Alternatively spliced human tissue factor promotes tumor growth and angiogenesis in a pancreatic cancer tumor model

Thrombosis Research

Volumn 120, Issue SUPPL. 2, 2007, Pages

  Hobbs, Jennifer E ^a   Zakarija, Anaadriana ^a   Cundiff, Deborah L ^a   Doll, Jennifer A ^a   Hymen, Emily ^a   Cornwell, Mona ^a   Crawford, Susan E ^a   Liu, Na ^b   Signaevsky, Maxim ^b   Soff, Gerald A ^a,b  

^a NORTHWESTERN UNIVERSITY   (United States)

^b STATE UNIVERSITY OF NEW YORK   (United States)

Author keywords

Alternatively spliced human tissue factor; Cancer; Coagulation; Thrombosis; Tissue factor

Indexed keywords

THROMBOPLASTIN;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CANCER GROWTH; CELL PROLIFERATION; COMPARATIVE STUDY; CONTROLLED STUDY; EXPRESSION VECTOR; FIBROBLAST; HUMAN; HUMAN CELL; MICROVASCULATURE; MITOSIS; MOUSE; NONHUMAN; NUDE MOUSE; PANCREAS CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; TUMOR GROWTH;

ALTERNATIVE SPLICING; ANIMALS; BLOOD COAGULATION; CELL DIVISION; CELL LINE, TUMOR; CLONE CELLS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; NEOVASCULARIZATION, PATHOLOGIC; PANCREATIC NEOPLASMS; THROMBOPLASTIN; THROMBOSIS; TRANSFECTION;

EID: 36049042581     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0049-3848(07)70126-3     Document Type: Article

References (54)

