-
1
-
-
2342481172
-
Programmed cell deaths: Apop-tosis and alternative deathstyles
-
Assuncao Guimaraes C, Linden R. Programmed cell deaths: apop-tosis and alternative deathstyles. Eur J Biochem 2004;271:1638-50.
-
(2004)
Eur J Biochem
, vol.271
, pp. 1638-1650
-
-
Assuncao Guimaraes, C.1
Linden, R.2
-
2
-
-
33745365931
-
Proteolytic and lipolytic responses to starvation
-
Finn PF, Dice JF Proteolytic and lipolytic responses to starvation. Nutrition 2006;22:830-44.
-
(2006)
Nutrition
, vol.22
, pp. 830-844
-
-
Finn, P.F.1
Dice, J.F.2
-
3
-
-
0028797005
-
Degradation of proteasomes by lysosomes in rat liver
-
Cuervo AM, Palmer A, Rivett AJ, et al. Degradation of proteasomes by lysosomes in rat liver. Eur J Biochem 1995;227:792-800.
-
(1995)
Eur J Biochem
, vol.227
, pp. 792-800
-
-
Cuervo, A.M.1
Palmer, A.2
Rivett, A.J.3
-
4
-
-
34548299555
-
Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability
-
Ding WX, Ni HM, Gao W, et al. Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability. Am J Pathol 2007; 171:513-24.
-
(2007)
Am J Pathol
, vol.171
, pp. 513-524
-
-
Ding, W.X.1
Ni, H.M.2
Gao, W.3
-
5
-
-
1842583789
-
Development by self-digestion: Molecular mechanisms and biological functions of autophagy
-
Levine B, Klionsky DJ. Development by self-digestion: molecular mechanisms and biological functions of autophagy. Dev Cell 2004;6:463-77.
-
(2004)
Dev Cell
, vol.6
, pp. 463-477
-
-
Levine, B.1
Klionsky, D.J.2
-
6
-
-
33750974189
-
Endoplasmic reticulum and Golgi complex: Contributions to, and turnover by, autophagy
-
Mijaljica D, Prescott M, Devenish RJ. Endoplasmic reticulum and Golgi complex: contributions to, and turnover by, autophagy. Traffic 2006;7:1590-5.
-
(2006)
Traffic
, vol.7
, pp. 1590-1595
-
-
Mijaljica, D.1
Prescott, M.2
Devenish, R.J.3
-
7
-
-
34548188741
-
Self-eating and self-killing: Crosstalk between autophagy and apoptosis
-
Maiuri MC, Zalckvar E, Kimchi A, et al. Self-eating and self-killing: crosstalk between autophagy and apoptosis. Nat Rev Mol Cell Biol 2007;8:741-52.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 741-752
-
-
Maiuri, M.C.1
Zalckvar, E.2
Kimchi, A.3
-
8
-
-
34249978518
-
Autophagy and NF-kappaB: Fight for fate
-
Xiao G. Autophagy and NF-kappaB: fight for fate. Cytokine Growth Factor Rev 2007;18:233-43.
-
(2007)
Cytokine Growth Factor Rev
, vol.18
, pp. 233-243
-
-
Xiao, G.1
-
9
-
-
0026059280
-
Membrane markers of endoplasmic reticulum preserved in autophagic vacuolar membranes isolated from leupeptin-administered rat liver
-
Ueno T, Muno D, Kominami E. Membrane markers of endoplasmic reticulum preserved in autophagic vacuolar membranes isolated from leupeptin-administered rat liver. J Biol Chem 1991;266:18995-9.
-
(1991)
J Biol Chem
, vol.266
, pp. 18995-18999
-
-
Ueno, T.1
Muno, D.2
Kominami, E.3
-
10
-
-
0025363276
-
Studies on the mechanisms of autophagy: Formation of the autophagic vacuole
-
Dunn WA Jr. Studies on the mechanisms of autophagy: formation of the autophagic vacuole. J Cell Biol 1990;110:1923-33.
-
(1990)
J Cell Biol
, vol.110
, pp. 1923-1933
-
-
Dunn Jr., W.A.1
-
11
-
-
10744225487
-
A unified nomenclature for yeast autophagy-related genes
-
Klionsky DJ, Cregg JM, Dunn WA Jr, et al. A unified nomenclature for yeast autophagy-related genes. Dev Cell 2003;5:539-45.
-
(2003)
Dev Cell
, vol.5
, pp. 539-545
-
-
Klionsky, D.J.1
Cregg, J.M.2
Dunn Jr, W.A.3
-
12
-
-
9144224360
-
Human light chain 3/MAP1LC3B is cleaved at its carboxyl-terminal Met 121 to expose Gly 120 for lipidation and targeting to autophagosomal membranes
-
Tanida I, Ueno T, Kominami E. Human light chain 3/MAP1LC3B is cleaved at its carboxyl-terminal Met 121 to expose Gly 120 for lipidation and targeting to autophagosomal membranes. J Biol Chem 2004;279:47704-10.
-
(2004)
J Biol Chem
, vol.279
, pp. 47704-47710
-
-
Tanida, I.1
Ueno, T.2
Kominami, E.3
-
13
-
-
0034329418
-
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
-
Kabeya Y, Mizushima N, Ueno T, et al. LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. Embo J 2000;19:5720-8.
-
(2000)
Embo J
, vol.19
, pp. 5720-5728
-
-
Kabeya, Y.1
Mizushima, N.2
Ueno, T.3
-
14
-
-
0034707036
-
A ubiquitin-like system mediates protein lipidation
-
Ichimura Y, Kirisako T, Takao T, et al. A ubiquitin-like system mediates protein lipidation. Nature 2000;408:488-92.
-
(2000)
Nature
, vol.408
, pp. 488-492
-
-
Ichimura, Y.1
Kirisako, T.2
Takao, T.3
-
15
-
-
0035911162
-
Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells
-
Mizushima N, Yamamoto A, Hatano M, et al. Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells. J Cell Biol 2001;152:657-68.
-
(2001)
J Cell Biol
, vol.152
, pp. 657-668
-
-
Mizushima, N.1
Yamamoto, A.2
Hatano, M.3
-
16
-
-
0035910423
-
The human homolog of Saccharomyces cerevisiae Apg7p is a protein-activating enzyme for multiple substrates including human Apgl2p, GATE-16, GA-BARAP, and MAP-LC3
-
Tanida I, Tanida-Miyake E, Ueno T, et al. The human homolog of Saccharomyces cerevisiae Apg7p is a protein-activating enzyme for multiple substrates including human Apgl2p, GATE-16, GA-BARAP, and MAP-LC3. J Biol Chem 2001;276:1701-6.
