Induction of CD40 on human endothelial cells by Alzheimer's β-amyloid peptides

Brain Research Bulletin

Volumn 50, Issue 2, 1999, Pages 143-148

  Tan, J ^a   Town, T ^a   Suo, Z ^a   Wu, Y ^a   Song, S ^b   Kundtz, A ^a   Kroeger, J ^c   Humphrey, J ^a   Crawford, F ^a   Mullan, M ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b UNIVERSITY OF SOUTH FLORIDA   (United States)

^c H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

Author keywords

Amyloid; CD40; CD40L; Human endothelial cell; IFN ; IL 1

Indexed keywords

AMYLOID BETA PROTEIN; CD40 ANTIGEN; INTERLEUKIN 1BETA;

ALZHEIMER DISEASE; ARTICLE; CONTROLLED STUDY; ENDOTHELIUM INJURY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; INFLAMMATION; NERVE DEGENERATION; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VASCULAR ENDOTHELIUM;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANTIGENS, CD40; BLOTTING, WESTERN; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GENE EXPRESSION; HUMANS; INTERFERON TYPE II; INTERLEUKIN-1; PEPTIDE FRAGMENTS; POLYMERASE CHAIN REACTION;

EID: 0032851269     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0361-9230(99)00122-7     Document Type: Article

References (33)

