메뉴 건너뛰기




Volumn 24, Issue 3, 2006, Pages 516-524

Characterization of amyloid deposition in the APPswe/PS1dE9 mouse model of Alzheimer disease

Author keywords

Alzheimer disease; Amyloid ; APPswe PS1dE9; Cerebral amyloid angiopathy; Transgenic mouse

Indexed keywords

AMYLOID BETA PROTEIN;

EID: 33750819632     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2006.08.017     Document Type: Article
Times cited : (607)

References (45)
  • 2
    • 13444301296 scopus 로고    scopus 로고
    • Mouse models of human neurodegenerative disorders: requirements for medication development
    • Bloom F.E., Reilly J.F., Redwine J.M., Wu C.C., Young W.G., and Morrison J.H. Mouse models of human neurodegenerative disorders: requirements for medication development. Arch. Neurol. 62 (2005) 185-187
    • (2005) Arch. Neurol. , vol.62 , pp. 185-187
    • Bloom, F.E.1    Reilly, J.F.2    Redwine, J.M.3    Wu, C.C.4    Young, W.G.5    Morrison, J.H.6
  • 4
    • 0035099136 scopus 로고    scopus 로고
    • Structural and functional disruption of vascular smooth muscle cells in a transgenic mouse model of amyloid angiopathy
    • Christie R., Yamada M., Moskowitz M., and Hyman B. Structural and functional disruption of vascular smooth muscle cells in a transgenic mouse model of amyloid angiopathy. Am. J. Pathol. 158 (2001) 1065-1071
    • (2001) Am. J. Pathol. , vol.158 , pp. 1065-1071
    • Christie, R.1    Yamada, M.2    Moskowitz, M.3    Hyman, B.4
  • 5
    • 0035116442 scopus 로고    scopus 로고
    • Growth arrest of individual senile plaques in a model of Alzheimer's disease observed by in vivo multiphoton microscopy
    • Christie R.H., Bacskai B.J., Zipfel W.R., Williams R.M., Kajdasz S.T., Webb W.W., and Hyman B.T. Growth arrest of individual senile plaques in a model of Alzheimer's disease observed by in vivo multiphoton microscopy. J. Neurosci. 21 (2001) 858-864
    • (2001) J. Neurosci. , vol.21 , pp. 858-864
    • Christie, R.H.1    Bacskai, B.J.2    Zipfel, W.R.3    Williams, R.M.4    Kajdasz, S.T.5    Webb, W.W.6    Hyman, B.T.7
  • 9
    • 8844285984 scopus 로고    scopus 로고
    • Mouse models of Alzheimer's disease: insight into treatment
    • German D.C., and Eisch A.J. Mouse models of Alzheimer's disease: insight into treatment. Rev. Neurosci. 15 (2004) 353-369
    • (2004) Rev. Neurosci. , vol.15 , pp. 353-369
    • German, D.C.1    Eisch, A.J.2
  • 10
    • 33745893209 scopus 로고    scopus 로고
    • Amyloid at the blood vessel wall
    • Hardy J., and Cullen K. Amyloid at the blood vessel wall. Nat. Med. 12 (2006) 756-757
    • (2006) Nat. Med. , vol.12 , pp. 756-757
    • Hardy, J.1    Cullen, K.2
  • 14
    • 0027490070 scopus 로고
    • The lack of accumulation of senile plaques or amyloid burden in Alzheimer's disease suggests a dynamic balance between amyloid deposition and resolution
    • Hyman B.T., Marzloff K., and Arriagada P.V. The lack of accumulation of senile plaques or amyloid burden in Alzheimer's disease suggests a dynamic balance between amyloid deposition and resolution. J. Neuropathol. Exp. Neurol. 52 (1993) 594-600
    • (1993) J. Neuropathol. Exp. Neurol. , vol.52 , pp. 594-600
    • Hyman, B.T.1    Marzloff, K.2    Arriagada, P.V.3
  • 15
    • 0028899724 scopus 로고
    • Quantitative analysis of senile plaques in Alzheimer disease: observation of log-normal size distribution and molecular epidemiology of differences associated with apolipoprotein E genotype and trisomy 21 (Down syndrome)
    • Hyman B.T., West H.L., Rebeck G.W., Buldyrev S.V., Mantegna R.N., Ukleja M., Havlin S., and Stanley H.E. Quantitative analysis of senile plaques in Alzheimer disease: observation of log-normal size distribution and molecular epidemiology of differences associated with apolipoprotein E genotype and trisomy 21 (Down syndrome). Proc. Natl. Acad. Sci. U. S. A. 92 (1995) 3586-3590
