Decreased levels of proteasome activity and proteasome expression in aging spinal cord

Neuroscience

Volumn 98, Issue 1, 2000, Pages 149-156

  Keller, J N ^a   Huang, F F ^a   Markesbery, W R ^a,b  

^a UNIVERSITY OF KENTUCKY   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

Author keywords

4 Hydroxynonenal; Aging; Motor neuron; Oxidative stress; Proteasome; Spinal cord

Indexed keywords

4 HYDROXYNONENAL; ALDEHYDE; ANTIOXIDANT; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE INHIBITOR; FERROUS SULFATE; GLUTATHIONE; LACTACYSTIN; PROTEASOME; PROTEINASE INHIBITOR;

AGE; AGING; ANIMAL CELL; ARTICLE; CELL DEATH; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; FEMALE; GENE EXPRESSION; IMMUNOPRECIPITATION; LIPID PEROXIDATION; MOTONEURON; NERVE CELL CULTURE; NERVE CELL DEGENERATION; NERVE CELL NECROSIS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; SPINAL CORD; WESTERN BLOTTING;

ACETYLCYSTEINE; AGING; ALDEHYDES; AMINO ACID CHLOROMETHYL KETONES; ANIMALS; CELL DEATH; CELL SURVIVAL; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; GLUTATHIONE; IRON; LIPID PEROXIDATION; LYSOSOMES; MICE; MOTOR NEURONS; MULTIENZYME COMPLEXES; NEUROBLASTOMA; OLIGOPEPTIDES; OXIDATIVE STRESS; PROTEASOME ENDOPEPTIDASE COMPLEX; RATS; RATS, INBRED F344; REACTIVE OXYGEN SPECIES; SPINAL CORD; TUMOR CELLS, CULTURED;

EID: 0034087369     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(00)00067-1     Document Type: Article

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