메뉴 건너뛰기




Volumn 36, Issue 3-4, 2008, Pages 160-176

Tissue factor and cancer

Author keywords

Angiogenesis; Anti tissue factor therapy; Cancer; Coagulation; Oncogenes; Tissue factor

Indexed keywords

ANGIOGENESIS INHIBITOR; CANERTINIB; CETUXIMAB; HIRUDIN; LOW MOLECULAR WEIGHT HEPARIN; NONSTEROID ANTIINFLAMMATORY AGENT; RETINOIC ACID; THROMBOPLASTIN; ANTINEOPLASTIC AGENT; BLOOD CLOTTING FACTOR; TUMOR PROTEIN;

EID: 61449255591     PISSN: 14248832     EISSN: None     Source Type: Journal    
DOI: 10.1159/000175154     Document Type: Review
Times cited : (53)

References (279)
  • 1
    • 0024600974 scopus 로고
    • Complete sequence of the human tissue factor gene, a highly regulated cellular receptor that initiates the coagulation protease cascade
    • Mackman N, Morrissey JH, Fowler B, Edgington TS: Complete sequence of the human tissue factor gene, a highly regulated cellular receptor that initiates the coagulation protease cascade. Biochemistry 1989;28:1755-1762.
    • (1989) Biochemistry , vol.28 , pp. 1755-1762
    • Mackman, N.1    Morrissey, J.H.2    Fowler, B.3    Edgington, T.S.4
  • 3
    • 0034917278 scopus 로고    scopus 로고
    • Tissue factor: An enzyme co-factor and a true receptor
    • Morrissey JH: Tissue factor: an enzyme co-factor and a true receptor. Thromb Haemost 2001;86:66-74.
    • (2001) Thromb Haemost , vol.86 , pp. 66-74
    • Morrissey, J.H.1
  • 4
    • 0036341469 scopus 로고    scopus 로고
    • Tissue factor and angiogenesis in cancer
    • Fernandez PM, Rickles FR: Tissue factor and angiogenesis in cancer. Curr Opin Hematol 2002;9: 401-406.
    • (2002) Curr Opin Hematol , vol.9 , pp. 401-406
    • Fernandez, P.M.1    Rickles, F.R.2
  • 6
    • 68249161350 scopus 로고    scopus 로고
    • Tissue-specific hemostasis: Role of tissue factor
    • Mackman N: Tissue-specific hemostasis: role of tissue factor. J Thromb Haemost 2007.
    • (2007) J Thromb Haemost
    • Mackman, N.1
  • 8
    • 0034648757 scopus 로고    scopus 로고
    • Thrombin signalling and protease-activated receptors
    • Coughlin SR: Thrombin signalling and protease-activated receptors. Nature 2000;407: 258-264.
    • (2000) Nature , vol.407 , pp. 258-264
    • Coughlin, S.R.1
  • 9
    • 4544254453 scopus 로고    scopus 로고
    • Role of tissue factor in haemostasis, thrombosis, angiogenesis and inflammation: Lessons from low tissue factor mice
    • Pawlinski R, Pedersen B, Erlich J, Mackman N: Role of tissue factor in haemostasis, thrombosis, angiogenesis and inflammation: lessons from low tissue factor mice. Thromb Haemost 2004;92: 444-450.
    • (2004) Thromb Haemost , vol.92 , pp. 444-450
    • Pawlinski, R.1    Pedersen, B.2    Erlich, J.3    Mackman, N.4
  • 10
    • 1642279517 scopus 로고    scopus 로고
    • Protease-activated receptors: Contribution to physiology and disease
    • Ossovskaya VS, Bunnett NW: Protease-activated receptors: contribution to physiology and disease. Physiol Rev 2004;84: 579-621.
    • (2004) Physiol Rev , vol.84 , pp. 579-621
    • Ossovskaya, V.S.1    Bunnett, N.W.2
  • 11
    • 23244432180 scopus 로고    scopus 로고
    • Signaling of the tissue factor coagulation pathway in angiogenesis and cancer
    • Belting M, Ahamed J, Ruf W: Signaling of the tissue factor coagulation pathway in angiogenesis and cancer. Arterioscler Thromb Vasc Biol 2005;25:1545-1550.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 1545-1550
    • Belting, M.1    Ahamed, J.2    Ruf, W.3
  • 12
    • 0034608013 scopus 로고    scopus 로고
    • Thrombin responses in human endothelial cells. Contributions from receptors other than PAR1 include the transactivation of PAR2 by thrombin-cleaved PAR1
    • O'Brien PJ, Prevost N, Molino M, Hollinger MK, Woolkalis MJ, Woulfe DS, Brass LF: Thrombin responses in human endothelial cells. Contributions from receptors other than PAR1 include the transactivation of PAR2 by thrombin-cleaved PAR1. J Biol Chem 2000;275:13502-13509.
    • (2000) J Biol Chem , vol.275 , pp. 13502-13509
    • O'Brien, P.J.1    Prevost, N.2    Molino, M.3    Hollinger, M.K.4    Woolkalis, M.J.5    Woulfe, D.S.6    Brass, L.F.7
  • 13
    • 0345359895 scopus 로고    scopus 로고
    • Tissue factor-dependent signaling in tumor biology
    • Ruf W: Tissue factor-dependent signaling in tumor biology. Pathophysiol Haemost Thromb 2003;33(suppl 1):28-30.
    • (2003) Pathophysiol Haemost Thromb , vol.33 , Issue.SUPPL. 1 , pp. 28-30
    • Ruf, W.1
  • 14
    • 33750616197 scopus 로고    scopus 로고
    • Thrombin induces tumor growth, metastasis, and an-giogenesis: Evidence for a thrombin-regulated dormant tumor phenotype
    • Nierodzik ML, Karpatkin S: Thrombin induces tumor growth, metastasis, and an-giogenesis: evidence for a thrombin-regulated dormant tumor phenotype. Cancer Cell 2006;10:355-362.
    • (2006) Cancer Cell , vol.10 , pp. 355-362
    • Nierodzik, M.L.1    Karpatkin, S.2
  • 15
    • 34447624141 scopus 로고    scopus 로고
    • Pawlinski R, Tencati M, Holscher T, Pedersen B, Voet T, Tilley RE, Marynen P, Mackman N: Role of cardiac myocyte tissue factor in heart hemostasis. J Thromb Haemost 2007;5: 16 9 3-17 0 0 .
    • Pawlinski R, Tencati M, Holscher T, Pedersen B, Voet T, Tilley RE, Marynen P, Mackman N: Role of cardiac myocyte tissue factor in heart hemostasis. J Thromb Haemost 2007;5: 16 9 3-17 0 0 .
  • 16
    • 0032498848 scopus 로고    scopus 로고
    • A role for tissue factor in cell adhesion and migration mediated by interaction with actin-binding protein 280
    • Ott I, Fischer EG, Miyagi Y, Mueller BM, Ruf W: A role for tissue factor in cell adhesion and migration mediated by interaction with actin-binding protein 280. J Cell Biol 1998;14 0 : 1241-1253.
    • (1998) J Cell Biol , vol.14 , Issue.0 , pp. 1241-1253
    • Ott, I.1    Fischer, E.G.2    Miyagi, Y.3    Mueller, B.M.4    Ruf, W.5
  • 19
    • 0034640499 scopus 로고    scopus 로고
    • Pendurthi UR, Allen KE, Ezban M, Rao LV: Factor VIIa and thrombin induce the expression of Cyr61 and connective tissue growth factor, extracellular matrix signaling proteins that could act as possible downstream mediators in factor VIIa ! tissue factor-induced signal transduction. J Biol Chem 2000;275: 14 63 2-14 6 41.
    • Pendurthi UR, Allen KE, Ezban M, Rao LV: Factor VIIa and thrombin induce the expression of Cyr61 and connective tissue growth factor, extracellular matrix signaling proteins that could act as possible downstream mediators in factor VIIa ! tissue factor-induced signal transduction. J Biol Chem 2000;275: 14 63 2-14 6 41.
  • 20
    • 0033044220 scopus 로고    scopus 로고
    • Cancer and blood coagulation: Molecular aspects
    • Bromberg ME, Cappello M: Cancer and blood coagulation: molecular aspects. Cancer J Sci Am 1999;5: 132-138 .
    • (1999) Cancer J Sci Am , vol.5 , pp. 132-138
    • Bromberg, M.E.1    Cappello, M.2
  • 21
    • 0034010134 scopus 로고    scopus 로고
    • Binding of factor VIIa to tissue factor on keratinocytes induces gene expression
    • Camerer E, Gjernes E, Wiiger M, Pringle S, Prydz H: Binding of factor VIIa to tissue factor on keratinocytes induces gene expression. J Biol Chem 2000;275: 6580-6585.
    • (2000) J Biol Chem , vol.275 , pp. 6580-6585
    • Camerer, E.1    Gjernes, E.2    Wiiger, M.3    Pringle, S.4    Prydz, H.5
  • 24
    • 0029794555 scopus 로고    scopus 로고
    • Targeted disruption of the murine tissue factor gene results in embryonic lethality
    • Toomey JR, Kratzer KE, Lasky NM, Stanton JJ, Broze GJ Jr: Targeted disruption of the murine tissue factor gene results in embryonic lethality. Blood 1996;88: 1583-1587.
    • (1996) Blood , vol.88 , pp. 1583-1587
    • Toomey, J.R.1    Kratzer, K.E.2    Lasky, N.M.3    Stanton, J.J.4    Broze Jr, G.J.5
  • 26
    • 0034045244 scopus 로고    scopus 로고
    • Mouse embryogenesis requires the tissue factor extracellular domain but not the cytoplasmic domain
    • Parry GC, Mackman N: Mouse embryogenesis requires the tissue factor extracellular domain but not the cytoplasmic domain. J Clin Invest 2000;105:1547-1554.
    • (2000) J Clin Invest , vol.105 , pp. 1547-1554
    • Parry, G.C.1    Mackman, N.2
  • 27
    • 0024382713 scopus 로고
    • Functional tissue factor is entirely cell surface expressed on lipopolysaccharide-stimulated human blood monocytes and a constitutively tissue factor-producing neoplastic cell line
    • Drake TA, Ruf W, Morrissey JH, Edging ton TS: Functional tissue factor is entirely cell surface expressed on lipopolysaccharide-stimulated human blood monocytes and a constitutively tissue factor-producing neoplastic cell line. J Cell Biol 1989;109:389-395.
    • (1989) J Cell Biol , vol.109 , pp. 389-395
    • Drake, T.A.1    Ruf, W.2    Morrissey, J.H.3    Edging ton, T.S.4
  • 28
    • 0025708079 scopus 로고
    • Localization of human tissue factor antigen by immunostaining with monospecific, polyclonal anti-human tissue factor antibody
    • Fleck RA, Rao LV, Rapaport SI, Varki N: Localization of human tissue factor antigen by immunostaining with monospecific, polyclonal anti-human tissue factor antibody. Thromb Res 1990;59:421-437.
    • (1990) Thromb Res , vol.59 , pp. 421-437
    • Fleck, R.A.1    Rao, L.V.2    Rapaport, S.I.3    Varki, N.4
  • 29
    • 0027732172 scopus 로고
    • Murine tissue factor gene expression in vivo. Tissue and cell specificity and regulation by lipopolysaccharide
    • Mackman N, Sawdey MS, Keeton MR, Loskutoff DJ: Murine tissue factor gene expression in vivo. Tissue and cell specificity and regulation by lipopolysaccharide. Am J Pathol 1993;14 3 : 76- 8 4.
    • (1993) Am J Pathol , vol.14 , Issue.3
    • Mackman, N.1    Sawdey, M.S.2    Keeton, M.R.3    Loskutoff, D.J.4
  • 30
    • 27644540541 scopus 로고    scopus 로고
    • Tissue-specific hemostasis in mice
    • Mackman N: Tissue-specific hemostasis in mice. Arterioscler Thromb Vasc Biol 2005;25:2273-2281.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 2273-2281
    • Mackman, N.1
  • 31
    • 13844319153 scopus 로고    scopus 로고
    • Thrombophilia in cancer
    • Falanga A: Thrombophilia in cancer. Semin Thromb Hemost 2005;31:104-110.
    • (2005) Semin Thromb Hemost , vol.31 , pp. 104-110
    • Falanga, A.1
  • 32
    • 33748454321 scopus 로고    scopus 로고
    • Mechanisms of cancer-induced thrombosis in cancer
    • Rickles FR: Mechanisms of cancer-induced thrombosis in cancer. Pathophysiol Haemost Thromb 2006;35:103-110.
    • (2006) Pathophysiol Haemost Thromb , vol.35 , pp. 103-110
    • Rickles, F.R.1
  • 33
    • 34547630092 scopus 로고    scopus 로고
    • Mackman N, Tilley RE, Key NS: Role of the extrinsic pathway of blood coagulation in hemostasis and thrombosis. Arterioscler Thromb Vasc Biol 2007;27: 16 8 7-16 9 3 .
    • Mackman N, Tilley RE, Key NS: Role of the extrinsic pathway of blood coagulation in hemostasis and thrombosis. Arterioscler Thromb Vasc Biol 2007;27: 16 8 7-16 9 3 .
  • 34
    • 34250158455 scopus 로고    scopus 로고
    • The tissue factor-factor VIIa complex: Procoagulant activity, regulation, and multitasking
    • Monroe DM, Key NS: The tissue factor-factor VIIa complex: procoagulant activity, regulation, and multitasking. J Thromb Haemost 2007;5: 1097-1105.
    • (2007) J Thromb Haemost , vol.5 , pp. 1097-1105
    • Monroe, D.M.1    Key, N.S.2
  • 35
    • 52049119056 scopus 로고    scopus 로고
    • Regulation of tissue factor procoagulant activity by post-translational modifications
    • Egorina EM, Sovershaev MA, Osterud B: Regulation of tissue factor procoagulant activity by post-translational modifications. Thromb Res 2008;122:831-837.
    • (2008) Thromb Res , vol.122 , pp. 831-837
    • Egorina, E.M.1    Sovershaev, M.A.2    Osterud, B.3
  • 36
    • 0030857071 scopus 로고    scopus 로고
    • Mackman N: Regulation of the tissue factor gene. Thromb Haemost 1997;78: 74 7-7 5 4 .
    • Mackman N: Regulation of the tissue factor gene. Thromb Haemost 1997;78: 74 7-7 5 4 .
  • 37
    • 5444269969 scopus 로고    scopus 로고
    • Emerging roles of tissue factor in viral hemorrhagic fever
    • Ruf W: Emerging roles of tissue factor in viral hemorrhagic fever. Trends Immunol 2004;25:461-464.
