Tissue factor-factor VIIa-specific up-regulation of IL-8 expression in MDA-MB-231 cells is mediated by PAR-2 and results in increased cell migration

Blood

Volumn 103, Issue 8, 2004, Pages 3029-3037

  Hjortoe, Gertrud M ^b   Petersen, Lars C ^b   Albrektsen, Tatjana ^b   Sorensen, Brit B ^b   Norby, Peder L ^b   Manda, Samir K ^b   Pendurthi, Usha R ^b   Rao, L Vijaya Mohan ^a  

^a UNIVERSITY OF TEXAS HEALTH CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 7A; CHEMOKINE; INTERLEUKIN 8; PROTEINASE ACTIVATED RECEPTOR 2; THROMBOPLASTIN;

ANIMAL CELL; ANTIBODY SPECIFICITY; ARTICLE; BLOOD CLOTTING; BREAST CARCINOMA; CANCER INVASION; CELL MIGRATION; GENE; GENE EXPRESSION REGULATION; HEMOSTASIS; IL8 GENE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; TISSUE REPAIR; TISSUE SPECIFICITY; TRANSCRIPTION REGULATION;

EID: 1842474888     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2003-10-3417     Document Type: Article

References (77)

1. Trousseau A. Phlegmasia alba dolens: clinique medicale de l'Hotel-Dieu de Paris. The New Sydenham Society. 1865;3:654-712.
2. Sack GH, Levin J, Bell WR. Trousseau's syndrome and other manifestations at chronic disseminated coagulopathy in patients with neoplasms: clinical, pathophysiologic, and therapeutic teatures. Medicine. 1977;56:1-37.
3. Lieberman JS, Borrero J, Urdaneta E, Wright IS. Thrombophlebitis and cancer. JAMA. 1961;177:542-545.
4. Fisher MM, Hochberg LA, Wilensky ND. Recur rent thrombophlebitis on obscure malignant tumors at lung: report at tour cases. JAMA. 1951;147:1213-1216.
5. Perlow S, Daniels JL. Venous thrombosis and obscure visceral carcinoma: report at ten cases. Arch Intern Med. 1956;97:184-188.
6. Callander, NS, Varki N, Rao LVM. Immunohistochemical identification of tissue factor in solid tumors. Cancer, 1992;70:1194-1201.
7. Rao LVM. Tissue factor as a tumor procoagulant. Cancer Metastasis Rev. 1992;11:249-266
8. Shigemori C, Wada H, Matsumoto K, et al. Tissue taclor expression and metastatic potential of colorectal cancer. Thromb Haemost. 1998;80:894-898.
9. Kakkar AK, Lemoine NR, Scully MF, Tebbutt S, Williamson RC. Tissue factor expression correlates with histological grade in human pancreatic cancer. Br J Surg. 1995;82:1101-1104.
10. Hamada K, Kuratsu J, Saitoh Y, Nishi T, Ushio Y. Expression of tissue factor expression correlates with grade of malignancy in human glioma. Cancer. 1996;77:1877-1883.
11. Mueller BM, Reisleld RA, Edgington TS, Rut W. Expression of tissue factor by melanoma cells promotes efficient hematogenous metastasis. Proc Natl Acad Sci U S A. 1992;89:11832-11836.
12. Bromberg ME, Konigsberg WH, Madison JF, Pawashe A, Garen A. Tissue factor promotes melanoma metastasis by a pathway independent of blood coagulation. Proc Natl Acad Sci U S A. 1995;92:8205-8209.
13. Mueller BM, Rul W. Requirement for binding of catalytically active factor VIIa in tissue factor-dependent experimental metastasis. J Clin Invest. 1998;101:1372-1378.
14. Bromberg ME, Sundaram R, Homer RJ, Garen A, Konigsberg WH. Role of tissue factor in metastasis: functions of the cytoplasmic and extracellular domains of the molecule. Thromb Haemost. 1999;82:88-92.
15. Ott I, Fischer EG, Miyagi Y, Mueller BM, Rut W. A role for tissue factor in cell adhesion and migration mediated by interaction with actin-binding protein 280. J Cell Biol. 1998;140:1241-1253.
16. Nierodzik ML, Plotkin A, Kajumo F, Karpatkin S. Thrombin stimulates tumor-platelet adhesion in vitro and metastasis in vivo. J Clin Invest. 1991;87:229-236.
