-
1
-
-
33748445698
-
Malignancy and Hemostasis
-
Coleman RB, Marder VJ, Clowes AW, George JN, Goldhaber SZ, eds, Philadelphia: Lippincott Company Williams & Wilkins
-
Dvorak FH, Rickles FR. Malignancy and Hemostasis. In: Coleman RB, Marder VJ, Clowes AW, George JN, Goldhaber SZ, eds. Hemostasis and Thrombosis: Basic Principles and Clinical Practice. Philadelphia: Lippincott Company Williams & Wilkins. 2006:851-873.
-
(2006)
Hemostasis and Thrombosis: Basic Principles and Clinical Practice
, pp. 851-873
-
-
Dvorak, F.H.1
Rickles, F.R.2
-
2
-
-
33748454321
-
Mechanisms of cancer-induced thrombosis in cancer
-
Rickles FR. Mechanisms of cancer-induced thrombosis in cancer. Pathophysiol Haemost Thromb. 2006;35:103-110.
-
(2006)
Pathophysiol Haemost Thromb
, vol.35
, pp. 103-110
-
-
Rickles, F.R.1
-
3
-
-
0027935431
-
Tissue factor controls the balance of angiogenic and anti-angiogenic properties of tumor cells in mice
-
Zhang Y, Deng Y, Luther T, Muller M, Ziegler R, Waldherr R, Stern DM, Nawroth PP. Tissue factor controls the balance of angiogenic and anti-angiogenic properties of tumor cells in mice. J Clin Invest. 1994;94:1320-1327.
-
(1994)
J Clin Invest
, vol.94
, pp. 1320-1327
-
-
Zhang, Y.1
Deng, Y.2
Luther, T.3
Muller, M.4
Ziegler, R.5
Waldherr, R.6
Stern, D.M.7
Nawroth, P.P.8
-
4
-
-
0037567437
-
Tissue factor/factor VIIa inhibitors block angiogenesis and tumor growth through a nonhemostatic mechanism
-
Hembrough TA, Swartz GM, Papathanassiu A, Vlasuk GP, Rote WE, Green SG, Pribluda VS. Tissue factor/factor VIIa inhibitors block angiogenesis and tumor growth through a nonhemostatic mechanism. Cancer Res. 2003;63;2997-3000.
-
(2003)
Cancer Res
, vol.63
, pp. 2997-3000
-
-
Hembrough, T.A.1
Swartz, G.M.2
Papathanassiu, A.3
Vlasuk, G.P.4
Rote, W.E.5
Green, S.G.6
Pribluda, V.S.7
-
5
-
-
33846950031
-
CNTO 859, a humanized anti-tissue factor monoclonal antibody, is a potent inhibitor of breast cancer metastasis and tumor growth in xenograft models
-
Ngo CV, Picha K, McCabe F et al. CNTO 859, a humanized anti-tissue factor monoclonal antibody, is a potent inhibitor of breast cancer metastasis and tumor growth in xenograft models. Int J Cancer. 2007;120:1261-1267.
-
(2007)
Int J Cancer
, vol.120
, pp. 1261-1267
-
-
Ngo, C.V.1
Picha, K.2
McCabe, F.3
-
6
-
-
13544256266
-
Oncogenic events regulate tissue factor expression in colorectal cancer cells: Implications for tumor progression and angiogenesis
-
Yu JL, May L, Lhotak V, Shahrzad, Shirasawa S, Weitz JI, Coomber BL, Mackman N, Rak JW. Oncogenic events regulate tissue factor expression in colorectal cancer cells: implications for tumor progression and angiogenesis. Blood. 2005;105:1734-1741.
-
(2005)
Blood
, vol.105
, pp. 1734-1741
-
-
Yu, J.L.1
May, L.2
Lhotak, V.3
Shahrzad4
Shirasawa, S.5
Weitz, J.I.6
Coomber, B.L.7
Mackman, N.8
Rak, J.W.9
-
7
-
-
0031010407
-
Effect of tissue factor deficiency on mouse and tumor development
-
Toomey JR, Kratzer KE, Lasky NM, Broze GJ, Jr. Effect of tissue factor deficiency on mouse and tumor development. Proc Natl Acad Sci U S A. 1997;94:6922-6926.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 6922-6926
-
-
Toomey, J.R.1
Kratzer, K.E.2
Lasky, N.M.3
Broze Jr., G.J.4
-
8
-
-
34347385401
-
Tumor cell-associated tissue factor and circulating hemostatic factors cooperate to increase metastatic potential through natural killer cell-dependent and-independent mechanisms
-
Palumbo JS, Talmage KE, Massari JV, LaJeunesse CM, Flick MJ, Kombrinck KW, Jarouskova M, Degen JL. Tumor cell-associated tissue factor and circulating hemostatic factors cooperate to increase metastatic potential through natural killer cell-dependent and-independent mechanisms. Blood. 2007;110:133-141.