1. Armitage R.J., Fanslow W.C., Strockbine L., Sato T.A., Clifford K.N., Macduff B.M., Anderson D.M., Gimpel S.D., Davis-Smith T., Maliszewski C.R., Clark E.A., Smith C.A., Grabstein K.H., Cosman D., Spriggs M.K. Molecular and biological characterization of a murine ligand for CD40. Nature. 357:1992;80-82.
2. Banchereau J., Bazan F., Blanchard D., Briere F., Galizzi J.P., van Kooten C., Liu Y.J., Rousset F., Saeland S. The CD40 antigen and its ligand. Annu. Rev. Immunol. 12:1994;881-922.
3. Campbell K.A., Ovendale P.J., Kennedy M.K., Fanslow W.C., Reed S.G., Maliszewski C.R. CD40 ligand is required for protective cell-mediated immunity to Leishmania major. Immunity. 4:1996;283-289.
4. Denfeld R.W., Hollenbaugh D., Fehrebach A., Weiss J.M., von Leoprechting A., Mai B., Voith U., Schopf E., Aruffo A., Simon J.C. CD40 is functionally expressed on human keratinocytes. Eur. J. Immunol. 26:1996;2329-2334.
5. Eikelenboom P., Zhan S.S., Kamphorst W., van der Valk P., Rozemuller J.M. Cellular and substrate adhesion molecular (integrins) and their ligands in cerebral amyloid plaques in Alzheimer's disease. Virchows. Arch. 424:1994;421-427.
6. Ellis R.J., Olichney J.M., Thal L.J., Mirra S.S., Morris J.C., Beekly D., Heyman A. Cerebral amyloid angiopathy in the brains of patients with Alzheimer's disease The CERAD experience, Part XV . Neurology. 46:1996;1592-1596.
7. Fukumoto Y., Shimokawa H., Kozai T., Kadokami T., Kuwata K., Yonemitsu Y., Kuga T., Egashira K., Sueishi K., Takeshita A. Vasculoprotective role of inducible nitric oxide synthase at inflammatory coronary lesions induced by chronic treatment with interleukin-1beta in pig in vivo. Circulation. 96:1997;3104-3111.
8. Gerritse K., Laman J.D., Noelle R.J., Aruffo A., Ledbetter J.A., Boersma W.J., Claassen E. CD40-CD40 ligand interactions in experimental allergic encephalomyelitis and multiple sclerosis. Proc. Natl. Acad. Sci. USA. 93:1996;2499-2504.
9. Grewal I.S., Xu J., Flavell R.A. Impairment of antigen-specific T-cell priming in mice lacking CD40 ligand. Nature. 378:1995;617-620.
10. Grewal I.S., Foellmer H.G., Grewal K.D., Xu J., Hardardottir F., Baron J.L., Janeway C.A. Jr, Flavell R.A. Requirement for CD40 ligand in costimulation induction, T cell activation, and experimental allergic encephalomyelitis. Science. 273:1996;1864-1867.
11. Higuchi Y., Miyakawa T., Shimoji A., Katsuragi S. Ultrastructural changes of blood vessels in the cerebral cortex in Alzheimer's disease. Jpn. J. Psychiatry. Neurol. 41:1987;283-290.
12. Hollenbaugh D., Mischel-Petty N., Edwards C.P., Simon J.C., Denfeld R.W., Kiener P.A., Aruffo A. Expression of functional CD40 by vascular endothelial cells. J. Exp. Med. 182:1995;33-40.
13. Hull M., Fiebich B.L., Lieb K., Strauss S., Berger M., Volk B., Bauer J. Interleukin-6-associated inflammatory processes in Alzheimer's disease new therapeutic options . Neurobiol. Aging. 17:1996;795-800.
14. Iadecola C., Zhang F., Niwa K., Eckman C., Turner S.K., Fisher E., Younkin S., Borchelt D.R., Hsiao K.K., Carlson G.A. SOD1 rescues cerebral endothelial dysfunction in mice overexpressing amyloid precursor protein. Nat. Neurosci. 2:1999;157-161.
15. Jahroudi N., Kitney J., Greenberger J.S., Bowser R. Endothelial cell dysfunction in response to intracellular overexpression of amyloid precursor protein. J. Neurosci. Res. 54:1998;828-839.
16. Kalaria R.N., Hedera P. Differential degeneration of the cerebral microvasculature in Alzheimer's disease. Neuroreport. 15:1995;477-480.
17. Karmann K., Hughes C.C.W., Schechner J., Fanslow W.C., Pober J.S. CD40 on human endothelial cells Inducibility by cytokines and functional regulation of adhesion molecular expression . Proc. Natl. Acad. Sci. USA. 92:1995;4342-4346.
18. Kawabe T., Naka T., Yoshida K., Tanaka T., Fujiwara H., Suematsu S., Yoshida N., Kishimoto T., Kikutani H. The immune responses in CD40-deficient mice impaired immunoglobulin class switching and germinal center formation . Immunity. 1:1994;167-178.
19. Mach F., Schonbeck U., Sukhova G.K., Bourcier T., Bonnefoy J.Y., Pober J.S., Libby P. Functional CD40 ligand is expressed on human vascular endothelial cells, smooth muscle cells, and macrophages Implications for CD40-CD40 ligand signaling in atherosclerosis . Proc. Natl. Acad. Sci. USA. 94:1997;1931-1936.
20. Maneiro E., Lombardi V.R., Lagares R., Cacabelos R. An experimental model to study the cytotoxic effects induced by beta-amyloid, histamine, LPS and serum from Alzheimer's patients on cultured rat endothelial cells. Methods Find. Exp. Clin. Pharmacol. 19:1997;5-12.
21. McGeer P.L., Rogers J. Anti-inflammatory agents as a therapeutic approach to Alzheimer's disease. Neurology. 42:1992;447-449.
22. McLellan, A. D.; Sorg, R. V.; Williams, L. A.; Hart, D. N. J. Human dendritic cells activate T lymphocytes via a CD40: CD40 ligand-dependent pathway. Eur. J. Immunol. 26:1204-1210; 1996.
23. Miwa T., Kamada S. The nucleotide sequence of a human smooth (enteric type) muscle gamma-actin cDNA. Nucleic Acid Res. 18:1990;4263-4268.
24. O'Banion M.K., Finch C.E. Inflammatory mechanisms in neurodegeneration and Alzheimer's disease The role of the complement system . Neurobiol. Aging. 17:1996;669-671.
25. Rogers J., Webster S., Lue L., Brachova L., Civin W.H., Emmerling M., Shivers B., Walker D., Mcgeer P. Inflammation and Alzheimer's disease pathogenesis. Neurobiol. Aging. 17:1996;681-686.
26. Schonbeck U., Mach F., Bonnefoy J.Y., Loppnow H., Flad H.D., Libby P. Ligation of CD40 activates interleukin 1β-converting enzyme (caspase-1) activity in vascular smooth muscle and endothelial cells and promotes elaboration of active interleukin 1β J. Biol. Chem. 272:1997;19569-19574.
27. Stuber E., Strober W., Neurath M. Blocking the CD40L-CD40 interaction in vivo specifically prevents the priming of T helper 1 cells through the inhibition of interleukin 12 secretion. J. Exp. Med. 183:1996;693-698.
28. Stamenkovic I., Clark E.A., Seed B.A. B-lymphocyte activation molecule related to nerve growth factor receptor and induced by cytokines in carcinomas. EMBO J. 8:1989;1403-1410.
29. 1-42 induced endothelial toxocity. Brain Res. 762:1997;144-152.
30. Tan J., Crucian B., Chang A., Argua E., Argua A., Dovhey S., Yu H. Interferon-γ-inducing factor elicits antitumor immunity in association with interferon-γ production. J. Immunother. 21:1998;48-55.
31. Verbeek, M. M.; Otte-Holler, I., Wesseling, P.; Ruiter, D. J.; de Waal, R. M. Differential expression of intercellular adhesion molecule-1 (ICAM-1) in the A beta-containing lesions in brains of patients with dementia of the Alzheimer's type. Acta Neuropothol. (Berl.) 91:608-615; 1996.
32. Thomas T., Thomas G., McLendon C., Sutton T., Mullan M. β-Amyloid-mediated vasoactivity and vascular endothelial damage. Nature. 380:1996;168-171.
33. Yang Y., Wilsom J.M. CD40 ligand-dependent T cell activation Requirement of B7-CD28 signaling through CD40 . Science. 273:1996;1862-1864.