Chemoprevention through the Keap1-Nrf2 signaling pathway by phase 2 enzyme inducers

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 555, Issue 1-2 SPEC. ISS., 2004, Pages 133-148

  Kwak, Mi Kyoung ^a   Wakabayashi, Nobunao ^a   Kensler, Thomas W ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Antioxidant response element; Cancer prevention; Dithiolethiones; Gene regulation; Oxidative stress

Indexed keywords

ANTIINFECTIVE AGENT; DITHIOL DERIVATIVE; GLUTATHIONE TRANSFERASE; KEAP1 PROTEIN; OLTIPRAZ; PROTEIN; PROTEIN DERIVATIVE; THIOKETONE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NF E2; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

CANCER CHEMOTHERAPY; CANCER PREVENTION; CARCINOGENESIS; CELL INTERACTION; COMPLEX FORMATION; DIMERIZATION; DNA FLANKING REGION; DRUG EFFICACY; DRUG POTENCY; ENZYME INDUCTION; ENZYME METABOLISM; GENE; GENE DISRUPTION; GENE EXPRESSION; GENE INDUCTION; GENETIC CONSERVATION; GENETIC SCREENING; GENETIC SUSCEPTIBILITY; HUMAN; KEAP1 GENE; MOLECULAR INTERACTION; NONHUMAN; NRF 2 GENE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN STABILITY; REVIEW; SCREENING TEST; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANTICARCINOGENIC AGENTS; CHEMOPREVENTION; CYTOSKELETAL PROTEINS; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; GLUTATHIONE TRANSFERASE; HUMANS; NEOPLASMS; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS;

ANIMALIA; MAMMALIA;

EID: 5144232811     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2004.06.041     Document Type: Review

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