-
2
-
-
0032458322
-
Mechanisms of hypercoagulation in malignancy and during chemotherapy
-
Falanga A. Mechanisms of hypercoagulation in malignancy and during chemotherapy. Haemostasis 1998;28:50-60.
-
(1998)
Haemostasis
, vol.28
, pp. 50-60
-
-
Falanga, A.1
-
5
-
-
0037087585
-
Dose-finding and pharmacokinetic study of cisplatin, gemcitabine, and SUS416 in patients with solid tumors
-
Kuenen BC, Rosen L, Smit EF, et al. Dose-finding and pharmacokinetic study of cisplatin, gemcitabine, and SUS416 in patients with solid tumors. J Clin Oncol 2002;20:1657-67.
-
(2002)
J Clin Oncol
, vol.20
, pp. 1657-1667
-
-
Kuenen, B.C.1
Rosen, L.2
Smit, E.F.3
-
6
-
-
0037087653
-
Unexpected serious toxicity with chemotherapy and antiangiogenic combinations: Time to take stock!
-
Marx GM, Steer CB, Harper P, Pavlakis N, Rixe O, Khayat D. Unexpected serious toxicity with chemotherapy and antiangiogenic combinations: time to take stock! J Clin Oncol 2002;20:1446-8.
-
(2002)
J Clin Oncol
, vol.20
, pp. 1446-1448
-
-
Marx, G.M.1
Steer, C.B.2
Harper, P.3
Pavlakis, N.4
Rixe, O.5
Khayat, D.6
-
7
-
-
0036718003
-
Results of a phase I dose-escalating study of the antiangiogenic agent, SU5416, in patients with advanced malignancies
-
Stopeck A, Sheldon M, Vahedian M, Cropp G, Gosalia R, Hannah A. Results of a phase I dose-escalating study of the antiangiogenic agent, SU5416, in patients with advanced malignancies. Clin Cancer Res 2002;8:2798-805.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 2798-2805
-
-
Stopeck, A.1
Sheldon, M.2
Vahedian, M.3
Cropp, G.4
Gosalia, R.5
Hannah, A.6
-
8
-
-
0038327794
-
Efficacy and toxicity of the angiogenesis inhibitor SU5416 as a single agent in patients with advanced renal cell carcinoma, melanoma, and soft tissue sarcoma
-
Kuenen BC, Tabernero J, Baselga J, et al. Efficacy and toxicity of the angiogenesis inhibitor SU5416 as a single agent in patients with advanced renal cell carcinoma, melanoma, and soft tissue sarcoma. Clin Cancer Res 2003;9:1648-55.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 1648-1655
-
-
Kuenen, B.C.1
Tabernero, J.2
Baselga, J.3
-
9
-
-
0037103101
-
A pilot study of thalidomide in patients with progressive metastatic renal cell carcinoma
-
Daliani DD, Papandreou CN, Thall PF, et al. A pilot study of thalidomide in patients with progressive metastatic renal cell carcinoma. Cancer 2002;95: 758-65.
-
(2002)
Cancer
, vol.95
, pp. 758-765
-
-
Daliani, D.D.1
Papandreou, C.N.2
Thall, P.F.3
-
10
-
-
4544332965
-
Deep vein thrombosis in patients with multiple myeloma treated with thalidomide and chemotherapy: Effects of prophylactic and therapeutic anticoagulation
-
Zangari M, Barlogie B, Anaissie E, et al. Deep vein thrombosis in patients with multiple myeloma treated with thalidomide and chemotherapy: effects of prophylactic and therapeutic anticoagulation. Br J Haematol 2004;126:715-21.
-
(2004)
Br J Haematol
, vol.126
, pp. 715-721
-
-
Zangari, M.1
Barlogie, B.2
Anaissie, E.3
-
11
-
-
0037530506
-
Potential role of platelets in endothelial damage observed during treatment with cisplatin, gemcitabine, and the angiogenesis inhibitor SU5416
-
Kuenen BC, Levi M, Meijers JC, et al. Potential role of platelets in endothelial damage observed during treatment with cisplatin, gemcitabine, and the angiogenesis inhibitor SU5416. J Clin Oncol 2003;21:2192-8.
-
(2003)
J Clin Oncol
, vol.21
, pp. 2192-2198
-
-
Kuenen, B.C.1
Levi, M.2
Meijers, J.C.3
-
12
-
-
0034917278
-
Tissue factor: An enzyme cofactor and a true receptor
-
Morrissey JH. Tissue factor: an enzyme cofactor and a true receptor. Thromb Haemost 2001;86:66-74.
