Isolation of cDNAs representing dithiolethione-responsive genes

Carcinogenesis

Volumn 17, Issue 11, 1996, Pages 2297-2303

  Primiano, Thomas ^a   Gastel, Jonathan A ^a   Kensler, Thomas W ^a   Sutter, Thomas R ^a  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,2 DITHIOLE 3 THIONE DERIVATIVE; AFLATOXIN B1; ALDEHYDE REDUCTASE; ANTINEOPLASTIC AGENT; COMPLEMENTARY DNA; EPOXIDE HYDROLASE; GLUTATHIONE TRANSFERASE; MESSENGER RNA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE);

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DETOXIFICATION; DNA LIBRARY; DRUG DNA INTERACTION; GENE INDUCTION; GENE ISOLATION; LIVER; MALE; MOLECULAR CLONING; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT; TRANSCRIPTION REGULATION;

EID: 0029803486     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/17.11.2297     Document Type: Article

References (50)

1. Wattenberg, L.W. (1985) Chemoprevention of cancer. Cancer Res., 45, 1-8.
2. Kensler, T.W., Groopman, J.D., Roebuck, B.D. and Curphey, T.J. (1994) Chemoprotection by 1,2-dithiole-3-thiones. In Huang, M.-T., Osawa, T., Ho, C.-T. and Rosen, R.T. (eds), Food Phytochemicals for Cancer Prevention I: Fruits and Vegetables. American Chemical Society, Washington, DC, pp. 154-163.
3. Wattenberg, L.W. and Bueding, E. (1986) Inhibitory effects of 5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione (oltipraz) on carcinogenesis induced by benzo[o]pyrene, diethylnitrosamine and uracil mustard. Carcinogenesis, 7, 1379-1388.
4. Kensler, T.W., Egner, P.A., Dolan, P., Groopman, J.D. and Roebuck, B.D. (1987) Mechanism of protection against aflatoxin tumorigenicity in rats fed 5-(2-pyrazinyl)-4-methy 1-1,2-dithiol-3-thione (oltipraz) and related 1,2-dithiol-3-thiones and 1,2-dithiol-3-ones. Cancer Res., 47, 4271-4277.
5. Kensler, T.W. and Helzlsouer, K.J. (1995) Oltipraz: clinical opportunities for cancer chemoprevention. J. Cell. Biochem., 22S, 101-107.
6. DeLong, M.J., Dolan, P., Santamaria, A.B. and Bueding, E. (1986) 1,2-Dithiol-3-thione analogs: effects on NAD(P)H:quinone reductase and glutathione levels in murine hepatoma cells. Carcinogenesis, 7, 977-980.
7. Prochaska, H. and Talalay, P. (1988) Regulatory mechanisms of monofunctional and bifunctional anticarcinogenic enzyme inducers in murine liver. Cancer Res., 48, 4776-4782.
8. Kensler, T.W., Groopman, J.D., Eaton, D.L., Curphey, T.J. and Roebuck, B.D. (1992) Potent inhibition of aflatoxin-induced hepatic tumorigenesis by the monofunctional enzyme inducer 1,2-dithiol-3-thione. Carcinogenesis, 13, 95-100.
9. Daniel, V., Sharon, R., Tichauer, Y. and Sarid, S. (1986) Mouse glutathione S-transferase Ya subunit: gene structure and sequence. DNA, 6, 317-324.
10. Davidson, N.E., Egner, P.A. and Kensler, T.W. (1990) Transcriptional control of glutathione S-transferase gene expression by the chemoprotective agent 5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione (oltipraz) in rat liver. Cancer Res., 50, 2251-2257.
11. Jaiswal, A. (1994) Antioxidant response element. Biochem. Pharmacol., 48, 439-444.
12. Mackenzie, P. and Rodbourn, L. (1990) Organization of the rat UDP-glucuronosyltransferase, UDPGTr-2, gene and characterization of its promoter. J. Biol. Chem., 265, 11328-11332.
13. Bell, P., Falany, C.N., McQuiddy, P. and Kasper, C.B. (1990) Glucocorticoid repression and basal regulation of the epoxide hydrolase promoter. Arch. Bochem. Biophys., 279, 363-369.
