메뉴 건너뛰기




Volumn 112, Issue 22, 1999, Pages 4067-4078

Impaired integrin-mediated signal transduction, altered cytoskeletal structure and reduced motility in Hck/Fgr deficient macrophages

Author keywords

Cell motility; Integrin signaling; Src family tyrosine kinase

Indexed keywords

ACTIN; COLLAGEN; CORTACTIN; FIBRONECTIN; FOCAL ADHESION KINASE; INTEGRIN; PAXILLIN; PROTEIN TYROSINE KINASE; TALIN; VITRONECTIN;

EID: 0033490109     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (137)

References (77)
  • 1
    • 0030947860 scopus 로고    scopus 로고
    • Substrate recognition by osteoclast precursors induces C-Src/microtubule association
    • Abu-Amer, Y., Ross, F. P., Schlesinger, P., Tondravi, M. M. and Teitelbaum, S. L. (1997). Substrate recognition by osteoclast precursors induces C-Src/microtubule association. J. Cell Biol. 137, 247-258.
    • (1997) J. Cell Biol. , vol.137 , pp. 247-258
    • Abu-Amer, Y.1    Ross, F.P.2    Schlesinger, P.3    Tondravi, M.M.4    Teitelbaum, S.L.5
  • 2
    • 0032476646 scopus 로고    scopus 로고
    • Impaired integrin-mediated adhesion and signaling in fibroblasts expressing a dominant-negative mutant PTP1B
    • Arregui, C. O., Balsamo, J. and Lilien, J. (1998). Impaired integrin-mediated adhesion and signaling in fibroblasts expressing a dominant-negative mutant PTP1B. J. Cell Biol. 143, 861-873.
    • (1998) J. Cell Biol. , vol.143 , pp. 861-873
    • Arregui, C.O.1    Balsamo, J.2    Lilien, J.3
  • 3
    • 0031050451 scopus 로고    scopus 로고
    • Cell anchorage and the cytoskeleton as partners in growth factor dependent cell cycle progression
    • Assoian, R. K. and Zhu, X. (1997). Cell anchorage and the cytoskeleton as partners in growth factor dependent cell cycle progression. Curr. Opin. Cell. Biol. 9, 93-98.
    • (1997) Curr. Opin. Cell. Biol. , vol.9 , pp. 93-98
    • Assoian, R.K.1    Zhu, X.2
  • 5
    • 0028167979 scopus 로고
    • β2 integrin-dependent protein tyrosine phosphorylation and activation of the FGR protein tyrosine kinase in human neutrophils
    • Berton, G., Fumagalli, L., Laudanna, C. and Sorio, C. (1994). β2 integrin-dependent protein tyrosine phosphorylation and activation of the FGR protein tyrosine kinase in human neutrophils. J. Cell Biol. 126, 1111-1121.
    • (1994) J. Cell Biol. , vol.126 , pp. 1111-1121
    • Berton, G.1    Fumagalli, L.2    Laudanna, C.3    Sorio, C.4
  • 6
    • 0030475975 scopus 로고    scopus 로고
    • Neutrophil activation by adhesion: Mechanisms and pathophysiological implications
    • Berton, G., Yan, S. R., Fumagalli, I., and Lowell, C. A. (1996). Neutrophil activation by adhesion: mechanisms and pathophysiological implications. Int. J. Clin. Lab. Res. 26, 160-177.
    • (1996) Int. J. Clin. Lab. Res. , vol.26 , pp. 160-177
    • Berton, G.1    Yan, S.R.2    Fumagalli, I.3    Lowell, C.A.4
  • 7
    • 0026342111 scopus 로고
    • Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversity
    • Butcher, E. C. (1991). Leukocyte-endothelial cell recognition: three (or more) steps to specificity and diversity. Cell 67, 1033-1036.
    • (1991) Cell , vol.67 , pp. 1033-1036
    • Butcher, E.C.1
  • 8
    • 0028216232 scopus 로고
    • Differential expression of ZAP-70 and Syk protein tyrosine kinases, and the role of this family of protein tyrosine kinases in TCR signaling
    • Chan, A. C., van Oers, N. S., Tran, A., Turka, L., Law, C. L., Ryan, J. C., Clark, E. A. and Weiss, A. (1994). Differential expression of ZAP-70 and Syk protein tyrosine kinases, and the role of this family of protein tyrosine kinases in TCR signaling. J. Immunol. 152, 4758-4766.