-
(2001)
Thromb Haemost
, vol.86
, pp. 66-74
-
-
Morrissey, J.H.1
-
13
-
-
0036780251
-
Clinical translation of angiogenesis inhibitors
-
Kerbel RS, Folkman J. Clinical translation of angiogenesis inhibitors. Nat Rev Cancer 2002;2:727-39.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 727-739
-
-
Kerbel, R.S.1
Folkman, J.2
-
14
-
-
2942615257
-
Antiangiogenic basis of low-dose metronomic chemotherapy
-
Kerbel RS, Kamen BA. Antiangiogenic basis of low-dose metronomic chemotherapy. Nat Rev Cancer 2004;4:423-36.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 423-436
-
-
Kerbel, R.S.1
Kamen, B.A.2
-
15
-
-
0035865363
-
Redefining the target: Chemotherapeutics as antiangiogenics
-
Miller KD, Sweeney CJ, Sledge GW Jr. Redefining the target: chemotherapeutics as antiangiogenics. J Clin Oncol 2001;19:1195-206.
-
(2001)
J Clin Oncol
, vol.19
, pp. 1195-1206
-
-
Miller, K.D.1
Sweeney, C.J.2
Sledge Jr., G.W.3
-
17
-
-
0030857071
-
Regulation of the tissue factor gene
-
Mackman N. Regulation of the tissue factor gene. Thromb Haemost 1997;78:747-54.
-
(1997)
Thromb Haemost
, vol.78
, pp. 747-754
-
-
Mackman, N.1
-
18
-
-
0035174972
-
Specificity, diversity, and convergence in VEGF and TNF-α signaling events leading to tissue factor up-regulation via EGR-1 in endothelial cells
-
Mechtcheriakova D, Schabbauer G, Lucerna M, et al. Specificity, diversity, and convergence in VEGF and TNF-α signaling events leading to tissue factor up-regulation via EGR-1 in endothelial cells. FASEB J 2001;15:230-41
-
(2001)
FASEB J
, vol.15
, pp. 230-241
-
-
Mechtcheriakova, D.1
Schabbauer, G.2
Lucerna, M.3
-
19
-
-
0242353266
-
Tailoring in vitro selection for a picomolar affinity human antibody directed against vascular endothelial growth factor receptor 2 for enhanced neutralizing activity
-
Lu D, Shen J, Vil MD, et al. Tailoring in vitro selection for a picomolar affinity human antibody directed against vascular endothelial growth factor receptor 2 for enhanced neutralizing activity. J Biol Chem 2003;278:43496-507.
-
(2003)
J Biol Chem
, vol.278
, pp. 43496-43507
-
-
Lu, D.1
Shen, J.2
Vil, M.D.3
-
20
-
-
0032893263
-
SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types
-
Fong TA, Shawver LK, Sun L, et al. SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types. Cancer Res 1999;59:99-106.
-
(1999)
Cancer Res
, vol.59
, pp. 99-106
-
-
Fong, T.A.1
Shawver, L.K.2
Sun, L.3
-
21
-
-
0033883776
-
SU6668 is a potent antiangiogenic and antitumor agent that induces regression of established tumors
-
Laird AD, Vajkoczy P, Shawver LK, et al. SU6668 is a potent antiangiogenic and antitumor agent that induces regression of established tumors. Cancer Res 2000;60: 4152-60.
-
(2000)
Cancer Res
, vol.60
, pp. 4152-4160
-
-
Laird, A.D.1
Vajkoczy, P.2
Shawver, L.K.3
-
22
-
-
0037102369
-
ZD6474 inhibits vascular endothelial growth factor signaling, angiogenesis, and tumor growth following oral administration
-
Wedge SR, Ogilvie DJ, Dukes M, et al. ZD6474 inhibits vascular endothelial growth factor signaling, angiogenesis, and tumor growth following oral administration. Cancer Res 2002;62:4645-55.
-
(2002)
Cancer Res
, vol.62
, pp. 4645-4655
-
-
Wedge, S.R.1
Ogilvie, D.J.2
Dukes, M.3
-
23
-
-
12144290647
-
Advances in the structural biology, design and clinical development of VEGF-R kinase inhibitors for the treatment of angiogenesis
-
Manley PW, Bold G, Bruggen J, et al. Advances in the structural biology, design and clinical development of VEGF-R kinase inhibitors for the treatment of angiogenesis. Biochim Biophys Acta 2004;1697:17-27.