-
(2001)
J Biol Chem
, vol.276
, pp. 1701-1706
-
-
Tanida, I.1
Tanida-Miyake, E.2
Ueno, T.3
-
17
-
-
33745088813
-
Structure-function relationship of Atgl2, a ubiquitin-like modifier essential for autophagy
-
Hanada T, Ohsumi Y Structure-function relationship of Atgl2, a ubiquitin-like modifier essential for autophagy. Autophagy 2005; 1: 110-8.
-
(2005)
Autophagy
, vol.1
, pp. 110-118
-
-
Hanada, T.1
Ohsumi, Y.2
-
18
-
-
0033565655
-
Apgl6p is required for the function of the Apg 12p-Apg5p conjugate in the yeast autophagy pathway
-
Mizushima N, Noda T, Ohsumi Y Apgl6p is required for the function of the Apg 12p-Apg5p conjugate in the yeast autophagy pathway. Embo J 1999;18:3888-96.
-
(1999)
Embo J
, vol.18
, pp. 3888-3896
-
-
Mizushima, N.1
Noda, T.2
Ohsumi, Y.3
-
19
-
-
0037166241
-
Formation of the approximately 350-kDa Apgl2-Apg5.Apgl6 multimeric complex, mediated by Apgl6 oligomerization, is essential for autophagy in yeast
-
Kuma A, Mizushima N, Ishihara N, et al. Formation of the approximately 350-kDa Apgl2-Apg5.Apgl6 multimeric complex, mediated by Apgl6 oligomerization, is essential for autophagy in yeast. J Biol Chem 2002;277:18619-25.
-
(2002)
J Biol Chem
, vol.277
, pp. 18619-18625
-
-
Kuma, A.1
Mizushima, N.2
Ishihara, N.3
-
20
-
-
0034722378
-
Dissection of autophagosome biogenesis into distinct nucleation and expansion steps
-
Abeliovich H, Dunn WA Jr, Kim J, et al. Dissection of autophagosome biogenesis into distinct nucleation and expansion steps. J Cell Biol 2000;151:1025-34.
-
(2000)
J Cell Biol
, vol.151
, pp. 1025-1034
-
-
Abeliovich, H.1
Dunn Jr, W.A.2
Kim, J.3
-
21
-
-
33749570745
-
Enhancing macro-autophagy protects against ischemia/reperfusion injury in cardiac myocytes
-
Hamacher-Brady A, Brady NR, Gottlieb RA. Enhancing macro-autophagy protects against ischemia/reperfusion injury in cardiac myocytes. J Biol Chem 2006;281:29776-87.
-
(2006)
J Biol Chem
, vol.281
, pp. 29776-29787
-
-
Hamacher-Brady, A.1
Brady, N.R.2
Gottlieb, R.A.3
-
22
-
-
19944434059
-
Inhibition of macro-autophagy triggers apoptosis
-
Boya P, Gonzalez-Polo RA, Casares N, et al. Inhibition of macro-autophagy triggers apoptosis. Mol Cell Biol 2005;25:1025-40.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 1025-1040
-
-
Boya, P.1
Gonzalez-Polo, R.A.2
Casares, N.3
-
23
-
-
34247554965
-
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis
-
Rioux JD, Xavier RJ, Taylor KD, et al. Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat Genet 2007; 39:596-604.
-
(2007)
Nat Genet
, vol.39
, pp. 596-604
-
-
Rioux, J.D.1
Xavier, R.J.2
Taylor, K.D.3
-
24
-
-
0033978633
-
Distinct classes of phosphatidylinositol 3'-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells
-
Petiot A, Ogier-Denis E, Blommaart EF, et al. Distinct classes of phosphatidylinositol 3'-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells. J Biol Chem 2000; 275:992-8.
-
(2000)
J Biol Chem
, vol.275
, pp. 992-998
-
-
Petiot, A.1
Ogier-Denis, E.2
Blommaart, E.F.3
-
25
-
-
34047154536
-
ATG1, an autophagy regulator, inhibits cell growth by negatively regulating S6 kinase
-
Lee SB, Kim S, Lee J, et al. ATG1, an autophagy regulator, inhibits cell growth by negatively regulating S6 kinase. EMBO Rep 2007;8:360-5.
-
(2007)
EMBO Rep
, vol.8
, pp. 360-365
-
-
Lee, S.B.1
Kim, S.2
Lee, J.3
-
26
-
-
34548102440
-
-
Neufeld TP Contribution of Atgl-dependent autophagy to TOR-mediated cell growth and survival. Autophagy 2007;3:477-9.
-
Neufeld TP Contribution of Atgl-dependent autophagy to TOR-mediated cell growth and survival. Autophagy 2007;3:477-9.
-
-
-
-
27
-
-
0034644525
-
-
Schmelzle T, Hall MN. TOR, a central controller of cell growth. Cell 2000;103:253-62.
-
Schmelzle T, Hall MN. TOR, a central controller of cell growth. Cell 2000;103:253-62.
-
-
-
-
28
-
-
34548700597
-
Rapamycin: Something old, something new, sometimes borrowed and now renewed
-
Hartford CM, Ratain MJ. Rapamycin: something old, something new, sometimes borrowed and now renewed. Clin Pharmacol Ther 2007;82:381-8.
-
(2007)
Clin Pharmacol Ther
, vol.82
, pp. 381-388
-
-
Hartford, C.M.1
Ratain, M.J.2
-
29
-
-
10944261058
-
Mammalian target of rapamycin (mTOR) inhibitors as anti-cancer agents
-
Rao RD, Buckner JC, Sarkaria JN. Mammalian target of rapamycin (mTOR) inhibitors as anti-cancer agents. Curr Cancer Drug Targets 2004;4:621-35.
-
(2004)
Curr Cancer Drug Targets
, vol.4
, pp. 621-635
-
-
Rao, R.D.1
Buckner, J.C.2
Sarkaria, J.N.3
-
30
-
-
33750072949
-
mTOR and cancer therapy
-
Easton JB, Houghton PJ. mTOR and cancer therapy. Oncogene 2006;25:6436-46.
-
(2006)
Oncogene
, vol.25
, pp. 6436-6446
-
-
Easton, J.B.1
Houghton, P.J.2
-
31
-
-
0034683568
-
Tor-mediated induction of autophagy via an Apgl protein kinase complex
-
Kamada Y, Funakoshi T, Shintani T, et al. Tor-mediated induction of autophagy via an Apgl protein kinase complex. J Cell Biol 2000;150:1507-13.
-
(2000)
J Cell Biol
, vol.150
, pp. 1507-1513
-
-
Kamada, Y.1
Funakoshi, T.2
Shintani, T.3
-
33
-
-
33750366092
-
Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes
-
Young AR, Chan EY, Hu XW, et al. Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes. J Cell Sci 2006;119:3888-900.