    • (1995) Proc. Natl. Acad. Sci. U. S. A. , vol.92 , pp. 3586-3590
    • Hyman, B.T.1    West, H.L.2    Rebeck, G.W.3    Buldyrev, S.V.4    Mantegna, R.N.5    Ukleja, M.6    Havlin, S.7    Stanley, H.E.8
  • 19
    • 0036323445 scopus 로고    scopus 로고
    • Alzheimer disease and cerebrovascular pathology: an update
    • Jellinger K.A. Alzheimer disease and cerebrovascular pathology: an update. J. Neural Transm. 109 (2002) 813-836
    • (2002) J. Neural Transm. , vol.109 , pp. 813-836
    • Jellinger, K.A.1
  • 20
    • 0035863055 scopus 로고    scopus 로고
    • Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease
    • Kawarabayashi T., Younkin L.H., Saido T.C., Shoji M., Ashe K.H., and Younkin S.G. Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease. J. Neurosci. 21 (2001) 372-381
    • (2001) J. Neurosci. , vol.21 , pp. 372-381
    • Kawarabayashi, T.1    Younkin, L.H.2    Saido, T.C.3    Shoji, M.4    Ashe, K.H.5    Younkin, S.G.6
  • 23
    • 9644252796 scopus 로고    scopus 로고
    • Longitudinal observation on CSF Abeta42 levels in young to middle-aged amyloid precursor protein/presenilin-1 doubly transgenic mice
    • Liu L., Herukka S.K., Minkeviciene R., van Groen T., and Tanila H. Longitudinal observation on CSF Abeta42 levels in young to middle-aged amyloid precursor protein/presenilin-1 doubly transgenic mice. Neurobiol. Dis. 17 (2004) 516-523
    • (2004) Neurobiol. Dis. , vol.17 , pp. 516-523
    • Liu, L.1    Herukka, S.K.2    Minkeviciene, R.3    van Groen, T.4    Tanila, H.5
  • 24
    • 0037444553 scopus 로고    scopus 로고
    • In vivo imaging of reactive oxygen species specifically associated with thioflavine S-positive amyloid plaques by multiphoton microscopy
    • McLellan M.E., Kajdasz S.T., Hyman B.T., and Bacskai B.J. In vivo imaging of reactive oxygen species specifically associated with thioflavine S-positive amyloid plaques by multiphoton microscopy. J. Neurosci. 23 (2003) 2212-2217
    • (2003) J. Neurosci. , vol.23 , pp. 2212-2217
    • McLellan, M.E.1    Kajdasz, S.T.2    Hyman, B.T.3    Bacskai, B.J.4
  • 26
    • 2542455536 scopus 로고    scopus 로고
    • Cerebral amyloid angiopathy plays a direct role in the pathogenesis of Alzheimer's disease. Pro-CAA position statement
    • (discussion 603-584)
    • Nicoll J.A., Yamada M., Frackowiak J., Mazur-Kolecka B., and Weller R.O. Cerebral amyloid angiopathy plays a direct role in the pathogenesis of Alzheimer's disease. Pro-CAA position statement. Neurobiol. Aging. 25 (2004) 589-597 (discussion 603-584)
    • (2004) Neurobiol. Aging. , vol.25 , pp. 589-597
    • Nicoll, J.A.1    Yamada, M.2    Frackowiak, J.3    Mazur-Kolecka, B.4    Weller, R.O.5
  • 29
    • 0032168460 scopus 로고    scopus 로고
    • Isoform-specific effects of human apolipoprotein E on brain function revealed in ApoE knockout mice: increased susceptibility of females
    • Raber J., Wong D., Buttini M., Orth M., Bellosta S., Pitas R.E., Mahley R.W., and Mucke L. Isoform-specific effects of human apolipoprotein E on brain function revealed in ApoE knockout mice: increased susceptibility of females. Proc. Natl. Acad. Sci. U. S. A. 95 (1998) 10914-10919
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , pp. 10914-10919
    • Raber, J.1    Wong, D.2    Buttini, M.3    Orth, M.4    Bellosta, S.5    Pitas, R.E.6    Mahley, R.W.7    Mucke, L.8
  • 33
    • 20044383377 scopus 로고    scopus 로고
    • Episodic-like memory deficits in the APPswe/PS1dE9 mouse model of Alzheimer's disease: relationships to beta-amyloid deposition and neurotransmitter abnormalities
    • Savonenko A., Xu G.M., Melnikova T., Morton J.L., Gonzales V., Wong M.P., Price D.L., Tang F., Markowska A.L., and Borchelt D.R. Episodic-like memory deficits in the APPswe/PS1dE9 mouse model of Alzheimer's disease: relationships to beta-amyloid deposition and neurotransmitter abnormalities. Neurobiol. Dis. 18 (2005) 602-617