-
(2004)
Biochim Biophys Acta
, vol.1697
, pp. 17-27
-
-
Manley, P.W.1
Bold, G.2
Bruggen, J.3
-
24
-
-
2442621619
-
Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer
-
Ferrara N, Hillan KJ, Gerber HP, Novotny W. Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer. Nat Rev Drug Discov 2004;3:391-400.
-
(2004)
Nat Rev Drug Discov
, vol.3
, pp. 391-400
-
-
Ferrara, N.1
Hillan, K.J.2
Gerber, H.P.3
Novotny, W.4
-
25
-
-
0033152286
-
Vascular endothelial cell growth factor-induced tissue factor expression in endothelial cells is mediated by EGR-1
-
Mechtcheriakova D, Wlachos A, Holzmuller H, Binder BR, Hofer E. Vascular endothelial cell growth factor-induced tissue factor expression in endothelial cells is mediated by EGR-1. Blood 1999;93:3811-23.
-
(1999)
Blood
, vol.93
, pp. 3811-3823
-
-
Mechtcheriakova, D.1
Wlachos, A.2
Holzmuller, H.3
Binder, B.R.4
Hofer, E.5
-
26
-
-
0242390332
-
An inhibitory role of the phosphatidylinositol 3-kinase-signaling pathway in vascular endothelial growth factor-induced tissue factor expression
-
Blum S, Issbruker K, Willuweit A, et al. An inhibitory role of the phosphatidylinositol 3-kinase-signaling pathway in vascular endothelial growth factor-induced tissue factor expression. J Biol Chem 2001;276:33428-34.
-
(2001)
J Biol Chem
, vol.276
, pp. 33428-33434
-
-
Blum, S.1
Issbruker, K.2
Willuweit, A.3
-
27
-
-
0036952913
-
Functional role of Egr-1 mediating VEGF-induced tissue factor expression in the retinal capillary endothelium
-
Sassa Y, Hata Y, Murata T, et al. Functional role of Egr-1 mediating VEGF-induced tissue factor expression in the retinal capillary endothelium. Graefes Arch Clin Exp Ophthalmol 2002;240:1003-10.
-
(2002)
Graefes Arch Clin Exp Ophthalmol
, vol.240
, pp. 1003-1010
-
-
Sassa, Y.1
Hata, Y.2
Murata, T.3
-
28
-
-
0023818427
-
The thrombogenic effect of anticancer drug therapy in women with stage II breast cancer
-
Levine MN, Gent M, Hirsh J, et al. The thrombogenic effect of anticancer drug therapy in women with stage II breast cancer. N Engl J Med 1988;318:404-7.
-
(1988)
N Engl J Med
, vol.318
, pp. 404-407
-
-
Levine, M.N.1
Gent, M.2
Hirsh, J.3
-
29
-
-
0036718947
-
Small molecule inhibitors of KDR (VEGFR-2) kinase: An overview of structure activity relationships
-
Boyer SJ. Small molecule inhibitors of KDR (VEGFR-2) kinase: an overview of structure activity relationships. Curr Top Med Chem 2002;2:973-1000.
-
(2002)
Curr Top Med Chem
, vol.2
, pp. 973-1000
-
-
Boyer, S.J.1
-
30
-
-
0036897097
-
Protracted low-dose effects on human endothelial cell proliferation and survival in vitro reveal a selective antiangiogenic window for various chemotherapeutic drugs
-
Bocci G, Nicolaou KC, Kerbel R. Protracted low-dose effects on human endothelial cell proliferation and survival in vitro reveal a selective antiangiogenic window for various chemotherapeutic drugs. Cancer Res 2002;62:6938-43.
-
(2002)
Cancer Res
, vol.62
, pp. 6938-6943
-
-
Bocci, G.1
Nicolaou, K.C.2
Kerbel, R.3
-
31
-
-
9544227474
-
Role of tissue factor in embryonic blood vessel development
-
Carmeliet P, Mackman N, Moons L, et al. Role of tissue factor in embryonic blood vessel development. Nature 1996;383:73-5.
-
(1996)
Nature
, vol.383
, pp. 73-75
-
-
Carmeliet, P.1
Mackman, N.2
Moons, L.3
-
32
-
-
2442700125
-
Regulation of angiogenesis by tissue factor cytoplasmic domain signaling
-
Belting M, Dorrell MI, Sandgren S, et al. Regulation of angiogenesis by tissue factor cytoplasmic domain signaling. Nat Med 2004;10:502-9.