-
(2006)
J Cell Sci
, vol.119
, pp. 3888-3900
-
-
Young, A.R.1
Chan, E.Y.2
Hu, X.W.3
-
34
-
-
32244442749
-
Functional specificity of the mammalian Beclin-Vps34 PI 3-kinase complex in macroautophagy versus endocytosis and lysosomal enzyme trafficking
-
Zeng X, Overmeyer JH, Maltese WA. Functional specificity of the mammalian Beclin-Vps34 PI 3-kinase complex in macroautophagy versus endocytosis and lysosomal enzyme trafficking. J Cell Sci 2006;119:259-70.
-
(2006)
J Cell Sci
, vol.119
, pp. 259-270
-
-
Zeng, X.1
Overmeyer, J.H.2
Maltese, W.A.3
-
35
-
-
39049194057
-
The evolutionary conserved domain of Beclin 1 is required for Vps34 binding, autophagy and tumor suppressor function
-
Furuya N, Yu J, Byfield M, et al. The evolutionary conserved domain of Beclin 1 is required for Vps34 binding, autophagy and tumor suppressor function. Autophagy 2005;1:46-52.
-
(2005)
Autophagy
, vol.1
, pp. 46-52
-
-
Furuya, N.1
Yu, J.2
Byfield, M.3
-
36
-
-
34548497874
-
Telomere 3' overhang-specific DNA oligonucleotides induce autophagy in malignant glioma cells
-
Aoki H, Iwado E, Eller MS, et al. Telomere 3' overhang-specific DNA oligonucleotides induce autophagy in malignant glioma cells. Faseb J 2007;21:2918-30.
-
(2007)
Faseb J
, vol.21
, pp. 2918-2930
-
-
Aoki, H.1
Iwado, E.2
Eller, M.S.3
-
37
-
-
34548074436
-
Roles of mTOR and STAT3 in autophagy induced by telomere 3' overhang-specific DNA oligonucleotides
-
Yokoyama T, Kondo Y, Kondo S. Roles of mTOR and STAT3 in autophagy induced by telomere 3' overhang-specific DNA oligonucleotides. Autophagy 2007;3:496-8.
-
(2007)
Autophagy
, vol.3
, pp. 496-498
-
-
Yokoyama, T.1
Kondo, Y.2
Kondo, S.3
-
38
-
-
34547207205
-
Autophagy joins the game to regulate NF-kappaB signaling pathways
-
Djavaheri-Mergny M, Codogno P. Autophagy joins the game to regulate NF-kappaB signaling pathways. CellRes 2007;17:576-7.
-
(2007)
CellRes
, vol.17
, pp. 576-577
-
-
Djavaheri-Mergny, M.1
Codogno, P.2
-
39
-
-
34250886966
-
Hsp90 regulates processing of NF-kappaB2 p100 involving protection of NF-kappaB-inducing kinase (NIK) from autophagy-mediated degradation
-
Qing G, Yan P, Qu Z, et al. Hsp90 regulates processing of NF-kappaB2 p100 involving protection of NF-kappaB-inducing kinase (NIK) from autophagy-mediated degradation. Cell Res 2007;17:520-30.
-
(2007)
Cell Res
, vol.17
, pp. 520-530
-
-
Qing, G.1
Yan, P.2
Qu, Z.3
-
40
-
-
33751111683
-
Hsp90 inhibition results in autophagy-mediated proteasome-independent degradation of IkappaB kinase (IKK)
-
Qing G, Yan P, Xiao G. Hsp90 inhibition results in autophagy-mediated proteasome-independent degradation of IkappaB kinase (IKK). Cell Res 2006;16:895-901.
-
(2006)
Cell Res
, vol.16
, pp. 895-901
-
-
Qing, G.1
Yan, P.2
Xiao, G.3
-
41
-
-
33750071414
-
NF-kappaB activation represses tumor necrosis factor-alpha-induced autophagy
-
Djavaheri-Mergny M, Amelotti M, Mathieu J, et al. NF-kappaB activation represses tumor necrosis factor-alpha-induced autophagy. J Biol Chem 2006;281:30373-82.
-
(2006)
J Biol Chem
, vol.281
, pp. 30373-30382
-
-
Djavaheri-Mergny, M.1
Amelotti, M.2
Mathieu, J.3
-
42
-
-
34250333058
-
NF-kappaB inhibition sensitizes to starvation-induced cell death in high-risk myelodys-plastic syndrome and acute myeloid leukemia
-
Fabre C, Carvalho G, Tasdemir E, et al. NF-kappaB inhibition sensitizes to starvation-induced cell death in high-risk myelodys-plastic syndrome and acute myeloid leukemia. Oncogene 2007;26:4071-83.
-
(2007)
Oncogene
, vol.26
, pp. 4071-4083
-
-
Fabre, C.1
Carvalho, G.2
Tasdemir, E.3
-
43
-
-
25144457455
-
Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
-
Pattingre S, Tassa A, Qu X, et al. Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy. Cell 2005;122: 927-39.
-
(2005)
Cell
, vol.122
, pp. 927-939
-
-
Pattingre, S.1
Tassa, A.2
Qu, X.3
-
44
-
-
0042525938
-
NF-kappaB inhibits TNF-induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death
-
Sakon S, Xue X, Takekawa M, et al. NF-kappaB inhibits TNF-induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death. Embo J 2003;22:3898-909.
-
(2003)
Embo J
, vol.22
, pp. 3898-3909
-
-
Sakon, S.1
Xue, X.2
Takekawa, M.3
-
45
-
-
34250878386
-
Regulation of autophagy by NF-kappaB transcription factor and reactives oxygen species
-
Djavaheri-Mergny M, Amelotti M, Mathieu J, et al. Regulation of autophagy by NF-kappaB transcription factor and reactives oxygen species. Autophagy 2007;3:390-2.
-
(2007)
Autophagy
, vol.3
, pp. 390-392
-
-
Djavaheri-Mergny, M.1
Amelotti, M.2
Mathieu, J.3
-
46
-
-
33645521571
-
Autophagic programmed cell death by selective catalase degradation
-
Yu L, Wan F, Dutta S, et al. Autophagic programmed cell death by selective catalase degradation. Proc Natl Acad Sci U S A 2006; 103: 4952-4957.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 4952-4957
-
-
Yu, L.1
Wan, F.2
Dutta, S.3
-
47
-
-
0345166111
-
Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
-
Yue Z, Jin S, Yang C, et al. Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor. Proc Natl Acad Sci U S A 2003;100:15077-82.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 15077-15082
-
-
Yue, Z.1
Jin, S.2
Yang, C.3
-
48
-
-
34347344990
-
Ambral regulates autophagy and development of the nervous system
-
Maria Fimia G, Stoykova A, Romagnoli A, et al. Ambral regulates autophagy and development of the nervous system. Nature 2007;447:1121-5.
