The SRC family-selective tyrosine kinase inhibitor PP1 blocks LPS and IFN-γ-mediated TNF and iNOS production in murine macrophages

Shock

Volumn 12, Issue 5, 1999, Pages 350-354

  Orlicek, Shari L ^a,b,c,e   Hanke, Jeffrey H ^d   English, B Keith ^a,b  

^a LE BONHEUR CHILDREN'S MEDICAL CENTER   (United States)

^b UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^c ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^d PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

^e WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINO 5 (4 METHYLPHENYL) 7 (TERT BUTYL)PYRAZOLO(3,4 D)PYRIMIDINE; 4-AMINO-5-(4-METHYLPHENYL)-7-(TERT-BUTYL)PYRAZOLO(3,4-D)PYRIMIDINE; CELL CYCLE PROTEIN; ENZYME INHIBITOR; GAMMA INTERFERON; HCK PROTEIN, MOUSE; HEMATOPOIETIC CELL KINASE; INDUCIBLE NITRIC OXIDE SYNTHASE; JAK2 PROTEIN, MOUSE; JANUS KINASE 2; LIPOPOLYSACCHARIDE; NITRIC OXIDE SYNTHASE; NOS2 PROTEIN, MOUSE; ONCOPROTEIN; PROTEIN TYROSINE KINASE; PYRAZOLE DERIVATIVE; PYRIMIDINE DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA; TYROSINE; VAV PROTEIN; VAV1 PROTEIN, MOUSE;

ANIMAL; ARTICLE; BIOSYNTHESIS; CELL LINE; DRUG ANTAGONISM; DRUG EFFECT; MACROPHAGE; METABOLISM; MOUSE; PHOSPHORYLATION;

ANIMALS; CELL CYCLE PROTEINS; CELL LINE; ENZYME INHIBITORS; INTERFERON TYPE II; JANUS KINASE 2; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-HCK; PROTO-ONCOGENE PROTEINS C-VAV; PYRAZOLES; PYRIMIDINES; SRC-FAMILY KINASES; TUMOR NECROSIS FACTOR-ALPHA; TYROSINE;

EID: 0033228567     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/00024382-199911000-00004     Document Type: Article

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