Chimpanzee reservoirs of pandemic and nonpandemic HIV-1

Science

Volumn 313, Issue 5786, 2006, Pages 523-526

  Keele, Brandon F ^a   Van Heuverswyn, Fran ^b   Li, Yingying ^a   Bailes, Elizabeth ^c   Takehisa, Jun ^a   Santiago, Mario L ^a,f   Bibollet Ruche, Frederic ^a   Chen, Yalu ^a   Wain, Louise V ^c   Liegeois, Florian ^b   Loul, Severin ^d   Ngole, Eitel Mpoudi ^d   Bienvenue, Yanga ^d   Delaporte, Eric ^b   Brookfield, John F Y ^c   Sharp, Paul M ^c   Shaw, George M ^a,e   Peeters, Martine ^b   Hahn, Beatrice H ^a  

^a University of Alabama at Birmingham   (United States)

^b INSTITUT DE RECHERCHE POUR LE DÉVELOPPEMENT   (France)

^c UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^d Projet Prevention du Sida au Cameroun PRESICA   (Cameroon)

^e HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACQUIRED IMMUNODEFICIENCY SYNDROME (AIDS); CHIMPANZEE RESERVOIRS; HUMAN IMMUNODEFICIENCY VIRUS (HIV); PAN TROGLODYTES TROGLODYTES;

ANIMAL CELL CULTURE; ANTIBODIES; BIODIVERSITY; IMMUNOLOGY; NUCLEIC ACIDS; VIRUSES;

DISEASES;

MITOCHONDRIAL DNA; NUCLEIC ACID; SIVCPZ ANTIBODY; UNCLASSIFIED DRUG; VIRUS ANTIBODY;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANTIBODY; FECAL PELLET; HUMAN IMMUNODEFICIENCY VIRUS; ISOLATED POPULATION; MAMMAL; NUCLEIC ACID; RESERVOIR; SOCIAL IMPACT;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANIMAL EXPERIMENT; ANTIBODY DETECTION; ARTICLE; CAMEROON; DNA SEQUENCE; ENDANGERED SPECIES; EPIDEMIC; FECES ANALYSIS; HUMAN IMMUNODEFICIENCY VIRUS 1; MOLECULAR ECOLOGY; NONHUMAN; PAN TROGLODYTES; PANDEMIC; PREVALENCE; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SIMIAN IMMUNODEFICIENCY VIRUS; VIRUS CARRIER; VIRUS RESERVOIR; VIRUS STRAIN; ZOONOSIS;

ANIMALS; ANTIBODIES, VIRAL; APE DISEASES; CAMEROON; DISEASE OUTBREAKS; DISEASE RESERVOIRS; DNA, MITOCHONDRIAL; EPIDEMIOLOGY, MOLECULAR; FECES; HAPLOTYPES; HIV ANTIBODIES; HIV INFECTIONS; HIV-1; HUMANS; MOLECULAR SEQUENCE DATA; PAN TROGLODYTES; PHYLOGENY; PREVALENCE; RECOMBINATION, GENETIC; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIMIAN IMMUNODEFICIENCY VIRUS;

AFRICA; CAMEROON; SUB-SAHARAN AFRICA; WEST AFRICA;

HUMAN IMMUNODEFICIENCY VIRUS 1; PAN TROGLODYTES; PAN TROGLODYTES TROGLODYTES; SIMIAN IMMUNODEFICIENCY VIRUS;

EID: 33745059199     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1126531     Document Type: Article

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23. We thank the Cameroonian Ministries of Health, Environment and Forestry, and Research for permission to perform this study; J. Dupain, C. Neel, and M. Epanda (Projet Grands Singes); L. Usongo, D. Dontego, F. Espedi, and B. Tshikangwa (World Wildlife Fund); and G. Etoga and D. M'bohand (Ministry of Environment and Forestry) for assistance in the field. This work was supported in part by the NIH (grants RO1 AI50529, RO1 AI58715, and P30 AI 27767), the Bristol Myers Freedom to Discover Program, the Institut de Recherche pour le Développement, and the Howard Hughes Medical Institute. New SIVcpzPtt sequences are available at GenBank under accession numbers DQ370366-DQ370419 and DQ373063-DQ373066; chimpanzee mtDNA sequences are available under DQ367532-DQ367613 and DQ370307-DQ370365.