Ionizing radiation induces upregulation of cellular procoagulability and tissue factor expression in human peripheral blood mononuclear cells

Thrombosis Research

Volumn 120, Issue 6, 2007, Pages 857-864

  Goldin Lang, Petra ^a   Niebergall, Florian ^a   Antoniak, Silvio ^a   Szotowski, Bjoern ^a   Rosenthal, Peter ^a   Pels, Klaus ^a   Schultheiss, Heinz Peter ^a   Rauch, Ursula ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Ionizing radiation; Peripheral blood mononuclear cells; Procoagulability; Tissue factor

Indexed keywords

THROMBOPLASTIN;

ARTICLE; BLOOD CLOTTING; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; IONIZING RADIATION; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; THROMBOGENICITY; THROMBOSIS; UPREGULATION;

BLOOD COAGULATION; CELLS, CULTURED; HUMANS; LEUKOCYTES, MONONUCLEAR; PARTICLE SIZE; RADIATION, IONIZING; THROMBOPLASTIN; THROMBOSIS; TIME FACTORS; UP-REGULATION;

EID: 34548688681     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.thromres.2007.01.008     Document Type: Article

References (32)

1. Teirstein P.S., and Kuntz R.E. New frontiers in interventional cardiology: intravascular radiation to prevent restenosis. Circulation 104 21 (2001) 2620-2626
2. Saleem M.A., Aronow W.S., Ravipati G., Moorthy C.R., Singh S., Agarwal N., et al. Intracoronary brachytherapy for treatment of in-stent restenosis. Cardiol Rev 13 3 (2005) 139-141
3. Waksman R. Vascular brachytherapy: applications in the era of drug-eluting stents. Rev Cardiovasc Med 3 Suppl 5 (2002) S23-S30
4. Waksman R. Late thrombosis after radiation. Sitting on a time bomb. Circulation 100 8 (1999) 780-782
5. Finkelstein A., Hausleiter J., Doherty T., Takizawa K., Bergman J., Liu M., et al. Intracoronary beta-irradiation enhances balloon-injury-induced tissue factor expression in the porcine injury model. Int J Cardiovasc Interv 6 1 (2004) 20-27
6. Van der Meeren A., Vandamme M., Squiban C., Gaugler M.H., and Mouthon M.A. Inflammatory reaction and changes in expression of coagulation proteins on lung endothelial cells after total-body irradiation in mice. Radiat Res 160 6 (2003) 637-646
7. Giesen P.L., Rauch U., Bohrmann B., Kling D., Roque M., Fallon J.T., et al. Blood-borne tissue factor: another view of thrombosis. Proc Natl Acad Sci U S A 96 5 (1999) 2311-2315
8. Rauch U., and Nemerson Y. Circulating tissue factor and thrombosis. Curr Opin Hematol 7 5 (2000) 273-277
9. Rauch U., and Nemerson Y. Tissue factor, the blood, and the arterial wall. Trends Cardiovasc Med 10 4 (2000) 139-143
10. Rauch U., Bonderman D., Bohrmann B., Badimon J.J., Himber J., Riederer M.A., et al. Transfer of tissue factor from leukocytes to platelets is mediated by CD15 and tissue factor. Blood 96 1 (2000) 170-175
11. Rauch U., Osende J.I., Fuster V., Badimon J.J., Fayad Z., and Chesebro J.H. Thrombus formation on atherosclerotic plaques: pathogenesis and clinical consequences. Ann Intern Med 134 3 (2001) 224-238
12. Niemetz J., and Fani K. Thrombogenic activity of leukocytes. Blood 42 1 (1973) 47-59
13. Garg S.K., and Niemetz J. Tissue factor activity of normal and leukemic cells. Blood 42 5 (1973) 729-735
14. Satta N., Toti F., Feugeas O., Bohbot A., Chary-Prigent J., Eschwege V., et al. Monocyte vesiculation is a possible mechanism for dissemination of membrane-associated procoagulant activities and adhesion molecules after stimulation by lipopolysaccharide. J Immunol 153 7 (1994) 3245-3255
