Steady state kinetics of spleen tyrosine kinase investigated by a real time fluorescence assay

Biochemistry

Volumn 46, Issue 51, 2007, Pages 15103-15114

  Papp, Eva ^a   Tse, Joyce K Y ^a   Ho, Angdung ^a   Wang, Sandra ^a   Shaw, David ^a   Lee, Simon ^a   Barnett, Jim ^a   Swinney, David C ^a   Bradshaw, J Michael ^a  

^a ROCHE BIOSCIENCE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLUORESCENCE ASSAYS; MUTANT LACKING TYROSINES; SPLEEN TYROSINE KINASE; SUBSTRATE PHOSPHORYLATION;

AMINO ACIDS; BINDING ENERGY; BIOASSAY; FLUORESCENCE; PHOSPHORYLATION; SUBSTRATES;

ENZYMES;

PROTEIN KINASE INHIBITOR; PROTEIN KINASE SYK; TYROSINE; TYRPHOSTIN; TYRPHOSTIN AG 538; UNCLASSIFIED DRUG; YM 193306;

ARTICLE; AUTOPHOSPHORYLATION; BINDING SITE; CATALYSIS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME MECHANISM; ENZYME REGULATION; ENZYME SUBSTRATE COMPLEX; ENZYMOLOGY; FLUORESCENCE; IMMUNOCOMPETENT CELL; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN DOMAIN; SIGNAL TRANSDUCTION; STEADY STATE;

ADENOSINE TRIPHOSPHATE; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; KINETICS; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; PEPTIDES; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PROTEIN-TYROSINE KINASES; SPECTROMETRY, FLUORESCENCE; SUBSTRATE SPECIFICITY; TIME FACTORS;

EID: 37349014505     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi701596u     Document Type: Article

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