Hsp90 regulates processing of NF-kB2 p100 involving protection of NF-kB-inducing kinase (NIK) from autophagy-mediated degradation

Cell Research

Volumn 17, Issue 6, 2007, Pages 520-530

  Qing, Guoliang ^a   Yan, Pengrong ^a   Qu, Zhaoxia ^a   Liu, Hudan ^a   Xiao, Gutian ^a  

^a RUTGERS UNIVERSITY   (United States)

Author keywords

autophagy; geldanamycin; Hsp90; NF ?B2; NIK; proteasome independent degradation

Indexed keywords

ANTINEOPLASTIC ANTIBIOTIC; BENZOQUINONE DERIVATIVE; GELDANAMYCIN; HEAT SHOCK PROTEIN 90; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MACROCYCLIC LACTAM; NF KAPPA B KINASE; NF-KAPPA B KINASE; PROTEIN SERINE THREONINE KINASE; UNCLASSIFIED DRUG;

ANIMAL; AUTOPHAGY; CELL LINE; DRUG EFFECT; HUMAN; METABOLISM; MOUSE; MOUSE MUTANT; PHYSIOLOGY; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; AUTOPHAGY; BENZOQUINONES; CELL LINE; HSP90 HEAT-SHOCK PROTEINS; HUMANS; LACTAMS, MACROCYCLIC; MICE; MICE, KNOCKOUT; NF-KAPPA B P52 SUBUNIT; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION;

EID: 34250886966     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/cr.2007.47     Document Type: Review

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