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Volumn 109, Issue 8, 2007, Pages 3351-3359

HIV inhibits CD4+ T-cell proliferation by inducing indoleamine 2,3-dioxygenase in plasmacytoid dendritic cells

Author keywords

[No Author keywords available]

Indexed keywords

1 METHYL TRYPTOPHAN; CD28 ANTIGEN; CD3 ANTIBODY; CD4 ANTIGEN; GLYCOPROTEIN GP 120; INDOLEAMINE 2,3 DIOXYGENASE; INTERFERON; MESSENGER RNA; PHYTOHEMAGGLUTININ; UNCLASSIFIED DRUG;

EID: 34147115208     PISSN: 00064971     EISSN: 00064971     Source Type: Journal    
DOI: 10.1182/blood-2006-07-034785     Document Type: Article
Times cited : (246)

References (64)
  • 1
    • 0025433391 scopus 로고
    • Immunology of the human immunodeficiency virus infection
    • Dickmeiss E. Immunology of the human immunodeficiency virus infection. Tokai J Exp Clin Med. 1990;15:263-267.
    • (1990) Tokai J Exp Clin Med , vol.15 , pp. 263-267
    • Dickmeiss, E.1
  • 2
    • 0033569187 scopus 로고    scopus 로고
    • Immunologic and virologic studies in long-term nonprogressors with HIV-1 infection
    • Mendila M, Heiken H, Becker S, et al. Immunologic and virologic studies in long-term nonprogressors with HIV-1 infection. Eur J Med Res. 1999;4:417-424.
    • (1999) Eur J Med Res , vol.4 , pp. 417-424
    • Mendila, M.1    Heiken, H.2    Becker, S.3
  • 3
    • 0029620550 scopus 로고
    • The value of the lymphocyte proliferation test with phytohemagglutinin in the immune evaluation of Brazilian HIV-infected patients
    • Casseb JS, Benard G, Saito R, et al. The value of the lymphocyte proliferation test with phytohemagglutinin in the immune evaluation of Brazilian HIV-infected patients. J Investig Allergol Clin Immunol. 1995;5:347-349.
    • (1995) J Investig Allergol Clin Immunol , vol.5 , pp. 347-349
    • Casseb, J.S.1    Benard, G.2    Saito, R.3
  • 4
    • 0027259137 scopus 로고
    • Lymphocyte activation in HIV-1 infection, I: Predominant proliferative defects among CD45R0+ cells of the CD4 and CD8 lineages
    • Janossy G, Borthwick N, Lomnitzer R, et al. Lymphocyte activation in HIV-1 infection, I: predominant proliferative defects among CD45R0+ cells of the CD4 and CD8 lineages. Aids. 1993;7:613-624.
    • (1993) Aids , vol.7 , pp. 613-624
    • Janossy, G.1    Borthwick, N.2    Lomnitzer, R.3
  • 5
    • 0025224564 scopus 로고
    • HIV inhibits the early steps of lymphocyte activation, including initiation of inositol phospholipid metabolism
    • Hofmann B, Nishanian P, Baldwin RL, Insixiengmay P, Nel A, Fahey JL. HIV inhibits the early steps of lymphocyte activation, including initiation of inositol phospholipid metabolism. J Immunol. 1990;145:3699-3705.
    • (1990) J Immunol , vol.145 , pp. 3699-3705
    • Hofmann, B.1    Nishanian, P.2    Baldwin, R.L.3    Insixiengmay, P.4    Nel, A.5    Fahey, J.L.6
  • 6
    • 0036887186 scopus 로고    scopus 로고
    • Backgrounder: Recognizing and diagnosing primary HIV infection
    • Rosenberg E. Backgrounder: recognizing and diagnosing primary HIV infection. Res Initiat Treat Action. 2002;7:5-10.
    • (2002) Res Initiat Treat Action , vol.7 , pp. 5-10
    • Rosenberg, E.1
  • 7
    • 0025214355 scopus 로고
    • Lymphocyte proliferative responses to soluble and liposome-conjugated envelope peptides of HIV-1
    • Krowka J, Stites D, Debs R, et al. Lymphocyte proliferative responses to soluble and liposome-conjugated envelope peptides of HIV-1. J Immunol. 1990;144:2535-2540.
    • (1990) J Immunol , vol.144 , pp. 2535-2540
    • Krowka, J.1    Stites, D.2    Debs, R.3
  • 8
    • 0023233946 scopus 로고
    • Characteristics of the specific cell-mediated immune response in human immunodeficiency virus infection
    • Wahren B, Morfeldt-Mansson L, Biberfeld G, et al. Characteristics of the specific cell-mediated immune response in human immunodeficiency virus infection. J Virol. 1987;61:2017-2023.