    • (2004) Trends Immunol , vol.25 , pp. 461-464
    • Ruf, W.1
  • 38
    • 0033790217 scopus 로고    scopus 로고
    • Tissue factor encryption/de-encryption is not altered in the absence of the cytoplasmic domain
    • Carson SD, Bromberg ME: Tissue factor encryption/de-encryption is not altered in the absence of the cytoplasmic domain. Thromb Haemost 2000;84: 657- 6 63.
    • (2000) Thromb Haemost , vol.84
    • Carson, S.D.1    Bromberg, M.E.2
  • 40
    • 0037391809 scopus 로고    scopus 로고
    • A lternatively spliced human tissue factor: A circulating, soluble, thrombogenic protein
    • Bogdanov VY, Balasubramanian V, Hathcock J, Vele O, Lieb M, Nemerson Y: A lternatively spliced human tissue factor: a circulating, soluble, thrombogenic protein. Nat Med 2003;9:458-462.
    • (2003) Nat Med , vol.9 , pp. 458-462
    • Bogdanov, V.Y.1    Balasubramanian, V.2    Hathcock, J.3    Vele, O.4    Lieb, M.5    Nemerson, Y.6
  • 41
    • 33644856657 scopus 로고    scopus 로고
    • Identification of a novel human tissue factor splice variant that is upregulated in tumor cells
    • Chand HS, Ness SA, Kisiel W: Identification of a novel human tissue factor splice variant that is upregulated in tumor cells. Int J Cancer 2006;118: 1713-1720.
    • (2006) Int J Cancer , vol.118 , pp. 1713-1720
    • Chand, H.S.1    Ness, S.A.2    Kisiel, W.3
  • 44
    • 9144262380 scopus 로고    scopus 로고
    • Active tissue factor in blood?
    • Butenas S, Mann KG: Active tissue factor in blood? Nat Med 2004;10:1155-1156.
    • (2004) Nat Med , vol.10 , pp. 1155-1156
    • Butenas, S.1    Mann, K.G.2
  • 46
    • 13244271290 scopus 로고    scopus 로고
    • Shedding of tissue factor (TF)-containing microparticles rather than alternatively spliced TF is the main source of TF activity released from human cancer cells
    • Yu JL, Rak JW: Shedding of tissue factor (TF)-containing microparticles rather than alternatively spliced TF is the main source of TF activity released from human cancer cells. J Thromb Haemost 2004;2: 2065-2067.
    • (2004) J Thromb Haemost , vol.2 , pp. 2065-2067
    • Yu, J.L.1    Rak, J.W.2
  • 47
    • 23944509766 scopus 로고    scopus 로고
    • Tissue-factor-bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation
    • Del Conde I, Shrimpton CN, Thiagarajan P, Lopez JA: Tissue-factor-bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation. Blood 2005;106:1604-1611.
    • (2005) Blood , vol.106 , pp. 1604-1611
    • Del Conde, I.1    Shrimpton, C.N.2    Thiagarajan, P.3    Lopez, J.A.4
  • 49
    • 33947308915 scopus 로고    scopus 로고
    • Plasma tissue factor antigen in localized prostate cancer: Distribution, clinical significance and correlation with haemostatic activation markers
    • Langer F, Chun FK, Amirkhosravi A, Friedrich M, Leuenroth S, Eifrig B, Bokemeyer C, Francis JL: Plasma tissue factor antigen in localized prostate cancer: distribution, clinical significance and correlation with haemostatic activation markers. Thromb Haemost 2007;97:464-470.
    • (2007) Thromb Haemost , vol.97 , pp. 464-470
    • Langer, F.1    Chun, F.K.2    Amirkhosravi, A.3    Friedrich, M.4    Leuenroth, S.5    Eifrig, B.6    Bokemeyer, C.7    Francis, J.L.8
  • 51
    • 33846941576 scopus 로고    scopus 로고
    • Tissue factor-positive microparticles: Cellular origin and association with coagulation activation in patients with colorectal cancer
    • Hron G, Kollars M, Weber H, Sagaster V, Quehenberger P, Eichinger S, Kyrle PA, Weltermann A: Tissue factor-positive microparticles: cellular origin and association with coagulation activation in patients with colorectal cancer. Thromb Haemost 2007;97: 119-123.
    • (2007) Thromb Haemost , vol.97 , pp. 119-123
    • Hron, G.1    Kollars, M.2    Weber, H.3    Sagaster, V.4    Quehenberger, P.5    Eichinger, S.6    Kyrle, P.A.7    Weltermann, A.8
  • 54
    • 43749093560 scopus 로고    scopus 로고
    • Tissue factor activity is increased in a combined platelet and microparticle sample from cancer patients
    • Tilley RE, Holscher T, Belani R, Nieva J, Mackman N: Tissue factor activity is increased in a combined platelet and microparticle sample from cancer patients. Thromb Res 2008.
    • (2008) Thromb Res
    • Tilley, R.E.1    Holscher, T.2    Belani, R.3    Nieva, J.4    Mackman, N.5
  • 56
    • 0037077720 scopus 로고    scopus 로고
    • Biochemical properties of platelet microparticle membranes formed during exocytosis resemble organelles more than plasma membrane
    • Olas B, Lundell K, Holmsen H, Fukami MH: Biochemical properties of platelet microparticle membranes formed during exocytosis resemble organelles more than plasma membrane. FEBS Lett 2002;525 : 29-32 .
    • (2002) FEBS Lett , vol.525 , pp. 29-32
    • Olas, B.1    Lundell, K.2    Holmsen, H.3    Fukami, M.H.4
  • 57
    • 13544256266 scopus 로고    scopus 로고
    • Oncogenic events regulate tissue factor expression in colorectal cancer cells: Implications for tumor progression and an-giogenesis
    • Yu JL, May L, Lhotak V, Shahrzad S, Shirasawa S, Weitz JI, Coomber BL, Mackman N, Rak JW: Oncogenic events regulate tissue factor expression in colorectal cancer cells: implications for tumor progression and an-giogenesis. Blood 2005;105:1734-1741.
    • (2005) Blood , vol.105 , pp. 1734-1741
    • Yu, J.L.1    May, L.2    Lhotak, V.3    Shahrzad, S.4    Shirasawa, S.5    Weitz, J.I.6    Coomber, B.L.7    Mackman, N.8    Rak, J.W.9
  • 58
    • 0032725206 scopus 로고    scopus 로고
    • Mechanisms of cellular activation by platelet microparticles
    • Barry OP, FitzGerald GA: Mechanisms of cellular activation by platelet microparticles. Thromb Haemost 1999;82: 794-80 0.
    • (1999) Thromb Haemost , vol.82 , Issue.794 -80 , pp. 0
    • Barry, O.P.1    FitzGerald, G.A.2
  • 59
    • 0033999142 scopus 로고    scopus 로고
    • Elevated levels of shed membrane microparticles with procoagulant potential in the peripheral circulating blood of patients with acute coronary syndromes
    • Mallat Z, Benamer H, Hugel B, Benessiano J, Steg PG, Freyssinet JM, Tedgui A: Elevated levels of shed membrane microparticles with procoagulant potential in the peripheral circulating blood of patients with acute coronary syndromes. Circulation 2000;101: 841-843.
    • (2000) Circulation , vol.101 , pp. 841-843
    • Mallat, Z.1    Benamer, H.2    Hugel, B.3    Benessiano, J.4    Steg, P.G.5    Freyssinet, J.M.6    Tedgui, A.7
  • 60
    • 3042716498 scopus 로고    scopus 로고
    • Cellular microparticles: New players in the field of vascular disease?
    • Diamant M, Tushuizen ME, Sturk A, Nieuw-land R: Cellular microparticles: new players in the field of vascular disease? Eur J Clin Invest 2004;34:392-401.
    • (2004) Eur J Clin Invest , vol.34 , pp. 392-401
    • Diamant, M.1    Tushuizen, M.E.2    Sturk, A.3    Nieuw-land, R.4
  • 61
    • 0032891440 scopus 로고    scopus 로고
    • Shed membrane microparticles with procoagulant potential in human atherosclerotic plaques: A role for apoptosis in plaque thrombogenicity
    • Ma llat Z , Hugel B, Oha n J, Lesèche G, Freyssinet JM, Tedgui A: Shed membrane microparticles with procoagulant potential in human atherosclerotic plaques: a role for apoptosis in plaque thrombogenicity. Circulation 1999;99:348-353.
    • (1999) Circulation , vol.99 , pp. 348-353
    • Ma llat, Z.1    Hugel, B.2    Oha n, J.3    Lesèche, G.4    Freyssinet, J.M.5    Tedgui, A.6
  • 63
    • 0034141849 scopus 로고    scopus 로고
    • Nieuwland R, Berckmans RJ, McGregor S, Boing AN, Romijn FP, Westendor p RG, Hack CE, Sturk A: Cellular origin and procoagulant properties of microparticles in meningococca l sepsis. Blood 20 00;95: 930-935.
    • Nieuwland R, Berckmans RJ, McGregor S, Boing AN, Romijn FP, Westendor p RG, Hack CE, Sturk A: Cellular origin and procoagulant properties of microparticles in meningococca l sepsis. Blood 20 00;95: 930-935.
  • 64
    • 0035002186 scopus 로고    scopus 로고
    • Microparticles from patients with multiple organ dysfunction syndrome and sepsis support coagulation through multiple mechanisms
    • Joop K, Berckmans RJ, Nieuwland R, Berkhout J, Romijn FP, Hack CE, Sturk A: Microparticles from patients with multiple organ dysfunction syndrome and sepsis support coagulation through multiple mechanisms. Thromb Haemost 2001;85:810-820 .
    • (2001) Thromb Haemost , vol.85 , pp. 810-820
    • Joop, K.1    Berckmans, R.J.2    Nieuwland, R.3    Berkhout, J.4    Romijn, F.P.5    Hack, C.E.6    Sturk, A.7
  • 66
    • 0031886679 scopus 로고    scopus 로고
    • The role of the tissue factor pathway in the hypercoagulable state in patients with the antiphospholipid syndrome
    • Amengual O, Atsumi T, Khamashta MA, Hughes GR: The role of the tissue factor pathway in the hypercoagulable state in patients with the antiphospholipid syndrome. Thromb Haemost 1998;79:276-281.
    • (1998) Thromb Haemost , vol.79 , pp. 276-281
    • Amengual, O.1    Atsumi, T.2    Khamashta, M.A.3    Hughes, G.R.4
  • 67
    • 33645551730 scopus 로고    scopus 로고
    • Pereira J, Alfaro G, Goycoolea M, Quiroga T, Ocqueteau M, Massardo L, Perez C, Saez C, Panes O, Matus V, Mezzano D: Circulating platelet-derived microparticles in systemic lupus erythematosus. Association with increased thrombin generation and procoagu-lant state. Thromb Haemost 20 06;95:94-99.
    • Pereira J, Alfaro G, Goycoolea M, Quiroga T, Ocqueteau M, Massardo L, Perez C, Saez C, Panes O, Matus V, Mezzano D: Circulating platelet-derived microparticles in systemic lupus erythematosus. Association with increased thrombin generation and procoagu-lant state. Thromb Haemost 20 06;95:94-99.
  • 70
    • 0037027467 scopus 로고    scopus 로고
    • Elevated numbers of tissue-factor exposing microparticles correlate with components of the metabolic syndrome in uncomplicated type 2 diabetes mellitus
    • Diamant M, Nieuwland R, Pablo RF, Sturk A, Smit JW, Radder JK: Elevated numbers of tissue-factor exposing microparticles correlate with components of the metabolic syndrome in uncomplicated type 2 diabetes mellitus. Circulation 2002;106:2442-2447.
    • (2002) Circulation , vol.106 , pp. 2442-2447
    • Diamant, M.1    Nieuwland, R.2    Pablo, R.F.3    Sturk, A.4    Smit, J.W.5    Radder, J.K.6
  • 72
    • 41549125361 scopus 로고    scopus 로고
    • D'Addario G, Rauch D, Stupp R, Pless M, Stahel R, Mach N, Jost L, Widmer L, Tapia C, BihlM, Mayer M, Ribi K, L erch S , Bubendor f L, Betticher DC: Multicenter phase II trial of gefitinib first-line therapy followed by chemotherapy in advanced non-small-cell lung cancer (NSCLC): SAKK Protocol 19/03. Ann Oncol 2008;19:739-745.
    • D'Addario G, Rauch D, Stupp R, Pless M, Stahel R, Mach N, Jost L, Widmer L, Tapia C, BihlM, Mayer M, Ribi K, L erch S , Bubendor f L, Betticher DC: Multicenter phase II trial of gefitinib first-line therapy followed by chemotherapy in advanced non-small-cell lung cancer (NSCLC): SAKK Protocol 19/03. Ann Oncol 2008;19:739-745.
  • 73
    • 68249134260 scopus 로고    scopus 로고
    • Trousseau A: Phlegmasia alba dolens;in Trousseau A (ed): Clinique médicinale de l'Hôtel-Dieu de Paris. Paris, J.-B. Baillière &Fils, 1865, pp 645-712.
    • Trousseau A: Phlegmasia alba dolens;in Trousseau A (ed): Clinique médicinale de l'Hôtel-Dieu de Paris. Paris, J.-B. Baillière &Fils, 1865, pp 645-712.
  • 74
    • 0141498201 scopus 로고    scopus 로고
    • From Trousseau to targeted therapy: New insights and innovations in thrombosis and cancer
    • Levine MN, Lee AY, Kakkar AK: From Trousseau to targeted therapy: new insights and innovations in thrombosis and cancer. J Thromb Haemost 2003;1:1456-1463.
    • (2003) J Thromb Haemost , vol.1 , pp. 1456-1463
    • Levine, M.N.1    Lee, A.Y.2    Kakkar, A.K.3
  • 75
    • 34250706406 scopus 로고    scopus 로고
    • Cancer and thrombosis: From molecular mechanisms to clinical presentations
    • Buller HR, van Doormaal FF, van Sluis GL, Kamphuisen PW: Cancer and thrombosis: from molecular mechanisms to clinical presentations. J Thromb Haemost 2007;5(suppl 1):246-254.
    • (2007) J Thromb Haemost , vol.5 , Issue.SUPPL. 1 , pp. 246-254
    • Buller, H.R.1    van Doormaal, F.F.2    van Sluis, G.L.3    Kamphuisen, P.W.4
  • 77
  • 78
    • 23844481864 scopus 로고    scopus 로고
    • Mechanisms of disease: The impact of antithrombotic therapy in cancer patients
    • Petralia GA, Lemoine NR, Kakkar AK: Mechanisms of disease: the impact of antithrombotic therapy in cancer patients. Nat Clin Pract Oncol 2005;2:356-363.
