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Volumn 17, Issue 3, 2008, Pages 423-439

Peripherally administered human umbilical cord blood cells reduce parenchymal and vascular β-amyloid deposits in Alzheimer mice

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; CD40 ANTIGEN; CD40 LIGAND; GAMMA INTERFERON; GLIAL FIBRILLARY ACIDIC PROTEIN; IMMUNOGLOBULIN M;

EID: 46749104502     PISSN: 15473287     EISSN: None     Source Type: Journal    
DOI: 10.1089/scd.2008.0018     Document Type: Article
Times cited : (96)

References (83)
  • 3
    • 0037393454 scopus 로고    scopus 로고
    • Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: A case report
    • Nicoll JA, D Wilkinson, C Holmes, P Steart, H Markham and RO Weller. (2003). Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: a case report. Nature Med 9:448-452.
    • (2003) Nature Med , vol.9 , pp. 448-452
    • Nicoll, J.A.1    Wilkinson, D.2    Holmes, C.3    Steart, P.4    Markham, H.5    Weller, R.O.6
  • 5
    • 0035503597 scopus 로고    scopus 로고
    • The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse
    • Lim GP, T Chu, F Yang, W Beech, SA Frautschy and GM Cole. (2001). The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse. J Neurosci 21:8370-8377.
    • (2001) J Neurosci , vol.21 , pp. 8370-8377
    • Lim, G.P.1    Chu, T.2    Yang, F.3    Beech, W.4    Frautschy, S.A.5    Cole, G.M.6
  • 10
    • 33646261886 scopus 로고    scopus 로고
    • CD40 deficiency mitigates Alzheimer's disease pathology in transgenic mouse models
    • Laporte V, G Ait-Ghezala, CH Volmar and M Mullan. (2006). CD40 deficiency mitigates Alzheimer's disease pathology in transgenic mouse models. J Neuroinflammation 3:3.
    • (2006) J Neuroinflammation , vol.3 , pp. 3
    • Laporte, V.1    Ait-Ghezala, G.2    Volmar, C.H.3    Mullan, M.4
  • 12
    • 0036667394 scopus 로고    scopus 로고
    • CD40-CD40L interaction in Alzheimer's disease
    • Tan J, T Town and M Mullan. (2002). CD40-CD40L interaction in Alzheimer's disease. Curr Opin Pharmacol 2:445-451.
    • (2002) Curr Opin Pharmacol , vol.2 , pp. 445-451
    • Tan, J.1    Town, T.2    Mullan, M.3
  • 14
    • 0034802625 scopus 로고    scopus 로고
    • CD40 signaling and Alzheimer's disease pathogenesis
    • Town T, J Tan and M Mullan. (2001). CD40 signaling and Alzheimer's disease pathogenesis. Neurochem Int 39:371-380.
    • (2001) Neurochem Int , vol.39 , pp. 371-380
    • Town, T.1    Tan, J.2    Mullan, M.3
  • 16
    • 0036149449 scopus 로고    scopus 로고
    • Identification of CD40 ligand in Alzheimer's disease and in animal models of Alzheimer's disease and brain injury
    • Calingasan NY, HA Erdely and CA Altar. (2002). Identification of CD40 ligand in Alzheimer's disease and in animal models of Alzheimer's disease and brain injury. Neurobiol Aging 23:31-39.
    • (2002) Neurobiol Aging , vol.23 , pp. 31-39
    • Calingasan, N.Y.1    Erdely, H.A.2    Altar, C.A.3
  • 17
    • 0034571241 scopus 로고    scopus 로고
    • Expression of CD40 in the brain of Alzheimer's disease and other neurological diseases
    • Togo T, H Akiyama, H Kondo, K Ikeda, M Kato, E Iseki and K Kosaka. (2000). Expression of CD40 in the brain of Alzheimer's disease and other neurological diseases. Brain Res 885:117-121.
    • (2000) Brain Res , vol.885 , pp. 117-121
    • Togo, T.1    Akiyama, H.2    Kondo, H.3    Ikeda, K.4    Kato, M.5    Iseki, E.6    Kosaka, K.7
  • 19
    • 4744341332 scopus 로고    scopus 로고
    • Infusion of human umbilical cord blood cells in a rat model of stroke dose-dependently rescues behavioral deficits and reduces infarct volume
    • Vendrame M, J Cassady, J Newcomb, T Butler, KR Pennypacker, T Zigova, CD Sanberg, PR Sanberg and AE Willing. (2004). Infusion of human umbilical cord blood cells in a rat model of stroke dose-dependently rescues behavioral deficits and reduces infarct volume. Stroke 35:2390-2395.