    • (1987) J Virol , vol.61 , pp. 2017-2023
    • Wahren, B.1    Morfeldt-Mansson, L.2    Biberfeld, G.3
  • 9
    • 0024786954 scopus 로고
    • Detection of three distinct patterns of T helper cell dysfunction in asymptomatic, human immunodeficiency virus-seropositive patients: Independence of CD4+ cell numbers and clinical staging
    • Clerici M, Stocks NI, Zajac RA, et al. Detection of three distinct patterns of T helper cell dysfunction in asymptomatic, human immunodeficiency virus-seropositive patients: independence of CD4+ cell numbers and clinical staging. J Clin Invest. 1989;84:1892-1899.
    • (1989) J Clin Invest , vol.84 , pp. 1892-1899
    • Clerici, M.1    Stocks, N.I.2    Zajac, R.A.3
  • 10
    • 0029031796 scopus 로고
    • In vitro T cell function, delayed-type hypersensitivity skin testing, and CD4+ T cell subset phenotyping independently predict survival time in patients infected with human immunodeficiency virus
    • Dolan MJ, Clerici M, Blatt SP, et al. In vitro T cell function, delayed-type hypersensitivity skin testing, and CD4+ T cell subset phenotyping independently predict survival time in patients infected with human immunodeficiency virus. J Infect Dis. 1995;172:79-87.
    • (1995) J Infect Dis , vol.172 , pp. 79-87
    • Dolan, M.J.1    Clerici, M.2    Blatt, S.P.3
  • 11
    • 5044220930 scopus 로고    scopus 로고
    • IDO expression by dendritic cells: Tolerance and tryptophan catabolism
    • Mellor AL, Munn DH. IDO expression by dendritic cells: tolerance and tryptophan catabolism. Nat Rev Immunol. 2004;4:762-774.
    • (2004) Nat Rev Immunol , vol.4 , pp. 762-774
    • Mellor, A.L.1    Munn, D.H.2
  • 12
    • 0036341332 scopus 로고    scopus 로고
    • Effect of indoleamine 2,3-dioxygenase on induction of experimental autoimmune encephalomyelitis
    • Sakurai K, Zou JP, Tschetter JR, Ward JM, Shearer GM. Effect of indoleamine 2,3-dioxygenase on induction of experimental autoimmune encephalomyelitis. J Neuroimmunol. 2002;129:186-196.
    • (2002) J Neuroimmunol , vol.129 , pp. 186-196
    • Sakurai, K.1    Zou, J.P.2    Tschetter, J.R.3    Ward, J.M.4    Shearer, G.M.5
  • 13
    • 0037815119 scopus 로고    scopus 로고
    • A defect in tryptophan catabolism impairs tolerance in nonobese diabetic mice
    • Grohmann U, Fallarino F, Bianchi R, et al. A defect in tryptophan catabolism impairs tolerance in nonobese diabetic mice. J Exp Med. 2003;198:153-160.
    • (2003) J Exp Med , vol.198 , pp. 153-160
    • Grohmann, U.1    Fallarino, F.2    Bianchi, R.3
  • 14
    • 0037056234 scopus 로고    scopus 로고
    • Indoleamine 2,3-dioxygenase contributes to tumor cell evasion of T cell-mediated rejection
    • Friberg M, Jennings R, Alsarraj M, et al. Indoleamine 2,3-dioxygenase contributes to tumor cell evasion of T cell-mediated rejection. Int J Cancer. 2002;101:151-155.
    • (2002) Int J Cancer , vol.101 , pp. 151-155
    • Friberg, M.1    Jennings, R.2    Alsarraj, M.3
  • 15
    • 0033990826 scopus 로고    scopus 로고
    • Human placental indoleamine 2,3-dioxygenase: Cellular localization and characterization of an enzyme preventing fetal rejection
    • Kudo Y, Boyd CA. Human placental indoleamine 2,3-dioxygenase: cellular localization and characterization of an enzyme preventing fetal rejection. Biochim Biophys Acta. 2000;1500:119-124.
    • (2000) Biochim Biophys Acta , vol.1500 , pp. 119-124
    • Kudo, Y.1    Boyd, C.A.2
  • 16
    • 0032555614 scopus 로고    scopus 로고
    • Prevention of allogeneic fetal rejection by tryptophan catabolism
    • Munn DH, Zhou M, Attwood JT, et al. Prevention of allogeneic fetal rejection by tryptophan catabolism. Science. 1998;281:1191-1193.
