B cells of HIV-1-infected patients bind virions through CD21-complement interactions and transmit infectious virus to activated T cells

Journal of Experimental Medicine

Volumn 192, Issue 5, 2000, Pages 637-645

  Moir, Susan ^a   Malaspina, Angela ^a   Li, Yuexia ^b,d   Chun, Tae Wook ^a   Lowe, Tomeka ^a   Adelsberger, Joseph ^c   Baseler, Michael ^c   Ehler, Linda A ^a   Liu, Shuying ^a   Davey Jr , Richard T ^a   Mican, Jo Ann M ^a   Fauci, Anthony S ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b ADVANCED BIOSCIENCE LABORATORIES INC   (United States)

^c SAIC FREDERICK INC   (United States)

^d VIRxSYS Corporation   (United States)

Author keywords

B cell; CD21; Complement; HIV 1; Viral reservoir

Indexed keywords

COMPLEMENT COMPONENT C3D RECEPTOR;

ARTICLE; B LYMPHOCYTE; CLINICAL ARTICLE; COMPLEMENT FIXATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOPATHOGENESIS; PRIORITY JOURNAL; RECEPTOR BINDING; T LYMPHOCYTE ACTIVATION; VIRUS ADSORPTION; VIRUS TRANSMISSION;

ACQUIRED IMMUNODEFICIENCY SYNDROME; ANTIBODIES, MONOCLONAL; B-LYMPHOCYTES; CHRONIC DISEASE; COMPLEMENT C3; HIV-1; HUMANS; LYMPHOCYTE ACTIVATION; RECEPTORS, COMPLEMENT 3D; RNA, VIRAL; T-LYMPHOCYTES; VIRION;

EID: 0034605036     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.192.5.637     Document Type: Article

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