-
(2007)
Nature
, vol.447
, pp. 1121-1125
-
-
Maria Fimia, G.1
Stoykova, A.2
Romagnoli, A.3
-
49
-
-
1542283812
-
In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker
-
Mizushima N, Yamamoto A, Matsui M, et al. In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker. Mol Biol Cell 2004;15:1101-11.
-
(2004)
Mol Biol Cell
, vol.15
, pp. 1101-1111
-
-
Mizushima, N.1
Yamamoto, A.2
Matsui, M.3
-
50
-
-
11144245626
-
The role of autophagy during the early neonatal starvation period
-
Kuma A, Hatano M, Matsui M, et al. The role of autophagy during the early neonatal starvation period. Nature 2004;432:1032-6.
-
(2004)
Nature
, vol.432
, pp. 1032-1036
-
-
Kuma, A.1
Hatano, M.2
Matsui, M.3
-
51
-
-
34247186472
-
Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4
-
Scherz-Shouval R, Shvets E, Fass E, et al. Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4. Embo J 2007;26:1749-60.
-
(2007)
Embo J
, vol.26
, pp. 1749-1760
-
-
Scherz-Shouval, R.1
Shvets, E.2
Fass, E.3
-
52
-
-
34848920863
-
ROS, mitochondria and the regulation of autophagy
-
Scherz-Shouval R, Elazar Z. ROS, mitochondria and the regulation of autophagy. Trends Cell Biol 2007;17:422-7.
-
(2007)
Trends Cell Biol
, vol.17
, pp. 422-427
-
-
Scherz-Shouval, R.1
Elazar, Z.2
-
53
-
-
33749579383
-
Endoplasmic reticulum stress triggers autophagy
-
Yorimitsu T, Nair U, Yang Z, et al. Endoplasmic reticulum stress triggers autophagy. J Biol Chem 2006;281:30299-304.
-
(2006)
J Biol Chem
, vol.281
, pp. 30299-30304
-
-
Yorimitsu, T.1
Nair, U.2
Yang, Z.3
-
54
-
-
33644606491
-
Tracker dyes to probe mitochondrial autophagy (mitophagy) in rat hepatocytes
-
Rodriguez-Enriquez S, Kim I, Currin RT, et al. Tracker dyes to probe mitochondrial autophagy (mitophagy) in rat hepatocytes. Autophagy 2006;2:39-46.
-
(2006)
Autophagy
, vol.2
, pp. 39-46
-
-
Rodriguez-Enriquez, S.1
Kim, I.2
Currin, R.T.3
-
55
-
-
33749162486
-
Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis
-
Yousefi S, Perozzo R, Schmid I, et al. Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis. Nat Cell Biol 2006;8:1124-32.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 1124-1132
-
-
Yousefi, S.1
Perozzo, R.2
Schmid, I.3
-
56
-
-
34248998801
-
Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1
-
Maiuri MC, Le Toumelin G, Criollo A, et al. Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1. Embo J 2007;26:2527-39.
-
(2007)
Embo J
, vol.26
, pp. 2527-2539
-
-
Maiuri, M.C.1
Le Toumelin, G.2
Criollo, A.3
-
57
-
-
34250705747
-
Atg5 and Bcl-2 provide novel insights into the interplay between apoptosis and autophagy
-
Luo S, Rubinsztein DC. Atg5 and Bcl-2 provide novel insights into the interplay between apoptosis and autophagy. Cell Death Differ 2007;14:1247-50.
-
(2007)
Cell Death Differ
, vol.14
, pp. 1247-1250
-
-
Luo, S.1
Rubinsztein, D.C.2
-
59
-
-
33746359639
-
The death-associated protein kinases: Structure, function, and beyond
-
Bialik S, Kimchi A. The death-associated protein kinases: structure, function, and beyond. Annu Rev Biochem 2006;75:189-210.
-
(2006)
Annu Rev Biochem
, vol.75
, pp. 189-210
-
-
Bialik, S.1
Kimchi, A.2
-
60
-
-
20144381544
-
Essential roles of Atg5 and FADD in autophagic cell death: Dissection of autophagic cell death into vacuole formation and cell death
-
Pyo JO, Jang MH, Kwon YK, et al. Essential roles of Atg5 and FADD in autophagic cell death: dissection of autophagic cell death into vacuole formation and cell death. J Biol Chem 2005;280: 20722-9.
-
(2005)
J Biol Chem
, vol.280
, pp. 20722-20729
-
-
Pyo, J.O.1
Jang, M.H.2
Kwon, Y.K.3
-
61
-
-
33745357459
-
Autophagy as an immune defense mechanism
-
Deretic V. Autophagy as an immune defense mechanism. Curr Opin Immunol 2006;18:375-82.
-
(2006)
Curr Opin Immunol
, vol.18
, pp. 375-382
-
-
Deretic, V.1
-
62
-
-
33646340673
-
Autophagy and antigen presentation
-
Munz C. Autophagy and antigen presentation. Cell Microbiol 2006;8:891-8.
-
(2006)
Cell Microbiol
, vol.8
, pp. 891-898
-
-
Munz, C.1
-
63
-
-
31544483332
-
-
Chaplin DD. Overview of the human immune response. J Allergy Clin Immunol 2006;117 (2 Suppl Mini-Primer):S430-5.
-
Chaplin DD. Overview of the human immune response. J Allergy Clin Immunol 2006;117 (2 Suppl Mini-Primer):S430-5.
-
-
-
-
64
-
-
17644370329
-
Cell biology of antigen processing in vitro and in vivo
-
Trombetta ES, Mellman I. Cell biology of antigen processing in vitro and in vivo. Annu Rev Immunol 2005;23:975-1028.
-
(2005)
Annu Rev Immunol
, vol.23
, pp. 975-1028
-
-
Trombetta, E.S.1
Mellman, I.2
-
65
-
-
0037960005
-
Major histocompatibility complex class II-restricted presentation of a cytosolic antigen by autophagy
-
Nimmerjahn F, Milosevic S, Behrends U, et al. Major histocompatibility complex class II-restricted presentation of a cytosolic antigen by autophagy. Eur J Immunol 2003;33:1250-9.
-
(2003)
Eur J Immunol
, vol.33
, pp. 1250-1259
-
-
Nimmerjahn, F.1
Milosevic, S.2
Behrends, U.3
-
66
-
-
12844275079
-
Endogenous MHC class II processing of a viral nuclear antigen after autophagy
-
Paludan C, Schmid D, Landthaler M, et al. Endogenous MHC class II processing of a viral nuclear antigen after autophagy. Science 2005;307:593-6.
