-
1
-
-
0031006603
-
Hypoglycemia in the diabetes control and complications trial the diabetes control and complications trial research group
-
Hypoglycemia in the Diabetes Control and Complications Trial. The Diabetes Control and Complications Trial Research Group. Diabetes, 46, 271-86 (1997)
-
(1997)
Diabetes
, vol.46
, pp. 271-286
-
-
-
2
-
-
0027370108
-
The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
-
The Diabetes Control and Complications Trial Research Group
-
The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group. N Engl J Med, 329, 977-86 (1993)
-
(1993)
N Engl J Med
, vol.329
, pp. 977-986
-
-
-
3
-
-
2342466734
-
Global Prevalence of Diabetes: Estimates for the year 2000 and projections for 2030
-
DOI 10.2337/diacare.27.5.1047
-
Wild, S., G. Roglic, A. Green, R. Sicree & H. King: Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care, 27, 1047-53 (2004) (Pubitemid 38579764)
-
(2004)
Diabetes Care
, vol.27
, Issue.5
, pp. 1047-1053
-
-
Wild, S.1
Roglic, G.2
Green, A.3
Sicree, R.4
King, H.5
-
4
-
-
0033429304
-
Worldwide increase in incidence of Type I diabetes - The analysis of the data on published incidence trends
-
DOI 10.1007/s001250051309
-
Onkamo, P., S. Vaananen, M. Karvonen & J. Tuomilehto: Worldwide increase in incidence of Type I diabetes - the analysis of the data on published incidence trends. Diabetologia, 42, 1395-403 (1999) (Pubitemid 30012309)
-
(1999)
Diabetologia
, vol.42
, Issue.12
, pp. 1395-1403
-
-
Onkamo, P.1
Vaananen, S.2
Karvonen, M.3
Tuomilehto, J.4
-
5
-
-
0025234628
-
Type-I diabetes: A chronic autoimmune disease of human, mouse, and rat
-
Castano, L. & G. S. Eisenbarth: Type-I diabetes: a chronic autoimmune disease of human, mouse, and rat. Annu Rev Immunol, 8, 647-79 (1990) (Pubitemid 20135642)
-
(1990)
Annual Review of Immunology
, vol.8
, pp. 647-679
-
-
Castano, L.1
Eisenbarth, G.S.2
-
6
-
-
0019870959
-
Diabetes in identical twins. A study of 200 pairs
-
DOI 10.1007/BF00262007
-
Barnett, A. H., C. Eff, R. D. Leslie & D. A. Pyke: Diabetes in identical twins. A study of 200 pairs.Diabetologia, 20, 87-93 (1981) (Pubitemid 11138466)
-
(1981)
Diabetologia
, vol.20
, Issue.2
, pp. 87-93
-
-
Barnett, A.H.1
Eff, C.2
Leslie, R.D.G.3
Pyke, D.A.4
-
7
-
-
33745240931
-
A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region
-
DOI 10.1038/ng1800, PII N1800
-
Smyth, D. J., J. D. Cooper, R. Bailey, S. Field, O. Burren, L. J. Smink, C. Guja, C. Ionescu-Tirgoviste, B. Widmer, D. B. Dunger, D. A. Savage, N. M. Walker, D. G. Clayton & J. A. Todd: A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region. Nat Genet, 38, 617-9 (2006) (Pubitemid 43927300)
-
(2006)
Nature Genetics
, vol.38
, Issue.6
, pp. 617-619
-
-
Smyth, D.J.1
Cooper, J.D.2
Bailey, R.3
Field, S.4
Burren, O.5
Smink, L.J.6
Guja, C.7
Ionescu-Tirgoviste, C.8
Widmer, B.9
Dunger, D.B.10
Savage, D.A.11
Walker, N.M.12
Clayton, D.G.13
Todd, J.A.14
-
8
-
-
0029982537
-
Genetic analysis of autoimmune disease
-
DOI 10.1016/S0092-8674(00)81110-1
-
Vyse, T. J. & J. A. Todd: Genetic analysis of autoimmune disease. Cell, 85, 311-8 (1996) (Pubitemid 26160703)
-
(1996)
Cell
, vol.85
, Issue.3
, pp. 311-318
-
-
Vyse, T.J.1
Todd, J.A.2
-
9
-
-
34347341846
-
Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes
-
DOI 10.1038/ng2068, PII NG2068
-
Todd, J. A., N. M. Walker, J. D. Cooper, D. J. Smyth, K. Downes, V. Plagnol, R. Bailey, S. Nejentsev, S. F. Field, F.Payne, C. E. Lowe, J. S. Szeszko, J. P. Hafler, L. Zeitels, J. H. Yang, A. Vella, S. Nutland, H. E. Stevens, H. Schuilenburg, G. Coleman, M. Maisuria, W. Meadows, L. J. Smink, B. Healy, O. S. Burren, A. A. Lam, N. R. Ovington, J. Allen, E. Adlem, H. T. Leung, C. Wallace, J. M. Howson, C. Guja, C. Ionescu-Tirgoviste, M. J. Simmonds, J. M. Heward, S. C. Gough, D. B. Dunger, L. S. Wicker & D. G. Clayton: Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes. Nat Genet, 39, 857-64 (2007) (Pubitemid 47018195)
-
(2007)
Nature Genetics
, vol.39
, Issue.7
, pp. 857-864
-
-
Todd, J.A.1
Walker, N.M.2
Cooper, J.D.3
Smyth, D.J.4
Downes, K.5
Plagnol, V.6
Bailey, R.7
Nejentsev, S.8
Field, S.F.9
Payne, F.10
Lowe, C.E.11
Szeszko, J.S.12
Hafler, J.P.13
Zeitels, L.14
Yang, J.H.M.15
Vella, A.16
Nutland, S.17
Stevens, H.E.18
Schuilenburg, H.19
Coleman, G.20
Maisuria, M.21
Meadows, W.22
Smink, L.J.23
Healy, B.24
Burren, O.S.25
Lam, A.A.C.26
Ovington, N.R.27
Allen, J.28
Adlem, E.29
Leung, H.-T.30
Wallace, C.31
Howson, J.M.M.32
Guja, C.33
Ionescu-Tirgoviste, C.34
Simmonds, M.J.35
Heward, J.M.36
Gough, S.C.L.37
Dunger, D.B.38
Wicker, L.S.39
Clayton, D.G.40
more..
-
10
-
-
0023252262
-
HLA-DQ(β) gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus
-
DOI 10.1038/329599a0
-
Todd, J. A., J. I. Bell & H. O. McDevitt: HLA-DQ beta gene contributes to susceptibility and resistance to insulindependent diabetes mellitus. Nature, 329, 599-604 (1987) (Pubitemid 17140111)
-
(1987)
Nature
, vol.329
, Issue.6140
, pp. 599-604
-
-
Todd, J.A.1
Bell, J.I.2
McDevitt, H.O.3
-
11
-
-
0036068150
-
Asian-specific HLA haplotypes reveal heterogeneity of the contribution of HLA-DR and -DQ haplotypes to susceptibility to type 1 diabetes
-
Kawabata, Y., H. Ikegami, Y. Kawaguchi, T. Fujisawa, M. Shintani, M. Ono, M. Nishino, Y. Uchigata, I. Lee & T. Ogihara: Asian-specific HLA haplotypes reveal heterogeneity of the contribution of HLA-DR and -DQ haplotypes to susceptibility to type 1 diabetes. Diabetes, 51, 545-51 (2002) (Pubitemid 34764816)
-
(2002)
Diabetes
, vol.51
, Issue.2
, pp. 545-551
-
-
Kawabata, Y.1
Ikegami, H.2
Kawaguchi, Y.3
Fujisawa, T.4
Shintani, M.5
Ono, M.6
Nishino, M.7
Uchigata, Y.8
Lee, I.9
Ogihara, T.10
-
13
-
-
0027363484
-
Islet cell autoantigens in insulin-dependent diabetes
-
Atkinson, M. A. & N. K. Maclaren: Islet cell autoantigens in insulin-dependent diabetes. J Clin Invest,92, 1608-16 (1993) (Pubitemid 23304521)
-
(1993)
Journal of Clinical Investigation
, vol.92
, Issue.4
, pp. 1608-1616
-
-
Atkinson, M.A.1
Maclaren, N.K.2
-
14
-
-
0018841766
-
Breeding of a non-obese, diabetic strain of mice
-
Makino, S., K. Kunimoto, Y. Muraoka, Y. Mizushima, K. Katagiri & Y. Tochino: Breeding of a non-obese, diabetic strain of mice. Jikken Dobutsu, 29, 1-13 (1980) (Pubitemid 10185796)
-
(1980)
Experimental Animals
, vol.29
, Issue.1
, pp. 1-13
-
-
Makino, S.1
Kunimoto, K.2
Muraoka, Y.3
-
15
-
-
0026646694
-
The murine autoimmune diabetes model: NOD and related strains
-
Kikutani, H. & S. Makino: The murine autoimmune diabetes model: NOD and related strains. Adv Immunol, 51, 285-322 (1992)
-
(1992)
Adv Immunol
, vol.51
, pp. 285-322
-
-
Kikutani, H.1
Makino, S.2
-
16
-
-
0031423760
-
The nonobese diabetic mouse as a model of autoimmune diabetes: Immune dysregulation gets the NOD
-
DOI 10.1016/S1074-7613(00)80392-1
-
Delovitch, T. L. & B. Singh: The nonobese diabetic mouse as a model of autoimmune diabetes: immune dysregulation gets the NOD. Immunity, 7, 727-38 (1997) (Pubitemid 28064887)
-
(1997)
Immunity
, vol.7
, Issue.6
, pp. 727-738
-
-
Delovitch, T.L.1
Singh, B.2
-
17
-
-
0030769892
-
The NOD mouse
-
DOI 10.1016/S0923-2494(97)87235-5
-
Bach, J. F. & D. Mathis: The NOD mouse. Res Immunol, 148, 285-6 (1997) (Pubitemid 27435910)
-
(1997)
Research in Immunology
, vol.148
, Issue.5
, pp. 285-286
-
-
Bach, J.-F.1
Mathis, D.2
-
18
-
-
0027468997
-
a donors
-
Christianson, S. W., L. D. Shultz & E. H. Leiter: Adoptive transfer of diabetes into immunodeficientNOD-scid/scid mice. Relative contributions of CD4+ and CD8+ T-cells from diabetic versus prediabetic NOD.NON-Thy-1a donors. Diabetes, 42, 44-55 (1993) (Pubitemid 23013794)
-
(1993)
Diabetes
, vol.42
, Issue.1
, pp. 44-55
-
-
Christianson, S.W.1
Shultz, L.D.2
Leiter, E.H.3
-
19
-
-
0025268849
-
Major histocompatibility complex molecules and the beta cell: Inferences from transgenic models
-
Allison, J., L. C. Harrison, I. L. Campbell & J. F. Miller: Major histocompatibility complex molecules and the beta cell: inferences from transgenic models. Curr Top Microbiol Immunol, 156, 121-35 (1990) (Pubitemid 20128715)
-
(1990)
Current Topics in Microbiology and Immunology
, vol.156
, pp. 121-135
-
-
Allison, J.1
Harrison, L.C.2
Campbell, I.L.3
Miller, J.F.A.P.4
-
20
-
-
0023841728
-
Insulin-dependent diabetes mellitus induced in transgenic mice by ectopic expression of class II MHC and interferon-gamma
-
DOI 10.1016/0092-8674(88)90414-X
-
Sarvetnick, N., D. Liggitt, S. L. Pitts, S. E. Hansen & T. A. Stewart: Insulin-dependent diabetes mellitus induced in transgenic mice by ectopic expression of class II MHC and interferon-gamma. Cell, 52, 773-82 (1988) (Pubitemid 18078648)
-
(1988)
Cell
, vol.52
, Issue.5
, pp. 773-782
-
-
Sarvetnick, N.1
Liggitt, D.2
Pitts, S.L.3
Hansen, S.E.4
Stewart, T.A.5
-
21
-
-
0021248957
-
2-Microglobulin induces intracellular transport of human class I transplantation antigen heavy chains in Xenopus laevis oocytes
-
Severinsson, L. & P. A. Peterson: Beta 2- microglobulin induces intracellular transport of human class I transplantation antigen heavy chains in Xenopus laevis oocytes. J Cell Biol, 99, 226-32 (1984) (Pubitemid 14096886)
-
(1984)
Journal of Cell Biology
, vol.99
, Issue.1
, pp. 226-232
-
-
Severinsson, L.1
Peterson, P.A.2
-
22
-
-
0037025990
-
Pancreatic lymph nodes are required for priming of β cell reactive T cells in NOD mice
-
DOI 10.1084/jem.20011353
-
Gagnerault, M. C., J. J. Luan, C. Lotton & F. Lepault: Pancreatic lymph nodes are required for priming of beta cell reactive T cells in NOD mice. J Exp Med, 196, 369-77 (2002) (Pubitemid 34875666)
-
(2002)
Journal of Experimental Medicine
, vol.196
, Issue.3
, pp. 369-377
-
-
Gagnerault, M.-C.1
Luan, J.J.2
Lotton, C.3
Lepault, F.4
-
23
-
-
0036467353
-
In situ β cell death promotes priming of diabetogenic CD8 T lymphocytes
-
Zhang, Y., B. O'Brien, J. Trudeau, R. Tan, P. Santamaria & J. P. Dutz: In situ beta cell death promotes priming of diabetogenic CD8 T lymphocytes. J Immunol, 168, 1466-72 (2002) (Pubitemid 34094520)
-
(2002)
Journal of Immunology
, vol.168
, Issue.3
, pp. 1466-1472
-
-
Zhang, Y.1
O'Brien, B.2
Trudeau, J.3
Tan, R.4
Santamaria, P.5
Dutz, J.P.6
-
24
-
-
0033579875
-
Initiation of autoimmune diabetes by developmentally regulated presentation of islet cell antigens in the pancreatic lymph nodes
-
DOI 10.1084/jem.189.2.331
-
Hoglund, P., J. Mintern, C. Waltzinger, W. Heath, C. Benoist & D. Mathis: Initiation of autoimmune diabetes by developmentally regulated presentation of islet cell antigens in the pancreatic lymph nodes. J Exp Med, 189, 331-9 (1999) (Pubitemid 29063254)
-
(1999)
Journal of Experimental Medicine
, vol.189
, Issue.2
, pp. 331-339
-
-
Hoglund, P.1
Mintern, J.2
Waltzinger, C.3
Heath, W.4
Benoist, C.5
Mathis, D.6
-
25
-
-
0033985277
-
Neonatal β-cell apoptosis: A trigger for autoimmune diabetes?