17. Fischer EG, Ruf W, Mueller BM. Tissue factor-initiated thrombin generation activates the signalling thrombin receptor on malignant melanoma cells. Cancer Res. 1995;55:1629-1632.
18. Hernandez-Rodriguez NA, Correa E, Contreras-Paredes A, Green L. Evidence that thrombin present in lungs of patients with pulmonary metastasis may contribute to the development of the disease. Lung Cancer. 1999;26:157-167.
19. Prydz HS, Camerer E, Rottingen J-A, Wiiger MT, Gjernes E. Cellular consequences of the initiation of blood coagulation. Thromb Haemost. 1999;82:183-192.
20. Pendurthi UR, Rao LVM. Factor VIIa/tissue factor-induced signaling: a link between clotting and disease. In: Litwick G, ed. Vitamins and Hormones. San Diego, CA: Academic Press; 2002:323-355.
21. Rut W, Dorfleutner A, Riewald M. Specificity of coagulation factor signaling. J Thromb Haemost. 2003;1:1495-1503.
22. Pendurthi UR, Alok D, Rao LVM. Binding of factor VIIa to tissue factor induces alterations in gene expression in human fibroblast cells: upregulation of poly(A) polymerase. Proc Natl Acad Sci U S A. 1997;94:12598-12603.
23. Pendurthi UR, Allen KE, Ezban M, Rao LVM. Factor VIIa and thromhin induce the expression of Cyr61 and connective tissue growth factor, extracellular matrix signaling proteins but could act as possible downstream mediators in factor VII tissue factor-induced signal transduction. J Biol Chem. 2000;275:14632-14641.
24. Camerer E, Rottingen J-A, Giernes E, et al. Coagulation factors VIIa and Xa induce cell signaling leading to up-regulation of the egr-1 gene. J Biol Chem. 1999;274:32225-32233.
25. Camerer E, Gjernes E, Wiiger M, Pringle S, Prydz H. Binding of tactor VIIa to tissue tactor on keratinocytes induces gene expression. J Biol Chem. 2000;275:6580-6585.
26. Wang X, Gjernes E, Prydz H. Factor VIIa induces tissue factor-dependent up-regulation of interleukin-8 in a human keratinocyte line. J Biol Chem. 2002;277:23620-23626.
27. Taniguchi T, Kakkar AK, Tuddenham EGD, Williamson RCN, Lemoine NRL. Enhanced expression of urokinase receptor induced through the tissue factor-factor VIIa pathway in human pancreatic cancer. Cancer Res. 1998;58:4461-4467.
28. De Larco JE, Wuertz BRK, Rosner KA, et al. A potential role for interleukin-8 in the metastatic phenotype of breast carcinoma cells. Am J Pathol. 2001;158:639-646.
29. Li A, Varney M, Singh RK. Expression of interleukin 8 and its receptors in human colon carcinoma cells with different metastatic potentials. Clin Cancer Res. 2001;7:3298-3304.
30. Singh RK, Varney M. IL-8 expression in malignant melanoma: implications in growth and metastasis. Histol Histopathol. 2000;15:843-849.
31. Bar-Eli M. Role of interleukin-8 in tumor growth and metastasis of human melanoma. Pathobiology. 1999;67:12-18.
32. Belperio JA, Keane MP, Arenberg DA, et al. CXC chemokines in angiogenesis. J Leukoc Biol. 2000;68:1-8.
33. Brew R, Erikson JS, West DC, et al. Interleukin-8 as an autocrine growth factor for human colon carcinoma cells in vitro. Cytokine. 2000;12:78-85.
34. Lang K, Niggeman B, Zanker K, Entschladen F. Signal processing of migrating T24 human bladder carcinoma cells: role of the autocrine interleukin-8. Int J Cancer. 2002;99:673-680.
35. Reiland J, Furcht LT, McCarthy JB. CSX-chemokines stimulate invasion and chemotaxis in prostate carcinoma cell through the CXCR2 receptor. Prostate. 1999;41:78-88.
36. Kuwada Y, Sasaki T, Morinaka K, et al. Potential involvement of IL-8 and its receptors in the invasiveness of pancreatic cancer cells. Int J Oncol. 2003;22:765-771.