-
(2005)
Science
, vol.307
, pp. 593-596
-
-
Paludan, C.1
Schmid, D.2
Landthaler, M.3
-
67
-
-
33846068828
-
Autophagy in MHC class II antigen processing
-
Strawbridge AB, Blum JS. Autophagy in MHC class II antigen processing. Curr Opin Immunol 2007;19:87-92.
-
(2007)
Curr Opin Immunol
, vol.19
, pp. 87-92
-
-
Strawbridge, A.B.1
Blum, J.S.2
-
68
-
-
1842407189
-
-
Brazil MI, Weiss S, Stockinger B. Excessive degradation of intracellular protein in macrophages prevents presentation in the context of major histocompatibility complex class II molecules. Eur J Immunol 1997;27:1506-14.
-
Brazil MI, Weiss S, Stockinger B. Excessive degradation of intracellular protein in macrophages prevents presentation in the context of major histocompatibility complex class II molecules. Eur J Immunol 1997;27:1506-14.
-
-
-
-
69
-
-
0037546559
-
Human CD4(+) T lymphocytes consistently respond to the latent Epstein-Barr virus nuclear antigen EBNA1
-
Munz C, Bickham KL, Subklewe M, et al. Human CD4(+) T lymphocytes consistently respond to the latent Epstein-Barr virus nuclear antigen EBNA1. J Exp Med 2000;191:1649-60.
-
(2000)
J Exp Med
, vol.191
, pp. 1649-1660
-
-
Munz, C.1
Bickham, K.L.2
Subklewe, M.3
-
70
-
-
33846224369
-
Antigen-loading compartments for major histocompatibility complex class II molecules continuously receive input from autophagosomes
-
Schmid D, Pypaert M, Munz C. Antigen-loading compartments for major histocompatibility complex class II molecules continuously receive input from autophagosomes. Immunity 2007;26:79-92.
-
(2007)
Immunity
, vol.26
, pp. 79-92
-
-
Schmid, D.1
Pypaert, M.2
Munz, C.3
-
71
-
-
33947134377
-
Autophagy-dependent viral recognition by plasmacytoid dendritic cells
-
Lee HK, Lund JM, Ramanathan B, et al. Autophagy-dependent viral recognition by plasmacytoid dendritic cells. Science 2007; 315:1398-401.
-
(2007)
Science
, vol.315
, pp. 1398-1401
-
-
Lee, H.K.1
Lund, J.M.2
Ramanathan, B.3
-
72
-
-
33745847796
-
Mouse infection by Legionella, a model to analyze autophagy
-
Dubuisson JF, Swanson MS. Mouse infection by Legionella, a model to analyze autophagy. Autophagy 2006;2:179-82.
-
(2006)
Autophagy
, vol.2
, pp. 179-182
-
-
Dubuisson, J.F.1
Swanson, M.S.2
-
73
-
-
34447643958
-
Toll-like receptor 4 is a sensor for autophagy associated with innate immunity
-
Xu Y, Jagannath C, Liu XD, et al. Toll-like receptor 4 is a sensor for autophagy associated with innate immunity. Immunity 2007; 27:135-44.
-
(2007)
Immunity
, vol.27
, pp. 135-144
-
-
Xu, Y.1
Jagannath, C.2
Liu, X.D.3
-
74
-
-
33744958258
-
Autophagy controls Salmonella infection in response to damage to the Salmonella-containing vacuole
-
Birmingham CL, Smith AC, Bakowski MA, et al. Autophagy controls Salmonella infection in response to damage to the Salmonella-containing vacuole. J Biol Chem 2006;281:11374-83.
-
(2006)
J Biol Chem
, vol.281
, pp. 11374-11383
-
-
Birmingham, C.L.1
Smith, A.C.2
Bakowski, M.A.3
-
75
-
-
10944253145
-
Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages
-
Gutierrez MG, Master SS, Singh SB, et al. Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages. Cell 2004;119:753-66.
-
(2004)
Cell
, vol.119
, pp. 753-766
-
-
Gutierrez, M.G.1
Master, S.S.2
Singh, S.B.3
-
76
-
-
33748506089
-
Human IRGM induces autophagy to eliminate intracellular mycobacteria
-
Singh SB, Davis AS, Taylor GA, et al. Human IRGM induces autophagy to eliminate intracellular mycobacteria. Science 2006;313:1438-41.
-
(2006)
Science
, vol.313
, pp. 1438-1441
-
-
Singh, S.B.1
Davis, A.S.2
Taylor, G.A.3
-
77
-
-
1842430006
-
Bacterial invasion: The paradigms of enteroinvasive pathogens
-
Cossart P, Sansonetti PJ. Bacterial invasion: the paradigms of enteroinvasive pathogens. Science 2004;304:242-8.
-
(2004)
Science
, vol.304
, pp. 242-248
-
-
Cossart, P.1
Sansonetti, P.J.2
-
78
-
-
13244256806
-
Escape of intracellular Shigella from autophagy
-
Ogawa M, Yoshimori T, Suzuki T, et al. Escape of intracellular Shigella from autophagy. Science 2005;307:727-31.
-
(2005)
Science
, vol.307
, pp. 727-731
-
-
Ogawa, M.1
Yoshimori, T.2
Suzuki, T.3
-
79
-
-
34248574063
-
Autophagy: A pathogen driven process
-
Colombo MI. Autophagy: a pathogen driven process. IUBMB Life 2007;59:238-42.
-
(2007)
IUBMB Life
, vol.59
, pp. 238-242
-
-
Colombo, M.I.1
-
80
-
-
34548434775
-
-
Suzuki T, Franchi L, Toma C, et al. Differential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigella-infected macrophages. PLoS Pathog 2007;3:elll.
-
Suzuki T, Franchi L, Toma C, et al. Differential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigella-infected macrophages. PLoS Pathog 2007;3:elll.
-
-
-
-
81
-
-
0031797897
-
Brucella abortus transits through the autophagic pathway and replicates in the endoplasmic reticulum of nonprofessional phagocytes
-
Pizarro-Cerda J, Meresse S, Partom RG, et al. Brucella abortus transits through the autophagic pathway and replicates in the endoplasmic reticulum of nonprofessional phagocytes. Infect Im-mun 1998;66:5711-24.
-
(1998)
Infect Im-mun
, vol.66
, pp. 5711-5724
-
-
Pizarro-Cerda, J.1
Meresse, S.2
Partom, R.G.3
-
82
-
-
19644382161
-
Autophagy is an immediate macrophage response to Legionella pneumophila
-
Amer AO, Swanson MS. Autophagy is an immediate macrophage response to Legionella pneumophila. Cell Microbiol 2005;7:765-78.