    • (1994) J. Immunol. , vol.152 , pp. 4758-4766
    • Chan, A.C.1    Van Oers, N.S.2    Tran, A.3    Turka, L.4    Law, C.L.5    Ryan, J.C.6    Clark, E.A.7    Weiss, A.8
  • 9
    • 0027273886 scopus 로고
    • Expression of a gene encoding a unique protein-tyrosine kinase within specific fetal-and adult-derived hematopoietic lineages
    • Choi, K., Kennedy, M. and Keller, G. (1993). Expression of a gene encoding a unique protein-tyrosine kinase within specific fetal-and adult-derived hematopoietic lineages. Proc. Nat. Acad. Sci. USA 90, 5747-5751.
    • (1993) Proc. Nat. Acad. Sci. USA , vol.90 , pp. 5747-5751
    • Choi, K.1    Kennedy, M.2    Keller, G.3
  • 10
    • 0027145638 scopus 로고
    • VLA-4 integrin can mediate CD11/CD18-independent transendothelial migration of human monocytes
    • Chuluyan, H. E. and Issekutz, A. C. (1993). VLA-4 integrin can mediate CD11/CD18-independent transendothelial migration of human monocytes. J. Clin. Invest. 92, 2768-2777.
    • (1993) J. Clin. Invest. , vol.92 , pp. 2768-2777
    • Chuluyan, H.E.1    Issekutz, A.C.2
  • 11
    • 0029121139 scopus 로고
    • IL-1 activation of endothelium supports VLA-4 (CD49d/CD29)-mediated monocyte transendothelial migration to C5a, MIP-1 alpha, RANTES, and PAF but inhibits migration to MCP-1: A regulatory role for endothelium-derived MCP-1
    • Chuluyan, H. E., Schall, T. J., Yoshimura, T. and Issekutz, A. C. (1995). IL-1 activation of endothelium supports VLA-4 (CD49d/CD29)-mediated monocyte transendothelial migration to C5a, MIP-1 alpha, RANTES, and PAF but inhibits migration to MCP-1: a regulatory role for endothelium-derived MCP-1. J. Leukoc. Biol. 58, 71-79.
    • (1995) J. Leukoc. Biol. , vol.58 , pp. 71-79
    • Chuluyan, H.E.1    Schall, T.J.2    Yoshimura, T.3    Issekutz, A.C.4
  • 12
    • 0028987936 scopus 로고
    • Integrins and signal transduction pathways: The road taken
    • Clark, E. A. and Brugge, J. S. (1995). Integrins and signal transduction pathways: the road taken. Science 268, 233-239.
    • (1995) Science , vol.268 , pp. 233-239
    • Clark, E.A.1    Brugge, J.S.2
  • 14
    • 0026938957 scopus 로고
    • Signal transduction by integrin receptors for extracellular matrix: Cooperative processing of extracellular information
    • Damsky, C. H. and Werb, Z. (1992). Signal transduction by integrin receptors for extracellular matrix: cooperative processing of extracellular information. Curr. Opin. Cell Biol. 4, 772-781.
    • (1992) Curr. Opin. Cell Biol. , vol.4 , pp. 772-781
    • Damsky, C.H.1    Werb, Z.2
  • 15
    • 0027528614 scopus 로고
    • Granulocyte-macrophage and macrophage colony-stimulating factors differentially regulate αv integrin expression on cultured human macrophages
    • De Nichilo, M. O. and Burns, G. F. (1993). Granulocyte-macrophage and macrophage colony-stimulating factors differentially regulate αv integrin expression on cultured human macrophages. Proc. Nat. Acd. Sci. USA 90, 2517-2521.
    • (1993) Proc. Nat. Acd. Sci. USA , vol.90 , pp. 2517-2521
    • De Nichilo, M.O.1    Burns, G.F.2
  • 16
    • 0029976232 scopus 로고    scopus 로고
    • Integrin αvβ5-dependent serine phosphorylation of paxillin in cultured human macrophages adherent to vitronectin
    • De Nichilo, M. O. and Yamada, K. M. (1996). Integrin αvβ5-dependent serine phosphorylation of paxillin in cultured human macrophages adherent to vitronectin. J. Biol. Chem. 271, 11016-11022.
    • (1996) J. Biol. Chem. , vol.271 , pp. 11016-11022
    • De Nichilo, M.O.1    Yamada, K.M.2
  • 17
    • 0032168740 scopus 로고    scopus 로고
    • PYK2 in osteoclasts is an adhesion kinase, localized in the sealing zone, activated by ligation of alpha(v)beta3 integrin, and phosphorylated by src kinase
    • Duong, L. T., Lakkakorpi, P. T., Nakamura, I., Machwate, M., Nagy, R. M. and Rodan, G. A. (1998). PYK2 in osteoclasts is an adhesion kinase, localized in the sealing zone, activated by ligation of alpha(v)beta3 integrin, and phosphorylated by src kinase. J. Clin. Invest. 102, 881-892.