    • (2005) Neurobiol. Dis. , vol.18 , pp. 602-617
    • Savonenko, A.1    Xu, G.M.2    Melnikova, T.3    Morton, J.L.4    Gonzales, V.5    Wong, M.P.6    Price, D.L.7    Tang, F.8    Markowska, A.L.9    Borchelt, D.R.10
  • 34
    • 0038755949 scopus 로고    scopus 로고
    • Normal cognitive behavior in two distinct congenic lines of transgenic mice hyperexpressing mutant APP SWE
    • Savonenko A.V., Xu G.M., Price D.L., Borchelt D.R., and Markowska A.L. Normal cognitive behavior in two distinct congenic lines of transgenic mice hyperexpressing mutant APP SWE. Neurobiol. Dis. 12 (2003) 194-211
    • (2003) Neurobiol. Dis. , vol.12 , pp. 194-211
    • Savonenko, A.V.1    Xu, G.M.2    Price, D.L.3    Borchelt, D.R.4    Markowska, A.L.5
  • 36
    • 0032211830 scopus 로고    scopus 로고
    • The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease
    • Selkoe D.J. The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease. Trends Cell Biol. 8 (1998) 447-453
    • (1998) Trends Cell Biol. , vol.8 , pp. 447-453
    • Selkoe, D.J.1
  • 37
    • 33745923170 scopus 로고    scopus 로고
    • The ups and downs of Abeta
    • Selkoe D.J. The ups and downs of Abeta. Nat. Med. 12 (2006) 758-759
    • (2006) Nat. Med. , vol.12 , pp. 758-759
    • Selkoe, D.J.1
  • 38
    • 0034551780 scopus 로고    scopus 로고
    • Presenilin-1 P264L knock-in mutation: differential effects on abeta production, amyloid deposition, and neuronal vulnerability
    • Siman R., Reaume A.G., Savage M.J., Trusko S., Lin Y.G., Scott R.W., and Flood D.G. Presenilin-1 P264L knock-in mutation: differential effects on abeta production, amyloid deposition, and neuronal vulnerability. J. Neurosci. 20 (2000) 8717-8726
    • (2000) J. Neurosci. , vol.20 , pp. 8717-8726
    • Siman, R.1    Reaume, A.G.2    Savage, M.J.3    Trusko, S.4    Lin, Y.G.5    Scott, R.W.6    Flood, D.G.7
  • 39
    • 26844449402 scopus 로고    scopus 로고
    • Transgenic models of Alzheimer's disease: learning from animals
    • Spires T.L., and Hyman B.T. Transgenic models of Alzheimer's disease: learning from animals. NeuroRx 2 (2005) 423-437
    • (2005) NeuroRx , vol.2 , pp. 423-437
    • Spires, T.L.1    Hyman, B.T.2
  • 41
    • 20044366064 scopus 로고    scopus 로고
    • Cerebrovascular disease and the pathophysiology of Alzheimer's disease. Implications for therapy
    • Weller R.O., Cohen N.R., and Nicoll J.A. Cerebrovascular disease and the pathophysiology of Alzheimer's disease. Implications for therapy. Panminerva Med. 46 (2004) 239-251
    • (2004) Panminerva Med. , vol.46 , pp. 239-251
    • Weller, R.O.1    Cohen, N.R.2    Nicoll, J.A.3
  • 42
    • 0034095485 scopus 로고    scopus 로고
    • Cerebral amyloid angiopathy: accumulation of A beta in interstitial fluid drainage pathways in Alzheimer's disease
    • Weller R.O., Massey A., Kuo Y.M., and Roher A.E. Cerebral amyloid angiopathy: accumulation of A beta in interstitial fluid drainage pathways in Alzheimer's disease. Ann. N. Y. Acad. Sci. 903 (2000) 110-117
    • (2000) Ann. N. Y. Acad. Sci. , vol.903 , pp. 110-117
    • Weller, R.O.1    Massey, A.2    Kuo, Y.M.3    Roher, A.E.4
  • 43
    • 0034736182 scopus 로고    scopus 로고
    • Quantitative histological analysis of amyloid deposition in Alzheimer's double transgenic mouse brain
    • Wengenack T.M., Whelan S., Curran G.L., Duff K.E., and Poduslo J.F. Quantitative histological analysis of amyloid deposition in Alzheimer's double transgenic mouse brain. Neuroscience 101 (2000) 939-944
    • (2000) Neuroscience , vol.101 , pp. 939-944
    • Wengenack, T.M.1    Whelan, S.2    Curran, G.L.3    Duff, K.E.4    Poduslo, J.F.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.