    • (2005) Nat Clin Pract Oncol , vol.2 , pp. 356-363
    • Petralia, G.A.1    Lemoine, N.R.2    Kakkar, A.K.3
  • 79
    • 0030964305 scopus 로고    scopus 로고
    • Cancer procoagu-lant: A factor X activator, tumor marker and growth factor from malignant tissue
    • Gordon SG, Mielicki WP: Cancer procoagu-lant: a factor X activator, tumor marker and growth factor from malignant tissue. Blood Coagul Fibrinolysis 1997;8:73-86.
    • (1997) Blood Coagul Fibrinolysis , vol.8 , pp. 73-86
    • Gordon, S.G.1    Mielicki, W.P.2
  • 80
    • 9444255255 scopus 로고    scopus 로고
    • Tamoxi-fen-induced tissue factor pathway inhibitor reduction: A clue for an acquired thrombo-philic state?
    • Erman M, Abali H, Oran B, Haznedaroglu IC, Canpinar H, Kirazli S, Celik I: Tamoxi-fen-induced tissue factor pathway inhibitor reduction: a clue for an acquired thrombo-philic state? Ann Oncol 2004;15:1622-1626.
    • (2004) Ann Oncol , vol.15 , pp. 1622-1626
    • Erman, M.1    Abali, H.2    Oran, B.3    Haznedaroglu, I.C.4    Canpinar, H.5    Kirazli, S.6    Celik, I.7
  • 81
    • 13444291198 scopus 로고    scopus 로고
    • Epigenetic inactivation of TFPI-2 as a common mechanism associated with growth and invasion of pancreatic ductalad-enocarcinoma
    • Sato N, Parker AR, Fukushima N, Miyagi Y, Iacobuzio-Donahue CA, Eshleman JR, Goggins M: Epigenetic inactivation of TFPI-2 as a common mechanism associated with growth and invasion of pancreatic ductalad-enocarcinoma. Oncogene 2005;24:850-858.
    • (2005) Oncogene , vol.24 , pp. 850-858
    • Sato, N.1    Parker, A.R.2    Fukushima, N.3    Miyagi, Y.4    Iacobuzio-Donahue, C.A.5    Eshleman, J.R.6    Goggins, M.7
  • 83
    • 20444433198 scopus 로고    scopus 로고
    • In vitro procoagulant activity induced in endothelial cells by chemotherapy and antiangiogenic drug combinations: Modulation by lower-dose chemotherapy
    • Ma L, Francia G, Viloria-Petit A, Hicklin DJ, du MJ, Rak J, Kerbel RS: In vitro procoagulant activity induced in endothelial cells by chemotherapy and antiangiogenic drug combinations: modulation by lower-dose chemotherapy. Cancer Res 2005;65:5365-5373.
    • (2005) Cancer Res , vol.65 , pp. 5365-5373
    • Ma, L.1    Francia, G.2    Viloria-Petit, A.3    Hicklin4    DJ, D.M.5    Rak, J.6    Kerbel, R.S.7
  • 85
  • 86
    • 33845288991 scopus 로고    scopus 로고
    • Oncogenes, Trousseau syndrome, and cancer-related changes in the coagulome of mice and humans
    • Rak J, Yu JL, Luyendyk J, Mackman N: Oncogenes, Trousseau syndrome, and cancer-related changes in the coagulome of mice and humans. Cancer Res 2006;66:10643-10646.
    • (2006) Cancer Res , vol.66 , pp. 10643-10646
    • Rak, J.1    Yu, J.L.2    Luyendyk, J.3    Mackman, N.4
  • 88
    • 1842607586 scopus 로고    scopus 로고
    • On-cogenes as regulators of tissue factor expression in cancer: Implications for tumor angiogenesis and anti-cancer therapy
    • Yu JL, May L, Klement P, Weitz JI, Rak J: On-cogenes as regulators of tissue factor expression in cancer: implications for tumor angiogenesis and anti-cancer therapy. Semin Thromb Hemost 2004;30:21-30.
    • (2004) Semin Thromb Hemost , vol.30 , pp. 21-30
    • Yu, J.L.1    May, L.2    Klement, P.3    Weitz, J.I.4    Rak, J.5
  • 89
    • 13244277933 scopus 로고    scopus 로고
    • Effects of all-trans-retinoic acid or chemotherapy on the molecular regulation of systemic blood coagulation and fibri-nolysis in patients with acute promyelocytic leukemia
    • Tallman MS, Lefebvre P, Baine RM, Shoji M, Cohen I, Green D, Kwaan HC, Paietta E, Rickles FR: Effects of all-trans-retinoic acid or chemotherapy on the molecular regulation of systemic blood coagulation and fibri-nolysis in patients with acute promyelocytic leukemia. J Thromb Haemost 2004;2:1341-1350.
    • (2004) J Thromb Haemost , vol.2 , pp. 1341-1350
    • Tallman, M.S.1    Lefebvre, P.2    Baine, R.M.3    Shoji, M.4    Cohen, I.5    Green, D.6    Kwaan, H.C.7    Paietta, E.8    Rickles, F.R.9
  • 90
    • 13944256192 scopus 로고    scopus 로고
    • PTEN and hypoxia regulate tissue factor expression and plasma coagulation by glioblastoma
    • Rong Y, Post DE, Pieper RO, Durden DL, Van Meir EG, Brat DJ: PTEN and hypoxia regulate tissue factor expression and plasma coagulation by glioblastoma. Cancer Res 2005;65:1406-1413.
    • (2005) Cancer Res , vol.65 , pp. 1406-1413
    • Rong, Y.1    Post, D.E.2    Pieper, R.O.3    Durden, D.L.4    Van Meir, E.G.5    Brat, D.J.6
  • 91
    • 33751253447 scopus 로고    scopus 로고
    • Trousseau's syndrome associated with tissue factor produced by pulmonary adenocarcinoma
    • Sato T, Tsujino I, Ikeda D, Ieko M, Nishimura M: Trousseau's syndrome associated with tissue factor produced by pulmonary adenocarcinoma. Thorax 2006;61:1009-1010.
    • (2006) Thorax , vol.61 , pp. 1009-1010
    • Sato, T.1    Tsujino, I.2    Ikeda, D.3    Ieko, M.4    Nishimura, M.5
  • 92
    • 0029097464 scopus 로고    scopus 로고
    • Kakkar AK, Lemoine NR, Scully MF, Tebbutt S, Williamson RC: Tissue factor expression correlates with histological grade in human pancreatic cancer. Br J Surg 1995;82: 1101-110 4.
    • Kakkar AK, Lemoine NR, Scully MF, Tebbutt S, Williamson RC: Tissue factor expression correlates with histological grade in human pancreatic cancer. Br J Surg 1995;82: 1101-110 4.
  • 93
    • 0034086722 scopus 로고    scopus 로고
    • Tissue factor expression in breast cancer tissues: Its correlation with prognosis and plasma concentration
    • Ueno T, Toi M, Koike M, Nakamura S, Tominaga T: Tissue factor expression in breast cancer tissues: its correlation with prognosis and plasma concentration. Br J Cancer 2000;83:164-170.
    • (2000) Br J Cancer , vol.83 , pp. 164-170
    • Ueno, T.1    Toi, M.2    Koike, M.3    Nakamura, S.4    Tominaga, T.5
  • 95
    • 0034770081 scopus 로고    scopus 로고
    • The hemostatic system and angiogenesis in malignancy
    • Wojtukiewicz MZ, Sierko E, Klement P, Rak J: The hemostatic system and angiogenesis in malignancy. Neoplasia 2001;3: 371-384.
    • (2001) Neoplasia , vol.3 , pp. 371-384
    • Wojtukiewicz, M.Z.1    Sierko, E.2    Klement, P.3    Rak, J.4
  • 96
    • 0027071674 scopus 로고
    • Expression of tissue factor by melanoma cells promotes efficient hematogenous metastasis
    • Mueller BM, Reisfeld RA, Edgington TS, Ruf W: Expression of tissue factor by melanoma cells promotes efficient hematogenous metastasis. Proc Natl Acad Sci USA 1992;89:11832-11836.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 11832-11836
    • Mueller, B.M.1    Reisfeld, R.A.2    Edgington, T.S.3    Ruf, W.4
  • 97
    • 0034650704 scopus 로고    scopus 로고
    • Tissue factor expression in human colorectal carcinoma: Correlation with hepatic metastasis and impact on prognosis
    • Seto S, Onodera H, Kaido T, Yoshikawa A, Ishigami S, Arii S, Imamura M: Tissue factor expression in human colorectal carcinoma: correlation with hepatic metastasis and impact on prognosis. Cancer 2000;88: 295-301.
    • (2000) Cancer , vol.88 , pp. 295-301
    • Seto, S.1    Onodera, H.2    Kaido, T.3    Yoshikawa, A.4    Ishigami, S.5    Arii, S.6    Imamura, M.7
  • 99
    • 0036202118 scopus 로고    scopus 로고
    • Expression of tissue factor and vascular endothelial growth factor is associated with angiogenesis in colorectal cancer
    • Nakasaki T, Wada H, Shigemori C, Miki C, Gabazza EC, Nobori T, Nakamura S, Shiku H: Expression of tissue factor and vascular endothelial growth factor is associated with angiogenesis in colorectal cancer. Am J Hematol 2002;69:247-254.
    • (2002) Am J Hematol , vol.69 , pp. 247-254
    • Nakasaki, T.1    Wada, H.2    Shigemori, C.3    Miki, C.4    Gabazza, E.C.5    Nobori, T.6    Nakamura, S.7    Shiku, H.8
  • 100
    • 25144521282 scopus 로고    scopus 로고
    • Regulation of vascular endothelial growth factor production and angiogenesis by tissue factor in SGC-7901 gastric cancer cells
    • Zhang J, Ding J, Zhang X, Shao X, Hao Z: Regulation of vascular endothelial growth factor production and angiogenesis by tissue factor in SGC-7901 gastric cancer cells. Cancer Biol Ther 2005;4:769-772.
    • (2005) Cancer Biol Ther , vol.4 , pp. 769-772
    • Zhang, J.1    Ding, J.2    Zhang, X.3    Shao, X.4    Hao, Z.5
  • 101
    • 0037189580 scopus 로고    scopus 로고
    • Factor VIIa induces tissue factor-dependent up-regula-tion of interleukin-8 in a human keratinocyte line
    • Wang X, Gjernes E, Prydz H: Factor VIIa induces tissue factor-dependent up-regula-tion of interleukin-8 in a human keratinocyte line. J Biol Chem 2002;277:23620-23626.
    • (2002) J Biol Chem , vol.277 , pp. 23620-23626
    • Wang, X.1    Gjernes, E.2    Prydz, H.3
  • 102
    • 0037443535 scopus 로고    scopus 로고
    • A chemically defined culture of VEGFR2+ cells derived from embryonic stem cells reveals the role of VEGFR1 in tuning the threshold for VEGF in developing endothelial cel ls
    • Hirashima M, Ogawa M, Nishikawa S, Matsumura K, Kawasaki K, Shibuya M, Nishikawa S: A chemically defined culture of VEGFR2+ cells derived from embryonic stem cells reveals the role of VEGFR1 in tuning the threshold for VEGF in developing endothelial cel ls. Blood 2003;101:2261-2267.
    • (2003) Blood , vol.101 , pp. 2261-2267
    • Hirashima, M.1    Ogawa, M.2    Nishikawa, S.3    Matsumura, K.4    Kawasaki, K.5    Shibuya, M.6    Nishikawa, S.7
  • 105
    • 33846950031 scopus 로고    scopus 로고
    • CNTO 859, a humanized anti-tissue factor monoclonal antibody, is a potent inhibitor of breast cancer metastasis and tumor growth in xenograft models
    • Ngo CV, Picha K, McCabe F, Millar H, Tawadros R, Tam SH, Nakada MT, Anderson GM: CNTO 859, a humanized anti-tissue factor monoclonal antibody, is a potent inhibitor of breast cancer metastasis and tumor growth in xenograft models. Int J Cancer 2007;120:1261-1267.
    • (2007) Int J Cancer , vol.120 , pp. 1261-1267
    • Ngo, C.V.1    Picha, K.2    McCabe, F.3    Millar, H.4    Tawadros, R.5    Tam, S.H.6    Nakada, M.T.7    Anderson, G.M.8
  • 106
    • 36349006372 scopus 로고    scopus 로고
    • Elevated tissue factor procoagulant activity in CD133-positive cancer cells
    • Milsom C, Anderson GM, Weitz JI, Rak J: Elevated tissue factor procoagulant activity in CD133-positive cancer cells. J Thromb Haemost 2007;5:2550-2552.
    • (2007) J Thromb Haemost , vol.5 , pp. 2550-2552
    • Milsom, C.1    Anderson, G.M.2    Weitz, J.I.3    Rak, J.4
  • 109
    • 0035174972 scopus 로고    scopus 로고
    • Specificity, diversity, and convergence in VEGF and TNF-αsignaling events leading to tissue factor up-regulation via EGR-1 in endothelial cells
    • Mechtcheriakova D, Schabbauer G, Lucer-na M, Clauss M, de Martin R, Binder BR Hofer E: Specificity, diversity, and convergence in VEGF and TNF-αsignaling events leading to tissue factor up-regulation via EGR-1 in endothelial cells. FASEB J 2001;15:230-242.
    • (2001) FASEB J , vol.15 , pp. 230-242
    • Mechtcheriakova, D.1    Schabbauer, G.2    Lucer-na, M.3    Clauss, M.4    de Martin, R.5    Binder, B.R.6    Hofer, E.7
  • 110
    • 0032523148 scopus 로고    scopus 로고
    • Tissue factor-dependent vascular endothelial growth factor production by human fibroblasts in response to activated factor VII
    • Ollivier V, Bentolila S, Chabbat J, Hakim J, de Prost D: Tissue factor-dependent vascular endothelial growth factor production by human fibroblasts in response to activated factor VII. Blood 1998;91:2698-2703.
    • (1998) Blood , vol.91 , pp. 2698-2703
    • Ollivier, V.1    Bentolila, S.2    Chabbat, J.3    Hakim, J.4    de Prost, D.5
  • 111
    • 0030956584 scopus 로고    scopus 로고
    • Apoptotic vascular endothelial cells become procoagulant
    • Bombeli T, Karsan A, Tait JF, Harlan JM: Apoptotic vascular endothelial cells become procoagulant. Blood 1997;89:2429-2442.