-
Trudeau, J. D., J. P. Dutz, E. Arany, D. J. Hill, W. E. Fieldus & D. T. Finegood: Neonatal beta-cell apoptosis: a trigger for autoimmune diabetes? Diabetes, 49, 1-7 (2000) (Pubitemid 30022916)
-
(2000)
Diabetes
, vol.49
, Issue.1
, pp. 1-7
-
-
Trudeau, J.D.1
Dutz, J.P.2
Arany, E.3
Hill, D.J.4
Fieldus, W.E.5
Finegood, D.T.6
-
26
-
-
0346366975
-
Cross-Priming of Diabetogenic T Cells Dissociated from CTL-Induced Shedding of β Cell Autoantigens
-
Yamanouchi, J., J. Verdaguer, B. Han, A. Amrani, P. Serra & P. Santamaria: Cross-priming of diabetogenic T cells dissociated from CTL-induced shedding of beta cell autoantigens. J Immunol, 171, 6900-9 (2003) (Pubitemid 37532126)
-
(2003)
Journal of Immunology
, vol.171
, Issue.12
, pp. 6900-6909
-
-
Yamanouchi, J.1
Verdaguer, J.2
Han, B.3
Amrani, A.4
Serra, P.5
Santamaria, P.6
-
27
-
-
0020645067
-
Gene transfer into mouse embryos: Production of transgenic mice by pronuclear injection
-
Gordon, J. W. & F. H. Ruddle: Gene transfer into mouse embryos: production of transgenic mice by pronuclear injection. Methods Enzymol, 101, 411-33 (1983) (Pubitemid 13071063)
-
(1983)
Methods in Enzymology
, vol.101
, pp. 411-433
-
-
Gordon, J.W.1
Ruddle, F.H.2
-
28
-
-
0023002499
-
Germline and somatic mosaicism in transgenic mice
-
DOI 10.1016/0012-1606(86)90068-0
-
Wilkie, T. M., R. L. Brinster & R. D. Palmiter: Germline and somatic mosaicism in transgenic mice. Dev Biol, 118, 9-18 (1986) (Pubitemid 17179009)
-
(1986)
Developmental Biology
, vol.118
, Issue.1
, pp. 9-18
-
-
Wilkie, T.M.1
Brinster, R.L.2
Palmiter, R.D.3
-
29
-
-
0022965278
-
Germ-line transformation of mice
-
Palmiter, R. D. & R. L. Brinster: Germ-line transformation of mice. Annu Rev Genet, 20, 465-99 (1986)
-
(1986)
Annu Rev Genet
, vol.20
, pp. 465-499
-
-
Palmiter, R.D.1
Brinster, R.L.2
-
30
-
-
0019971764
-
Differential regulation of metallothionein-thymidine kinase fusion genes in transgenic mice and their offspring
-
Palmiter, R. D., H. Y. Chen & R. L. Brinster: Differential regulation of metallothionein-thymidine kinase fusion genes in transgenic mice and their offspring. Cell, 29, 701-10 (1982) (Pubitemid 12024856)
-
(1982)
Cell
, vol.29
, Issue.2
, pp. 701-710
-
-
Palmiter, R.D.1
Chen, H.Y.2
Brinster, R.L.3
-
31
-
-
0036210550
-
Regulation of insulin gene transcription
-
DOI 10.1007/s00125-001-0728-y
-
Melloul, D., S. Marshak & E. Cerasi: Regulation of insulin gene transcription. Diabetologia, 45, 309-26 (2002) (Pubitemid 34267353)
-
(2002)
Diabetologia
, vol.45
, Issue.3
, pp. 309-326
-
-
Melloul, D.1
Marshak, S.2
Cerasi, E.3
-
32
-
-
33845544522
-
Comparative analysis of insulin gene promoters: Implications for diabetes research
-
DOI 10.2337/db06-0788
-
Hay, C. W. & K. Docherty: Comparative analysis of insulin gene promoters: implications for diabetes research. Diabetes, 55, 3201-13 (2006) (Pubitemid 44923575)
-
(2006)
Diabetes
, vol.55
, Issue.12
, pp. 3201-3213
-
-
Hay, C.W.1
Docherty, K.2
-
33
-
-
0035313059
-
IFN-γ/TNF-α synergism as the final effector in autoimmune diabetes: A key role for STAT1/IFN regulatory factor-1 pathway in pancreatic/β cell death
-
Suk, K., S. Kim, Y. H. Kim, K. A. Kim, I. Chang, H. Yagita, M. Shong & M. S. Lee: IFN-gamma/TNF-alphasynergism as the final effector in autoimmune diabetes: a key role for STAT1/IFN regulatory factor-1 pathway in pancreatic beta cell death. J Immunol, 166, 4481-9 (2001) (Pubitemid 32233732)
-
(2001)
Journal of Immunology
, vol.166
, Issue.7
, pp. 4481-4489
-
-
Suk, K.1
Kim, S.2
Kim, Y.-H.3
Kim, K.-A.4
Chang, I.5
Yagita, H.6
Shong, M.7
Lee, M.-S.8
-
34
-
-
0033526068
-
In autoimmune diabetes the transition from benign to pernicious insulitis requires an islet cell response to tumor necrosis factor α
-
DOI 10.1084/jem.189.7.1053
-
Pakala, S. V., M. Chivetta, C. B. Kelly & J. D. Katz: In autoimmune diabetes the transition from benign to pernicious insulitis requires an islet cell response to tumor necrosis factor alpha. J Exp Med, 189, 1053-62 (1999) (Pubitemid 29169822)
-
(1999)
Journal of Experimental Medicine
, vol.189
, Issue.7
, pp. 1053-1062
-
-
Pakala, S.V.1
Chivetta, M.2
Kelly, C.B.3
Katz, J.D.4
-
35
-
-
0033561630
-
TNF receptor 1-dependent β cell toxicity as an effector pathway in autoimmune diabetes
-
Kagi, D., A. Ho, B. Odermatt, A. Zakarian, P. S. Ohashi & T. W. Mak: TNF receptor 1-dependent beta cell toxicity as an effector pathway in autoimmune diabetes. J Immunol, 162, 4598-605 (1999) (Pubitemid 29314859)
-
(1999)
Journal of Immunology
, vol.162
, Issue.8
, pp. 4598-4605
-
-
Kagi, D.1
Ho, A.2
Odermatt, B.3
Zakarian, A.4
Ohashi, P.S.5
Mak, T.W.6
-
36
-
-
28244436716
-
Effector function of diabetogenic CD4 Th1 T cell clones: A central role for TNF-α
-
Cantor, J. & K. Haskins: Effector function of diabetogenic CD4 Th1 T cell clones: a central role for TNF-alpha. J Immunol, 175, 7738-45 (2005) (Pubitemid 41713474)
-
(2005)
Journal of Immunology
, vol.175
, Issue.11
, pp. 7738-7745
-
-
Cantor, J.1
Haskins, K.2
-
37
-
-
0035856952
-
Beta-Cell death during progression to diabetes
-
Mathis, D., L. Vence & C. Benoist: beta-Cell death during progression to diabetes. Nature, 414, 792-8 (2001)
-
(2001)
Nature
, vol.414
, pp. 792-798
-
-
Mathis, D.1
Vence, L.2
Benoist, C.3
-
38
-
-
0035668779
-
A choice of death - The signal-transduction of immune-mediated beta-cell apoptosis
-
DOI 10.1007/s001250100021
-
Eizirik, D. L. & T. Mandrup-Poulsen: A choice of death - the signal-transduction of immune-mediated betacell apoptosis. Diabetologia, 44, 2115-33 (2001) (Pubitemid 34015464)
-
(2001)
Diabetologia
, vol.44
, Issue.12
, pp. 2115-2133
-
-
Eizirik, D.L.1
Mandrup-Poulsen, T.2
-
39
-
-
0035656193
-
γ-Interferon signaling in pancreatic β-cells is persistent but can be terminated by overexpression of suppressor of cytokine signaling-1
-
Chong, M. M., H. E. Thomas & T. W. Kay: gamma- Interferon signaling in pancreatic beta-cells is persistent butcan be terminated by overexpression of suppressor of cytokine signaling-1. Diabetes, 50, 2744-51 (2001) (Pubitemid 33733125)
-
(2001)
Diabetes
, vol.50
, Issue.12
, pp. 2744-2751
-
-
Chong, M.M.W.1
Thomas, H.E.2
Kay, T.W.H.3
-
40
-
-
0032531099
-
IFN-γ action on pancreatic beta cells causes class I MHC upregulation but not diabetes
-
Thomas, H. E., J. L. Parker, R. D. Schreiber & T. W. Kay: IFN-gamma action on pancreatic beta cells causes class I MHC upregulation but not diabetes. J Clin Invest, 102, 1249-57 (1998) (Pubitemid 28436285)
-
(1998)
Journal of Clinical Investigation
, vol.102
, Issue.6
, pp. 1249-1257
-
-
Thomas, H.E.1
Parker, J.L.2
Schreiber, R.D.3
Kay, T.W.H.4
-
41
-
-
0036211558
-
IFNγ/TNFα synergism in MHC class II induction: Effect of nicotinamide on MHC class II expression but not on islet-cell apoptosis
-
DOI 10.1007/s00125-001-0755-8
-
Kim, K. A., S. Kim, I. Chang, G. S. Kim, Y. K. Min, M. K. Lee, K. W. Kim & M. S. Lee: IFN gamma/TNF alpha synergism in MHC class II induction: effect of nicotinamide on MHC class II expression but not on isletcell apoptosis. Diabetologia, 45, 385-93 (2002) (Pubitemid 34267361)
-
(2002)
Diabetologia
, vol.45
, Issue.3
, pp. 385-393
-
-
Kim, K.-A.1
Kim, S.2
Chang, I.3
Kim, G.S.4
Min, Y.-K.5
Lee, M.-K.6
Kim, K.-W.7
Lee, M.-S.8
-
42
-
-
0023837232
-
IFN-γ induces islet cell MHC antigens and enhances autoimmune, streptozotocin-induced diabetes in the mouse
-
Campbell, I. L., L. Oxbrow, M. Koulmanda & L. C. Harrison: IFN-gamma induces islet cell MHC antigens and enhances autoimmune, streptozotocin-induced diabetes in the mouse. J Immunol, 140, 1111-6 (1988) (Pubitemid 18088575)
-
(1988)
Journal of Immunology
, vol.140
, Issue.4
, pp. 1111-1116
-
-
Campbell, I.L.1
Oxbrow, L.2
Koulmanda, M.3
Harrison, L.C.4
-
43
-
-
0033178741
-
Evidence that β cell death in the nonobese diabetic mouse is Fas independent
-
Thomas, H. E., R. Darwiche, J. A. Corbett & T. W. Kay: Evidence that beta cell death in the nonobese diabetic mouse is Fas independent. J Immunol, 163, 1562-9 (1999) (Pubitemid 29352780)
-
(1999)
Journal of Immunology
, vol.163
, Issue.3
, pp. 1562-1569
-
-
Thomas, H.E.1
Darwiche, R.2
Corbett, J.A.3
Kay, T.W.H.4
-
44
-
-
0029856723
-
Mouse islet cell lysis mediated by interleukin-1-induced Fas
-
DOI 10.1007/s001250050574
-
Yamada, K., N. Takane-Gyotoku, X. Yuan, F. Ichikawa, C. Inada & K. Nonaka: Mouse islet cell lysis mediated by interleukin-1-induced Fas. Diabetologia, 39, 1306-12 (1996) (Pubitemid 26356058)
-
(1996)
Diabetologia
, vol.39
, Issue.11
, pp. 1306-1312
-
-
Yamada, K.1
Takane-Gyotoku, N.2
Yuan, X.3
Ichikawa, F.4
Inada, C.5
Nonaka, K.6
-
45
-
-
0029989197
-
Inducible nitric oxide synthase (iNOS) in pancreatic islets of nonobese diabetic mice: Identification of iNOS-expressing cells and relationships to cytokines expressed in the islets
-
DOI 10.1210/en.137.5.2093
-
