Autophagy in Niemann-Pick C disease is dependent upon Beclin-1 and responsive to lipid trafficking defects

Human Molecular Genetics

Volumn 16, Issue 12, 2007, Pages 1495-1503

  Pacheco, Chris D ^a   Kunkel, Robin ^a   Lieberman, Andrew P ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; MICROTUBULE ASSOCIATED PROTEIN 1; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY U18666A; PROTEIN BECLIN 1; PROTEIN KINASE B; S6 KINASE; SMALL INTERFERING RNA; SPHINGOLIPID; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; AUTOPHAGY; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; ENZYME ACTIVATION; FIBROBLAST; GAUCHER DISEASE; GENE MUTATION; HUMAN; HUMAN CELL; LIPID TRANSPORT; MOUSE; NIEMANN PICK DISEASE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SANDHOFF DISEASE; UPREGULATION;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; BIOLOGICAL TRANSPORT; CELLS, CULTURED; CHOLESTEROL; FIBROBLASTS; HUMANS; MEMBRANE PROTEINS; MICE; MICE, INBRED BALB C; NIEMANN-PICK DISEASES; PROTEINS; SPHINGOLIPIDS;

MUS;

EID: 34447302577     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddm100     Document Type: Article

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