15. Mallat Z., Benamer H., Hugel B., Benessiano J., Steg P.G., Freyssinet J.M., et al. Elevated levels of shed membrane microparticles with procoagulant potential in the peripheral circulating blood of patients with acute coronary syndromes. Circulation 101 8 (2000) 841-843
16. Nieuwland R., Berckmans R.J., McGregor S., Boing A.N., Romijn F.P., Westendorp R.G., et al. Cellular origin and procoagulant properties of microparticles in meningococcal sepsis. Blood 95 3 (2000) 930-935
17. Osterud B., and Bjorklid E. The tissue factor pathway in disseminated intravascular coagulation. Semin Thromb Hemost 27 6 (2001) 605-617
18. Bogdanov V.Y., Balasubramanian V., Hathcock J., Vele O., Lieb M., and Nemerson Y. Alternatively spliced human tissue factor: a circulating, soluble, thrombogenic protein. Nat Med 9 4 (2003) 458-462
19. Szotowski B., Antoniak S., Poller W., Schultheiss H.P., and Rauch U. Procoagulant soluble tissue factor is released from endothelial cells in response to inflammatory cytokines. Circ Res 96 12 (2005) 1233-1239
20. Verheij M., Dewit L.G., and van Mourik J.A. The effect of ionizing radiation on endothelial tissue factor activity and its cellular localization. Thromb Haemost 73 5 (1995) 894-895
21. Wang J., Zheng H., Ou X., Albertson C.M., Fink L.M., Herbert J.M., et al. Hirudin ameliorates intestinal radiation toxicity in the rat: support for thrombin inhibition as strategy to minimize side-effects after radiation therapy and as countermeasure against radiation exposure. J Thromb Haemost 2 11 (2004) 2027-2035
22. Rivers R.P., Hathaway W.E., and Weston W.L. The endotoxin-induced coagulant activity of human monocytes. Br J Haematol 30 3 (1975) 311-316
23. Niemetz J., and Fani K. Role of leukocytes in blood coagulation and the generalized Shwartzman reaction. Nat New Biol 232 34 (1971) 247-248
24. Dainiak N., Waselenko J.K., Armitage J.O., MacVittie T.J., and Farese A.M. The hematologist and radiation casualties. Hematol Am Soc Hematol Educ Program (2003) 473-496
25. Freyssinet J.M. Cellular microparticles: what are they bad or good for?. J Thromb Haemost 1 7 (2003) 1655-1662
26. Henriksson C.E., Klingenberg O., Hellum M., Landsverk K.S., Joo G.B., Westvik A.B., et al. Calcium ionophore-induced de-encryption of tissue factor in monocytes is associated with extensive cell death. Thromb Res (2006)
27. Eilertsen K.E., and Osterud B. Tissue factor: (patho)physiology and cellular biology. Blood Coagul Fibrinolysis 15 7 (2004) 521-538
28. Aras O., Shet A., Bach R.R., Hysjulien J.L., Slungaard A., Hebbel R.P., et al. Induction of microparticle- and cell-associated intravascular tissue factor in human endotoxemia. Blood 103 12 (2004) 4545-4553
29. Mackman N. Role of tissue factor in hemostasis and thrombosis. Blood Cells Mol Diseases 36 2 (2006) 104-107
30. Llorente-Cortes V., Otero-Vinas M., Camino-Lopez S., Llampayas O., and Badimon L. Aggregated low-density lipoprotein uptake induces membrane tissue factor procoagulant activity and microparticle release in human vascular smooth muscle cells. Circulation 110 4 (2004) 452-459
31. Szotowski B., Antoniak S., Goldin-Lang P., Tran Q.V., Pels K., Rosenthal P., et al. Antioxidative treatment inhibits the release of thrombogenic tissue factor from irradiation- and cytokine-induced endothelial cells. Cardiovasc Res 73 4 (2007) 806-812 (Mar 1)
32. Szotowski B., Antoniak S., and Rauch U. Alternatively spliced tissue factor: a previously unknown piece in the puzzle of hemostasis. Trends Cardiovasc Med 16 5 (2006) 177-182