Rabinovitch, A., W. L. Suarez-Pinzon, O. Sorensen & R. C. Bleackley: Inducible nitric oxide synthase (iNOS) in pancreatic islets of nonobese diabetic mice: identification of iNOS- expressing cells and relationships to cytokines expressed in the islets. Endocrinology, 137, 2093-9 (1996) (Pubitemid 26133980)
-
(1996)
Endocrinology
, vol.137
, Issue.5
, pp. 2093-2099
-
-
Rabinovitch, A.1
Suarez-Pinzon, W.L.2
Sorensen, O.3
Bleackley, R.C.4
-
46
-
-
0029817047
-
The role of interleukin-1 in the pathogenesis of IDDM
-
DOI 10.1007/s001250050548
-
Mandrup-Poulsen, T.: The role of interleukin-1 in the pathogenesis of IDDM. Diabetologia, 39, 1005-29 (1996) (Pubitemid 26275930)
-
(1996)
Diabetologia
, vol.39
, Issue.9
, pp. 1005-1029
-
-
Mandrup-Poulsen, T.1
-
47
-
-
0030005411
-
The harmony of the spheres: Inducible nitric oxide synthase and related genes in pancreatic beta cells
-
DOI 10.1007/s001250050528
-
Eizirik, D. L., M. Flodstrom, A. E. Karlsen & N. Welsh: The harmony of the spheres: inducible nitric oxide synthase and related genes in pancreatic beta cells. Diabetologia, 39, 875-90 (1996) (Pubitemid 26249106)
-
(1996)
Diabetologia
, vol.39
, Issue.8
, pp. 875-890
-
-
Eizirik, D.L.1
Flodstrom, M.2
Karlsen, A.E.3
Welsh, N.4
-
48
-
-
0027054055
-
Interleukin 1β induces the formation of nitric oxide by β-cells purified from rodent islets of Langerhans. Evidence for the β-cell as a source and site of action of nitric oxide
-
Corbett, J. A., J. L. Wang, M. A. Sweetland, J. R. Lancaster, Jr. & M. L. McDaniel: Interleukin 1 beta induces the formation of nitric oxide by beta-cells purified from rodent islets of Langerhans. Evidence for the beta-cell as a source and site of action of nitric oxide. J Clin Invest, 90, 2384-91 (1992) (Pubitemid 23010057)
-
(1992)
Journal of Clinical Investigation
, vol.90
, Issue.6
, pp. 2384-2391
-
-
Corbett, J.A.1
Jin Lin Wang2
Sweetland, M.A.3
Lancaster Jr., J.R.4
McDaniel, M.L.5
-
49
-
-
0030937468
-
Apoptosis is the mode of β-cell death responsible for the development of IDDM in the nonobese diabetic (NOD) mouse
-
O'Brien, B. A., B. V. Harmon, D. P. Cameron & D. J. Allan: Apoptosis is the mode of beta-cell death responsible for the development of IDDM in the nonobese diabetic (NOD) mouse. Diabetes, 46, 750-7 (1997) (Pubitemid 27188250)
-
(1997)
Diabetes
, vol.46
, Issue.5
, pp. 750-757
-
-
O'Brien, B.A.1
Harmon, B.V.2
Cameron, D.P.3
Allan, D.J.4
-
50
-
-
0031030653
-
β cell apoptosis in T cell-mediated autoimmune diabetes
-
DOI 10.1073/pnas.94.1.213
-
Kurrer, M. O., S. V. Pakala, H. L. Hanson & J. D. Katz: Beta cell apoptosis in T cell-mediated autoimmune diabetes. Proc Natl Acad Sci U S A, 94, 213-8 (1997) (Pubitemid 27027189)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.1
, pp. 213-218
-
-
Kurrer, M.O.1
Pakala, S.V.2
Hanson, H.L.3
Katz, J.D.4
-
51
-
-
0030800122
-
Requirement of Fas for the development of autoimmune diabetes in nonobese diabetic mice
-
DOI 10.1084/jem.186.4.613
-
Itoh, N., A. Imagawa, T. Hanafusa, M. Waguri, K. Yamamoto, H. Iwahashi, M. Moriwaki, H. Nakajima, J. Miyagawa, M. Namba, S. Makino, S. Nagata, N. Kono & Y. Matsuzawa: Requirement of Fas for the development of autoimmune diabetes in nonobese diabetic mice. J Exp Med, 186, 613-8 (1997) (Pubitemid 27360805)
-
(1997)
Journal of Experimental Medicine
, vol.186
, Issue.4
, pp. 613-618
-
-
Itoh, N.1
Imagawa, A.2
Hanafusa, T.3
Waguri, M.4
Yamamoto, K.5
Iwahashi, H.6
Moriwaki, M.7
Nakajima, H.8
Miyagawa, J.9
Namba, M.10
Makino, S.11
Nagata, S.12
Kono, N.13
Matsuzawa, Y.14
-
52
-
-
0030890721
-
The role of Fas in autoimmune diabetes
-
Chervonsky, A. V., Y. Wang, F. S. Wong, I. Visintin, R. A. Flavell, C. A. Janeway, Jr. & L. A. Matis: The role of Fas in autoimmune diabetes. Cell, 89, 17-24 (1997) (Pubitemid 27180581)
-
(1997)
Cell
, vol.89
, Issue.1
, pp. 17-24
-
-
Chervonsky, A.V.1
Wang, Y.2
Wong, F.S.3
Visintin, I.4
Flavell, R.A.5
Janeway Jr., C.A.6
Matis, L.A.7
-
53
-
-
0029093781
-
Apoptotic cell death triggered by nitric oxide in pancreatic beta-cells
-
Kaneto, H., J. Fujii, H. G. Seo, K. Suzuki, T. Matsuoka, M. Nakamura, H. Tatsumi, Y. Yamasaki, T. Kamada & N. Taniguchi: Apoptotic cell death triggered by nitric oxide in pancreatic beta-cells. Diabetes, 44, 733-8 (1995)
-
(1995)
Diabetes
, vol.44
, pp. 733-738
-
-
Kaneto, H.1
Fujii, J.2
Seo, H.G.3
Suzuki, K.4
Matsuoka, T.5
Nakamura, M.6
Tatsumi, H.7
Yamasaki, Y.8
Kamada, T.9
Taniguchi, N.10
-
54
-
-
0025230418
-
Genes encoding tumor necrosis factor alpha and granzyme A are expressed during development of autoimmune diabetes
-
Held, W., H. R. MacDonald, I. L. Weissman, M. W. Hess & C. Mueller: Genes encoding tumor necrosis factor alpha and granzyme A are expressed during development of autoimmune diabetes. Proc Natl Acad Sci U S A, 87, 2239-43 (1990)
-
(1990)
Proc Natl Acad Sci U S A
, vol.87
, pp. 2239-2243
-
-
Held, W.1
MacDonald, H.R.2
Weissman, I.L.3
Hess, M.W.4
Mueller, C.5
-
55
-
-
0026474808
-
Expression of a tumor necrosis factor alpha transgene in murine pancreatic beta cells results in severe and permanent insulitis without evolution towards diabetes
-
Higuchi, Y., P. Herrera, P. Muniesa, J. Huarte, D. Belin, P. Ohashi, P. Aichele, L. Orci, J. D. Vassalli & P. Vassalli: Expression of a tumor necrosis factor alpha transgene in murine pancreatic beta cells results in severe and permanent insulitis without evolution towards diabetes. J Exp Med, 176, 1719-31 (1992)
-
(1992)
J Exp Med
, vol.176
, pp. 1719-1731
-
-
Higuchi, Y.1
Herrera, P.2
Muniesa, P.3
Huarte, J.4
Belin, D.5
Ohashi, P.6
Aichele, P.7
Orci, L.8
Vassalli, J.D.9
Vassalli, P.10
-
56
-
-
0027207669
-
Transgenic tumor necrosis factor (TNF)-α production in pancreatic islets leads to insulitis, not diabetes: Distinct patterns of inflammation in TNF- α and TNF-β transgenic mice
-
Picarella, D. E., A. Kratz, C. B. Li, N. H. Ruddle & R. A. Flavell: Transgenic tumor necrosis factor (TNF)-alpha production in pancreatic islets leads to insulitis, not diabetes. Distinct patterns of inflammation in TNF-alpha and TNF-beta transgenic mice. J Immunol, 150, 4136-50 (1993) (Pubitemid 23129795)
-
(1993)
Journal of Immunology
, vol.150
, Issue.9
, pp. 4136-4150
-
-
Picarella, D.E.1
Kratz, A.2
Li, C.-B.3
Ruddle, N.H.4
Flavell, R.A.5
-
57
-
-
0025020303
-
Prevention of diabetes in nonobese diabetic mice by tumor necrosis factor (TNF): Similarities between TNF-alpha and interleukin 1
-
Jacob, C. O., S. Aiso, S. A. Michie, H. O. McDevitt & H. Acha-Orbea: Prevention of diabetes in nonobese diabetic mice by tumor necrosis factor (TNF): similarities between TNF-alpha and interleukin 1. Proc Natl Acad Sci U S A, 87, 968-72 (1990)
-
(1990)
Proc Natl Acad Sci U S A
, vol.87
, pp. 968-972
-
-
Jacob, C.O.1
Aiso, S.2
Michie, S.A.3
McDevitt, H.O.4
Acha-Orbea, H.5
-
58
-
-
0032214715
-
Local expression of TNFα in neonatal NOD mice promotes diabetes by enhancing presentation of islet antigens
-
Green, E. A., E. E. Eynon & R. A. Flavell: Local expression of TNFalpha in neonatal NOD mice promotes diabetes by enhancing presentation of islet antigens. Immunity, 9, 733-43 (1998) (Pubitemid 28557601)
-
(1998)
Immunity
, vol.9
, Issue.5
, pp. 733-743
-
-
Green, E.A.1
Eynon, E.E.2
Flaveirti, R.A.3
-
59
-
-
0034677105
-
Neonatal tumor necrosis factor alpha promotes diabetes in nonobese diabetic mice by CD154-independent antigen presentation to CD8 (+) T cells
-
Green, E. A., F. S. Wong, K. Eshima, C. Mora & R. A. Flavell: Neonatal tumor necrosis factor alpha promotes diabetes in nonobese diabetic mice by CD154-independent antigen presentation to CD8 (+) T cells. J Exp Med, 191, 225-38 (2000)
-
(2000)
J Exp Med
, vol.191
, pp. 225-238
-
-
Green, E.A.1
Wong, F.S.2
Eshima, K.3
Mora, C.4
Flavell, R.A.5
-
60
-
-
27644470987
-
The role of TNF-α in the pathogenesis of type 1 diabetes in the nonobese diabetic mouse: Analysis of dendritic cell maturation
-
DOI 10.1073/pnas.0508122102
-
Lee, L. F., B. Xu, S. A. Michie, G. F. Beilhack, T. Warganich, S. Turley & H. O. McDevitt: The role of TNFalpha in the pathogenesis of type 1 diabetes in the nonobese diabetic mouse: analysis of dendritic cell maturation. Proc Natl Acad Sci U S A, 102, 15995-6000 (2005) (Pubitemid 41552856)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.44
, pp. 15995-16000
-
-
Lee, L.-F.1
Xu, B.2
Michie, S.A.3
Beilhack, G.F.4
Warganich, T.5
Turley, S.6
McDevitt, H.O.7
-
61
-
-
0027990811
-
Effect of tumor necrosis factor α on insulin-dependent diabetes mellitus in NOD mice. I. The early development of autoimmunity and the diabetogenic process
-
DOI 10.1084/jem.180.3.995
-
Yang, X. D., R. Tisch, S. M. Singer, Z. A. Cao, R. S. Liblau, R. D. Schreiber & H. O. McDevitt: Effect of tumor necrosis factor alpha on insulin-dependent diabetes mellitus in NOD mice. I. The early development of autoimmunity and the diabetogenic process. J Exp Med, 180, 995-1004 (1994) (Pubitemid 24256612)
-
(1994)
Journal of Experimental Medicine
, vol.180
, Issue.3
, pp. 995-1004
-
-
Yang, X.-D.1
Tisch, R.2
Singer, S.M.3
Cao, Z.A.4
Liblau, R.S.5
Schreiber, R.D.6
McDevitt, H.O.7
