High-throughput target validation in model organisms

Drug Discovery Today: TARGETS

Volumn 3, Issue 5, 2004, Pages 191-197

  Doan, Thanh N ^a   Eilertson, Carmen D ^a   Rubinstein, Amy L ^a  

^a Zygogen LLC   (United States)

Author keywords

Biochemistry; Chemical Biology; chemical genetics; Drug Discovery; Genetics; model organisms; morpholinos; RNAi; target validation; zebrafish

Indexed keywords

ATORVASTATIN; FLUOXETINE; RNA;

BIOLOGICAL MODEL; CAENORHABDITIS ELEGANS; CHEMICAL GENETICS; CHROMOSOME ANALYSIS; CORRELATION ANALYSIS; COST CONTROL; DEGENERATIVE DISEASE; DISEASE ACTIVITY; DISEASE MODEL; DROSOPHILA; DRUG ACTIVITY; DRUG MECHANISM; DRUG SCREENING; DRUG TARGETING; GENE DELETION; GENE FUNCTION; GENE INSERTION; GENE TECHNOLOGY; GENETIC ANALYSIS; GENETIC SCREENING; GENOME ANALYSIS; HUMAN; INVERTEBRATE; KNOCKOUT GENE; MODEL; MOLECULE; MUTAGENESIS; NEMATODE; NONHUMAN; PHENOTYPE; REVIEW; TIME; VALIDATION PROCESS; ZEBRA FISH;

EID: 4644279572     PISSN: 17418372     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1741-8372(04)02452-1     Document Type: Review

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