-
(2005)
Cell Microbiol
, vol.7
, pp. 765-778
-
-
Amer, A.O.1
Swanson, M.S.2
-
83
-
-
33846936157
-
Protective role of autophagy against Vibrio cholerae cytolysin, a pore-forming toxin from V. cholerae
-
Gutierrez MG, Saka HA, Chinen I, et al. Protective role of autophagy against Vibrio cholerae cytolysin, a pore-forming toxin from V. cholerae. Proc Natl Acad Sci USA 2007; 104:1829-34.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 1829-1834
-
-
Gutierrez, M.G.1
Saka, H.A.2
Chinen, I.3
-
84
-
-
34547176642
-
Unravelling the pathogenesis of inflammatory bowel disease
-
Xavier RJ, Podolsky DK. Unravelling the pathogenesis of inflammatory bowel disease. Nature 2007;448:427-34.
-
(2007)
Nature
, vol.448
, pp. 427-434
-
-
Xavier, R.J.1
Podolsky, D.K.2
-
85
-
-
34248136828
-
Inflammatory bowel disease: Cause and immunobiology
-
Baumgart DC, Carding SR. Inflammatory bowel disease: cause and immunobiology. Lancet 2007;369:1627-40.
-
(2007)
Lancet
, vol.369
, pp. 1627-1640
-
-
Baumgart, D.C.1
Carding, S.R.2
-
86
-
-
34548163868
-
Confirmation of the role of ATG16L1 as a Crohn's disease susceptibility gene
-
Cummings JR, Cooney R, Pathan S, et al. Confirmation of the role of ATG16L1 as a Crohn's disease susceptibility gene. Inflamm Bowel Dis 2007;13:941-6.
-
(2007)
Inflamm Bowel Dis
, vol.13
, pp. 941-946
-
-
Cummings, J.R.1
Cooney, R.2
Pathan, S.3
-
87
-
-
33846627302
-
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
-
Hampe J, Franke A, Rosenstiel P, et al. A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1. Nat Genet 2007;39:207-11.
-
(2007)
Nat Genet
, vol.39
, pp. 207-211
-
-
Hampe, J.1
Franke, A.2
Rosenstiel, P.3
-
88
-
-
34347338690
-
Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility
-
Parkes M, Barrett JC, Prescott NJ, et al. Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility. Nat Genet 2007;39:830-2.
-
(2007)
Nat Genet
, vol.39
, pp. 830-832
-
-
Parkes, M.1
Barrett, J.C.2
Prescott, N.J.3
-
89
-
-
34247566585
-
A nonsynonymous SNP in ATG16L1 predisposes to ileal Crohn's disease and is independent of CARD15 and IBD5
-
Prescott NJ, Fisher SA, Franke A, et al. A nonsynonymous SNP in ATG16L1 predisposes to ileal Crohn's disease and is independent of CARD15 and IBD5. Gastroenterology 2007;132:1665-71.
-
(2007)
Gastroenterology
, vol.132
, pp. 1665-1671
-
-
Prescott, N.J.1
Fisher, S.A.2
Franke, A.3
-
90
-
-
34547211759
-
Association of the T300A non-synonymous variant of the ATG16L1 gene with susceptibility to paediatric Crohn's disease
-
Baldassano RN, Bradfield JP, Monos DS, et al. Association of the T300A non-synonymous variant of the ATG16L1 gene with susceptibility to paediatric Crohn's disease. Gut 2007;56:1171-3.
-
(2007)
Gut
, vol.56
, pp. 1171-1173
-
-
Baldassano, R.N.1
Bradfield, J.P.2
Monos, D.S.3
-
91
-
-
34347335667
-
Guilt beyond a reasonable doubt
-
Altshuler D, Daly M. Guilt beyond a reasonable doubt. Nat Genet 2007;39:813-5.
-
(2007)
Nat Genet
, vol.39
, pp. 813-815
-
-
Altshuler, D.1
Daly, M.2
-
92
-
-
34347357508
-
Association analysis of genetic variants in IL23R, ATG16L1 and 5pl3. 1 loci with Crohn's disease in Japanese patients
-
Yamazaki K, Onouchi Y, Takazoe M, et al. Association analysis of genetic variants in IL23R, ATG16L1 and 5pl3. 1 loci with Crohn's disease in Japanese patients. J Hum Genet 2007;52:575-83.
-
(2007)
J Hum Genet
, vol.52
, pp. 575-583
-
-
Yamazaki, K.1
Onouchi, Y.2
Takazoe, M.3
-
93
-
-
85047683832
-
Liver injury in alphal-antitrypsin deficiency: An aggregated protein induces mitochondrial injury
-
Perlmutter DH. Liver injury in alphal-antitrypsin deficiency: an aggregated protein induces mitochondrial injury. J Clin Invest 2002;110:1579-83.
-
(2002)
J Clin Invest
, vol.110
, pp. 1579-1583
-
-
Perlmutter, D.H.1
-
94
-
-
0026755363
-
The mechanism of Z alpha 1-antitrypsin accumulation in the liver
-
Lomas DA, Evans DL, Finch JT, et al. The mechanism of Z alpha 1-antitrypsin accumulation in the liver. Nature 1992;357:605-7.
-
(1992)
Nature
, vol.357
, pp. 605-607
-
-
Lomas, D.A.1
Evans, D.L.2
Finch, J.T.3
-
95
-
-
33748419472
-
The role of autophagy in alpha-1-antitrypsin deficiency: A specific cellular response in genetic diseases associated with aggregation-prone proteins
-
Perlmutter DH. The role of autophagy in alpha-1-antitrypsin deficiency: a specific cellular response in genetic diseases associated with aggregation-prone proteins. Autophagy 2006;2:258-63.
-
(2006)
Autophagy
, vol.2
, pp. 258-263
-
-
Perlmutter, D.H.1
-
96
-
-
33645216184
-
Intracellular inclusions containing mutant alphal-antitrypsin Z are propagated in the absence of autophagic activity
-
Kamimoto T, Shoji S, Hidvegi T, et al. Intracellular inclusions containing mutant alphal-antitrypsin Z are propagated in the absence of autophagic activity. J Biol Chem 2006;281:4467-76.
-
(2006)
J Biol Chem
, vol.281
, pp. 4467-4476
-
-
Kamimoto, T.1
Shoji, S.2
Hidvegi, T.3
-
97
-
-
1542466459
-
Alphal-antitrypsin deficiency: Liver disease associated with retention of a mutant secretory glycoprotein in the endoplasmic reticulum
-
Perlmutter DH. Alphal-antitrypsin deficiency: liver disease associated with retention of a mutant secretory glycoprotein in the endoplasmic reticulum. Methods Mol Biol 2003;232:39-56.
