Tyrosine kinases and inflammatory signalling

Current Molecular Medicine

Volumn 9, Issue 1, 2009, Pages 69-85

  Page, Theresa H ^a   Smolinska, Maria ^a,b   Gillespie, Justin ^a   Urbaniak, Anna M ^a   Foxwell, Brian M J ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

Cytokines; Inflammation; Macrophages; Rheumatoid Arthritis; Tyrosine kinases

Indexed keywords

CYTOKINE; DECTIN 1; FOCAL ADHESION KINASE 2; HEMATOPOIETIC CELL KINASE; I KAPPA B KINASE ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTEGRIN; INTERLEUKIN 10; INTERLEUKIN 6; INTERLEUKIN 8; JANUS KINASE; MONOCYTE CHEMOTACTIC PROTEIN 1; MYELOID DIFFERENTIATION FACTOR 88; PROTEIN KINASE BLK; PROTEIN KINASE FYN; PROTEIN KINASE LCK; PROTEIN KINASE LYN; PROTEIN KINASE TEC; PROTEIN KINASE YES; PROTEIN KINASE YRK; PROTEIN TYROSINE KINASE; STAT PROTEIN; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; IMMUNOLOGICAL ADJUVANT; PROTEIN KINASE SYK; SIGNAL PEPTIDE; TEC PROTEIN TYROSINE KINASE; TEC PROTEIN-TYROSINE KINASE;

ANTIINFLAMMATORY ACTIVITY; B LYMPHOCYTE; CELL MIGRATION; CYTOKINE PRODUCTION; ENZYME ACTIVITY; GENE ACTIVATION; HUMAN; INFLAMMATION; MACROPHAGE; MONOCYTE; NEUTROPHIL; NONHUMAN; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; REVIEW; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; T LYMPHOCYTE; ANIMAL; ANTIGEN ANTIBODY COMPLEX; BIOSYNTHESIS; CELL MOTION; CHEMISTRY; CHRONIC DISEASE; GENE EXPRESSION; IMMUNOLOGY; METABOLISM; MOUSE;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIGEN-ANTIBODY COMPLEX; CELL MOVEMENT; CHRONIC DISEASE; CYTOKINES; FOCAL ADHESION KINASE 2; GENE EXPRESSION; HUMANS; INFLAMMATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; JANUS KINASES; MICE; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS C-HCK; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; TOLL-LIKE RECEPTORS;

EID: 62749113471     PISSN: 15665240     EISSN: None     Source Type: Journal    
DOI: 10.2174/156652409787314507     Document Type: Review

References (196)

1. Balkwill, F. and Mantovani, A. (2001) Lancet, 357, 539-545.
2. Lee, M.S. and Kim, Y.J. (2007) Annu. Rev. Biochem., 76, 447-480.
3. O'Neill, L.A. (2006) Curr. Opin. Immunol., 18, 3-9.
4. Murray, P.J. (2006) Curr. Opin. Pharmacol., 6, 379-386.
5. Feldmann, M., Brennan, F.M., Foxwell, B.M., Taylor, P.C., Williams, R.O. and Maini, R.N. (2005) J. Autoimmun., 25 Suppl, 26-28.
6. Kavanaugh, A. (2007) Bull. NYU Hosp. Jt. Dis., 65 (Suppl 1), S16-20.
7. Novogrodsky, A., Vanichkin, A., Patya, M., Gazit, A., Osherov, N. and Levitzki, A. (1994) Science, 264, 1319-1322.
8. Thomas, S.M. and Brugge, J.S. (1997) Annu. Rev. Cell Dev. Biol., 13, 513-609.
9. Ingley, E. (2008) Biochim. Biophys. Acta, 1784, 56-65.
10. Okutani, D., Lodyga, M., Han, B. and Liu, M. (2006) Am. J. Physiol. Lung Call. Mol. Physiol., 291, L129-141.
11. Boggon, T.J. and Eck, M.J. (2004) Oncogene, 23, 7918-7927.
12. Carreno, S., Gouze, M.E., Schaak, S., Emorine, L.J. and Maridonneau-Parini, I. (2000) J. Biol. Chem., 275, 36223-36229.
13. McCabe, J.B. and Berthiaume, L.G. (1999) Mol. Biol. Cell, 10, 3771-3786.
14. Rash, M.D. (1999) Biochim. Biophys. Acta, 1451, 1-16.
15. Veillette, A., Bookman, M.A., Horak, E.M. and Bolen, J.B. (1988) Cell, 55, 301-308.
16. Feng, S., Chen, J.K., Yu, H., Simon, J.A. and Schreiber, S.L. (1994) Science, 266, 1241-1247.
17. Waksman, G., Kominos, D., Robertson, S.C., Pant, N., Baltimore, D., Birge, R.B., Cowbum, D., Hanafusa, H., Mayer, B.J., Overduin, M. and et al. (1992) Nature, 358, 646-653.