1. Trousseau A., Bazire P., and Cormack J. Lectures on clinical medicine (1867), R. Hardwicke, London
2. Broze Jr. G. The tissue factor pathway of coagulation. In: Loscalzo J., and Schafer A. (Eds). Thrombosis and Hemorrhage (2003), Lippincott, Williams, & Wilkins, Philadelphia 62-80
3. Morrissey J. Tissue factor: in at the start. And the finish?. J Thromb Haemost (2003) 878-880
4. Morrissey J. Tissue factor: a key molecule in hemostatic and nonhemostatic systems. Int J Hematol 79 (2004) 103-108
5. Schenone M., Furie B., and Furie B. The blood coagulation cascade. Curr Opin Hematol 11 (2004) 272-277
6. Donati M., and Lorenzet R. The role of blood clotting in tumor metastasis: A case for tissue factor. In: Lugassy G., Falanga A., Kakkar A., and Rickles F. (Eds). Thrombosis and Cancer (2004), Martin Dunitz, an imprint of the Taylor & Francis Group, London 47-58
7. Falanga A., and Donati M. Pathogenesis of thrombosis in patients with malignancy. Int J Hematol 73 (2001) 137-144
8. Falanga A., Marchetti M., and Vignoli A. Pathogenesis of thrombosis in cancer. In: Lugassy G., Falanga A., Kakkar A., and Rickles F. (Eds). Thrombosis and Cancer (2004), Martin Duntz, an imprint of the Taylor & Francis Group, London 11-30
9. Khorana A. Malignancy, thrombosis and Trousseau: the case for an eponym. J Thromb Haemost 1 (2003) 2463-2465
10. Khorana A., and Fine R. Pancreatic cancer and thromboembolic disease. Lancet Oncol 5 (2004) 655-663
11. Rickles F., and Levine M. Epidemiology of thrombosis in cancer. Acta Haematol 106 (2001) 6-12
12. Rickles F., Patierno S., and Fernandez P. Tissue factor, thrombin, and cancer. Chest 124 (2003) 58S-68S
13. Rickles F., Shoji M., and Abe K. The role of the hemostatic system in tumor growth, metastasis, and angiogenesis: tissue factor is a bifunctional molecule capable of inducing both fibrin deposition and angiogenesis in cancer. Int J Hematol 73 (2001) 145-150
14. Bithell T. Blood Coagulation. In: Lee G., Bithell T., Foerster J., Athens J., and Lukens J. (Eds). Wintrobe's Clinical Hematology (1993), Lea & Febiger, Philadelphia 566-615
15. Rickles F., and Falanga A. Molecular basis for the relationship between thrombosis and cancer. Thromb Res 102 (2001) V215-V224
16. Mueller B., and Ruf W. Requirement for binding of catalytically active factor VIIa in tissue factor-dependent experimental metastasis. J Clin Invest 101 (1998) 1372-1378
17. Ott I., Fischer E., Miyagi Y., Mueller B., and Ruf W. A role for tissue factor in cell adhesion and migration mediated by interaction with actin-binding protein 280. J Cell Biol 140 (1998) 1241-1253
18. Ruf W., and Mueller B. Tissue factor signaling. Thromb Haemost 82 (1999) 175-182
19. Kakkar A., Chinswangwatanakul V., Lemoine N., Tebbutt S., and Williamson R. Role of tissue factor expression on tumour cell invasion and growth of experimental pancreatic adenocarcinoma. Br J Surg 86 (1999) 890-894
20. Bogdanov V., Balasubramanian V., Hathcock J., Vele O., Lieb M., and Nemerson Y. Alternatively spliced human tissue factor: a circulating, soluble, thrombogenic protein. Nat Med 9 (2003) 458-462
21. Censarek P., Bobbe A., Grandoch M., Schror K., and Weber A. Alternatively spliced human tissue factor (asHTF) is not procoagulant. Thromb Haemost 97 (2007) 11-14
22. Gately S., Twardowski P., Stack M., Cundiff D., Grella D., Castellino F., et al. The mechanism of cancer-mediated conversion of plasminogen to the angiogenesis inhibitor angiostatin. Proc Natl Acad Sci USA 94 (1997) 10868-10872
23. Larsson P., Roos G., Stenling R., Wilson G., and Ljungberg B. Cell proliferation in renal cell carcinoma-a comparative study of cell kinetic methods. Urol Res 24 (1996) 291-295
24. Diamant M., Tushuizen M., Sturk A., and Nieuwland R. Cellular microparticles: new players in the field of vascular disease?. Eur J Clin Invest 34 (2004) 392-401
25. Mallat Z., Hugel B., Ohan J., Leseche G., Freyssinet J., and Tedgui A. Shed membrane microparticles with procoagulant potential in human atherosclerotic plaques: a role for apoptosis in plaque thrombogenicity. Circulation 99 (1999) 348-353
26. Yu J., May L., Klement P., Weitz J., and Rak J. Oncogenes as regulators of tissue factor expression in cancer: implications for tumor angiogenesis and anti-cancer therapy. Semin Thromb Hemost 30 (2004) 21-30
27. Levitan N., Dowlati A., Remick S., Tahsildar H., Sivinski L., Beyth R., et al. Rates of initial and recurrent thromboembolic disease among patients with malignancy versus those without malignancy. Risk analysis using Medicare claims data. Medicine (Baltimore) 78 (1999) 285-291