-
(2007)
Blood
, vol.110
, pp. 133-141
-
-
Palumbo, J.S.1
Talmage, K.E.2
Massari, J.V.3
LaJeunesse, C.M.4
Flick, M.J.5
Kombrinck, K.W.6
Jarouskova, M.7
Degen, J.L.8
-
9
-
-
0030020590
-
In situ detection of tissue factor in vascular endothelial cells: Correlation with the malignant phenotype of human breast disease
-
Contrino J, Hair G, Kreutzer DL, Rickles FR. In situ detection of tissue factor in vascular endothelial cells: correlation with the malignant phenotype of human breast disease. Nat Med. 1996;2:209-215.
-
(1996)
Nat Med
, vol.2
, pp. 209-215
-
-
Contrino, J.1
Hair, G.2
Kreutzer, D.L.3
Rickles, F.R.4
-
10
-
-
0141819106
-
Tissue factor, thrombin, and cancer
-
Rickles FR, Patierno S, Fernandez PM. Tissue factor, thrombin, and cancer. Chest. 2003;124:58S-68S.
-
(2003)
Chest
, vol.124
-
-
Rickles, F.R.1
Patierno, S.2
Fernandez, P.M.3
-
11
-
-
34447644229
-
Redundant signaling of tissue factor and thrombin in cancer progression?
-
Ruf W. Redundant signaling of tissue factor and thrombin in cancer progression? J Thromb Haemost. 2007;5:1584-1587.
-
(2007)
J Thromb Haemost
, vol.5
, pp. 1584-1587
-
-
Ruf, W.1
-
12
-
-
28344436780
-
Protease-activated receptors in hemostasis, thrombosis and vascular biology
-
Coughlin SR. Protease-activated receptors in hemostasis, thrombosis and vascular biology. J Thromb Haemost. 2005;3:1800-1814.
-
(2005)
J Thromb Haemost
, vol.3
, pp. 1800-1814
-
-
Coughlin, S.R.1
-
13
-
-
34547630092
-
Role of the extrinsic pathway of blood coagulation in hemostasis and thrombosis
-
Mackman N, Tilley RE, Key NS. Role of the extrinsic pathway of blood coagulation in hemostasis and thrombosis. Arterioscler Thromb Vasc Biol. 2007;27:1687-93.
-
(2007)
Arterioscler Thromb Vasc Biol
, vol.27
, pp. 1687-1693
-
-
Mackman, N.1
Tilley, R.E.2
Key, N.S.3
-
14
-
-
2442700125
-
Regulation of angio-genesis by tissue factor cytoplasmic domain signaling
-
Belting M, Dorrell MI, Sandgren S, Aquilar E, Ahamed J, Dorfleutner A, Carmeliet P, Mueller BM, Friedlander M, Ruf W. Regulation of angio-genesis by tissue factor cytoplasmic domain signaling. Nat Med. 2004;10:502-509.
-
(2004)
Nat Med
, vol.10
, pp. 502-509
-
-
Belting, M.1
Dorrell, M.I.2
Sandgren, S.3
Aquilar, E.4
Ahamed, J.5
Dorfleutner, A.6
Carmeliet, P.7
Mueller, B.M.8
Friedlander, M.9
Ruf, W.10
-
16
-
-
0032006548
-
Low levels of tissue factor are compatible with development and hemostasis in mice
-
Parry GC, Erlich JH, Carmeliet P, Luther T, Mackman N. Low levels of tissue factor are compatible with development and hemostasis in mice. J Clin Invest. 1998;101:560-569.
-
(1998)
J Clin Invest
, vol.101
, pp. 560-569
-
-
Parry, G.C.1
Erlich, J.H.2
Carmeliet, P.3
Luther, T.4
Mackman, N.5
-
17
-
-
0027092617
-
Expression and functional activity of P-glycoprotein in cultured cerebral capillary endothelial cells
-
Hegmann EJ, Bauer HC, Kerbel RS. Expression and functional activity of P-glycoprotein in cultured cerebral capillary endothelial cells. Cancer Res. 1992;52:6969-6975.