    • (1998) Science , vol.281 , pp. 1191-1193
    • Munn, D.H.1    Zhou, M.2    Attwood, J.T.3
  • 17
    • 19344377474 scopus 로고    scopus 로고
    • GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase
    • Munn DH, Sharma MD, Baban B, et al. GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase. Immunity. 2005;22:633-642.
    • (2005) Immunity , vol.22 , pp. 633-642
    • Munn, D.H.1    Sharma, M.D.2    Baban, B.3
  • 18
    • 0025673813 scopus 로고
    • Immune activation and decreased tryptophan in patients with HIV-1 infection
    • Fuchs D, Forsman A, Hagberg L, et al. Immune activation and decreased tryptophan in patients with HIV-1 infection. J Interferon Res. 1990;10:599-603.
    • (1990) J Interferon Res , vol.10 , pp. 599-603
    • Fuchs, D.1    Forsman, A.2    Hagberg, L.3
  • 19
    • 0141533178 scopus 로고    scopus 로고
    • Tryptophan depletion and HIV infection: A metabolic link to pathogenesis
    • Murray MF. Tryptophan depletion and HIV infection: a metabolic link to pathogenesis. Lancet Infect Dis. 2003;3:644-652.
    • (2003) Lancet Infect Dis , vol.3 , pp. 644-652
    • Murray, M.F.1
  • 20
    • 0033931906 scopus 로고    scopus 로고
    • Induction of indoleamine 2,3-dioxygenase in primary human macrophages by HIV-1
    • Grant RS, Naif H, Thuruthyil SJ, et al. Induction of indoleamine 2,3-dioxygenase in primary human macrophages by HIV-1. Redox Rep. 2000;5:105-107.
    • (2000) Redox Rep , vol.5 , pp. 105-107
    • Grant, R.S.1    Naif, H.2    Thuruthyil, S.J.3
  • 21
    • 0031900585 scopus 로고    scopus 로고
    • Serum kynurenine-totryptophan ratio increases with progressive disease in HIV-infected patients
    • Huengsberg M, Winer JB, Gompels M, Round R, Ross J, Shahmanesh M. Serum kynurenine-totryptophan ratio increases with progressive disease in HIV-infected patients. Clin Chem. 1998;44:858-862.
    • (1998) Clin Chem , vol.44 , pp. 858-862
    • Huengsberg, M.1    Winer, J.B.2    Gompels, M.3    Round, R.4    Ross, J.5    Shahmanesh, M.6
  • 22
    • 15844427653 scopus 로고    scopus 로고
    • Involvement of quinolinic acid in AIDS dementia complex
    • Guillemin GJ, Kerr SJ, Brew BJ. Involvement of quinolinic acid in AIDS dementia complex. Neurotox Res. 2005;7:103-123.
    • (2005) Neurotox Res , vol.7 , pp. 103-123
    • Guillemin, G.J.1    Kerr, S.J.2    Brew, B.J.3
  • 23
    • 0031468305 scopus 로고    scopus 로고
    • Kynurenine pathway inhibition reduces neurotoxicity of HIV-1-infected macrophages
    • Kerr SJ, Armati PJ, Pemberton LA, Smythe G, Tattam B, Brew BJ. Kynurenine pathway inhibition reduces neurotoxicity of HIV-1-infected macrophages. Neurology. 1997;49:1671-1681.
    • (1997) Neurology , vol.49 , pp. 1671-1681
    • Kerr, S.J.1    Armati, P.J.2    Pemberton, L.A.3    Smythe, G.4    Tattam, B.5    Brew, B.J.6
  • 24
    • 27144489077 scopus 로고    scopus 로고
    • Inhibition of indoleamine 2,3-dioxygenase (IDO) enhances elimination of virus-infected macrophages in an animal model of HIV-1 encephalitis
    • Potula R, Poluektova L, Knipe B, et al. Inhibition of indoleamine 2,3-dioxygenase (IDO) enhances elimination of virus-infected macrophages in an animal model of HIV-1 encephalitis. Blood. 2005;106:2382-2390.
    • (2005) Blood , vol.106 , pp. 2382-2390
    • Potula, R.1    Poluektova, L.2    Knipe, B.3
  • 25
    • 17444407451 scopus 로고    scopus 로고
    • The prevalence of regulatory T cells in lymphoid tissue is correlated with viral load in HIV-infected patients
    • Andersson J, Boasso A, Nilsson J, et al. The prevalence of regulatory T cells in lymphoid tissue is correlated with viral load in HIV-infected patients. J Immunol. 2005;174:3143-3147.
