Drugs that induce repolarization abnormalities cause bradycardia in zebrafish

Circulation

Volumn 107, Issue 10, 2003, Pages 1355-1358

  Milan, David J ^a   Peterson, Travis A ^a   Ruskin, Jeremy N ^a   Peterson, Randall T ^a   MacRae, Calum A ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b Cardiovascular Research Center   (United States)

Author keywords

Arrhythmia; Drugs; Electrophysiology; Genes

Indexed keywords

ACICLOVIR; AMANTADINE; AMIODARONE; AMITRIPTYLINE; ASTEMIZOLE; AZITHROMYCIN; BACLOFEN; CAPTOPRIL; CARBAMAZEPINE; CARBIDOPA; CEFTRIAXONE; CHLORPROMAZINE; CIMETIDINE; CIPROFLOXACIN; CISAPRIDE; CLONIDINE; COLCHICINE; DANTROLENE; DEXAMETHASONE; DIGITOXIN; DOBUTAMINE; ERYTHROMYCIN; ETOPOSIDE; FUROSEMIDE; GENISTEIN; HALOPERIDOL; KETOCONAZOLE; MINOXIDIL; TERFENADINE; UNINDEXED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATRIOVENTRICULAR BLOCK; BRADYCARDIA; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; ELECTROPHYSIOLOGY; EMBRYO; HEART RATE; HEART REPOLARIZATION; KNOCKOUT GENE; LONG QT SYNDROME; NONHUMAN; PRIORITY JOURNAL; TORSADE DES POINTES; ZEBRA FISH;

ANIMALS; ARRHYTHMIA; BRADYCARDIA; CATION TRANSPORT PROTEINS; DRUG INTERACTIONS; ELECTRIC CONDUCTIVITY; ETHER-A-GO-GO POTASSIUM CHANNELS; HEART BLOCK; HEART RATE; OLIGONUCLEOTIDES, ANTISENSE; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED; ZEBRAFISH;

EID: 0037453021     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000061912.88753.87     Document Type: Article

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