-
(1992)
Cancer Res
, vol.52
, pp. 6969-6975
-
-
Hegmann, E.J.1
Bauer, H.C.2
Kerbel, R.S.3
-
18
-
-
35348892537
-
Atherosclerosis and vascular aging as modifiers of tumor progression, angiogenesis, and responsiveness to therapy
-
Klement H, St Croix B, Milsom C, May LJ, Guo Q, Yu JL, Klement P, Rak J. Atherosclerosis and vascular aging as modifiers of tumor progression, angiogenesis, and responsiveness to therapy. Am J Pathol. 2007;171:1342-1351.
-
(2007)
Am J Pathol
, vol.171
, pp. 1342-1351
-
-
Klement, H.1
St Croix, B.2
Milsom, C.3
May, L.J.4
Guo, Q.5
Yu, J.L.6
Klement, P.7
Rak, J.8
-
19
-
-
25444449494
-
Oncogenes and angiogenesis: Down-regulation of thrombospondin-1 in normal fibroblasts exposed to factors from cancer cells harboring mutant Ras
-
Kalas W, Yu JL, Milsom C, Rosenfeld J, Benezra R, Bornstein P, Rak J. Oncogenes and angiogenesis: down-regulation of thrombospondin-1 in normal fibroblasts exposed to factors from cancer cells harboring mutant Ras. Cancer Res. 2005;65:8878-8886.
-
(2005)
Cancer Res
, vol.65
, pp. 8878-8886
-
-
Kalas, W.1
Yu, J.L.2
Milsom, C.3
Rosenfeld, J.4
Benezra, R.5
Bornstein, P.6
Rak, J.7
-
20
-
-
0035069527
-
Heterogeneous vascular dependence of tumor cell populations
-
Yu JL, Rak JW, Carmeliet P, Nagy A, Kerbel RS, Coomber BL. Heterogeneous vascular dependence of tumor cell populations. Am J Pathol. 2001;158:1325-1334.
-
(2001)
Am J Pathol
, vol.158
, pp. 1325-1334
-
-
Yu, J.L.1
Rak, J.W.2
Carmeliet, P.3
Nagy, A.4
Kerbel, R.S.5
Coomber, B.L.6
-
21
-
-
0242331613
-
Thrombospondin 1, a mediator of the antiangiogenic effects of low-dose metronomic chemotherapy
-
Bocci G, Francia G, Man S, Lawler J, Kerbel RS. Thrombospondin 1, a mediator of the antiangiogenic effects of low-dose metronomic chemotherapy. Proc Natl Acad Sci U S A. 2003;100:12917-12922.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 12917-12922
-
-
Bocci, G.1
Francia, G.2
Man, S.3
Lawler, J.4
Kerbel, R.S.5
-
22
-
-
0025964244
-
Differential influence of organ site on three subpopulations of a single mouse mammary tumor at two distinct steps in metastasis
-
Aslakson CJ, Rak JW, Miller BE, Miller FR. Differential influence of organ site on three subpopulations of a single mouse mammary tumor at two distinct steps in metastasis. Int J Cancer. 1991;47:466-472.
-
(1991)
Int J Cancer
, vol.47
, pp. 466-472
-
-
Aslakson, C.J.1
Rak, J.W.2
Miller, B.E.3
Miller, F.R.4
-
23
-
-
0042967959
-
Contrasting effects of VEGF gene disruption in embryonic stem cell-derived versus oncogene-induced tumors
-
Viloria-Petit A, Miquerol L, Yu JL, Gertsenstein M, Sheehan C, May L, Henkin J, Lobe C, Nagy A, Kerbel RS, Rak J. Contrasting effects of VEGF gene disruption in embryonic stem cell-derived versus oncogene-induced tumors. EMBO J. 2003;22:4091-4102.
