A protein derived from the fusion of TAT peptide and FNK, a Bcl-x L derivative, prevents cochlear hair cell death from aminoglycoside ototoxicity in vivo

Journal of Neuroscience Research

Volumn 85, Issue 7, 2007, Pages 1403-1412

  Kashio, Akinori ^a   Sakamoto, Takashi ^a   Suzukawa, Keigo ^a   Asoh, Sadamitsu ^b   Ohta, Shigeo ^b   Yamasoba, Tatsuya ^a,c  

^a UNIVERSITY OF TOKYO   (Japan)

^b NIPPON MEDICAL SCHOOL   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

Apoptosis; Bcl 2; Cochlear damage; Gene therapy; Mitochondria; PARP

Indexed keywords

AMINOGLYCOSIDE; ETACRYNIC ACID; KANAMYCIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BCL XL; PROTEIN FNK; TRANSACTIVATOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; COCHLEA AQUEDUCT; CONTROLLED STUDY; EVOKED BRAIN STEM AUDITORY RESPONSE; FEMALE; HAIR CELL; IN VIVO CULTURE; NONHUMAN; OTOTOXICITY; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION;

AMINOGLYCOSIDES; ANALYSIS OF VARIANCE; ANIMALS; BCL-X PROTEIN; CELL DEATH; COCHLEA; ETHACRYNIC ACID; EVOKED POTENTIALS, AUDITORY, BRAIN STEM; GENE PRODUCTS, TAT; GUINEA PIGS; HAIR CELLS; HEARING LOSS; IMMUNOHISTOCHEMISTRY; KANAMYCIN; MALE; NEUROPROTECTIVE AGENTS; PEPTIDE FRAGMENTS; RECOMBINANT FUSION PROTEINS;

EID: 34248229659     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.21260     Document Type: Article

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