메뉴 건너뛰기




Volumn 26, Issue 3, 2005, Pages 557-564

Methylation and inhibition of expression of uPA by the RAS oncogene: Divergence of growth control and invasion in breast cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

DNA BINDING PROTEIN; DNA METHYLTRANSFERASE 1; UROKINASE; DNA (CYTOSINE 5 ) METHYLTRANSFERASE 1; DNA (CYTOSINE 5) METHYLTRANSFERASE; DNA (CYTOSINE-5-)-METHYLTRANSFERASE 1; PRIMER DNA;

EID: 16244364806     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/bgi009     Document Type: Article
Times cited : (34)

References (30)
  • 1
    • 0034996039 scopus 로고    scopus 로고
    • The role of the plasminogen activation system in angiogenesis and metastasis
    • Rabbani, S.A. and Mazar, A.P. (2001) The role of the plasminogen activation system in angiogenesis and metastasis. Surg. Oncol. Clin. N. Am., 10, 393-415, x.
    • (2001) Surg. Oncol. Clin. N. Am. , vol.10 , pp. 393-415
    • Rabbani, S.A.1    Mazar, A.P.2
  • 2
    • 0038364216 scopus 로고    scopus 로고
    • The urokinase plasminogen activator system in cancer: Recent advances and implication for prognosis and therapy
    • Sidenius, N. and Blasi, F. (2003) The urokinase plasminogen activator system in cancer: recent advances and implication for prognosis and therapy. Cancer Metastasis Rev., 22, 205-222.
    • (2003) Cancer Metastasis Rev. , vol.22 , pp. 205-222
    • Sidenius, N.1    Blasi, F.2
  • 3
    • 0031660713 scopus 로고    scopus 로고
    • Prognostic significance of stromelysin 3, gelatinase a and urokinase expression in breast cancer
    • Tetu, B., Brisson, J., Lapointe, H. and Bernard, P. (1998) Prognostic significance of stromelysin 3, gelatinase A and urokinase expression in breast cancer. Hum. Pathol., 29, 979-985.
    • (1998) Hum. Pathol. , vol.29 , pp. 979-985
    • Tetu, B.1    Brisson, J.2    Lapointe, H.3    Bernard, P.4
  • 4
    • 0035576006 scopus 로고    scopus 로고
    • Expression of cathepsin D, stromelysin-3 and urokinase by reactive stromal cells on breast carcinoma prognosis
    • Tetu, B., Brisson, J., Wang, C.S., Lapointe, H., Beaudry, G. and Blanchette, C. (2001) Expression of cathepsin D, stromelysin-3 and urokinase by reactive stromal cells on breast carcinoma prognosis. Cancer, 92, 2957-2964.
    • (2001) Cancer , vol.92 , pp. 2957-2964
    • Tetu, B.1    Brisson, J.2    Wang, C.S.3    Lapointe, H.4    Beaudry, G.5    Blanchette, C.6
  • 5
    • 2442602305 scopus 로고    scopus 로고
    • Demethylation of urokinase promoter as a prognostic marker in patients with breast carcinoma
    • Pakneshan, P., Tetu, B. and Rabbani, S.A. (2004) Demethylation of urokinase promoter as a prognostic marker in patients with breast carcinoma. Clin. Cancer Res., 10, 3035-3041.
    • (2004) Clin. Cancer Res. , vol.10 , pp. 3035-3041
    • Pakneshan, P.1    Tetu, B.2    Rabbani, S.A.3
  • 6
    • 0036830198 scopus 로고    scopus 로고
    • Regulation of DNA methylation in human breast cancer. Effect on the urokinase-type plasminogen activator gene production and tumor invasion
    • Guo, Y., Pakneshan, P., Gladu, J., Slack, A., Szyf, M. and Rabbani, S.A. (2002) Regulation of DNA methylation in human breast cancer. Effect on the urokinase-type plasminogen activator gene production and tumor invasion. J. Biol. Chem., 277, 41571-41579.
    • (2002) J. Biol. Chem. , vol.277 , pp. 41571-41579
    • Guo, Y.1    Pakneshan, P.2    Gladu, J.3    Slack, A.4    Szyf, M.5    Rabbani, S.A.6
  • 7
    • 0036274359 scopus 로고    scopus 로고
    • The fundamental role of epigenetic events in cancer
    • Jones, P.A. and Baylin, S.B. (2002) The fundamental role of epigenetic events in cancer. Nature Rev. Genet., 3, 415-428.
    • (2002) Nature Rev. Genet. , vol.3 , pp. 415-428
    • Jones, P.A.1    Baylin, S.B.2
  • 9
    • 3843125363 scopus 로고    scopus 로고
    • Reversal of the hypomethylation status of urokinase (uPA) promoter blocks breast cancer growth and metastasis