-
62
-
-
0029834839
-
Local expression of transgene encoded TNFα in islets prevents autoimmune diabetes in nonobese diabetic (NOD) mice by preventing the development of auto-reactive islet-specific T cells
-
Grewal, I. S., K. D. Grewal, F. S. Wong, D. E. Picarella, C. A. Janeway, Jr. & R. A. Flavell: Local expression of transgene encoded TNF alpha in islets prevents autoimmune diabetes in nonobese diabetic (NOD) mice by preventing the development of auto-reactive isletspecific T cells. J Exp Med, 184, 1963-74 (1996) (Pubitemid 26404486)
-
(1996)
Journal of Experimental Medicine
, vol.184
, Issue.5
, pp. 1963-1974
-
-
Grewal, I.S.1
Grewal, K.D.2
Wong, F.S.3
Picarella, D.E.4
Janeway Jr., C.A.5
Flavell, R.A.6
-
63
-
-
0030890586
-
Cellular responses to interferon-gamma
-
Boehm, U., T. Klamp, M. Groot & J. C. Howard: Cellular responses to interferon-gamma. Annu Rev Immunol, 15, 749-95 (1997)
-
(1997)
Annu Rev Immunol
, vol.15
, pp. 749-795
-
-
Boehm, U.1
Klamp, T.2
Groot, M.3
Howard, J.C.4
-
64
-
-
0029764082
-
+ T-cells in syngeneic islet grafts in NOD mice produce interferon-γ during β-cell destruction
-
Suarez-Pinzon, W., R. V. Rajotte, T. R. Mosmann & A. Rabinovitch: Both CD4+ and CD8+ T-cells in syngeneic islet grafts in NOD mice produce interferongamma during beta-cell destruction. Diabetes, 45, 1350-7 (1996) (Pubitemid 26332897)
-
(1996)
Diabetes
, vol.45
, Issue.10
, pp. 1350-1357
-
-
Suarez-Pinzon, W.1
Rajotte, R.V.2
Mosmann, T.R.3
Rabinovitch, A.4
-
65
-
-
0025108875
-
Loss of pancreatic islet tolerance induced by beta-cell expression of interferon-gamma
-
Sarvetnick, N., J. Shizuru, D. Liggitt, L. Martin, B. McIntyre, A. Gregory, T. Parslow & T. Stewart: Loss of pancreatic islet tolerance induced by beta-cell expression of interferon-gamma. Nature, 346, 844-7 (1990)
-
(1990)
Nature
, vol.346
, pp. 844-847
-
-
Sarvetnick, N.1
Shizuru, J.2
Liggitt, D.3
Martin, L.4
McIntyre, B.5
Gregory, A.6
Parslow, T.7
Stewart, T.8
-
66
-
-
0025905088
-
Prevention of diabetes in NOD mice treated with antibody to murine IFN gamma
-
Debray-Sachs, M., C. Carnaud, C. Boitard, H. Cohen, I. Gresser, P. Bedossa & J. F. Bach: Prevention of diabetes in NOD mice treated with antibody to murine IFN gamma. J Autoimmun, 4, 237-48 (1991)
-
(1991)
J Autoimmun
, vol.4
, pp. 237-248
-
-
Debray-Sachs, M.1
Carnaud, C.2
Boitard, C.3
Cohen, H.4
Gresser, I.5
Bedossa, P.6
Bach, J.F.7
-
67
-
-
0031876997
-
Regulation of MHC class I and II gene transcription: Differences and similarities
-
DOI 10.1007/s002510050425
-
van den Elsen, P. J., S. J. Gobin, M. C. van Eggermond & A. Peijnenburg: Regulation of MHC class I and II gene transcription: differences and similarities. Immunogenetics, 48, 208-21 (1998) (Pubitemid 28352187)
-
(1998)
Immunogenetics
, vol.48
, Issue.3
, pp. 208-221
-
-
Van Den Elsen, P.J.1
Gobin, S.J.P.2
Van Eggermond, M.C.J.A.3
Peijnenburg, A.4
-
68
-
-
0020488534
-
Rat liver thioredoxin and thioredoxin reductase: Purification and characterization
-
Luthman, M. & A. Holmgren: Rat liver thioredoxin and thioredoxin reductase: purification and characterization. Biochemistry, 21, 6628-33 (1982)
-
(1982)
Biochemistry
, vol.21
, pp. 6628-6633
-
-
Luthman, M.1
Holmgren, A.2
-
69
-
-
0030936987
-
Redox regulation of cellular activation
-
DOI 10.1146/annurev.immunol.15.1.351
-
Nakamura, H., K. Nakamura & J. Yodoi: Redox regulation of cellular activation. Annu Rev Immunol, 15, 351-69 (1997) (Pubitemid 27169285)
-
(1997)
Annual Review of Immunology
, vol.15
, pp. 351-369
-
-
Nakamura, H.1
Nakamura, K.2
Yodoi, J.3
-
71
-
-
0032547768
-
Pancreatic β cell-specific expression of thioredoxin, an antioxidative and antiapoptotic protein, prevents autoimmune and streptozotocin-induced diabetes
-
DOI 10.1084/jem.188.8.1445
-
Hotta, M., F. Tashiro, H. Ikegami, H. Niwa, T. Ogihara, J. Yodoi & J. Miyazaki: Pancreatic beta cell-specific expression of thioredoxin, an antioxidative and antiapoptotic protein, prevents autoimmune and streptozotocin-induced diabetes. J Exp Med, 188, 1445-51 (1998) (Pubitemid 28489581)
-
(1998)
Journal of Experimental Medicine
, vol.188
, Issue.8
, pp. 1445-1451
-
-
Hotta, M.1
Tashiro, F.2
Ikegami, H.3
Niwa, H.4
Ogihara, T.5
Yodoi, J.6
Miyazaki, J.-I.7
-
72
-
-
0033973712
-
The heme synthesis and degradation pathways: Role in oxidant sensitivityHeme oxygenase has both pro- and antioxidant properties
-
DOI 10.1016/S0891-5849(99)00223-3, PII S0891584999002233
-
Ryter, S. W. & R. M. Tyrrell: The heme synthesis and degradation pathways: role in oxidant sensitivity. Heme oxygenase has both pro- and antioxidant properties. Free Radic Biol Med, 28, 289-309 (2000) (Pubitemid 30084022)
-
(2000)
Free Radical Biology and Medicine
, vol.28
, Issue.2
, pp. 289-309
-
-
Ryter, S.W.1
Tyrrell, R.M.2
-
73
-
-
33645945014
-
Heme oxygenase- 1/carbon monoxide: From basic science to therapeutic applications
-
Ryter, S. W., J. Alam & A. M. Choi: Heme oxygenase- 1/carbon monoxide: from basic science to therapeutic applications. Physiol Rev, 86, 583-650 (2006)
-
(2006)
Physiol Rev
, vol.86
, pp. 583-650
-
-
Ryter, S.W.1
Alam, J.2
Choi, A.M.3
-
74
-
-
33947326097
-
Long-lasting expression of HO-1 delays progression of type I diabetes in NOD mice
-
Li, M., S. Peterson, D. Husney, M. Inaba, K. Guo, A. Kappas, S. Ikehara & N. G. Abraham: Long-lasting expression of HO-1 delays progression of type I diabetes in NOD mice. Cell Cycle, 6, 567-71 (2007) (Pubitemid 46440429)
-
(2007)
Cell Cycle
, vol.6
, Issue.5
, pp. 567-571
-
-
Li, M.1
Peterson, S.2
Husney, D.3
Inaba, M.4
Guo, K.5
Kappas, A.6
Ikehara, S.7
Abraham, N.G.8
-
75
-
-
34248182498
-
Systemic expression of heme oxygenase-1 ameliorates type 1 diabetes in NOD mice
-
Hu, C. M., H. H. Lin, M. T. Chiang, P. F. Chang & L. Y. Chau: Systemic expression of heme oxygenase-1 ameliorates type 1 diabetes in NOD mice. Diabetes, 56, 1240-7 (2007)
-
(2007)
Diabetes
, vol.56
, pp. 1240-1247
-
-
Hu, C.M.1
Lin, H.H.2
Chiang, M.T.3
Chang, P.F.4
Chau, L.Y.5
-
76
-
-
0037008769
-
Suppressor of cytokine signaling-1 regulates the sensitivity of pancreatic β cells to tumor necrosis factor
-
DOI 10.1074/jbc.M110214200
-
Chong, M. M., H. E. Thomas & T. W. Kay: Suppressor of cytokine signaling-1 regulates the sensitivity of pancreatic beta cells to tumor necrosis factor. J Biol Chem, 277, 27945-52 (2002) (Pubitemid 34966742)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.31
, pp. 27945-27952
-
-
Chong, M.M.W.1
Thomas, H.E.2
Kay, T.W.H.3
-
77
-
-
0036913215
-
β cells are responsible for CXCR3-mediated t-cell infiltration in insulitis
-
DOI 10.1038/nm792
-
Frigerio, S., T. Junt, B. Lu, C. Gerard, U. Zumsteg, G. A. Hollander & L. Piali: Beta cells are responsible for CXCR3-mediated T-cell infiltration in insulitis. Nat Med, 8, 1414-20 (2002) (Pubitemid 36024137)
-
(2002)
Nature Medicine
, vol.8
, Issue.12
, pp. 1414-1420
-
-
Frigerio, S.1
Junt, T.2
Lu, B.3
Gerard, C.4
Zumsteg, U.5
Hollander, G.A.6
Piali, L.7
-
78
-
-
0035966006
-
A comprehensive analysis of cytokine-induced and nuclear factor-kappa B-dependent genes in primary ratpancreatic beta-cells
-
Cardozo, A. K., H. Heimberg, Y. Heremans, R. Leeman, B. Kutlu, M. Kruhoffer, T. Orntoft & D. L. Eizirik: A comprehensive analysis of cytokine-induced and nuclear factor-kappa B-dependent genes in primary ratpancreatic beta-cells. J Biol Chem, 276, 48879-86 (2001)
-
(2001)
J Biol Chem
, vol.276
, pp. 48879-48886
-
-
Cardozo, A.K.1
Heimberg, H.2
Heremans, Y.3
Leeman, R.4
Kutlu, B.5
Kruhoffer, M.6
Orntoft, T.7
Eizirik, D.L.8
-
79
-
-
0030839112
-
A new protein containing an SH2 domain that inhibits JAK kinases
-
DOI 10.1038/43213
-
Endo, T. A., M. Masuhara, M. Yokouchi, R. Suzuki, H. Sakamoto, K. Mitsui, A. Matsumoto, S. Tanimura, M. Ohtsubo, H. Misawa, T. Miyazaki, N. Leonor, T. Taniguchi, T. Fujita, Y. Kanakura, S. Komiya & A. Yoshimura: A new protein containing an SH2 domain that inhibits JAK kinases. Nature, 387, 921-4 (1997) (Pubitemid 27289595)
-
(1997)
Nature
, vol.387
, Issue.6636
, pp. 921-924
-
-
Endo, T.A.1
Masuhara, M.2
Yokouchi, M.3
Suzuki, R.4
Sakamoto, H.5
Mitsui, K.6
Matsumoto, A.7
Tanimura, S.8
Ohtsubo, M.9
Misawa, H.10
Miyazaki, T.11
Leonor, N.12
Taniguchi, T.13
Fujita, T.14
Kanakura, Y.15
Komiya, S.16
Yoshimura, A.17
-
80
-
-
2142761669
-
+ T Cell-Mediated Autoimmune Destruction
-
Chong, M. M., Y. Chen, R. Darwiche, N. L. Dudek, W. Irawaty, P. Santamaria, J. Allison, T. W. Kay & H. E. Thomas: Suppressor of cytokine signaling-1 overexpression protects pancreatic beta cells from CD8+ T cell-mediated autoimmune destruction. J Immunol, 172, 5714-21 (2004) (Pubitemid 38542076)
-
(2004)
Journal of Immunology
, vol.172
, Issue.9
, pp. 5714-5721
-
-
Chong, M.M.W.1
Chen, Y.2
Darwiche, R.3
Dudek, N.L.4
Irawaty, W.5
Santamaria, P.6
Allison, J.7
Kay, T.W.H.8
Thomas, H.E.9
-
81
-
-
0028354067
-
Immunoregulatory and cytokine imbalances in the pathogenesis of IDDM: Therapeutic intervention by immunostimulation?