    • (2005) J Immunol , vol.174 , pp. 3143-3147
    • Andersson, J.1    Boasso, A.2    Nilsson, J.3
  • 26
    • 33750310898 scopus 로고    scopus 로고
    • Nilsson J, Boasso A, Velilla PA, et al. HIV-1-driven regulatory T-cell accumulation in lymphoid tissues is associated with disease progression in HIV/AIDS. Blood. Prepublished on August 10, 2006, as DOI 10.1182/blood-2006-05- 021576. (Now available as Blood. 2006;108:3808-3817.)
    • Nilsson J, Boasso A, Velilla PA, et al. HIV-1-driven regulatory T-cell accumulation in lymphoid tissues is associated with disease progression in HIV/AIDS. Blood. Prepublished on August 10, 2006, as DOI 10.1182/blood-2006-05- 021576. (Now available as Blood. 2006;108:3808-3817.)
  • 27
    • 33144476838 scopus 로고    scopus 로고
    • Premature induction of an immunosuppressive regulatory T cell response during acute simian immunodeficiency virus infection
    • Estes JD, Li Q, Reynolds MR, et al. Premature induction of an immunosuppressive regulatory T cell response during acute simian immunodeficiency virus infection. J Infect Dis. 2006;193:703-712.
    • (2006) J Infect Dis , vol.193 , pp. 703-712
    • Estes, J.D.1    Li, Q.2    Reynolds, M.R.3
  • 28
    • 0031694872 scopus 로고    scopus 로고
    • Inactivation of human immunodeficiency virus type 1 infectivity with preservation of conformational and functional integrity of virion surface proteins
    • Rossio JL, Esser MT, Suryanarayana K, et al. Inactivation of human immunodeficiency virus type 1 infectivity with preservation of conformational and functional integrity of virion surface proteins. J Virol. 1998;72:7992-8001.
    • (1998) J Virol , vol.72 , pp. 7992-8001
    • Rossio, J.L.1    Esser, M.T.2    Suryanarayana, K.3
  • 29
    • 0031761965 scopus 로고    scopus 로고
    • Chemical inactivation of retroviral infectivity by targeting nucleocapsid protein zinc fingers: A candidate SIV vaccine
    • Arthur LO, Bess JW Jr, Chertova EN, et al. Chemical inactivation of retroviral infectivity by targeting nucleocapsid protein zinc fingers: a candidate SIV vaccine. AIDS Res Hum Retroviruses. 1998;14(suppl 3):S311-S319.
    • (1998) AIDS Res Hum Retroviruses , vol.14 , Issue.SUPPL. 3
    • Arthur, L.O.1    Bess Jr, J.W.2    Chertova, E.N.3
  • 30
    • 0037404789 scopus 로고    scopus 로고
    • Sites, mechanism of action and lack of reversibility of primate lentivirus inactivation by preferential covalent modification of virion internal proteins
    • Chertova E, Crise BJ, Morcock DR, Bess JW Jr, Henderson LE, Lifson JD. Sites, mechanism of action and lack of reversibility of primate lentivirus inactivation by preferential covalent modification of virion internal proteins. Curr Mol Med. 2003;3:265-272.
    • (2003) Curr Mol Med , vol.3 , pp. 265-272
    • Chertova, E.1    Crise, B.J.2    Morcock, D.R.3    Bess Jr, J.W.4    Henderson, L.E.5    Lifson, J.D.6
  • 31
    • 0031592573 scopus 로고    scopus 로고
    • Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations
    • Bess JW Jr, Gorelick RJ, Bosche WJ, Henderson LE, Arthur LO. Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations. Virology. 1997;230:134-144.
    • (1997) Virology , vol.230 , pp. 134-144
    • Bess Jr, J.W.1    Gorelick, R.J.2    Bosche, W.J.3    Henderson, L.E.4    Arthur, L.O.5
  • 32
    • 13044249145 scopus 로고    scopus 로고
    • Postexposure immunoprophylaxis of primary isolates by an antibody to HIV receptor complex
    • Wang CY, Sawyer LS, Murthy KK, et al. Postexposure immunoprophylaxis of primary isolates by an antibody to HIV receptor complex. Proc Natl Acad Sci U S A. 1999;96:10367-10372.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 10367-10372
    • Wang, C.Y.1    Sawyer, L.S.2    Murthy, K.K.3
  • 33
    • 0031451315 scopus 로고    scopus 로고
    • Simultaneous measurement of serum tryptophan and kynurenine by HPLC
    • Widner B, Werner ER, Schennach H, Wachter H, Fuchs D. Simultaneous measurement of serum tryptophan and kynurenine by HPLC. Clin Chem. 1997;43:2424-2426.