18. Williams, J.C., Weijland, A., Gonfloni, S., Thompson, A., Courtneidge, S.A., Superti-Furga, G. and Wierenga, R.K. (1997) J. Mol. Biol., 274, 757-775.
19. Xu, W., Harrison, S.C. and Eck, M.J. (1997) Nature, 385, 595-602.
20. Okada, M., Nada, S., Yamanashi, Y., Yamamoto, T. and Nakagawa, H. (1991) J. Biol. Chem., 266, 24249-24252.
21. Rawlings, D.J., Scharenberg, A.M., Park, H., Wahl, M.I., Lin, S., Kato, R.M., Fluckiger, A.C., Witte, O.N. and Kinet, J.P. (1996) Science, 271, 822-825.
22. Chan, A.C., Iwashima, M., Turck, C.W. and Weiss, A. (1992) Cell, 71, 649-662.
23. Hazold, K., Masuda, N., Funami, K., Sukenobu, N., Matsumoto, M., Akira, S., Takeda, K., Seya, T. and Hazeki, O. (2003) Eur. J. Immunol., 33, 740-747.
24. Qian, D., Lev, S., van Oers, N.S., Dikic, I., Schlessinger, J. and Weiss, A. (1997) J. Exp. Med., 185, 1253-1259.
25. Boulet, I., Ralph, S., Stanley, E., Lock, P., Dunn, A.R., Green, S.P. and Phillips, W.A. (1992) Oncogene, 7, 703-710.
26. Yi, T.L. and Willman, C.L. (1989) Oncogene, 4, 1081-1087.
27. Ziegler, S.F., Wilson, C.B. and Perlmutter, R.M. (1988) J. Exp. Med., 168, 1801-1810.
28. Fan, H., Teti, G., Ashton, S., Guyton, K., Tempel, G.E., Halushka, P.V. and Cook, J.A. (200S) Cytokine, 22, 126-133.
29. Orlicek, S.L., Hanke, J.H. and English, B.K. (1999) Shock, 12, 350-354.
30. Smolinska, M.J., Horwood, N.J., Page, T.H., Smallie, T. and Foxwell, B.M. (2008) Mol. Immunol., 45, 990-1000.
31. Adamo, R., Sokol, S., Soong, G., Gomez, M.I. and Prince, A. (2004) Am. J. Respir. Cell Mol. Biol., 30, 627-634.
32. Stovall, S.H., Yi, A.K., Meals, E.A., Talati, A.J., Godambe, S.A. and English, B.K. (2004) J. Siol. Chem., 279, 13809-13816.
33. Severgnini, M., Takahashi, S., Tu, P., Perides, G., Homer, R.J., Jhung, J.W., Bhavsar, D., Cochran, B.H. and Simon, A.R. (2005) Am. J. Respir. Crit. Care Med., 171, 858-867.
34. Beaty, C.D., Franklin, T.L., Uehara, Y. and Wilson, C.B. (1994) Eur. J. Immunol., 24, 1278-1284.
35. Stafanova, I., Corcoran, M.L., Horak, E.M., Wahl, L.M., Bolen, J.B. and Horak, I.D. (1993) J. Biol. Chem., 268, 20725-20728.
36. English, B.K., Ihle, J.N., Myracle, A. and Yi, T. (1993) J. Exp. Med., 178, 1017-1022.
37. Lowell, C.A. and Berton, G. (1998) Proc. Natl. Acad. Sci. U.S.A., 95, 7580-7584.
38. Lowell, C.A., Soriano, P. and Varmus, H.E. (1994) Genes Dev., 8, 387-398.
39. Ernst, M., Inglese, M., Scholz, G.M., Harder, K.W., Clay, F.J., Bozinovski, S., Waring, P., Darwiche, R., Kay, T., Sly, P., Collins, R., Turner, D., Hibbs, M.L., Anderson, G.P. and Dunn, A.R. (2002) J. Exp. Med., 196, 589-604.
40. Meng, F. and Lowell, C.A. (1997) J. Exp. Med., 185, 1661-1670.
41. Majeed, M., Caveggion, E., Lowell, C.A. and Berton, G. (2001) J. Leukoc. Biol., 70, 801-811.
42. Lee, J.Y., Lowell, C.A., Lemay, D.G., Youn, H.S., Rhea, S.H., Sohn, K.H., Jang, B., Ye, J., Chung, J.H. and Hwang, D.H. (2005) Biochem. Pharmacol., 70, 1231-1240.
43. Suen, P.W., Illic, D., Caveggion, E., Berton, G., Damsky, C.H. and Lowell, C.A. (1999) J. Cell Sci., 112 (Pt 22), 4067-4078.
44. Lee, H.S., Moon, C., Lee, H.W., Park, E.M., Cho, M.S. and Kang, J. L. (2007) J. Immunol., 179, 7001-7011.
45. Medvedev, A.E., Piao, W., Shoenfelt, J., Rhee, S.H., Chen, H., Basu, S., Wahl, L.M., Fenton, M.J. and Vogel, S.N. (2007) J. Biol. Chem., 282, 16042-16053.