14. Prestera, T., Holtzclaw, W.D., Zhang, Y. and Talalay, P. (1993) Chemical and molecular regulation of enzymes that detoxify carcinogens. Proc. Natl Acad. Sci. USA, 90, 2965-2969.
15. Egner, P.A., Kensler, T.W., Prestera, T., Talalay, P., Libby, A.H., Joyner, H.H. and Curphey, T.J. (1994) Regulation of phase 2 enzyme induction by oltipraz and other dithiolethiones. Carcinogenesis, 15, 177-181.
16. Sharma, S., Stutzman, J.D., Keloff, G.J. and Steele, V.E. (1994) Screening of potential chemopreventive agents using biochemical markers of carcinogenesis. Cancer Res., 54, 5848-5855.
17. 1 is associated with the expression of a novel aldo-keto reductase which has catalytic activity towards a cytotoxicity aldehyde-containing metabolite of the toxin. Cancer Res., 53, 3887-3894.
18. Sharma, S. and Stutzman, J. (1993) A study of the candidate chemopreventive agent, oltipraz by gene regulation mapping. Proc. Am. Ass. Cancer Res., 34, 549.
19. Hayes, J.D., Nguyen, T., Judah, D.J., Petersson, D.G. and Neal, G.E. (1994) Cloning of cDNAs from fetal rat liver encoding glutathione S-transferase Yc polypeptides. J. Biol. Chem., 269, 20707-20717.
20. Favreau, L.V. and Pickett, C.B. (1991) Transcriptional regulation of the rat NAD(P)H:quinone reductase gene: identification of regulatory elements controlling basal level expression and inducible expression by planar aromatic compounds and phenolic antioxidants. J. Biol. Chem., 266, 4556-4561.
21. Chomcynski, P. and Sacchi, N. (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem., 162, 156-159.
22. Maniatis, T., Fritsch, E.F. and Sambrook, J. (1989) Molecular cloning: A Laboratory Manual, 2nd Edn. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
23. Sutter, T.R., Guzman, K., Dold, K.M. and Greenlee, W.F. (1991) Targets for dioxin: genes for plasminogen activator inhibitor-2 and interleukin-1β. Science, 254, 415-418.
24. Gastel, J.A. and Sutter, T.R. (1996) A control system for cDNA enrichment reactions. BioTechniques, 20, 870-875.
25. Dunigan, D.D., Smart, T.E. and Zaitlan, M. (1987) A differential color coding aid for colony/plaque screening analysis. BioTechniques, 5, 32-37.
26. Altschul, S.F., Gish, W., Miller, W., Myers, E.W. and Lipman, D.J. (1992) Basic local alignment search tool. J. Mol. Biol., 215, 403-410.
27. Tukey, R.H. and Okino, S.T. (1991) Quantitation of related gene products by nuclear run-on and northern blot analysis. Methods Enzymol., 206, 284-289.
28. Celano, P., Berchtold, C. and Casero, R.A., Jr (1989) A simplification of the nuclear run-off transcription assay. BioTechniques, 7, 942-944.
29. Lai, H.-C.J., Grove, G. and Tu, C.-P.D. (1986) Cloning and sequence analysis of a cDNA for a rat liver glutathione S-transferase Yb subunit. Nucleic Acids Res., 14, 6101-6114.
30. Sugioka, Y., Kano, T., Okuda, A., Sakai, M., Kitigawa, T. and Muramatsu, M. (1986) Cloning and nucleotide sequence of rat glutathione S-transferase P cDNA. Nucleic Acids Res., 13, 6049-6057.
31. Porter, T.D., Beck, T.W. and Kasper, C.B. (1986) Complementary DNA and amino acid sequence of rat liver microsomal, xenobiotic epoxide hydrolase. Arch. Biochem. Biophys., 248, 121-129.
32. 1 defines a sub-family of aldo-keto reductases. Proc. Natl Acad. Sci. USA, 90, 10350-10354.