    • (1998) J. Clin. Invest. , vol.102 , pp. 881-892
    • Duong, L.T.1    Lakkakorpi, P.T.2    Nakamura, I.3    Machwate, M.4    Nagy, R.M.5    Rodan, G.A.6
  • 18
    • 0018885287 scopus 로고
    • A 48-well micro chemotaxis assembly for rapid and accurate measurement of leukocyte migration
    • Falk, W., Goodwin, R. H., Jr. and Leonard, E. J. (1980). A 48-well micro chemotaxis assembly for rapid and accurate measurement of leukocyte migration. J. Immunol. Meth. 33, 239-247.
    • (1980) J. Immunol. Meth. , vol.33 , pp. 239-247
    • Falk, W.1    Goodwin R.H., Jr.2    Leonard, E.J.3
  • 19
    • 0027212363 scopus 로고
    • Integrin regulation of leukocyte inflammatory functions. CD11b/CD18 enhancement of the tumor necrosis factor-alpha responses of monocytes
    • Fan, S. T. and Edgington, T. S. (1993). Integrin regulation of leukocyte inflammatory functions. CD11b/CD18 enhancement of the tumor necrosis factor-alpha responses of monocytes. J. Immunol. 150, 2972-2980.
    • (1993) J. Immunol. , vol.150 , pp. 2972-2980
    • Fan, S.T.1    Edgington, T.S.2
  • 20
    • 0027253455 scopus 로고
    • Stimulation of protein tyrosine phosphorylation in human B cells after ligation of the β1 integrin VLA-4
    • Freedman, A. S., Rhynhart, K., Nojima, Y., Svahn, J., Eliseo, L., Benjamin, C. D., Morimoto, C. and Vivier, E. (1993) Stimulation of protein tyrosine phosphorylation in human B cells after ligation of the β1 integrin VLA-4. J. Immunol. 150, 1645-1652.
    • (1993) J. Immunol. , vol.150 , pp. 1645-1652
    • Freedman, A.S.1    Rhynhart, K.2    Nojima, Y.3    Svahn, J.4    Eliseo, L.5    Benjamin, C.D.6    Morimoto, C.7    Vivier, E.8
  • 21
    • 0027455465 scopus 로고
    • Adhesion-dependent protein tyrosine phosphorylation in neutrophils treated with tumor necrosis factor
    • Fuortes, M., Jin, W. W. and Nathan, C. (1993). Adhesion-dependent protein tyrosine phosphorylation in neutrophils treated with tumor necrosis factor. J. Cell Biol. 120, 777-784.
    • (1993) J. Cell Biol. , vol.120 , pp. 777-784
    • Fuortes, M.1    Jin, W.W.2    Nathan, C.3
  • 22
    • 0027076709 scopus 로고
    • An improved procedure for the purification of protein fused with glutathione S-transferase
    • Grieco, F., Hay, J. M. and Hull, R. (1992). An improved procedure for the purification of protein fused with glutathione S-transferase. BioTechniques 13, 856-858.
    • (1992) BioTechniques , vol.13 , pp. 856-858
    • Grieco, F.1    Hay, J.M.2    Hull, R.3
  • 24
    • 0033610844 scopus 로고    scopus 로고
    • Protein-tyrosine phosphatase alpha regulates Src family kinases and alters cell-substratum adhesion
    • Harder, K. W., Moller, N. P., Peacock, J. W. and Jirik, F. R. (1998). Protein-tyrosine phosphatase alpha regulates Src family kinases and alters cell-substratum adhesion. J. Biol. Chem. 273, 31890-31900.
    • (1998) J. Biol. Chem. , vol.273 , pp. 31890-31900
    • Harder, K.W.1    Moller, N.P.2    Peacock, J.W.3    Jirik, F.R.4
  • 25
    • 0003448569 scopus 로고
    • Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press
    • Harlow, E. and Lane, D. (1988). Antibodies: A Laboratory Manual. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press.
    • (1988) Antibodies: A Laboratory Manual
    • Harlow, E.1    Lane, D.2
  • 27
    • 0032525199 scopus 로고    scopus 로고
    • The related adhesion focal tyrosine kinase (RAFTK) is tyrosine phosphorylated and participates in colony-stimulating factor-1/macrophage colony-stimulating factor signaling in monocyte-macrophages
    • Hatch, W. C., Ganju, R. K., Hiregowdara, D., Avraham, S. and Groopman, J. E. (1998). The related adhesion focal tyrosine kinase (RAFTK) is tyrosine phosphorylated and participates in colony-stimulating factor-1/macrophage colony-stimulating factor signaling in monocyte-macrophages. Blood 91, 3967-3973.