-
Rabinovitch, A.: Immunoregulatory and cytokine imbalances in the pathogenesis of IDDM. Therapeutic intervention by immunostimulation? Diabetes, 43, 613-21 (1994) (Pubitemid 24138771)
-
(1994)
Diabetes
, vol.43
, Issue.5
, pp. 613-621
-
-
Rabinovitch, A.1
-
82
-
-
0029030964
-
T helper cell subsets in insulin-dependent diabetes
-
Katz, J. D., C. Benoist & D. Mathis: T helper cell subsets in insulin-dependent diabetes. Science, 268, 1185-8 (1995)
-
(1995)
Science
, vol.268
, pp. 1185-1188
-
-
Katz, J.D.1
Benoist, C.2
Mathis, D.3
-
83
-
-
0027170778
-
+ T cells of non-obese diabetic mice
-
Shimizu, J., O. Kanagawa & E. R. Unanue: Presentation of beta-cell antigens to CD4+ and CD8+ T cells of non-obese diabetic mice. J Immunol, 151, 1723-30 (1993) (Pubitemid 23219311)
-
(1993)
Journal of Immunology
, vol.151
, Issue.3
, pp. 1723-1730
-
-
Shimizu, J.1
Kanagawa, O.2
Unanue, E.R.3
-
84
-
-
0025009870
-
Acceleration of diabetes in young NOD mice with a CD4+ islet-specific T cell clone
-
Haskins, K. & M. McDuffie: Acceleration of diabetes in young NOD mice with a CD4+ islet-specific T cell clone. Science, 249, 1433-6 (1990)
-
(1990)
Science
, vol.249
, pp. 1433-1436
-
-
Haskins, K.1
McDuffie, M.2
-
85
-
-
0027272228
-
Interleukin 4 reverses T cell proliferative unresponsiveness and prevents the onset of diabetes in nonobese diabetic mice
-
Rapoport, M. J., A. Jaramillo, D. Zipris, A. H. Lazarus, D. V. Serreze, E. H. Leiter, P. Cyopick, J. S. Danska & T. L. Delovitch: Interleukin 4 reverses T cell proliferative unresponsiveness and prevents the onset of diabetes in nonobese diabetic mice. J Exp Med, 178, 87-99 (1993) (Pubitemid 23173245)
-
(1993)
Journal of Experimental Medicine
, vol.178
, Issue.1
, pp. 87-99
-
-
Rapoport, M.J.1
Jaramillo, A.2
Zipris, D.3
Lazarus, A.H.4
Serreze, D.V.5
Leiter, E.H.6
Cyopick, P.7
Danska, J.S.8
Delovitch, T.L.9
-
86
-
-
0028222756
-
Recombinant human IL-10 prevents the onset of diabetes in the nonobese diabetic mouse
-
DOI 10.1006/clin.1994.1068
-
Pennline, K. J., E. Roque-Gaffney & M. Monahan: Recombinant human IL-10 prevents the onset of diabetes in the nonobese diabetic mouse. Clin Immunol Immunopathol, 71, 169-75 (1994) (Pubitemid 24147233)
-
(1994)
Clinical Immunology and Immunopathology
, vol.71
, Issue.2
, pp. 169-175
-
-
Pennline, K.J.1
Roque-Gaffney, E.R.2
Monahan, M.3
-
87
-
-
0029838995
-
Pancreatic expression of interleukin-4 abrogates insulitis and autoimmune diabetes in nonobese diabetic (NOD) mice
-
Mueller, R., T. Krahl & N. Sarvetnick: Pancreatic expression of interleukin-4 abrogates insulitis and autoimmune diabetes in nonobese diabetic (NOD) mice. J Exp Med, 184, 1093-9 (1996) (Pubitemid 26313566)
-
(1996)
Journal of Experimental Medicine
, vol.184
, Issue.3
, pp. 1093-1099
-
-
Mueller, R.1
Krahl, T.2
Sarvetnick, N.3
-
88
-
-
0030879734
-
Mechanism underlying counterregulation of autoimmune diabetes by IL-4
-
DOI 10.1016/S1074-7613(00)80362-3
-
Mueller, R., L. M. Bradley, T. Krahl & N. Sarvetnick: Mechanism underlying counterregulation of autoimmune diabetes by IL-4. Immunity, 7, 411-8 (1997) (Pubitemid 27446015)
-
(1997)
Immunity
, vol.7
, Issue.3
, pp. 411-418
-
-
Mueller, R.1
Bradley, L.M.2
Krahl, T.3
Sarvetnick, N.4
-
89
-
-
0035122430
-
IL-4 triggers autoimmune diabetes by increasing self-antigen presentation within the pancreatic Islets
-
Falcone, M., B. Yeung, L. Tucker, E. Rodriguez, T. Krahl & N. Sarvetnick: IL-4 triggers autoimmune diabetes by increasing self-antigen presentation within the pancreatic Islets. Clin Immunol, 98, 190-9 (2001)
-
(2001)
Clin Immunol
, vol.98
, pp. 190-199
-
-
Falcone, M.1
Yeung, B.2
Tucker, L.3
Rodriguez, E.4
Krahl, T.5
Sarvetnick, N.6
-
90
-
-
33644872062
-
The natural killer T lymphocyte: A player in the complex regulation of autoimmune diabetes in nonobese diabetic mice
-
Cardell, S. L.: The natural killer T lymphocyte: a player in the complex regulation of autoimmune diabetes in nonobese diabetic mice. Clin Exp Immunol, 143, 194-202 (2006)
-
(2006)
Clin Exp Immunol
, vol.143
, pp. 194-202
-
-
Cardell, S.L.1
-
91
-
-
33746330703
-
Transforming growth factor-β and T-cell-mediated immunoregulation in the control of autoimmune diabetes
-
DOI 10.1111/j.0105-2896.2006.00410.x
-
You, S., N. Thieblemont, M. A. Alyanakian, J. F. Bach & L. Chatenoud: Transforming growth factor-beta and Tcell- mediated immunoregulation in the control of autoimmune diabetes. Immunol Rev, 212, 185-202 (2006) (Pubitemid 44116709)
-
(2006)
Immunological Reviews
, vol.212
, pp. 185-202
-
-
You, S.1
Thieblemont, N.2
Alyanakian, M.-A.3
Bach, J.-F.4
Chatenoud, L.5
-
92
-
-
0026799402
-
Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease
-
Shull, M. M., I. Ormsby, A. B. Kier, S. Pawlowski, R. J. Diebold, M. Yin, R. Allen, C. Sidman, G. Proetzel, D. Calvin & et al.: Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease. Nature, 359, 693-9 (1992)
-
(1992)
Nature
, vol.359
, pp. 693-699
-
-
Shull, M.M.1
Ormsby, I.2
Kier, A.B.3
Pawlowski, S.4
Diebold, R.J.5
Yin, M.6
Allen, R.7
Sidman, C.8
Proetzel, G.9
Calvin, D.10
-
93
-
-
0023746462
-
Transforming growth factorbeta 1 modulates the expression of class II histocompatibility antigens on human cells
-
Czarniecki, C. W., H. H. Chiu, G. H. Wong, S. M. McCabe & M. A. Palladino: Transforming growth factorbeta 1 modulates the expression of class II histocompatibility antigens on human cells. J Immunol, 140, 4217-23 (1988)
-
(1988)
J Immunol
, vol.140
, pp. 4217-4223
-
-
Czarniecki, C.W.1
Chiu, H.H.2
Wong, G.H.3
McCabe, S.M.4
Palladino, M.A.5
-
94
-
-
0029149596
-
Control of CD4 effector fate: Transforminggrowth factor beta 1 and interleukin 2 synergize to prevent apoptosis and promote effector expansion
-
Zhang, X., L. Giangreco, H. E. Broome, C. M. Dargan & S. L. Swain: Control of CD4 effector fate: transforminggrowth factor beta 1 and interleukin 2 synergize to prevent apoptosis and promote effector expansion. J Exp Med, 182, 699-709 (1995)
-
(1995)
J Exp Med
, vol.182
, pp. 699-709
-
-
Zhang, X.1
Giangreco, L.2
Broome, H.E.3
Dargan, C.M.4
Swain, S.L.5
-
95
-
-
0032056347
-
TGF-β1 alters APC preference, polarizing islet antigen responses toward a Th2 phenotype
-
DOI 10.1016/S1074-7613(00)80565-8
-
King, C., J. Davies, R. Mueller, M. S. Lee, T. Krahl, B. Yeung, E. O'Connor & N. Sarvetnick: TGF-beta1 alters APC preference, polarizing islet antigen responses toward a Th2 phenotype. Immunity, 8, 601-13 (1998) (Pubitemid 28264751)
-
(1998)
Immunity
, vol.8
, Issue.5
, pp. 601-613
-
-
King, C.1
Davies, J.2
Mueller, R.3
Lee, M.-S.4
Krahl, T.5
Yeung, B.6
O'Connor, E.7
Sarvetnick, N.8
-
96
-
-
1842480959
-
+ regulatory T cells responsible for protection against diabetes
-
DOI 10.1073/pnas.0400810101
-
Peng, Y., Y. Laouar, M. O. Li, E. A. Green & R. A. Flavell: TGF-beta regulates in vivo expansion of Foxp3- expressing CD4+CD25+ regulatory T cells responsible for protection against diabetes. Proc Natl Acad Sci U S A, 101, 4572-7 (2004) (Pubitemid 38437452)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.13
, pp. 4572-4577
-
-
Peng, Y.1
Laouar, Y.2
Li, M.O.3
Green, E.A.4
Flavell, R.A.5
-
97
-
-
0029978038
-
Checkpoints in the progression of autoimmune disease: Lessons from diabetes models
-
DOI 10.1073/pnas.93.6.2260
-
Andre, I., A. Gonzalez, B. Wang, J. Katz, C. Benoist & D. Mathis: Checkpoints in the progression of autoimmune disease: lessons from diabetes models. Proc Natl Acad Sci U S A, 93, 2260-3 (1996) (Pubitemid 26104338)
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, Issue.6
, pp. 2260-2263
-
-
Andre, I.1
Gonzalez, A.2
Wang, B.3
Katz, J.4
Benoist, C.5
Mathis, D.6
-
98
-
-
0025553819
-
Flow cytometric enumeration of mononuclear cell populations infiltrating the islets of Langerhans in prediabetic NOD mice: Development of a model of autoimmune insulitis for type i diabetes
-
Jarpe, A. J., M. R. Hickman, J. T. Anderson, W. E. Winter & A. B. Peck: Flow cytometric enumeration of mononuclear cell populations infiltrating the islets of Langerhans in prediabetic NOD mice: development of a model of autoimmune insulitis for type I diabetes. Reg Immunol, 3, 305-17 (1990)
-
(1990)
Reg Immunol
, vol.3
, pp. 305-317
-
-
Jarpe, A.J.1
Hickman, M.R.2
Anderson, J.T.3
Winter, W.E.4
Peck, A.B.5
-
99
-
-
0023905731
-
+ T cell subsets are required for the transfer of diabetes in nonobese diabetic mice
-
Miller, B. J., M. C. Appel, J. J. O'Neil & L. S. Wicker: Both the Lyt-2+ and L3T4+ T cell subsets are required for the transfer of diabetes in nonobese diabetic mice. J Immunol, 140, 52-8 (1988) (Pubitemid 18050680)
-
(1988)
Journal of Immunology
, vol.140
, Issue.1
, pp. 52-58
-
-
Miller, B.J.1
Appel, M.C.2
O'Neil, J.J.3
Wicker, L.S.4
-
100
-
-
0023544492
-
+ cells
-
Bendelac, A., C. Carnaud, C. Boitard & J. F. Bach: Syngeneic transfer of autoimmune diabetes from diabeticNOD mice to healthy neonates. Requirement for both L3T4+ and Lyt-2+ T cells. J Exp Med, 166, 823-32 (1987) (Pubitemid 18024228)
-
(1987)