28. Sorensen H., Mellemkjaer L., Olsen J., and Baron J. Prognosis of cancers associated with venous thromboembolism. N Engl J Med 343 (2000) 1846-1850
29. Ruf W., and Mueller B. Tissue factor in cancer angiogenesis and metastasis. Curr Opin Hematol 3 (1996) 379-384
30. Guan M., Jin J., Su B., Liu W., and Lu Y. Tissue factor expression and angiogenesis in human glioma. Clin Biochem 35 (2002) 321-325
31. Hamada K., Kuratsu J., Saitoh Y., Takeshima H., Nishi T., and Ushio Y. Expression of tissue factor correlates with grade of malignancy in human glioma. Cancer 77 (1996) 1877-1883
32. Hamada K., Kuratsu J., Saitoh Y., Takeshima H., Nishi T., and Ushio Y. Expression of tissue factor in glioma. Noshuyo Byori 13 (1996) 115-118
33. Kakkar A., Lemoine N., Scully M., Tebbutt S., and Williamson R. Tissue factor expression correlates with histological grade in human pancreatic cancer. Br J Surg 82 (1995) 1101-1104
34. Seto S., Onodera H., Kaido T., Yoshikawa A., Ishigami S., Arii S., et al. Tissue factor expression in human colorectal carcinoma: correlation with hepatic metastasis and impact on prognosis. Cancer 88 (2000) 295-301
35. Costantini V., and Zacharski L. Fibrin and cancer. Thromb Haemost 69 (1993) 406-414
36. Fernandez P., Patierno S., and Rickles F. Tissue factor and fibrin in tumor angiogenesis. Semin Thromb Hemost 30 (2004) 31-44
37. Fernandez P., Patierno S., and Rickles F. Tumor angiogenesis and blood coagulation. In: Lugassy G., Falanga A., Kakkar A., and Rickles F. (Eds). Thrombosis and Cancer (2004), Martin Dunitz, an imprint of the Taylor & Francis Group, London 69-98
38. Ruf W. Tissue factor-dependent signaling in tumor biology. Pathophysiol Haemost Thromb 33 Suppl 1 (2003) 28-30
39. Ruf W., Dorfleutner A., and Riewald M. Specificity of coagulation factor signaling. J Thromb Haemost 1 (2003) 1495-1503
40. Sampson M., and Kakkar A. Coagulation proteases and human cancer. Biochem Soc Trans 30 (2002) 201-207
41. Versteeg H., Hoedemaeker I., Diks S., Stam J., Spaargaren M., van Bergen en Henegouwen P., et al. Factor VIIa/tissue factor-induced signaling via activation of Src-like kinases, phosphatidyl 3-kinase, and Rac. J Biol Chem 275 (2000) 28750-28756
42. Nierodzik M., and Karpatkin S. Thrombin induces tumor growth, metastasis, and angiogenesis: Evidence for a thrombin-regulated dormant tumor phenotype. Cancer Cell 10 (2006) 355-362
43. Versteeg H., and Ruf W. Emerging insights in tissue factor-dependent signaling events. Semin Thromb Hemost 32 (2006) 24-32
44. Lee A., Levine M., Baker R., Bowden C., Kakkar A., Prins M., et al. Low-molecular-weight heparin versus a coumarin for the prevention of recurrent venous thromboembolism in patients with cancer. N Engl J Med 349 (2003) 146-153
45. Kakkar A., Levine M., Kadziola Z., Lemoine N., Low V., Patel H., et al. Low molecular weight heparin, therapy with dalteparin, and survival in advanced cancer: the fragmin advanced malignancy outcome study (FAMOUS). J Clin Oncol 22 (2004) 1944-1948
46. Klerk C., Smorenburg S., Otten H., Lensing A., Prins M., Piovella F., et al. The effect of low molecular weight heparin on survival in patients with advanced malignancy. J Clin Oncol 23 (2005) 2130-2135
47. Chand H., Ness S., and Kisiel W. Identification of a novel human tissue factor splice variant that is upregulated in tumor cells. Int J Cancer 118 (2006) 1713-1720
48. Haas S., Jesnowski R., Steiner M., Hummel F., Ringel J., Burstein C., et al. Expression of tissue factor in pancreatic adenocarcinoma is associated with activation of coagulation. World J Gastroenterol 12 (2006) 4843-4849
49. Hu L., Lee M., Campbell W., Perez-Soler R., and Karpatkin S. Role of endogenous thrombin in tumor implantation, seeding, and spontaneous metastasis. Blood 104 (2004) 2746-2751
50. Karpatkin S. Role of thrombin in tumor angiogenesis, implantation, and metastasis. Pathophysiol Haemost Thromb 33 Suppl 1 (2003) 54-55
51. Nierodzik M., Kajumo F., and Karpatkin S. Effect of thrombin treatment of tumor cells on adhesion of tumor cells to platelets in vitro and tumor metastasis in vivo. Cancer Res 52 (1992) 3267-3272
52. Folkman J. Angiogenesis. Annu Rev Med 57 (2006) 1-18
53. Folkman J. Angiogenesis: an organizing principle for drug discovery?. Nat Rev Drug Discov 6 (2007) 273-286
54. Kerbel R., and Folkman J. Clinical translation of angiogenesis inhibitors. Nat Rev Cancer 2 (2002) 727-739