    • (1998) Blood , vol.91 , pp. 3967-3973
    • Hatch, W.C.1    Ganju, R.K.2    Hiregowdara, D.3    Avraham, S.4    Groopman, J.E.5
  • 28
    • 0026770377 scopus 로고
    • Integrins: Versatility, modulation, and signaling in cell adhesion
    • Hynes, R. O. (1992). Integrins: versatility, modulation, and signaling in cell adhesion. Cell 69, 11-25.
    • (1992) Cell , vol.69 , pp. 11-25
    • Hynes, R.O.1
  • 30
    • 0030069382 scopus 로고    scopus 로고
    • Impairment of mobility in endodermal cells by FAK deficiency
    • Ilic, D., Kanazawa, S., Furuta, Y., Yamamoto, T. and Aizawa, S. (1996). Impairment of mobility in endodermal cells by FAK deficiency. Exp. Cell. Res. 222, 298-303.
    • (1996) Exp. Cell. Res. , vol.222 , pp. 298-303
    • Ilic, D.1    Kanazawa, S.2    Furuta, Y.3    Yamamoto, T.4    Aizawa, S.5
  • 31
    • 0029061303 scopus 로고
    • In vivo blood monocyte migration to acute inflammatory reactions. IL-1α, TNF-α. IFN-γ, and C5a utilizes LFA-1, Mac-1, and VLA-4. The relative importance of each integrin
    • Issekutz, T. B. (1995). In vivo blood monocyte migration to acute inflammatory reactions. IL-1α, TNF-α. IFN-γ, and C5a utilizes LFA-1, Mac-1, and VLA-4. The relative importance of each integrin. J. Immunol. 154, 6533-6540.
    • (1995) J. Immunol. , vol.154 , pp. 6533-6540
    • Issekutz, T.B.1
  • 32
    • 0027459771 scopus 로고
    • Signal transduction from the extracellular matrix
    • Juliano, R. L. and Haskill, S. (1993). Signal transduction from the extracellular matrix. J. Cell Biol. 120, 577-585.
    • (1993) J. Cell Biol. , vol.120 , pp. 577-585
    • Juliano, R.L.1    Haskill, S.2
  • 34
    • 0033522510 scopus 로고    scopus 로고
    • Src family kinases are required for integrin but not PDGFR signal transduction
    • Klinghoffer, R. A., Sachsenmaier, C., Cooper, J. A. and Soriano, P. (1999). Src family kinases are required for integrin but not PDGFR signal transduction. EMBO J. 18, 2459-2471.
    • (1999) EMBO J. , vol.18 , pp. 2459-2471
    • Klinghoffer, R.A.1    Sachsenmaier, C.2    Cooper, J.A.3    Soriano, P.4
  • 35
    • 0025946283 scopus 로고
    • Signal transduction by integrins: Increased protein tyrosine phosphorylation caused by clustering of β1 integrins
    • Kornberg, L. J., Earp, H. S., Turner, C. E., Prockop, C. and Juliano, R. L. (1991). Signal transduction by integrins: increased protein tyrosine phosphorylation caused by clustering of β1 integrins. Proc. Nat. Acad. Sci. USA 88, 8392-8396.
    • (1991) Proc. Nat. Acad. Sci. USA , vol.88 , pp. 8392-8396
    • Kornberg, L.J.1    Earp, H.S.2    Turner, C.E.3    Prockop, C.4    Juliano, R.L.5
  • 36
    • 17344362877 scopus 로고    scopus 로고
    • Signaling by integrin receptors
    • Kumar, C. C. (1998). Signaling by integrin receptors. Oncogene 17, 1365-1373.
    • (1998) Oncogene , vol.17 , pp. 1365-1373
    • Kumar, C.C.1
  • 37
    • 0029973887 scopus 로고    scopus 로고
    • Integrin-dependent signal transduction
    • Lafrenie, R. M. and Yamada, K. M. (1996). Integrin-dependent signal transduction. J. Cell. Biochem. 61, 543-553.
    • (1996) J. Cell. Biochem. , vol.61 , pp. 543-553
    • Lafrenie, R.M.1    Yamada, K.M.2
  • 38
    • 0029978533 scopus 로고    scopus 로고
    • Characterization of RAFTK, a novel focal adhesion kinase, and its integrin-dependent phosphorylation and activation in megakaryocytes
    • Li, J., Avraham, H., Rogers, R. A., Raja, S. and Avraham, S. (1996). Characterization of RAFTK, a novel focal adhesion kinase, and its integrin-dependent phosphorylation and activation in megakaryocytes. Blood 88, 417-428.