    • (2004) Stroke , vol.35 , pp. 2390-2395
    • Vendrame, M.1    Cassady, J.2    Newcomb, J.3    Butler, T.4    Pennypacker, K.R.5    Zigova, T.6    Sanberg, C.D.7    Sanberg, P.R.8    Willing, A.E.9
  • 22
    • 33845438887 scopus 로고    scopus 로고
    • Human umbilical cord blood progenitor cells are attracted to infarcted myocardium and significantly reduce myocardial infarction size
    • Henning RJ, JD Burgos, L Ondrovic, P Sanberg, J Balis and MB Morgan. (2006). Human umbilical cord blood progenitor cells are attracted to infarcted myocardium and significantly reduce myocardial infarction size. Cell Transplant 15:647-658.
    • (2006) Cell Transplant , vol.15 , pp. 647-658
    • Henning, R.J.1    Burgos, J.D.2    Ondrovic, L.3    Sanberg, P.4    Balis, J.5    Morgan, M.B.6
  • 23
    • 0034800757 scopus 로고    scopus 로고
    • Human umbilical cord blood cells ameliorate Alzheimer's disease in transgenic mice
    • Ende N, R Chen and D Ende-Harris. (2001). Human umbilical cord blood cells ameliorate Alzheimer's disease in transgenic mice. J Med 32:241-247.
    • (2001) J Med , vol.32 , pp. 241-247
    • Ende, N.1    Chen, R.2    Ende-Harris, D.3
  • 34
    • 0029973286 scopus 로고    scopus 로고
    • Cerebral amyloid angiopathy in the brains of patients with Alzheimer's disease: The CERAD experience, Part XV
    • Ellis RJ, JM Olichney, LJ Thal, SS Mirra, JC Morris, D Beekly and A Heyman. (1996). Cerebral amyloid angiopathy in the brains of patients with Alzheimer's disease: the CERAD experience, Part XV. Neurology 46:1592-1596.
    • (1996) Neurology , vol.46 , pp. 1592-1596
    • Ellis, R.J.1    Olichney, J.M.2    Thal, L.J.3    Mirra, S.S.4    Morris, J.C.5    Beekly, D.6    Heyman, A.7
  • 35
    • 0035099136 scopus 로고    scopus 로고
    • Structural and functional disruption of vascular smooth muscle cells in a transgenic mouse model of amyloid angiopathy
    • Christie R, M Yamada, M Moskowitz and B Hyman. (2001). Structural and functional disruption of vascular smooth muscle cells in a transgenic mouse model of amyloid angiopathy. Am J Pathol 158:1065-1071.
    • (2001) Am J Pathol , vol.158 , pp. 1065-1071
    • Christie, R.1    Yamada, M.2    Moskowitz, M.3    Hyman, B.4
  • 38
    • 0345275964 scopus 로고    scopus 로고
    • Association of aortic atherosclerosis with cerebral beta-amyloidosis and learning deficits in a mouse model of Alzheimer's disease
    • Li L, D Cao, DW Garber, H Kim and K Fukuchi. (2003). Association of aortic atherosclerosis with cerebral beta-amyloidosis and learning deficits in a mouse model of Alzheimer's disease. Am J Pathol 163:2155-2164.
    • (2003) Am J Pathol , vol.163 , pp. 2155-2164
    • Li, L.1    Cao, D.2    Garber, D.W.3    Kim, H.4    Fukuchi, K.5
  • 40
    • 0026783591 scopus 로고
    • Ultrastructure of the microglia that phagocytose amyloid and the microglia that produce beta-amyloid fibrils
    • Frackowiak J, HM Wisniewski, J Wegiel, GS Merz, K Iqbal and KC Wang. (1992). Ultrastructure of the microglia that phagocytose amyloid and the microglia that produce beta-amyloid fibrils. Acta Neuropathol (Berl) 84:225-233.
    • (1992) Acta Neuropathol (Berl) , vol.84 , pp. 225-233
    • Frackowiak, J.1    Wisniewski, H.M.2    Wegiel, J.3    Merz, G.S.4    Iqbal, K.5    Wang, K.C.6
  • 41
    • 0035696320 scopus 로고    scopus 로고
    • The inflammation-induced pathological chaperones ACT and apo-E are necessary catalysts of Alzheimer amyloid formation
    • Potter H, IM Wefes and LN Nilsson. (2001). The inflammation-induced pathological chaperones ACT and apo-E are necessary catalysts of Alzheimer amyloid formation. Neurobiol Aging 22:923-930.