46. Beraud, C., Henzel, W.J. and Baeuerle, P.A. (1999) Proc. Natl. Acad. Sci. U.S.A., 96, 429-434.
47. Imbert, V., Rupec, R.A., Livolsi, A., Pahl, H.L., Traenckner, E.B., Mueller-Dieckmann, C., Farahifar, D., Rossi, B., Auberger, P., Baeuerle, P.A. and Peyron, J.F. (1996) Cell, 86, 787-798.
48. Napolitani, G., Bortoletto, N., Racioppi, L., Lanzavecchia, A. and D'Oro, U. (2003) Eur. J. Immunol., 33, 2832-2841.
49. Ingley, E. and Klinken, S.P. (2006) Growth Factors, 24, 89-95.
50. Kleemann, R., Zadelaar, S. and Kooistra, T. (2008) Cardiovasc. Res., 79, 360-376.
51. Morel, J.C., Park, C.C., Zhu, K., Kumar, P., Ruth, J.H. and Koch, A.E. (2002) J. Biol. Chem., 277, 34679-34691.
52. Chandrasekar, B., Mummidi, S., Valente, A.J., Patel, D.N., Bailey, S.R., Freeman, G.L., Hatano, M., Tokuhisa, T. and Jensen, L.E. (2005) J. Biol. Chem., 280, 26263-26277.
53. Hallek, M., Neumann, C., Schaffer, M., Danhauser-Riedl, S., von Bubnoff, N., de Vos, G., Druker, B.J., Yasukawa, K., Griffin, J.D. and Emmerich, B. (1997) Exp. Hematol., 25, 1367-1377.
54. Schaeffer, M., Schneiderbauer, M., Weidler, S., Tavares, R., Warmuth, M., de Vos, G. and Hallek, M. (2001) Mol. Cell. Biol., 21, 8068-8081.
55. Duval, M., Le Boeuf, F., Huot, J. and Grafton, J.P. (2007) Mol. Biol. Cell, 18, 4659-4668.
56. Giorgetti-Peraldi, S., Murdaca, J., Mas, J.C. and Van Obberghen, E. (2001) Oncogene, 20, 3959-3968.
57. Mann, H., Ishikawa, F., Nishida, J., Hirai, H. and Takaku, F. (1990) Oncogene, 5, 1781-1786.
58. Smith, C.I., Islam, T.C., Mattsson, P.T., Mohamed, A.J., Nore, B.F. and Vihinen, M. (2001) Bioessays, 23, 436-446.
59. de Wears, M., Verschuren, M.C., Kraakman, M.E., Mensink, R.G., Schuurman, R.K., van Dongen, J.J. and Hendriks, R.W. (1993) Eur. J. Immunol., 23, 3109-3114.
60. Smith, C.I., Baskin, B., Humire-Greiff, P., Zhou, J.N., Olsson, P.G., Maniar, H.S., Kjellen, P., Lambris,J.D., Christensson, B., Hammarstrom, L. (1994) J. Immunol., 152, 557-565.
61. August, A., Gibson, S., Kawakami, Y., Kawakami, T., Mills, G.B. and Dupont, B. (1994) Proc. Natl. Acad. Sci. U.S.A., 91, 9347-9351.
62. Hu, Q., Davidson, D., Schwartzberg, P.L., Macchiarini, F., Lenardo, M.J., Bluestone, J.A. and Matis, L.A. (1995) J. Biol. Chem., 270, 1928-1934.
63. Sato, K., Mano, H., Ariyama, T., Inazawa, J., Yazaki, Y. and Hirai, H. (1994) Leukemia, 8, 1663-1672.
64. Fukuda, M., Kojima, T., Kabayama, H. and Mikoshiba, K. (1996) J. Biol. Chem., 271, 30303-30306.
65. Rawlings, D.J., Saffran, D.C., Tsukada, S., Largaespada, D.A., Grimaldi, J.C., Cohen, L., Mohr, R.N., Bazan, J.F., Howard, M., Copeland, N.G. Jenkins, N. and Witte, O.N. (1993) Science, 261, 358-361.
66. Debnath, J., Chamorro, M., Czar, M.J., Schaeffer, E.M., Lenardo, M.J., Varmus, H.E. and Schwartzberg, P.L. (1999) Mol. Cell. Biol., 19, 1498-1507.
67. Miller, A.T. and Berg, L.J. (2002) Curr. Opin. Immunol., 14, 331-340.
68. Valiaho, J., Smith, C.I. and Vihinen, M. (2006) Hum. Mutat., 27, 1209-1217.
69. Middendorp, S., Dingjan, G.M., Maas, A., Dahlenborg, K. and Hendriks, R.W. (2003) J. Immunol., 171, 5988-5996.
70. Saito, K., Tolias, K.F., Saci, A., Koon, H.B., Humphries, L.A., Scharenberg, A., Rawlings, D.J., Kinet, J.P. and Carpenter, C.L. (2003) Immunity, 19, 669-678.