    • (1997) Blood , vol.89 , pp. 2429-2442
    • Bombeli, T.1    Karsan, A.2    Tait, J.F.3    Harlan, J.M.4
  • 112
    • 0034252924 scopus 로고    scopus 로고
    • Monocyte tissue factor levels in cancer patients
    • Lwaleed BA, Francis JL, Chisholm M: Monocyte tissue factor levels in cancer patients. Saudi Med J 2000;21:722-729.
    • (2000) Saudi Med J , vol.21 , pp. 722-729
    • Lwaleed, B.A.1    Francis, J.L.2    Chisholm, M.3
  • 113
    • 0034672373 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-stimulated endothelial cells promote adhesion and activation of platelets
    • Verheul HM, Jorna AS, Hoekman K, Broxterman HJ, Gebbink MF, Pinedo HM: Vascular endothelial growth factor-stimulated endothelial cells promote adhesion and activation of platelets. Blood 2000;96:4216-4221.
    • (2000) Blood , vol.96 , pp. 4216-4221
    • Verheul, H.M.1    Jorna, A.S.2    Hoekman, K.3    Broxterman, H.J.4    Gebbink, M.F.5    Pinedo, H.M.6
  • 114
    • 33746925159 scopus 로고    scopus 로고
    • Early growth response gene-1 regulates hypoxia-induced expression of tissue factor in glioblastoma multiforme through hypoxia-inducible factor-1-independent mechanisms
    • Rong Y, Hu F, Huang R Mackman N, Horowitz JM, Jensen RL, Durden DL, Van Meir EG, Brat DJ: Early growth response gene-1 regulates hypoxia-induced expression of tissue factor in glioblastoma multiforme through hypoxia-inducible factor-1-independent mechanisms. Cancer Res 2006;66:7067-7074.
    • (2006) Cancer Res , vol.66 , pp. 7067-7074
    • Rong, Y.1    Hu, F.2    Huang, R.3    Mackman, N.4    Horowitz, J.M.5    Jensen, R.L.6    Durden, D.L.7    Van Meir, E.G.8    Brat, D.J.9
  • 115
    • 27144506023 scopus 로고    scopus 로고
    • Regulation of tissue factor and angiogenesis-related genes by changes in cell shape
    • Milsom C, Rak J: Regulation of tissue factor and angiogenesis-related genes by changes in cell shape. Biochem Biophys Res Com-mun 2005;337:1267-1275.
    • (2005) Biochem Biophys Res Com-mun , vol.337 , pp. 1267-1275
    • Milsom, C.1    Rak, J.2
  • 116
    • 23744475201 scopus 로고    scopus 로고
    • Kato S, Pinto M, Carvajal A, Espinoza N, Monso C, Bravo L, Villalon M, Cuello M, Quest AF, Suenaga A, Brosens JJ, Owen GI: Tissue factor is regulated by epidermal growth factor in normal and malignant human endometrial epithelial cells. Thromb Haemost 2005;94:444-453.
    • Kato S, Pinto M, Carvajal A, Espinoza N, Monso C, Bravo L, Villalon M, Cuello M, Quest AF, Suenaga A, Brosens JJ, Owen GI: Tissue factor is regulated by epidermal growth factor in normal and malignant human endometrial epithelial cells. Thromb Haemost 2005;94:444-453.
  • 118
    • 33746696738 scopus 로고    scopus 로고
    • Pseudopalisading' necrosis in glioblastoma: A familiar morphologic feature that links vascular pathology, hypoxia, and angiogenesis
    • Rong Y, Durden DL, Van Meir EG, Brat DJ: 'Pseudopalisading' necrosis in glioblastoma: a familiar morphologic feature that links vascular pathology, hypoxia, and angiogenesis. J Neuropathol Exp Neurol 2006;65:529-539.
    • (2006) J Neuropathol Exp Neurol , vol.65 , pp. 529-539
    • Rong, Y.1    Durden, D.L.2    Van Meir, E.G.3    Brat, D.J.4
  • 119
    • 33748799706 scopus 로고    scopus 로고
    • Evolution of oxygen and glucose concentration profiles in a tissue-mimetic culture system of embryonic stem cells
    • Cochran DM, Fukumura D, Ancukiewicz M, Carmeliet P, Jain RK: Evolution of oxygen and glucose concentration profiles in a tissue-mimetic culture system of embryonic stem cells. Ann Biomed Eng 2006;34: 1247-1258.
    • (2006) Ann Biomed Eng , vol.34 , pp. 1247-1258
    • Cochran, D.M.1    Fukumura, D.2    Ancukiewicz, M.3    Carmeliet, P.4    Jain, R.K.5
  • 120
    • 0034534825 scopus 로고    scopus 로고
    • Impact of oncogenes and tumor suppressor genes on deregulation of hemostasis and angiogenesis in cancer
    • Rak J, Klement G: Impact of oncogenes and tumor suppressor genes on deregulation of hemostasis and angiogenesis in cancer. Cancer Metastasis Rev 2000;19:93-96.
    • (2000) Cancer Metastasis Rev , vol.19 , pp. 93-96
    • Rak, J.1    Klement, G.2
  • 121
    • 1842607586 scopus 로고    scopus 로고
    • Oncogenes as regulators of tissue factor expression in cancer: Implications for tumor angiogenesis and anti-cancer therapy
    • Yu JL, May L, Klement P, Weitz JI, Rak J: Oncogenes as regulators of tissue factor expression in cancer: implications for tumor angiogenesis and anti-cancer therapy. Semin Thromb Hemost 2004;30:21-30.
    • (2004) Semin Thromb Hemost , vol.30 , pp. 21-30
    • Yu, J.L.1    May, L.2    Klement, P.3    Weitz, J.I.4    Rak, J.5
  • 122
    • 33644543744 scopus 로고    scopus 로고
    • Tissue factor in cancer and angiogenesis: The molecular link between genetic tumor progression, tumor neovascularization, and cancer coagulopathy
    • Rak J, Milsom C, May L, Klement P, Yu J: Tissue factor in cancer and angiogenesis: the molecular link between genetic tumor progression, tumor neovascularization, and cancer coagulopathy. Semin Thromb Hemost 2006;32:54-70.
    • (2006) Semin Thromb Hemost , vol.32 , pp. 54-70
    • Rak, J.1    Milsom, C.2    May, L.3    Klement, P.4    Yu, J.5
  • 123
    • 43049139913 scopus 로고    scopus 로고
    • Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells
    • Al-Nedawi K, Meehan B, Micallef J, Lhotak V, May L, Guha A, Rak J: Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells. Nat Cell Biol 2008;10:619-624.
    • (2008) Nat Cell Biol , vol.10 , pp. 619-624
    • Al-Nedawi, K.1    Meehan, B.2    Micallef, J.3    Lhotak, V.4    May, L.5    Guha, A.6    Rak, J.7
  • 124
    • 33645468255 scopus 로고    scopus 로고
    • Klement P, Rak J: Emerging anticoagulants: mechanism of action and future potential. Vnitr Lek 20 06;52(suppl 1):119-122.
    • Klement P, Rak J: Emerging anticoagulants: mechanism of action and future potential. Vnitr Lek 20 06;52(suppl 1):119-122.
  • 125
    • 0034623346 scopus 로고    scopus 로고
    • Tissue factor pathway inhibitor-2 suppresses the production of active matrix metallo-proteinase-2 and is down-regulated in cells harboring activated ras oncogenes
    • Izumi H, Takahashi C, Oh J, Noda M: Tissue factor pathway inhibitor-2 suppresses the production of active matrix metallo-proteinase-2 and is down-regulated in cells harboring activated ras oncogenes. FEBS Lett 2000;481:31-36.
    • (2000) FEBS Lett , vol.481 , pp. 31-36
    • Izumi, H.1    Takahashi, C.2    Oh, J.3    Noda, M.4
  • 127
    • 53949084888 scopus 로고    scopus 로고
    • The thrombin inhibitor Argat-roban reduces breast cancer malignancy and metastasis via osteopontin-dependent and osteopontin-independent mechanisms
    • Schulze EB, Hedley BD, Goodale D, Postenka CO, Al Katib W, Tuck AB, Chambers AF, Allan AL: The thrombin inhibitor Argat-roban reduces breast cancer malignancy and metastasis via osteopontin-dependent and osteopontin-independent mechanisms. Breast Cancer Res Treat 2008;112:243-254.
    • (2008) Breast Cancer Res Treat , vol.112 , pp. 243-254
    • Schulze, E.B.1    Hedley, B.D.2    Goodale, D.3    Postenka, C.O.4    Al Katib, W.5    Tuck, A.B.6    Chambers, A.F.7    Allan, A.L.8
  • 130
    • 0036894405 scopus 로고    scopus 로고
    • Spontaneous hematogenous and lymphatic metastasis, but not primary tumor growth or angiogenesis, is diminished in fibrinogen-deficient mice
    • Palumbo JS, Potter JM, Kaplan LS, Talmage K, Jackson DG, Degen JL: Spontaneous hematogenous and lymphatic metastasis, but not primary tumor growth or angiogenesis, is diminished in fibrinogen-deficient mice. Cancer Res 2002;62:6966-6972.
    • (2002) Cancer Res , vol.62 , pp. 6966-6972
    • Palumbo, J.S.1    Potter, J.M.2    Kaplan, L.S.3    Talmage, K.4    Jackson, D.G.5    Degen, J.L.6
  • 131
    • 0036190121 scopus 로고    scopus 로고
    • Effect of antihemostatic agents on experimental tumor dissemination
    • Francis JL, Amirkhosravi A: Effect of antihemostatic agents on experimental tumor dissemination. Semin Thromb Hemost 2002;28:29-38.
    • (2002) Semin Thromb Hemost , vol.28 , pp. 29-38
    • Francis, J.L.1    Amirkhosravi, A.2
  • 132
    • 0029806633 scopus 로고    scopus 로고
    • Tissue factor in cancer angiogenesis and metastasis
    • Ruf W, Mueller BM: Tissue factor in cancer angiogenesis and metastasis. Curr Opin Hematol 1996;3:379-384.
    • (1996) Curr Opin Hematol , vol.3 , pp. 379-384
    • Ruf, W.1    Mueller, B.M.2
  • 135
    • 34249294557 scopus 로고    scopus 로고
    • Possible molecular mechanisms involved in the toxicity of angiogenesis inhibition
    • Verheul HM, Pinedo HM: Possible molecular mechanisms involved in the toxicity of angiogenesis inhibition. Nat Rev Cancer 2007;7:475-485.
    • (2007) Nat Rev Cancer , vol.7 , pp. 475-485
    • Verheul, H.M.1    Pinedo, H.M.2
  • 137
    • 11144357000 scopus 로고    scopus 로고
    • Identification and characterization of a very low density lipoprotein receptor binding peptide from tissue factor pathway inhibitor that has antitumor and antiangiogenic activity
    • Hembrough TA, Ruiz JF, Swerdlow BM, Swartz GM, Hammers HJ, Zhang L, Plum SM, Williams MS, Strickland DK, Pribluda VS: Identification and characterization of a very low density lipoprotein receptor binding peptide from tissue factor pathway inhibitor that has antitumor and antiangiogenic activity. Blood 2004;103:3374-3380.
    • (2004) Blood , vol.103 , pp. 3374-3380
    • Hembrough, T.A.1    Ruiz, J.F.2    Swerdlow, B.M.3    Swartz, G.M.4    Hammers, H.J.5    Zhang, L.6    Plum, S.M.7    Williams, M.S.8    Strickland, D.K.9    Pribluda, V.S.10
  • 139
    • 8644287603 scopus 로고    scopus 로고
    • Downregulation of tissue factor by RNA interference in human melanoma LOX-L cells reduces pulmonary metastasis in nude mice
    • Wang X, Wang M, Amarzguioui M, Liu F, Fodstad O, Prydz H: Downregulation of tissue factor by RNA interference in human melanoma LOX-L cells reduces pulmonary metastasis in nude mice. Int J Cancer 2004;112:994-1002.
    • (2004) Int J Cancer , vol.112 , pp. 994-1002
    • Wang, X.1    Wang, M.2    Amarzguioui, M.3    Liu, F.4    Fodstad, O.5    Prydz, H.6
  • 140
    • 34347385401 scopus 로고    scopus 로고
    • Tumor cell-associated tissue factor and circulating hemostatic factors cooperate to increase metastatic potential through natural killer cell-dependent and-independent mechanisms
    • Palumbo JS, Talmage KE, Massari JV, La Jeunesse CM, Flick MJ, Kombrinck KW, Hu Z, Barney KA, Degen JL: Tumor cell-associated tissue factor and circulating hemostatic factors cooperate to increase metastatic potential through natural killer cell-dependent and-independent mechanisms. Blood 2007;110:133-141.
    • (2007) Blood , vol.110 , pp. 133-141
    • Palumbo, J.S.1    Talmage, K.E.2    Massari, J.V.3    La Jeunesse, C.M.4    Flick, M.J.5    Kombrinck, K.W.6    Hu, Z.7    Barney, K.A.8    Degen, J.L.9
  • 141
    • 26444520787 scopus 로고    scopus 로고
    • Combination antibody therapy targeting both xenograft-and host-derived tissue factor leads to potent tumor inhibition
    • abstr 548
    • Ngo CV, Manning CA, McCabe F, Millar H, Nakada MT, Anderson GM: Combination antibody therapy targeting both xenograft-and host-derived tissue factor leads to potent tumor inhibition. Proc Am Assoc Cancer Res 2005;46 (abstr 548).
    • (2005) Proc Am Assoc Cancer Res , pp. 46
    • Ngo, C.V.1    Manning, C.A.2    McCabe, F.3    Millar, H.4    Nakada, M.T.5    Anderson, G.M.6
  • 142
    • 0023110174 scopus 로고
    • Clonality of pulmonary metastases from the bladder 6 subline of the B16 melanoma studied by Southern hybridization
    • Talmadge JE, Zbar B: Clonality of pulmonary metastases from the bladder 6 subline of the B16 melanoma studied by Southern hybridization. J Natl Cancer Inst 1987;78: 315-320.
    • (1987) J Natl Cancer Inst , vol.78 , pp. 315-320
    • Talmadge, J.E.1    Zbar, B.2
  • 144
    • 33644543744 scopus 로고    scopus 로고
    • Tissue factor in cancer and angiogenesis: The molecular link between genetic tumor progression, tumor neovascularization, and cancer coagulopathy
    • Rak J, Milsom C, May L, Klement P, Yu J: Tissue factor in cancer and angiogenesis: the molecular link between genetic tumor progression, tumor neovascularization, and cancer coagulopathy. Semin Thromb Hemost 2006;32:54-70.