Journal of Experimental Medicine
, vol.166
, Issue.4
, pp. 823-832
-
-
Bendelac, A.1
Carnaud, C.2
Boitard, C.3
Bach, J.F.4
-
101
-
-
0026539665
-
CD8 T cells are not required for islet destruction induced by a CD4+ islet-specific T-cell clone
-
Bradley, B. J., K. Haskins, F. G. La Rosa & K. J. Lafferty: CD8 T cells are not required for islet destruction induced by a CD4+ islet-specific T-cell clone. Diabetes, 41, 1603-8 (1992)
-
(1992)
Diabetes
, vol.41
, pp. 1603-1608
-
-
Bradley, B.J.1
Haskins, K.2
La Rosa, F.G.3
Lafferty, K.J.4
-
102
-
-
0028006398
-
β2-Microglobulin-deficient NOD mice do not develop insulitis or diabetes
-
Wicker, L. S., E. H. Leiter, J. A. Todd, R. J. Renjilian, E. Peterson, P. A. Fischer, P. L. Podolin, M. Zijlstra, R. Jaenisch & L. B. Peterson: Beta 2-microglobulin-deficient NOD mice do not develop insulitis or diabetes. Diabetes, 43, 500-4 (1994) (Pubitemid 24064260)
-
(1994)
Diabetes
, vol.43
, Issue.3
, pp. 500-504
-
-
Wicker, L.S.1
Leiter, E.H.2
Todd, J.A.3
Renjilian, R.J.4
Peterson, E.5
Fischer, P.A.6
Podolin, P.L.7
Zijlstra, M.8
Jaenisch, R.9
Peterson, L.B.10
-
103
-
-
0028123012
-
2-microglobulin- deficient non-obese diabetic mice
-
Sumida, T., M. Furukawa, A. Sakamoto, T. Namekawa, T. Maeda, M. Zijlstra, I. Iwamoto, T. Koike, S. Yoshida, H. Tomioka & et al.: Prevention of insulitis and diabetes in beta 2-microglobulin-deficient non-obese diabetic mice. Int Immunol, 6, 1445-9 (1994) (Pubitemid 24296861)
-
(1994)
International Immunology
, vol.6
, Issue.9
, pp. 1445-1449
-
-
Sumida, T.1
Furukawa, M.2
Sakamoto, A.3
Namekawa, T.4
Maeda, T.5
Zijlstra, M.6
Iwamoto, I.7
Koike, T.8
Yoshida, S.9
Tomioka, H.10
Taniguchi, M.11
-
104
-
-
0027979956
-
Major histocompatibility complex class I-deficient NOD-B2mnull mice are diabetes and insulitis resistant
-
Serreze, D. V., E. H. Leiter, G. J. Christianson, D. Greiner & D. C. Roopenian: Major histocompatibility complex class I-deficient NOD-B2mnull mice are diabetes and insulitis resistant. Diabetes, 43, 505-9 (1994)
-
(1994)
Diabetes
, vol.43
, pp. 505-509
-
-
Serreze, D.V.1
Leiter, E.H.2
Christianson, G.J.3
Greiner, D.4
Roopenian, D.C.5
-
105
-
-
0027367830
-
Major histocompatibility complex class I molecules are required for the development of insulitis in non-obese diabetic mice
-
DOI 10.1002/eji.1830231244
-
Katz, J., C. Benoist & D. Mathis: Major histocompatibility complex class I molecules are required for the development of insulitis in non-obese diabetic mice. Eur J Immunol, 23, 3358-60 (1993) (Pubitemid 23353790)
-
(1993)
European Journal of Immunology
, vol.23
, Issue.12
, pp. 3358-3360
-
-
Katz, J.1
Benoist, C.2
Mathis, D.3
-
106
-
-
0035029840
-
Adenovirus early region 3 (E3) immunomodulatory genes decrease the incidence of autoimmune diabetes in NOD mice
-
Efrat, S., D. Serreze, A. Svetlanov, C. M. Post, E. A. Johnson, K. Herold & M. Horwitz: Adenovirus early region 3 (E3) immunomodulatory genes decrease the incidence of autoimmune diabetes in NOD mice. Diabetes, 50, 980-4 (2001) (Pubitemid 32374527)
-
(2001)
Diabetes
, vol.50
, Issue.5
, pp. 980-984
-
-
Efrat, S.1
Serreze, D.2
Svetlanov, A.3
Post, C.M.4
Johnson, E.A.5
Herold, K.6
Horwitz, M.7
-
107
-
-
1842289172
-
Reduced incidence and delayed onset of diabetes in perforin-deficient nonobese diabetic mice
-
DOI 10.1084/jem.186.7.989
-
Kagi, D., B. Odermatt, P. Seiler, R. M. Zinkernagel, T. W. Mak & H. Hengartner: Reduced incidence anddelayed onset of diabetes in perforin-deficient nonobese diabetic mice. J Exp Med, 186, 989-97 (1997) (Pubitemid 27441144)
-
(1997)
Journal of Experimental Medicine
, vol.186
, Issue.7
, pp. 989-997
-
-
Kagi, D.1
Odermatt, B.2
Seiler, P.3
Zinkernagel, R.M.4
Mak, T.W.5
Hengartner, H.6
-
108
-
-
0032526566
-
The role of lymphocyte subsets in accelerated diabetes in nonobese diabetic-rat insulin promoter-B7-1 (NOD-RIP-B7-1) mice
-
DOI 10.1084/jem.187.12.1985
-
Wong, F. S., I. Visintin, L. Wen, J. Granata, R. Flavell & C. A. Janeway: The role of lymphocyte subsets in accelerated diabetes in nonobese diabetic-rat insulin promoter-B7-1 (NOD-RIP-B7-1) mice. J Exp Med, 187, 1985-93 (1998) (Pubitemid 28285568)
-
(1998)
Journal of Experimental Medicine
, vol.187
, Issue.12
, pp. 1985-1993
-
-
Wong, F.S.1
Visintin, I.2
Wen, L.3
Granata, J.4
Flavell, R.5
Janeway Jr., C.A.6
-
109
-
-
21344441928
-
The influence of the major histocompatibility complex on development of autoimmune diabetes in RIP=B7.1 mice
-
DOI 10.2337/diabetes.54.7.2032
-
Wong, F. S., W. Du, I. J. Thomas & L. Wen: The influence of the major histocompatibility complex ondevelopment of autoimmune diabetes in RIP-B7.1 mice. Diabetes, 54, 2032-40 (2005) (Pubitemid 40911266)
-
(2005)
Diabetes
, vol.54
, Issue.7
, pp. 2032-2040
-
-
Susan Wong, F.1
Du, W.2
Thomas, I.J.3
Wen, L.4
-
110
-
-
0029558631
-
Pancreatic expression of B7 co-stimulatory molecules in the non-obese diabetic mouse
-
Stephens, L. A. & T. W. Kay: Pancreatic expression of B7 co-stimulatory molecules in the non-obese diabetic mouse. Int Immunol, 7, 1885-95 (1995) (Pubitemid 26003695)
-
(1995)
International Immunology
, vol.7
, Issue.12
, pp. 1885-1895
-
-
Stephens, L.A.1
Kay, T.W.H.2
-
111
-
-
34247884612
-
The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection
-
DOI 10.1038/ni1443, PII NI1443
-
Sharpe, A. H., E. J. Wherry, R. Ahmed & G. J. Freeman: The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection. Nat Immunol, 8, 239-45 (2007) (Pubitemid 46745373)
-
(2007)
Nature Immunology
, vol.8
, Issue.3
, pp. 239-245
-
-
Sharpe, A.H.1
Wherry, E.J.2
Ahmed, R.3
Freeman, G.J.4
-
113
-
-
2442461055
-
The roles of the new negative T cell costimulatory pathways in regulating autoimmunity
-
DOI 10.1016/S1074-7613(04)00116-5, PII S1074761304001165
-
Khoury, S. J. & M. H. Sayegh: The roles of the new negative T cell costimulatory pathways in regulating autoimmunity. Immunity, 20, 529-38 (2004) (Pubitemid 38638123)
-
(2004)
Immunity
, vol.20
, Issue.5
, pp. 529-538
-
-
Khoury, S.J.1
Sayegh, M.H.2
-
114
-
-
0042877332
-
Immune regulation by novel costimulatory molecules
-
DOI 10.1385/IR:28:1:39
-
Dong, C., R. I. Nurieva & D. V. Prasad: Immune regulation by novel costimulatory molecules. Immunol Res, 28, 39-48 (2003) (Pubitemid 37088541)
-
(2003)
Immunologic Research
, vol.28
, Issue.1
, pp. 39-48
-
-
Dong, C.1
Nurieva, R.I.2
Prasad, D.V.R.3
-
115
-
-
33751552197
-
Insulin-induced remission in new-onset NOD mice is maintained by the PD-1-PD-L1 pathway
-
DOI 10.1084/jem.20061577
-
Fife, B. T., I. Guleria, M. Gubbels Bupp, T. N. Eagar, Q. Tang, H. Bour-Jordan, H. Yagita, M. Azuma, M. H.Sayegh & J. A. Bluestone: Insulin-induced remission in new-onset NOD mice is maintained by the PD-1-PD-L1 pathway. J Exp Med, 203, 2737-47 (2006) (Pubitemid 44833349)
-
(2006)
Journal of Experimental Medicine
, vol.203
, Issue.12
, pp. 2737-2747
-
-
Fife, B.T.1
Guleria, I.2
Bupp, M.G.3
Eagar, T.N.4
Tang, Q.5
Bour-Jordan, H.6
Yagita, H.7
Azuma, M.8
Sayegh, M.H.9
Bluestone, J.A.10
-
116
-
-
33645846313
-
Tissue expression of PD-L1 mediates peripheral T cell tolerance
-
Keir, M. E., S. C. Liang, I. Guleria, Y. E. Latchman, A. Qipo, L. A. Albacker, M. Koulmanda, G. J. Freeman, M. H. Sayegh & A. H. Sharpe: Tissue expression of PD-L1 mediates peripheral T cell tolerance. J Exp Med, 203, 883-95 (2006)
-
(2006)
J Exp Med
, vol.203
, pp. 883-895
-
-
Keir, M.E.1
Liang, S.C.2
Guleria, I.3
Latchman, Y.E.4
Qipo, A.5
Albacker, L.A.6
Koulmanda, M.7
Freeman, G.J.8
Sayegh, M.H.9
Sharpe, A.H.10
-
117
-
-
0030300154
-
The complexities of T-Cell Co-stimulation: CD28 and beyond
-
Sperling, A. I. & J. A. Bluestone: The complexities of T-cell co-stimulation: CD28 and beyond. Immunol Rev, 153, 155-82 (1996) (Pubitemid 27010767)
-
(1996)
Immunological Reviews
, Issue.153
, pp. 155-182
-
-
Sperling, A.I.1
Bluestone, J.A.2
-
118
-
-
0029899783
-
CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells
-
DOI 10.1084/jem.183.6.2533
-
Krummel, M. F. & J. P. Allison: CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells. J Exp Med, 183, 2533-40 (1996) (Pubitemid 26192363)
-
(1996)
Journal of Experimental Medicine
, vol.183
, Issue.6
, pp. 2533-2540
-
-
Krummel, M.F.1
Allison, J.P.2
-
119
-
-
0029120245
-
CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation
-
Krummel, M. F. & J. P. Allison: CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation. J Exp Med, 182, 459-65 (1995)
-
(1995)
J Exp Med
, vol.182
, pp. 459-465
-
-
Krummel, M.F.1
Allison, J.P.2
-
120
-
-
0036232603
-
The role of CTLA-4 in induction and maintenance of peripheral T cell tolerance
-
DOI 10.1002/1521-4141(200204)32:4<972::AID-IMMU972>3.0.CO;2-M
-
Eagar, T. N., N. J. Karandikar, J. A. Bluestone & S. D. Miller: The role of CTLA-4 in induction and maintenance of peripheral T cell tolerance. Eur J Immunol, 32, 972-81 (2002) (Pubitemid 34428812)
-
(2002)
European Journal of Immunology
, vol.32
, Issue.4
, pp. 972-981
-
-
Eagar, T.N.1
Karandikar, N.J.2
Bluestone, J.A.3
Miller, S.D.4
-
121
-
-
0030966217
-
