Cellular uptake of arginine-rich peptides: Roles for macropinocytosis and actin rearrangement

Molecular Therapy

Volumn 10, Issue 6, 2004, Pages 1011-1022

  Nakase, Ikuhiko ^a   Niwa, Miki ^a   Takeuchi, Toshihide ^a   Sonomura, Kazuhiro ^a   Kawabata, Noriko ^a   Koike, Yukihiro ^a   Takehashi, Masanori ^a   Tanaka, Seigo ^a   Ueda, Kunihiro ^a   Simpson, Jeremy C ^c   Jones, Arwyn T ^d   Sugiura, Yukio ^a   Futaki, Shiroh ^a,b  

^a KYOTO UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c EMBL Heidelberg ^*  (Germany)

^d CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Actin rearrangement; Arginine rich peptides; Cell permeable peptide; HIV 1 Tat; Internalization; Macropinocytosis; Penetratin; Protein delivery; Protein transduction

Indexed keywords

5 (N ETHYL N ISOPROPYL)AMILORIDE; ACTIN; ARGININE; CARRIER PROTEIN; CHLOROQUINE; CYTOCHALASIN D; F ACTIN; OLIGOPEPTIDE; PEPTIDE DERIVATIVE; WORTMANNIN;

ACTIN POLYMERIZATION; ARTICLE; CELL TRANSPORT; CONTROLLED STUDY; CYTOSKELETON; DRUG UPTAKE; FEMALE; GENE DELIVERY SYSTEM; GENE REARRANGEMENT; HELA CELL; HUMAN; HUMAN CELL; OBSERVATION; PINOCYTOSIS; PROTEIN LOCALIZATION; SENSITIVITY ANALYSIS; STATISTICAL SIGNIFICANCE;

ACTINS; APOPTOSIS; ARGININE; CARRIER PROTEINS; CYTOSOL; HELA CELLS; HUMANS; MICROSCOPY, FLUORESCENCE; OLIGOPEPTIDES; PEPTIDES; PINOCYTOSIS; PROTEIN TRANSPORT;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 10344221003     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ymthe.2004.08.010     Document Type: Article

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