    • (2006) Semin Thromb Hemost , vol.32 , pp. 54-70
    • Rak, J.1    Milsom, C.2    May, L.3    Klement, P.4    Yu, J.5
  • 145
    • 23944466494 scopus 로고    scopus 로고
    • Hypercoagulability preceding cancer. Does hypercoagulability awaken dormant tumor cells in the host?
    • Nierodzik M, Karpatkin S: Hypercoagulability preceding cancer. Does hypercoagulability awaken dormant tumor cells in the host? J Thromb Haemost 2005;3:577-580.
    • (2005) J Thromb Haemost , vol.3 , pp. 577-580
    • Nierodzik, M.1    Karpatkin, S.2
  • 146
    • 16244364806 scopus 로고    scopus 로고
    • Methylation and inhibition of expression of uPA by the RAS oncogene: Divergence of growth control and invasion in breast cancer cells
    • Pakneshan P, Szyf M, Rabbani SA: Methylation and inhibition of expression of uPA by the RAS oncogene: divergence of growth control and invasion in breast cancer cells. Carcinogenesis 2005;26:557-564.
    • (2005) Carcinogenesis , vol.26 , pp. 557-564
    • Pakneshan, P.1    Szyf, M.2    Rabbani, S.A.3
  • 148
    • 1842471880 scopus 로고    scopus 로고
    • Angiogenesis and proteins of the hemostatic system
    • Folkman J: Angiogenesis and proteins of the hemostatic system. J Thromb Haemost 2003;1:1681-1682.
    • (2003) J Thromb Haemost , vol.1 , pp. 1681-1682
    • Folkman, J.1
  • 149
    • 0034695685 scopus 로고    scopus 로고
    • The hemostatic system as a regulator of angiogenesis
    • Browder T, Folkman J, Pirie-Shepherd S: The hemostatic system as a regulator of angiogenesis. J Biol Chem 2000;275:1521-1524.
    • (2000) J Biol Chem , vol.275 , pp. 1521-1524
    • Browder, T.1    Folkman, J.2    Pirie-Shepherd, S.3
  • 150
    • 0002982369 scopus 로고    scopus 로고
    • Tumor growth: A putative role for platelets?
    • Verheul HM, Pinedo HM: Tumor growth: a putative role for platelets? Oncologist 1998;3:ii.
    • (1998) Oncologist , vol.3 , Issue.II
    • Verheul, H.M.1    Pinedo, H.M.2
  • 151
    • 0030020590 scopus 로고    scopus 로고
    • In situ detection of tissue factor in vascular endothelial cells: Correlation with the malignant phenotype of human breast disease
    • Contrino J, Hair G, Kreutzer DL, Rickles FR: In situ detection of tissue factor in vascular endothelial cells: correlation with the malignant phenotype of human breast disease. Nat Med 1996;2:209-215.
    • (1996) Nat Med , vol.2 , pp. 209-215
    • Contrino, J.1    Hair, G.2    Kreutzer, D.L.3    Rickles, F.R.4
  • 152
    • 34648821254 scopus 로고    scopus 로고
    • Making a tumour's bed: Glioblastoma stem cells and the vascular niche
    • Gilbertson RJ, Rich JN: Making a tumour's bed: glioblastoma stem cells and the vascular niche. Nat Rev Cancer 2007;7:733-736.
    • (2007) Nat Rev Cancer , vol.7 , pp. 733-736
    • Gilbertson, R.J.1    Rich, J.N.2
  • 153
    • 35148888629 scopus 로고    scopus 로고
    • Cancer stem cells in radiation resistance
    • Rich JN: Cancer stem cells in radiation resistance. Cancer Res 2007;67:8980-8984.
    • (2007) Cancer Res , vol.67 , pp. 8980-8984
    • Rich, J.N.1
  • 154
    • 0141988568 scopus 로고    scopus 로고
    • Fundamental concepts of the angiogenic process
    • Folkman J: Fundamental concepts of the angiogenic process. Curr Mol Med 2003;3: 643-651.
    • (2003) Curr Mol Med , vol.3 , pp. 643-651
    • Folkman, J.1
  • 155
    • 11844254414 scopus 로고    scopus 로고
    • Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy
    • Jain RK: Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. Science 2005;307:58-62.
    • (2005) Science , vol.307 , pp. 58-62
    • Jain, R.K.1
  • 156
    • 68249143439 scopus 로고    scopus 로고
    • Hurwitz H, Fehrenbacher L, Cartwright T, Hainsworth J, Heim W, Berlin J, Griffing S, Novotny W, Holmgren E, Kabbinavar F: Bevacizumab (a monoclonal antibody to vascular endothelial growth factor) prolongs survival in first-line colorectal cancer (CRC): results of a phase III trial of bevacizumab in combination with bolus IFL (irinotecan, 5-fluorouracil, leucovorin) as first-line therapy in subjects with metastatic CRC. Abstracts ASCO, 2003.
    • Hurwitz H, Fehrenbacher L, Cartwright T, Hainsworth J, Heim W, Berlin J, Griffing S, Novotny W, Holmgren E, Kabbinavar F: Bevacizumab (a monoclonal antibody to vascular endothelial growth factor) prolongs survival in first-line colorectal cancer (CRC): results of a phase III trial of bevacizumab in combination with bolus IFL (irinotecan, 5-fluorouracil, leucovorin) as first-line therapy in subjects with metastatic CRC. Abstracts ASCO, 2003.
  • 157
    • 2942590261 scopus 로고    scopus 로고
    • Vascular endothelial growth factor as a target for anticancer therapy
    • Ferrara N: Vascular endothelial growth factor as a target for anticancer therapy Oncologist 2004;9(suppl 1):2-10.
    • (2004) Oncologist , vol.9 , Issue.SUPPL. 1 , pp. 2-10
    • Ferrara, N.1
  • 158
    • 7444224685 scopus 로고    scopus 로고
    • Integrating the anti-VEGF-A humanized monoclonal antibody bevaci-zumab with chemotherapy in advanced colorectal cancer
    • Hurwitz H: Integrating the anti-VEGF-A humanized monoclonal antibody bevaci-zumab with chemotherapy in advanced colorectal cancer. Clin Colorectal Cancer 2004;4(suppl 2):S62-S68.
    • (2004) Clin Colorectal Cancer , vol.4 , Issue.SUPPL. 2
    • Hurwitz, H.1
  • 160
    • 34548316976 scopus 로고    scopus 로고
    • Molecular basis for sunitinib efficacy and future clinical development
    • Faivre S, Demetri G, Sargent W, Raymond E: Molecular basis for sunitinib efficacy and future clinical development. Nat Rev Drug Discov 2007;6:734-745.
    • (2007) Nat Rev Drug Discov , vol.6 , pp. 734-745
    • Faivre, S.1    Demetri, G.2    Sargent, W.3    Raymond, E.4
  • 162
    • 17144385138 scopus 로고    scopus 로고
    • Randomized comparison of low-molecular-weight heparin and coumarin derivatives on the survival of patients with cancer and venous thromboembolism
    • Lee AY, Rickles FR, Julian JA, Gent M, Baker RI, Bowden C, Kakkar AK, Prins M, Levine MN: Randomized comparison of low-molecular-weight heparin and coumarin derivatives on the survival of patients with cancer and venous thromboembolism. J Clin Oncol 2005;23:2123-2129.
    • (2005) J Clin Oncol , vol.23 , pp. 2123-2129
    • Lee, A.Y.1    Rickles, F.R.2    Julian, J.A.3    Gent, M.4    Baker, R.I.5    Bowden, C.6    Kakkar, A.K.7    Prins, M.8    Levine, M.N.9
  • 165
    • 0000348593 scopus 로고    scopus 로고
    • Requirement for binding of catalytically active factor VIIa in tissue factor-dependent experimental metastasis
    • Mueller BM, Ruf W: Requirement for binding of catalytically active factor VIIa in tissue factor-dependent experimental metastasis. J Clin Invest 1998;101:1372-1378.
    • (1998) J Clin Invest , vol.101 , pp. 1372-1378
    • Mueller, B.M.1    Ruf, W.2
  • 167
    • 33746092472 scopus 로고    scopus 로고
    • Ex vivo and in vivo delivery of anti-tissue factor short interfering RNA inhibits mouse pulmonary metastasis of B16 melanoma cells
    • Amarzguioui M, Peng Q, Wiiger MT, Vasovic V, Babaie E, Holen T, Nesland JM, Prydz H: Ex vivo and in vivo delivery of anti-tissue factor short interfering RNA inhibits mouse pulmonary metastasis of B16 melanoma cells. Clin Cancer Res 2006;12:4055-4061.
    • (2006) Clin Cancer Res , vol.12 , pp. 4055-4061
    • Amarzguioui, M.1    Peng, Q.2    Wiiger, M.T.3    Vasovic, V.4    Babaie, E.5    Holen, T.6    Nesland, J.M.7    Prydz, H.8
  • 169
    • 12244289602 scopus 로고    scopus 로고
    • A paradigm for therapy-induced microenvironmental changes in solid tumors leading to drug resistance
    • Yu JL, Coomber BL, Kerbel RS: A paradigm for therapy-induced microenvironmental changes in solid tumors leading to drug resistance. Differentiation 2002;70:599-609.
    • (2002) Differentiation , vol.70 , pp. 599-609
    • Yu, J.L.1    Coomber, B.L.2    Kerbel, R.S.3
  • 170
    • 30444436766 scopus 로고    scopus 로고
    • The principal eosinophil peroxidase product, HOSCN, is a uniquely potent phagocyte oxidant inducer of endothelial cell tissue factor activity: A potential mechanism for thrombosis in eosinophilic inflammatory states
    • Wang JG, Mahmud SA, Thompson JA, Geng JG, Key NS, Slungaard A: The principal eosinophil peroxidase product, HOSCN, is a uniquely potent phagocyte oxidant inducer of endothelial cell tissue factor activity: a potential mechanism for thrombosis in eosinophilic inflammatory states. Blood 2006;107:558-565.
    • (2006) Blood , vol.107 , pp. 558-565
    • Wang, J.G.1    Mahmud, S.A.2    Thompson, J.A.3    Geng, J.G.4    Key, N.S.5    Slungaard, A.6
  • 171
    • 21844455249 scopus 로고    scopus 로고
    • Procoagulant-soluble tissue factor is released from endothelial cells in response to inflammatory cytokines
    • Szotowski B, Antoniak S, Poller W, Schultheiss HP, Rauch U: Procoagulant-soluble tissue factor is released from endothelial cells in response to inflammatory cytokines. Circ Res 2005;96:1233-1239.
    • (2005) Circ Res , vol.96 , pp. 1233-1239
    • Szotowski, B.1    Antoniak, S.2    Poller, W.3    Schultheiss, H.P.4    Rauch, U.5
  • 172
    • 0035122535 scopus 로고    scopus 로고
    • Effect of intradermal tumor necrosis factor-α-induced inflammation on coagulation factors in dermal vessel endothelium. An in vivo study of human skin biopsies
    • Speiser W, Kapiotis S, Kopp CW, Simonitsch I, Jilma B, Jansen B, Exner M, Chott A: Effect of intradermal tumor necrosis factor-α-induced inflammation on coagulation factors in dermal vessel endothelium. An in vivo study of human skin biopsies. Thromb Haemost 2001;85:362-367.
    • (2001) Thromb Haemost , vol.85 , pp. 362-367
    • Speiser, W.1    Kapiotis, S.2    Kopp, C.W.3    Simonitsch, I.4    Jilma, B.5    Jansen, B.6    Exner, M.7    Chott, A.8
  • 173
    • 0032975660 scopus 로고    scopus 로고
    • Cooperation between VEGF and TNF-alpha;is necessary for exposure of active tissue factor on the surface of human endothelial cells
    • Camera M, Giesen PL, Fallon J, Aufiero BM, Taubman M, Tremoli E, Nemerson Y Cooperation between VEGF and TNF-alpha;is necessary for exposure of active tissue factor on the surface of human endothelial cells. Arterioscler Thromb Vasc Biol 1999;19:531-537.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 531-537
    • Camera, M.1    Giesen, P.L.2    Fallon, J.3    Aufiero, B.M.4    Taubman, M.5    Tremoli, E.6    Nemerson, Y.7
  • 174
    • 0030605839 scopus 로고    scopus 로고
    • Synergistic induction of endothelial tissue factor by tumor necrosis factor and vascular endothelial growth factor: Functional analysis of the tumor necrosis factor receptors
    • Clauss M, Grell M, Fangmann C, Fiers W, Scheurich P, Risau W: Synergistic induction of endothelial tissue factor by tumor necrosis factor and vascular endothelial growth factor: functional analysis of the tumor necrosis factor receptors. FEBS Lett 1996;390:334-338.
    • (1996) FEBS Lett , vol.390 , pp. 334-338
    • Clauss, M.1    Grell, M.2    Fangmann, C.3    Fiers, W.4    Scheurich, P.5    Risau, W.6
  • 175
    • 0029966652 scopus 로고    scopus 로고
    • Regulation of tissue factor gene expression in human monocytic and endothelial cells
    • Mackman N: Regulation of tissue factor gene expression in human monocytic and endothelial cells. Haemostasis 1996;26 (suppl 1):17-19.
    • (1996) Haemostasis , vol.26 , Issue.SUPPL. 1 , pp. 17-19
    • Mackman, N.1
  • 177
    • 0029033973 scopus 로고
    • Transcriptional regulation of tissue factor expression in human endothelial cells
    • Parry GC, Mackman N: Transcriptional regulation of tissue factor expression in human endothelial cells. Arterioscler Thromb Vasc Biol 1995;15: 612-621.
    • (1995) Arterioscler Thromb Vasc Biol , vol.15 , pp. 612-621
    • Parry, G.C.1    Mackman, N.2
  • 178
    • 0028926427 scopus 로고
    • Regulation of the tissue factor promoter in endothelial cells. Binding of NF-κB-, AP-1-, and Sp1-like transcription factors
    • Moll T, Czyz M, Holzmuller H, Hofer-Warbinek R, Wagner E, Winkler H, Bach FH, Hofer E: Regulation of the tissue factor promoter in endothelial cells. Binding of NF-κB-, AP-1-, and Sp1-like transcription factors. J Biol Chem 1995;270: 3849-3857.
    • (1995) J Biol Chem , vol.270 , pp. 3849-3857
    • Moll, T.1    Czyz, M.2    Holzmuller, H.3    Hofer-Warbinek, R.4    Wagner, E.5    Winkler, H.6    Bach, F.H.7    Hofer, E.8
  • 179
    • 0022601049 scopus 로고
    • Modulation of endothelial cell hemostatic properties by tumor necrosis factor
    • Nawroth PP, Stern DM: Modulation of endothelial cell hemostatic properties by tumor necrosis factor. J Exp Med 1986;163: 740-745.