Induction of peripheral T cell tolerance in vivo requires CTLA-4 engagement
-
Perez, V. L., L. Van Parijs, A. Biuckians, X. X. Zheng, T. B. Strom & A. K. Abbas: Induction of peripheral T cell tolerance in vivo requires CTLA-4 engagement. Immunity, 6, 411-7 (1997) (Pubitemid 27208196)
-
(1997)
Immunity
, vol.6
, Issue.4
, pp. 411-417
-
-
Perez, V.L.1
Van Parijs, L.2
Biuckians, A.3
Zheng, X.X.4
Strom, T.B.5
Abbas, A.K.6
-
122
-
-
2642655282
-
Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) regulates the unfolding of autoimmune diabetes
-
DOI 10.1084/jem.187.3.427
-
Luhder, F., P. Hoglund, J. P. Allison, C. Benoist & D. Mathis: Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) regulates the unfolding of autoimmune diabetes. J Exp Med, 187, 427-32 (1998) (Pubitemid 28080071)
-
(1998)
Journal of Experimental Medicine
, vol.187
, Issue.3
, pp. 427-432
-
-
Luhder, F.1
Hoglund, P.2
Allison, J.P.3
Benoist, C.4
Mathis, D.5
-
123
-
-
0032490620
-
Cytotoxic T lymphocyte antigen 4 (CTLA4) blockade accelerates the acute rejection of cardiac allografts in CD28-deficient mice: CTLA4 can function independently of CD28
-
DOI 10.1084/jem.188.1.199
-
Lin, H., J. C. Rathmell, G. S. Gray, C. B. Thompson, J. M. Leiden & M. L. Alegre: Cytotoxic T lymphocyte antigen 4 (CTLA4) blockade accelerates the acute rejection of cardiac allografts in CD28-deficient mice: CTLA4 can function independently of CD28. J Exp Med, 188, 199-204 (1998) (Pubitemid 28328618)
-
(1998)
Journal of Experimental Medicine
, vol.188
, Issue.1
, pp. 199-204
-
-
Lin, H.1
Rathmell, J.C.2
Gray, G.S.3
Thompson, C.B.4
Leiden, J.M.5
Alegre, M.-L.6
-
124
-
-
0030872154
-
Protective immunity to nematode infection is induced by CTLA-4 blockade
-
DOI 10.1084/jem.186.2.183
-
McCoy, K., M. Camberis & G. L. Gros: Protective immunity to nematode infection is induced by CTLA-4 blockade. J Exp Med, 186, 183-7 (1997) (Pubitemid 27328018)
-
(1997)
Journal of Experimental Medicine
, vol.186
, Issue.2
, pp. 183-187
-
-
McCoy, K.1
Camberis, M.2
Le Gros, G.3
-
125
-
-
0029947568
-
Enhancement of antitumor immunity by CTLA-4 blockade
-
Leach, D. R., M. F. Krummel & J. P. Allison: Enhancement of antitumor immunity by CTLA-4 blockade. Science, 271, 1734-6 (1996) (Pubitemid 26102823)
-
(1996)
Science
, vol.271
, Issue.5256
, pp. 1734-1736
-
-
Leach, D.R.1
Krummel, M.F.2
Allison, J.P.3
-
126
-
-
0029789389
-
CTLA-4: A negative regulator of autoimmune disease
-
Karandikar, N. J., C. L. Vanderlugt, T. L. Walunas, S. D. Miller & J. A. Bluestone: CTLA-4: a negative regulator of autoimmune disease. J Exp Med, 184, 783-8 (1996) (Pubitemid 26324135)
-
(1996)
Journal of Experimental Medicine
, vol.184
, Issue.2
, pp. 783-788
-
-
Karandikar, N.J.1
Vanderlugt, C.L.2
Walunas, T.L.3
Miller, S.D.4
Bluestone, J.A.5
-
127
-
-
10744233636
-
Blockade of T cell activation using a surface-linked single-chain antibody to CTLA-4 (CD152)
-
Griffin, M. D., D. K. Hong, P. O. Holman, K. M. Lee, M. J. Whitters, S. M. O'Herrin, F. Fallarino, M. Collins, D. M. Segal, T. F. Gajewski, D. M. Kranz & J. A. Bluestone: Blockade of T cell activation using a surface-linked singlechain antibody to CTLA-4 (CD152). J Immunol, 164, 4433-42 (2000) (Pubitemid 30238037)
-
(2000)
Journal of Immunology
, vol.164
, Issue.9
, pp. 4433-4442
-
-
Griffin, M.D.1
Hong, D.K.2
Holman, P.O.3
Lee, K.-M.4
Whitters, M.J.5
O'Herrin, S.M.6
Fallarino, F.7
Collins, M.8
Segal, D.M.9
Gajewski, T.F.10
Kranz, D.M.11
Bluestone, J.A.12
-
128
-
-
33746748176
-
Inhibition of T cell activation and autoimmune diabetes using a B cell surface-linked CTLA-4 agonist
-
DOI 10.1172/JCI27856
-
Fife, B. T., M. D. Griffin, A. K. Abbas, R. M. Locksley & J. A. Bluestone: Inhibition of T cell activation and autoimmune diabetes using a B cell surface-linked CTLA-4 agonist. J Clin Invest, 116, 2252-61 (2006) (Pubitemid 44162335)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.8
, pp. 2252-2261
-
-
Fife, B.T.1
Griffin, M.D.2
Abbas, A.K.3
Locksley, R.M.4
Bluestone, J.A.5
-
129
-
-
0036888591
-
TNF ligands and receptors in autoimmunity: An update
-
DOI 10.1016/S0952-7915(02)00407-7
-
Mackay, F. & S. L. Kalled: TNF ligands and receptors in autoimmunity: an update. Curr Opin Immunol, 14, 783-90 (2002) (Pubitemid 35292427)
-
(2002)
Current Opinion in Immunology
, vol.14
, Issue.6
, pp. 783-790
-
-
Mackay, F.1
Kalled, S.L.2
-
130
-
-
1942475188
-
Autoimmune diabetes in the NOD nouse: An essential role of Fas-FasL signaling in β cell apoptosis
-
DOI 10.1196/annals.1288.018
-
Silva, D. G., L. Socha, B. Charlton, W. Cowden & N. Petrovsky: Autoimmune diabetes in the NOD mouse: an essential role of Fas-FasL signaling in beta cell apoptosis. Ann N Y Acad Sci, 1005, 161-5 (2003) (Pubitemid 38507745)
-
(2003)
Annals of the New York Academy of Sciences
, vol.1005
, pp. 161-165
-
-
Silva, D.G.1
Socha, L.2
Charlton, B.3
Cowden, W.4
Petrovsky, N.5
-
131
-
-
0032932324
-
β-Cell destruction in NOD mice correlates with Fas (CD95) expression on β-cells and proinflammatory cytokine expression in islets
-
DOI 10.2337/diabetes.48.1.21
-
Suarez-Pinzon, W., O. Sorensen, R. C. Bleackley, J. F. Elliott, R. V. Rajotte & A. Rabinovitch: Beta-cell destruction in NOD mice correlates with Fas (CD95) expression on beta-cells and proinflammatory cytokine expression in islets. Diabetes, 48, 21-8 (1999) (Pubitemid 29019348)
-
(1999)
Diabetes
, vol.48
, Issue.1
, pp. 21-28
-
-
Suarez-Pinzon, W.1
Sorensen, O.2
Bleackley, R.C.3
Elliott, J.F.4
Rajotte, R.V.5
Rabinovitch, A.6
-
132
-
-
0030731917
-
Nitric oxide primes pancreatic β cells for Fas-mediated destruction in insulin-dependent diabetes mellitus
-
DOI 10.1084/jem.186.8.1193
-
Stassi, G., R. De Maria, G. Trucco, W. Rudert, R. Testi, A. Galluzzo, C. Giordano & M. Trucco: Nitric oxide primes pancreatic beta cells for Fas-mediated destruction in insulin-dependent diabetes mellitus. J Exp Med, 186, 1193-200 (1997) (Pubitemid 27469014)
-
(1997)
Journal of Experimental Medicine
, vol.186
, Issue.8
, pp. 1193-1200
-
-
Stassi, G.1
De Maria, R.2
Trucco, G.3
Rudert, W.4
Testi, R.5
Galluzzo, A.6
Giordano, C.7
Trucco, M.8
-
133
-
-
2442536706
-
Transgenic expression of decoy receptor 3 protects islets from spontaneous and chemical-induced autoimmune destruction in nonobese diabetic mice
-
DOI 10.1084/jem.20031939
-
Sung, H. H., J. H. Juang, Y. C. Lin, C. H. Kuo, J. T. Hung, A. Chen, D. M. Chang, S. Y. Chang, S. L. Hsieh & H. K. Sytwu: Transgenic expression of decoy receptor 3 protects islets from spontaneous and chemical-induced autoimmune destruction in nonobese diabetic mice. J Exp Med, 199, 1143-51 (2004) (Pubitemid 38619910)
-
(2004)
Journal of Experimental Medicine
, vol.199
, Issue.8
, pp. 1143-1151
-
-
Sung, H.-H.1
Juang, J.-H.2
Lin, Y.-C.3
Kuo, C.-H.4
Hung, J.-T.5
Chen, A.6
Chang, D.-M.7
Chang, S.-Y.8
Hsieh, S.-L.9
Sytwu, H.-K.10
-
134
-
-
17444424930
-
Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer
-
DOI 10.1038/25387
-
Pitti, R. M., S. A. Marsters, D. A. Lawrence, M. Roy, F. C. Kischkel, P. Dowd, A. Huang, C. J. Donahue, S. W. Sherwood, D. T. Baldwin, P. J. Godowski, W. I. Wood, A. L. Gurney, K. J. Hillan, R. L. Cohen, A. D. Goddard, D. Botstein & A. Ashkenazi: Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer. Nature, 396, 699-703 (1998) (Pubitemid 29003951)
-
(1998)
Nature
, vol.396
, Issue.6712
, pp. 699-703
-
-
Pitti, R.M.1
Marsters, S.A.2
Lawrence, D.A.3
Roy, M.4
Kischkel, F.C.5
Dowd, P.6
Huang, A.7
Donahue, C.J.8
Sherwood, S.W.9
Baldwin, D.T.10
Godowski, P.J.11
Wood, W.I.12
Gurney, A.L.13
Hillan, K.J.14
Cohen, R.L.15
Goddard, A.D.16
Botstein, D.17
Ashkenazi, A.18
-
135
-
-
0033553489
-
A newly identified member of tumor necrosis factor receptor superfamily (TR6) suppresses LIGHT-mediated apoptosis
-
Yu, K. Y., B. Kwon, J. Ni, Y. Zhai, R. Ebner & B. S. Kwon: A newly identified member of tumor necrosis factor receptor superfamily (TR6) suppresses LIGHT-mediated apoptosis. J Biol Chem, 274, 13733-6 (1999)
-
(1999)
J Biol Chem
, vol.274
, pp. 13733-13736
-
-
Yu, K.Y.1
Kwon, B.2
Ni, J.3
Zhai, Y.4
Ebner, R.5
Kwon, B.S.6
-
136
-
-
18344385475
-
TL1A is a TNF-like ligand for DR3 and TR6/DcR3 and functions as a T cell costimulator
-
DOI 10.1016/S1074-7613(02)00283-2
-
Migone, T. S., J. Zhang, X. Luo, L. Zhuang, C. Chen, B. Hu, J. S. Hong, J. W. Perry, S. F. Chen, J. X. Zhou, Y. H. Cho, S. Ullrich, P. Kanakaraj, J. Carrell, E. Boyd, H. S. Olsen, G. Hu, L. Pukac, D. Liu, J. Ni, S. Kim, R. Gentz, P. Feng, P. A. Moore, S. M. Ruben & P. Wei: TL1A is a TNF-like ligand for DR3 and TR6/DcR3 and functions as a T cell costimulator. Immunity, 16, 479-92 (2002) (Pubitemid 34260924)
-
(2002)
Immunity
, vol.16
, Issue.3
, pp. 479-492
-
-
Migone, T.-S.1
Zhang, J.2
Luo, X.3
Zhuang, L.4
Chen, C.5
Hu, B.6
Hong, J.S.7
Perry, J.W.8
Chen, S.-F.9
Zhou, J.X.H.10
Cho, Y.H.11
Ullrich, S.12
Kanakaraj, P.13
Carrell, J.14
Boyd, E.15
Olsen, H.S.16
Hu, G.17
Pukac, L.18
Liu, D.19
Ni, J.20
Kim, S.21
Gentz, R.22
Feng, P.23
Moore, P.A.24
Ruben, S.M.25
Wei, P.26
more..
