The serum- and glucocorticoid-inducible kinase Sgk-1 is involved in pulmonary vascular remodeling: Role in redox-sensitive regulation of tissue factor by thrombin

Circulation Research

Volumn 98, Issue 6, 2006, Pages 828-836

  Belaiba, Rachida S ^a   Djordjevic, Talija ^a   Bonello, Steve ^a   Artunc, Ferruh ^b   Lang, Florian ^b   Hess, John ^a   Görlach, Agnes ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

Coagulant activity; NADPH oxidase; Nuclear factor B; Pulmonary artery smooth muscle cells; Pulmonary vascular remodeling; Sgk 1; Thrombin; Tissue factor

Indexed keywords

ANTIOXIDANT; DEXAMETHASONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; RAC PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SERUM AND GLUCOCORTICOID REGULATED KINASE 1; THROMBIN; THROMBOPLASTIN; 3 PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE; 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE; IMMEDIATE EARLY PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN SERINE THREONINE KINASE; REACTIVE OXYGEN METABOLITE; SGK PROTEIN;

ANIMAL EXPERIMENT; ARTERY MUSCLE; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; FIBROBLAST; HEART VENTRICLE REMODELING; HUMAN; HUMAN CELL; LUNG BLOOD FLOW; LUNG BLOOD VESSEL; MOUSE; NONHUMAN; OSMOREGULATION; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PULMONARY HYPERTENSION; SMOOTH MUSCLE FIBER; SURVIVAL RATE; TRANSCRIPTION REGULATION; ANIMAL; CELL CULTURE; GENETICS; MOUSE MUTANT; PATHOLOGY; PHYSIOLOGY; PULMONARY ARTERY; VASCULAR SMOOTH MUSCLE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CELLS, CULTURED; HUMANS; HYPERTENSION, PULMONARY; IMMEDIATE-EARLY PROTEINS; MICE; MICE, KNOCKOUT; MUSCLE, SMOOTH, VASCULAR; NADPH OXIDASE; NF-KAPPA B; OXIDATION-REDUCTION; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; PULMONARY ARTERY; REACTIVE OXYGEN SPECIES; THROMBIN; THROMBOPLASTIN;

EID: 33645730645     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000210539.54861.27     Document Type: Article

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