-
(2003)
EMBO J
, vol.22
, pp. 4091-4102
-
-
Viloria-Petit, A.1
Miquerol, L.2
Yu, J.L.3
Gertsenstein, M.4
Sheehan, C.5
May, L.6
Henkin, J.7
Lobe, C.8
Nagy, A.9
Kerbel, R.S.10
Rak, J.11
-
24
-
-
45849118364
-
Treatment of endothelium with the chemotherapy drug vincristine affects protein C generation in newborn plasma to a greater degree than in adult plasma
-
Mewhort-Buist TA, Liaw P, Patel S, Atkinson HM, Berry LR, Chan AK. Treatment of endothelium with the chemotherapy drug vincristine affects protein C generation in newborn plasma to a greater degree than in adult plasma. Thromb Res. 2008;122:418-426.
-
(2008)
Thromb Res
, vol.122
, pp. 418-426
-
-
Mewhort-Buist, T.A.1
Liaw, P.2
Patel, S.3
Atkinson, H.M.4
Berry, L.R.5
Chan, A.K.6
-
25
-
-
0035213197
-
Embryonic stem cell-derived embryoid bodies development in collagen gels recapitulates sprouting angiogenesis
-
Feraud O, Cao Y, Vittet D. Embryonic stem cell-derived embryoid bodies development in collagen gels recapitulates sprouting angiogenesis. Lab Invest. 2001;81:1669-1681.
-
(2001)
Lab Invest
, vol.81
, pp. 1669-1681
-
-
Feraud, O.1
Cao, Y.2
Vittet, D.3
-
26
-
-
0038143145
-
Vasculogenic mimicry and tumour-cell plasticity: Lessons from melanoma
-
Hendrix MJ, Seftor EA, Hess AR, Seftor RE. Vasculogenic mimicry and tumour-cell plasticity: lessons from melanoma. Nat Rev Cancer. 2003;3:411-421.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 411-421
-
-
Hendrix, M.J.1
Seftor, E.A.2
Hess, A.R.3
Seftor, R.E.4
-
27
-
-
13044304178
-
Blood-borne tissue factor: Another view of thrombosis
-
Giesen PL, Rauch U, Bohrmann B, Kling D, Rogue M, Fallon JT, Badimon JJ, Himber J, Riederer MA, Nemerson Y. Blood-borne tissue factor: another view of thrombosis. Proc Natl Acad Sci U S A. 1999;96:2311-2315.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 2311-2315
-
-
Giesen, P.L.1
Rauch, U.2
Bohrmann, B.3
Kling, D.4
Rogue, M.5
Fallon, J.T.6
Badimon, J.J.7
Himber, J.8
Riederer, M.A.9
Nemerson, Y.10
-
28
-
-
13244271290
-
Shedding of tissue factor (TF)-containing microparticles rather than alternatively spliced TF is the main source of TF activity released from human cancer cells
-
Yu JL, Rak JW. Shedding of tissue factor (TF)-containing microparticles rather than alternatively spliced TF is the main source of TF activity released from human cancer cells. J Thromb Haemost. 2004;2:2065-2067.
-
(2004)
J Thromb Haemost
, vol.2
, pp. 2065-2067
-
-
Yu, J.L.1
Rak, J.W.2
-
29
-
-
23944509766
-
Tissue-factor-bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation
-
Del Conde I, Shrimpton CN, Thiagarajan P, Lopez JA. Tissue-factor-bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation. Blood. 2005;106:1604-1611.
-
(2005)
Blood
, vol.106
, pp. 1604-1611
-
-
Del Conde, I.1
Shrimpton, C.N.2
Thiagarajan, P.3
Lopez, J.A.4
-
30
-
-
13044277569
-
Regulation of vascular endothelial growth factor production and angiogenesis by the cytoplasmic tail of tissue factor
-
Abe K, Shoji M, Chen J, Bierhaus A, Danave I, Micko C, Casper K, Dillehay DL, Nawroth PP, Rickles FR et al. Regulation of vascular endothelial growth factor production and angiogenesis by the cytoplasmic tail of tissue factor. Proc Natl Acad Sci U S A. 1999;96:8663-8668.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 8663-8668
-
-
Abe, K.1
Shoji, M.2
Chen, J.3
Bierhaus, A.4
Danave, I.5
Micko, C.6
Casper, K.7
Dillehay, D.L.8
Nawroth, P.P.9
Rickles, F.R.10
-
31
-
-
55949128845
-
Abo A rNAPc2, a novel inhibitor of tissue factor/factor VIIa complex, suppresses lung metastasis and synergizes with 5-FU or bevacizumab in mouse models of colorectal cancer [abstract]
-
Zhao J, Aguilar G, Deitcher SR, Funk WD. Abo A rNAPc2, a novel inhibitor of tissue factor/factor VIIa complex, suppresses lung metastasis and synergizes with 5-FU or bevacizumab in mouse models of colorectal cancer [abstract]. Blood 2006;108:321.