-
(2004)
Nat Med
, vol.10
, pp. 502-509
-
-
Belting, M.1
Dorrell, M.I.2
Sandgren, S.3
-
33
-
-
0032525207
-
Endothelial cells in physiology and in the pathophysiology of vascular disorders
-
Cines DB, Pollak ES, Buck CA, et al. Endothelial cells in physiology and in the pathophysiology of vascular disorders. Blood 1998;91:3527-61.
-
(1998)
Blood
, vol.91
, pp. 3527-3561
-
-
Cines, D.B.1
Pollak, E.S.2
Buck, C.A.3
-
34
-
-
0033586986
-
Vascular-bed-specific hemostasis and hypercoagulable states
-
Rosenberg RD, Aird WC. Vascular-bed-specific hemostasis and hypercoagulable states. N Engl J Med 1999;340:1555-64.
-
(1999)
N Engl J Med
, vol.340
, pp. 1555-1564
-
-
Rosenberg, R.D.1
Aird, W.C.2
-
35
-
-
0024991650
-
Regulation of coagulation by a multivalent Kunitz-type inhibitor
-
Broze GJ Jr, Girard TJ, Novotny WF. Regulation of coagulation by a multivalent Kunitz-type inhibitor. Biochemistry 1990;29:7539-46.
-
(1990)
Biochemistry
, vol.29
, pp. 7539-7546
-
-
Broze Jr., G.J.1
Girard, T.J.2
Novotny, W.F.3
-
36
-
-
0034266013
-
Phase II trial of cisplatin, 5-fluorouracil and folinic acid using a weekly 24-h infusion schedule for locally advanced head and neck cancer: A pharmacokinetic and clinical survey
-
Riva C, Lavieille JP, Schmerber S, Cuisnie O, Reyt E. Phase II trial of cisplatin, 5-fluorouracil and folinic acid using a weekly 24-h infusion schedule for locally advanced head and neck cancer: a pharmacokinetic and clinical survey. Int J Oncol 2000;17:543-9.
-
(2000)
Int J Oncol
, vol.17
, pp. 543-549
-
-
Riva, C.1
Lavieille, J.P.2
Schmerber, S.3
Cuisnie, O.4
Reyt, E.5
-
37
-
-
0041876307
-
Phase 1 trial of fixed dose-rate gemcitabine in combination with carboplatin in chemonaive advanced non-small-cell lung cancer: A Cancer Therapeutics Research Group study
-
Soo RA, Lim HL, Wang LZ, et al. Phase 1 trial of fixed dose-rate gemcitabine in combination with carboplatin in chemonaive advanced non-small-cell lung cancer: a Cancer Therapeutics Research Group study. Cancer Chemother Pharmacol 2003;52:153-8.
-
(2003)
Cancer Chemother Pharmacol
, vol.52
, pp. 153-158
-
-
Soo, R.A.1
Lim, H.L.2
Wang, L.Z.3
-
38
-
-
0037298139
-
Cisplatin induced localized aortic thrombus
-
Apiyasawat S, Wongpraparut N, Jacobson L, Berkowitz H, Jacobs LE, Kotler MN. Cisplatin induced localized aortic thrombus. Echocardiography 2003;20:199-200.
-
(2003)
Echocardiography
, vol.20
, pp. 199-200
-
-
Apiyasawat, S.1
Wongpraparut, N.2
Jacobson, L.3
Berkowitz, H.4
Jacobs, L.E.5
Kotler, M.N.6
-
39
-
-
0037426013
-
Thromboembolic complications during cisplatin-containing chemotherapy for testicular cancer: A problem in the short and possibly also the long term
-
Nuver J, Gietema JA. Thromboembolic complications during cisplatin-containing chemotherapy for testicular cancer: a problem in the short and possibly also the long term. Ned Tijdschr Geneeskd 2003;147:428-30.
-
(2003)
Ned Tijdschr Geneeskd
, vol.147
, pp. 428-430
-
-
Nuver, J.1
Gietema, J.A.2
-
40
-
-
0029866102
-
Surface blebs on apoptotic cells are sites of enhanced procoagulant activity: Implications for coagulation events and antigenic spread in systemic lupus erythematosus
-
Casciola-Rosen L, Rosen A, Petri M, Schlissel M. Surface blebs on apoptotic cells are sites of enhanced procoagulant activity: implications for coagulation events and antigenic spread in systemic lupus erythematosus. Proc Natl Acad Sci U S A 1996;93:1624-9.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 1624-1629
-
-
Casciola-Rosen, L.1
Rosen, A.2
Petri, M.3
Schlissel, M.4
-
41
-
-
0029767998
-
Apoptosis is associated with increased cell surface tissue factor procoagulant activity
-
Greeno EW, Bach RR, Moldow CF. Apoptosis is associated with increased cell surface tissue factor procoagulant activity. Lab Invest 1996;75:281-9.
