 로고
    • Evidence that desferrioxamine cannot enter cells by passive diffusion
    • Lloyd J.B., Cable H.C., Rice-Evans C. Evidence that desferrioxamine cannot enter cells by passive diffusion. Biochem. Pharmacol. 41:1990;1361-1363.
    • (1990) Biochem. Pharmacol. , vol.41 , pp. 1361-1363
    • Lloyd, J.B.1    Cable, H.C.2    Rice-Evans, C.3
  • 34
    • 0033066791 scopus 로고    scopus 로고
    • Cellular uptake and release of two contrasting iron chelators
    • Cable H., Lloyd J.B. Cellular uptake and release of two contrasting iron chelators. J. Pharm. Pharmacol. 51:1999;131-134.
    • (1999) J. Pharm. Pharmacol. , vol.51 , pp. 131-134
    • Cable, H.1    Lloyd, J.B.2
  • 35
    • 0029964866 scopus 로고    scopus 로고
    • Mechanism of oligonucleotide release from cationic liposomes
    • Zelphati O., Szoka F.C. Mechanism of oligonucleotide release from cationic liposomes. Proc. Natl. Acad. Sci. USA. 93:1996;11493-11498.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 11493-11498
    • Zelphati, O.1    Szoka, F.C.2
  • 36
    • 0031782223 scopus 로고    scopus 로고
    • Effects of polyethyleneimine on endocytosis and lysosome stability
    • Klemm A.R., Young D., Lloyd J.B. Effects of polyethyleneimine on endocytosis and lysosome stability. Biochem. Pharmacol. 56:1998;41-46.
    • (1998) Biochem. Pharmacol. , vol.56 , pp. 41-46
    • Klemm, A.R.1    Young, D.2    Lloyd, J.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.