    • (1997) Clin Chem , vol.43 , pp. 2424-2426
    • Widner, B.1    Werner, E.R.2    Schennach, H.3    Wachter, H.4    Fuchs, D.5
  • 34
    • 0037090313 scopus 로고    scopus 로고
    • Cells expressing indoleamine 2,3-dioxygenase inhibit T cell responses
    • Mellor AL, Keskin DB, Johnson T, Chandler P, Munn DH. Cells expressing indoleamine 2,3-dioxygenase inhibit T cell responses. J Immunol. 2002;168:3771-3776.
    • (2002) J Immunol , vol.168 , pp. 3771-3776
    • Mellor, A.L.1    Keskin, D.B.2    Johnson, T.3    Chandler, P.4    Munn, D.H.5
  • 35
    • 27144552597 scopus 로고    scopus 로고
    • Cutting edge: CpG oligonucleotides induce splenic CD19+ dendritic cells to acquire potent indoleamine 2,3-dioxygenase-dependent T cell regulatory functions via IFN type 1 signaling
    • Mellor AL, Baban B, Chandler PR, Manlapat A, Kahler DJ, Munn DH. Cutting edge: CpG oligonucleotides induce splenic CD19+ dendritic cells to acquire potent indoleamine 2,3-dioxygenase-dependent T cell regulatory functions via IFN type 1 signaling. J Immunol. 2005;175:5601-5605.
    • (2005) J Immunol , vol.175 , pp. 5601-5605
    • Mellor, A.L.1    Baban, B.2    Chandler, P.R.3    Manlapat, A.4    Kahler, D.J.5    Munn, D.H.6
  • 36
    • 0036852170 scopus 로고    scopus 로고
    • CTLA-4-Ig regulates tryptophan catabolism in vivo
    • Grohmann U, Orabona C, Fallarino F, et al. CTLA-4-Ig regulates tryptophan catabolism in vivo. Nat Immunol. 2002;3:1097-1101.
    • (2002) Nat Immunol , vol.3 , pp. 1097-1101
    • Grohmann, U.1    Orabona, C.2    Fallarino, F.3
  • 37
    • 13544271675 scopus 로고    scopus 로고
    • Regulation of indoleamine 2,3-dioxygenase and tryptophanyl-tRNA-synthetase by CTLA-4-Fc in human CD4+ T cells
    • Boasso A, Herbeuval JP, Hardy AW, Winkler C, Shearer GM. Regulation of indoleamine 2,3-dioxygenase and tryptophanyl-tRNA-synthetase by CTLA-4-Fc in human CD4+ T cells. Blood. 2005;105:1574-1581.
    • (2005) Blood , vol.105 , pp. 1574-1581
    • Boasso, A.1    Herbeuval, J.P.2    Hardy, A.W.3    Winkler, C.4    Shearer, G.M.5
  • 38
    • 27744494470 scopus 로고    scopus 로고
    • Ligand and cytokine dependence of the immunosuppressive pathway of tryptophan catabolism in plasmacytoid dendritic cells
    • Fallarino F, Orabona C, Vacca C, et al. Ligand and cytokine dependence of the immunosuppressive pathway of tryptophan catabolism in plasmacytoid dendritic cells. Int Immunol. 2005;17:1429-1438.
    • (2005) Int Immunol , vol.17 , pp. 1429-1438
    • Fallarino, F.1    Orabona, C.2    Vacca, C.3
  • 39
    • 4043092238 scopus 로고    scopus 로고
    • Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes
    • Munn DH, Sharma MD, Hou D, et al. Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes. J Clin Invest. 2004;114:280-290.
    • (2004) J Clin Invest , vol.114 , pp. 280-290
    • Munn, D.H.1    Sharma, M.D.2    Hou, D.3
  • 40
    • 25444490409 scopus 로고    scopus 로고
    • Regulation of TNF-related apoptosis-inducing ligand on primary CD4+ T cells by HIV-1: Role of type I IFN-producing plasmacytoid dendritic cells
    • Herbeuval JP, Hardy AW, Boasso A, et al. Regulation of TNF-related apoptosis-inducing ligand on primary CD4+ T cells by HIV-1: role of type I IFN-producing plasmacytoid dendritic cells. Proc Natl Acad Sci U S A. 2005;102:13974-13979.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 13974-13979
    • Herbeuval, J.P.1    Hardy, A.W.2    Boasso, A.3
  • 41
    • 27744560468 scopus 로고    scopus 로고
    • CD4+ T-cell death induced by infectious and noninfectious HIV-1: Role of type 1 interferon-dependent, TRAIL/DR5-mediated apoptosis
    • Herbeuval JP, Grivel JC, Boasso A, et al. CD4+ T-cell death induced by infectious and noninfectious HIV-1: role of type 1 interferon-dependent, TRAIL/DR5-mediated apoptosis. Blood. 2005;106:3524-3531.
