APOBEC-mediated editing of viral RNA

Science

Volumn 305, Issue 5684, 2004, Pages 645-

  Bishop, Kate N ^a   Holmes, Rebecca K ^a   Sheehy, Ann M ^a   Malim, Michael H ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 3G; CYTIDINE DEAMINASE; UNCLASSIFIED DRUG; VIF PROTEIN; VIRUS RNA; APOLIPOPROTEIN B MRNA EDITING ENZYME; CEM15 PROTEIN, HUMAN; COMPLEMENTARY DNA; DEAMINASE; PROTEIN; REPRESSOR PROTEIN;

RNA;

ARTICLE; DEAMINATION; HEPATITIS B VIRUS; HEPATITIS DELTA VIRUS; HUMAN IMMUNODEFICIENCY VIRUS; LONG TERMINAL REPEAT; MACROPHAGE; MEASLES VIRUS; NONHUMAN; POLYOMA VIRUS; PRIORITY JOURNAL; RNA EDITING; T LYMPHOCYTE; VIRUS PATHOGENESIS; VIRUS REPLICATION; ANIMAL; CELL LINE; GENETIC TRANSFECTION; GENETIC VARIABILITY; GENETICS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; METABOLISM; MUTATION; POLYMERASE CHAIN REACTION; RAT; REGULATOR GENE;

HEPATITIS B VIRUS; HEPATITIS DELTA VIRUS; HUMAN IMMUNODEFICIENCY VIRUS; MEASLES VIRUS; POLYOMAVIRUS;

ANIMALS; CELL LINE; CYTIDINE DEAMINASE; DNA, COMPLEMENTARY; GENES, NEF; HIV LONG TERMINAL REPEAT; HIV-1; HUMANS; MUTATION; NUCLEOSIDE DEAMINASES; POLYMERASE CHAIN REACTION; PROTEINS; RATS; REPRESSOR PROTEINS; RNA EDITING; RNA, VIRAL; TRANSFECTION; VARIATION (GENETICS);

EID: 3442876111     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1100658     Document Type: Article

References (9)

1. B. L. Bass, Annu. Rev. Biochem. 71, 817 (2002).
2. X. Yu et al., Science 302, 1056 (2003).
3. A. Jarmuz, et al., Genomics 79, 285 (2002).
4. Materials and methods are available as supporting material on Science Online.
5. K. N. Bishop et al., Carr. Biol., in press; published online 24 June 2004 (10.1016/50960982204004683).
6. S. Anant, N. O. Davidson, Trends Mol. Med. 9, 147 (2003).
7. R. C. Beale et al., J. Mol. Biol. 337, 585 (2004).
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9. Supported by the U.K. Medical Research Council, the Biotechnology and Biological Sciences Research Council, the Royal Society (A.M.5.), and the Elizabeth Glaser Pediatric AIDS Foundation (M.H.M.).