-
(2003)
Methods Mol Biol
, vol.232
, pp. 39-56
-
-
Perlmutter, D.H.1
-
98
-
-
0033671965
-
Retention of mutant alpha(1)-antitrypsin Z in endoplasmic reticulum is associated with an autophagic response
-
Teckman JH, Perlmutter DH. Retention of mutant alpha(1)-antitrypsin Z in endoplasmic reticulum is associated with an autophagic response. Am J Physiol Gastrointest Liver Physiol 2000; 279:G961-74.
-
(2000)
Am J Physiol Gastrointest Liver Physiol
, vol.279
-
-
Teckman, J.H.1
Perlmutter, D.H.2
-
99
-
-
30044436220
-
Characterization of an ERAD gene as VPS30/ATG6 reveals two alternative and functionally distinct protein quality control pathways: One for soluble Z variant of human alpha-1 proteinase inhibitor (AlPiZ) and another for aggregates of AlPiZ
-
Kruse KB, Brodsky JL, McCracken AA. Characterization of an ERAD gene as VPS30/ATG6 reveals two alternative and functionally distinct protein quality control pathways: one for soluble Z variant of human alpha-1 proteinase inhibitor (AlPiZ) and another for aggregates of AlPiZ. Mol Biol Cell 2006;17:203-12.
-
(2006)
Mol Biol Cell
, vol.17
, pp. 203-212
-
-
Kruse, K.B.1
Brodsky, J.L.2
McCracken, A.A.3
-
100
-
-
0036840471
-
Fasting in alphal-antitrypsin deficient liver: Constitutive [correction of consultative] activation of autophagy
-
Teckman JH, An JK, Loethen S, et al. Fasting in alphal-antitrypsin deficient liver: constitutive [correction of consultative] activation of autophagy. Am J Physiol Gastrointest Liver Physiol 2002; 283:G1156-65.
-
(2002)
Am J Physiol Gastrointest Liver Physiol
, vol.283
-
-
Teckman, J.H.1
An, J.K.2
Loethen, S.3
-
103
-
-
0348013126
-
Autophagy regulates the processing of amino terminal huntington fragments
-
Qin ZH, Wang Y, Kegel KB, et al. Autophagy regulates the processing of amino terminal huntington fragments. Hum Mol Genet 2003;12:3231-44.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 3231-3244
-
-
Qin, Z.H.1
Wang, Y.2
Kegel, K.B.3
-
104
-
-
34248994604
-
Small molecules enhance autophagy and reduce toxicity in Huntington's disease models
-
Sarkar S, Perlstein EO, Imarisio S, et al. Small molecules enhance autophagy and reduce toxicity in Huntington's disease models. Nat Chem Biol 2007;3:331-8.
-
(2007)
Nat Chem Biol
, vol.3
, pp. 331-338
-
-
Sarkar, S.1
Perlstein, E.O.2
Imarisio, S.3
-
105
-
-
26444515364
-
Autophagy and its possible roles in nervous system diseases, damage and repair
-
Rubinsztein DC, DiFiglia M, Heintz N, et al. Autophagy and its possible roles in nervous system diseases, damage and repair. Autophagy 2005;1:11-22.
-
(2005)
Autophagy
, vol.1
, pp. 11-22
-
-
Rubinsztein, D.C.1
DiFiglia, M.2
Heintz, N.3
-
107
-
-
0030863352
-
Niemann-Pick C1 disease gene: Homology to mediators of cholesterol homeostasis
-
Carstea ED, Morris JA, Coleman KG, et al. Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis. Science 1997;277:228-31.
-
(1997)
Science
, vol.277
, pp. 228-231
-
-
Carstea, E.D.1
Morris, J.A.2
Coleman, K.G.3
-
108
-
-
34548068588
-
Lipid trafficking defects increase beclin-1 and activate autophagy in Niemann-Pick type C disease
-
Pacheco CD, Lieberman AP Lipid trafficking defects increase beclin-1 and activate autophagy in Niemann-Pick type C disease. Autophagy 2007;3:487-9.
-
(2007)
Autophagy
, vol.3
, pp. 487-489
-
-
Pacheco, C.D.1
Lieberman, A.P.2
-
109
-
-
34447302577
-
Autophagy in Niemann-Pick C disease is dependent upon Beclin-1 and responsive to lipid trafficking defects
-
Pacheco CD, Kunkel R, Lieberman AP. Autophagy in Niemann-Pick C disease is dependent upon Beclin-1 and responsive to lipid trafficking defects. Hum Mol Genet 2007;16:1495-503.
-
(2007)
Hum Mol Genet
, vol.16
, pp. 1495-1503
-
-
Pacheco, C.D.1
Kunkel, R.2
Lieberman, A.P.3
-
110
-
-
0026507099
-
Turnover of peroxisomal vesicles by autophagic proteolysis in cultured fibroblasts from Zellweger patients
-
Heikoop JC, van den Berg M, Strijland A, et al. Turnover of peroxisomal vesicles by autophagic proteolysis in cultured fibroblasts from Zellweger patients. Eur J Cell Biol 1992;57:165-71.
-
(1992)
Eur J Cell Biol
, vol.57
, pp. 165-171
-
-
Heikoop, J.C.1
van den Berg, M.2
Strijland, A.3
-
111
-
-
0026695199
-
Familial microvillous atrophy: A clinico-pathological survey of 23 cases
-
Phillips AD, Schmitz J. Familial microvillous atrophy: a clinico-pathological survey of 23 cases. J Pediatr Gastroenterol Nutr 1992;14:380-96.
-
(1992)
J Pediatr Gastroenterol Nutr
, vol.14
, pp. 380-396
-
-
Phillips, A.D.1
Schmitz, J.2
-
112
-
-
0021815019
-
Congenital microvillous atrophy: Specific diagnostic features
-
Phillips AD, Jenkins P. Congenital microvillous atrophy: specific diagnostic features. Arch Dis Child 1985;60:135-40.
-
(1985)
Arch Dis Child
, vol.60
, pp. 135-140
-
-
Phillips, A.D.1
Jenkins, P.2
-
113
-
-
0036786887
-
Autophagocytosis of the apical membrane in microvillus inclusion disease
-
Reinshagen K, Nairn HY, Zimmer KP Autophagocytosis of the apical membrane in microvillus inclusion disease. Gut 2002; 51:514-21.
-
(2002)
Gut
, vol.51
, pp. 514-521
-
-
Reinshagen, K.1
Nairn, H.Y.2
Zimmer, K.P.3
-
114
-
-
0024509966
-
Microvillus inclusion disease: An inherited defect of brush-border assembly and differentiation
-
Cutz E, Rhoads JM, Drumm B, et al. Microvillus inclusion disease: an inherited defect of brush-border assembly and differentiation. N Engl J Med 1989;320:646-51.