-
(1996)
Lab Invest
, vol.75
, pp. 281-289
-
-
Greeno, E.W.1
Bach, R.R.2
Moldow, C.F.3
-
42
-
-
13144266696
-
Vascular endothelial growth factor B (VEGF-B) binds to VEGF receptor-1 and regulates plasminogen activator activity in endothelial cells
-
Olofsson B, Korpelainen E, Pepper MS, et al. Vascular endothelial growth factor B (VEGF-B) binds to VEGF receptor-1 and regulates plasminogen activator activity in endothelial cells. Proc Natl Acad Sci U S A 1998; 95:11709-14.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 11709-11714
-
-
Olofsson, B.1
Korpelainen, E.2
Pepper, M.S.3
-
43
-
-
1542466792
-
Annexin II regulates fibrin homeostasis and neoangiogenesis in vivo
-
Ling Q, Jacovina AT, Deora A, et al. Annexin II regulates fibrin homeostasis and neoangiogenesis in vivo. J Clin Invest 2004;113:38-48.
-
(2004)
J Clin Invest
, vol.113
, pp. 38-48
-
-
Ling, Q.1
Jacovina, A.T.2
Deora, A.3
-
44
-
-
1642459357
-
Vascular endothelial growth factor (VEGF) induces rapid prourokinase (pro-uPA) activation on the surface of endothelial cells
-
Prager GW, Breuss JM, Steurer S, Mihaly J, Binder BR. Vascular endothelial growth factor (VEGF) induces rapid prourokinase (pro-uPA) activation on the surface of endothelial cells. Blood 2004;103: 955-62.
-
(2004)
Blood
, vol.103
, pp. 955-962
-
-
Prager, G.W.1
Breuss, J.M.2
Steurer, S.3
Mihaly, J.4
Binder, B.R.5
-
45
-
-
0034897668
-
Synergistic induction of t-PA by vascular endothelial growth factor and basic fibroblast growth factor and localization of t-PA to Weibel-Palade bodies in bovine microvascular endothelial cells
-
Pepper MS, Rosnoblet C, Di Sanza C, Kruithof EK. Synergistic induction of t-PA by vascular endothelial growth factor and basic fibroblast growth factor and localization of t-PA to Weibel-Palade bodies in bovine microvascular endothelial cells. Thromb Haemost 2001;86:702-9.
-
(2001)
Thromb Haemost
, vol.86
, pp. 702-709
-
-
Pepper, M.S.1
Rosnoblet, C.2
Di Sanza, C.3
Kruithof, E.K.4
-
46
-
-
0028968307
-
Vascular endothelial growth factor increases urokinase receptor expression in vascular endothelial cells
-
Mandriota SJ, Seghezzi G, Vassalli JD, et al. Vascular endothelial growth factor increases urokinase receptor expression in vascular endothelial cells. J Biol Chem 1995;270:9709-16.
-
(1995)
J Biol Chem
, vol.270
, pp. 9709-9716
-
-
Mandriota, S.J.1
Seghezzi, G.2
Vassalli, J.D.3
-
47
-
-
0026321129
-
Vascular endothelial growth factor (VEGF) induces plasminogen activators and plasminogen activator inhibitor-1 in microvascular endothelial cells
-
Pepper MS, Ferrara N, Orci L, Montesano R. Vascular endothelial growth factor (VEGF) induces plasminogen activators and plasminogen activator inhibitor-1 in microvascular endothelial cells. Biochem Biophys Res Commun 1991;181:902-6.
-
(1991)
Biochem Biophys Res Commun
, vol.181
, pp. 902-906
-
-
Pepper, M.S.1
Ferrara, N.2
Orci, L.3
Montesano, R.4
-
48
-
-
0038718518
-
Venous thromboembolism and cancer: Risks and outcomes
-
Lee AY, Levine MN. Venous thromboembolism and cancer: risks and outcomes. Circulation 2003;107:I17-I21.
-
(2003)
Circulation
, vol.107
-
-
Lee, A.Y.1
Levine, M.N.2
|