    • (1986) J Exp Med , vol.163 , pp. 740-745
    • Nawroth, P.P.1    Stern, D.M.2
  • 180
    • 0000555820 scopus 로고
    • Recombinant tumor necrosis factor induces procoagulant activity in cultured human vascular endothelium: Characterization and comparison with the actions of interleukin-1
    • Bevilacqua MP, Pober JS, Majeau GR, Fiers W, Cotran RS, Gimbrone MA Jr: Recombinant tumor necrosis factor induces procoagulant activity in cultured human vascular endothelium: characterization and comparison with the actions of interleukin-1. Proc Natl Acad Sci USA 1986;83:4533-4537.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 4533-4537
    • Bevilacqua, M.P.1    Pober, J.S.2    Majeau, G.R.3    Fiers, W.4    Cotran, R.S.5    Gimbrone Jr, M.A.6
  • 181
    • 0035469890 scopus 로고    scopus 로고
    • Lipopolysaccharide activation of the MEK-ERK1/2 pathway in human monocytic cells mediates tissue factor and tumor necrosis factor- αexpression by inducing Elk-1 phosphorylation and Egr-1 expression
    • Guha M, O'Connell MA, Pawlinski R, Hollis A, McGovern P, Yan SF, Stern D, Mackman N: Lipopolysaccharide activation of the MEK-ERK1/2 pathway in human monocytic cells mediates tissue factor and tumor necrosis factor- αexpression by inducing Elk-1 phosphorylation and Egr-1 expression. Blood 2001;98: 1429-1439.
    • (2001) Blood , vol.98 , pp. 1429-1439
    • Guha, M.1    O'Connell, M.A.2    Pawlinski, R.3    Hollis, A.4    McGovern, P.5    Yan, S.F.6    Stern, D.7    Mackman, N.8
  • 183
    • 0028270180 scopus 로고
    • Expression of tissue factor and tissue factor pathway inhibitor in monocytes in response to bacterial lipopolysaccharide and phorbol ester
    • Van der Logt CP, Dirven RJ, Reitsma PH, Bertina RM: Expression of tissue factor and tissue factor pathway inhibitor in monocytes in response to bacterial lipopolysaccharide and phorbol ester. Blood Coagul Fibrinolysis 1994;5:211-220.
    • (1994) Blood Coagul Fibrinolysis , vol.5 , pp. 211-220
    • Van der Logt, C.P.1    Dirven, R.J.2    Reitsma, P.H.3    Bertina, R.M.4
  • 184
    • 0023694658 scopus 로고
    • Tumor necrosis factor induces tissue factor-like activity in human leukemia cell line U937 and peripheral blood monocytes
    • Conkling PR, Greenberg CS, Weinberg JB: Tumor necrosis factor induces tissue factor-like activity in human leukemia cell line U937 and peripheral blood monocytes. Blood 1988;72: 128-133.
    • (1988) Blood , vol.72 , pp. 128-133
    • Conkling, P.R.1    Greenberg, C.S.2    Weinberg, J.B.3
  • 185
    • 0033790858 scopus 로고    scopus 로고
    • Cytokines and hemostasis
    • Grignani G, Maiolo A: Cytokines and hemostasis. Haematologica 2000;85:967-972.
    • (2000) Haematologica , vol.85 , pp. 967-972
    • Grignani, G.1    Maiolo, A.2
  • 187
    • 0033152286 scopus 로고    scopus 로고
    • Vascular endothelial cell growth factor-induced tissue factor expression in endothelial cells is mediated by EGR-1
    • Mechtcheriakova D, Wlachos A, Holzmuller H, Binder BR, Hofer E: Vascular endothelial cell growth factor-induced tissue factor expression in endothelial cells is mediated by EGR-1. Blood 1999;93:3811-3823.
    • (1999) Blood , vol.93 , pp. 3811-3823
    • Mechtcheriakova, D.1    Wlachos, A.2    Holzmuller, H.3    Binder, B.R.4    Hofer, E.5
  • 188
    • 0032473560 scopus 로고    scopus 로고
    • Vascular endothelial growth factor induces tissue factor and matrix metalloproteinase production in endothelial cells: Conversion of prothrombin to thrombin results in progelatinase A activation and cell proliferation
    • Zucker S, Mirza H, Conner CE, Lorenz AF, Drews MH, Bahou WF, Jesty J: Vascular endothelial growth factor induces tissue factor and matrix metalloproteinase production in endothelial cells: conversion of prothrombin to thrombin results in progelatinase A activation and cell proliferation. Int J Cancer 1998;75:780-786.
    • (1998) Int J Cancer , vol.75 , pp. 780-786
    • Zucker, S.1    Mirza, H.2    Conner, C.E.3    Lorenz, A.F.4    Drews, M.H.5    Bahou, W.F.6    Jesty, J.7
  • 189
    • 0029929716 scopus 로고    scopus 로고
    • The vascular endothelial growth factor receptor Flt-1 mediates biological activities. Implications for a functional role of placenta growth factor in monocyte activation and chemotaxis
    • Clauss M, Weich H, Breier G, Knies U, Rockl W, Waltenberger J, Risau W: The vascular endothelial growth factor receptor Flt-1 mediates biological activities. Implications for a functional role of placenta growth factor in monocyte activation and chemotaxis. J Biol Chem 1996;271:17629-17634.
    • (1996) J Biol Chem , vol.271 , pp. 17629-17634
    • Clauss, M.1    Weich, H.2    Breier, G.3    Knies, U.4    Rockl, W.5    Waltenberger, J.6    Risau, W.7
  • 190
    • 0025875990 scopus 로고
    • The structural biology of expression and function of tissue factor
    • Edgington TS, Mackman N, Brand K, Ruf W: The structural biology of expression and function of tissue factor. Thromb Haemost 1991;66:67-79.
    • (1991) Thromb Haemost , vol.66 , pp. 67-79
    • Edgington, T.S.1    Mackman, N.2    Brand, K.3    Ruf, W.4
  • 191
    • 0030722998 scopus 로고    scopus 로고
    • Up-regulation of tissue factor expression by platelet-derived growth factor in human vascular smooth muscle cells in culture-role of mitogen-activated protein kinase and effects of intracellular cyclic AMP
    • Xuereb JM, Sie P, Boneu B, Constans J: Up-regulation of tissue factor expression by platelet-derived growth factor in human vascular smooth muscle cells in culture-role of mitogen-activated protein kinase and effects of intracellular cyclic AMP. Thromb Haemost 1997;78:1520-1526.
    • (1997) Thromb Haemost , vol.78 , pp. 1520-1526
    • Xuereb, J.M.1    Sie, P.2    Boneu, B.3    Constans, J.4
  • 192
    • 0029100932 scopus 로고
    • Regulation of the tissue factor gene
    • Mackman N: Regulation of the tissue factor gene. FASEB J 1995;9:883-889.
    • (1995) FASEB J , vol.9 , pp. 883-889
    • Mackman, N.1
  • 193
    • 0028175558 scopus 로고
    • Regulation of tissue factor gene expression in epithelial cells. Induction by serum and phorbol 12-myristate 13-acetate
    • Cui MZ, Parry GC, Edgington TS, Mackman N: Regulation of tissue factor gene expression in epithelial cells. Induction by serum and phorbol 12-myristate 13-acetate. Arterioscler Thromb 1994;14:807-814.
    • (1994) Arterioscler Thromb , vol.14 , pp. 807-814
    • Cui, M.Z.1    Parry, G.C.2    Edgington, T.S.3    Mackman, N.4
  • 194
    • 0026752981 scopus 로고
    • Induction of tissue factor activity in endothelial cells and monocytes by a modified form of albumin present in normal human plasma
    • Faucette KJ, Parker CJ, McCluskey T, Bernshaw NJ, Rodgers GM: Induction of tissue factor activity in endothelial cells and monocytes by a modified form of albumin present in normal human plasma. Blood 1992;79:2888-2895.
    • (1992) Blood , vol.79 , pp. 2888-2895
    • Faucette, K.J.1    Parker, C.J.2    McCluskey, T.3    Bernshaw, N.J.4    Rodgers, G.M.5
  • 195
    • 22144486974 scopus 로고    scopus 로고
    • Modulation of tissue factor expression by rapamycin and FK-506 in lipopolysaccharide- stimulated human mononuclear cells and serum-stimulated aortic smooth muscle cells
    • Ollivier V, Hammal S, Ameziane N, Labro MT, de Prost D: Modulation of tissue factor expression by rapamycin and FK-506 in lipopolysaccharide- stimulated human mononuclear cells and serum-stimulated aortic smooth muscle cells. Thromb Haemost 2005;94:46-52.
    • (2005) Thromb Haemost , vol.94 , pp. 46-52
    • Ollivier, V.1    Hammal, S.2    Ameziane, N.3    Labro, M.T.4    de Prost, D.5
  • 196
    • 0033933597 scopus 로고    scopus 로고
    • Inhibition of tissue factor synthesis by disruption of ERK kinases and PKC signaling pathways in human vascular SMCs
    • Xuereb JM, Sie P, Boneu B, Constans J: Inhibition of tissue factor synthesis by disruption of ERK kinases and PKC signaling pathways in human vascular SMCs. Thromb Haemost 2000;84:129-136.
    • (2000) Thromb Haemost , vol.84 , pp. 129-136
    • Xuereb, J.M.1    Sie, P.2    Boneu, B.3    Constans, J.4
  • 197
    • 0029155572 scopus 로고
    • Tissue factor gene transcription in serum-stimulated fibroblasts is mediated by recruitment of c-Fos into specific AP-1 DNA-binding complexes
    • Felts SJ, Stoflet ES, Eggers CT, Getz MJ: Tissue factor gene transcription in serum-stimulated fibroblasts is mediated by recruitment of c-Fos into specific AP-1 DNA-binding complexes. Biochemistry 1995;34:12355-12362.
    • (1995) Biochemistry , vol.34 , pp. 12355-12362
    • Felts, S.J.1    Stoflet, E.S.2    Eggers, C.T.3    Getz, M.J.4
  • 198
    • 0024507992 scopus 로고
    • Serum stimulation of quiescent human fi-broblasts induces the synthesis of tissue factor m R NA fol lowed by t he appea r a nce of tissue factor antigen and procoagulant activity
    • Bloem LJ, Chen L, Konigsberg WH, Bach R: Serum stimulation of quiescent human fi-broblasts induces the synthesis of tissue factor m R NA fol lowed by t he appea r a nce of tissue factor antigen and procoagulant activity. J Cell Physiol 1989;139:418-423.
    • (1989) J Cell Physiol , vol.139 , pp. 418-423
    • Bloem, L.J.1    Chen, L.2    Konigsberg, W.H.3    Bach, R.4
  • 201
    • 33645730645 scopus 로고    scopus 로고
    • The serum- and glucocorticoid-inducible kinase Sgk-1 is involved in pulmonary vascular remodeling: Role in redox-sensitive regulation of tissue factor by thrombin
    • BelAiba RS, Djordjevic T, Bonello S, Artunc F, Lang F, Hess J, Gorlach A: The serum- and glucocorticoid-inducible kinase Sgk-1 is involved in pulmonary vascular remodeling: role in redox-sensitive regulation of tissue factor by thrombin. Circ Res 2006;98:828-836.
    • (2006) Circ Res , vol.98 , pp. 828-836
    • BelAiba, R.S.1    Djordjevic, T.2    Bonello, S.3    Artunc, F.4    Lang, F.5    Hess, J.6    Gorlach, A.7
  • 202
    • 20444507176 scopus 로고    scopus 로고
    • Thrombin activates the p21-activated kinase in pulmonary artery smooth muscle cells. Role in tissue factor expression
    • Gorlach A, BelAiba RS, Hess J, Kietzmann T: Thrombin activates the p21-activated kinase in pulmonary artery smooth muscle cells. Role in tissue factor expression. Thromb Haemost 2005;93:1168-1175.
    • (2005) Thromb Haemost , vol.93 , pp. 1168-1175
    • Gorlach, A.1    BelAiba, R.S.2    Hess, J.3    Kietzmann, T.4
  • 203
    • 3042782829 scopus 로고    scopus 로고
    • Rac regulates thrombin-induced tissue factor expression in pulmonary artery smooth muscle cells involving the nuclear factor-κB pathway
    • Djordjevic T, Hess J, Herkert O, Gorlach A, BelAiba RS: Rac regulates thrombin-induced tissue factor expression in pulmonary artery smooth muscle cells involving the nuclear factor-κB pathway. Antioxid Redox Signal 2004;6:713-720.
    • (2004) Antioxid Redox Signal , vol.6 , pp. 713-720
    • Djordjevic, T.1    Hess, J.2    Herkert, O.3    Gorlach, A.4    BelAiba, R.S.5
  • 205
    • 0037067676 scopus 로고    scopus 로고
    • Induction of tissue factor expression in human endothelial cells by CD40 ligand is mediated via activator protein 1, nuclear factor-κB, and Egr-1
    • Bavendiek U, Libby P, Kilbride M, Reynolds R, Mackman N, Schonbeck U: Induction of tissue factor expression in human endothelial cells by CD40 ligand is mediated via activator protein 1, nuclear factor-κB, and Egr-1. J Biol Chem 2002;277:25032-25039.
    • (2002) J Biol Chem , vol.277 , pp. 25032-25039
    • Bavendiek, U.1    Libby, P.2    Kilbride, M.3    Reynolds, R.4    Mackman, N.5    Schonbeck, U.6
  • 208
    • 35048852484 scopus 로고    scopus 로고
    • Microparticles from apoptotic monocytes induce transient platelet recruitment and tissue factor expression by cultured human vascular endothelial cells via a redox-sensitive mechanism
    • Essayagh S, Xuereb JM, Terrisse AD, Tellier-Cirioni L, Pipy B, Sie P: Microparticles from apoptotic monocytes induce transient platelet recruitment and tissue factor expression by cultured human vascular endothelial cells via a redox-sensitive mechanism. Thromb Haemost 2007;98:831-837.