-
(2006)
Blood
, vol.108
, pp. 321
-
-
Zhao, J.1
Aguilar, G.2
Deitcher, S.R.3
Funk, W.D.4
-
32
-
-
38049101163
-
Inhibition of tissue factor signaling suppresses tumor growth
-
Versteeg HH, Schaffner F, Kerver M, Petersen HH, Ahamed J, Felding-Habermann B, Takada Y, Mueller BM, Ruf W. Inhibition of tissue factor signaling suppresses tumor growth. Blood. 2008;111:190-199.
-
(2008)
Blood
, vol.111
, pp. 190-199
-
-
Versteeg, H.H.1
Schaffner, F.2
Kerver, M.3
Petersen, H.H.4
Ahamed, J.5
Felding-Habermann, B.6
Takada, Y.7
Mueller, B.M.8
Ruf, W.9
-
33
-
-
36349006372
-
Elevated tissue factor procoagulant activity in CD133-positive cancer cells
-
Milsom C, Anderson GM, Weitz JI, Rak J. Elevated tissue factor procoagulant activity in CD133-positive cancer cells. J Thromb Haemost. 2007;5:2550-2552.
-
(2007)
J Thromb Haemost
, vol.5
, pp. 2550-2552
-
-
Milsom, C.1
Anderson, G.M.2
Weitz, J.I.3
Rak, J.4
-
34
-
-
0023818427
-
The thrombogenic effect of anticancer drug therapy in women with stage II breast cancer
-
Levine MN, Gent M, Hirsh J, Arnold A, Goodyear MD, Hryniuk W, DePauw S. The thrombogenic effect of anticancer drug therapy in women with stage II breast cancer. N Engl J Med. 1988;318:404-407.
-
(1988)
N Engl J Med
, vol.318
, pp. 404-407
-
-
Levine, M.N.1
Gent, M.2
Hirsh, J.3
Arnold, A.4
Goodyear, M.D.5
Hryniuk, W.6
DePauw, S.7
-
35
-
-
0036738403
-
Analysis of coagulation cascade and endothelial cell activation during inhibition of vascular endothelial growth factor/vascular endothelial growth factor receptor pathway in cancer patients
-
Kuenen BC, Levi M, Meijers JC, Kakkar AK, Van Hinsbergh VW, Kostense PJ, Pinedo HM, Hoekman K. Analysis of coagulation cascade and endothelial cell activation during inhibition of vascular endothelial growth factor/vascular endothelial growth factor receptor pathway in cancer patients. Arterioscler Thromb Vasc Biol. 2002;22:1500-1505.
-
(2002)
Arterioscler Thromb Vasc Biol
, vol.22
, pp. 1500-1505
-
-
Kuenen, B.C.1
Levi, M.2
Meijers, J.C.3
Kakkar, A.K.4
Van Hinsbergh, V.W.5
Kostense, P.J.6
Pinedo, H.M.7
Hoekman, K.8
-
36
-
-
34249294557
-
Possible molecular mechanisms involved in the toxicity of angiogenesis inhibition
-
Verheul HM, Pinedo HM. Possible molecular mechanisms involved in the toxicity of angiogenesis inhibition. Nat Rev Cancer. 2007;7:475-485.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 475-485
-
-
Verheul, H.M.1
Pinedo, H.M.2
-
37
-
-
20444433198
-
In vitro procoagulant activity induced in endothelial cells by chemotherapy and antiangiogenic drug combinations: Modulation by lower-dose chemotherapy
-
Ma L, Francia G, Viloria-Petit A, Hicklin D, du Manoir J, Rak J, Kerbel RS. In vitro procoagulant activity induced in endothelial cells by chemotherapy and antiangiogenic drug combinations: modulation by lower-dose chemotherapy. Cancer Res. 2005;65:5365-5373.
-
(2005)
Cancer Res
, vol.65
, pp. 5365-5373
-
-
Ma, L.1
Francia, G.2
Viloria-Petit, A.3
Hicklin, D.4
du Manoir, J.5
Rak, J.6
Kerbel, R.S.7
|