    • (1996) Blood , vol.88 , pp. 417-428
    • Li, J.1    Avraham, H.2    Rogers, R.A.3    Raja, S.4    Avraham, S.5
  • 39
    • 0033605594 scopus 로고    scopus 로고
    • Interactions between two cytoskeleton-associated tyrosine kinases: Calcium-dependent tyrosine kinase and focal adhesion tyrosine kinase
    • Li, X., Dy, R. C., Cance, W. G., Graves, L. M. and Earp, H. S. (1999). Interactions between two cytoskeleton-associated tyrosine kinases: calcium-dependent tyrosine kinase and focal adhesion tyrosine kinase. J. Biol. Chem. 274, 8917-8924.
    • (1999) J. Biol. Chem. , vol.274 , pp. 8917-8924
    • Li, X.1    Dy, R.C.2    Cance, W.G.3    Graves, L.M.4    Earp, H.S.5
  • 40
    • 0018376872 scopus 로고
    • Secretion of plasminogen activator by bone marrow-derived mononuclear phagocytes and its enhancement by colony-stimulating factor
    • Lin, H. S. and Gordon, S. (1979). Secretion of plasminogen activator by bone marrow-derived mononuclear phagocytes and its enhancement by colony-stimulating factor. J. Exp. Med. 150, 231-245.
    • (1979) J. Exp. Med. , vol.150 , pp. 231-245
    • Lin, H.S.1    Gordon, S.2
  • 41
    • 0028030408 scopus 로고
    • The role of protein tyrosine phosphorylation in integrin-mediated gene induction in monocytes
    • Lin, T. H., Yurochko, A., Kornberg, L., Morris, J., Walker, J. J., Haskill, S. and Juliano, R. L. (1994). The role of protein tyrosine phosphorylation in integrin-mediated gene induction in monocytes. J. Cell Biol. 126, 1585-1593.
    • (1994) J. Cell Biol. , vol.126 , pp. 1585-1593
    • Lin, T.H.1    Yurochko, A.2    Kornberg, L.3    Morris, J.4    Walker, J.J.5    Haskill, S.6    Juliano, R.L.7
  • 42
    • 0029005762 scopus 로고
    • Integrin-mediated tyrosine phosphorylation and cytokine message induction in monocytic cells. A possible signaling role for the Syk tyrosine kinase
    • Lin, T. H., Rosales, C., Mondal, K., Bolen, J. B., Haskill, S. and Juliano, R. L. (1995). Integrin-mediated tyrosine phosphorylation and cytokine message induction in monocytic cells. A possible signaling role for the Syk tyrosine kinase. J. Biol. Chem. 270, 16189-16197.
    • (1995) J. Biol. Chem. , vol.270 , pp. 16189-16197
    • Lin, T.H.1    Rosales, C.2    Mondal, K.3    Bolen, J.B.4    Haskill, S.5    Juliano, R.L.6
  • 43
    • 0028293147 scopus 로고
    • Functional overlap in the src gene family: Inactivation of hck and fgr impairs natural immunity
    • Lowell, C. A., Soriano, P. and Varmus, H. E. (1994). Functional overlap in the src gene family: inactivation of hck and fgr impairs natural immunity. Genes De. 8, 387-398.
    • (1994) Genes De. , vol.8 , pp. 387-398
    • Lowell, C.A.1    Soriano, P.2    Varmus, H.E.3
  • 44
    • 0030008394 scopus 로고    scopus 로고
    • c-fgr results in defective adhesion-dependent neutrophil functions
    • c-fgr results in defective adhesion-dependent neutrophil functions. J. Cell Biol. 133, 895-910.
    • (1996) J. Cell Biol. , vol.133 , pp. 895-910
    • Lowell, C.A.1    Fumagalli, L.2    Berton, G.3
  • 45
    • 0032560544 scopus 로고    scopus 로고
    • Resistance to endotoxic shock and reduced neutrophil migration in mice deficient for the Src-family kinases Hck and Fgr
    • Lowell, C. A. and Berton, G. (1998). Resistance to endotoxic shock and reduced neutrophil migration in mice deficient for the Src-family kinases Hck and Fgr. Proc. Nat. Acad. Sci. USA 95, 7580-7584.
    • (1998) Proc. Nat. Acad. Sci. USA , vol.95 , pp. 7580-7584
    • Lowell, C.A.1    Berton, G.2
  • 46
    • 0030948463 scopus 로고    scopus 로고
    • VLA-4 integrin cross-linking on human monocytic THP-1 cells induces tissue factor expression by a mechanism involving mitogen-activated protein kinase
    • McGilvray, I. D., Lu, Z., Bitar, R., Dackiw, A. P. B., Davreux, C. J. and Rotstein, O. D. (1997). VLA-4 integrin cross-linking on human monocytic THP-1 cells induces tissue factor expression by a mechanism involving mitogen-activated protein kinase. J. Biol. Chem. 272, 10287-10294.