71. Hao, S., Qi, Q., Hu, J. and August, A. (2006) FEBS Lett., 580, 2691-2697.
72. Ferguson, K.M., Lemmon, M.A., Sigler, P.B. and Schlessinger, J. (1995) Nat. Struct. Biol., 2, 715-718.
73. Alexandropoulos, K., Cheng, G. and Baltimore, D. (1995) Proc. Natl. Acad. Sci. U.S.A., 92, 3110-3114.
74. Cheng, G., Ye, Z.S. and Baltimore, D. (1994) Proc. Natl. Acad. Sci. U.S.A., 91, 8152-8155.
75. Wahl, M.I., Fluckiger, A.C., Kato, R.M., Park, H., Witte, O.N. and Rawlings, D.J. (1997) Proc. Natl. Acad. Sci. U.S.A., 94, 11526-11533.
76. Khan, W.N., Alt, F.W., Gerstein, R.M., Malynn, B.A., Larsson, I., Rathbun, G., Davidson, L., Muller, S., Kantor, A.B., Herzenberg, L.A. Rosen, F.S. and Sideras, P. (1995) Immunity, 3, 283-299.
77. Mukhopadhyay, S., Mohanty, M., Mangle, A., George, A., Bal, V., Rath, S. and Ravindran, B. (2002) J. Immunol., 168, 2914-2921.
78. Jansson, L. and Holmdahl, R. (1993) Clin. Exp. Immunol., 94, 459-465.
79. Horwood, N.J., Mahon, T., McDaid, J.P., Campbell, J., Mano., H., Brennan, F.M., Webster, D. and Foxwell, B.M. (2003) J. Exp. Med., 157, 1603-1611.
80. Doyle, S.L., Jefferies, C.A., Feighery, C. and O'Neill, L.A. (2007) J. Biol. Chem., 282, 36953-36960.
81. Jefferies, C.A., Doyle, S., Brunner, C., Dunne, A., Brint, E., Wietek, C., Watch, E., Wirth, T. and O'Neill, L.A. (2003) J. Biol. Chem., 278, 26258-26264.
82. Taneichi, H., Kanegane, H., Sira, M.M., Futatani, T., Agematsu, K., Sako, M., Kaneko, H., Kondo, N., Kaisho, T. and Miyawaki, T. (2008) Clin. Immunol., 126, 148-154.
83. Hasan, M., Lopez-Herrera, G., Blomberg, K.E., Lindvall, J.M., Berglof, A., Smith, C.I. and Vargas, L. (2008) Immunology, 123, 289-249.
84. Schmidt, N.W., Thieu, V.T., Mann, B.A., Ahyi, A.N. and Kaplan, M.H. (2006) J. Immunol., 177, 7203-7210.
85. Gray, P., Dunne, A., Brikos, C., Jefferies, C.A., Doyle, S.L. and O'Neill, L.A. (2006) J. Biol. Chem., 281, 10489-10495.
86. Mansell, A., Smith, R., Doyle, S.L., Gray, P., Fenner, J.E., Crack, P.J., Nicholson, S.E., Hilton, D.J., O'Neill, L.A. and Hertzog, P.J. (2006) Nat. Immunol., 7, 148-155.
87. Lee, S.H., Kim, T., Jeong, D., Kim, N. and Choi, Y. (2008) J. Biol. Chem., 283, 11526-11534.
88. Doyle, S.L., Jefferies, C.A. and O'Neill, L.A. (2005) J. Biol. Chem., 280, 23496-23501.
89. Horwood, N.J., Page, T.H., McDaid, J.P., Palmer, C.D., Campbell, J., Mahon, T., Brennan, F.M., Webster, D. and Foxwell, B. M. (2006) J. Immunol., 176, 3635-3641.
90. Palmer, C.D., Mutch, B.E., Workman, S., McDaid, J.P., Horwood, N.J. and Foxwell, B.M. (2008) Blood, 111, 1781-1788.
91. Sochorova, K., Horvath, R., Rozkova, D., Litzman, J., Bartunkova, J., Sediva, A. and Spisek, R. (2007) Blood, 109, 2553-2556.
92. Semaan, N., Alsaleh, G., Gottenberg, J.E., Wachsmann, D. and Sibilia, J. (2008) J. Immunol., 180, 3485-3491.
93. Matsuda, T., Takahashi-Tezuka, M., Fukada, T., Okuyama, Y., Fujitani, Y., Tsukada, S., Mano, H., Hirai, H., Witte, O.N. and Hirano, T. (1995) Blood, 65, 627-633.
94. He, Y., Luo, Y., Tang, S., Rajantie, I., Salven, P., Heil, M., Zhang, R., Luo, D., Li, X., Chi, H., Yu, J., Carmeliet, P., Schaper, W., Sinusas, A.J., Sessa, W.C., Alitalo, K. and Min, W. (2006) J. Clin. Invest., 116, 2344-2355.