    • (2005) Blood , vol.106 , pp. 3524-3531
    • Herbeuval, J.P.1    Grivel, J.C.2    Boasso, A.3
  • 42
    • 0027289072 scopus 로고
    • The human gene encoding tryptophanyl-tRNA synthetase: Interferon-response elements and exon-intron organization
    • Frolova LY, Grigorieva AY, Sudomoina MA, Kisselev LL. The human gene encoding tryptophanyl-tRNA synthetase: interferon-response elements and exon-intron organization. Gene. 1993;128:237-245.
    • (1993) Gene , vol.128 , pp. 237-245
    • Frolova, L.Y.1    Grigorieva, A.Y.2    Sudomoina, M.A.3    Kisselev, L.L.4
  • 43
    • 0036750583 scopus 로고    scopus 로고
    • Effective antiretroviral therapy reduces degradation of tryptophan in patients with HIV-1 infection
    • Zangerle R, Widner B, Quirchmair G, Neurauter G, Sarcletti M, Fuchs D. Effective antiretroviral therapy reduces degradation of tryptophan in patients with HIV-1 infection. Clin Immunol. 2002;104:242-247.
    • (2002) Clin Immunol , vol.104 , pp. 242-247
    • Zangerle, R.1    Widner, B.2    Quirchmair, G.3    Neurauter, G.4    Sarcletti, M.5    Fuchs, D.6
  • 44
    • 0023912832 scopus 로고
    • Tryptophan degradation in patients infected by human immunodeficiency virus
    • Werner ER, Fuchs D, Hausen A, et al. Tryptophan degradation in patients infected by human immunodeficiency virus. Biol Chem Hoppe Seyler. 1988;369:337-340.
    • (1988) Biol Chem Hoppe Seyler , vol.369 , pp. 337-340
    • Werner, E.R.1    Fuchs, D.2    Hausen, A.3
  • 45
    • 0035885920 scopus 로고    scopus 로고
    • Dressed to kill? a review of why antiviral CD8 T lymphocytes fail to prevent progressive immunodeficiency in HIV-1 infection
    • Lieberman J, Shankar P, Manjunath N, Andersson J. Dressed to kill? a review of why antiviral CD8 T lymphocytes fail to prevent progressive immunodeficiency in HIV-1 infection. Blood. 2001;98:1667-1677.
    • (2001) Blood , vol.98 , pp. 1667-1677
    • Lieberman, J.1    Shankar, P.2    Manjunath, N.3    Andersson, J.4
  • 46
    • 0033852737 scopus 로고    scopus 로고
    • Human immunodeficiency virus-specific circulating CD8 T lymphocytes have down-modulated CD3zeta and CD28, key signaling molecules for T-cell activation
    • Trimble LA, Shankar P, Patterson M, Daily JP, Lieberman J. Human immunodeficiency virus-specific circulating CD8 T lymphocytes have down-modulated CD3zeta and CD28, key signaling molecules for T-cell activation. J Virol. 2000;74:7320-7330.
    • (2000) J Virol , vol.74 , pp. 7320-7330
    • Trimble, L.A.1    Shankar, P.2    Patterson, M.3    Daily, J.P.4    Lieberman, J.5
  • 47
    • 33749338938 scopus 로고    scopus 로고
    • PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection
    • Petrovas C, Casazza JP, Brenchley JM, et al. PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection. J Exp Med. 2006;203:2281-2292.
    • (2006) J Exp Med , vol.203 , pp. 2281-2292
    • Petrovas, C.1    Casazza, J.P.2    Brenchley, J.M.3
  • 48
    • 33748947326 scopus 로고    scopus 로고
    • PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression
    • Day CL, Kaufmann DE, Kiepiela P, et al. PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression. Nature. 2006;443:350-354.