    • (2001) Neurobiol Aging , vol.22 , pp. 923-930
    • Potter, H.1    Wefes, I.M.2    Nilsson, L.N.3
  • 43
    • 0032756061 scopus 로고    scopus 로고
    • Ligation of microglial CD40 results in p44/42 mitogen-activated protein kinase-dependent TNF-alpha production that is opposed by TGF-beta 1 and IL-10
    • Tan J, T Town, M Saxe, D Paris, Y Wu and M Mullan. (1999). Ligation of microglial CD40 results in p44/42 mitogen-activated protein kinase-dependent TNF-alpha production that is opposed by TGF-beta 1 and IL-10. J Immunol 163:6614-6621.
    • (1999) J Immunol , vol.163 , pp. 6614-6621
    • Tan, J.1    Town, T.2    Saxe, M.3    Paris, D.4    Wu, Y.5    Mullan, M.6
  • 44
    • 0031944607 scopus 로고    scopus 로고
    • CD40 and CD154 in cell-mediated immunity
    • Grewal IS and RA Flavell. (1998). CD40 and CD154 in cell-mediated immunity. Annu Rev Immunol 16:111-135.
    • (1998) Annu Rev Immunol , vol.16 , pp. 111-135
    • Grewal, I.S.1    Flavell, R.A.2
  • 45
    • 0031977605 scopus 로고    scopus 로고
    • The role of CD40/CD154 interactions in the priming, differentiation, and effector function of helper and cytotoxic T cells
    • Mackey MF, RJ Barth, Jr. and RJ Noelle. (1998). The role of CD40/CD154 interactions in the priming, differentiation, and effector function of helper and cytotoxic T cells. J Leukoc Biol 63:418-428.
    • (1998) J Leukoc Biol , vol.63 , pp. 418-428
    • Mackey, M.F.1    Barth Jr., R.J.2    Noelle, R.J.3
  • 46
    • 33745198969 scopus 로고    scopus 로고
    • Cytokines produced by cultured human umbilical cord blood (HUCB) cells: Implications for brain repair
    • Newman MB, AE Willing, JJ Manresa, CD Sanberg and PR Sanberg. (2006). Cytokines produced by cultured human umbilical cord blood (HUCB) cells: implications for brain repair. Exp Neurol 199:201-208.
    • (2006) Exp Neurol , vol.199 , pp. 201-208
    • Newman, M.B.1    Willing, A.E.2    Manresa, J.J.3    Sanberg, C.D.4    Sanberg, P.R.5
  • 47
    • 0037155581 scopus 로고    scopus 로고
    • Brain to plasma amyloid-beta efflux: A measure of brain amyloid burden in a mouse model of Alzheimer's disease
    • DeMattos RB, KR Bales, DJ Cummins, SM Paul and DM Holtzman. (2002). Brain to plasma amyloid-beta efflux: a measure of brain amyloid burden in a mouse model of Alzheimer's disease. Science 295:2264-2267.
    • (2002) Science , vol.295 , pp. 2264-2267
    • DeMattos, R.B.1    Bales, K.R.2    Cummins, D.J.3    Paul, S.M.4    Holtzman, D.M.5
  • 48
    • 0031985336 scopus 로고    scopus 로고
    • Mature microglia resemble immature antigen-presenting cells
    • Carson MJ, CR Reilly, JG Sutcliffe and D Lo. (1998). Mature microglia resemble immature antigen-presenting cells. Glia 22:72-85.
    • (1998) Glia , vol.22 , pp. 72-85
    • Carson, M.J.1    Reilly, C.R.2    Sutcliffe, J.G.3    Lo, D.4
  • 49
    • 34248360349 scopus 로고    scopus 로고
    • CD40/CD40L dyad in the inflammatory and immune responses in the central nervous system
    • Chen K, J Huang, W Gong, L Zhang, P Yu and JM Wang. (2006). CD40/CD40L dyad in the inflammatory and immune responses in the central nervous system. Cell Mol Immunol 3:163-169.
    • (2006) Cell Mol Immunol , vol.3 , pp. 163-169
    • Chen, K.1    Huang, J.2    Gong, W.3    Zhang, L.4    Yu, P.5    Wang, J.M.6
  • 50
    • 0034711317 scopus 로고    scopus 로고
    • CD45 inhibits CD40L-induced microglial activation via negative regulation of the Src/p44/42 MAPK pathway
    • Tan J, T Town and M Mullan. (2000). CD45 inhibits CD40L-induced microglial activation via negative regulation of the Src/p44/42 MAPK pathway. J Biol Chem 275:37224-37231.