95. Pan, S., An, P., Zhang, R., He, X., Yin, G. and Min, W. (2002) Mol. Cell. Biol., 22, 7512-7523.
96. Coopman, P.J., Do, M.T., Barth, M., Bowden, E.T., Hayes, A.J., Basyuk, E., Biancato, J.K., Vezza, P.R., McLeskey, S.W., Mangeat, P.H. and Mueller, S.C. (2000) Nature, 406, 742-747.
97. Takada, Y. and Aggarwal, B.B. (2004) J. Immunol., 173, 1066-1077.
98. Adachi, T., Wienands, J., Tsubata, T. and Kurosaki, T. (2007) Biochem. Biophys. Res. Commun., 364, 111-117.
99. Papp, E., Tse, J.K., Ho, H., Wang, S., Shaw, D., Lee, S., Barnett, J., Swinney, D.C. and Bradshaw, J.M. (2007) Biochemistry, 46, 15103-15114.
100. Johnson, S.A., Pleiman, C.M., Pao, L., Schneringer, J., Hippen, K. and Cambier, J.C. (1995) J. Immunol., 155, 4596-4603.
101. Kihara, H. and Siraganian, R.P. (1994) J. Biol. Chem., 269, 22427-22432.
102. Siraganian, R.P., Zhang, J., Suzuki, K. and Sada, K. (2002) Mol. Immunol., 38, 1229-1233.
103. Fitzer-Attas, C.J., Lowry, M., Crowley, M.T., Finn, A.J., Meng, F., DeFranco, A.L. and Lowell, C.A. (2000) J. Exp. Med., 191, 669-682.
104. Underhill, D.M. and Goodridge, H.S. (2007) Trends Immunol., 28, 66-73.
105. Crowley, M.T., Costello, P.S., Fitzer-Attas, C.J., Turner, M., Meng, F., Lowell, C., Tybulewicz, V.L. and DeFranco, A.L. (1997) J. Exp. Med., 186, 1027-1039.
106. Kulathu, Y., Hobeika, E., Turchinovich, G. and Reth, M. (2008) EMBO J., 27, 1333-1344.
107. Turner, M., Mee, P.J., Costello, P.S., Williams, O., Price, A.A., Duddy, L.P., Furlong, M.T., Geahlen, R.L. and Tybulewicz, V. L. (1995) Nature, 378, 298-302.
108. Costello, P.S., Turner, M., Walters, A.E., Cunningham, C.N., Bauer, P.H., Downward, J. and Tybulewicz, V.L. (1996) Oncogene, 13, 2595-2605.
109. Abtahian, F., Guerriero, A., Sebzda, E., Lu, M.M., Zhou, R., Mocsai, A., Myers, E.E., Huang, B., Jackson, D.G., Ferrari, V.A., Tybulewicz, V., Lowell, C.A., Lepore, J.J., Koretzky, G.A. and Kahn, M.L. (2003) Science, 299, 247-251.
110. Frommhold, D., Mannigel, I., Schymeinsky, J., Mocsai, A., Poeschl, J., Walzog, B. and Sperandio, M. (2007) BMC Immunol., 8, 31.
111. Turner, M., Schweighoffer, E., Colucci, F., Di Santo, J.P. and Tybulewicz, V.L. (2000) Immunol. Today, 21, 148-154.
112. Crowley, M.T., Harmer, S.L. and DeFranco, A.L. (1996) J. Biol. Chem., 271, 1145-1152.
113. Ulanova, M., Asfaha, S., Stenton, G., Lint, A., Gilbertson, D., Schreiber, A. and Befus, D. (2007) J. Endotoxin Res., 13, 117-125.
114. Chaudhary, A., Fresquez, T.M. and Naranjo, M.J. (2007) Immunol. Cell Biol., 85, 249-256.
115. Khandaker, M.H., Xu, L., Rahimpour, R., Mitchell, G., DeVries, M.E., Pickering, J.G., Singhal, S.K., Feldman, R.D. and Kelvin, D.J. (1998) J. Immunol., 161, 1930-1938.
116. Arndt, P.G., Suzuki, N., Avdi, N.J., Malcolm, K.C. and Worthen, G.S. (2004) J. Biol. Chem., 279, 10883-10891.
117. Yamada, T., Fujieda, S., Yanagi, S., Yamamura, H., Inatome, R., Sunaga, H. and Saito, H. (2001) J. Immunol., 166, 538-543.
118. Rogers, N.C., Slack, E.C., Edwards, A.D., Nolte, M.A., Schulz, O., Schweighoffer, E., Williams, D.L., Gordon, S., Tybulewicz, V.L., Brown, G.D. and Reis e Sousa, C. (2005) Immunity, 22, 507-517.
119. Bouchon, A., Dietrich, J. and Colonna, M. (2000) J. Immunol., 164, 4991-4995.
120. Bleharski, J.R., Kiessler, V., Buonsanti, C., Sieling, P.A., Stenger, S., Colonna, M. and Modlin, R.L. (2003) J. Immunol., 170, 3812-3818.