37. Youngs SJ, Ali SA, Taub DD, Rees RC. Chemokines induce migrational responses in human breast carcinoma cell lines. Int J Cancer. 1997;71:257-266.
38. Li A, Dubey S, Varney ML, Dave BJ, Singh RK. IL-8 directly enhanced endothelial cell survival. proliferation, and matrix metalloproteinases production and regulated angiogenesis. J Immunol. 2003;170:3369-3376.
39. Rao LVM. Characterization of anti-tissue factor antibody and its use in immunoaffinity purification of human tissue factor. Thromb Res. 1988;51:373-384.
40. Fleck RA, Rao LVM, Rapaport SI, Varki N. Localization of human tissue factor antigen by immunostaining with monospecific, polyclonal anti-human tissue factor antibody. Thromb Res. 1990;59:421-437.
41. Thim L, Bioern S, Christensen M, et al. Amino acid sequence and posttranslational modifications of human factor VIIa from plasma and transfected baby hamster kidney cells. Biochemistry. 1988;27:7786-7793.
42. Sorensen BB, Persson E, Freskgard P-O, et al. Incorporation of an active site inhibitor in factor VIIa alters the affinity for tissue factor. J Biol Chem. 1997;272:11863-11868.
43. Rao LVM, Bajaj SP. Purification of human factor VII utilizing O-(Diethylaminoethyl)-Sephadex and Sulfopropyl-Sephadex chromatography. Anal Biochem. 1984;136:357-361.
44. Pendurthi UR, Okino ST, Tukey RH. Accumulation of the nuclear dioxin (Ah) receptor and transcriptional activation of the mouse Cyp 1a-1 and Cyp 1a-2 genes. Arch Biochem Biophys. 1993;306:65-69.
45. Zhou J-N, Ljungdahl S, Shoshan MC, Swedendorg J, Linder S. Activation of tissue factor gene expression in breast carcinoma cells by stimulation of the RAF-ERK signaling pathway. Mol Carcinog. 1998;21:234-243.
46. Wang JI, Deng X, Gong W, Su S. Chemokines and their role in tumor growth and metastasis. J Immunol Methods. 1998;220:1-17.
47. Sorensen BB, Rao LVM. Interaction of activated factor VIIa and active site-inhibited factor VIIa with tissue factor. Blood Coag Fibrinol. 1998;9(suppl 1):S67-S71.
48. + signals in J82 cells, transfected COS-1 cells, Madin-Darby canine kidney cells and in human endothelial cells induced to synthesize tissue factor. J Biol Chem. 1995;270:4650-4660.
49. Sorensen BB, Freskgard P-O, Nielsen LS, et al. Factor VIIa-induced p44/ 42 mitogen-activated kinase activation requires the proteolytic activity of factor VIIa and is independent of the tissue factor cytoplasmic domain. J Biol Chem. 1999;274:21349-21354.
50. Petersen LC, Thastrup O, Hagel G, et al. Exclusion of known protease activated receptors in factor VIIa-induced signal transduction. Thromb Haemost. 2000;83:571-576.
51. Camerer E, Huang W, Coughlin SR. Tissue factor- and factor X-dependent activation of protease-activated receptor-2 by factor VIIa. Proc Natl Acad Sci U S A. 2000;97:5255-5260.
52. Pendurthi U, Sorensen BB, Petersen LC, et al. Factor VIIa induced signaling in fibroblasts [abstract]. Blood. 2000;96:635.
53. Riewald M, Ruf W. Mechanistic coupling of protease signaling and initiation of coagulation by tissue factor. Proc Natl Acad Sci U S A. 2001;98:7742-7747.
54. Fair DS, MacDonald MJ. Cooperative interaction between factor VII and cell surface-expressed tissue factor. J Biol Chem. 1987;262:11692-11698.
55. Le DT, Rapaport SI, Rao LVM. Relations between factor VIIa binding and expression of factor VIIa/tissue factor catalytic activity on cell surfaces. J Biol Chem. 1992;267:15447-15454.
56. Nakagaki T, Foster DC, Berkner KL, Kisiel W. Initiation of the extrinsic pathway of blood coagulation: evidence for the tissue factor dependent autoactivation of human coagulation factor VII. Biochemistry. 1991;30:10819-10824.