-
(1989)
N Engl J Med
, vol.320
, pp. 646-651
-
-
Cutz, E.1
Rhoads, J.M.2
Drumm, B.3
-
115
-
-
34447519003
-
The Rab8 GTPase regulates apical protein localization in intestinal cells
-
Sato T, Mushiake S, Kato Y, et al. The Rab8 GTPase regulates apical protein localization in intestinal cells. Nature 2007;448:366-9.
-
(2007)
Nature
, vol.448
, pp. 366-369
-
-
Sato, T.1
Mushiake, S.2
Kato, Y.3
-
116
-
-
33846244269
-
Role of autophagy in cancer: Management of metabolic stress
-
Jin S, White E. Role of autophagy in cancer: management of metabolic stress. Autophagy 2007;3:28-31.
-
(2007)
Autophagy
, vol.3
, pp. 28-31
-
-
Jin, S.1
White, E.2
-
117
-
-
34247528572
-
Early endosomes associated with dynamic F-actin structures are required for late trafficking of H. pylori VacA toxin
-
Gauthier NC, Monzo P, Gonzalez T, et al. Early endosomes associated with dynamic F-actin structures are required for late trafficking of H. pylori VacA toxin. J Cell Biol 2007;177:343-54.
-
(2007)
J Cell Biol
, vol.177
, pp. 343-354
-
-
Gauthier, N.C.1
Monzo, P.2
Gonzalez, T.3
-
118
-
-
33646271855
-
A matter of life or death (or both): Understanding autophagy in cancer
-
Hait WN, Jin S, Yang JM. A matter of life or death (or both): understanding autophagy in cancer. Clin Cancer Res 2006; 12 (7 Pt l):1961-5.
-
(2006)
Clin Cancer Res
, vol.12
, Issue.7 PART L
, pp. 1961-1965
-
-
Hait, W.N.1
Jin, S.2
Yang, J.M.3
-
119
-
-
25444440875
-
The role of autophagy in cancer development and response to therapy
-
Kondo Y, Kanzawa T, Sawaya R, et al. The role of autophagy in cancer development and response to therapy. Nat Rev Cancer 2005;5:726-34.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 726-734
-
-
Kondo, Y.1
Kanzawa, T.2
Sawaya, R.3
-
120
-
-
33745751085
-
Autophagic and tumour suppressor activity of a novel Beclinl-binding protein UVRAG
-
Liang C, Feng P, Ku B, et al. Autophagic and tumour suppressor activity of a novel Beclinl-binding protein UVRAG. Nat Cell Biol 2006;8:688-99.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 688-699
-
-
Liang, C.1
Feng, P.2
Ku, B.3
-
121
-
-
0000906170
-
Induction of autophagy and inhibition of tumorigenesis by beclin 1
-
Liang XH, Jackson S, Seaman M, et al. Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature 1999;402:672-6.
-
(1999)
Nature
, vol.402
, pp. 672-676
-
-
Liang, X.H.1
Jackson, S.2
Seaman, M.3
-
122
-
-
9144240441
-
Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene
-
Qu X, Yu J, Bhagat G, et al. Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene. J Clin Invest 2003;112:1809-20.
-
(2003)
J Clin Invest
, vol.112
, pp. 1809-1820
-
-
Qu, X.1
Yu, J.2
Bhagat, G.3
-
123
-
-
33846204370
-
UVRAG: A new player in autophagy and tumor cell growth
-
Liang C, Feng P, Ku B, et al. UVRAG: a new player in autophagy and tumor cell growth. Autophagy 2007;3:69-71.
-
(2007)
Autophagy
, vol.3
, pp. 69-71
-
-
Liang, C.1
Feng, P.2
Ku, B.3
-
124
-
-
33947099498
-
Mammalian target of rapamycin is activated in human gastric cancer and serves as a target for therapy in an experimental model
-
Lang SA, Gaumann A, Koehl GE, et al. Mammalian target of rapamycin is activated in human gastric cancer and serves as a target for therapy in an experimental model. Int J Cancer 2007; 120:1803-10.
-
(2007)
Int J Cancer
, vol.120
, pp. 1803-1810
-
-
Lang, S.A.1
Gaumann, A.2
Koehl, G.E.3
-
125
-
-
34548089170
-
Rapamycin inhibits multiple stages of c-Neu/ErbB2 induced tumor progression in a transgenic mouse model of HER2-positive breast cancer
-
Mosley JD, Poirier JT, Seachrist DD, et al. Rapamycin inhibits multiple stages of c-Neu/ErbB2 induced tumor progression in a transgenic mouse model of HER2-positive breast cancer. Mol Cancer Ther 2007;6:2188-97.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 2188-2197
-
-
Mosley, J.D.1
Poirier, J.T.2
Seachrist, D.D.3
-
126
-
-
33745885329
-
DRAM, a p53-induced modulator of autophagy, is critical for apoptosis
-
Crighton D, Wilkinson S, O'Prey J, et al. DRAM, a p53-induced modulator of autophagy, is critical for apoptosis. Cell 2006;126:121-34.
-
(2006)
Cell
, vol.126
, pp. 121-134
-
-
Crighton, D.1
Wilkinson, S.2
O'Prey, J.3
-
128
-
-
17144427728
-
Synergistic augmentation of rapamycin-induced autophagy in malignant glioma cells by phosphatidylinositol 3-kinase/protein kinase B inhibitors
-
Takeuchi H, Kondo Y, Fujiwara K, et al. Synergistic augmentation of rapamycin-induced autophagy in malignant glioma cells by phosphatidylinositol 3-kinase/protein kinase B inhibitors. Cancer Res 2005;65:3336-46.
-
(2005)
Cancer Res
, vol.65
, pp. 3336-3346
-
-
Takeuchi, H.1
Kondo, Y.2
Fujiwara, K.3
-
129
-
-
30044446136
-
Curcumin (diferuloyl-methane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IkappaBalpha kinase and Akt activation
-
Aggarwal S, Ichikawa H, Takada Y, et al. Curcumin (diferuloyl-methane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IkappaBalpha kinase and Akt activation. Mol Pharmacol 2006;69:195-206.
-
(2006)
Mol Pharmacol
, vol.69
, pp. 195-206
-
-
Aggarwal, S.1
Ichikawa, H.2
Takada, Y.3
-
130
-
-
34347238938
-
Evidence that curcumin suppresses the growth of malignant gliomas in vitro and in vivo through induction of autophagy: Role of Akt and extracellular signal-regulated kinase signaling pathways
-
Aoki H, Takada Y, Kondo S, et al. Evidence that curcumin suppresses the growth of malignant gliomas in vitro and in vivo through induction of autophagy: role of Akt and extracellular signal-regulated kinase signaling pathways. Mol Pharmacol 2007; 72:29-39.
-
(2007)
Mol Pharmacol
, vol.72
, pp. 29-39
-
-
Aoki, H.1
Takada, Y.2
Kondo, S.3
|