121. Bouchon, A., Facchetti, F., Weigand, M.A. and Colonna, M. (2001) Nature, 410, 1103-1107.
122. Netea, M.G., Azam, T., Ferwerda, G., Girardin, S.E., Kim, S.H. and Dinarello, C.A. (2006) J. Leukoc. Biol., 80, 1454-1461.
123. Dower, K., Ellis, D.K., Saraf, K., Jelinsky, S.A. ahd Lin, L.L. (2008) J. Immunol., 180, 3520-3534.
124. Turnbull, I.R. and Colonna, M. (2007) Nat. Rev. Immunol., 7, 155-161.
125. Omatowska, M., Azim, A.C., Wang, X., Christman, J.W., Xiao, L., Joo, M. and Sadikot, R.T. (2007) Am. J. Physiol. Lung Cell. Mol. Physiol., 293, L1377-1384.
126. Hamerman, J.A., Jarjoura, J.R., Humphrey, M.B., Nakamura, M.C., Seaman, W.E. and Lanier, L.L. (2006) J. Immunol., 177, 2051-2055.
127. Brown, G.D. (2006) Nat. Rev. Immunol., 6, 33-43.
128. Gantner, B.N., Simmons, R.M., Canavera, S.J., Akira, S. and Underhill, D.M. (2003) J. Exp. Med., 197, 1107-1117.
129. Dennehy, K.M., Ferwerda, G., Faro-Trindade, I., Pyz, E., Willment, J.A., Taylor, P.R., Kerrigan, A., Tsoni, S.V., Gordon, S., Meyer-Wentrup, F., Adema, G.J., Kullberg, B.J., Schweighoffer, E., Tybulewicz, V., Mora-Montes, H.M., Gow, N.A. Williams, D.L., Netea, M.G. and Brown, G.D. (2008) Eur. J. Immunol., 38, 500-506.
130. Underhill, D.M., Rossnagle, E., Lowell, C.A. and Simmons, R.M. (2005) Blood, 106, 2543-2550.
131. LeibundGut-Landmann, S., Gross, O., Robinson, M.J. Osorio, F., Slack, E.C., Tsoni, S.V., Schweighoffer, E., Tybulewicz, V., Brown, G.D., Ruland, J. and Reis e Sousa, C, (2007) Nat. Immunol., 8, 630-638.
132. Edwards, J.C., Szczepanski, L., Szechinski, J., Filipowicz-Sosnowska, A., Emery, P., Close, D.R., Stevens, R.M. and Shaw, T. (2004) N. Engl. J. Med., 350, 2572-2581.
133. Ji, H., Ohmura, K., Mahmood, U., Lee, D.M., Hofhuis, F.M., Boackle, S.A., Takahashi, K., Holers, V.M., Walport, M., Gerard, C., Ezekowitz, A., Carroll, M.C., Brenner, M., Weissleder, R., Verbeek, J.S., Duchatelle, V., Degott, C., Benoist, C. and Mathis, D. (2002) Immunity, 16, 157-168.
134. Kagari, T., Tanaka, P., Doi, H. and Shimozato, T. (2003) J. Immunol., 170, 4318-4324.
135. Darby, C., Geahlen, R.L. and Schreiber, A.D. (1994) J. Immunol., 152, 5429-5437.
136. Durden, D.L. and Liu, Y.B. (1994) Blood, 84, 2102-2108.
137. Kiefer, F., Brumell, J., Al-Alawi, N., Latour, S., Cheng, A., Veillette, A., Grinstein, S. and Pawson, T. (1998) Mol. Cell. Biol., 18, 4209-4220.
138. Braselmann, S., Taylor, V., Zhao, H., Wang, S., Sylvain, C., Baluom, M., Qu, K., Herlaar, E., Lau, A., Young, C., Wong, B.R., Lovell, S., Sun, T., Park, G., Argade, A., Jurcevic, S., Pine, P., Singh, R., Grossbard, E.B., Payan, D. G. and Masuda, E.S. (2006) J. Pharmacol. Exp. Ther., 319, 998-1008.
139. Pine, P.R., Chang, B., Schoettler, N., Banquerigo, M.L., Wang, S., Lau, A., Zhao, F., Grossbard, E.B., Payan, D.G. and Brahn, E. (2007) Clin. Immunol., 124, 244-257.
140. Sieg, D.J., Ilic, D., Jones, K.C., Damsky, C.H., Hunter, T. and Schlaepfer, D.D. (1998) EMBO J., 17, 5933-5947.
141. Avraham, H., Park, S.Y., Schinkmann, K. and Avraham, S. (2000) Cell. Signal., 12, 123-133.
142. Duong, L.T., Nakamura, I., Lakkakorpi, P.T., Lipfert, L., Bett, A.J. and Rodan, G.A. (2001) J. Biol. Chem., 276, 7484-7492.
