Impaired hemostasis and protection against thrombosis in protease-activated receptor 4-deficient mice is due to lack of thrombin signaling in platelets

Journal of Thrombosis and Haemostasis

Volumn 2, Issue 8, 2004, Pages 1429-1435

  Hamilton, J R ^a   Cornelissen, I ^a   Coughlin, S R ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Hemostasis; Knockout mouse; Platelets; Protease activated receptor; Thrombosis

Indexed keywords

PROTEINASE ACTIVATED RECEPTOR 4; THROMBIN; THROMBOPLASTIN; TRANSCRIPTION FACTOR NF E2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLEEDING TIME; BONE MARROW CELL; CELL TYPE; CONTROLLED STUDY; FEMALE; HEMATOPOIETIC CELL; HEMOSTASIS; IRRADIATION; LETHALITY; LUNG EMBOLISM; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTECTION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; THROMBOCYTE; THROMBOCYTOPENIA; THROMBOSIS;

ANIMALS; BLOOD PLATELETS; BONE MARROW CELLS; BONE MARROW TRANSPLANTATION; CELL SEPARATION; DNA-BINDING PROTEINS; ERYTHROID-SPECIFIC DNA-BINDING FACTORS; FEMALE; FLOW CYTOMETRY; GENOTYPE; HEMOSTASIS; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; NF-E2 TRANSCRIPTION FACTOR; NF-E2 TRANSCRIPTION FACTOR, P45 SUBUNIT; PHENOTYPE; PULMONARY EMBOLISM; RECEPTORS, THROMBIN; SIGNAL TRANSDUCTION; THROMBIN; THROMBOPLASTIN; THROMBOSIS; TIME FACTORS; TRANSCRIPTION FACTORS;

EID: 13244273430     PISSN: 15387933     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2004.00783.x     Document Type: Article

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