    • Pakneshan, P., Szyf, M., Farias-Eisner, R. and Rabbani, S.A. (2004) Reversal of the hypomethylation status of urokinase (uPA) promoter blocks breast cancer growth and metastasis. J. Biol. Chem., 279, 31735-31744.
    • (2004) J. Biol. Chem. , vol.279 , pp. 31735-31744
    • Pakneshan, P.1    Szyf, M.2    Farias-Eisner, R.3    Rabbani, S.A.4
  • 10
    • 0037264633 scopus 로고    scopus 로고
    • Targeting RAS signalling pathways in cancer therapy
    • Downward, J. (2003) Targeting RAS signalling pathways in cancer therapy. Nature Rev. Cancer, 3, 11-22.
    • (2003) Nature Rev. Cancer , vol.3 , pp. 11-22
    • Downward, J.1
  • 11
    • 0035908493 scopus 로고    scopus 로고
    • Blocking oncogenic Ras signaling for cancer therapy
    • Adjei, A.A. (2001) Blocking oncogenic Ras signaling for cancer therapy. J. Natl Cancer Inst., 93, 1062-1074.
    • (2001) J. Natl Cancer Inst. , vol.93 , pp. 1062-1074
    • Adjei, A.A.1
  • 12
    • 0028925009 scopus 로고
    • Regulation of the DNA methyltransferase by the Ras-AP-1 signaling pathway
    • Rouleau, J., MacLeod, A.R. and Szyf, M. (1995) Regulation of the DNA methyltransferase by the Ras-AP-1 signaling pathway. J. Biol. Chem., 270, 1595-1601.
    • (1995) J. Biol. Chem. , vol.270 , pp. 1595-1601
    • Rouleau, J.1    MacLeod, A.R.2    Szyf, M.3
  • 13
    • 0029046134 scopus 로고
    • Regulation of DNA methylation by the Ras signaling pathway
    • MacLeod, A.R., Rouleau, J. and Szyf, M. (1995) Regulation of DNA methylation by the Ras signaling pathway. J. Biol. Chem., 270, 11327-11337.
    • (1995) J. Biol. Chem. , vol.270 , pp. 11327-11337
    • MacLeod, A.R.1    Rouleau, J.2    Szyf, M.3
  • 14
    • 0033973226 scopus 로고    scopus 로고
    • Transcriptional regulation of the human DNA methyltransferase (dnmt1) gene
    • Bigey, P., Ramchandani, S., Theberge, J., Araujo, F.D. and Szyf, M. (2000) Transcriptional regulation of the human DNA methyltransferase (dnmt1) gene. Gene, 242, 407-418.
    • (2000) Gene , vol.242 , pp. 407-418
    • Bigey, P.1    Ramchandani, S.2    Theberge, J.3    Araujo, F.D.4    Szyf, M.5
  • 15
    • 0026061569 scopus 로고
    • Localization of urokinase-type plasminogen activator in stromal cells in adenocarcinomas of the colon in humans
    • Grondahl-Hansen, J., Ralfkiaer, E., Kirkeby, L.T., Kristensen, P., Lund, L.R. and Dano, K. (1991) Localization of urokinase-type plasminogen activator in stromal cells in adenocarcinomas of the colon in humans. Am. J. Pathol., 138, 111-117.
    • (1991) Am. J. Pathol. , vol.138 , pp. 111-117
    • Grondahl-Hansen, J.1    Ralfkiaer, E.2    Kirkeby, L.T.3    Kristensen, P.4    Lund, L.R.5    Dano, K.6
  • 16
    • 0037709969 scopus 로고    scopus 로고
    • Methylation status of uPA promoter as a molecular mechanism regulating prostate cancer invasion and growth in vitro and in vivo
    • Pakneshan, P., Xing, R.H. and Rabbani, S.A. (2003) Methylation status of uPA promoter as a molecular mechanism regulating prostate cancer invasion and growth in vitro and in vivo. FASEB J., 17, 1081-1088.
    • (2003) FASEB J. , vol.17 , pp. 1081-1088
    • Pakneshan, P.1    Xing, R.H.2    Rabbani, S.A.3
  • 19
    • 0025767987 scopus 로고
    • Induction of glutathione content in murine melanocytes after transformation with c-H-ras oncogene
    • Thrall, B.D. and Meadows, G.G. (1991) Induction of glutathione content in murine melanocytes after transformation with c-H-ras oncogene. Carcinogenesis, 12, 1319-1323.
    • (1991) Carcinogenesis , vol.12 , pp. 1319-1323
    • Thrall, B.D.1    Meadows, G.G.2
  • 20
    • 0024548165 scopus 로고
    • Malignant transformation of human fibroblasts caused by expression of a transfected T24 HRAS oncogene
    • Hurlin, P.J., Maher, V.M. and McCormick, J.J. (1989) Malignant transformation of human fibroblasts caused by expression of a transfected T24 HRAS oncogene. Proc. Natl Acad. Sci. USA, 86, 187-191.
    • (1989) Proc. Natl Acad. Sci. USA , vol.86 , pp. 187-191
    • Hurlin, P.J.1    Maher, V.M.2    McCormick, J.J.3