    • (1997) J. Biol. Chem. , vol.272 , pp. 10287-10294
    • McGilvray, I.D.1    Lu, Z.2    Bitar, R.3    Dackiw, A.P.B.4    Davreux, C.J.5    Rotstein, O.D.6
  • 47
    • 0028294140 scopus 로고
    • Monocytes use either CD11/CD18 or VLA-4 to migrate across human endothelium in vitro
    • Meerschaert, J. and Furie, M. B. (1994). Monocytes use either CD11/CD18 or VLA-4 to migrate across human endothelium in vitro. J. Immunol. 152, 1915-1926.
    • (1994) J. Immunol. , vol.152 , pp. 1915-1926
    • Meerschaert, J.1    Furie, M.B.2
  • 48
    • 14844362694 scopus 로고
    • The adhesion molecules used by monocytes for migration across endothelium include CD11a/CD18, CD11b/CD18, and VLA-4 on monocytes and ICAM-1, VCAM-1, and other ligands on endothelium
    • Meerschaert, J. and Furie, M. B. (1995). The adhesion molecules used by monocytes for migration across endothelium include CD11a/CD18, CD11b/CD18, and VLA-4 on monocytes and ICAM-1, VCAM-1, and other ligands on endothelium. J. Immunol. 154, 4099-4112.
    • (1995) J. Immunol. , vol.154 , pp. 4099-4112
    • Meerschaert, J.1    Furie, M.B.2
  • 49
    • 0030912071 scopus 로고    scopus 로고
    • Lipopolysaccharide (LPS)-induced macrophage activation and signal transduction in the absence of Src-family kinases Hck, Fgr, and Lyn
    • Meng, F. and Lowell, C. A. (1997). Lipopolysaccharide (LPS)-induced macrophage activation and signal transduction in the absence of Src-family kinases Hck, Fgr, and Lyn. J. Exp. Med. 185, 1661-1670.
    • (1997) J. Exp. Med. , vol.185 , pp. 1661-1670
    • Meng, F.1    Lowell, C.A.2
  • 51
    • 0033555864 scopus 로고    scopus 로고
    • Adhesion-dependent degranulation of neutrophils requires the Src-family kinases Fgr and Hck
    • Mocsai, A., Ligetiu, E., Lowell, C. A. and Berton, G. (1999). Adhesion-dependent degranulation of neutrophils requires the Src-family kinases Fgr and Hck. J. Immunol. 162, 1120-1126.
    • (1999) J. Immunol. , vol.162 , pp. 1120-1126
    • Mocsai, A.1    Ligetiu, E.2    Lowell, C.A.3    Berton, G.4
  • 52
    • 0030744134 scopus 로고    scopus 로고
    • Role of phosphatases in lymphocyte activation
    • Neel, B. G. (1997). Role of phosphatases in lymphocyte activation. Curr. Opin. Immunol. 9, 405-420.
    • (1997) Curr. Opin. Immunol. , vol.9 , pp. 405-420
    • Neel, B.G.1
  • 53
    • 0025283118 scopus 로고
    • Leukocyte adhesion to endothelium in inflammation
    • Osborn, L. (1990). Leukocyte adhesion to endothelium in inflammation. Cell 62, 3-6.
    • (1990) Cell , vol.62 , pp. 3-6
    • Osborn, L.1
  • 54
    • 0029965695 scopus 로고    scopus 로고
    • Integrin-mediated signalling: Regulation by protein tyrosine kinases and small GTP-binding proteins
    • Parsons, J. T. (1996). Integrin-mediated signalling: regulation by protein tyrosine kinases and small GTP-binding proteins. Curr. Opin. Cell Biol. 8, 146-152.
    • (1996) Curr. Opin. Cell Biol. , vol.8 , pp. 146-152
    • Parsons, J.T.1
  • 55
    • 0030898418 scopus 로고    scopus 로고
    • Src family protein tyrosine kinases: Cooperating with growth factor and adhesion signaling pathways
    • Parsons, J. T. and Parsons, S. J. (1997). Src family protein tyrosine kinases: cooperating with growth factor and adhesion signaling pathways. Curr Opin. Cell. Biol. 9, 187-192.
    • (1997) Curr Opin. Cell. Biol. , vol.9 , pp. 187-192
    • Parsons, J.T.1    Parsons, S.J.2
  • 56
    • 0030943398 scopus 로고    scopus 로고
    • T cell antigen receptor signal transduction
    • Qian, D. and Weiss, A. (1997). T cell antigen receptor signal transduction. Curr. Opin. Cell. Biol. 9, 205-212.