    • (2006) Nature , vol.443 , pp. 350-354
    • Day, C.L.1    Kaufmann, D.E.2    Kiepiela, P.3
  • 49
    • 33749009709 scopus 로고    scopus 로고
    • Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction
    • Trautmann L, Janbazian L, Chomont N, et al. Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction. Nat Med. 2006;12:1198-1202.
    • (2006) Nat Med , vol.12 , pp. 1198-1202
    • Trautmann, L.1    Janbazian, L.2    Chomont, N.3
  • 50
    • 32944468867 scopus 로고    scopus 로고
    • Differential effects of the tryptophan metabolite 3-hydroxyanthranilic acid on the proliferation of human CD8+ T cells induced by TCR triggering or homeostatic cytokines
    • Weber WP, Feder-Mengus C, Chiarugi A, et al. Differential effects of the tryptophan metabolite 3-hydroxyanthranilic acid on the proliferation of human CD8+ T cells induced by TCR triggering or homeostatic cytokines. Eur J Immunol. 2006;36:296-304.
    • (2006) Eur J Immunol , vol.36 , pp. 296-304
    • Weber, W.P.1    Feder-Mengus, C.2    Chiarugi, A.3
  • 51
    • 33646893538 scopus 로고    scopus 로고
    • The combined effects of tryptophan starvation and tryptophan catabolites down-regulate T cell receptor {zeta}-chain and induce a regulatory phenotype in naive T cells
    • Fallarino F, Grohmann U, You S, et al. The combined effects of tryptophan starvation and tryptophan catabolites down-regulate T cell receptor {zeta}-chain and induce a regulatory phenotype in naive T cells. J Immunol. 2006;176:6752-6761.
    • (2006) J Immunol , vol.176 , pp. 6752-6761
    • Fallarino, F.1    Grohmann, U.2    You, S.3
  • 52
    • 33344459240 scopus 로고    scopus 로고
    • Failure of HIV-exposed CD4+ T cells to activate dendritic cells is reversed by restoration of CD40/CD154 interactions
    • Zhang R, Lifson JD, Chougnet C. Failure of HIV-exposed CD4+ T cells to activate dendritic cells is reversed by restoration of CD40/CD154 interactions. Blood. 2006;107:1989-1995.
    • (2006) Blood , vol.107 , pp. 1989-1995
    • Zhang, R.1    Lifson, J.D.2    Chougnet, C.3
  • 53
    • 33646468496 scopus 로고    scopus 로고
    • Differential expression of IFN-alpha and TRAIL/DR5 in lymphoid tissue of progressor versus nonprogressor HIV-1-infected patients
    • Herbeuval JP, Nilsson J, Boasso A, et al. Differential expression of IFN-alpha and TRAIL/DR5 in lymphoid tissue of progressor versus nonprogressor HIV-1-infected patients. Proc Natl Acad Sci U S A. 2006;103:7000-7005.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 7000-7005
    • Herbeuval, J.P.1    Nilsson, J.2    Boasso, A.3
  • 54
    • 15244358107 scopus 로고    scopus 로고
    • TNF-related apoptosis-inducing ligand (TRAIL) in HIV-1-infected patients and its in vitro production by antigen-presenting cells
    • Herbeuval JP, Boasso A, Grivel JC, et al. TNF-related apoptosis-inducing ligand (TRAIL) in HIV-1-infected patients and its in vitro production by antigen-presenting cells. Blood. 2005;105:2458-2464.
    • (2005) Blood , vol.105 , pp. 2458-2464
    • Herbeuval, J.P.1    Boasso, A.2    Grivel, J.C.3
  • 55
    • 2942661334 scopus 로고    scopus 로고
    • Noninfectious X4 but not R5 human immunodeficiency virus type 1 virions inhibit humoral immune responses in human lymphoid tissue ex vivo
    • Fitzgerald W, Sylwester AW, Grivel JC, Lifson JD, Margolis LB. Noninfectious X4 but not R5 human immunodeficiency virus type 1 virions inhibit humoral immune responses in human lymphoid tissue ex vivo. J Virol. 2004;78:7061-7068.
    • (2004) J Virol , vol.78 , pp. 7061-7068
    • Fitzgerald, W.1    Sylwester, A.W.2    Grivel, J.C.3    Lifson, J.D.4    Margolis, L.B.5
  • 56
    • 2342648904 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 activates plasmacytoid dendritic cells and concomitantly induces the bystander maturation of myeloid dendritic cells
    • Fonteneau JF, Larsson M, Beignon AS, et al. Human immunodeficiency virus type 1 activates plasmacytoid dendritic cells and concomitantly induces the bystander maturation of myeloid dendritic cells. J Virol. 2004;78:5223-5232.