57. Rao LVM, Williams T, Rapaport SI. Studies of the activation of factor VII bound to tissue factor. Blood. 1996;87:3738-3748.
58. Hou L, Kapas S, Crutchley AT, et al. Immunolocalization of protease-activated receptor-2 in skin: receptor activation stimulates interluekin-8 secretion by keratinocytes in vitro. Immunology, 1998;94:356-362.
59. 2 release from human respiratory epithelial cells. J Immunol. 2002;168:3577-3585.
60. Shpacovitch VM, Brzoska T, Buddenkotte J, et al. Agonists of protease-activated receptor-2 induce cytokine release and activation of nuclear transcription factor κB in human dermal microvascular endothelial cells. J Invest Dermatol. 2002;118:380-385.
61. Macfarlane SR, Seatter MJ, Kanke T, Hunter GD, Plevin R. Proteinase-activated receptors. Pharmacol Rev. 2001:53:245-282.
62. Riewald M, Petrovan RJ, Donner A, Mueller BM, Ruf W. Activation of endothelial cell protease activated receptor 1 by protein C pathway. Science. 2002;296:1880-1882.
63. Pendurthi UR, Ngyuen M, Andrade-Gordon P, Petersen LC, Rao LVM. Plasmin induces Cyr61 gene expression in fibroblasts via protease activated receptor-1 and p44/42 mitogen-activated protein kinase-dependent signaling pathway. Arterioscler Thromb Vasc Biol. 2002;22:1421-1426.
64. Riewald M, Kravchenko VV, Petrovan R, et al. Gene induction by coagulation factor Xa is mediated by activation of PAR-1. Blood. 2001;97:3109-3116.
65. Kamath L, Meydani A, Foss F, Kuliopulos A. Signaling from protease-activated receptor-1 inhibits migration and invasion of breast cancer cells. Cancer Res. 2001;61:5933-5940.
66. Bono F, Schaeffer P, Herault J-P, et al. Factor Xa activates endothelial cells by a receptor cascade between EPR-1 and PAR-2. Arterioscler Thromb Vasc Biol. 2000;20:e107-e112.
67. Camerer E, Kataoka H, Kahn M, Lease K, Coughlin SR. Genetic evidence that protease-activated receptors mediate factor Xa signaling in endothelial cells. J Biol Chem. 2002;277:16081-16087.
68. Inoue K, Slaton JW, Eve BY, et al. Interleukin 8 expression regulates tumorigenecity and metastases in androgen-dependent prostate cancer. Clin Cancer Res. 2000;6:2104-2119.
69. Satyamoorthy K, Li G, Vaidya B, Kalabis J, Herlyn M. Insulin-like growth factor-I induced migration of melanoma cells is mediated by interleukin-8 induction. Cell Growth Differ. 2002;13:87-93.
70. Marutsuka K, Hatakeyama K, Sato Y, et al. Protease-activated receptor-2 (PAR2) mediates vascular smooth muscle cell migration induced by tissue factor/factor VIIA complex. Thromb Res. 2002;107:271-276.
71. Siegbahn A, Johnell M, Rorsman C, et al. Binding of factor VIIA to tissue factor on human fibroblasts leads to activation of phospholipase C and enhanced PDGF-BB-stimulated chemotaxis. Blood. 2000;96:3452-3458.
72. Sato Y, Asada Y, Marutsuka K, Hatakeyama K. Tissue factor induces migration of cultured aortic smooth muscle cells. Thromb Haemost. 1996;75:389-392.
73. 1 in stimulating human endothelial cell exocytosis and permeability: the role of Rho-GTPases. Circ Res. 2003;92:272-278.
74. Vouret-Cravian V, Grail D, Van Obberghen-Schilling E. Modulation of Rho GTPase activity in endothetial cells by selective proteinase-activated receptor (PAR) agonists. J Thromb Haemost. 2003;1:1103-1111.
75. 5 integrin. J Biol Chem. 2001;276:10952-10956.
76. Sorensen BB, Rao LVM, Tornehave D, Gammeltoft S, Petersen LC. Antiapoptotic effect of coagulation factor VIIa. Blood. 2003;102:1708-1715.
77. Cirillo P, Guarino A, Ragni M, et al. Activated coagulation factor VII promotes smooth muscle cell proliferation in vitro [abstract]. Circulation. 1999;100(suppl 1):1-699.