    • (1997) Curr. Opin. Cell. Biol. , vol.9 , pp. 205-212
    • Qian, D.1    Weiss, A.2
  • 57
    • 0029971297 scopus 로고    scopus 로고
    • A mechanism for regulation of the adhesion-associated protein tyrosine kinase pp125FAK
    • Richardson, A. and Parsons, T. (1996). A mechanism for regulation of the adhesion-associated protein tyrosine kinase pp125FAK. Nature 380, 538-540.
    • (1996) Nature , vol.380 , pp. 538-540
    • Richardson, A.1    Parsons, T.2
  • 58
    • 0031172246 scopus 로고    scopus 로고
    • CD45 regulates Src-family member kinase activity associated with macrophage integrin-mediated adhesion
    • Roach, T., Slater, S., Koval, M., White, L., McFarland, E. C., Okumura, M., Thomas, M. and Brown, E. (1997). CD45 regulates Src-family member kinase activity associated with macrophage integrin-mediated adhesion. Curr. Biol. 7, 408-417.
    • (1997) Curr. Biol. , vol.7 , pp. 408-417
    • Roach, T.1    Slater, S.2    Koval, M.3    White, L.4    McFarland, E.C.5    Okumura, M.6    Thomas, M.7    Brown, E.8
  • 59
    • 0028331263 scopus 로고
    • Tyrosine kinase activity, cytoskeletal organization, and motility in human vascular endothelial cells
    • Romer, L. H., McLean, N., Turner, C. E. and Burridge, K. (1994). Tyrosine kinase activity, cytoskeletal organization, and motility in human vascular endothelial cells. Mol. Biol. Cell 5, 349-361.
    • (1994) Mol. Biol. Cell , vol.5 , pp. 349-361
    • Romer, L.H.1    McLean, N.2    Turner, C.E.3    Burridge, K.4
  • 61
    • 0028122650 scopus 로고
    • Focal adhesion kinase and associated proteins
    • Schaller, M. D. and Parsons, J. T. (1994). Focal adhesion kinase and associated proteins. Curr. Opin. Cell. Biol. 6, 705-710.
    • (1994) Curr. Opin. Cell. Biol. , vol.6 , pp. 705-710
    • Schaller, M.D.1    Parsons, J.T.2
  • 62
    • 0028609382 scopus 로고
    • Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase
    • Schlaepfer, D. D., Hanks, S. K., Hunter, T. and van der Geer, P. (1994). Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase. Nature 372, 786-791.
    • (1994) Nature , vol.372 , pp. 786-791
    • Schlaepfer, D.D.1    Hanks, S.K.2    Hunter, T.3    Van Der Geer, P.4
  • 65
    • 0025155349 scopus 로고
    • Adherence-dependent increase in human monocyte PDGF(B) mRNA is associated with increases in c-fos, c-jun, and EGR2 mRNA
    • Shaw, R. J., Doherty, D. E., Ritter, A. G., Benedict, S. H. and Clark, R. A. (1990). Adherence-dependent increase in human monocyte PDGF(B) mRNA is associated with increases in c-fos, c-jun, and EGR2 mRNA. J. Cell Biol. 111, 2139-2148.
    • (1990) J. Cell Biol. , vol.111 , pp. 2139-2148
    • Shaw, R.J.1    Doherty, D.E.2    Ritter, A.G.3    Benedict, S.H.4    Clark, R.A.5
  • 66
    • 0032531732 scopus 로고    scopus 로고
    • Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK-cell migration
    • Sieg, D. J., Ilic, D., Jones, K. C., Damsky, C. H., Hunter, T. and Schlaepfer, D. D. (1998). Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK-cell migration. EMBO J. 17, 5933-5947.
    • (1998) EMBO J. , vol.17 , pp. 5933-5947
    • Sieg, D.J.1    Ilic, D.2    Jones, K.C.3    Damsky, C.H.4    Hunter, T.5    Schlaepfer, D.D.6
  • 67
    • 0032494080 scopus 로고    scopus 로고
    • ZAP-70 tyrosine kinase is required for LFA-1-dependent T cell migration
    • Soede, R. D., Wijnands, Y. M., Van Kouteren-Cobzaru, I. and Roos, E. (1998). ZAP-70 tyrosine kinase is required for LFA-1-dependent T cell migration. J. Cell Biol. 142, 1371-1379.
    • (1998) J. Cell Biol. , vol.142 , pp. 1371-1379
    • Soede, R.D.1    Wijnands, Y.M.2    Van Kouteren-Cobzaru, I.3    Roos, E.4
  • 68
    • 0032486198 scopus 로고    scopus 로고
    • Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN
    • Tamura, M., Gu, J., Matsumoto, K., Aota, S., Parsons, R. and Yamada, K. M. (1998). Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN. Science 280, 1614-1617.