    • (2007) Thromb Haemost , vol.98 , pp. 831-837
    • Essayagh, S.1    Xuereb, J.M.2    Terrisse, A.D.3    Tellier-Cirioni, L.4    Pipy, B.5    Sie, P.6
  • 209
    • 3042812429 scopus 로고    scopus 로고
    • Hypochlorous acid, a macrophage product, induces endothelial apoptosis and tissue factor expression: Involvement of myeloperoxidase-mediated oxidant in plaque erosion and thrombogenesis
    • Sugiyama S, Kugiyama K, Aikawa M, Nakamura S, Ogawa H, Libby P: Hypochlorous acid, a macrophage product, induces endothelial apoptosis and tissue factor expression: involvement of myeloperoxidase-mediated oxidant in plaque erosion and thrombogenesis. Arterioscler Thromb Vasc Biol 2004;24:1309-1314.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 1309-1314
    • Sugiyama, S.1    Kugiyama, K.2    Aikawa, M.3    Nakamura, S.4    Ogawa, H.5    Libby, P.6
  • 210
    • 34548688681 scopus 로고    scopus 로고
    • Ionizing radiation induces upregulation of cellular procoagulability and tissue factor expression in human peripheral blood mononuclear cells
    • Goldin-Lang P, Niebergall F, Antoniak S, Szotowski B, Rosenthal P, Pels K, Schult-heiss HP, Rauch U: Ionizing radiation induces upregulation of cellular procoagulability and tissue factor expression in human peripheral blood mononuclear cells. Thromb Res 2007;120:857-864.
    • (2007) Thromb Res , vol.120 , pp. 857-864
    • Goldin-Lang, P.1    Niebergall, F.2    Antoniak, S.3    Szotowski, B.4    Rosenthal, P.5    Pels, K.6    Schult-heiss, H.P.7    Rauch, U.8
  • 211
    • 29244486444 scopus 로고    scopus 로고
    • Discrepancy between tissue factor activity and tissue factor expression in endotoxin-induced monocytes is associated with apoptosis and necrosis
    • Henriksson CE, Klingenberg O, Ovstebo R, Joo GB, Westvik AB, Kierulf P: Discrepancy between tissue factor activity and tissue factor expression in endotoxin-induced monocytes is associated with apoptosis and necrosis. Thromb Haemost 2005;94:1236-1244.
    • (2005) Thromb Haemost , vol.94 , pp. 1236-1244
    • Henriksson, C.E.1    Klingenberg, O.2    Ovstebo, R.3    Joo, G.B.4    Westvik, A.B.5    Kierulf, P.6
  • 212
    • 37649013951 scopus 로고    scopus 로고
    • Upregulation of tissue factor expression and thrombogenic activity in human aortic smooth muscle cells by irradiation, rapamycin and pacli-taxel
    • Eisenreich A, Celebi O, Goldin-Lang P, Schultheiss HP, Rauch U: Upregulation of tissue factor expression and thrombogenic activity in human aortic smooth muscle cells by irradiation, rapamycin and pacli-taxel. Int Immunopharmacol 2008;8:307-311.
    • (2008) Int Immunopharmacol , vol.8 , pp. 307-311
    • Eisenreich, A.1    Celebi, O.2    Goldin-Lang, P.3    Schultheiss, H.P.4    Rauch, U.5
  • 215
    • 15444379633 scopus 로고    scopus 로고
    • Thalidomide in the treatment of cancer cachexia: A randomised placebo-controlled trial
    • Gordon JN, Trebble TM, Ellis RD, Duncan HD, Johns T, Goggin PM: Thalidomide in the treatment of cancer cachexia: a randomised placebo-controlled trial. Gut 2005;54:540-545.
    • (2005) Gut , vol.54 , pp. 540-545
    • Gordon, J.N.1    Trebble, T.M.2    Ellis, R.D.3    Duncan, H.D.4    Johns, T.5    Goggin, P.M.6
  • 216
    • 0344928503 scopus 로고    scopus 로고
    • Analysis of prothrombotic mechanisms and endothelial perturbation during treatment with angiogenesis inhibitors
    • Kuenen BC: Analysis of prothrombotic mechanisms and endothelial perturbation during treatment with angiogenesis inhibitors. Pathophysiol Haemost Thromb 2003;33(suppl 1):13-14.
    • (2003) Pathophysiol Haemost Thromb , vol.33 , Issue.SUPPL. 1 , pp. 13-14
    • Kuenen, B.C.1
  • 217
    • 0025816430 scopus 로고
    • Selective induction of endothelial cell tissue factor in the presence of a tumour-derived mediator: A potential mechanism of flavone acetic acid action in tumour vasculature
    • Murray JC, Clauss M, Denekamp J, Stern D: Selective induction of endothelial cell tissue factor in the presence of a tumour-derived mediator: a potential mechanism of flavone acetic acid action in tumour vasculature. Int J Cancer 1991;49:254-259.
    • (1991) Int J Cancer , vol.49 , pp. 254-259
    • Murray, J.C.1    Clauss, M.2    Denekamp, J.3    Stern, D.4
  • 218
    • 0026476479 scopus 로고
    • Uptake of exogenous free cholesterol induces upregulation of tissue factor expression in human monocyte-derived macrophages
    • Lesnik P, Rouis M, Skarlatos S, Kruth HS, Chapman MJ: Uptake of exogenous free cholesterol induces upregulation of tissue factor expression in human monocyte-derived macrophages. Proc Natl Acad Sci USA 1992;89:10370-10374.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 10370-10374
    • Lesnik, P.1    Rouis, M.2    Skarlatos, S.3    Kruth, H.S.4    Chapman, M.J.5
  • 219
    • 3342941667 scopus 로고    scopus 로고
    • Aggregated low-density lipoprotein uptake induces membrane tissue factor procoagulant activity and microparticle release in human vascular smooth muscle cells
    • Llorente-Cortes V, Otero-Vinas M, Camino-Lopez S, Llampayas O, Badimon L: Aggregated low-density lipoprotein uptake induces membrane tissue factor procoagulant activity and microparticle release in human vascular smooth muscle cells. Circulation 2004;110:452-459.
    • (2004) Circulation , vol.110 , pp. 452-459
    • Llorente-Cortes, V.1    Otero-Vinas, M.2    Camino-Lopez, S.3    Llampayas, O.4    Badimon, L.5
  • 220
    • 18644361988 scopus 로고    scopus 로고
    • Involvement of p38 MAPK in the up-regulation of tissue factor on endothelial cells by antiphospholipid antibodies
    • Vega-Ostertag M, Casper K, Swerlick R, Ferrara D, Harris EN, Pierangeli SS: Involvement of p38 MAPK in the up-regulation of tissue factor on endothelial cells by antiphospholipid antibodies. Arthritis Rheum 2005;52:1545-1554.
    • (2005) Arthritis Rheum , vol.52 , pp. 1545-1554
    • Vega-Ostertag, M.1    Casper, K.2    Swerlick, R.3    Ferrara, D.4    Harris, E.N.5    Pierangeli, S.S.6
  • 221
    • 0027474773 scopus 로고
    • Induction of endothelial cell tissue factor activity by sera from patients with antiphospholipid syndrome: A possible mechanism of thrombosis
    • Branch DW, Rodgers GM: Induction of endothelial cell tissue factor activity by sera from patients with antiphospholipid syndrome: a possible mechanism of thrombosis. Am J Obstet Gy necol 1993;168:206-210.
    • (1993) Am J Obstet Gy necol , vol.168 , pp. 206-210
    • Branch, D.W.1    Rodgers, G.M.2
  • 222
    • 0024428169 scopus 로고
    • Synergistic effect of low doses of tumor necrosis factor and sera from patients with systemic lupus erythematosus on the expression of procoagulant activity by cultured endothelial cells
    • Hasselaar P, Derksen RH, Oosting JD, Blokzijl L, De Groot PG: Synergistic effect of low doses of tumor necrosis factor and sera from patients with systemic lupus erythematosus on the expression of procoagulant activity by cultured endothelial cells. Thromb Haemost 1989;62:654-660.
    • (1989) Thromb Haemost , vol.62 , pp. 654-660
    • Hasselaar, P.1    Derksen, R.H.2    Oosting, J.D.3    Blokzijl, L.4    De Groot, P.G.5
  • 223
    • 0022456313 scopus 로고
    • Antibody and immune complexes induce tissue factor production by human endothelial cells
    • Tannenbaum SH, Finko R, Cines DB: Antibody and immune complexes induce tissue factor production by human endothelial cells. J Immunol 1986;137:1532-1537.
    • (1986) J Immunol , vol.137 , pp. 1532-1537
    • Tannenbaum, S.H.1    Finko, R.2    Cines, D.B.3
  • 225
    • 0037902227 scopus 로고    scopus 로고
    • Tumoral angiogenesis and tissue factor expression during hepatocellular carcinoma progression in a transgenic mouse model
    • Dupuy E, Hainaud P, Villemain A, Bodevin-Phedre E, Brouland JP, Briand P, Tobelem G: Tumoral angiogenesis and tissue factor expression during hepatocellular carcinoma progression in a transgenic mouse model. J Hepatol 2003;38:793-802.
    • (2003) J Hepatol , vol.38 , pp. 793-802
    • Dupuy, E.1    Hainaud, P.2    Villemain, A.3    Bodevin-Phedre, E.4    Brouland, J.P.5    Briand, P.6    Tobelem, G.7
  • 226
    • 0029854237 scopus 로고    scopus 로고
    • Expression of tissue factor in tumor stroma correlates with progression to invasive human breast cancer: Paracrine regulation by carcinoma cell-derived members of the transforming growth factor-βfamily
    • Vrana JA, Stang MT, Grande JP, Getz MJ: Expression of tissue factor in tumor stroma correlates with progression to invasive human breast cancer: paracrine regulation by carcinoma cell-derived members of the transforming growth factor-βfamily. Cancer Res 1996;56:5063-5070.
    • (1996) Cancer Res , vol.56 , pp. 5063-5070
    • Vrana, J.A.1    Stang, M.T.2    Grande, J.P.3    Getz, M.J.4
  • 227
    • 0026775867 scopus 로고
    • Immuno-histochemical identification of tissue factor in solid tumors
    • Callander NS, Varki N, Rao LV: Immuno-histochemical identification of tissue factor in solid tumors. Cancer 1992;70:1194-1201.
    • (1992) Cancer , vol.70 , pp. 1194-1201
    • Callander, N.S.1    Varki, N.2    Rao, L.V.3
  • 228
    • 0025218720 scopus 로고
    • A polypeptide factor produced by fibrosarcoma cells that induces endothelial tissue factor and enhances the procoagulant response to tumor necrosis factor/cachectin
    • Clauss M, Murray JC, Vianna M, de Waal R, Thurston G, Nawroth P, Gerlach H, Bach R, Familletti PC, Stern D: A polypeptide factor produced by fibrosarcoma cells that induces endothelial tissue factor and enhances the procoagulant response to tumor necrosis factor/cachectin. J Biol Chem 1990;265:7078-7083.
    • (1990) J Biol Chem , vol.265 , pp. 7078-7083
    • Clauss, M.1    Murray, J.C.2    Vianna, M.3    de Waal, R.4    Thurston, G.5    Nawroth, P.6    Gerlach, H.7    Bach, R.8    Familletti, P.C.9    Stern, D.10
  • 229
    • 0031756985 scopus 로고    scopus 로고
    • Tissue factor expression by monocytes: Regulation and pathophysiological roles
    • Osterud B: Tissue factor expression by monocytes: regulation and pathophysiological roles. Blood Coagul Fibrinolysis 1998;9(suppl 1):S9-S14.
    • (1998) Blood Coagul Fibrinolysis , vol.9 , Issue.SUPPL. 1
    • Osterud, B.1
  • 231
    • 0032935334 scopus 로고    scopus 로고
    • The thrombophilic state induced by therapeutic agents in the cancer patient
    • Lee AY, Levine MN: The thrombophilic state induced by therapeutic agents in the cancer patient. Semin Thromb Hemost 1999;25:137-145.
    • (1999) Semin Thromb Hemost , vol.25 , pp. 137-145
    • Lee, A.Y.1    Levine, M.N.2
  • 232
    • 0028830795 scopus 로고
    • Coagulation activation by MC28 fibrosarcoma cells facilitates lung tumor formation
    • Amirkhosravi M, Francis JL: Coagulation activation by MC28 fibrosarcoma cells facilitates lung tumor formation. Thromb Haemost 1995;73:59-65.
    • (1995) Thromb Haemost , vol.73 , pp. 59-65
    • Amirkhosravi, M.1    Francis, J.L.2
  • 235
    • 0020961939 scopus 로고
    • Activation of blood coagulation in cancer: Trousseau's syndrome revisited
    • Rickles FR, Edwards RL: Activation of blood coagulation in cancer: Trousseau's syndrome revisited. Blood 1983;62:14-31.
    • (1983) Blood , vol.62 , pp. 14-31
    • Rickles, F.R.1    Edwards, R.L.2
  • 236
    • 0035260140 scopus 로고    scopus 로고
    • The role of the hemostatic system in tumor growth, metastasis, and angiogenesis: Tissue factor is a bi-functional molecule capable of inducing both fibrin deposition and angiogenesis in cancer
    • Rickles FR, Shoji M, Abe K: The role of the hemostatic system in tumor growth, metastasis, and angiogenesis: tissue factor is a bi-functional molecule capable of inducing both fibrin deposition and angiogenesis in cancer. Int J Hematol 2001;73:145-150.
    • (2001) Int J Hematol , vol.73 , pp. 145-150
    • Rickles, F.R.1    Shoji, M.2    Abe, K.3
  • 239
    • 0030020131 scopus 로고    scopus 로고
    • Tumor angiogenesis and tissue factor
    • Folkman J: Tumor angiogenesis and tissue factor. Nat Med 1996;2:167-168.
    • (1996) Nat Med , vol.2 , pp. 167-168
    • Folkman, J.1
  • 240
    • 31544450986 scopus 로고    scopus 로고
    • Protease-activated receptor-2 is essential for factor VIIa and Xa-induced signaling, migration, and invasion of breast cancer cells
    • Morris DR, Ding Y, Ricks TK, Gullapalli A, Wolfe BL, Trejo J: Protease-activated receptor-2 is essential for factor VIIa and Xa-induced signaling, migration, and invasion of breast cancer cells. Cancer Res 2006;66: 307-314.
    • (2006) Cancer Res , vol.66 , pp. 307-314
    • Morris, D.R.1    Ding, Y.2    Ricks, T.K.3    Gullapalli, A.4    Wolfe, B.L.5    Trejo, J.6
  • 241
    • 3342972815 scopus 로고    scopus 로고
    • Formation of tissue factor-factor VIIa-factor Xa complex promotes cellular signaling and migration of human breast cancer cells
    • Jiang X, Bailly MA, Panetti TS, Cappello M, Konigsberg WH, Bromberg ME: Formation of tissue factor-factor VIIa-factor Xa complex promotes cellular signaling and migration of human breast cancer cells. J Thromb Haemost 2004;2:93-101.
