Critical role of the carboxyl terminus of proline-rich tyrosine kinase (Pyk2) in the activation of human neutrophils by tumor necrosis factor: Separation of signals for the respiratory burst and degranulation

Journal of Experimental Medicine

Volumn 197, Issue 1, 2003, Pages 63-75

  Han, Hyunsil ^a   Fuortes, Michele ^a   Nathan, Carl ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Neutrophil; Pyk2; Syk; Tat; TNF

Indexed keywords

FOCAL ADHESION KINASE 2; PROTEIN KINASE SYK; PROTEIN TYROSINE KINASE; TRANSACTIVATOR PROTEIN; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL SPREADING; CHEMICAL BINDING; CONTROLLED STUDY; CYTOKINE PRODUCTION; DEGRANULATION; ENZYME ACTIVATION; ENZYME MECHANISM; ENZYME PHOSPHORYLATION; ENZYME STRUCTURE; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; INFLAMMATION; INHIBITION KINETICS; LISTERIA; NEUTROPHIL; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; REGULATORY MECHANISM; RESPIRATORY BURST; SALMONELLA; SIGNAL TRANSDUCTION;

CELL ADHESION; CELL DEGRANULATION; CELL DIVISION; FLOW CYTOMETRY; FOCAL ADHESION KINASE 2; GENE PRODUCTS, TAT; HUMANS; LISTERIA MONOCYTOGENES; MUTATION; NEUTROPHIL ACTIVATION; NEUTROPHILS; PROLINE; PROTEIN STRUCTURE, TERTIARY; PROTEIN-TYROSINE KINASES; RECOMBINANT FUSION PROTEINS; RESPIRATORY BURST; SALMONELLA TYPHIMURIUM; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0037240676     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20021638     Document Type: Article

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