-
137
-
-
0037457891
-
Contribution of Fas to diabetes development
-
DOI 10.1073/pnas.0237359100
-
Savinov, A. Y., A. Tcherepanov, E. A. Green, R. A. Flavell & A. V. Chervonsky: Contribution of Fas to diabetes development. Proc Natl Acad Sci U S A, 100, 628-32 (2003) (Pubitemid 36126103)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.2
, pp. 628-632
-
-
Savinov, A.Y.1
Tcherepanov, A.2
Green, E.A.3
Flavell, R.A.4
Chervonsky, A.V.5
-
138
-
-
0035660806
-
The regulation of T cell homeostasis and autoimmunity by T cell-derived LIGHT
-
DOI 10.1172/JCI200113827
-
Wang, J., J. C. Lo, A. Foster, P. Yu, H. M. Chen, Y. Wang, K. Tamada, L. Chen & Y. X. Fu: The regulation of T cell homeostasis and autoimmunity by T cell-derived LIGHT. J Clin Invest, 108, 1771-80 (2001) (Pubitemid 34015122)
-
(2001)
Journal of Clinical Investigation
, vol.108
, Issue.12
, pp. 1771-1780
-
-
Wang, J.1
Lo, J.C.2
Foster, A.3
Yu, P.4
Chen, H.M.5
Wang, Y.6
Tamada, K.7
Chen, L.8
Fu, Y.-X.9
-
139
-
-
0031567896
-
- T Lymphocytes by 4-1BB Ligand
-
DeBenedette, M. A., A. Shahinian, T. W. Mak & T. H. Watts: Costimulation of CD28- T lymphocytes by 4-1BB ligand. J Immunol, 158, 551-9 (1997) (Pubitemid 127492629)
-
(1997)
Journal of Immunology
, vol.158
, Issue.2
, pp. 551-559
-
-
DeBenedette, M.A.1
Shahinian, A.2
Mak, T.W.3
Watts, T.H.4
-
140
-
-
0033571176
-
Anti-4-1BB monoclonal antibodies abrogate T cell-dependent humoral immune responses in vivo through the induction of helper T cell anergy
-
Mittler, R. S., T. S. Bailey, K. Klussman, M. D. Trailsmith & M. K. Hoffmann: Anti-4-1BB monoclonal antibodies abrogate T cell-dependent humoral immune responses in vivo through the induction of helper T cell anergy. J Exp Med, 190, 1535-40 (1999)
-
(1999)
J Exp Med
, vol.190
, pp. 1535-1540
-
-
Mittler, R.S.1
Bailey, T.S.2
Klussman, K.3
Trailsmith, M.D.4
Hoffmann, M.K.5
-
141
-
-
0036467421
-
Administration of agonistic anti-4-1BB monoclonal antibody leads to the amelioration of experimental autoimmune encephalomyelitis
-
Sun, Y., X. Lin, H. M. Chen, Q. Wu, S. K. Subudhi, L. Chen & Y. X. Fu: Administration of agonistic anti-4- 1BB monoclonal antibody leads to the amelioration of experimental autoimmune encephalomyelitis. J Immunol, 168, 1457-65 (2002) (Pubitemid 34094519)
-
(2002)
Journal of Immunology
, vol.168
, Issue.3
, pp. 1457-1465
-
-
Sun, Y.1
Lin, X.2
Chen, H.M.3
Wu, Q.4
Subudhi, S.K.5
Chen, L.6
Fu, Y.-X.7
-
142
-
-
10744220063
-
Anti-4-1BB-based immunotherapy for autoimmune diabetes: Lessons from a transgenic non-obese diabetic (NOD) model
-
DOI 10.1016/S0896-8411(03)00112-4
-
Sytwu, H. K., W. D. Lin, S. R. Roffler, J. T. Hung, H. S. Sung, C. H. Wang, T. L. Cheng, S. C. Tsou, S. C. Hsi & K. L. Shen: Anti-4-1BB-based immunotherapy for autoimmune diabetes: lessons from a transgenic non-obese diabetic (NOD) model. J Autoimmun, 21, 247-54 (2003) (Pubitemid 37410112)
-
(2003)
Journal of Autoimmunity
, vol.21
, Issue.3
, pp. 247-254
-
-
Sytwu, H.-K.1
Lin, W.-D.2
Roffler, S.R.3
Hung, J.-T.4
Sung, H.-S.5
Wang, C.-H.6
Cheng, T.-L.7
Tsou, S.-C.8
Hsi, S.-C.9
Shen, K.-L.10
-
143
-
-
33749070784
-
International trial of the Edmonton protocol for islet transplantation
-
DOI 10.1056/NEJMoa061267
-
Shapiro, A. M., C. Ricordi, B. J. Hering, H. Auchincloss, R. Lindblad, R. P. Robertson, A. Secchi, M. D. Brendel, T. Berney, D. C. Brennan, E. Cagliero, R. Alejandro, E. A. Ryan, B. DiMercurio, P. Morel, K. S. Polonsky, J. A. Reems, R. G. Bretzel, F. Bertuzzi, T. Froud, R. Kandaswamy, D. E. Sutherland, G. Eisenbarth, M. Segal, J. Preiksaitis, G. S. Korbutt, F. B. Barton, L. Viviano, V. Seyfert-Margolis, J. Bluestone & J. R. Lakey: International trial of the Edmonton protocol for islettransplantation. N Engl J Med, 355, 1318-30 (2006) (Pubitemid 44465460)
-
(2006)
New England Journal of Medicine
, vol.355
, Issue.13
, pp. 1318-1330
-
-
Shapiro, A.M.J.1
Ricordi, C.2
Hering, B.J.3
Auchincloss, H.4
Lindblad, R.5
Robertson, R.P.6
Secchi, A.7
Brendel, M.D.8
Berney, T.9
Brennan, D.C.10
Cagliero, E.11
Alejandro, R.12
Ryan, E.A.13
DiMercurio, B.14
Morel, P.15
Polonsky, K.S.16
Reems, J.-A.17
Bretzel, R.G.18
Bertuzzi, F.19
Froud, T.20
Kandaswamy, R.21
Sutherland, D.E.R.22
Eisenbarth, G.23
Segal, M.24
Preiksaitis, J.25
Korbutt, G.S.26
Barton, F.B.27
Viviano, L.28
Seyfert-Margolis, V.29
Bluestone, J.30
Lakey, J.R.T.31
more..
-
144
-
-
21344462346
-
Five-year follow-up after clinical islet transplantation
-
DOI 10.2337/diabetes.54.7.2060
-
Ryan, E. A., B. W. Paty, P. A. Senior, D. Bigam, E. Alfadhli, N. M. Kneteman, J. R. Lakey & A. M. Shapiro: Five-year follow-up after clinical islet transplantation. Diabetes, 54, 2060-9 (2005) (Pubitemid 40911269)
-
(2005)
Diabetes
, vol.54
, Issue.7
, pp. 2060-2069
-
-
Ryan, E.A.1
Paty, B.W.2
Senior, P.A.3
Bigam, D.4
Alfadhli, E.5
Kneteman, N.M.6
Lakey, J.R.T.7
Shapiro, A.M.J.8
-
145
-
-
0036097472
-
β-cell death and mass in syngeneically transplanted islets exposed to short- and long-term hyperglycemia
-
Biarnes, M., M. Montolio, V. Nacher, M. Raurell, J. Soler & E. Montanya: Beta-cell death and mass in syngeneically transplanted islets exposed to short- and long-term hyperglycemia. Diabetes, 51, 66-72 (2002) (Pubitemid 34517981)
-
(2002)
Diabetes
, vol.51
, Issue.1
, pp. 66-72
-
-
Biarnes, M.1
Montolio, M.2
Nacher, V.3
Raurell, M.4
Soler, J.5
Montanya, E.6
-
146
-
-
0028963533
-
A selective decrease in the beta cell mass of human islets transplanted into diabetic nude mice
-
Davalli, A. M., Y. Ogawa, C. Ricordi, D. W. Scharp, S. Bonner-Weir & G. C. Weir: A selective decrease in the beta cell mass of human islets transplanted into diabetic nude mice. Transplantation, 59, 817-20 (1995)
-
(1995)
Transplantation
, vol.59
, pp. 817-820
-
-
Davalli, A.M.1
Ogawa, Y.2
Ricordi, C.3
Scharp, D.W.4
Bonner-Weir, S.5
Weir, G.C.6
-
147
-
-
0036263218
-
Inhibition of thrombin abrogates the instant blood-mediated inflammatory reaction triggered by isolated human islets: Possible application of the thrombin inhibitor Melagatran in clinical islet transplantation
-
Ozmen, L., K. N. Ekdahl, G. Elgue, R. Larsson, O. Korsgren & B. Nilsson: Inhibition of thrombin abrogates the instant blood-mediated inflammatory reaction triggered by isolated human islets: possible application of the thrombin inhibitor melagatran in clinical islet transplantation. Diabetes, 51, 1779-84 (2002) (Pubitemid 34564290)
-
(2002)
Diabetes
, vol.51
, Issue.6
, pp. 1779-1784
-
-
Ozmen, L.1
Ekdahl, K.N.2
Elgue, G.3
Larsson, R.4
Korsgren, O.5
Nilsson, B.6
-
148
-
-
0037153731
-
Production of tissue factor by pancreatic islet cells as a trigger of detrimental thrombotic reactions in clinical islet transplantation
-
DOI 10.1016/S0140-6736(02)12020-4
-
Moberg, L., H. Johansson, A. Lukinius, C. Berne, A. Foss, R. Kallen, O. Ostraat, K. Salmela, A. Tibell, G. Tufveson, G. Elgue, K. Nilsson Ekdahl, O. Korsgren & B. Nilsson: Production of tissue factor by pancreatic islet cells as a trigger of detrimental thrombotic reactions in clinical islet transplantation. Lancet, 360, 2039-45 (2002) (Pubitemid 36026584)
-
(2002)
Lancet
, vol.360
, Issue.9350
, pp. 2039-2045
-
-
Moberg, L.1
Johansson, H.2
Lukinius, A.3
Berne, C.4
Foss, A.5
Kallen, R.6
Ostraat, O.7
Salmela, K.8
Tibell, A.9
Tufveson, G.10
Elgue, G.11
Nilsson Ekdahl, K.12
Korsgren, O.13
Nilsson, B.14
-
149
-
-
0031127357
-
Adenoviral transfection of isolated pancreatic islets: A study of programmed cell death (apoptosis) and islet function
-
DOI 10.1006/jsre.1997.4995
-
Weber, M., S. Deng, T. Kucher, A. Shaked, R. J. Ketchum & K. L. Brayman: Adenoviral transfection of isolated pancreatic islets: a study of programmed cell death (apoptosis) and islet function. J Surg Res, 69, 23-32 (1997) (Pubitemid 27265822)
-
(1997)
Journal of Surgical Research
, vol.69
, Issue.1
, pp. 23-32
-
-
Weber, M.1
Deng, S.2
Kucher, T.3
Shaked, A.4
Ketchum, R.J.5
Brayman, K.L.6
-
150
-
-
0041375553
-
Targeting recombinant adeno-associated virus vectors to enhance gene transfer to pancreatic islets and liver
-
DOI 10.1038/sj.gt.3302046
-
Loiler, S. A., T. J. Conlon, S. Song, Q. Tang, K. H. Warrington, A. Agarwal, M. Kapturczak, C. Li, C. Ricordi, M. A. Atkinson, N. Muzyczka & T. R. Flotte: Targeting recombinant adeno-associated virus vectors to enhance gene transfer to pancreatic islets and liver. Gene Ther, 10, 1551-8 (2003) (Pubitemid 37063260)
-
(2003)
Gene Therapy
, vol.10
, Issue.18
, pp. 1551-1558
-
-
Loiler, S.A.1
Conlon, T.J.2
Song, S.3
Tang, Q.4
Warrington Jr., K.H.5
Agarwal, A.6
Kapturczak, M.7
Li, C.8
Ricordi, C.9
Atkinson, M.A.10
Muzyczka, N.11
Flotte, T.R.12
-
151
-
-
0030819379
-
Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo
-
Zufferey, R., D. Nagy, R. J. Mandel, L. Naldini & D. Trono: Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo. Nat Biotechnol, 15, 871-5 (1997)
-
(1997)
Nat Biotechnol
, vol.15
, pp. 871-875
-
-
Zufferey, R.1
Nagy, D.2
Mandel, R.J.3
Naldini, L.4
Trono, D.5
-
152
-
-
0029993858
-
Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector
-
DOI 10.1073/pnas.93.21.11382
-
Naldini, L., U. Blomer, F. H. Gage, D. Trono & I. M. Verma: Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector. Proc Natl Acad Sci U S A, 93, 11382-8 (1996) (Pubitemid 26347130)
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, Issue.21
, pp. 11382-11388
-
-
Naldini, L.1
Blomer, U.2
Gage, F.H.3
Trono, D.4
Verma, I.M.5
-
153
-
-
0038621437
-
Gene- and cell-based therapeutics for type I diabetes mellitus
-
DOI 10.1038/sj.gt.3302015
-
Bottino, R., P. Lemarchand, M. Trucco & N. Giannoukakis: Gene- and cell-based therapeutics for type I diabetes mellitus. Gene Ther, 10, 875-89 (2003) (Pubitemid 36665298)
-
(2003)
Gene Therapy
, vol.10
, Issue.10
, pp. 875-889
-
-
Bottino, R.1
Lemarchand, P.2
Trucco, M.3
Giannoukakis, N.4
-
154
-
-
0032506750
-
Lentivirus-mediated transduction of islet grafts with interleukin 4 results in sustained gene expression and protection from insulitis
-
Gallichan, W. S., T. Kafri, T. Krahl, I. M. Verma & N. Sarvetnick: Lentivirus-mediated transduction of islet grafts with interleukin 4 results in sustained gene expression and protection from insulitis. Hum Gene Ther, 9, 2717-26 (1998) (Pubitemid 29027015)
-
(1998)
Human Gene Therapy
, vol.9
, Issue.18
, pp. 2717-2726
-
-
Gallichan, W.S.1
Kafri, T.2
Krahl, T.3
Verma, I.M.4
Sarvetnick, N.5
-
155
-
-
0023921176
-
Diabetes in transgenic mice resulting from over-expression of class i histocompatibility molecules in pancreatic beta cells
-
Allison, J., I. L. Campbell, G. Morahan, T. E. Mandel, L. C. Harrison & J. F. Miller: Diabetes in transgenic mice resulting from over-expression of class I histocompatibility molecules in pancreatic beta cells. Nature, 333, 529-33 (1988)
-
(1988)
Nature
, vol.333
, pp. 529-533
-
-
Allison, J.1
Campbell, I.L.2
Morahan, G.3
Mandel, T.E.4
Harrison, L.C.5
Miller, J.F.6
-
156
-
-
0024281396
-
Diabetes and tolerance in transgenic mice expressing class II MHC molecules in pancreatic beta cells
-
Lo, D., L. C. Burkly, G. Widera, C. Cowing, R. A. Flavell, R. D. Palmiter & R. L. Brinster: Diabetes and tolerance in transgenic mice expressing class II MHC molecules in pancreatic beta cells. Cell, 53, 159-68 (1988)
-
(1988)
Cell
, vol.53
, pp. 159-168
-
-
Lo, D.1
Burkly, L.C.2
Widera, G.3
Cowing, C.4
Flavell, R.A.5
Palmiter, R.D.6
Brinster, R.L.7
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