Chemical and pathway proteomics: Powerful tools for oncology drug discovery and personalized health care

Molecular and Cellular Proteomics

Volumn 7, Issue 10, 2008, Pages 1887-1901

  Kruse, Ulrich ^a   Bantscheff, Marcus ^a   Drewes, Gerard ^a   Hopf, Carsten ^a,b  

^a Discovery Technology   (Finland)

^b MANNHEIM UNIVERSITY OF APPLIED SCIENCES   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

3 PHENYLSULFAMOYLCINNAMOHYDROXAMIC ACID; ANTINEOPLASTIC AGENT; BCR ABL PROTEIN; BOSUTINIB; CETUXIMAB; DASATINIB; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; FIBROBLAST GROWTH FACTOR RECEPTOR; FIBROBLAST GROWTH FACTOR RECEPTOR 1; FIBROBLAST GROWTH FACTOR RECEPTOR 3; GEFITINIB; IMATINIB; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PANITUMUMAB; PHOSPHATIDYLINOSITOL 3 KINASE; PLATELET DERIVED GROWTH FACTOR RECEPTOR; SCATTER FACTOR RECEPTOR; STAT5 PROTEIN; THREONINE; TRASTUZUMAB; UNCLASSIFIED DRUG; XL 880;

BREAST CANCER; CANCER INVASION; DOSE RESPONSE; DOWNSTREAM PROCESSING; DRUG BINDING; DRUG MECHANISM; DRUG SENSITIVITY; DRUG TARGETING; ENZYME INHIBITION; GENE AMPLIFICATION; GENE MUTATION; GENE OVEREXPRESSION; HUMAN; LIQUID CHROMATOGRAPHY; LUNG NON SMALL CELL CANCER; MALIGNANT NEOPLASTIC DISEASE; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEOMICS; QUANTITATIVE ANALYSIS; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; ANTINEOPLASTIC AGENTS; CLINICAL TRIALS AS TOPIC; DELIVERY OF HEALTH CARE; DRUG DISCOVERY; HUMANS; MEDICAL ONCOLOGY; NEOPLASMS; PROTEOMICS;

EID: 55049140325     PISSN: 15359476     EISSN: None     Source Type: Journal    
DOI: 10.1074/mcp.R800006-MCP200     Document Type: Review

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