    • (2004) J Virol , vol.78 , pp. 5223-5232
    • Fonteneau, J.F.1    Larsson, M.2    Beignon, A.S.3
  • 57
    • 33845236614 scopus 로고    scopus 로고
    • Hryniewicz A, Boasso A, Edghill-Smith Y, et al. CTLA-4 blockade decreases TGF-β-, IDO, and viral RNA expression in tissues of SIVmac251-infected macaques. Prepublished on August 8, 2006, as DOI 10.1182/blood-2006-04-010637. (Now available as Blood. 2006;108:3834-3842.)
    • Hryniewicz A, Boasso A, Edghill-Smith Y, et al. CTLA-4 blockade decreases TGF-β-, IDO, and viral RNA expression in tissues of SIVmac251-infected macaques. Prepublished on August 8, 2006, as DOI 10.1182/blood-2006-04-010637. (Now available as Blood. 2006;108:3834-3842.)
  • 58
    • 26444489716 scopus 로고    scopus 로고
    • A minor population of splenic dendritic cells expressing CD19 mediates IDO-dependent T cell suppression via type I IFN signaling following B7 ligation
    • Baban B, Hansen AM, Chandler PR, et al. A minor population of splenic dendritic cells expressing CD19 mediates IDO-dependent T cell suppression via type I IFN signaling following B7 ligation. Int Immunol. 2005;17:909-919.
    • (2005) Int Immunol , vol.17 , pp. 909-919
    • Baban, B.1    Hansen, A.M.2    Chandler, P.R.3
  • 59
    • 30944452875 scopus 로고    scopus 로고
    • Variations in plasmacytoid dendritic cell (PDC) and myeloid dendritic cell (MDC) levels in HIV-infected subjects on and off antiretroviral therapy
    • Schmidt B, Fujimura SH, Martin JN, Levy JA. Variations in plasmacytoid dendritic cell (PDC) and myeloid dendritic cell (MDC) levels in HIV-infected subjects on and off antiretroviral therapy. J Clin Immunol. 2006;26:55-64.
    • (2006) J Clin Immunol , vol.26 , pp. 55-64
    • Schmidt, B.1    Fujimura, S.H.2    Martin, J.N.3    Levy, J.A.4
  • 60
    • 33646768572 scopus 로고    scopus 로고
    • Are blockers of gp120/CD4 interaction effective inhibitors of HIV-1 immunopathogenesis?
    • Herbeuval JP, Shearer GM. Are blockers of gp120/CD4 interaction effective inhibitors of HIV-1 immunopathogenesis? AIDS Rev. 2006;8:3-8.
    • (2006) AIDS Rev , vol.8 , pp. 3-8
    • Herbeuval, J.P.1    Shearer, G.M.2
  • 61
    • 4544379282 scopus 로고    scopus 로고
    • Immunomodulatory effects of the HIV-1 gp120 protein on antigen presenting cells: Implications for AIDS pathogenesis
    • Conti L, Fantuzzi L, Del Corno M, Belardelli F, Gessani S. Immunomodulatory effects of the HIV-1 gp120 protein on antigen presenting cells: implications for AIDS pathogenesis. Immunobiology. 2004;209:99-115.
    • (2004) Immunobiology , vol.209 , pp. 99-115
    • Conti, L.1    Fantuzzi, L.2    Del Corno, M.3    Belardelli, F.4    Gessani, S.5
  • 62
    • 27544490285 scopus 로고    scopus 로고
    • Indoleamine 2,3 dioxygenase and regulation of T cell immunity
    • Mellor A. Indoleamine 2,3 dioxygenase and regulation of T cell immunity. Biochem Biophys Res Commun. 2005;338:20-24.
    • (2005) Biochem Biophys Res Commun , vol.338 , pp. 20-24
    • Mellor, A.1
  • 63
    • 0842286646 scopus 로고    scopus 로고
    • IDO and tolerance to tumors
    • Munn DH, Mellor AL. IDO and tolerance to tumors. Trends Mol Med. 2004;10:15-18.
    • (2004) Trends Mol Med , vol.10 , pp. 15-18
    • Munn, D.H.1    Mellor, A.L.2
  • 64
    • 4344629456 scopus 로고    scopus 로고
    • Therapeutic vaccination against HIV
    • Wahren B, Liu M. Therapeutic vaccination against HIV. Expert Rev Vaccines. 2004;3:S179-S188.
    • (2004) Expert Rev Vaccines , vol.3
    • Wahren, B.1    Liu, M.2


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