    • (2004) J Thromb Haemost , vol.2 , pp. 93-101
    • Jiang, X.1    Bailly, M.A.2    Panetti, T.S.3    Cappello, M.4    Konigsberg, W.H.5    Bromberg, M.E.6
  • 242
    • 1842474888 scopus 로고    scopus 로고
    • Tissue factor-factor VIIa-specific up-regulation of IL-8 expression in MDA-MB-231 cells is mediated by PAR-2 and results in increased cell migration
    • Hjortoe GM, Petersen LC, Albrektsen T, Sorensen BB, Norby PL, Mandal SK, Pen-durthi UR, Rao LV: Tissue factor-factor VIIa-specific up-regulation of IL-8 expression in MDA-MB-231 cells is mediated by PAR-2 and results in increased cell migration. Blood 2004;103:3029-3037.
    • (2004) Blood , vol.103 , pp. 3029-3037
    • Hjortoe, G.M.1    Petersen, L.C.2    Albrektsen, T.3    Sorensen, B.B.4    Norby, P.L.5    Mandal, S.K.6    Pen-durthi, U.R.7    Rao, L.V.8
  • 246
    • 0026029064 scopus 로고
    • Thrombin stimulates tumor-platelet adhesion in vitro and metastasis in vivo
    • Nierodzik ML, Plotkin A, Kajumo F, Karpatkin S: Thrombin stimulates tumor-platelet adhesion in vitro and metastasis in vivo. J Clin Invest 1991;87:229-236.
    • (1991) J Clin Invest , vol.87 , pp. 229-236
    • Nierodzik, M.L.1    Plotkin, A.2    Kajumo, F.3    Karpatkin, S.4
  • 247
    • 9144266359 scopus 로고    scopus 로고
    • An in vitro study on the mechanisms of coagulation activation in acute myelogenous leukemia: Role of tissue factor regulation by cytotoxic drugs and GM-CSF
    • Langer F, Amirkhosravi A, Loges S, Meyer T, Eifrig B, Hossfeld DK, Fiedler W, Francis JL: An in vitro study on the mechanisms of coagulation activation in acute myelogenous leukemia: role of tissue factor regulation by cytotoxic drugs and GM-CSF. Thromb Haemost 2004;92:1136-1146.
    • (2004) Thromb Haemost , vol.92 , pp. 1136-1146
    • Langer, F.1    Amirkhosravi, A.2    Loges, S.3    Meyer, T.4    Eifrig, B.5    Hossfeld, D.K.6    Fiedler, W.7    Francis, J.L.8
  • 248
    • 34548494139 scopus 로고    scopus 로고
    • Tissue factor coagulant function is enhanced by protein-disulfide isomerase independent of oxidore-ductase activity
    • Versteeg HH, Ruf W: Tissue factor coagulant function is enhanced by protein-disulfide isomerase independent of oxidore-ductase activity. J Biol Chem 2007;282: 25416-25424.
    • (2007) J Biol Chem , vol.282 , pp. 25416-25424
    • Versteeg, H.H.1    Ruf, W.2
  • 249
    • 33644557719 scopus 로고    scopus 로고
    • Emerging insights in tissue factor-dependent signaling events
    • Versteeg HH, Ruf W: Emerging insights in tissue factor-dependent signaling events. Semin Thromb Hemost 2006;32:24-32.
    • (2006) Semin Thromb Hemost , vol.32 , pp. 24-32
    • Versteeg, H.H.1    Ruf, W.2
  • 250
    • 13244273430 scopus 로고    scopus 로고
    • Impaired hemostasis and protection against thrombosis in protease-activated receptor 4-deficient mice is due to lack of thrombin signaling in platelets
    • Hamilton JR, Cornelissen I, Coughlin SR: Impaired hemostasis and protection against thrombosis in protease-activated receptor 4-deficient mice is due to lack of thrombin signaling in platelets. J Thromb Haemost 2004;2:1429-1435.
    • (2004) J Thromb Haemost , vol.2 , pp. 1429-1435
    • Hamilton, J.R.1    Cornelissen, I.2    Coughlin, S.R.3
  • 251
    • 33747122295 scopus 로고    scopus 로고
    • Formation of tissue factor-factor VIIa-factor Xa complex prevents apoptosis in human breast cancer cells
    • Jiang X, Guo YL, Bromberg ME: Formation of tissue factor-factor VIIa-factor Xa complex prevents apoptosis in human breast cancer cells. Thromb Haemost 2006;96: 196-201.
    • (2006) Thromb Haemost , vol.96 , pp. 196-201
    • Jiang, X.1    Guo, Y.L.2    Bromberg, M.E.3
  • 252
    • 0036332455 scopus 로고    scopus 로고
    • Protein expression profiles of non-small cell lung carcinomas: Correlation with histologica l subtype
    • Volm M, Koomagi R, Efferth T, Mattern J: Protein expression profiles of non-small cell lung carcinomas: correlation with histologica l subtype. Anticancer Res 2002;22: 2321-2324.
    • (2002) Anticancer Res , vol.22 , pp. 2321-2324
    • Volm, M.1    Koomagi, R.2    Efferth, T.3    Mattern, J.4
  • 253
    • 0036619633 scopus 로고    scopus 로고
    • The clinical value of measuring tissue factor activity in patients with cancer
    • Lwaleed BA: The clinical value of measuring tissue factor activity in patients with cancer. Med Hy potheses 2002;58:521-522.
    • (2002) Med Hy potheses , vol.58 , pp. 521-522
    • Lwaleed, B.A.1
  • 254
    • 34250706406 scopus 로고    scopus 로고
    • Cancer and thrombosis: From molecular mechanisms to clinical presentations
    • Buller HR, van Doormaal FF, van Sluis GL, Kamphuisen PW: Cancer and thrombosis: from molecular mechanisms to clinical presentations. J Thromb Haemost 2007;5(suppl 1):246-254.
    • (2007) J Thromb Haemost , vol.5 , Issue.SUPPL. 1 , pp. 246-254
    • Buller, H.R.1    van Doormaal, F.F.2    van Sluis, G.L.3    Kamphuisen, P.W.4
  • 257
    • 33645669938 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of nicotine's pro-angiogen-esis activity and its potential impact on cancer
    • Mousa S, Mousa SA: Cellular and molecular mechanisms of nicotine's pro-angiogen-esis activity and its potential impact on cancer. J Cell Biochem 2006;97:1370-1378.
    • (2006) J Cell Biochem , vol.97 , pp. 1370-1378
    • Mousa, S.1    Mousa, S.A.2
  • 258
    • 17144385138 scopus 로고    scopus 로고
    • Randomized comparison of low-molecular-weight heparin and coumarin derivatives on the survival of patients with cancer and venous thromboembolism
    • Lee AY, Rickles FR, Julian JA, Gent M, Baker RI, Bowden C, Kakkar AK, Prins M, Levine MN: Randomized comparison of low-molecular-weight heparin and coumarin derivatives on the survival of patients with cancer and venous thromboembolism. J Clin Oncol 2005;23:2123-2129.
    • (2005) J Clin Oncol , vol.23 , pp. 2123-2129
    • Lee, A.Y.1    Rickles, F.R.2    Julian, J.A.3    Gent, M.4    Baker, R.I.5    Bowden, C.6    Kakkar, A.K.7    Prins, M.8    Levine, M.N.9
  • 259
    • 25144496456 scopus 로고    scopus 로고
    • Low-molecular-weight heparin and survival in patients with malignant disease
    • Kakkar AK: Low-molecular-weight heparin and survival in patients with malignant disease. Cancer Control 2005;12(suppl 1): 22-30.
    • (2005) Cancer Control , vol.12 , Issue.SUPPL. 1 , pp. 22-30
    • Kakkar, A.K.1
  • 260
    • 2942676484 scopus 로고    scopus 로고
    • Low- and ultra-low-molecular-weight heparins
    • Kakkar AK: Low- and ultra-low-molecular-weight heparins. Best Pract Res Clin Haematol 2004;17:77-87.
    • (2004) Best Pract Res Clin Haematol , vol.17 , pp. 77-87
    • Kakkar, A.K.1
  • 262
    • 1842463681 scopus 로고    scopus 로고
    • Antimetastatic effect of tinza-parin, a low-molecular-weight heparin
    • Amirkhosravi A, Mousa SA, Amaya M, Francis JL: Antimetastatic effect of tinza-parin, a low-molecular-weight heparin. J Thromb Haemost 2003;1:1972-1976.
    • (2003) J Thromb Haemost , vol.1 , pp. 1972-1976
    • Amirkhosravi, A.1    Mousa, S.A.2    Amaya, M.3    Francis, J.L.4
  • 263
    • 0344066255 scopus 로고    scopus 로고
    • Targeting the endothelium in cancer- the importance of the interaction of hemostatic mechanisms and the vascular wall for tumor growth and angiogenesis
    • Rickles FR, Patierno SR, Fernandez PM: Targeting the endothelium in cancer- the importance of the interaction of hemostatic mechanisms and the vascular wall for tumor growth and angiogenesis. Pathophysiol Haemost Thromb 2003;33(suppl 1):1-4.
    • (2003) Pathophysiol Haemost Thromb , vol.33 , Issue.SUPPL. 1 , pp. 1-4
    • Rickles, F.R.1    Patierno, S.R.2    Fernandez, P.M.3
  • 265
    • 0030664735 scopus 로고    scopus 로고
    • Prevention of venous thromboembolism in cancer using low-molecular-weight heparins
    • Kakkar AK, Williamson RC: Prevention of venous thromboembolism in cancer using low-molecular-weight heparins. Haemostasis 1997;27(suppl 1):32-37.
    • (1997) Haemostasis , vol.27 , Issue.SUPPL. 1 , pp. 32-37
    • Kakkar, A.K.1    Williamson, R.C.2
  • 266
    • 0030704644 scopus 로고    scopus 로고
    • Treatment of thrombotic disorders in cancer patients
    • Levine M: Treatment of thrombotic disorders in cancer patients. Haemostasis 1997;27(suppl 1):38-43.
    • (1997) Haemostasis , vol.27 , Issue.SUPPL. 1 , pp. 38-43
    • Levine, M.1
  • 267
    • 0026521512 scopus 로고
    • The effect of warfarin and factor VII on tissue procoag-ulant activity and pulmonary seeding
    • Francis JL, Carty N, Amirkhosravi M, Loizidou M, Cooper A, Taylor I: The effect of warfarin and factor VII on tissue procoag-ulant activity and pulmonary seeding. Br J Cancer 1992;65:329-334.
    • (1992) Br J Cancer , vol.65 , pp. 329-334
    • Francis, J.L.1    Carty, N.2    Amirkhosravi, M.3    Loizidou, M.4    Cooper, A.5    Taylor, I.6
  • 268
    • 0026045094 scopus 로고
    • An anti-tissue factor monoclonal antibody which inhibits TFVI-Ia complex is a potent anticoagulant in plasma
    • Ruf W, Edgington TS: An anti-tissue factor monoclonal antibody which inhibits TFVI-Ia complex is a potent anticoagulant in plasma. Thromb Haemost 1991;66:529-533.
    • (1991) Thromb Haemost , vol.66 , pp. 529-533
    • Ruf, W.1    Edgington, T.S.2
  • 269
    • 0023788406 scopus 로고
    • Promotion of metastasis by a specific complex of coagulation factors may be independent of fibrin formation
    • McCulloch P, George WD: Promotion of metastasis by a specific complex of coagulation factors may be independent of fibrin formation. Br J Cancer 1988;58:158-162.
    • (1988) Br J Cancer , vol.58 , pp. 158-162
    • McCulloch, P.1    George, W.D.2
  • 271
    • 0020572581 scopus 로고
    • Angiogenesis inhibition and tumor regression caused by heparin or a heparin fragment in the presence of cortisone
    • Folkman J, Langer R, Linhardt RJ, Haudenschild C, Taylor S: Angiogenesis inhibition and tumor regression caused by heparin or a heparin fragment in the presence of cortisone. Science 1983;221:719-725.
    • (1983) Science , vol.221 , pp. 719-725
    • Folkman, J.1    Langer, R.2    Linhardt, R.J.3    Haudenschild, C.4    Taylor, S.5
  • 273
    • 13244299030 scopus 로고    scopus 로고
    • Hirudin ameliorates intestinal radiation toxicity in the rat: Support for thrombin inhibition as strategy to minimize side-effects after radiation therapy and as countermea-sure against radiation exposure
    • Wang J, Zheng H, Ou X, Albertson CM, Fink LM, Herbert JM, Hauer-Jensen M: Hirudin ameliorates intestinal radiation toxicity in the rat: support for thrombin inhibition as strategy to minimize side-effects after radiation therapy and as countermea-sure against radiation exposure. J Thromb Haemost 2004;2:2027-2035.
    • (2004) J Thromb Haemost , vol.2 , pp. 2027-2035
    • Wang, J.1    Zheng, H.2    Ou, X.3    Albertson, C.M.4    Fink, L.M.5    Herbert, J.M.6    Hauer-Jensen, M.7
  • 275
    • 13244278113 scopus 로고    scopus 로고
    • Inhibition of TF gene expression by antisense oligonucleotides in different cancer cell lines
    • Forster Y, Schwenzer B: Inhibition of TF gene expression by antisense oligonucleotides in different cancer cell lines. J Exp Ther Oncol 2004;4:281-289.
    • (2004) J Exp Ther Oncol , vol.4 , pp. 281-289
    • Forster, Y.1    Schwenzer, B.2
  • 277
    • 34047199255 scopus 로고    scopus 로고
    • Inflammatory mediators and nuclear receptor signaling in colorectal cancer
    • Wang D, DuBois RN: Inflammatory mediators and nuclear receptor signaling in colorectal cancer. Cell Cycle 2007;6:682-685.
    • (2007) Cell Cycle , vol.6 , pp. 682-685
    • Wang, D.1    DuBois, R.N.2
  • 279
    • 57749094106 scopus 로고    scopus 로고
    • Tissue factor regulation by epidermal growth factor receptor and epithelial-to-mesenchymal transitions: Effect on tumor initiation and angiogenesis
    • in press
    • Milsom CC, Yu JL, Mackman N, Micallef J, Anderson GM, Guha A, Rak J: Tissue factor regulation by epidermal growth factor receptor and epithelial-to-mesenchymal transitions: Effect on tumor initiation and angiogenesis. Cancer Res 2008, in press.
    • (2008) Cancer Res
    • Milsom, C.C.1    Yu, J.L.2    Mackman, N.3    Micallef, J.4    Anderson, G.M.5    Guha, A.6    Rak, J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.