Fatal embryonic bleeding events in mice lacking tissue factor, the cell-associated initiator of blood coagulation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 13, 1996, Pages 6258-6263

  Bugge, Thomas H ^a,b   Xiao, Qing ^a   Kombrinck, Keith W ^a   Flick, Matthew J ^a   Holmbäck, Kenn ^a   Danton, Mary Jo S ^a   Colbert, Melissa C ^a   Witte, David P ^a   Fujikawa, Kazuo ^c   Davie, Earl W ^c   Degen, Jay L ^a  

^a CINCINNATI CHILDREN S HOSPITAL RESEARCH FOUNDATION   (United States)

^b FINSEN LABORATORY   (Denmark)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Embryonic development; Gene targeting

Indexed keywords

THROMBOPLASTIN;

ANIMAL MODEL; ARTICLE; BLEEDING DISORDER; EMBRYO; EMBRYO MORTALITY; GENE DISRUPTION; GENE EXPRESSION; HETEROZYGOSITY; HISTOPATHOLOGY; HOMOZYGOSITY; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BASE SEQUENCE; BLOOD COAGULATION DISORDERS; DNA PRIMERS; FETAL DEATH; GENES, LETHAL; HEMORRHAGE; HETEROZYGOTE; HOMOZYGOTE; MICE; MOLECULAR SEQUENCE DATA; PHENOTYPE; THROMBOPLASTIN;

EID: 0029908545     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.13.6258     Document Type: Article

References (21)

1. Davie, E. W., Fujikawa, K. & Kisiel, W. (1991) Biochemistry 30, 10363-10370.
2. Triplett, D. A. (1984) Clin. Lab. Med. 4, 221-244.
3. Drake, T. A., Morrissey, J. H. & Edgington, T. S. (1989) Am. J. Pathol. 134, 1087-1097.
4. Mueller, B. M., Reisfeld, R. A., Edgington, T. S. & Ruf, T. (1992) Proc. Natl. Acad. Sci. USA 89, 11832-11836.
5. Bromberg, M. E., Konigsberg, W. H., Madison, J. F., Pawashe, A. & Garen. A. (1995) Proc. Natl. Acad. Sci. USA 92, 8205-8209.
6. Mackman, N. (1995) FASEB J. 9, 883-889.
7. Mackman, N., Imes, S., Maske, W. H., Taylor, B., Lusis, A. J. & Drake, T. A. (1992) Arterioscler. Thromb. 12, 474-483.
8. van der Lugt, N., Maandag, E. R., teRiele, H., Laird, P. W. & Berns, A. (1991) Gene 105, 263-267.
9. Mansour, S. L., Thomas, K. R. & Capecchi, M. R. (1988) Nature (London) 336, 348-352.
10. Bugge, T. H., Flick, M. J., Daugherty, C. C. & Degen, J. L. (1995) Genes Dev. 9, 794-807.
11. Suh, T. T., Holmbäck, K., Jensen, N. J., Daugherty, C. C., Small, K., Simon, D. I., Potter, S. S. & Degen, J. L. Genes Dev. 9, 2020-2033.
12. Dickson, M. C., Martin, J. S., Cousins, F. M., Kulkarni, A. B., Karlsson, S. & Akhurst, R. S. (1995) Development 121, 1845-1854.
13. Yang, J. T., Rayburn, H. & Hynes, R. O. (1993) Development 119, 1093-1105.
14. Shalaby, F., Rossant, J., Yamaguchi, T. P., Gertsenstein, M., Wu, X.-F., Breitman, M. L. & Schuh, A. C. (1995) Nature (London) 376, 62-66.
15. Fong, G.-H., Rossant, J., Gertsenstein, M. & Breitman, M. L. (1995) Nature (London) 376, 66-70.
16. Robb, L., Lyons, I., Li., R., Hartley, L., Köntgen, F., Harvey, R. P., Metcalf, D. & Begley, C. G. (1995) Proc. Natl. Acad. Sci. USA 92, 7075-7079.
17. Shivdasani, R. A., Mayer, E. L. & Orkin, S. H. (1995) Nature (London) 373, 432-434.
18. Warren, A. J., Colledge, W. H., Carlton, M. B. L., Evans, M. J., Smith, A. J. H. & Rabbits, T. H. (1994) Cell 78, 45-57.
19. Tsai, F.-Y., Keller, G., Kuo, F. C., Weiss, M., Chen, J., Rosenblatt, M., Alt, F. W. & Orkin, S. H. (1994) Nature (London) 371, 221-226.
20. Healy, A. M., Rayburn, H. B., Rosenberg, R. D. & Weiler, H. (1995) Proc. Natl. Acad. Sci. USA 92, 850-854.
21. Rosenberg, R. D. (1995) Thromb. Haemostasis 74, 52-57.