  • 21
    • 0034054673 scopus 로고    scopus 로고
    • DNA methyltransferase inhibition induces the transcription of the tumor suppressor p21 (WAF1/CIP1/sdi1)
    • Milutinovic, S., Knox, J.D. and Szyf, M. (2000) DNA methyltransferase inhibition induces the transcription of the tumor suppressor p21 (WAF1/CIP1/sdi1). J. Biol. Chem., 275, 6353-6359.
    • (2000) J. Biol. Chem. , vol.275 , pp. 6353-6359
    • Milutinovic, S.1    Knox, J.D.2    Szyf, M.3
  • 22
    • 0035798693 scopus 로고    scopus 로고
    • Demethylase activity is directed by histone acetylation
    • Cervoni, N. and Szyf, M. (2001) Demethylase activity is directed by histone acetylation. J. Biol. Chem., 276, 40778-40787.
    • (2001) J. Biol. Chem. , vol.276 , pp. 40778-40787
    • Cervoni, N.1    Szyf, M.2
  • 23
    • 0025015368 scopus 로고
    • Cis modification of the steroid 21-hydroxylase gene prevents its expression in the Y1 mouse adrenocortical tumor cell line
    • Szyf, M., Milstone, D.S., Schimmer, B.P., Parker, K.L. and Seidman, J.G. (1990) cis modification of the steroid 21-hydroxylase gene prevents its expression in the Y1 mouse adrenocortical tumor cell line. Mol. Endocrinol., 4, 1144-1152.
    • (1990) Mol. Endocrinol. , vol.4 , pp. 1144-1152
    • Szyf, M.1    Milstone, D.S.2    Schimmer, B.P.3    Parker, K.L.4    Seidman, J.G.5
  • 24
    • 0026439115 scopus 로고
    • A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei
    • Leonhardt, H., Page, A.W., Weier, H.U. and Bestor, T.H. (1992) A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei. Cell, 71, 865-873.
    • (1992) Cell , vol.71 , pp. 865-873
    • Leonhardt, H.1    Page, A.W.2    Weier, H.U.3    Bestor, T.H.4
  • 25
    • 0029973718 scopus 로고    scopus 로고
    • De novo methylation of CpG island sequences in human fibroblasts overexpressing DNA (cytosine-5-)-methyltransferase
    • Vertino, P.M., Yen, R.W., Gao, J. and Baylin, S.B. (1996) De novo methylation of CpG island sequences in human fibroblasts overexpressing DNA (cytosine-5-)-methyltransferase. Mol. Cell. Biol., 16, 4555-4565.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 4555-4565
    • Vertino, P.M.1    Yen, R.W.2    Gao, J.3    Baylin, S.B.4
  • 26
    • 0037068358 scopus 로고    scopus 로고
    • Reactivating the expression of methylation silenced genes in human cancer
    • Karpf, A.R. and Jones, D.A. (2002) Reactivating the expression of methylation silenced genes in human cancer. Oncogene, 21, 5496-5503.
    • (2002) Oncogene , vol.21 , pp. 5496-5503
    • Karpf, A.R.1    Jones, D.A.2
  • 27
    • 1042278765 scopus 로고    scopus 로고
    • The history of cancer epigenetics
    • Feinberg, A.P. and Tycko, B. (2004) The history of cancer epigenetics. Nature Rev. Cancer, 4, 143-153.
    • (2004) Nature Rev. Cancer , vol.4 , pp. 143-153
    • Feinberg, A.P.1    Tycko, B.2
  • 28
    • 0032468051 scopus 로고    scopus 로고
    • Hypomethylation of the metastasis-associated S100A4 gene correlates with gene activation in human colon adenocarcinoma cell lines
    • Nakamura, N. and Takenaga, K. (1998) Hypomethylation of the metastasis-associated S100A4 gene correlates with gene activation in human colon adenocarcinoma cell lines. Clin. Exp. Metastasis, 16, 471-479.
    • (1998) Clin. Exp. Metastasis , vol.16 , pp. 471-479
    • Nakamura, N.1    Takenaga, K.2
  • 29
    • 0033565976 scopus 로고    scopus 로고
    • Deregulation of the signaling pathways controlling urokinase production. Its relationship with the invasive phenotype
    • Aguirre Ghiso, J.A., Alonso, D.F., Farias, E.F., Gomez, D.E. and de Kier Joffe, E.B. (1999) Deregulation of the signaling pathways controlling urokinase production. Its relationship with the invasive phenotype. Eur. J. Biochem., 263, 295-304.
    • (1999) Eur. J. Biochem. , vol.263 , pp. 295-304
    • Aguirre Ghiso, J.A.1    Alonso, D.F.2    Farias, E.F.3    Gomez, D.E.4    De Kier Joffe, E.B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.