Immune Selection for Altered Antigen Processing Leads to Cytotoxic T Lymphocyte Escape in Chronic HIV-1 Infection

Journal of Experimental Medicine

Volumn 199, Issue 7, 2004, Pages 905-915

  Draenert, Rika ^a   Le Gall, Sylvie ^a   Pfafferott, Katja J ^b   Leslie, Alasdair J ^b   Chetty, Polan ^c   Brander, Christian ^a   Holmes, Edward C ^f   Chang, Shih Chung ^d   Feeney, Margaret E ^a   Addo, Marylyn M ^a   Ruiz, Lidia ^e   Ramduth, Danni ^c   Jeena, Prakash ^c   Altfeld, Marcus ^a   Thomas, Stephanie ^c   Tang, Yanhua ^a   Verrill, Cori L ^a   Dixon, Catherine ^b   Prado, Julia G ^e   Kiepiela, Photini ^c   Martinez Picado, Javier ^e   Walker, Bruce D ^a   Goulder, Philip J R ^a,b,f   more..

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^c UNIVERSITY OF KWAZULU NATAL   (South Africa)

^d HARVARD MEDICAL SCHOOL   (United States)

^e HOSPITAL UNIVERSITARI GERMANS TRIAS I PUJOL   (Spain)

^f UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Antigen presentation; CD8 T cell responses; Immune evasion; Viral evolution

Indexed keywords

AMINOPEPTIDASE; EPITOPE; HLA ANTIGEN; HLA B57 ANTIGEN; UNCLASSIFIED DRUG;

ANTIGEN PRESENTATION; ANTIGEN RECOGNITION; ARTICLE; CLADISTICS; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DNA FLANKING REGION; ENDOPLASMIC RETICULUM; ENZYME LINKED IMMUNOSPOT ASSAY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOLOGICAL TOLERANCE; PHYLOGENY; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SITE DIRECTED MUTAGENESIS; VIRUS INHIBITION; VIRUS LOAD;

ALLELES; AMINO ACID SEQUENCE; ANTIGEN PRESENTATION; BASE SEQUENCE; CLONE CELLS; DNA, VIRAL; EPITOPES; GENE PRODUCTS, GAG; HIV ANTIGENS; HIV INFECTIONS; HIV-1; HLA-B ANTIGENS; HUMANS; MOLECULAR SEQUENCE DATA; MUTATION; SEQUENCE HOMOLOGY, AMINO ACID; T-LYMPHOCYTES, CYTOTOXIC; VARIATION (GENETICS);

EID: 11144357869     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20031982     Document Type: Article

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