    • (1998) Science , vol.280 , pp. 1614-1617
    • Tamura, M.1    Gu, J.2    Matsumoto, K.3    Aota, S.4    Parsons, R.5    Yamada, K.M.6
  • 69
    • 0027716791 scopus 로고
    • The Src family of tyrosine protein kinases in hemopoietic signal transduction
    • Tsygankov, A. and Bolen, J. (1993). The Src family of tyrosine protein kinases in hemopoietic signal transduction. Stem Cells 11, 371-380.
    • (1993) Stem Cells , vol.11 , pp. 371-380
    • Tsygankov, A.1    Bolen, J.2
  • 70
    • 0029664531 scopus 로고    scopus 로고
    • cas signaling complex formation upon integrin-mediated cell adhesion: A role for Src family kinases
    • cas signaling complex formation upon integrin-mediated cell adhesion: a role for Src family kinases. Mol. Cell. Biol. 16, 2606-2613.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 2606-2613
    • Vuori, K.1    Hirai, H.2    Aizawa, S.3    Ruoslahti, E.4
  • 71
    • 0028981376 scopus 로고
    • Tyrosine phosphorylation of p130Cas and cortactin accompanies integrin-mediated cell adhesion to extracellular matrix
    • Vuori, K. and Ruoslahti, E. (1995). Tyrosine phosphorylation of p130Cas and cortactin accompanies integrin-mediated cell adhesion to extracellular matrix. J. Biol Chem. 270, 22259-22262.
    • (1995) J. Biol Chem. , vol.270 , pp. 22259-22262
    • Vuori, K.1    Ruoslahti, E.2
  • 72
    • 0029837596 scopus 로고    scopus 로고
    • Sequential regulation of α4β1 and α5β1 integrin avidity by CC chemokines in monocyles: Implications for transendothelial chemotaxis
    • Weber, C., Alon, R., Moser, B. and Springer, T. A. (1996). Sequential regulation of α4β1 and α5β1 integrin avidity by CC chemokines in monocyles: implications for transendothelial chemotaxis. J. Cell Biol. 134, 1063-1073.
    • (1996) J. Cell Biol. , vol.134 , pp. 1063-1073
    • Weber, C.1    Alon, R.2    Moser, B.3    Springer, T.A.4
  • 73
    • 0031050449 scopus 로고    scopus 로고
    • Molecular interactions in cell adhesion complexes
    • Yamada, K. M. and Geiger, B. (1997). Molecular interactions in cell adhesion complexes. Curr. Opin. Cell. Biol. 9, 76-85.
    • (1997) Curr. Opin. Cell. Biol. , vol.9 , pp. 76-85
    • Yamada, K.M.1    Geiger, B.2
  • 74
    • 0029414430 scopus 로고
    • lyn in adherent human neutrophils: Evidence for a role of divalent cations in regulating neutrophil adhesion and protein tyrosine kinase activities
    • lyn in adherent human neutrophils: evidence for a role of divalent cations in regulating neutrophil adhesion and protein tyrosine kinase activities. J. Inflamm. 45, 297-311.
    • (1995) J. Inflamm. , vol.45 , pp. 297-311
    • Yan, S.R.1    Fumagalli, L.2    Berton, G.3
  • 75
    • 0031568669 scopus 로고    scopus 로고
    • syk and Src family kinases in neutrophils spreading over fibrinogen
    • syk and Src family kinases in neutrophils spreading over fibrinogen. J. Immunol. 158, 1902-1910.
    • (1997) J. Immunol. , vol.158 , pp. 1902-1910
    • Yan, S.R.1    Huang, M.2    Berton, G.3
  • 76
    • 0027218590 scopus 로고
    • Leukocyte response integrin-and integrin-associated protein act as a signal transduction unit in generation of a phagocyte respiratory burst
    • Zhou, M. and Brown, E. J. (1993). Leukocyte response integrin-and integrin-associated protein act as a signal transduction unit in generation of a phagocyte respiratory burst. J. Exp. Med. 178, 1165-1174.
    • (1993) J. Exp. Med. , vol.178 , pp. 1165-1174
    • Zhou, M.1    Brown, E.J.2
  • 77
    • 0026499960 scopus 로고
    • Endothelial cell interactions with granulocytes: Tethering and signaling molecules
    • Zimmerman, G. A., Prescott, S. M. and McIntyre, T. M. (1992). Endothelial cell interactions with granulocytes: tethering and signaling molecules. Immunol. Today 13, 93-100.
    • (1992) Immunol. Today , vol.13 , pp. 93-100
    • Zimmerman, G.A.1    Prescott, S.M.2    McIntyre, T.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.