143. Williams, L.M. and Ridley, A.J. (2000) J. Immunol., 164, 2028-2036.
144. Achuthan, A., Elsegood, C., Masendycz, P., Hamilton, J.A. and Scholz, G.M. (2006) Cell. Signal., 18, 2252-2261.
145. Heidkamp, M.C., Scully, B.T., Vijayan, K., Engman, S.J., Szotek, E.L. and Samarel, A.M. (2005) Am. J. Physiol. Cell Physiol., 289, C471-482.
146. Vitale, S., Schmid-Alliana, A., Breuil, V., Pomeranz, M., Millet, M.A., Rossi, B. and Schmid-Antomarchi, H. (2004) J. Immunol., 172, 585-592.
147. Anand, A.R., Cucchiarini, M., Terwilliger, E.F. and Ganju, R.K. (2008) J. Immunol., 180, 5636-6644.
148. Fuortes, M., Melchior, M., Han, H., Lyon, G.J. and Nathan, C. (1999) J. Clin. Invest., 104, 327-335.
149. Han, H., Fuortes, M. and Nathan, C. (2003) J. Exp. Med., 197, 63-75.
150. Okigaki, M., Davis, C., Falasca, M., Harroch, S., Felsenfeld, D.P., Sheetz, M.P. and Schlessinger, J. (2003) Proc. Natl. Acad. Sci. U.S.A., 100, 10740-10745.
151. Salgia, R., Avraham, S., Pisick, E., Li, J.L., Raja, S., Greenfield, E.A., Sattler, M., Avraham, H. and Griffin, J.D. (1996) J. Biol, Chem., 271, 31222-31226.
152. Yamasaki, M., Arai, H., Ashida, N., Ishii, K. and Kita, T. (2001) Biochem. J., 355, 751-756.
153. Baker, S.J., Rene, S.G. and Reddy, E.P. (2007) Oncogene, 26, 6724-6737.
154. Wojchowski, D.M., Gregory, R.C., Miller, C.P., Pandit, A.K. and Pircher, T.J. (1999) Exp. Cell Res., 253, 143-156.
155. Schindler, C., Levy, D.E. and Decker, T. (2007) J. Biol. Chem., 282, 20059-20063.
156. Kisseleva, T., Bhattacharya, S., Braunstein, J. and Schindler, C.W. (2002) Gene, 285, 1-24.
157. O'Shea, J.J. and Murray, P.J. (2008) Immunity, 28, 477-487.
158. Minegishi, Y., Saito, M., Morio, T., Watanabe, K., Agematsu, K., Tsuchiya, S., Takada, H., Hara, T., Kawamura, N., Ariga, T., Kaneko, H., Kondo, N., Tsuge, I., Yachie, A., Sakiyama, Y., Iwata, T., Bessho, F., Ohishi, T., Joh, K., Imai, K., Kogawa, K., Shinohara, M., Fujieda, M., Wakiguchi, H., Pasic, S., Abinun, M., Ochs, H.D., Renner, F.D., Jansson, A., Belohradsky, B.H., Metin, A., Shimizu, N., Mizutani, S., Miyawaki, T., Nonoyama, S. and Karasuyama, H. (2006) Immunity, 25, 745-755.
159. Karaghiosoff, M., Steinbom, R., Kovarik, P., Kriegshauser, G., Baccarini, M., Donabauer, B., Reichart, U., Kolbe, T., Bogdan, C., Leanderson, T., Levy, D., Decker, T. and Muller, M. (2003) Nat. Immunol., 4, 471-477.
160. Idzerda, R.L., March, C.J., Mosley, B., Lyman, S.D., Vanden Bos, T., Gimpel, S.D., Din, W.S., Grabstein, K.H., Widmer, M.B., Park, L.S. and et al. (1990) J. Exp. Med., 171, 861-873.
161. Aman, M.J., Tayebi, N., Obiri, N.I., Puri, R.K., Modi, W.S. an Leonard, W.J. (1996) J. Biol. Chem., 271, 29265-29270.
162. Takeda, K., Kishimoto, T. and Akira, S. (1997) J. Mol. Med., 75, 317-326.
163. Usacheva, A., Kotenko, S., Witte, M.M. and Colamonici, O.R. (2002) J. Immunol., 169, 1302-1308.
164. Albanesi, O, Fairchild, H.R., Madonna, S., Scarponi, C., De Pita, O., Leung, D.Y. and Howell, M.D. (2007) J. Immunol., 179, 984-992.
165. Dickensheets, H., Vazquez, N., Sheikh, F., Gingras, S., Murray, P.J., Ryan, J.J. and Donnelly, R.P. (2007) Genes Immun., 8, 21-27.
166. Ohmori, Y. and Hamilton, T.A. (2000) J. Biol. Chem., 275, 38095-38103.
167. Essner, R., Rhoades, K., McBride, W.H., Morton, D.L. and Economou, J.S. (1989) J. Immunol., 142, 3857-3861.
168. Minty, A., Chalon, P., Derocq, J.M., Dumont, X., Guillemot, J.C., Kaghad, M., Labit, C., Leplatois, P., Liauzun, P., Miloux, B. and et al. (1993) Nature, 362, 248-250.
