NADPH oxidase activity is essential for Keap1/Nrf2-mediated induction of GCLC in response to 2-indol-3-yl-methylenequinuclidin-3-ols

Cancer Research

Volumn 63, Issue 17, 2003, Pages 5636-5645

  Sekhar, Konjeti R ^a   Crooks, Peter A ^b   Sonar, Vijayakumar N ^b   Friedman, David B ^a   Chan, Jeff Y ^c   Meredith, Michael J ^d   Starnes, Joseph H ^a   Kelton, Kathy R ^a   Summar, Samantha R ^a   Sasi, Soumya ^a   Freeman, Michael L ^a,e  

^a VANDERBILT INGRAM CANCER CENTER   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^e VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 INDOL 3 YLMETHYLENEQUINUCLIDIN 3 OL; DIPHENYLIODONIUM SALT; GLUTAMATE CYSTEINE LIGASE; INDOLE DERIVATIVE; INDOMETACIN; MESSENGER RNA; NUCLEAR FACTOR ERYTHROID 2P45 RELATED TRANSCRIPTION FACTOR; PROTEIN KEAP1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; VJ 111; VJ 112; VJ 112 OH; VJ 113; VJ 114; VJ 115; VJ 142; VJ 145; VJ 147; VJ 175;

AMINO ACID SYNTHESIS; ARTICLE; CHEMOPROPHYLAXIS; CONTROLLED STUDY; DRUG RESPONSE; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME MECHANISM; GCLC GENE; GCLM GENE; GENE; GENE FUNCTION; GENE INDUCTION; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; OXIDATION; PRIORITY JOURNAL; REDUCTION; STRUCTURE ANALYSIS;

ANIMALS; ANTICARCINOGENIC AGENTS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUTAMATE-CYSTEINE LIGASE; HUMANS; INDOLES; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; NADPH OXIDASE; PROTEINS; QUINUCLIDINES; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 0141481195     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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