    • (2000) J Biol Chem , vol.275 , pp. 37224-37231
    • Tan, J.1    Town, T.2    Mullan, M.3
  • 51
    • 31144457903 scopus 로고    scopus 로고
    • CD40 expression by microglial cells is required for their completion of a two-step activation process during central nervous system autoimmune inflammation
    • Ponomarev ED, LP Shriver and BN Dittel. (2006). CD40 expression by microglial cells is required for their completion of a two-step activation process during central nervous system autoimmune inflammation. J Immunol 176:1402-1410.
    • (2006) J Immunol , vol.176 , pp. 1402-1410
    • Ponomarev, E.D.1    Shriver, L.P.2    Dittel, B.N.3
  • 52
    • 0037110640 scopus 로고    scopus 로고
    • Modeling Alzheimer's disease immune therapy mechanisms: Interactions of human postmortem microglia with antibody-opsonized amyloid beta peptide
    • Lue LF and DG Walker. (2002). Modeling Alzheimer's disease immune therapy mechanisms: interactions of human postmortem microglia with antibody-opsonized amyloid beta peptide. J Neurosci Res 70:599-610.
    • (2002) J Neurosci Res , vol.70 , pp. 599-610
    • Lue, L.F.1    Walker, D.G.2
  • 53
    • 0035066332 scopus 로고    scopus 로고
    • Alzheimer's disease: Genes, proteins, and therapy
    • Selkoe DJ. (2001). Alzheimer's disease: genes, proteins, and therapy. Physiol Rev 81:741-766.
    • (2001) Physiol Rev , vol.81 , pp. 741-766
    • Selkoe, D.J.1
  • 54
    • 0036323445 scopus 로고    scopus 로고
    • Alzheimer disease and cerebrovascular pathology: An update
    • Jellinger KA. (2002). Alzheimer disease and cerebrovascular pathology: an update. J Neural Transm 109:813-836.
    • (2002) J Neural Transm , vol.109 , pp. 813-836
    • Jellinger, K.A.1
  • 55
    • 0035950225 scopus 로고    scopus 로고
    • Clearing the brain's amyloid cobwebs
    • Selkoe DJ. (2001). Clearing the brain's amyloid cobwebs. Neuron 32:177-180.
    • (2001) Neuron , vol.32 , pp. 177-180
    • Selkoe, D.J.1
  • 56
    • 0038809827 scopus 로고    scopus 로고
    • Amyloidosis of cerebral arteries
    • Vinters HV and ES Farag. (2003). Amyloidosis of cerebral arteries. Adv Neurol 92:105-112.
    • (2003) Adv Neurol , vol.92 , pp. 105-112
    • Vinters, H.V.1    Farag, E.S.2
  • 57
    • 14544285064 scopus 로고    scopus 로고
    • Amyloid-beta neurotoxicity is mediated by FISH adapter protein and ADAM12 metalloprotease activity
    • Malinin NL, S Wright, P Seubert, D Schenk and I Griswold-Prenner. (2005). Amyloid-beta neurotoxicity is mediated by FISH adapter protein and ADAM12 metalloprotease activity. Proc Natl Acad Sci USA 102:3058-3063.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 3058-3063
    • Malinin, N.L.1    Wright, S.2    Seubert, P.3    Schenk, D.4    Griswold-Prenner, I.5
  • 58
    • 1542283611 scopus 로고    scopus 로고
    • Neuroinflammatory perspectives on the two faces of Alzheimer's disease
    • Eikelenboom P and WA van Gool. (2004). Neuroinflammatory perspectives on the two faces of Alzheimer's disease. J Neural Transm 111:281-294.
    • (2004) J Neural Transm , vol.111 , pp. 281-294
    • Eikelenboom, P.1    van Gool, W.A.2
  • 59
    • 19944421400 scopus 로고    scopus 로고
    • The neuroinflammatory response in plaques and amyloid angiopathy in Alzheimer's disease: Therapeutic implications
    • Rozemuller AJ, WA van Gool and P Eikelenboom. (2005). The neuroinflammatory response in plaques and amyloid angiopathy in Alzheimer's disease: therapeutic implications. Curr Drug Targets CNS Neurol Disord 4:223-233.