169. te Velde, A.A., Huijbens, R.J., Heije, K., de Vries, J.E. and Figdor, C.G. (1990) Blood, 76, 1392-1397.
170. Woods, J.M., Katschke, K.J., Jr., Tokuhira, M., Kurata, H., Arai, K.I., Campbell, P.L. and Koch, A.E. (2000) J. Immunol., 165, 2755-2763.
171. Bennett, B.L., Cruz, R., Lacson, R.G. and Manning, A.M. (1997) J. Biol. Chem., 272, 10212-10219.
172. Chabaud, M., Page, G. and Miossec, P. (2001) J. Immunol., 167, 6015-6020.
173. Fenton, M.J., Buras, J.A. and Donnelly, R.P. (1992) J. Immunol., 149, 1283-1288.
174. Bessis, N., Cottard, V., Saidenberg-Kermanach, N., Lemeiter, D., Fournier, C. and Boissier, M.C. (2002) J. Gene Med., 4, 300-307.
175. Kim, S.H., Kim, S., Evans, C.H., Ghivizzani, S.C., Oligino, T. and Robbins, P.D. (2001) J. Immunol., 166, 3499-3505.
176. Woods, J.M., Katschke, K.J., Volin, M.V., Ruth, J.H., Woodruff, D.C., Amin, M.A., Connors, M.A., Kurata, H., Arai, K., Haines, G.K., Kumar, P. and Koch, A.E. (2001) J. Immunol., 166, 1214-1222.
177. Donnelly, R.P., Fenton, M.J., Kaufman, J.D. and Gerrard, T.L. (1991) J. Immunol., 146, 3431-3436.
178. Mijatovic, T., Kruys, V., Caput, D., Defrance, P. and Huez, G. (1997) J. Biol. Chem., 272, 14394-14398.
179. Starr, R., Willson, T.A., Viney, E.M., Murray, L.J., Rayner, J.R., Jenkins, B.J., Gonda, T.J., Alexander, W.S., Metcalf, D., Nicola, N.A. and Hilton, D.J. (1997) Nature, 387, 917-921.
180. Moore, K.W., de Waal Malefyt, R., Coffman, R.L. and O'Garra, A. (2001) Annu. Rev. Immunol., 19, 683-765.
181. Spencer, S.D., Di Marco, F., Hooley, J., Pitts-Meek, S., Bauer, M., Ryan, A.M., Sordat, B., Gibbs, V.C. and Aguet, M. (1998) J. Exp. Med., 187, 571-578.
182. Dickensheets, H.L., Freeman, S.L., Smith, M.F. and Donnelly, R.P. (1997) Blood, 90, 4162-4171.
183. Jenkins, J.K., Malyak, M. and Arend, W.P. (1994) Lymphokine Cytokine Res., 13, 47-54.
184. Ito, S., Ansari, P., Sakatsume, M., Dickensheets, H., Vazquez, N., Donnelly, R.P., Larner, A.C. and Finbloom, D.S. (1999) Blood, 93, 1456-1463.
185. Lee, T.S. and Chau, L.Y. (2002) Nat Med., 8, 240-246.
186. Williams, L.M., Ricchetti, G., Sarma, U., Smallie, T. and Foxwell, B.M. (2004) Immunology, 113, 281-292.
187. Kuhn, R., Lohler, J., Rennick, D., Rajewsky, K. and Muller, W. (1993) Cell, 75, 263-274.
188. Katsikis, P.D., Chu, C.Q., Brennan, F.M., Maini, R.N. and Feldmann, M. (1994) J. Exp. Med., 179, 1517-1527.
189. Walmsley, M., Katsikis, P.D., Abney, E., Parry, S., Williams, R.O., Maini, R.N. and Feldmann, M. (1996) Arthitis Rheum., 39, 495-503.
190. Williams, L.M., Sarma, U., Willets, K., Smallie, T., Brennan, F. and Foxwell, B.M. (2007) J. Biol. Chem., 282, 6965-6975.
191. Lemke, G. and Rothlin, C.V. (2008) Nat Rev. Immunol., 8, 327-336.
192. Sasaki, T., Knyazev, P.G., Clout, N.J., Cheburkin, Y., Gohring, W., Ullrich, A., Timpl, R. and Hohenester, E. (2006) EMBO J., 25, 80-87.
193. Stitt, T.N., Conn, G., Gore M., Lai, C., Bruno, J., Radziejewski, C., Mattsson, K., Fisher, J., Gies, D.R., Jones, P.F. and et al. (1995) Cell, 80, 661-670.
194. Camenisch, T.D., Koller, B.H., Earp, H.S. and Matsushima, G.K. (1999) J. Immunol., 162, 3498-3503.
195. Lu, Q. and Lemke, G. (2001) Science, 293, 306-311.
196. Rothlin, C.V., Ghosh, S., Zuniga, E.I., Oldstone, M.B. and Lemke, G. (2007) Cell, 131, 1124-1136.