33. Leibold, E.A., Aziz, N., Brown, A.J.P. and Munro, H.N. (1984) Conservation in rat liver of light and heavy subunit sequences of mammalian ferritin: presence of unique octapeptide in the light subunit. J. Biol. Chem., 259, 4327-4334.
34. Murray, M., White, K. and Munro, H. (1987) Conservation of ferritin heavy subunit gene structure: implications for the regulation of ferritin gene expression. Proc. Natl Acad. Sci. USA, 84, 7438-7442.
35. Aoyama, Y., Chan, Y.L., Meyuhas, O. and Wool, I.G. (1989) The primary structure of rat ribosomal protein L18a. FEBS Lett., 247, 242-246
36. Chan, Y.L., Paz, V., Olvera, J. and Wool, I.G. (1990) The primary structure of rat ribosomal protein S16. FEBS Lett., 263, 85-88.
37. Boll, W., Schmid-Chanda, T., Semenza, G. and Mantei, N. (1993) Messenger RNAs expressed in intestine of adult but not baby rabbits. J. Biol. Chem., 268, 12901-12911.
38. Liu, X. and Chang, K.-P. (1994) Identification by extrachromosomal amplification and over-expression of zeta-crystallin/NADPH-oxido-reductase homologue constitutively expressed in Leishmania spp. Mol. Biochem. Parasitol., 66, 210-210.
39. Gonzalez, P., Rao, P.V. and Zigler, J.S., Jr (1993) Molecular cloning and sequencing of zeta-crystallin/quinone reductase cDNA from human liver. Biochem. Biophys. Res. Commun., 191, 902-907.
40. Saliola, M., Gonnella, R., Mazzoni, C. and Falcone, C. (1991) Two genes encoding putative mitochondrial alcohol dehydrogenases are present in yeast Kluyveromyces lactis. Yeast, 7, 391-400.
41. Russell, P.R. and Hall, B.J. (1983) The primary sequence of the alcohol dehydrogenase gene from fission yeast Schizosaccharomyces pombe. J. Biol. Chem., 258, 143-149.
42. Eklund, H., Nordstrom, B., Zeppezauer, E., Soderland, G., Ohlsson, I., Bowie, T., Soderberg, B.-O., Tapia, O. and Branden, C.-I. (1976) Three dimensional structure of horse liver alcohol dehydrogenase at 2.4 Å resolution. J. Mol. Biol., 102, 27-59.
43. Rossmann, M., Liljas, A., Branden, C. and Banaszak, L.J. (1975) In Evolutionary and Structural Relationship among Dehydrogenases. Academic Press, New York, NY.
44. Takahira, T., Ochiai, M., Hayashi, K., Nagao, M. and Sugimura, T. (1987) Activation of human c-raf-I by replacing the N-terminal region with different sequences. Nucleic Acids Res., 15, 4809-4820.
45. Davidson, N.E., Egner, P.A. and Kensler, T.W. (1990) Transcriptional control of glutathione S-transferase gene expression by the chemoprotective agent 5-(2-pyrazinyl)-4-methyl-1,2-dithiole-3-thione (oltipraz) in rat liver. Cancer Res., 50, 2251-2257.
46. Munro, H. (1993) The ferritin genes: their response to iron status. Nutr. Rev., 51, 5-19.
47. Theil, E.C. (1990) The ferritin family of iron storage proteins. Adv. Enzymol., 63, 421-449.
48. Primiano, T., Kensler, T.W. and Sutter, T.R. (1996) Induction of hepatic heme oxygenase-1 and ferritin in rats by cancer chemopreventive dithiolethiones. Carcinogenesis, 17, 2291-2296.
49. Cairo, G., Tacchini, L., Pogliaghi, G., Anzon, E., Tomasi, A. and Bernelli-Zazzera, A. (1995) Induction of ferritin synthesis by oxidative stress: transcriptional and post-transcriptional regulation by expansion of the 'free' iron pool. J. Biol. Chem., 270, 700-703.
50. Kensler, T.W., Trush, M.A. and Guyton, K.Z. (1992) Free radicals as targets for cancer protection: prospects and problems. In Steele, V.E., Stoner, G.D., Boone, C.W. and Kelloff, G.J. (eds), Cellular and Molecular Targets for Chemoprevention. CRC Press, Boca Raton, FL, pp. 173-192.