    • (2005) Curr Drug Targets CNS Neurol Disord , vol.4 , pp. 223-233
    • Rozemuller, A.J.1    van Gool, W.A.2    Eikelenboom, P.3
  • 60
    • 27644457417 scopus 로고    scopus 로고
    • The choroid plexus removes beta-amyloid from brain cerebrospinal fluid
    • Crossgrove JS, GJ Li and W Zheng. (2005). The choroid plexus removes beta-amyloid from brain cerebrospinal fluid. Exp Biol Med (Maywood) 230:771-776.
    • (2005) Exp Biol Med (Maywood) , vol.230 , pp. 771-776
    • Crossgrove, J.S.1    Li, G.J.2    Zheng, W.3
  • 61
    • 0036319503 scopus 로고    scopus 로고
    • Plaque-associated disruption of CSF and plasma amyloid-beta (Abeta) equilibrium in a mouse model of Alzheimer's disease
    • DeMattos RB, KR Bales, M Parsadanian, MA O'Dell, EM Foss, SM Paul and DM Holtzman. (2002). Plaque-associated disruption of CSF and plasma amyloid-beta (Abeta) equilibrium in a mouse model of Alzheimer's disease. J Neurochem 81:229-236.
    • (2002) J Neurochem , vol.81 , pp. 229-236
    • DeMattos, R.B.1    Bales, K.R.2    Parsadanian, M.3    O'Dell, M.A.4    Foss, E.M.5    Paul, S.M.6    Holtzman, D.M.7
  • 64
    • 12344327823 scopus 로고    scopus 로고
    • Brain-to-blood transporters for endogenous substrates and xenobiotics at the blood-brain barrier: An overview of biology and methodology
    • Terasaki T and S Ohtsuki. (2005). Brain-to-blood transporters for endogenous substrates and xenobiotics at the blood-brain barrier: an overview of biology and methodology. NeuroRx 2:63-72.
    • (2005) NeuroRx , vol.2 , pp. 63-72
    • Terasaki, T.1    Ohtsuki, S.2
  • 65
    • 0032487625 scopus 로고    scopus 로고
    • Alzheimer's beta-amyloid peptides induce inflammatory cascade in human vascular cells: The roles of cytokines and CD40
    • Suo Z, J Tan, A Placzek, F Crawford, C Fang and M Mullan. (1998). Alzheimer's beta-amyloid peptides induce inflammatory cascade in human vascular cells: the roles of cytokines and CD40. Brain Res 807:110-117.
    • (1998) Brain Res , vol.807 , pp. 110-117
    • Suo, Z.1    Tan, J.2    Placzek, A.3    Crawford, F.4    Fang, C.5    Mullan, M.6
  • 66
    • 0030793527 scopus 로고    scopus 로고
    • Astroglial overproduction of TGF-beta 1 enhances inflammatory central nervous system disease in transgenic mice
    • Wyss-Coray T, P Borrow, MJ Brooker and L Mucke. (1997). Astroglial overproduction of TGF-beta 1 enhances inflammatory central nervous system disease in transgenic mice. J Neuroimmunol 77:45-50.
    • (1997) J Neuroimmunol , vol.77 , pp. 45-50
    • Wyss-Coray, T.1    Borrow, P.2    Brooker, M.J.3    Mucke, L.4
  • 67
    • 0034744296 scopus 로고    scopus 로고
    • TGF-beta1 promotes microglial amyloid-beta clearance and reduces plaque burden in transgenic mice
    • Wyss-Coray T, C Lin, F Yan, GQ Yu, M Rohde, L McConlogue, E Masliah and L Mucke. (2001). TGF-beta1 promotes microglial amyloid-beta clearance and reduces plaque burden in transgenic mice. Nature Med 7:612-618.
    • (2001) Nature Med , vol.7 , pp. 612-618
    • Wyss-Coray, T.1    Lin, C.2    Yan, F.3    Yu, G.Q.4    Rohde, M.5    McConlogue, L.6    Masliah, E.7    Mucke, L.8
  • 70
    • 0028109334 scopus 로고
    • Decreased macrophage colony-stimulating factor mRNA expression from activated cord versus adult mononuclear cells: Altered posttranscriptional stability
    • Suen Y, SM Lee, J Schreurs, E Knoppel and MS Cairo. (1994). Decreased macrophage colony-stimulating factor mRNA expression from activated cord versus adult mononuclear cells: altered posttranscriptional stability. Blood 84:4269-4277.
    • (1994) Blood , vol.84 , pp. 4269-4277
    • Suen, Y.1    Lee, S.M.2    Schreurs, J.3    Knoppel, E.4    Cairo, M.S.5
  • 71
    • 4744358048 scopus 로고    scopus 로고
    • Central nervous system entry of peripherally injected umbilical cord blood cells is not required for neuroprotection in stroke
    • Borlongan CV, M Hadman, CD Sanberg and PR Sanberg. (2004). Central nervous system entry of peripherally injected umbilical cord blood cells is not required for neuroprotection in stroke. Stroke 35:2385-2389.
    • (2004) Stroke , vol.35 , pp. 2385-2389
    • Borlongan, C.V.1    Hadman, M.2    Sanberg, C.D.3    Sanberg, P.R.4
  • 74
    • 24744467358 scopus 로고    scopus 로고
    • Microglial phagocytosis induced by fibrillar beta-amyloid and IgGs are differentially regulated by proinflammatory cytokines
    • Koenigsknecht-Talboo J and GE Landreth. (2005). Microglial phagocytosis induced by fibrillar beta-amyloid and IgGs are differentially regulated by proinflammatory cytokines. J Neurosci 25:8240-8249.
    • (2005) J Neurosci , vol.25 , pp. 8240-8249
    • Koenigsknecht-Talboo, J.1    Landreth, G.E.2
  • 75
    • 34347268434 scopus 로고    scopus 로고
    • Brain-immune communication pathways
    • Quan N and WA Banks. (2007). Brain-immune communication pathways. Brain Behav Immun 21:727-735.
    • (2007) Brain Behav Immun , vol.21 , pp. 727-735
    • Quan, N.1    Banks, W.A.2
  • 76
    • 32344440522 scopus 로고    scopus 로고
    • Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease
    • Simard AR, D Soulet, G Gowing, JP Julien and S Rivest. (2006). Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease. Neuron 49:489-502.
    • (2006) Neuron , vol.49 , pp. 489-502
    • Simard, A.R.1    Soulet, D.2    Gowing, G.3    Julien, J.P.4    Rivest, S.5
  • 77
    • 0030248270 scopus 로고    scopus 로고
    • Microglial cells internalize aggregates of the Alzheimer's disease amyloid beta-protein via a scavenger receptor
    • Paresce DM, RN Ghosh and FR Maxfield. (1996). Microglial cells internalize aggregates of the Alzheimer's disease amyloid beta-protein via a scavenger receptor. Neuron 17:553-565.
    • (1996) Neuron , vol.17 , pp. 553-565
    • Paresce, D.M.1    Ghosh, R.N.2    Maxfield, F.R.3
  • 78
    • 0030664076 scopus 로고    scopus 로고
    • Slow degradation of aggregates of the Alzheimer's disease amyloid beta-protein by microglial cells
    • Paresce DM, H Chung and FR Maxfield. (1997). Slow degradation of aggregates of the Alzheimer's disease amyloid beta-protein by microglial cells. J Biol Chem 272:29390-29397.
    • (1997) J Biol Chem , vol.272 , pp. 29390-29397
    • Paresce, D.M.1    Chung, H.2    Maxfield, F.R.3
  • 79
    • 0033527637 scopus 로고    scopus 로고
    • Uptake, degradation, and release of fibrillar and soluble forms of Alzheimer's amyloid beta-peptide by microglial cells
    • Chung H, MI Brazil, TT Soe and FR Maxfield. (1999). Uptake, degradation, and release of fibrillar and soluble forms of Alzheimer's amyloid beta-peptide by microglial cells. J Biol Chem 274:32301-32308.
    • (1999) J Biol Chem , vol.274 , pp. 32301-32308
    • Chung, H.1    Brazil, M.I.2    Soe, T.T.3    Maxfield, F.R.4
  • 80
    • 0034901679 scopus 로고    scopus 로고
    • On the role of peripheral macrophages during active experimental allergic encephalomyelitis (EAE)
    • Imrich H and K Harzer. (2001). On the role of peripheral macrophages during active experimental allergic encephalomyelitis (EAE). J Neural Transm 108:379-395.
    • (2001) J Neural Transm , vol.108 , pp. 379-395
    • Imrich, H.1    Harzer, K.2
  • 82
    • 27744464859 scopus 로고    scopus 로고
    • The microglial " activation" continuum: From innate to adaptive responses
    • Town T, V Nikolic and J Tan. (2005). The microglial " activation" continuum: from innate to adaptive responses. J Neuroinflammation 2:24.
    • (2005) J Neuroinflammation , vol.2 , pp. 24
    • Town, T.1    Nikolic, V.2    Tan, J.3


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